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Tesis sobre el tema "Carbohydrate"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 25 de julio de 2025

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1

Drinnan, Nicholas Barry. "Towards the synthesis of biologically active carbohydrates and carbohydrate mimetics /." [St. Lucia, Qld], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18237.pdf.

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2

Hill, Anthony David. "Computational methods in the study of carbohydrates and carbohydrate-active enzymes." [Ames, Iowa : Iowa State University], 2006.

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3

Evans, Richard. "Carbohydrate biomimetics." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.534195.

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4

Houtkooper, Linda, and Jaclyn Maurer. "Carbohydrate Needs." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2006. http://hdl.handle.net/10150/146628.

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5

Promsawan, Netnapa. "Glycosylated Helices in the Study of Carbohydrate-Carbohydrate Interactions." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492505.

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Carbohydrate-Carbohydrate interactions (CCIs) operate in a number of biologically significant environments. These carbohydrate based interactions on cell surfaces, which have been shown to be highly specific and polyvalent, are believed to mediate cell recognition and adhesion within biological processes. Two synthetic glycosylated scaffolds have been synthesised as model systems and the scaffolds chosen were designed to orientate interacting carbohydrates close in space to one another thereby allowing the study of these important CCIs.
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6

Simpson, Graham L. "Molecular scaffolds in the study of carbohydrate-carbohydrate interactions." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289639.

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7

Gordon, Andrew H. "Helical scaffolds in the study of carbohydrate-carbohydrate interactions." Thesis, University of Bristol, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435738.

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8

García, Christian Arturo Fernández. "Developing synthetic tools for the study of carbohydrate-carbohydrate interactions." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556721.

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Carbohydrate-carbohydrate interactions (CCIs) have been shown to be an important interaction in molecular recognition. These interactions present characteristics such as the synergistic effect with other interactions e.g. protein-protein interactions, specificity, polyvalency and in some cases requirement of divalent cations. CCIs remain insufficiently documented due to the weakness of such an interaction, which is difficult to probe by classical techniques and study at the molecular level in a monovalent system has not been performed. In order to study the CCI, a peptide based on alanine and
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9

Smith, Martin D. "Carbohydrate amino acids." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302123.

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10

Johnson, Stephen W. "Carbohydrate-derived peptidomimetics." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401098.

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11

Proctor, Mark Richard. "Carbohydrate modifying enzymes." Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416647.

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12

McMahon, Stephen Andrew. "Protein-carbohydrate recognition." Thesis, University of St Andrews, 1999. http://hdl.handle.net/10023/14045.

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Protein-carbohydrate recognition is an important target for inhibitor development. Improved inhibitor design requires a fundamental molecular basis of these interactions. This thesis describes the preliminary structural studies on three carbohydrate processing enzymes, UDP-galactopyranose mutase, alpha-D-glucose-1-phosphate thymidylyltransferase and TDP-glucose 4,6-dehydratase. These enzymes are found in important human pathogens such as Mycobacterium tuberculosis and Salmonella typhimurium. The major focus of the thesis has been on UDP-galactopyranose mutase, the enzyme responsible for cataly
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13

Moothoo, Davina Noelle. "Protein-carbohydrate interactions." Thesis, University of St Andrews, 1998. http://hdl.handle.net/10023/14528.

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Carbohydrates are ubiquitous in nature and have become the focus of much scientific investigation. The proteins which recognise carbohydrates have become widely used in the areas of cell and molecular biology. Protein - carbohydrate interactions have been probed by theoretical, structural and thermodynamic techniques. The lectins are a class of carbohydrate binding proteins which bind carbohydrates through non covalent interactions such as hydrogen bonds and van der Waals interactions. In addition to these interactions, other factors play an important role in determining affinity such as carbo
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14

Pei, Zhichao. "Carbohydrate Synthesis and Study of Carbohydrate-Lectin Interactions Using QCM Biosensors and Microarray Technologies." Doctoral thesis, Stockholm : Chemical Science and Engineering, KTH, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4177.

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15

Ramstadius, Clinton. "Synthesis of Carbohydrate Mimics and Development of a Carbohydrate Epimerisation Method." Doctoral thesis, Stockholms universitet, Institutionen för organisk kemi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-45855.

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In this thesis the synthesis of several hydrolytically stable carbohydrate mimics with the potential to function as glycosidase or lectin inhibitors are described. This work is presented in Chapters 2-5. Chapters 2 and 3 describe synthetic efforts for producing carbasugars, and include the first synthesis of 1,2-bis-epi-valienamine and the preparation of two previously known aminocarbasugars. All three compounds were synthesised starting from D-mannose, using ring-closing metathesis as the key step. 1,2-Bis-epi-valienamine was found to inhibit Cellulomonas fimi β-mannosidase with a Ki value of
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16

Skead, Benjamin M. "Research in carbohydrate chemistry." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358724.

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17

Glew, Mandy. "Self-assembling carbohydrate systems." Thesis, University of Hull, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301487.

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18

Hasson, Christopher J. "Carbohydrate metabolism and aging." Virtual Press, 1987. http://liblink.bsu.edu/uhtbin/catkey/490219.

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It has been widely recognized that aging will cause a profound decrease in glucose tolerance end increase insulin resistance. These changes have been found to occur at a relatively early age. Narimiya [54], has documented these changes in younger rots end has shown alterations in glycogen metabolism to occur prior to nine months of age. Exercise in the form of running has been shown to attenuate these changes. In Vivo, glucose, insulin end muscle glycogen have interrelated functions. The role of muscle glycogen is to provide energy for the muscle's contractile process. Insulin is needed at
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19

Fowle, Chris. "Carbohydrate directed photoaffinity labelling." Thesis, University of Bath, 2018. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760976.

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Glycoproteins have diverse and essential roles within biological systems. They are formed by enzymatic addition of saccharides to proteins during, or shortly after, translation. However, saccharides can also react with proteins non-enzymatically, a process termed glycation, which can cause impaired function and improper folding. Glycated proteins further react to form advanced glycation end-products, which have been implicated in the pathogenesis and progress of many diseases. Due to this pathological effect, glycation has been studied as a potential biomarker of these diseases. Photoaffinity
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20

Jordaan, Michelle Bernitta. "Effect of processing on the starch and glycemic properties of Digitaria spp." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/2024.

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Thesis (MTech (Food Technology))--Cape Peninsula University of Technology, 2013.<br>Acha starch was isolated and purified from clean and milled acha grain. Functional, thermal and physicochemical properties of acha starch were analysed using appropriate methods. Wheat starch was used as the reference standard. Acha bread from acha grain was baked and the consumer sensory acceptability was evaluated and white wheat bread was used as the reference standard. The effect of baking, boiling, steaming and microwaving on the starch and glycemic properties of the acha starch was evaluated. With
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21

Mendlik, Matthew T. "Syntheses and investigations of 2,6-dideoxysugars contained in diverse bioactive compounds." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1120673161.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from second page of PDF file. Document formatted into pages; contains xix, 347 p.; also includes graphics. Includes bibliographical references (p. 183-192). Available online via OhioLINK's ETD Center
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22

Diswall, Mette. "Biochemical studies of carbohydrate blood group antigens : carbohydrate phenotype in relation to cellular glycosyltransferases /." Göteborg: University of Gothenburg, Institute of Clinical Sciences, Dept. of Surgery, 2009. http://hdl.handle.net/2077/20042.

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23

Marín, Ferré Irene. "Stereoselective reactions in carbohydrate synthesis." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/76720.

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La Tesis que se presenta trata sobre el desarrollo de nuevos métodos selectivos de síntesis de carbohidratos. En la primera parte de la tesis se estudió la epoxidación de glicales utilizando catalizadores de Mo y ácido meta-cloroperbenzoico (MCPBA), en relación con la obtención de mano-oligosacáridos. En todos los casos estudiados, el epóxido formado se abría in situ para dar lugar al correspondiente diol o glicósido. Se observó un efecto director por parte de los hidroxilos libres, lo que permitía obtener derivados de manosa a partir de glucosa. En el caso del Mo, los resultados figuran entr
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24

Kubo, Shiori. "Nanostructured carbohydrate-derived carbonaceous materials." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5315/.

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Nanoporous carbon materials are widely used in industry as adsorbents or catalyst supports, whilst becoming increasingly critical to the developing fields of energy storage / generation or separation technologies. In this thesis, the combined use of carbohydrate hydrothermal carbonisation (HTC) and templating strategies is demonstrated as an efficient route to nanostructured carbonaceous materials. HTC is an aqueous-phase, low-temperature (e.g. 130 – 200 °C) carbonisation, which proceeds via dehydration / poly-condensation of carbon precursors (e.g. carbohydrates and their derivatives), allowi
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25

Tontini, Marta. "Characterization of carbohydrate based vaccines." Phd thesis, Université de Cergy Pontoise, 2012. http://tel.archives-ouvertes.fr/tel-00825838.

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CHARACTERIZATION OF CARBOHYDRATE BASED VACCINES Variables influencing the immunogenicity and physicochemical properties of glycoconjugate vaccinesMany aspects can influence the immunogenicity of conjugate vaccines and the main variables investigated so far are the size of the saccharide moiety, the saccharide:protein ratio in the purified conjugate, the conjugation strategy, the nature of the spacer and the protein carrier. The size of the saccharide moiety and saccharide/protein ratio were investigated in different works such as Seppälä and Mäkelä in one of the first studies on the effect of
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26

Hughes, David J. "Synthetic studies in carbohydrate chemistry." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357421.

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27

Chong, Mary. "Mechnisms of carbohydrate-induced hypertriacylglycerolaemia." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437044.

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28

Wood, Andrew Joseph. "New methods for carbohydrate annulation." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34001.

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Chapter 1 describes the synthesis of a 1,4-dicarbonyl compound 1 which was constructed by a sequence involving opening of a protected glucose epoxide with allyl magnesium chloride, alkylation and Wacker oxidation; the 1,4-dicarbonyl compound 1 readily underwent cyclisation under basic conditions to produce the cyclopentaannulated sugar derivative 2. Treatment of the cyclopentaannulated sugar derivative with N-bromosuccinimide and subsequent treatment with activated zinc completed the fragmentation of 2 to furnish the cyclopentanes 3. Chapter 2 describes the reduction of 2 which furnished a mix
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29

Dwivedi, Padmanabh. "Carbohydrate starvation and plant respiration." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624182.

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30

Brown, Martyn A. "Phosphorus and arsenic carbohydrate derivatives." Thesis, University of Aberdeen, 1993. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU552502.

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A series of O-diphenylphosphinyl monosaccharide derivatives, e.g. 1,2:5,6-di-O-cyclohexylidene-3-O-diphenyl phosphinyl--D-glucofuranose [60], has been synthesised by reaction of a free hydroxy group in a sugar with Ph_2PCl. C-Diphenylphosphinyl and diphenylarsino derivatives, e.g. methyl 4,6-O-benzylidene-3-deoxy-3-C-diphenylarsino--D-altropyranoside [89], were synthesised via reaction of Ph2PLi or Ph2AsLi with p-tosyl, mesyl, epoxy or carbonyl substituted sugar reagents. Steric factors play a large part in determining the reactivity of the precursor sugars towards the phosphorous or arsenic n
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31

Trusty, Susan Eble 1957. "Carbohydrate metabolism in pot chrysanthemum." Thesis, The University of Arizona, 1990. http://hdl.handle.net/10150/291653.

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Studies were performed to determine the concentration of soluble carbohydrates and starch in chrysanthemum plants at various stages of vegetative and floral development. Leaves of pot chrysanthemum (Chrysanthemum morifolium 'Charm' or 'Favor') grown under full irradiance had more soluble carbohydrates and starch than those grown with 65% irradiance reduction. Both showed clear diurnal variation in carbohydrate concentrations. Inflorescences exhibited no diurnal fluctuations in total soluble carbohydrate (TSC). Sucrose was the only translocated carbohydrate in chrysanthemums in quantities detec
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32

Liang, Yi. "Carbohydrate Derivatives in Antibiotics Research." DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/298.

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In this study, we investigated the potential applications of carbohydrates in the development of new antibiotics. To tackle the problem of multidrug-resistant variants of M. tuberculosis (MDR-TB), we investigated the biosynthesis pathways of trehalose, which has contributed to significant drug resistance. Some new methods were developed for the synthesis of potential inhibitors (6-azido-trehalose and 6,6'-diazido-trehalose) that have been designed to imitate the intermediate molecule (trehalose 6-phosphate, TPP) of OtsA-OtsB pathway. At the same time, some new antibacterial agents based on tre
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33

Swaminathan, C. P. "Energetics Of Protein-Carbohydrate Recognition." Thesis, Indian Institute of Science, 2000. https://etd.iisc.ac.in/handle/2005/210.

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The work embodied in this thesis pertains to an attempt to understand better, the molecular basis of protein-carbohydrate recognition. For this purpose a systematic study was undertaken, not only of the energetics of lectin-sugar interactions, which serve as molecular recognition prototype of protein-carbohydrate interactions, but also of the complex effects of solvent water molecules surrounding both the species in solution state. The systems chosen for investigation include the specific recognition of sugars by lectins from diverse families, leguminosae and moraceae. The following salient as
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34

Swaminathan, C. P. "Energetics Of Protein-Carbohydrate Recognition." Thesis, Indian Institute of Science, 2000. http://hdl.handle.net/2005/210.

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The work embodied in this thesis pertains to an attempt to understand better, the molecular basis of protein-carbohydrate recognition. For this purpose a systematic study was undertaken, not only of the energetics of lectin-sugar interactions, which serve as molecular recognition prototype of protein-carbohydrate interactions, but also of the complex effects of solvent water molecules surrounding both the species in solution state. The systems chosen for investigation include the specific recognition of sugars by lectins from diverse families, leguminosae and moraceae. The following salient as
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35

Bengtson, Per. "Carbohydrate dependent adhesion of leukocytes and the role of fucosyltransferase VII /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/med762s.pdf.

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36

Vance, Denice A. "The Effects of Carbohydrate, Protein, and Carbohydrate with Protein Solutions on 200-Meter Sprint Speed." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/nutrition_theses/24.

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Purpose: To investigate the differential effects of solutions providing varying concentrations of carbohydrate and/or protein ingested between 200-meter sprints on sprint time. Subjects: Recruitment was from the Georgia State University track and field team. Methods: The study protocol was approved by the Georgia State University IRB. Ten subjects, 18 to 21 years of age, consented to be included in the study. Nine subjects (7 females; 2 males) completed trial 1, six subjects (5 females; 1 male) completed trial 2, and three subjects (2 females; 1 male) completed the final trial. Each trial co
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37

Bosch, Andrew Norman. "The effect of carbohydrate-loading and carbohydrate ingestion on fuel substrate kinetics during prolonged cycling." Doctoral thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/26557.

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It has been well established that both carbohydrate-loading before and carbohydrate ingestion during exercise can enhance endurance performance by supplying carbohydrate for oxidation. However, the precise mechanism(s) underlying the proposed ergogenic effects of these procedures remain to be established. The studies in this thesis were therefore designed to examine the effects of carbohydrate-loading and carbohydrate ingestion on fuel substrate kinetics.
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38

Tonelli, Devin L. "Small Molecule Ice Recrystallization Inhibitors and Their Use in Methane Clathrate Inhibition." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23994.

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Inhibiting the formation of ice is an essential process commercially, industrially, and medically. Compounds that work to stop the formation of ice have historically possessed drawbacks such as toxicity or prohibitively high active concentrations. One class of molecules, ice recrystallization inhibitors, work to reduce the damage caused by the combination of small ice crystals into larger ones. Recent advances made by the Ben lab have identified small molecule carbohydrate analogues that are highly active in the field of ice recrystallization and have potential in the cryopreservation of li
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39

Castilla, López Javier. "Carbohydrate manipulations towards high-mannose oligosaccharides." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/87113.

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L’objectiu d’estudi de la tesi és el desenvolupament de nous mètodes sintètics per a la l’obtenció d’oligosacàrids i tio-anàlegs mitjançant processos polimèrics d’obertura d’anell. Aquestes estructures es poden trobar en una gran varietat de productes naturals on formen part de substàncies biològicament actives. D’aquesta manera, s’han desenvolupen rutes sintètiques per l’obtenció de carbohidrats epóxidats, episulfurats, carbonatats i tiocarbonatats. Els monòmers sintetitzats han estat sotmesos a diferents reaccions d’oligomerització. Curiosament, la cerca de nous mètodes de síntesi d’epiti
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40

Street, Ian Philip. "Protein - carbohydrate interactions in glycogen phosphorylase." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25049.

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It has long been observed that some organo-fluorine compounds exhibit enhanced biological activity over their non-fluorinated precursors, however reasons for these unusual properties still remain poorly understood. An explanation which has been widely used relates to the ability of the C-F fragment of the analog to participate in hydrogen-bonding interactions with its protein receptor. For this reason, fluorinated carbohydrates have been used as hydrogen-bonding probes with a number of proteins. Thus there exists a need for a systematic investigation into the hydrogen-bonding ability of the C
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41

Otten, Lucienne. "Pathogen detection based on carbohydrate adhesion." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/77814/.

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The rapid detection of pathogenic organisms to ensure appropriate administration of treatment remains a global healthcare challenge. This is becoming increasingly difficult, as identification of the organism alone is no longer enough, with the rise of drug resistance amongst many pathogens it is becoming increasingly important that both the pathogen and drug resistance are identified. Currently, rapid identification can be achieved through a variety of techniques. However, many of these techniques are expensive, require extensive sample preparation, or highly trained personnel to run with resu
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42

Clayton, Helen. "Carbohydrate oxidation in maize bundle sheath." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335719.

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43

Pennington, J. E. "Carbohydrate differentiation antigens of the mouse." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355116.

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44

Emmerson, Daniel P. G. "Carbohydrate-derived ligands for asymmetric catalysis." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427869.

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45

Petchey, M. "Lens carbohydrate metabolism and cataract chemotherapy." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371562.

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46

Komsta, Zofia Aleksandra. "1,2-metallate rearrangement of carbohydrate derivatives." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.534826.

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47

Joshi, Gururaj G. "New water soluble synthetic carbohydrate receptors." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.557976.

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The macrotricyclic system as a receptor for carbohydrates in organic as well as aqueous media has been extensively studied within the Davis group. The hydrogen bonding and CH-π interactions are the two main non covalent interactions operating for the recognition of carbohydrates in our system. In principle higher affinities could be achieved by enhancing either of these types of interactions. The possibility of enhancing H-bonding interactions with host-guest was explored by the introduction of heterocyclic linkers in the 'temple' receptors. Macrocycle with pyrrole linker 132 and pyridine link
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48

Trimble, Esther R. "Carbohydrate-deficient transferrin and alcohol abuse." Thesis, Queen's University Belfast, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388195.

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49

Jones, Nigel Alan. "Synthesis of carbohydrate-based natural products." Thesis, University of East Anglia, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426420.

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50

Simpson, Peter James. "Structural studies of carbohydrate-binding modules." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322930.

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