Literatura académica sobre el tema "Biological assessment"

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Artículos de revistas sobre el tema "Biological assessment"

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Kukletová, I. y P. Buchta. "Façade biological colonisation assessment". IOP Conference Series: Materials Science and Engineering 379 (junio de 2018): 012035. http://dx.doi.org/10.1088/1757-899x/379/1/012035.

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Akhmatullina, N. B. y Sh A. Beisembayeva. "Biological dosimetry and unbiased assessment of detrimental radiation effect on humans". International Journal of Biology and Chemistry 7, n.º 2 (2014): 11–15. http://dx.doi.org/10.26577/2218-7979-2014-7-2-11-15.

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McIntyre, A. D. "Biological Effects and Pollution Assessment". Water Science and Technology 18, n.º 4-5 (1 de abril de 1986): 155–60. http://dx.doi.org/10.2166/wst.1986.0191.

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Techniques for studying biological effects of pollution in the sea are briefly reviewed and the circumstances under which they are most useful in coastal waters considered. Some approaches are particularly suitable for studying pollution hot spots, others for detecting low levels of contamination. The role of the scientist in pollution assessment is discussed and the problems caused by lack of ecological understanding highlighted.
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Goldstein, Bernard D. "Biological Markers and Risk Assessment". Drug Metabolism Reviews 28, n.º 1-2 (enero de 1996): 225–33. http://dx.doi.org/10.3109/03602539608994002.

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Kikkawa, Jiro. "Biological conservation, monitoring and assessment". Pacific Conservation Biology 1, n.º 4 (1994): 373. http://dx.doi.org/10.1071/pc940373.

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Of the three books Ian Spellerberg published from his broad experience in biological monitoring and conservation, Biological Conservation, co-authored by Stev� Hardes, is the most elementary, dealing with practical conservation in concise form. It is published in the Biology in Focus series to supplement mainstream textbooks for senior biology students.
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VEECK, LUCINDA L. "Oocyte Assessment and Biological Performance". Annals of the New York Academy of Sciences 541, n.º 1 In Vitro Fert (octubre de 1988): 259–74. http://dx.doi.org/10.1111/j.1749-6632.1988.tb22263.x.

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Hughes, I. A., Y. Morel, K. McElreavey y A. Rogol. "Biological assessment of abnormal genitalia". Journal of Pediatric Urology 8, n.º 6 (diciembre de 2012): 592–96. http://dx.doi.org/10.1016/j.jpurol.2012.10.002.

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Delignette-Muller, M. L. y L. Rosso. "Biological variability and exposure assessment". International Journal of Food Microbiology 58, n.º 3 (julio de 2000): 203–12. http://dx.doi.org/10.1016/s0168-1605(00)00274-9.

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Dewhurst, Ian C. "Toxicological assessment of biological pesticides". Toxicology Letters 120, n.º 1-3 (marzo de 2001): 67–72. http://dx.doi.org/10.1016/s0378-4274(01)00308-3.

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Brown, Timothy T., Joshua M. Kuperman, Yoonho Chung, Matthew Erhart, Connor McCabe, Donald J. Hagler, Vijay K. Venkatraman et al. "Neuroanatomical Assessment of Biological Maturity". Current Biology 22, n.º 18 (septiembre de 2012): 1693–98. http://dx.doi.org/10.1016/j.cub.2012.07.002.

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Tesis sobre el tema "Biological assessment"

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Jones, Robin C. "Modeling to Improve Vegetation-Based Wetland Biological Assessment". DigitalCommons@USU, 2014. https://digitalcommons.usu.edu/etd/2082.

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To meet the requirements of the Clean Water Act (1972), natural resource managers need to be able to detect biological degradation in wetland ecosystems. Biological indices are commonly used by managers to assess wetland biological condition. The accuracy and precision of wetland condition assessments are directly related to the performance of these indices, and biological index performance is thought to be related to how well an index controls for the effects of environmental attributes on biological assemblages. Many plant-based biological indices control for environmental and biological variation through the use of classification schemes that are based on geographic location and dominant vegetation type. However, the use of classification schemes tends to produce indices with limited applicability and may not adequately control for natural variation. The goal of my research was to use modeling techniques, as an alternative to classification, to account for biological variation associated with natural environmental gradients and to improve the performance of previously developed indices. I developed two types of model-based biological indices to quantify the biological condition of Ohio wetlands: a vegetation-based index of biological integrity (MVIBI) based on several attributes of wetland plant assemblages, and several indices of plant assemblage taxonomic completeness. I evaluated the accuracy and precision of the MVIBI relative to previously developed indices, and determined that the use of modeling techniques can significantly improve the performance of plant-based indices of biological integrity. Due to increases in accuracy and precision, use of the MVIBI should improve manager’s confidence in wetland biological condition assessments. The indices of taxonomic completeness exhibited poor performance relative to similar indices developed for other types of biological assemblages (i.e. aquatic insects, fish). I attribute poor index performance to my inability to accurately predict individual species occurrence, which is likely a result of plant communities being heavily structured by random disturbance events and biotic interactions that are difficult to account for. My results should help inform index developers of ways to potentially improve wetland condition assessment indices.
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Schultz, Timothy Paul. "Biopolitik a practical assessment of future biowarfare /". CLICK HERE TO VIEW:, 2004. https://research.maxwell.af.mil/papers/ay2004/ari/schultz.pdf.

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Kwan, Cheuk Hung. "Biosensors for biological nutrient monitoring /". View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?AMCE%202004%20KWAN.

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Peters, Carolyn J. Rhodes Dent. "An assessment template for introductory college biological laboratory manuals". Normal, Ill. : Illinois State University, 2006. http://proquest.umi.com/pqdweb?index=0&did=1225152531&SrchMode=1&sid=1&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1178116677&clientId=43838.

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Thesis (Ed. D.)--Illinois State University, 2006.
Title from title page screen, viewed on May 2, 2007. Dissertation Committee: Dent Rhodes (chair), Nada Chang, Kenneth Jerich, Marilyn Morey. Includes bibliographical references (leaves 107-113) and abstract. Also available in print.
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Widestrand, Johan. "Assessment of trichothecene contamination : chemical aspects and biological methodology /". Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2001. http://epsilon.slu.se/avh/2001/91-576-5808-0.pdf.

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Tidbury, Louise. "Development and biological assessment of prednisolone solid drug nanoparticles". Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3016766/.

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Zivich, Jamie Dionne. "Biological Health Assessment of an Industrial Wastewater Treatment Facility". Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/43523.

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The biological treatment of wastewaters from an industry was studied. Among the more important wastewater constituents of concern were high levels of suspended solids, due to graphite and nitrocellulose, the solvents, ethanol and acetone, and nitroglycerine (NG). The goal of this project was divided into four objectives. The impacts of graphite on a microbial population were evaluated. Sequencing batch reactors (SBRs) were used to monitor the effects of graphite on mixed liquor suspended solids (MLSS), removal of soluble chemical oxygen demand (sCOD), and specific oxygen uptake rates (sOUR). Graphite appeared to have no adverse effect on the microbes. The potential benefits of adding sucrose, nitrogen, and phosphorus to SBRs were evaluated. The MLSS was maintained at 1,250 mg/L, similar to the microbial population in the suspended growth system at the industry. Sucrose addition increased the sCOD removals and sOUR. No direct effect was observed with the addition of nitrogen and phosphorus. The treatability of acetone and ethanol was studied through sOUR and batch testing to determine bacterial response to solvents. Both solvents were utilized by the microbes. The concentrations tested proved to be beneficial, not inhibitory. Ethanol and a 50/50 mixture of acetone and ethanol were more viable substrates than acetone. NG treatability was examined under anoxic and aerobic conditions in SBRs and batch biological reactors. NG degradation occurred under anoxic conditions, but was more favorable in aerobic environments. NG was degraded in all SBR tests to below detection limit (0.5 mg/L); therefore, the optimal treatment could not be determined.
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McKinlay, Rebecca. "Risk assessment of endocrine disrupting pesticides in biological systems". Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/5585.

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Endocrine Disrupting Chemicals (EDCs) are a diverse array of natural and manmade substances capable of interfering with hormonally mediated processes. They are particularly harmful to cells that are differentiating and dividing rapidly, can stimulate unwanted cell growth, and can interfere with normal epigenetic imprinting causing changes that in some instances are heritable. Due to their epigenetic effects and effects on tissue growth and development, organisms at certain life stages are more vulnerable than others and effects may manifest a long time after exposure. The risks posed to human and environmental health by these compounds are currently unknown, but there is a growing scientific consensus that precautionary measures and further research to understand and quantify these risks are needed. Endocrine Disrupting pesticides represent a subset of EDC capable of reaching humans from a diverse range of sources via many different exposure routes. No definitive lists or screening methodologies exist to identify them. In the UK, exposure routes involving occupational pesticide use for agricultural purposes or the residues of these pesticides in food and water are well quantified but other sources of exposure are not. If risk management measures are to be enacted to protect the population, these exposures will have to be quantified and the risks they pose assessed. This project aims to identify the hazards posed by ED pesticides to humans living in the UK, prepare a framework for the assessment and management of risks they pose, identify the tasks that remain to be completed before such a framework could be implemented, and to investigate poorly documented ED pesticide exposure sources. Current toxicological testing of pesticides was found to be inadequate. Properties frequently exhibited by EDCs, such as non-monotonic (j-type) dose responses and the additive and synergistic actions of compounds were not taken into account. Only active ingredients are legally required to be tested even although adjuvants used to improve formulation effectiveness are not always inert and formulations can be more toxic or have greater ED potential than their active ingredients alone. Adjuvants are assessed on a reactive basis, which is not adequate to protect public health. A tiered risk assessment and management framework capable of screening potential ED pesticides and making recommendations for risk management can be created using existing deterministic and probabilistic models of human pesticide exposure. The identification of critical groups that are more vulnerable than the general population to the effects of EDCs allows risk assessment and management to be tailored to protect these groups, allowing the risk to both these groups and the general population to be minimised, in keeping with the precautionary principle. Further work is required, however, to collect appropriate datasets to model non agricultural exposure routes and model the exposure of rural residents and bystanders. Assumptions made in the creation of foreign models would need to be checked to ensure they were compatible with UK conditions. Appropriate ADIs for EDCs showing non-monotonic dose responses would also need to be determined, and exposure profile differences between people living in urban, periurban and rural environments would also have to be taken into account. A number of ED pesticides used for medicinal, veterinary and domestic purposes and the municipal and commercial maintenance of infrastructure and recreational areas were identified. Unfortunately little could be determined about the factors influencing their use by the public. The number of years spent in secondary education correlated positively with non ED medicinal pesticide use and both ED and non ED veterinary and domestic use. It was unclear why this should be. Golf courses were the most heavily treated publicly accessible areas studied and used the most ED pesticides. Large parks received least, with pesticide use concentrated on hard surfaces and high maintenance ornamental areas. Pesticide use in parks is dominated by herbicides. Applications to pavements and other publicly accessible hard surfaces consisted almost entirely of glyphosate based herbicides. Herbicide applications on pavements and in parks mostly take place in the spring and early summer. The bulk of pesticide applications on golf courses were applied in the autumn. Contractors carrying out maintenance work for local authorities were found to use more pesticides than local authority employees. Non chemical methods of ectoparasite, pest and weed prevention and control have the potential to reduce pesticide use. Some of the methods currently in use, however, were found to be more costly and challenging to implement than chemical methods. The integration of these into parasite, pest and weed prevention and control strategies where possible and their further should be encouraged.
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Woolley, Megan Rose. "Taxonomic and palaeobiological assessment of the South African mosasaurids". Master's thesis, Faculty of Science, 2021. http://hdl.handle.net/11427/33983.

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South African mosasaur remains consist of a frontal with articulating portions of the parietal and postorbitofrontals (SAM-PK-5265); two dentary fragments (SAM-PK-5265) assigned to ‘Tylosaurus capensis' by Broom in 1912 (SAM-PK-5265); an undescribed muzzle unit and associated isolated teeth (CGP/1/2265) from Pondoland and a more recently discovered isolated partial vertebra from St Lucia. Some research has been done on the material, but there is still uncertainty concerning their relationships and taxonomy. This research aims to provide a taxonomic assessment of all the SA mosasaurid material to better understand their phylogenetic relationships and to place them in the context of mosasaurs from other parts of Africa and globally. In addition, isotopic analyses, micro-computed tomography (micro-CT), mineralised tissue histology and scanning electron microscopy (SEM) are applied to the SA mosasaur remains to decipher various aspects of their palaeobiology. This study identifies three mosasaur taxa from SA: Mosasaurus sp., cf. M. hoffmannii., cf. Taniwhasaurus, and cf. Prognathodon. The isolated vertebra is assigned to Mosasaurus sp., cf. M. hoffmannii. The frontal and dentary fragments (SAM-PK-5265) originally described as Tylosaurus appears to be a mix of two taxa: One of the dentary fragments possesses replacement teeth with enamel ornamentation that resembles, Ta. mikasaensis, but is tentatively assigned to cf. Taniwhasaurus based on tooth recurvature. The other dentary fragment and a frontal with articulated elements are suggested to belong to the same individual as the muzzle unit for which the suggested assignment is cf. Prognathodon. Strontium analysis of tooth enamel dated the cf. Prognathodon material to the end of the Maastrichtian (87Sr/86Sr = 0.707817; age = 66.85Ma). The cf. Taniwhasaurus dentary fragment is likely Santonian-aged, as originally indicated in 1901. SEM of enamel from cf. Prognathodon reveals a complex array of prismless enamel types and pervasive aggregations of fossilised bacteria in the underlying dentine. The δ18OPO4 derived body temperature estimate (Tb) of the cf. Prognathodon (Tb = 33.21°C) compares well with previously reported Tb for mosasaurs and may indicate that the mosasaur was capable of maintaining a Tb higher than that of the surrounding seawater.
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Brickley, M. y Jo Buckberry. "Undertaking sex assessment". CIFA, 2018. http://hdl.handle.net/10454/17520.

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Libros sobre el tema "Biological assessment"

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Parachini, John. Combating terrorism: Assessing the threat of biological terrorism. Santa Monica, CA: RAND, 2001.

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Plotnikoff, R. W. Instream biological assessment monitoring protocols: Benthic macroinvertebrates. Olympia, WA: Washington Department of Ecology, 1994.

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Bode, Robert W. Methods for rapid biological assessment of streams. Albany, N.Y: Stream Biomonitoring Unit, Bureau of Monitoring and Assessment, Division of Water, NYS Dept. of Environmental Conservation, 1988.

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Plotnikoff, Robert W. 1995 ambient biological assessment monitoring implementation plan. Olympia, WA: Washington State Dept. of Ecology, 1995.

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Krewski, D. y D. B. Clayson. Toxicological risk assessment: Biological and statistical criteria. Boca Raton, Florida: CRC Press, 1985.

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McGill, Brian J. y Anne E. Magurran. Biological diversity: Frontiers in measurement and assessment. Oxford: Oxford University Press, 2011.

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Canada. Health and Welfare Canada. Environmental Health Directorate. Biological safety factors in toxicological risk assessment. Ottawa: Health and Welfare Canada, Environmental Health Directorate, 1990.

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Lisitsyn, Eugene M., Larissa I. Weisfeld y Anatoly I. Opalko. Biological Assessment of Natural and Anthropogenic Ecosystems. New York: Apple Academic Press, 2021. http://dx.doi.org/10.1201/9781003145424.

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Singh, Karan Deo. Forest biological diversity: Assessment and conservation planning. New Delhi: World Wide Fund for Nature, 2005.

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Wilton, Thomas F. Biological assessment of Iowa's wadeable streams: Project report. Des Moines, Iowa: Iowa Dept. of Natural Resources, 2004.

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Capítulos de libros sobre el tema "Biological assessment"

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Baker, Scott, Jeffrey Driver y David McCallum. "Biological Agents". En Residential Exposure Assessment, 245–61. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-1279-0_9.

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Mountford, Owen. "Wetland Assessment Methods: Biological Assessment". En The Wetland Book, 1–5. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-6172-8_287-1.

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Mountford, J. Owen. "Wetland Assessment Methods: Biological Assessment". En The Wetland Book, 1723–28. Dordrecht: Springer Netherlands, 2018. http://dx.doi.org/10.1007/978-90-481-9659-3_287.

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Sanford, Robert M. y Donald G. Holtgrieve. "Biological". En Environmental Impact Assessment in the United States, 103–14. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003030713-7.

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Fleming, Diane O. "Risk Assessment of Biological Hazards". En Biological Safety, 79–91. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815899.ch5.

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Wooley, Dawn P. y Diane O. Fleming. "Risk Assessment of Biological Hazards". En Biological Safety, 93–104. Washington, DC, USA: ASM Press, 2016. http://dx.doi.org/10.1128/9781555819637.ch5.

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Perera, Frederica P. "Biological Markers in Risk Assessment". En Carcinogen Risk Assessment, 123–38. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5484-0_10.

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Linden, Wolfgang y Paul L. Hewitt. "Behavioral and Biological Assessment". En Clinical Psychology, 179–94. 2nd edition. | New York, NY : Routledge, 2018. | Revised edition of: Clinical psychology. Boston : Prentice Hall, c2012.: Routledge, 2018. http://dx.doi.org/10.4324/9781351210409-9.

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Danso, S. K. A. "Assessment of biological nitrogen fixation". En Nitrogen Economy in Tropical Soils, 33–41. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-1706-4_4.

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Powell, M. R. "Risk Assessment for Biological Stressors". En Assessment and Management of Environmental Risks, 71–83. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0987-4_8.

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Actas de conferencias sobre el tema "Biological assessment"

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Kazachenko, A. V., A. E. Vasyuk y O. A. Esyakova. "ENVIRONMENTAL ASSESSMENT BY BIOLOGICAL TESTING". En ДАЛЬНЕВОСТОЧНАЯ ВЕСНА - 2021. Комсомольск-на-Амуре: Комсомольский-на-Амуре государственный университет, 2021. http://dx.doi.org/10.17084/978-5-7765-1472-2_2021_64.

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Yıldırım, Hüseyin, Azad Güler, Fusun Alatas, Sinan Erginel, Abdullah Kayıkcı y Tunahan Yüce. "Latent tuberculosis assessment before biological agent use". En ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2814.

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Campanella, Luigi. "Sensors for chemical risk assessment". En Optical Technologies for Industrial, Environmental, and Biological Sensing, editado por Tuan Vo-Dinh, Guenter Gauglitz, Robert A. Lieberman, Klaus P. Schaefer y Dennis K. Killinger. SPIE, 2004. http://dx.doi.org/10.1117/12.515596.

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"Assessment of Heavy Metal Pollution in Greenhouse Soils". En International Conference on Chemical, Environment & Biological Sciences. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c914133.

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Hu, Zhiyuan, Yushan Ding y Hao Song. "The life cycle assessment of automotive biological butanol". En 5th International Conference on Advanced Design and Manufacturing Engineering. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/icadme-15.2015.173.

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Delaney, L. "395. Biological Contaminants Assessment at a Former Tannery". En AIHce 2002. AIHA, 2002. http://dx.doi.org/10.3320/1.2766340.

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PRYAKHIN, E. A., G. A. TRYAPITSINA, L. I. URUTSKOYEV y A. V. AKLEYEV. "ASSESSMENT OF THE BIOLOGICAL EFFECTS OF “STRANGE” RADIATION". En Proceedings of the 11th International Conference on Cold Fusion. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812774354_0044.

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Campanella, L. y C. Costanza. "Sensoristic approach to biological damage and risk assessment". En RAVAGE OF THE PLANET 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/rav060271.

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"Integrating biological degradation potential into ecological risk assessment". En 22nd International Congress on Modelling and Simulation. Modelling and Simulation Society of Australia and New Zealand (MSSANZ), Inc., 2017. http://dx.doi.org/10.36334/modsim.2017.g6.tang.

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Makarova, Evgeniia y Galina Ignatova. "Assessment of biological therapy in asthma-obesity phenotype". En ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1408.

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Informes sobre el tema "Biological assessment"

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Brunner, Ken. Biological Assessment on Impacts to Peregrine Falcons. Fort Belvoir, VA: Defense Technical Information Center, marzo de 1994. http://dx.doi.org/10.21236/ada285130.

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Doyle, Robert D. y Bruce W. Byars. Lake Whitney Comprehensive Water Quality Assessment, Phase 1B- Physical and Biological Assessment (USDOE). Office of Scientific and Technical Information (OSTI), noviembre de 2009. http://dx.doi.org/10.2172/968980.

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Rogers, R. D., M. E. McIlwain, S. J. Losinski y D. D. Taylor. Research and engineering assessment of biological solubilization of phosphate. Office of Scientific and Technical Information (OSTI), marzo de 1993. http://dx.doi.org/10.2172/10141439.

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Rogers, R. D., M. E. McIlwain, S. J. Losinski y D. D. Taylor. Research and engineering assessment of biological solubilization of phosphate. Office of Scientific and Technical Information (OSTI), marzo de 1993. http://dx.doi.org/10.2172/6350337.

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May, Christopher W., Kathleen E. McGrath, David R. Geist, Timothy Abbe y Chase Barton. Grays River Watershed and Biological Assessment Final Report 2006. Office of Scientific and Technical Information (OSTI), febrero de 2008. http://dx.doi.org/10.2172/961997.

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May, Christopher y David Geist. Grays River Watershed and Biological Assessment, 2006 Final Report. Office of Scientific and Technical Information (OSTI), abril de 2007. http://dx.doi.org/10.2172/961998.

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McGrath, Kathleen E. Grays River Watershed and Biological Assessment, Annual Report 2005. Office of Scientific and Technical Information (OSTI), febrero de 2008. http://dx.doi.org/10.2172/962009.

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Fleishman, Erica. Sixth Oregon climate assessment. Oregon Climate Change Research Institute, Oregon State University, 2023. http://dx.doi.org/10.5399/osu/1161.

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Consistent with its charge under Oregon House Bill 3543, the Oregon Climate Change Research Institute (OCCRI) conducts a biennial assessment of the state of climate change science, including biological, physical, and social science, as it relates to Oregon and the likely effects of climate change on Oregon. This sixth Oregon Climate Assessment builds on the previous assessments by continuing to evaluate past and projected future changes in Oregon’s climate and water supply. Like the fifth assessment, it is structured with the goal of supporting the state’s mitigation planning for natural hazards and implementation of the 2021 Oregon Climate Change Adaptation Framework.
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Keller, D. C. Biological assessment for the transfer of the DP land tract. Office of Scientific and Technical Information (OSTI), octubre de 1996. http://dx.doi.org/10.2172/434451.

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Dalton, Meghan M. y Erica Fleishman. Fifth Oregon climate assessment. Oregon Climate Change Research Institute, Oregon State University, 2021. http://dx.doi.org/10.5399/osu/1160.

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Resumen
Consistent with its charge under Oregon House Bill 3543, the Oregon Climate Change Research Institute (OCCRI) conducts a biennial assessment of the state of climate change science, including biological, physical, and social science, as it relates to Oregon and the likely effects of climate change on Oregon. This fifth Oregon Climate Assessment builds on previous assessments (Dello and Mote 2010; Dalton et al. 2013, 2017; Mote et al. 2019) by continuing to evaluate past and projected future changes in Oregon’s climate and hydrology. This Assessment is structured with the goal of serving as a resource for the state’s mitigation planning for natural hazards and implementation of the 2021 Oregon Climate Change Adaptation Framework.
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