Bibliografías temáticas / Azaspiracidi

Literatura académica sobre el tema "Azaspiracidi"

Autor: Grafiati
Publicado: 1 de abril de 2023

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Índice

Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "Azaspiracidi".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Artículos de revistas sobre el tema "Azaspiracidi"

1

Hamilton, Brett, Mónica Díaz Sierra, Mary Lehane, Ambrose Furey y Kevin J. James. "The fragmentation pathways of azaspiracids elucidated using positive nanospray hybrid quadrupole time-of-flight (QqTOF) mass spectrometry". Spectroscopy 18, n.º 2 (2004): 355–62. http://dx.doi.org/10.1155/2004/949018.

Texto completo
Resumen
The azaspiracids, AZA1, AZA2 and AZA3, are the predominant shellfish toxins responsible for the human toxic syndrome, azaspiracid poisoning. Collision induced dissociation (CID) mass spectra were generated for azaspiracids using nano-electrospray ionisation (ESI) with a hybrid quadrupole time-of-flight (QqTOF) mass spectrometer in positive mode. Six main backbone fragmentations of the polyether skeleton of azaspiracids were observed as well as multiple neutral losses of water molecules from the parent and product ions. The characteristic charge-remote fragmentation of the carbon skeleton of azaspiracids produced nitrogenous ions. The three azaspiracids differ from one another by 14 Da due to methylation in the A- and E-rings. Three fragmentation pathways, involving cleavage of the E-ring, C27–C28 and G-ring, gave ions that were common to all azaspiracids. Another three fragmentations involving the A-ring, C-ring and C19–C20, were useful for distinguishing between azaspiracid analogues. Multiple tandem ion‒trap mass spectrometry (MSn) was used to confirm the fragmentation pathways.
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Kilcoyne, Jane, Adela Keogh, Ger Clancy, Patricia LeBlanc, Ian Burton, Michael A. Quilliam, Philipp Hess y Christopher O. Miles. "Improved Isolation Procedure for Azaspiracids from Shellfish, Structural Elucidation of Azaspiracid-6, and Stability Studies". Journal of Agricultural and Food Chemistry 60, n.º 10 (2 de marzo de 2012): 2447–55. http://dx.doi.org/10.1021/jf2048788.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Abal, Paula, M. Carmen Louzao, María Fraga, Natalia Vilariño, Sara Ferreiro, Mercedes R. Vieytes y Luis M. Botana. "Absorption and Effect of Azaspiracid-1 Over the Human Intestinal Barrier". Cellular Physiology and Biochemistry 43, n.º 1 (2017): 136–46. http://dx.doi.org/10.1159/000480331.

Texto completo
Resumen
Background: Azaspiracids (AZAs) are marine biotoxins produced by the dinoflagellates genera Azadinium and Amphidoma. These toxins cause azaspiracid poisoning (AZP), characterized by severe gastrointestinal illness in humans after the consumption of bivalve molluscs contaminated with AZAs. The main aim of the present study was to examine the consequences of human exposure to AZA1 by the study of absorption and effects of the toxin on Caco-2 cells, a reliable model of the human intestine. Methods: The ability of AZA1 to cross the human intestinal epithelium has been evaluated by the Caco-2 transepithelial permeability assay. The toxin has been detected and quantified using a microsphere-based immunoassay. Cell alterations and ultrastructural effects has been observed with confocal and transmission electron microscopy Results: AZA1 was absorbed by Caco-2 cells in a dose-dependent way without affecting cell viability. However, modifications on occludin distribution detected by confocal microscopy imaging indicated a possible monolayer integrity disruption. Nevertheless, transmission electron microscopy imaging revealed ultrastructural damages at the nucleus and mitochondria with autophagosomes in the cytoplasm, however, tight junctions and microvilli remained unaffected. Conclusion: After the ingestion of molluscs with the AZA1, the toxin will be transported through the human intestinal barrier to blood causing damage on epithelial cells.
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Trainer, Vera L. y Teri L. King. "SoundToxins: A Research and Monitoring Partnership for Harmful Phytoplankton in Washington State". Toxins 15, n.º 3 (2 de marzo de 2023): 189. http://dx.doi.org/10.3390/toxins15030189.

Texto completo
Resumen
The more frequent occurrence of marine harmful algal blooms (HABs) and recent problems with newly-described toxins in Puget Sound have increased the risk for illness and have negatively impacted sustainable access to shellfish in Washington State. Marine toxins that affect safe shellfish harvest because of their impact on human health are the saxitoxins that cause paralytic shellfish poisoning (PSP), domoic acid that causes amnesic shellfish poisoning (ASP), diarrhetic shellfish toxins that cause diarrhetic shellfish poisoning (DSP) and the recent measurement of azaspiracids, known to cause azaspiracid poisoning (AZP), at low concentrations in Puget Sound shellfish. The flagellate, Heterosigma akashiwo, impacts the health and harvestability of aquacultured and wild salmon in Puget Sound. The more recently described flagellates that cause the illness or death of cultivated and wild shellfish, include Protoceratium reticulatum, known to produce yessotoxins, Akashiwo sanguinea and Phaeocystis globosa. This increased incidence of HABs, especially dinoflagellate HABs that are expected in increase with enhanced stratification linked to climate change, has necessitated the partnership of state regulatory programs with SoundToxins, the research, monitoring and early warning program for HABs in Puget Sound, that allows shellfish growers, Native tribes, environmental learning centers and citizens, to be the “eyes on the coast”. This partnership enables safe harvest of wholesome seafood for consumption in the region and helps to describe unusual events that impact the health of oceans, wildlife and humans.
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Kilcoyne, Jane, Pearse McCarron, Michael J. Twiner, Ciara Nulty, Sheila Crain, Michael A. Quilliam, Frode Rise, Alistair L. Wilkins y Christopher O. Miles. "Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, andin VitroToxicity of 37-epi-Azaspiracid-1". Chemical Research in Toxicology 27, n.º 4 (7 de febrero de 2014): 587–600. http://dx.doi.org/10.1021/tx400434b.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Krock, Bernd, Urban Tillmann, Uwe John y Allan D. Cembella. "Characterization of azaspiracids in plankton size-fractions and isolation of an azaspiracid-producing dinoflagellate from the North Sea". Harmful Algae 8, n.º 2 (enero de 2009): 254–63. http://dx.doi.org/10.1016/j.hal.2008.06.003.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

OFUJI, Katsuya, Masayuki SATAKE, Terry MCMAHON, Kevin J. JAMES, Hideo NAOKI, Yasukatsu OSHIMA y Takeshi YASUMOTO. "Structures of Azaspiracid Analogs, Azaspiracid-4 and Azaspiracid-5, Causative Toxins of Azaspiracid Poisoning in Europe". Bioscience, Biotechnology, and Biochemistry 65, n.º 3 (enero de 2001): 740–42. http://dx.doi.org/10.1271/bbb.65.740.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Rossi, Rachele, Carmela Dell’Aversano, Bernd Krock, Patrizia Ciminiello, Isabella Percopo, Urban Tillmann, Vittorio Soprano y Adriana Zingone. "Mediterranean Azadinium dexteroporum (Dinophyceae) produces six novel azaspiracids and azaspiracid-35: a structural study by a multi-platform mass spectrometry approach". Analytical and Bioanalytical Chemistry 409, n.º 4 (7 de noviembre de 2016): 1121–34. http://dx.doi.org/10.1007/s00216-016-0037-4.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Li, Jialiang, Xiaohua Li y David R. Mootoo. "Synthetic and Computational Studies on the ABC Trioxadispiroketal Subunit of the Marine Biotoxin Azaspiracid-1". Natural Product Communications 3, n.º 11 (noviembre de 2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301106.

Texto completo
Resumen
The trioxadispiroketal residue in the marine biotoxin azaspiracid-1, which exists in a configuration capable of exhibiting a double anomeric effect, is believed to be the thermodynamically most stable bis-spiroketal diastereomer. In order to get insight into how structural factors affect this equilibrium, a simplified ABC trioxadispiroketal analog of azaspiracid-1 was synthesized and subjected to equilbration and computational studies. Compound 7, which represents a double anomeric effect was obtained as the major isomer, together with diastereomers 14 and 15, in a respective ratio of 62:22:16. DFT calculations for 7, 14 and 15 qualitatively matched this observation. These results suggest that while a double anomeric effect may play a major role in the stability of the trioxadispiroketal configuration in the more complex natural product, the substitution pattern of the C ring is also a contributing factor.
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Alfonso, Carmen, Amparo Alfonso, Paz Otero, Paula Rodríguez, Mercedes R. Vieytes, Chris Elliot, Cowan Higgins y Luis M. Botana. "Purification of five azaspiracids from mussel samples contaminated with DSP toxins and azaspiracids". Journal of Chromatography B 865, n.º 1-2 (abril de 2008): 133–40. http://dx.doi.org/10.1016/j.jchromb.2008.02.020.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
Más fuentes

Tesis sobre el tema "Azaspiracidi"

1

Kenton, Nathaniel T. "Total Synthesis of Azaspiracid-3, C20-epi-Azaspiracid-3, and Structural Definition of the Azaspiracids". The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523545452232749.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Okumu, Antony A. "Toward Total Synthesis of Azaspiracid-3 and Azaspiracid-34". The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461282755.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Yue, Ding. "Towards the total synthesis of Azaspiracid-3". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1284488476.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Zhou, Feng. "Synthesis of The ABCD Domain of The Azaspiracids". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1267992158.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Mzoughet, Kouassi ahou Judith Elisabeth Patricia. "Physiochemical and proteomic studies on azaspiracid contaminated mussels". Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517086.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Zhang, Zhigao. "Efforts towards the Total Synthesis of Azaspiracid-3". The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366108671.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Chen, Yong. "Synthetic Studies on Total Synthesis of Azaspiracid-3". The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1385895424.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Adu-Ampratwum, Daniel Dr. "Synthesis of the ABCD- and EFGHI-Domains of Azaspiracid-3". The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461310628.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Jauffrais, Thierry. "Ecophysiologie des dinoflagellés du genre Azadinium, production toxinique et transfert trophique vers les mollusques bivalves". Nantes, 2012. http://archive.bu.univ-nantes.fr/pollux/show.action?id=040c4b77-66f9-4f28-b05d-261282d9575f.

Texto completo
Resumen
Cette thèse a été menée pour développer une méthode d’analyse et de production des azaspiracides (AZA) à partir de cultures d’A. Spinosum. Elle a aussi eu pour objectif l’étude des facteurs environnementaux et nutritionnels influant sur la croissance et la production toxinique d’A. Spinosum. La mise en évidence du lien entre cet organisme et l'accumulation d’AZA dans les moules, ainsi que la clarification des processus d’accumulation, de détoxification et de biotransformation des AZA dans les moules a par ailleurs été réalisée. Les travaux réalisés sur l’analyse des AZA ont permis de définir une procédure d’analyse fiable qui limite notamment la formation d’artéfacts (esters méthyliques d’AZA). Cette étude a permis d’expliquer la formation des AZA méthylés, de déterminer leur structure et de proposer des solutions pour minimiser la formation de ces composés. Ce travail a aussi démontré la faisabilité d’une production durable d’AZA à partir de cultures d’A. Spinosum et a mis en évidence les principaux facteurs influant sur la croissance d’A. Spinosum et sur la production toxinique. Des expériences de contamination sur des moules ont ensuite été réalisées et ont démontré, pour la première fois, le lien directe entre A. Spinosum et l’accumulation des AZA par les moules. Cette accumulation des toxines est très rapide et atteint des concentrations en AZA qui se situent au-delà du seuil réglementaire après seulement 6 h d’exposition. Ces expériences ont aussi montré une rapide biotransformation des AZA dans les moules. Elles ont par ailleurs clarifié les cinétiques d’apparition des différents analogues d’AZA et ont montré que la détoxification des AZA est bi-phasique. Deux dernières études ont mis en évidence, d’une part, l’effet négatif d’A. Spinosum sur l’activité alimentaire des moules, et, d’autre part, la capacité des moules à accumuler les AZA présents dans le milieu sous formes dissoute ou particulaire
This study has been conducted in order to develop the analysis of AZAs and to produce AZAs from A. Spinosum culture. It also aimed at studying the effect of environmental and nutritional factors on growth and toxin production. The study also demonstrated a link between A. Spinosum and the accumulation of AZAs in shellfish, followed by the clarification of the processes of accumulation, detoxification and biotransformation of AZAs into mussels. A quantitative analysis of AZAs in A. Spinosum cultures was developed, and the formation and structure of the AZA methylated analogues was explained and minimised. This work also demonstrated the feasibility of a sustainable production of AZAs from A. Spinosum culture and highlighted the main factors influencing growth and toxin production of A. Spinosum. Using these results, mussel contaminations were performed and demonstrated for the first time the direct link between A. Spinosum and AZA accumulation into mussels. Furthermore, a rapid AZA accumulation above the regulatory limit was observed within 6 h of exposure. These experiments also highlighted the rapid biotransformation of AZA into analogues in shellfish and clarified their kinetics of appearance. Consequently, AZA biotransformation pathways were proposed for different AZA analogues. AZA detoxification was also studied and showed a detoxification with two compartments. Finally, two recent studies demonstrated the negative effect of A. Spinosum on the feeding activity of mussels as well as the ability of mussels to accumulate AZA from dissolved or particulate forms
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Kuiper, Damien L. "Studies toward the total synthesis of azaspiracid-1 /". 2010. http://hdl.handle.net/1957/14311.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.

Capítulos de libros sobre el tema "Azaspiracidi"

1

Hess, Philipp, Michael J. Twiner, Jane Kilcoyne y Silvio Sosa. "Azaspiracid Toxins: Toxicological Profile". En Marine and Freshwater Toxins, 169–91. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-6419-4_20.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Hess, Philipp, Michael J. Twiner, Jane Kilcoyne y Silvio Sosa. "Azaspiracid Toxins: Toxicological Profile". En Marine and Freshwater Toxins, 1–19. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-6650-1_20-1.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Jauffrais, T., V. Séchet, P. Truquet, Zouher Amzil, C. Herrenknecht y P. Hess. "Effect of Dilution Rate on Azadinium spinosum and Azaspiracid (AZA) Production in Pilot Scale Photobioreactors for the Harvest of AZA1 and -2". En Molluscan Shellfish Safety, 197–204. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6588-7_17.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Garcia Fern√°ndez, Javier, Daniel O‚ÄôDriscoll, Ambrose Furey y Kevin James. "Azaspiracids". En Seafood and Freshwater Toxins, 763–73. CRC Press, 2008. http://dx.doi.org/10.1201/9781420007541.ch35.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Ito, Emiko. "Toxicology of Azaspiracid-1". En Seafood and Freshwater Toxins, 775–84. CRC Press, 2008. http://dx.doi.org/10.1201/9781420007541.ch36.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

"Azaspiracids: Chemistry, Bioconversion, and Determination". En Seafood and Freshwater Toxins, 781–92. CRC Press, 2008. http://dx.doi.org/10.1201/9781420007541-57.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Hess, Philipp, Pearse McCarron, Bernd Krock, Jane Kilcoyne y Christopher O. Miles. "Azaspiracids: Chemistry, Biosynthesis, Metabolism, and Detection". En Seafood and Freshwater Toxins, 799–822. CRC Press, 2014. http://dx.doi.org/10.1201/b16662-27.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Twiner, Michael J., Philipp Hess y Gregory J. Doucette. "Azaspiracids: Toxicology, Pharmacology, and Risk Assessment". En Seafood and Freshwater Toxins, 823–56. CRC Press, 2014. http://dx.doi.org/10.1201/b16662-28.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

"Pharmacology and Epidemiological Impact of Azaspiracids". En Seafood and Freshwater Toxins, 773–80. CRC Press, 2008. http://dx.doi.org/10.1201/9781420007541-56.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Ryan, Gavin, Kevin Cunningham y Michael Ryan. "Pharmacology and Epidemiological Impact of Azaspiracids". En Seafood and Freshwater Toxins, 755–61. CRC Press, 2008. http://dx.doi.org/10.1201/9781420007541.pt11.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.

Actas de conferencias sobre el tema "Azaspiracidi"

1

Vale, Carmen, Andrea Boente-Juncal, Sandra Raposo-García, Celia Costas, M. Carmen Louzao, Paz Otero y Luis Botana. "Activation of anion channels in human cells after long term exposure to the marine toxin azaspiracid". En 1st International Electronic Conference on Toxins. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/iect2021-09114.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
También puede estar interesado en las bibliografías ampliadas sobre el tema "Azaspiracidi" para tipos de fuentes particulares:
Artículos de revistas
Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!

Pasar a la bibliografía