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Tesis sobre el tema "Biocompatibility"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 25 de julio de 2025

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1

Wang, Haibo. "Hydroxyapatite degradation and biocompatibility." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1087238429.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 190 p.; also includes graphics. Includes bibliographical references (p. 166-190).

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2

Roka, Eszter. "Biocompatibility evaluation and synthesis of macrocyclic compounds." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1027/document.

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La faible solubilité de certains médicaments cause des problèmes majeurs dans les formulations pharmaceutiques, puisque la solubilité dans l'eau est un critère indispensable pour la biodisponibilité. Les composés macrocycliques tels que les CDs et les calixarènes ont une cavité relativement hydrophobe, leur permettant ainsi d'encapsuler de nombreuses molécules. Les CDs ont déjà été utilisées comme excipients pharmaceutiques pour l'amélioration de la solubilité. La structure de ces macrocycles permet d'effectuer de nombreuses modifications, qui causent des changements tant au niveau de leurs ca

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3

Sun, Tao, and 孙韬. "Surface modification of titanium metal for medical applications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45457694.

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4

Reverte, Maëva. "Etude de la biocompatibilité d acides nucléiques modifiés par des acides boroniques : développement de nouveaux outils de diagnostic." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT236.

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La modification d’oligonucléotides est un domaine attrayant de la chimie organique. De nombreuses études se sont intéressées à la génération de liens internucléosidiques artificiels à visée thérapeutique, diagnostic ou encore pour des applications en chimie prébiotique. Ce manuscript de thèse rapporte la synthèse et l’étude de biocompatibilité d’acides nucléiques modifiés à leurs extrémités 5’ par un acide boronique. Les comportement des oligomères boroniques a été évalué en présence de différentes classes d’enzymes telles que les ligases, les polymérases ou encore les phosphodiestérases. Les

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5

Le, Coadou Cécile. "Caractérisation de films de zircone yttriée et développement d’un procédé de brasage avec du TA6V pour des applications biomédicales." Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAI041/document.

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Les maladies neurodégénératives sont en forte progression dans nos sociétés, mais elles sont également mieux connues et mieux soignées. Par exemple, la stimulation cérébrale profonde est de nos jours utilisée pour lutter contre des maladies comme la maladie de Parkinson. Pour cela, un boitier semblable à celui d'un pacemaker, placé sous la clavicule, est habituellement utilisé pour délivrer des impulsions électriques dans des zones spécifiques du cerveau grâce à des électrodes. Afin d'éviter certaines complications, un boitier ultrafin a été imaginé. Il peut être placé directement au niveau du

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6

Bentley, P. K. "Biocompatibility assessment of novel perfluorochemical emulsions." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293632.

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7

Campoccia, Davide. "Aspects of biocompatibility of hyaluronan derivatives." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295835.

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8

Blanquer, Jerez Andreu. "Biocompatibility of new biomaterials for orthopaedic applications." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/386500.

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L’ús de materials biocompatibles ha assolit una importància creixent en aplicacions ortopèdiques i quirúrgiques, degut a l’envelliment de la població. Els aliatges metàl·lics que s’empren actualment en medicina presenten propietats físiques i mecàniques diferents a les de l’os humà, incrementant la probabilitat de pèrdua de l’implant. Per aquesta raó, s’estan desenvolupant nous aliatges metàl·lics amb millors propietats. En aquest sentit, la present tesi té com objectiu l’anàlisi de la biocompatibilitat de nous aliatges pel seu ús en implants ortopèdics. En primer lloc, s’ha demostrat la bioco

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9

Zeng, Muling. "Bacterial cellulose: fabrication, characterization and biocompatibility studies." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/284146.

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En marzo de 2011, apliqué a una beca del CSC (Consejo de Becas de China), en cooperación con la Universitat Autònoma de Barcelona (UAB). Después de medio año, conseguí la beca y comencé mi tesis doctoral bajo la supervisión de la Dra. Anna Roig y la Dra. Anna Laromaine. Mi proyecto asignada era en celulosa bacteriana: su síntesis, caracterización y estudios de biocompatibilidad. La celulosa bacteriana es un polisacárido de fuentes renovables, y puede ser producida por algunos tipos de bacterias en la naturaleza. Presenta propiedades químicas y físicas notables, incluyendo una alta pureza quím

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10

Somayajula, Dilip Ayyala. "Biocompatibility of osteoblast cells on titanium implants." Cleveland, Ohio : Cleveland State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1207322725.

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Thesis (M.S.)--Cleveland State University, 2008.<br>Abstract. Title from PDF t.p. (viewed on May 8, 2008). Includes bibliographical references (p. 72-76). Available online via the OhioLINK ETD Center. Also available in print.

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11

Suwannasom, Nittiya [Verfasser]. "Biocompatibility of Biopolymer Submicron Particles / Nittiya Suwannasom." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1202044433/34.

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12

Fretwell, Grant Michael. "On the biocompatibility of nickel titanium alloys." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366485.

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13

Frykstrand, Ångström Sara. "Mesoporous magnesium carbonate : Synthesis, characterization and biocompatibility." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-281522.

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Mesoporous materials constitute a promising class of nanomaterials for a number of applications due to their tunable pore structure. The synthesis of most mesoporous materials involves a surfactant liquid crystal structure to form the pores. As well as the many advantages associated with this method of synthesis, there are disadvantages such as high production costs and a substantial environmental impact which limit the possibilities for large scale production. Therefore there is a need for other synthesis routes. The aim of the work described herein was to contribute to this field by developi

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14

Brendel, Christopher M. "Biocompatibility of Polymer Implants for Medical Applications." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1246892895.

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15

Christenson, Elizabeth. "Biostability and Biocompatibility of Modified Polyurethane Elastomers." Case Western Reserve University School of Graduate Studies / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=case1118268387.

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16

Ayyala, Somayajula Dilip. "Biocompatibility of osteoblast cells on titanium implants." Cleveland State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1207322725.

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17

Abraham, Nicole M. "Evaluation of Blood Vessel Mimic Scaffold Biocompatibility." DigitalCommons@CalPoly, 2021. https://digitalcommons.calpoly.edu/theses/2313.

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The Tissue Engineering Research Lab at California Polytechnic State University, San Luis Obispo focuses on creating tissue-engineered blood vessel mimics (BVMs) for use in preclinical testing of vascular devices. These BVMs are composed of electrospun scaffolds made of an assortment of polymers that are seeded with different cell types. This integration of polymers with cells leads to the need for biocompatibility testing of the polymer scaffolds. Many of the lab’s newest scaffolds have not been fully characterized for biologic interactions. Therefore, the first aim of this thesis developed me

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18

Félix, Pedro Tiago Albergaria. "Assessment of biocompatibility of selected ferroelectric ceramics." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/10711.

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Mestrado em Materiais e Dispositivos Biomédicos<br>Desde há muitas décadas que é sabido que os organismos vivos, em especial os tecidos, reagem fisicamente a estímulos eléctricos, podendo esses efeitos reproduzirem-se numa libertação de químicos endógenos, ou deformar a sua estrutura física. O tecido ósseo por si só é considerado um material/tecido piezoeléctrico, deformando-se mecanicamente quando lhe é induzido um estímulo eléctrico e vice-versa, ou seja, produz um potencial eléctrico quando sofre uma tracção ou compressão mecânica. A hipótese de que um material ferroeléctrico possa vir a p

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19

Yamamoto, Akiko. "Biocompatibility evaluation of metallic biomaterials in vitro." Kyoto University, 1998. http://hdl.handle.net/2433/182365.

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20

Yu, Young. "Enhancing the biocompatibility of coronary artery stents." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/16472.

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Cardiovascular disease, in particular coronary artery disease is a leading cause of morbidity and mortality worldwide. Coronary artery disease occurs as a consequence of atherosclerosis. Impediment to coronary blood flow causes myocardial ischemia, manifesting clinically as angina. Plaque rupture can lead to rapid vessel occlusion and myocardial necrosis. Revascularization (restoration of normal blood flow) can be achieved percutaneously with balloon angioplasty and coronary stent placement. Coronary stents are the most commonly implanted medical prostheses. To date the majority of commercial

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21

Barraud, Joanne Elizabeth. "The biocompatibility of novel phosphorylcholine based biomaterials." Thesis, University of Brighton, 2001. https://research.brighton.ac.uk/en/studentTheses/6dcb572f-e393-4a65-8c76-80c490a5d4f4.

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Many conventional biomaterials fail to meet the demands required of them with respect to their surface and bulk properties. This problem can be addressed by developing novel biomaterials that have the desired bulk properties and increased biocompatibility. Alternatively the surfaces of biomaterials which have the desired bulk properties can be modified to increase their biocompatibility without compromising these bulk properties. Phosphorylcholine (PC) based coatings mimic the surface of biological membranes and so offer a novel method for modifying bulk materials, or can be incorporated into

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22

Gladwin, Karen M. "Carbon nanotube biocompatibility with primary sensory neurons." Thesis, University of Brighton, 2010. https://research.brighton.ac.uk/en/studentTheses/7de21b7a-9c7c-4367-8e1c-ddbd347fd0c9.

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The repair of peripheral nerve lesions presents a common clinical challenge, with those injured suffering from an array of debilitating symptoms and sensory or motor handicaps. The current method of repairing peripheral nerve lesions involves the use of nerve autografts or artificial nerve repair conduits to bridge the gap between the two ends of the damaged nerve. However, results from the use of these techniques rarely produce full functional recovery. Several studies have shown that carbon nanotubes (CNTs) can be used as a successful substrate for the growth and guidance of neurons. These d

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23

Nouman, Micheal. "Effet de l'exsudation des additifs sur les propriétés d'usage d'un dispositif médical implantable (cathéter)." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS056/document.

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L'état de surface est l'un des paramètres les plus importants pour déterminer la biocompatibilité d'un dispositif médical implantable, tout changement à la surface une fois en contact avec les tissus corporels peut avoir un impact sur la réponse biologique (cytotoxicité, inflammation, irritation, thrombose ... etc.). Pendant le stockage, l’exsudation des additifs peut se produire à la surface des polymères et modifier leurs propriétés. Dans cette étude, nous utilisons du polyuréthane à base de cathéter (Pellethane®), en raison de ses nombreuses applications dans le domaine des dispositifs médi

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24

González, Paz Rodolfo Jesús. "Polyurethanes based on fatty acids with improved biocompatibility." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/96663.

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El objetivo principal de esta tesis ha sido el desarrollo de nuevos poliuretanos a partir de ácidos grasos como fuentes renovables, utilizando química “click” en la síntesis de los dioles y polioles correspondientes. La primera parte del trabajo describe la preparación de los monómeros “vía” acoplamiento tiol-eno ó tiol-ino, su caracterización y las propiedades de los poliuretanos sintetizados. Como los polímeros a partir de ácidos grasos provienen de macromoléculas biológicas y pueden ser potencialmente biocompatibles, la segunda parte del trabajo está dirigida a incrementar la biocompatibili

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25

Kapanen, A. (Anita). "Biocompatibility of orthopaedic implants on bone forming cells." Doctoral thesis, University of Oulu, 2002. http://urn.fi/urn:isbn:9514266064.

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Abstract Reindeer antler was studied for its possible use as a bone implant material. A molecular biological study showed that antler contains a growth factor promoting bone formation. Ectopic bone formation assay showed that antler is not an equally effective inducer as allogenic material. Ectopic bone formation assay was optimised for biocompatibility studies of orthopaedic NiTi implants. Ti-6Al-4V and stainless steel were used as reference materials. The assay showed differences in bone mineral densities, with superior qualities in NiTi. The rate of endochondral ossification varie

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26

Pulletikurthi, Chandan. "Biocompatibility Assessment of Biosorbable Polymer Coated Nitinol Alloys." FIU Digital Commons, 2014. http://digitalcommons.fiu.edu/etd/1552.

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Owing to an increased risk of aging population and a higher incidence of coronary artery disease (CAD), there is a need for more reliable and safer treatments. Numerous varieties of durable polymer-coated drug eluting stents (DES) are available in the market in order to mitigate in-stent restenosis. However, there are certain issues regarding their usage such as delayed arterial healing, thrombosis, inflammation, toxic corrosion by-products, mechanical stability and degradation. As a result, significant amount of research has to be devoted to the improvement of biodegradable polymer-coated imp

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27

McDougall, Kathleen Emma. "Evaluation of biocompatibility using human craniofacial bone cells." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368260.

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28

Cohen, Sarah J. (Sarah Jennifer). "Biocompatibility of an implantable ophthalmic drug delivery device." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39871.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.<br>Includes bibliographical references (p. 90-94).<br>Diseases of the posterior eye present clinicians with a treatment challenge mainly due to the region's inaccessible location. Several drugs, including those available for the treatment of exudative age-related macular degeneration, are currently delivered by periodic injection into the eyeball. To avoid the risks and complications associated with this method, several implantable, timed release devices have been investigated to deliver these drugs di

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29

William, V. G., Володимир Миколайович Дейнека, Владимир Николаевич Дейнека, et al. "In-vivo testing of spongy titanium implant biocompatibility." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/31970.

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The conducted experiment shows porous titanium implant biocompatibility and existence of conductive features. This results leads to further research concerning this materials possible usage in osteoplasty. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/31970

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30

Bernard, Mélisande. "Etude de biocompatibilité des films à base de COC en tant que matériaux implantables." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS378.

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L’objet de ce travail est l’étude de la biocompatibilité in vitro des matériaux à base de COC, afin d’évaluer leur potentiel de biomatériaux implantables.Cette évaluation est réalisée par le suivi de plusieurs paramètres : viabilité cellulaire/cytotoxicité, évaluation des phénomènes de stress oxydant, inflammatoires et hémocompatibilité. Une relation entre ces réponses biologiques et les propriétés physico chimiques des matériaux étudiés a été appréhendée.Les résultats montrent une bonne biocompatibilité des films testés avec un impact significatif de la présence des additifs (anti-oxydant et

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31

Beaufils, Sylvie. "Synthèse électrochimique et caractérisation de nanoparticules d'hydroxypatite, mise en charge de matrices extracellulaires d'hydrogel et leurs caractérisations mécaniques et biologiques." Thesis, Reims, 2018. http://www.theses.fr/2018REIMS031/document.

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Dans le but de réduire la morbidité et la durée d’hospitalisation, la médecine régénérative progresse de nos jours vers le développement de techniques chirurgicales moins invasives. Cette recherche en chirurgie mini-invasive a motivé le développement de matrices injectables pour l’ingénierie tissulaire osseuse. Ces matrices doivent aussi être capables de durcir une fois injectées in situ, acquérir la forme souhaitée ainsi que des propriétés mécaniques compatibles avec le tissu hôte qu’elles doivent réparer. De nombreux hydrogels sont déjà employés pour cette application mais aucun ne remplit c

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32

Ryhänen, J. (Jorma). "Biocompatibility evaluation of nickel-titanium shape memory metal alloy." Doctoral thesis, Oulun yliopisto, 1999. http://urn.fi/urn:isbn:9514252217.

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Abstract The shape memory effect, superelasticity, and good damping properties, uncommon in other implant alloys, make the nickel-titanium shape memory metal alloy (Nitinol or NiTi) a fascinating material for surgical applications. It provides a possibility to make self-locking, self-expanding and self-compressing implants. The purpose of this work was to determine if NiTi is a safe material for surgical implant applications. The primary cytotoxicity and the corrosion rate of NiTi were assessed in human osteoblast and fibroblast cell cultures. Comparisons were made with 316 LVM stainless stee

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33

Long, Susanna. "Factors affecting the biocompatibility of novel phosphorylcholine based biomaterials." Thesis, University of Brighton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405288.

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Phosphorylcholine (PC) based polymers have been used in medical devices to improve biocompatibility. In this study, PC based polymers were modified with either a cationic charge or combined with poly(butylmethacrylate) (PBMA) and their biocompatibility assessed through a series of biological assays. Protein adsorption assays revealed that the presence of a cationic charge significantly increased the number of proteins adsorbed. The total amount of protein adsorbed to PC with 30% cationic charge was considerably more then that adsorbed to the other samples. Fibronectin, albumin, complement fact

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34

Martines, Elena. "Surfaces with periodic nano-features : physical properties and biocompatibility." Thesis, University of Glasgow, 2006. http://theses.gla.ac.uk/3900/.

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The behaviour of animal cells in vitro is affected by both the chemistry and the shape of the surface (“topography”) to which they adhere. Culturing animal cells on nanopatterns of different shape, dimensions and chemistry considerably modifies cell attachment, spreading, proliferation, migration and gene expression. This work was primarily aimed at elucidating the influence of nanopatterning on some physical properties of the substrate. The contact angle of water on nanopatterned silicon was measured, and the predicted DLVO (Derjaguin-Landau-Verweey-Overbeek) interaction between a nanopattern

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35

Notara, Maria D. "Characterisation and biocompatibility of novel chitosan-alginata blend membranes." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423279.

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36

Seamen, P. J. "Investigation into the biocompatibility of modified synthetic polymer surfaces." Thesis, University of Salford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381699.

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37

Watkins, Lucy. "Radio frequency plasma treatment of polymers for improved biocompatibility." Thesis, University of York, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441055.

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38

Hua, Kai. "Nanocellulose for Biomedical Applications : Modification, Characterisation and Biocompatibility Studies." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-267301.

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In the past decade there has been increasing interest in exploring the use of nanocellulose in medicine. However, the influence of the physicochemical properties of nanocellulose on the material´s biocompatibility has not been fully investigated. In this thesis, thin films of nanocellulose from wood (NFC) and from Cladophora algae (CC) were modified by the addition of charged groups on their surfaces and the influence of these modifications on the material´s physicochemical properties and on cell responses in vitro was studied. The results indicate that the introduction of charged groups on t

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39

Zhu, Lin. "Biocompatibility of Carbon Nanomaterials: Materials Characterization and Cytotoxicity Evaluation." University of Dayton / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1343744183.

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40

Huber, Daniel Edward. "Structure and Properties of Titanium Tantalum Alloys for Biocompatibility." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1480589088123473.

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41

Jeewandara, Thamarasee M. "Bioengineering Stents for Proactive Biocompatibility: From Biomaterials to Stents." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14974.

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The thesis describes methods to characterize modified biomaterial surfaces in vitro, and investigate its short term implications at the artery interface in vivo. Plasma activated coating (PAC) technology has been previously deposited on a stainless steel biomaterial (316LSS), investigated in the stent form in vivo. Initial histopathology characterizations conducted with resin-artery-stents evaluate artery-stent interface interactions in vivo. The 7 day pilot study was followed by detailed material characterization and biofunctionalization on a modified cobalt chromium metal alloy L605, for the

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42

Källrot, Martina. "Covalent Surface Modification of Degradable Polymers for Increased Biocompatibility." Licentiate thesis, KTH, Fiber- och polymerteknik, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-579.

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Degradable polymers have gained an increased attention in the field of biomedical applications over the past decades, for example in tissue engineering. One way of improving the biocompatibility of these polymers is by chemical surface modification, however the risk of degradation during the modification procedure is a limiting factor. In some biomedical applications, for example in nerve guides, a patterned surface is desired to improve the cell attachment and proliferation. In this thesis a new non-destructive, single-step, and solvent free method for surface modification of degradable polym

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43

Chan, Yee-loi, and 陳以來. "Surface modification of NiTi for long term orthopedic applications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557406.

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44

Lakbakbi, Souad. "Adhésion et activation des cellules sanguines par une membrane d'hémodialyse (AN-69ST) : conséquence sur l'expression de facteur tissulaire et la thrombogénecité de la membrane." Thesis, Reims, 2014. http://www.theses.fr/2014REIMS012/document.

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L'objectif de ce travail est d'évaluer le rôle du facteur tissulaire (FT) dans l'initiation de la coagulation d'un circuit d'hémodialyse. A partir de l'analyse des membranes d'hémodialyse, nous avons observé que les leucocytes et, majoritairement les polynucléaires neutrophiles (PNN) adhéraient aux membranes hémocompatibles (de type AN69ST). Ces cellules expriment un FT fonctionnel. Nous avons développé différents modèles d'étude de l'expression du FT par les PNN. A partir de PNN humains obtenus chez des sujets sains, nous montrons que les PNN expriment le FT après stimulation par le TNF. L'IL

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45

Cottance, Myline. "Contribution au développement d'interfaces neuro-électroniques." Thesis, Paris Est, 2014. http://www.theses.fr/2014PEST1105/document.

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Les travaux menés au cours de cette thèse portent sur la microfabrication d'interfaces neuro-électroniques pour des applications en neurosciences. Nous avons choisi de nos focaliser sur la réhabilitation fonctionnelle motrice et sensorielle en développant différentes matrices de micro-électrodes (MEA) respectivement, des sondes neuronales rigides et des implants rétiniens souples. Selon les applications visées, deux types de substrats ont été utilisés pour concevoir ces MEA. Pour des analyses ou expériences in-vitro, les MEA (sondes neuronales) ont plutôt été réalisées sur des substrats rigide

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46

Ljunggren, Lennart. "Biothermodynamic studies of blood components with special reference to biocompatibility." Lund : Dept. of Clinical Chemistry, University Hospital, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39117042.html.

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47

Kujala, S. (Sauli). "Biocompatibility and biomechanical aspects of Nitinol shape memory metal implants." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514271246.

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Abstract Nickel-titanium shape memory metal Nitinol (NiTi) is a new kind of implant material, which provides a possibility to prepare functional implants activated at body temperature and withstands kinking better than conventional metals. Applications utilizing these unique properties are a target of active research interest. Host reactions to NiTi and to the forces created by functional implants should also be studied. A functional NiTi intramedullary nail, which causes a bending force on the bone, was developed for correcting bone deformities. In the present studies, the action of the devi

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48

Haider, Waseem. "Enhanced Biocompatibility of NiTi (Nitinol) Via Surface Treatment and Alloying." FIU Digital Commons, 2010. http://digitalcommons.fiu.edu/etd/177.

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It is projected that by 2020, there will be 138 million Americans over 45, the age at which the increased incidence of heart diseases is documented. Many will require stents. This multi-billion dollar industry, with over 2 million patients worldwide, 15% of whom use Nitinol stents have experienced a decline in sales recently, due in part to thrombosis. It is a sudden blood clot that forms inside stents. As a result, the Food and Drug Administration and American Heart Association are calling for a new generation of stents, new designs and different alloys that are more adaptable to the arteries

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49

Kidani, Derrick D. A. "Surface modifications to improve the biocompatibility of polymeric vascular prostheses." Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/11263.

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Ruan, Jianming. "Characterisation and biocompatibility evaluation of calcium phosphate biomaterials in vitro." Thesis, University of Strathclyde, 2000. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21172.

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Medical applications of calcium phosphate biomaterials are limited because of poor mechanical properties and acute inflammation reactions which take place occasionally in the clinic. To increase the usefulness of calcium phosphate biomaterials it is necessary to improve the mechanical properties and biological character. Processing and characterization of porous hydroxyapatite (HA) and dense composite (HA-Spinel) biomaterials have been performed in the present research. Biocompatibility of these biomaterials has been examined in vitro using human and rat immortalized osteoblast cells, and the

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