Tesis sobre el tema "Biomedicine"
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Arnaudo, Elisa <1985>. "Biomedicine and pain". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5876/1/Arnaudo_Elisa_thesis.pdf.
Texto completoArnaudo, Elisa <1985>. "Biomedicine and pain". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5876/.
Texto completoMaggiori, Claudia. "Mathematical models in biomedicine". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21247/.
Texto completoSilva, Mônica Freitas da. "Engenharia de superfície de nanopartículas magnéticas para biomedicina: recobrimentos com macromoléculas visando estabilização e compatibilidade em meio fisiológico". Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/75/75134/tde-23042013-105323/.
Texto completoSuperparamagnetic iron oxides nanoparticles (SPION) have been highlighted in several areas of biotechnology and biomedicine, for example in cancer treatment, in labeling of cells and as contrast agent in magnetic resonance imaging (MRI). The purpose of this study was synthesizing SPION with intensified saturation magnetization by modified polyol process, and using surface agents to enhance the surface properties. Carboxymethildextran, metylpolietileneglycol, chitosan, silica and 3-aminopropyltrimethoxysilane (APTMS) were utilized as surface modifiers. By transmission electron microscopy (TEM), SPION showed narrow particle size distribution, with an average diameter around 5 nm. The X-ray diffraction studies indicated the formation of magnetite in all synthesized systems in which the modified polyol process was utilized. FTIR measurements showed the presence of vibration modes related to the macromolecules and inorganic compounds used to SPION surface modifications. TEM of the different surface modifications showed the agglomerate formation, which depends on the used surface modifier. SPION coated with APTMS was functionalized with folic acid, showing satisfactory results. However other characterization techniques will be necessary for study this modification. Quantity of free amine groups was determinate in the amount coated with APTMS for functionalization, and UV-Vis spectroscopy determinates a good result. Vibrating sample magnetometry (VSM) indicates similar behaviors in all cases against SPION without surface modifiers. These results suggest that the surface modifications were performed satisfactorily. Utilized methods for changing the hydrophobic to hydrophilic surface showed effectives, however, the quantity of surface modifiers should be better studied. Therefore, SPION functionalized with different hydrophilic surfaces were obtained, which possess high potential to be used as devices in biomedical applications.
Nyonator, John Paul. "Informal Knowledge and Biomedicine: Ghanaian Assemblages". Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28666.
Texto completoПлохута, Тетяна Миколаївна, Татьяна Николаевна Плохута, Tetiana Mykolaivna Plokhuta y O. V. Orel. "Application of magnetic nanoparticles in biomedicine". Thesis, Вид-во СумДУ, 2011. http://essuir.sumdu.edu.ua/handle/123456789/22727.
Texto completoMcCord, Jennifer Phipps. "Protein Engineering for Biomedicine and Beyond". Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/90787.
Texto completoDoctor of Philosophy
Many applications in medicine and research require molecular sensors that bind their target tightly and selectively, even in complex mixtures. Mammalian antibodies are the best-studied examples of these sensors, but problems with the stability, expense, and selectivity of these antibodies have led to the development of alternatives. In the search for better sensors, repeat proteins have emerged as one promising class, as repeat proteins are relatively simple to design while being able to bind specifically and selectively to their targets. However, a drawback of commonly used designed repeat proteins is that their targets are typically restricted to proteins, while many targets of biomedical interest are sugars, such as those that are responsible for blood types. Repeat proteins from the immune system, on the other hand, bind targets of many different types. We looked at the unusual immune system of a freshwater polyp as inspiration to design a new repeat protein to recognize nonprotein targets. My second research project focused on binding cellulose, as it is the most abundant and inexpensive source of biological matter and therefore is widely considered a possible source for liquid fuel. However, processing costs have kept cellulose-based fuels from competing commercially with biofuel made from corn and other starchy plants. One strategy to lower costs relies on using helper proteins to reduce the amount of enzyme needed to break down the cellulose, as enzymes are the most expensive part of processing. We designed such a protein for this function to be more stable than natural proteins currently used. The resulting designed protein binds to multiple cellulose structures. Designing a protein from scratch also allows us to study small changes to the binding site, allowing us to better understand how these proteins bind to different cellulose-based materials in nature and how to apply their use to industrial applications. Biomaterials made from natural human hair keratin have mechanical and biochemical properties that make them ideal for tissue engineering and wound healing applications. However, the process by which these proteins are extracted from hair leads to some protein degradation and brings with it byproducts from hair, which can cause unfavorable immune responses. Making these proteins synthetically allows us to have pure starting material, and lets us add new features to the proteins, which translates into materials better tailored for their applications. We discuss here one example, in which we added a cell-binding motif to a keratin protein sequence.
Dieninis, Žydrūnas. "Biomedicininės informacinės sistemos realizacija internete". Master's thesis, Lithuanian Academic Libraries Network (LABT), 2004. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2004~D_20040922_110909-16825.
Texto completoProkopyev, Oleg A. "Nonlinear integer optimization and applications in biomedicine". [Gainesville, Fla.] : University of Florida, 2006. http://purl.fcla.edu/fcla/etd/UFE0015226.
Texto completoBalinskiy, M., Тетяна Миколаївна Плохута, Татьяна Николаевна Плохута y Tetiana Mykolaivna Plokhuta. "Apatite-biopolymer materials and coatings for biomedicine". Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/77838.
Texto completoForsberg, Susann. "Ayurveda versus Biomedicine - Competition, Cooperation or Integration?" Thesis, Malmö högskola, Fakulteten för hälsa och samhälle (HS), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-26261.
Texto completoNon-communicable diseases [NCDs] are increasing in both developing and developed countries. Western medicine is not able to offer satisfying solutions and treatments for people suffering from NCDs. TM/CAM have shown promise of effectiveness in the prevention and treatment of NCDs and many people now turn to TM/CAM. Hence it is of great interest to investigate the possibilities of increased integration of TM/CAM in national health care systems. This study was carried out in Sri Lanka, with the aim to investigate the main forces promoting and obstructing cooperation and communication between practitioners of Ayurvedic, Western and traditional medicine, in order to see how this affects integration of the medical subsystems. The focus of this qualitative study was the “Outcome oriented, evidence informed Ayurvedic Community Health Promotion Program”; a collaboration project aiming to integrate Ayurveda and Western medicine in primary health care. Semi-structured interviews, participatory observation and document analysis were carried out during three months in Sri Lanka and the results were analysed using Paul Unschuld’s theory on structured competition, cooperation or integration. The results indicate that the overall coexistence of Ayurveda and Western medicine in Sri Lanka is structured competition, while the collaboration project is aiming for structured cooperation. The results further show that the Sri Lankan parallel political approach to integration can be argued to obstruct integration, while the regulation of Ayurvedic practitioners increases cooperation through professionalization. Education is a main influencing factor for cooperation; lack of CAM-knowledge in medical students obstructs cooperation while westernization of Ayurvedic doctors both promotes and obstructs cooperation and integration. Capacity building, research based on Ayurvedic fundamentals and keypersons with knowledge of both sectors are of importance for increased cooperation and integration to come about.
Rozinek, Michal. "Aplikace shlukové analýzy při zpracování biomedicínských dat". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218223.
Texto completoWainer, Rafael E. "Permeable bodies : children, cancer, and biomedicine in Argentina". Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/55636.
Texto completoArts, Faculty of
Anthropology, Department of
Graduate
Will, III Willard Wilson. "Making hospital chaplains in an age of biomedicine". Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=92199.
Texto completoI set out to accomplish several tasks with this work. First, I seek to broaden anthropological depictions of religion in biomedical settings, particularly those that present it as an eccentricity, weakly rational coping mechanism, psychopathology, and/or import from non-Western cultures. Second, I challenge interpretations of decision- and meaning-making in clinical settings that focus narrowly on biomedical practitioner/patient relations. I do this by analyzing narrative interactions between chaplains and patients in order to highlight the distinctive role of religious practitioners in reflexive and semiotic aspects of the inpatient experience. Third, I attempt to broaden anthropological understandings of the formation of religious leaders by examining processes of role ascription and role attainment in the face of a medical system that is increasingly hegemonic in its scope, both psychologically and morally. I do this through (1) a phenomenological analysis of residents' exposure to clinical difference and strangeness; (2) a thick description of their development of an altruistic, non-judgmental presence and their demarcation of therapeutically appropriate emotional, spiritual, and somatic boundaries; and (3) a typology of the ways in which the doctrine-experience dialectic leads to the gradual emergence of individual philosophies of pastoral care. Fourth, this research offers novel insights about solidarity and authority to the growing sub-discipline of the anthropology of Christianity, an emerging specialty which has shed light on social relationships in ecclesiastical and community settings, as well as on symbolic healing rituals, but has had relatively little to say about the role of religious specialists in healing vis-à-vis Western clinical science.
Dans cette thèse, j'explore la formation et le travail de résidents aumôniers (chaplain) dans un hôpital universitaire situé dans un grand centre urbain de l'Est des États-Unis. Je me base ici sur ma participation à un programme d'Éducation pastorale clinique (CPE), un apprentissage religieux unique sur le plan culturel, qui combine (1) un service pastoral sur des unités assignées avec des patients, des familles et le personnel médical, et (2) un travail de réflexion et d'analyse effectué au sein d'une petite cohorte d'étudiants placés sous la direction d'un superviseur-praticien d'expérience. J'utilise cette expérience à la fois comme un point de vue privilégié sur les questions de souffrance, de réflexivité et de corporéité, et comme une manière d'ouvrir sur une composante de l'entreprise thérapeutique encore largement négligée par ceux qui s'intéressent aux aspects sociaux et philosophiques de la médecine. fr
Ce travail se donne différents objectifs. D'abord, je vise à élargir la manière dont l'anthropologie se représente la place de la religion dans des contextes biomédicaux, en interpellant particulièrement les descriptions qui la présentent comme une excentricité, un moyen peu rationnel d'affronter les problèmes, un signe de psychopathologie et/ou quelque chose d'importé à partir de cultures non occidentales. En deuxième lieu, je questionne les interprétations des processus de décision et de recherche de sens en contexte clinique, qui se centrent de manière étroite sur les relations entre patients et praticiens biomédicaux. Je le fais à partir d'une analyse des interactions narratives entre aumôniers et patients, en vue de mettre en relief le rôle distinctif des praticiens religieux par rapport aux aspects réflexifs et sémiotiques de l'expérience de l'hospitalisation. En troisième lieu, je cherche à élargir les façons dont l'anthropologie approche la formation des leaders religieux, en examinant les processus d'assignation et d'acquisition de rôle face à un système médical qui se révèle de plus en plus hégémonique dans sa visée, à la fois psychologique et morale. Pour y arriver, je procède ici (1) à une analyse phénoménologique de l'exposition des résidents à la différence culturelle et à l'étrangeté; (2) à une description riche de la manière dont ils développent une présence altruiste et dépourvue de jugement et celle dont ils établissent des frontières appropriées sur les plans émotionnel, spirituel et somatique; (3) et à l'élaboration d'une typologie des façons dont la dialectique doctrine - expérience conduit à l'émergence graduelle de philosophies individuelles de service pastoral. En quatrième lieu, cette recherche offre de nouveaux éclairages sur les notions de solidarité et d'autonomie et contribue ainsi à un champ en expansion, celui de l'anthropologie de la chrétienté, une spécialité
Angel, K. "Psychosomatic histories and the causes of contemporary biomedicine". Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596124.
Texto completoLülf, Henning. "Zeolites as key-components for electronics and biomedicine". Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-01058578.
Texto completoRendell, Joanne. "Decoding AIDS biomedicine : the possibilities of writing suffering". Thesis, University of Sheffield, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251520.
Texto completoGuck, Jochen Reinhold. "Optical deformability micromechanics from cell research to biomedicine /". Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3037014.
Texto completoMadlock-Brown, Charisse Renee. "A framework for emerging topic detection in biomedicine". Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/1483.
Texto completoSenna, Regina Amélia de Magalhães. "Passagens de idade: uma análise antropológica sobre as articulações entre o saber biomédico e o saber leigo no discurso de mulheres de camadas médias". Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=5507.
Texto completoThis paper is designed to study the association between the biomedical knowledge and the lay knowledge in the discourse of the average urban female between 40 and 60 years of age in the city of Rio de Janeiro. It is based on the socio-anthropological production about gender, body, menopause and aging, and the analysis of the construction of the scientific fact as well. Today, there is an increasing prevalence of the biological discourse in determining what pertains to the female and to the male body, which is certainly crossed by gender relations. From a constructionist standpoint, it surveys the significance assigned by biomedicine to the role of the hormones, not only regarding the functioning and the regulation of the female body, but also regarding how women will live their daily life. Furthermore, it looks for clues with a view to the problematization of the power of certain dualities, like the biological versus the social. These dualities expose a form of binary hierarchical organization of thought so typical of our modern western society. The notion of network is an important mark-out for a better understanding of the background of the current knowledge with respect to the male and female physiological events. Despite the fluid and diversified quality of the subject under discussion, the intensity of the biomedical hormonal discourse can be strongly perceived in the accounts regarding the body and the life of the respondent females.
Pinho, Paula Andréa [UNIFESP]. "ITINERÁRIOS TERAPÊUTICOS EM CONSTRUÇÃO: Aids, Biomedicina e Religião". Universidade Federal de São Paulo (UNIFESP), 2010. http://repositorio.unifesp.br/handle/11600/9777.
Texto completoO texto que se segue é uma etnografia dos itinerários terapêuticos de pessoas com HIV/Aids. O objetivo é efetuar uma aproximação das relações entre saúde/doença e religião a partir da apreciação desses itinerários construídos e experienciados. A idéia que norteará o estudo é a de que, embora a biomedicina detenha o monopólio legitimado das soluções curativas referentes às questões de enfermidade, ela não se constitui como referência única para pensá-las. Por isso, admitindo a existência de numerosas terapias, intenta-se aqui mapear as articulações que se estabelecem entre as soluções biomédicas e religiosas no contexto da epidemia. A etnografia realizada no Centro de Referência em DST/Aids da cidade de São Paulo – centro que atende pacientes soropositivos – permitiu verificar itinerários complexos nas quais os sujeitos recorrem a diversas terapias e mesclam os tratamentos biomédicos oficiais a terapias religiosas. O empreendimento etnográfico procurou seguir essas trajetórias e verificar como essas pessoas representam, articulam e vivenciam essas terapias. Pondero que na acepção dos soropositivos ouvidos, a relação que se anuncia entre as categorias da doença e tratamento não separa a terapia biomédica da religiosa: ao invés disso, foi possível observar um continuum entre as duas práticas curativas. E aqueles que por elas circulam promovem a articulação dos universos simbólicos de cada qual, compondo-os em seu itinerário terapêutico sempre passível de transformação.
The following text is an ethnography of the therapeutic itineraries of people with HIV/Aids. The goal is to make an approximation of the relationship between health/illness and religion, from the assessment of therapeutic constructed and experienced. The idea that guides the study is that, although biomedicine holds the legitimate monopoly of therapeutic solutions, it does not constitute a single reference for thinking about them. Therefore, assuming the existence of numerous therapies, the objective is to map the joints that are established between the biomedical and religious solutions in context of the epidemic. The ethnography at the Centro de Referência e Treinamento in STD/Aids in São Paulo – a center that serves HIV-infected patients – has shown complex itineraries in which the subjects use a range of therapies and blend biomedical treatments and religious therapies. The ethnographic enterprise tried to follow these paths and verify how these people represent, articulate and experience these therapies. For the patients from this study, the relationship announced between the categories of disease and treatment does not separate the religious and biomedical therapies: instead, it was observed a continuum between the two healing practices. And those who circulate among them by promoting the articulation of their symbols make them in their therapeutic itinerary always suitable for further transformation.
TEDE
Angel, Katherine. "Causality and psychosomatic histories in contemporary Anglo-American biomedicine". Thesis, University of Cambridge, 2008. https://www.repository.cam.ac.uk/handle/1810/252110.
Texto completoLippincott, Thomas. "Unsupervised approaches to syntactic verb frame acquisition for biomedicine". Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708513.
Texto completoDi, Fede Corella Ann. "Bio-logics of bodily transformation| Biomedicine and makeover TV". Thesis, University of California, Irvine, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10246999.
Texto completoThis dissertation began as an attempt to understand how biomedical concepts and practices, which undermine the salience of norms drawn from the ?natural order? are relayed through mass media and inform self-understanding, social being, self-care, and practices of everyday life. The project tracks makeover TV?s valorization of the metamorphic or transformative body as an ideal that emerges through, and across, various contexts in science and popular culture. This genre of programming is one of the few sites at which the aesthetics of biotechnology are made visible in non-fiction representations and are depicted as part of everyday life. Each of this dissertation?s televisual case studies is exemplary of how popular culture absorbs and makes visible ideas from biomedicine, and how this relates to public policy, economic conditions, and developments in biomedicine. Harnessing biomedicine has aided in television?s recreation of itself as an essential element of ?new? media. It has done so by presenting itself as a technology for managed health care at a distance, and by presenting the body as a primary medium of self-expression. Television encourages ideas about the body as ?transmedial continuity? or form of media, both physical and symbolic, represented through and across variable sites, objects and platforms. Under the aegis of ?health,? medical makeover programs establish a direct relationship between body-based visual identity and life, promote biomedicine as a ubiquitous means of conceiving of the self and body, and posit biotechnology as a tool for transformation and self-care. In this context, health becomes a visual ideal and an organizing principle for self-care, which are framed as prerequisites for social, economic, and political legibility. Although biomedicine challenges essentialist models of ?natural order? through which misogynist and racist norms have been justified in modern culture, its appearances in narratives of self-transformation are overwhelmingly framed by politically retrogressive ideals of embodiment, which it aids in achieving. Given the pervasiveness of visual media and its centrality in refiguring norms that have social, biological and political significance, media literacy and critical acuity are crucial to preserving both cultural and bio diversity.
Rafailov, Ilya. "The development of novel photonics based techniques for biomedicine". Thesis, Aston University, 2017. http://publications.aston.ac.uk/33423/.
Texto completoGuidotti, Giulia <1989>. "Design of new biopolymers for biomedicine and food-packaging". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/8892/2/Guidotti_Giulia_Tesi.pdf.
Texto completoMagro, Massimiliano. "Development of novel nanotechnologies in food, water and biomedicine". Doctoral thesis, Università degli studi di Padova, 2020. http://hdl.handle.net/11577/3425775.
Texto completoFuentes, Sempere Isabel. "Aplicaciones de los metalacarboranos en el campo de la biomedicina y de la energía". Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/667896.
Texto completoThe work presented in this thesis has been focused mainly on the use of metallacarboranes in different applications in the field of biomedicine and energy. The thesis has been divided in 5 chapters. The first chapter explains the different types of boron clusters (boranes, carboranes and metallacarboranes) and the most important properties (self-assembly and redox properties) and applications (biomedicine, materials science and energy) of metallacarboranes to understand the research done in the thesis. The second and third chapters are related to the use of metallacarboranes in different bioapplications. The research done in the second chapter is divided in three parts: 1) the study of interaction between DNA and the metallacarboranes Na[COSANE], Na[FESANE] and Na[Cl6-FESANE] using the techniques: melting curve, circular dichroism, UV-Visible, DLS, Cryo-TEM, TEM, IR, raman and optical microscope. 2) The study of the cellular viability, the cellular uptake and distribution of Na[COSANE] in glioblastoma U87 and melanoma A375 cells, the cellular uptake and distribution of boron in horse blood and the biodistribution of boron in normal mice. And 3) the study of Na[FESANE] and Na[Cl6-FESANE] as redox mediators in DNA sensors to detect mutations. And the research done in the third chapter is divided in two parts: 1) the study of interaction between BSA and the metallacarborane Na[COSANE] using the techniques: DLS, TEM, RMN, circular dichroism, fluorescence, ξ-potential, IR, SEM-EDX and elemental analysis. And 2) the study of the stability of BSA in presence and absence of Na[COSANE] upon thermal and chemical induced denaturation. The fourth and fifth chapters are related to the use of metallacarboranes in different energy applications. The research done in the fourth chapter is divided in two parts: 1) the study of the physicochemical and thermal properties and the ionic conductivity of the polymer PBI doped with different salts of metallacarboranes and tetraphenylborate to be used in fuel cells and batteries. And 2) the study of electrochemical properties (specific capacitance and overoxidation limit resistance), SEM-EDX, electrical conductivity and thermal properties of the polymer PEDOT doped with different salts and derivatives of metallacarboranes to be used in supercapacitors. And the research done in the last chapter is mainly focused on the use of the metallacarborane Na[Cl4-COSANE] as additive in YP50F commercial activated carbon in asymmetric aqueous supercapacitor to enhance the stability.
Jess, Phillip Ronald Thomas. "Advanced techniques in Raman tweezers microspectroscopy for applications in biomedicine /". St Andrews, 2007. http://hdl.handle.net/10023/410.
Texto completoRobertson, William J. "Queering biomedicine| Culture and (in)visibility in a medical school". Thesis, The University of Texas at San Antonio, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1545332.
Texto completoWhat can the experiences of queer medical students tell us about the existence of homophobia and heteronormativity in medical environments? This thesis focuses on the experiences of queer medical students and physicians as they are enculturated into biomedical theory and practice. I begin by laying out the historical and theoretical trends in the study of sex/gender and sexuality, with a particular focus on how these trends have affected the anthropological study of sex/gender and sexuality. Next, I review the literature on queer health and medical education in order to situate the results of the research within the broader medical education and queer health disparities literatures. After detailing the methods used to gather and analyze the data that makes up this thesis, I explore my informants' experiences with their medical education and training with particular focus on medical case studies as an example of the ways that heteronormativity becomes internalized by informants in medical environments. Next, I examine the interaction between my informants' ideas about (in)visibility in medical environments, and I introduce the concept of the irrelevance narrative as a means of making sense of how informants view the role of their queerness in their practice of medicine. I conclude with a discussion of the limitations of this research and provide a list of best practices for medical education, training, and practice on queer health issues informed by the literature and my discussions with informants.
Jess, Phillip R. T. "Advanced techniques in Raman tweezers microspectroscopy for applications in biomedicine". Thesis, University of St Andrews, 2007. http://hdl.handle.net/10023/410.
Texto completoMills, Elizabeth Anne. "Embodied precarity : the biopolitics of AIDS biomedicine in South Africa". Thesis, University of Sussex, 2014. http://sro.sussex.ac.uk/id/eprint/48911/.
Texto completoSmus, Justyna Paulina. "Application of enhanced Raman techniques in life sciences and biomedicine". Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/409721/.
Texto completoKielar, Charlotte [Verfasser]. "DNA origami nanostructures in biomedicine: Beyond drug delivery / Charlotte Kielar". Paderborn : Universitätsbibliothek, 2020. http://d-nb.info/1215177186/34.
Texto completoZaballos, Samper Alejandro. "La molecularización del estrés crónico. El ciudadano VIH como proceso de subjetivación contemporáneo". Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/666056.
Texto completoOver past four decades there has been a mutation of medicine as scientific knowledge that addresses to an intense and novel interest for the biological basis of vital phenomena, based on new procedures in laboratory and clinic practices and the progressive realignment between biology and medicine, namely Biomedicine. From a qualitative methodological approach to the HIV (Human Immunodeficiency Virus) epidemic and taking STS (science and technology studies) and CMH (Critical Medical Humanities) elements, this Thesis explores HIV materiality and analyses the formation of a (bio)citizenship distinctive of contemporary Western society: the HIV chronic citizen, as a case of life´s government biomedicalization. Considering a new ontology of health and vital organisms, a reflection is made about the new findings on the HIV field, which point out a direct link between health, psychological stress and Interleukins-6, a sort of immune system cells that promote the chronic inflammation which defines currently HIV. It is from these new approaches between health and stress, between the social and the molecular, that the processes of subjectivation that transcend the biological understanding of existence will be here considered.
Wikman, Maria. "Rational and combinatorial protein engineering for vaccine delivery and drug targeting". Doctoral thesis, Stockholm : Department of Biotechnology, Royal Insitute of Technology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-231.
Texto completoNordberg, Erika. "EGFR and HER2 Targeting for Radionuclide-Based Imaging and Therapy : Preclinical Studies". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8721.
Texto completoGellein, Kristin. "High resolution inductively coupled plasma mass spectrometry: Some applications in biomedicine". Doctoral thesis, Norwegian University of Science and Technology, Department of Chemistry, 2008. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2233.
Texto completoEven though trace elements are present at minute amounts in the human body, they have a considerable impact on human health, either as essential elements in biochemical functions indispensable for life, or on the contrary, interfering with vital processes. Knowledge of the optimal concentrations of trace elements in the human body is therefore of great importance. Since the first systematic determinations of trace elements in human body fluids started in the 1940s there has been an incredible development in analytical instrumentation. The objective of this thesis is to demonstrate successful applications of HR-ICP-MS (high resolution inductively coupled plasma mass spectrometry) in biomedicine.
Research on trace elements in humans is challenging because of very low levels and many different types of matrices. The first important issue regarding trace element analysis is sampling and sample storage. It is essential to control all possible sources of contamination and other factors that can influence the concentrations. Preservation of biological samples is often required, and effects of the frequently used preservation and storage of biological tissue in formalin have been examined in this work. The concentrations of 20 trace elements were determined in formalin where brain samples had been stored at different time intervals ranging from few weeks to several years. The results show that storage of biological tissue in formalin may result in losses of trace elements from the tissue to the formalin, and that the leakage is time-dependent. This emphasizes the importance of controlling all steps from sample collection to analysis.
With its low detection limits, high resolution and multielement capability, HR-ICP-MS offers a considerable potential for further understanding the role of trace elements in biological material. These features were used to develop a method to study protein-bound metals in cerebrospinal fluid (CSF). CSF samples from eight healthy persons were separated by size exclusion HPLC and the resulting fractions were analyzed using HR-ICPMS. The major challenge in this work was the very low concentrations as only 100 μl CSF was injected to the column resulting in 35 fractions of 0.75 ml. It was possible to determine more than 10 elements of clinical interest in the CSF fractions and the method provides an opportunity to study MT and other metal binding proteins in CSF.
Further, the potential to study exposure and intake of trace elements by HRICP- MS was explored by analyzing hair strands of five occupationally unexposed subjects. The trace element profiles of single hair strands were determined by analyzing 1 cm long segments. The challenge in this study was again the extremely small sample size, as the samples had an average weight of 0.05 mg. It was possible however to obtain results for 12 elements in these minute samples and valuable information about intake and exposure for Hg, Se and Sr was obtained.
HR-ICP-MS has the potential to be an excellent tool for obtaining information about disease development and progress. A rare and relatively unexplored neurodegenerative disease (Skogholt’s disease) was studied. The trace element concentrations in whole blood, plasma and CSF were determined in Skogholt patients, multiple sclerosis patients and controls. Increased levels of Cu, Fe, Zn, Se and S in CSF were found in CSF from Skogholt patients. These increased levels were not reflected in blood, and it is quite obvious that the increased levels are not caused by increased environmental exposure. The results suggest that the increased levels of these elements in CSF are due to a leakage of metal binding proteins from blood to the CSF.
Trace elements have been implicated in the development of Parkinson’s disease (PD), and a study was performed on trace elements in serum from Parkinson patients collected in 1995-97, 4-12 years before they were diagnosed with the disease. New samples from more than half of these patients were collected in 2007. No significant differences were found between preclinical levels and controls, except for a lower level of Hg in the patient group. However, when trace element serum levels in patients from before and after they were diagnosed were compared, significant differences for several elements were found. This suggests that trace element imbalances found in PD patients may be a result of disease development rather than a causal factor.
HR-ICP-MS offers a considerable potential for further understanding the role of trace elements in humans. Biological material is often available for analysis only in small amounts. HR-ICP-MS gives the opportunity of simultaneous quantification of many trace elements even in very small samples and with very low detection limits. This promotes new research in the field of trace elements in biological material. HR-ICP-MS also reduces the time and cost per analysis and broadens the amount of information available from a single specimen.
Paper II,III and V are reprinted with kind permission from Elsevier, sciencedirect.com
Lander, Bryn. "Mapping interorganisational collaboration within biomedicine : collaboration in infection and immunity research". Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44837.
Texto completoChaiyaratana, Nachol. "Neuro-genetic based hybrid frameworks with applications in biomedicine and robotics". Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298963.
Texto completoNelson, Tayler L. "Biomedicine, "Body-Writing," and Identity Management: The Case of Christian Science". Thesis, Boston College, 2011. http://hdl.handle.net/2345/1835.
Texto completoBiomedicine has become a gatekeeper to numerous social opportunities and has gained power through the ritual inscription of individual bodies. Bodies serve as intermediaries between personal identities and biomedicine; individuals can reclaim bodies as sites of "identity projects" (Giddens 1991) to resist biomedical power. This project examines the intersection of the societal preoccupations with biomedicine, bodies, and identity through the lens of the religious and healing tradition of Christian Science. Christian Science theologically rejects biomedicine in favor of spiritual healing treatment. Christian Science is an especially appropriate venue for exploring relationships between biomedicine, bodies, and identities because its teachings require not only belief in the ineffectiveness of biomedicine but also embodied resistance to it. Drawing on the work of Foucault (1977), Giddens (1991), and Frank (1995) and using information gleaned from semi-structured interviews--averaging 1.5 hours in length--with 12 Christian Scientists, I argue that Christian Scientists use religious identities to (1) evade biomedical risk society, (2) resist external authority and reclaim bodies as sites of knowledge and power, and (3) build spiritual community
Thesis (MA) — Boston College, 2011
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Sociology
Rolfsnes, Hans O. "Sonoptics : applications of light and sound in the context of biomedicine". Thesis, University of Dundee, 2011. https://discovery.dundee.ac.uk/en/studentTheses/d4619c09-a1c5-4fc0-86f6-a1b95ff6b6a8.
Texto completoMcReynolds, Naomi. "Advanced multimodal methods in biomedicine : Raman spectroscopy and digital holographic microscopy". Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/12129.
Texto completoTabi, Chama-James Tabenyang. "An investigation into the role of Traditional medicine in an era of biomedicine: Case of Qokolweni Location (KSDM), Eastern Cape, Republic of South Africa". Thesis, Walter Sisulu University, 2011. http://hdl.handle.net/11260/d1007165.
Texto completoGranville, Gillian. "Developing a mature identity : a feminist exploration of the meaning of menopause". Thesis, Keele University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327699.
Texto completoStoltsz, Werner Heinrich. "Comparison of resting state functional networks in HIV infected and uninfected children at age 9 years". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29582.
Texto completoThompson, Seth Mkhanyisi. "Optimisation of insertion point during latissimus dorsi tendon transfer". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29524.
Texto completoBohl, Kullberg Erika. "Tumor Cell Targeting of Stabilized Liposome Conjugates : Experimental studies using boronated DNA-binding agents". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3435.
Texto completoMirasol, Sofia Paulo. "Optoelectronic properties of Quantum Dots for biomedicine and energy-to-light conversion". Doctoral thesis, Universitat Rovira i Virgili, 2019. http://hdl.handle.net/10803/668348.
Texto completoEn la última década, la nanociencia se ha convertido en una tecnología novedosa debido a su versatilidad para ser empleada en muchas áreas de investigación. Uno de los nanomateriales más prometedores, los puntos cuánticos coloidales, han sido estudiados en profundidad por su extraordinario optoelectrónico y su versatilidad para usar en diferentes campos. La presente tesis se centra en la síntesis de diferentes puntos cuánticos, así como su uso en LED, células solares de perovskita y biosensores. Se han sintetizado tres puntos cuánticos diferentes: cadmio, perovskita y puntos cuánticos de carbono. Los dos primeros materiales presentan un alto rendimiento cuántico y banda de emisión estrecha. Sin embargo, su alta toxicidad es una inconveniente que se tiene que tener en cuenta. Como alternativa a su uso, sintetizamos puntos cuánticos de carbono. Su baja toxicidad y su biocompatibilidad es una buena alternativa a los nanomateriales que contienen metales pesados. Además, el material a base de carbono se puede preparar utilizando productos de uso diario como azúcar o jugo de naranja y se puede resolver en solventes que no sean de cloro, como etanol o agua. El trabajo presentado en esta tesis se llevó a cabo en el Instituto de Investigación Química de Cataluña (ICIQ) y en Eurecat, el centro tecnológico de Cataluña, entre marzo de 2015 y marzo de 2019.
In the last decades, nanoscience has emerged as a novel technology due to its versatility to be employed in many research areas. One of the most promising nanomaterials, colloidal quantum dots have been deeply studied for their extraordinary optoelectronic properties and their versatility in order to use in different fields. The present thesis is focused on the synthesis of different quantum dots as well as their use in LEDs, perovskites solar cells and biosensors. Three different Quantum Dots have been synthetized: cadmium, perovskites and carbon based quantum dots. The first two material present a high quantum yield and narrow emission band. However, their high toxicity is an important drawback. In order to avoid the use of those material we synthetized carbon quantum dots. Their low toxicity and biocompatibility is a good alternative to heavy metal-containing nanomaterials. In addition, carbon based material can be prepared using ordinary products as glucose or sucrose and solved in non-chloro solvents such as ethanol or water. The work discussed in this thesis was carried out at Institute of Chemical Research of Catalonia (ICIQ) and Eurecat the technological center of Catalonia, between March 2015 and March 2019.
Beißwanger, Anna Elena [Verfasser] y Heiner [Akademischer Betreuer] Stuckenschmidt. "Developing Ontological Background Knowledge for Biomedicine / Anna Elena Beißwanger. Betreuer: Heiner Stuckenschmidt". Mannheim : Universitätsbibliothek Mannheim, 2013. http://d-nb.info/1045153125/34.
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