Literatura académica sobre el tema "Biliary secretion"
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Artículos de revistas sobre el tema "Biliary secretion"
Blot-Chabaud, M., M. Dumont, M. Corbic y S. Erlinger. "Effect of acid-base balance on biliary bicarbonate secretion in the isolated perfused guinea pig liver". American Journal of Physiology-Gastrointestinal and Liver Physiology 258, n.º 6 (1 de junio de 1990): G863—G872. http://dx.doi.org/10.1152/ajpgi.1990.258.6.g863.
Texto completoUc, Aliye, Radhamma Giriyappa, David K. Meyerholz, Michelle Griffin, Lynda S. Ostedgaard, Xiao Xiao Tang, Marwa Abu-El-Haija et al. "Pancreatic and biliary secretion are both altered in cystic fibrosis pigs". American Journal of Physiology-Gastrointestinal and Liver Physiology 303, n.º 8 (15 de octubre de 2012): G961—G968. http://dx.doi.org/10.1152/ajpgi.00030.2012.
Texto completoSætre, S. S., N. J. Andersen, T. Houe, P. Svendsen, J. F. Rehfeld, O. Olsen y O. B. Schaffalitzky de Muckadell. "Regulation of porcine biliary secretion by secretin". Acta Physiologica Scandinavica 163, n.º 1 (mayo de 1998): 113–19. http://dx.doi.org/10.1046/j.1365-201x.1998.00349.x.
Texto completoAlpini, G., R. Lenzi, W. R. Zhai, P. A. Slott, M. H. Liu, L. Sarkozi y N. Tavoloni. "Bile secretory function of intrahepatic biliary epithelium in the rat". American Journal of Physiology-Gastrointestinal and Liver Physiology 257, n.º 1 (1 de julio de 1989): G124—G133. http://dx.doi.org/10.1152/ajpgi.1989.257.1.g124.
Texto completoZeniya, M. y A. Reuben. "Triton WR-1339-induced changes in serum lipids and biliary lipid secretion". American Journal of Physiology-Gastrointestinal and Liver Physiology 254, n.º 3 (1 de marzo de 1988): G346—G354. http://dx.doi.org/10.1152/ajpgi.1988.254.3.g346.
Texto completoHofmann, Alan F. "Biliary Secretion: Future Perspectives". Digestion 58, n.º 1 (1997): 24–28. http://dx.doi.org/10.1159/000201519.
Texto completoReuben, A., P. N. Maton, G. M. Murphy y R. H. Dowling. "Bile Lipid Secretion in Obese and Non-Obese Individuals with and without Gallstones". Clinical Science 69, n.º 1 (1 de julio de 1985): 71–79. http://dx.doi.org/10.1042/cs0690071.
Texto completoChanussot, F., H. Lafont, J. Hauton, B. Tuchweber y I. Yousef. "Studies on the origin of biliary phospholipid. Effect of dehydrocholic acid and cholic acid infusions on hepatic and biliary phospholipids". Biochemical Journal 270, n.º 3 (15 de septiembre de 1990): 691–95. http://dx.doi.org/10.1042/bj2700691.
Texto completoHan, Yuyan, Paolo Onori, Fanyin Meng, Sharon DeMorrow, Julie Venter, Heather Francis, Antonio Franchitto et al. "Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis". American Journal of Physiology-Gastrointestinal and Liver Physiology 307, n.º 9 (1 de noviembre de 2014): G894—G904. http://dx.doi.org/10.1152/ajpgi.00288.2014.
Texto completoVerkade, H. J., R. Havinga, A. Gerding, R. J. Vonk y F. Kuipers. "Mechanism of bile acid-induced biliary lipid secretion in the rat: effect of conjugated bilirubin". American Journal of Physiology-Gastrointestinal and Liver Physiology 264, n.º 3 (1 de marzo de 1993): G462—G469. http://dx.doi.org/10.1152/ajpgi.1993.264.3.g462.
Texto completoTesis sobre el tema "Biliary secretion"
Baxter, Debbie Jane. "Molecular mechanisms of biliary lipid secretion". Thesis, Liverpool John Moores University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298908.
Texto completoMareux, Elodie. "Pharmacothérapie ciblée des déficits en ABCB11". Electronic Thesis or Diss., université Paris-Saclay, 2021. http://www.theses.fr/2021UPASL083.
Texto completoABCB11/BSEP (Bile Salt Export Pump) is expressed at the canalicular membrane of hepatocytes. It ensures bile acids secretion into bile which is essential for biliary secretion. Nearly 400 variations of the ABCB11 gene have been identified and are associated with rare hepatobiliary diseases, the most severe being progressive familial intrahepatic cholestasis type 2 (PFIC2). The effectiveness of medical treatments is limited. Consequently, liver transplantation is required before adulthood for almost 2/3 of PFIC2 patients. In this context, the identification of alternative therapies is a major challenge.This thesis focuses on personalized therapeutic strategies to correct the pathological consequences of some ABCB11 variations identified in patients. The A257V, G562D and T463I variations of ABCB11 were studied by 3D molecular modelling. These variations were responsible for a defect in Abcb11 transport function. Ivacaftor (VX-770, Kalydeco®), a clinically approved cystic fibrosis treatment, corrects the activity defect of the three variants.Similar effects were observed with GLPG1837, SBC040 and SBC219, known as potentiators of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator).From a combinatory therapy perspective, we also demonstrated the ability of these potentiators to correct the transport defect of the R1090C and R1090W variants, potential readthrough products of the R1090X nonsense variant. We also evaluated the ability of Elexacaftor (VX-445) and Tezacaftor (VX 661) correctors of CFTR. These correctors, alone or in combination, restored trafficking of the R1128C missense variant, leading to a significant increase in the transport function. Interestingly, the addition of potentiators abolishes this effect.Altogether, this thesis constitutes a proof of concept that molecules with high therapeutic potential can correct the molecular defects of ABCB11 variants. These treatments could increase the pharmacopoeia available for patients with ABCB11 deficiency and thus delay or even suppress the need for liver transplantation
LANGLOIS, ANNIK. "Contribution a l'etude de la regulation hormonale des secretions digestives chez le porc : effets du polypeptide pancreatique sur la secretion pancreatique exocrine et la secretion biliaire chez l'animal conscient". Paris 7, 1989. http://www.theses.fr/1989PA077080.
Texto completoLam, Pak-yan Ian y 林柏炘. "Secretin in biliary physiology: autocrine regulation on cholangiocyte proliferation and negative feedbackregulation on duodenal secretin expression via bile acids". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43572327.
Texto completoLam, Pak-yan Ian. "Secretin in biliary physiology autocrine regulation on cholangiocyte proliferation and negative feedback regulation on duodenal secretin expression via bile acids /". Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43572327.
Texto completoZanninelli, Giuliana. "Effets de chelateurs sur le routage cellulaire du fer non lie a la transferrine (doctorat : biologie et sciences de la sante)". Rennes 1, 2000. http://www.theses.fr/2000REN1B044.
Texto completoDupuy-Esnault, Christine. "Relation entre le cholestérol libre des HDL et des LDL et la secretion biliaire du cholestérol et des sels biliaires : influence de divers régimes hyperlipidiques". Aix-Marseille 2, 1986. http://www.theses.fr/1986AIX22066.
Texto completoBruneau, Alix. "Régulation de l'expression membranaire du transporteur de phospholipides biliaires ABCB4 : effet de mutations Functional Defect of Variants in the Adenosine Triphosphate–Binding Sites of ABCB4 and Their Rescue by the Cystic Fibrosis Transmembrane Conductance Regulator Potentiator, Ivacaftor (VX-770) Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS048.
Texto completoABCB4 is exclusively expressed at the canalicular membrane of hepatocytes where its function is to translocate phosphatidylcholine (PC) into bile. Variations in ABCB4 gene sequence are associated with several chronic and progressive liver diseases. The most severe is PFIC3 which develops early in childhood and most often requires liver transplantation. Less severe diseases are the intrahepatic cholestasis of pregnancy and the low phospholipid- associated cholelithiasis syndrome which occur in young adults. Up to now, about 500 disease-causing ABCB4 variants have been reported. A challenge is to find pharmacological treatments for the severe forms of the diseases. We have studied the effect of five disease-causing variations that reside in the highly conserved motifs of ABC transporters, involved in ATP binding. Using three-dimension structural modeling and in vitro studies, we showed that the five mutants were normally processed and targeted to the plasma membrane, whereas their PC secretion activity was dramatically decreased. PC secretion activity of the mutants was rescued by the clinically approved CFTR potentiator ivacaftor (VX-770). These results pave the way for personalized therapy in ABCB4-related diseases.The second part of my project was aimed at investigating the potential role of two ABCB4 partners, the kinase MRCKalpha and its effector the myosin light chain II (MLCII) in the expression and function of ABCB4. We found that downregulation of both partners didn’t affect the canalicular localization of ABCB4 but led to a reduction of its endocytosis. Our results open new insights into the mechanisms underlying the regulation of ABCB4 expression and function
Sutherland, Jessica Elin. "The kinetics of absorption, tissue distribution, biliary secretion, and urinary excretion of ingested aluminum". 1997. http://catalog.hathitrust.org/api/volumes/oclc/40160453.html.
Texto completoMustacich, Debbie J. "The microtubule system and the canalicular mdr2 P-glycoprotein play a role in the intracellular transport and biliary secretion of ��-Tocopherol and phosphatidylcholine in rats and mice". Thesis, 1998. http://hdl.handle.net/1957/34062.
Texto completoLibros sobre el tema "Biliary secretion"
Hamlin, Sandra Mary. Modulation of biliary lipid secretion. Birmingham: University of Birmingham, 1990.
Buscar texto completoMustacich, Debbie J. The microtubule system and the canalicular mdr2 P-glycoprotein play a role in the intracellular transport and biliary secretion of Ü-Tocopherol and phosphatidylcholine in rats and mice. 1998.
Buscar texto completoCapítulos de libros sobre el tema "Biliary secretion"
Zimniak, Piotr y Roger Lester. "Disorders of Biliary Secretion". En Molecular Biology of Membrane Transport Disorders, 519–39. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1143-0_26.
Texto completoCarulli, Nicola, Paola Loria, Marco Bertolotti y Alberto Tripodi. "Determinants of Biliary Cholesterol Secretion". En Assessment and Management of Hepatobiliary Disease, 49–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-72631-6_7.
Texto completoColeman, R., K. L. Rahman, M. E. Bellringer y M. Carrella. "Biliary Lipid Secretion and its Control". En Bile Acids in Health and Disease, 43–60. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1249-6_4.
Texto completoKuipers, Folkert, Ronald P. J. Oude Elferink, Henkjan J. Verkade y Albert K. Groen. "Mechanisms and (Patho)Physiological Significance of Biliary Cholesterol Secretion". En Subcellular Biochemistry, 295–318. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5901-6_11.
Texto completoLirussi, F. y L. Okolicsanyi. "The Effect of Drugs on Liver Function and Biliary Secretion". En Biochemical Pharmacology as an Approach to Gastrointestinal Disorders, 239–47. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5390-4_19.
Texto completoBarbara, L., G. Mazzella, N. Villanova, P. Simoni, M. Ronchi, A. Roda, E. Roda y F. Bazzoli. "Effect of Gemfibrozil Administration on Biliary Lipid Secretion: A Crossover Study with Clofibrate". En Drugs Affecting Lipid Metabolism, 350–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71702-4_65.
Texto completoBentham Science Publisher, Bentham Science Publisher. "Biliary Secretion". En FFunctional Molecular Imaging In Hepatology (Open Access), 49–75. BENTHAM SCIENCE PUBLISHERS, 2012. http://dx.doi.org/10.2174/978160805290511201010049.
Texto completoPal, Gopal, Pravati Pal y Nivedita Nanda. "Biliary Secretion". En Comprehensive Textbook of Medical Physiology (Volume 1), 378. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/12960_43.
Texto completoFeher, Joseph. "Pancreatic and Biliary Secretion". En Quantitative Human Physiology, 810–20. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800883-6.00080-x.
Texto completoMiller, Laurence J. "Gallbladder and Biliary Secretion". En Encyclopedia of Endocrine Diseases, 94–96. Elsevier, 2004. http://dx.doi.org/10.1016/b0-12-475570-4/00497-2.
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