Literatura académica sobre el tema "Aza-lignans"
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Artículos de revistas sobre el tema "Aza-lignans"
Florent, Jean-Claude, Emmanuel Bertounesque, Matthieu Dorbec, Claude Monneret y Marie-Noëlle Rager. "Synthesis of γ-Lactam Lignans via Aza-Michael Addition". Synlett, n.º 4 (2006): 0591–94. http://dx.doi.org/10.1055/s-2006-932485.
Texto completoBarker, David, Benjamin Dickson, Nora Dittrich y Claire E. Rye. "An acyl-Claisen approach to the synthesis of lignans and substituted pyrroles". Pure and Applied Chemistry 84, n.º 7 (25 de marzo de 2012): 1557–65. http://dx.doi.org/10.1351/pac-con-11-09-27.
Texto completoOurhzif, El‐Mahdi, Arnaud Pâris, Isabelle Abrunhosa‐Thomas, El Mostafa Ketatni, Pierre Chalard, Mostafa Khouili, Richard Daniellou, Yves Troin y Mohamed Akssira. "Design, synthesis, and evaluation of cytotoxic activities of arylnaphthalene lignans and aza‐analogs". Archiv der Pharmazie 354, n.º 6 (15 de febrero de 2021): 2000479. http://dx.doi.org/10.1002/ardp.202000479.
Texto completoHitotsuyanagi, Yukio, Masatsugu Kobayashi, Masamoto Fukuyo, Koichi Takeya y Hideji Itokawa. "A facile synthesis of the 4-aza-analogs of 1-arylnaphthalene lignans chinensin, justicidin B, and Taiwanin C". Tetrahedron Letters 38, n.º 48 (diciembre de 1997): 8295–96. http://dx.doi.org/10.1016/s0040-4039(97)10204-0.
Texto completoHITOTSUYANAGI, Y., M. KOBAYASHI, M. FUKUYO, K. TAKEYA y H. ITOKAWA. "ChemInform Abstract: A Facile Synthesis of the 4-Aza-Analogues of 1-Arylnaphthalene Lignans Chinensin, Justicidin B, and Taiwanin C." ChemInform 29, n.º 7 (24 de junio de 2010): no. http://dx.doi.org/10.1002/chin.199807171.
Texto completoDorbec, Matthieu, Jean-Claude Florent, Claude Monneret, Marie-Noelle Rager y Emmanuel Bertounesque. "Synthesis of γ-Lactam Lignans via Aza-Michael Addition." ChemInform 37, n.º 28 (11 de julio de 2006). http://dx.doi.org/10.1002/chin.200628207.
Texto completoXiang, Jia-Chen, Cédric Fung, Qian Wang y Jieping Zhu. "Taming the radical cation intermediate enabled one-step access to structurally diverse lignans". Nature Communications 13, n.º 1 (16 de junio de 2022). http://dx.doi.org/10.1038/s41467-022-31000-4.
Texto completoTesis sobre el tema "Aza-lignans"
Ourhzif, El-Mahdi. "Synthèse et évaluation pharmacologique de composés originaux de la famille des méthoxynaphtalènes et lignanes arylnaphtalènes à visée antitumorale". Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2022. http://www.theses.fr/2022UCFAC016.
Texto completoBreast cancer is the most common malignant tumor in women, and the first in terms of incidence (2.1 million new cases worldwide in 2018). An increasing problem is the resistance of some cancer cells to different treatments. Due to its major impact on the population, this disease represents a critical public health problem that requires additional research at the molecular level in order to define specific therapies. The plant kingdom remains an essential source for many researchers in order to find new biologically active molecules, which can lead to the discovery of active ingredients. It is in this approach that the work carried out by our research group, in the field of the extraction and synthesis of analgesic and anticancer substances from plants used in traditional pharmacopoeia, led us to consider serial pharmacomodulations on analogues of « Guieranone A », a natural molecule isolated from the leaves of the Guiera senegalensis plant which is widely used in traditional African medicine for its therapeutic properties and which has remarkable antiproliferative activities on various tumor lines and in particular on breast cancer (MCF-7 hormone-dependent line, IC50 = 3.42 ± 0.090 µM). We have therefore developed a synthetic approach using 3,4-dimethoxy benzaldehyde as a starting material and involving Stobbe and Wittig-Horner-Emmons reactions. The synthetic reactions developed on this basis, as well as the molecules prepared, have opened a synthetic route to lignans and aza-lignans, compounds of biological and / or pharmacological interest well represented in many aromatic and medicinal plants (AMP), of the genus Justicia and Vitex. By this way, Justicidin C, Cilinaphthalide B, and Methoxy-vitedoamine A were prepared via a chloroformylation reaction followed by a Suzuki-Miyaura coupling reaction