Tesis sobre el tema "AUTOANTIGENS OF HUMANS"
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KOTHARI, VANSHIKA. "IN SILICO PREDICTION OF EPITOPES OF COMMENSAL VIRUS THAT CROSS-REACT WITH HUMAN AUTOANTIGENS". Thesis, DELHI TECHNOLOGICAL UNIVERSITY, 2021. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18394.
Texto completoIwobi, Mabel Uzoamaka. "Salivary autoantigens in human rheumatic diseases". Thesis, University of Sussex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260048.
Texto completoZhu, Jianhui. "Induction of the cellular expression of human Ro autoantigens". Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39900.
Texto completoWhitehead, Clark Merrill. "The identification and characterization of two human autoantigens, HsEg5 and ASE-1". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0027/NQ49554.pdf.
Texto completoSchirmer, Jan Henrik [Verfasser] y Friedrich [Akademischer Betreuer] Haag. "Charakterisierung putativer humaner Autoantigene / Jan Henrik Schirmer. Betreuer: Friedrich Haag". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2012. http://d-nb.info/1025150910/34.
Texto completoPurdy, Lisa Eileen. "Establishing a framework for mapping DQ8 restricted T cell epitopes for human diabetes autoantigens". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq22657.pdf.
Texto completoBarbar, Élie. "Caractérisation de RoBP1, nouveau partenaire cellulaire des ribonucléprotéines Ro humaines et autoantigène potentiel dans des maladies autoimmune". Sherbrooke : Université de Sherbrooke, 2000.
Buscar texto completoYaciuk, Jane Cherie. "Mechanisms of T cell tolerance to the RNA-binding nuclear autoantigen human La/SS-B". Oklahoma City : [s.n.], 2008.
Buscar texto completoHasler, Daniele [Verfasser] y Gunter [Akademischer Betreuer] Meister. "The Role of the Lupus Autoantigen La in the Human MicroRNA Pathway / Daniele Hasler ; Betreuer: Gunter Meister". Regensburg : Universitätsbibliothek Regensburg, 2019. http://d-nb.info/1180719557/34.
Texto completoKoelsch, Kristi Ann. "Insights into the regulation of human B cell tolerance by analysis of the immunoglobulin repertroire". Oklahoma City : [s.n.], 2009.
Buscar texto completoHaley, Joanna Dawn. "An investigation of the binding of human monoclonal antibodies to autoantigens by the modification and expression of cloned autoantibody cDNA". Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407228.
Texto completoMunro, Sandra Bronwen. "Characterization of a composite cDNA clone encoding mouse testicular N-Cadherin and the mouse homologue of a human breast tumor autoantigen". Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69645.
Texto completoThe cadherins, the influenza strain A hemagglutinins, and the fibroblast growth factor receptors are three different families of integral membrane glycoproteins that harbour the amino acid motif histidine-alanine-valine (HAV) in regions involved in protein-protein interactions. In order to identify other proteins that possess the HAV motif in functionally important regions, the SwissProt database was searched using a consensus sequence derived from the cadherins, influenza strain A hemagglutinins, and fibroblast growth factor receptors. This search identified the $ alpha$ chains of the HLA class I histocompatibility antigens as a fourth family of integral membrane glycoproteins with an HAV-containing region that is involved in a protein-protein interaction. (Abstract shortened by UMI.)
Barbar, Élie. "Caractérisation de RoBP1, nouveau partenaire cellulaire des ribonucléoprotéines Ro humaines et autoantigène potentiel dans des maladies autoimmunes". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0021/MQ61703.pdf.
Texto completoBarbar, Élie. "Caractérisation de RoBP1, nouveau partenaire cellulaire des ribonucléprotéines Ro humaines et autoantigène potentiel dans des maladies autoimmune". Mémoire, Université de Sherbrooke, 2000. http://savoirs.usherbrooke.ca/handle/11143/3204.
Texto completoLeung, Man Ching. "Identification of human hair follicle antigens targeted in the presumptive autoimmune hair follicle disorder Alopecia Areata and their potential functional relevance In Vitro. Methods development for isolation and identification of Alopecia Areata-relevant human hair follicle antigens using a proteomics approach and their functional assessment using an Ex Vivo hair follicle organ culture model". Thesis, University of Bradford, 2008. http://hdl.handle.net/10454/4330.
Texto completoMustafa, Mohammad Zahid. "Autoantibody signatures defined by serological proteome analysis in sera of patients with cholangiocarcinoma". Phd thesis, Université Paris Sud - Paris XI, 2014. http://tel.archives-ouvertes.fr/tel-01058149.
Texto completoGamradt, Stefanie [Verfasser], Alexander [Akademischer Betreuer] Scheffold, Roland [Gutachter] Lauster y Alexander [Gutachter] Scheffold. "Ex vivo Charakterisierung von humanen Autoantigen-spezifischen CD4+ T-Zellen mit Fokus auf Multiple Sklerose / Stefanie Gamradt ; Gutachter: Roland Lauster, Alexander Scheffold ; Betreuer: Alexander Scheffold". Berlin : Technische Universität Berlin, 2017. http://d-nb.info/1156010365/34.
Texto completoGavanescu, Irina Catrinel. "Autoantibodies to Centrosomes are Diagnostic for Human Scleroderma and Can Be Induced by Experimental Mycoplasma Infection in Mice: A Dissertation". eScholarship@UMMS, 2002. https://escholarship.umassmed.edu/gsbs_diss/76.
Texto completoHostmann, Björn [Verfasser]. "Etablierung der Realtime-PCR zur Charakterisierung der Effekte von TNF-a auf die mRNA-Expression des mit kutanen Lupus-Manifestationen assoziierten Autoantigens Ro/SSA52 in humanen Keratinozyten / Björn Hostmann". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023783371/34.
Texto completoDong, Qinghan. "Caractérisation des déterminants antigéniques de la thyroglobuline humaine--Clonage et séquençage d'un autoantigène de 64kd reconnu par sera de patients atteints de maladies autoimmunitaires thyroïdiennes". Doctoral thesis, Universite Libre de Bruxelles, 1991. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213003.
Texto completoLeung, Man Ching, Chris W. Sutton, D. A. Fenton y Desmond J. Tobin. "Trichohyalin is a potential major autoantigen in human alopecia areata". 2010. http://hdl.handle.net/10454/6066.
Texto completoLI, LI-LAN y 李麗蘭. "Characterization of the 86KD nuclear protein:a subunit of human ku autoantigen". Thesis, 1991. http://ndltd.ncl.edu.tw/handle/87496577787355425855.
Texto completo國立陽明大學
微生物暨免疫學研究所
79
DNA 結合蛋白Ku(p70/p86) 最早由人類自體免疫血清鑑定出來。本論文為尋找與細胞 增生相關的核蛋白, 以靜止期及增生期的T 細胞萃胞萃取液為抗原, 篩選能識別在增 生期表現增加之分子的單株抗體, 由此獲得抗Ku86的單株抗體。進一步實驗證實, 在 制備靜止期之T 細胞萃取液時, Ku86被吞噬細胞之蛋白酵素分解, 致使抗Ku86的單株 抗體呈偽陰性而被挑選出來。在細胞周期中,Ku86 的表現量不變, 然而其在核內的分 布卻隨細胞周期呈動態變化。免疫螢光染色顯示, 在interphase時,Ku86 與deconden -sed DNA分布在相同位置, 而M-phase 時,Ku86 與chromosomal DNA 完全分開。進一 步利用nocodazole及thymidine/aphidicolin 將HeLa細胞分別同步在M phase 及G /S boundary,再培養在一般培養液中至不等時間, 做免疫螢光染色, 顯示在G /S bound -ary時,Ku86 在核仁的分布很少, 而通過G /S后, 此抗原在核仁內逐漸增加, 至S ph -ase后期或G 期, 達到最高量。Ku86會隨細胞周期之運轉, 從核質移至核仁的現象, 十分有趣, 值得進一步探討。
Knuth, Mark Warren. "Ku, a human lupus autoantigen protein, is a transcriptional activator in vitro". 1991. http://catalog.hathitrust.org/api/volumes/oclc/27465912.html.
Texto completo林亭佑. "Association between canine and human systemic lupus erythematosus and recombinant protein expression of the autoantigen hnRNP G". Thesis, 2003. http://ndltd.ncl.edu.tw/handle/29003411494066338776.
Texto completo國立中興大學
獸醫微生物學研究所
91
The goals of this study are to investigate the association between human and canine systemic lupus erythematosus (SLE), and to express the recombinant protein of heterogeneous nuclear ribonucleoprotein G (hnRNP G) that is specifically recognized by sera of SLE dogs. A total of 1503 canine sera were collected, including 66 pet dogs owned by SLE patients (the experimental E group), 402 pet dogs owned by general households (the control A group), and 1035 outpatient dogs registered in the animal hospital (the control B group). The presence of antinuclear antibodies (ANA) was determined by indirect immunofluorescence assay (IFA), and the nuclear antigens recognized by ANA were characterized by Western blot analysis. Based on the canine SLE diagnostic criteria, which were revised from the diagnostic criteria of human SLE by Chabanne in 1999, we compared the frequency of SLE in these pet dogs. Among the sera of group E, 11 were positive for ANA (16.67%), while 20 of group A (4.98%) and 39 of group B (3.77%) were ANA positive. The frequency of ANA detected among pet dogs owned by SLE patients was significantly higher than that among the two control groups (p < 0.001). Of 66 pet dogs in group E, 3 were diagnosed as canine SLE. The frequency of canine SLE in group E (4.54%) was significantly higher than that of group B (0.58% or 6/1035)(p = 0.013, odds ratio [OR]=∞)and that of group A (0% or 0/402)(p = 0.003, OR=14.4). A correlation between human and canine SLE is first established in this study. These results suggest that human and canine lupus may share a common environmental or transmissible factor. To express hnRNP G recombinant proteins, we first cloned respectively the cDNA encoding hnRNP G and the major immunodominant region of hnRNP G (hnRNP Gi). Prokaryotic expression vectors for hnRNP G and hnRNP Gi were constructed and designated as pEThnRNPG and pEThnRNPGi, respectively. Both expression vectors were introduced into Escherichia coli, and the expression of recombinant protein was determined by Western blot. Bacteria carrying pEThnRNPGi expressed a recombinant protein of 33 kDa, which is the expected molecular weight of the hnRNP Gi fusion protein.
Holdener, Martin [Verfasser]. "Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection / von Martin Holdener". 2008. http://d-nb.info/996171312/34.
Texto completoZhang, Yi-Xin y 張懿欣. "Characterization of Human DNA Topoisomerase Ⅱ as an Autoantigen Recognized by Sera of Patients with Insulin-Dependent Diabetes Mellitus". Thesis, 1996. http://ndltd.ncl.edu.tw/handle/73259187237867955823.
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