Artículos de revistas sobre el tema "AsCas12a"
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Ittiprasert, Wannaporn, Chawalit Chatupheeraphat, Victoria H. Mann, Wenhui Li, André Miller, Taiwo Ogunbayo, Kenny Tran, Yousef N. Alrefaei, Margaret Mentink-Kane y Paul J. Brindley. "RNA-Guided AsCas12a- and SpCas9-Catalyzed Knockout and Homology Directed Repair of the Omega-1 Locus of the Human Blood Fluke, Schistosoma mansoni". International Journal of Molecular Sciences 23, n.º 2 (6 de enero de 2022): 631. http://dx.doi.org/10.3390/ijms23020631.
Texto completoShebanova, Regina, Natalia Nikitchina, Nikita Shebanov, Vladimir Mekler, Konstantin Kuznedelov, Egor Ulashchik, Ruslan Vasilev et al. "Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA". Nucleic Acids Research 50, n.º 2 (24 de diciembre de 2021): 1162–73. http://dx.doi.org/10.1093/nar/gkab1227.
Texto completoPetiwala, Sakina, Apexa Modi, Tifani Anton, Erin Murphy, Sabah Kadri, Hengcheng Hu, Charles Lu, Michael J. Flister y Daniel Verduzco. "Optimization of Genomewide CRISPR Screens Using AsCas12a and Multi-Guide Arrays". CRISPR Journal 6, n.º 1 (1 de febrero de 2023): 75–82. http://dx.doi.org/10.1089/crispr.2022.0093.
Texto completoSousa, Patricia, Tusneem Janoudi, Edouard deDreuzy, Mark S. Shearman, Kate Zhang y Kai-Hsin Chang. "Preclinical Development of EDIT301, an Autologous Cell Therapy Comprising AsCas12a-RNP Modified Mobilized Peripheral Blood-CD34 + Cells for the Potential Treatment of Transfusion Dependent Beta Thalassemia". Blood 138, Supplement 1 (5 de noviembre de 2021): 1858. http://dx.doi.org/10.1182/blood-2021-149956.
Texto completoPattali, Rithu, Kaitlyn Izzo, Edward Goncz, Steven Sexton, Kevin Wasko, John Zuris, Michael Nehil et al. "191 GAPDH knock-in of high affinity CD16 in iPSC derived NK cells drives high-level expression and increased anti-tumor function". Journal for ImmunoTherapy of Cancer 9, Suppl 2 (noviembre de 2021): A203. http://dx.doi.org/10.1136/jitc-2021-sitc2021.191.
Texto completoLee Yu, Henson, Yumeng Cao, Xiao Lu y I.-Ming Hsing. "Detection of rare variant alleles using the AsCas12a double-stranded DNA trans-cleavage activity". Biosensors and Bioelectronics 189 (octubre de 2021): 113382. http://dx.doi.org/10.1016/j.bios.2021.113382.
Texto completoMarino, Nicole D., Jenny Y. Zhang, Adair L. Borges, Alexander A. Sousa, Lina M. Leon, Benjamin J. Rauch, Russell T. Walton et al. "Discovery of widespread type I and type V CRISPR-Cas inhibitors". Science 362, n.º 6411 (6 de septiembre de 2018): 240–42. http://dx.doi.org/10.1126/science.aau5174.
Texto completoYang, Zhao, Kun Zhang, Tianying Xing, Suhang Bai, Zongyi Shen, Luyao Wang, Lingzhi Wang, Zichen Zhang, Chong Li y Wei Zhang. "Application of Clustered Regularly Interspaced Short Palindromic Repeat—Cas12a System in Cancer Research and its Structural Basis". Cancer Plus 4, n.º 1 (25 de enero de 2022): 30. http://dx.doi.org/10.18063/cp.v4i1.240.
Texto completoVasilev, Ruslan, Natalia Gunitseva, Regina Shebanova, Aleksei Korzhenkov, Anna Vlaskina, Marta Evteeva, Irina Polushkina et al. "Targeted Modification of Mammalian DNA by a Novel Type V Cas12a Endonuclease from Ruminococcus bromii". International Journal of Molecular Sciences 23, n.º 16 (18 de agosto de 2022): 9289. http://dx.doi.org/10.3390/ijms23169289.
Texto completoMa, Shufeng, Xinlong Wang, Yongfei Hu, Jie Lv, Chengfang Liu, Kaitong Liao, Xiaohua Guo, Dong Wang, Ying Lin y Zhili Rong. "Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain". Nucleic Acids Research 48, n.º 18 (28 de septiembre de 2020): 10590–601. http://dx.doi.org/10.1093/nar/gkaa779.
Texto completoMurugan, Karthik, Arun S. Seetharam, Andrew J. Severin y Dipali G. Sashital. "CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects". Journal of Biological Chemistry 295, n.º 17 (11 de marzo de 2020): 5538–53. http://dx.doi.org/10.1074/jbc.ra120.012933.
Texto completoZhang, Liyang, H. Tomas Rube, Christopher A. Vakulskas, Mark A. Behlke, Harmen J. Bussemaker y Miles A. Pufall. "Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes". Nucleic Acids Research 48, n.º 9 (21 de abril de 2020): 5037–53. http://dx.doi.org/10.1093/nar/gkaa231.
Texto completoWettengel, Jochen M., Lea Hansen-Palmus, Sofiya Yusova, Lauren Rust, Sreya Biswas, Julien Carson, Junghyun Ryu, Benjamin N. Bimber, Jon D. Hennebold y Benjamin J. Burwitz. "A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing". International Journal of Molecular Sciences 24, n.º 9 (5 de mayo de 2023): 8271. http://dx.doi.org/10.3390/ijms24098271.
Texto completoAllen, Alexander G., Samia Q. Khan, Kaitlyn M. Izzo, Mrunali Jagdale, Alexandra Gerew, Nadire R. Cochran, Jared Getgano et al. "Abstract 562: AsCas12a gene-edited iPSC-derived NK cells constitutively expressing CD16 and membrane-bound IL-15 demonstrate prolonged persistence and robust anti-tumor activities in a solid tumor mouse model". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 562. http://dx.doi.org/10.1158/1538-7445.am2022-562.
Texto completoZhu, Dan, Junyi Wang, Di Yang, Jianzhong Xi y Juan Li. "High-Throughput Profiling of Cas12a Orthologues and Engineered Variants for Enhanced Genome Editing Activity". International Journal of Molecular Sciences 22, n.º 24 (10 de diciembre de 2021): 13301. http://dx.doi.org/10.3390/ijms222413301.
Texto completoHanna, Rabi, Haydar Frangoul, Christopher Mckinney, Luis Pineiro, Markus Mapara, Kai-Hsin Chang, Michael Jaskolka et al. "S264: EDIT-301 SHOWS PROMISING PRELIMINARY SAFETY AND EFFICACY RESULTS IN THE PHASE I/II CLINICAL TRIAL (RUBY) OF PATIENTS WITH SEVERE SICKLE CELL DISEASE USING HIGHLY SPECIFIC AND EFFICIENT ASCAS12A ENZYME". HemaSphere 7 (agosto de 2023): e05170e0. http://dx.doi.org/10.1097/01.hs9.0000967968.05170.e0.
Texto completoGerew, Alexandra, Steven Sexton, Kevin M. Wasko, Mark S. Shearman, Kate Zhang, Kai-Hsin Chang y Samia Q. Khan. "Deletion of CISH and TGFβR2 in iPSC-Derived NK Cells Promotes High Cytotoxicity and Enhances In Vivo Tumor Killing". Blood 138, Supplement 1 (5 de noviembre de 2021): 2780. http://dx.doi.org/10.1182/blood-2021-150731.
Texto completoMaerken, Melanie, David MacEwan, Nicholas Harper, Joseph R. Slupsky y Adam Linley. "Gene Editing of BTK in Acute Myeloid Leukaemia Using CRISPR-Cas9". Blood 132, Supplement 1 (29 de noviembre de 2018): 3952. http://dx.doi.org/10.1182/blood-2018-99-113804.
Texto completoAllen, Alexander G., Rithu Pattali, Kaitlyn M. Izzo, Jared A. Getgano, Kevin M. Wasko, Laura C. Blaha, John A. Zuris, Kate Zhang, Mark S. Shearman y Kai-Hsin Chang. "A Bicistronic Vector Expressing CD16 and a Membrane Bound IL-15 Construct in iPSC Derived NK Cells Increased Cytotoxicity and Persistence". Blood 138, Supplement 1 (5 de noviembre de 2021): 4809. http://dx.doi.org/10.1182/blood-2021-153258.
Texto completoCetin, Ronay, Martin Wegner, Leah Luwisch, Sarada Saud, Tatjana Achmedov, Sebastian Süsser, Antonella Vera-Guapi et al. "Optimized metrics for orthogonal combinatorial CRISPR screens". Scientific Reports 13, n.º 1 (6 de mayo de 2023). http://dx.doi.org/10.1038/s41598-023-34597-8.
Texto completoJacobsen, Thomas, Chunyu Liao y Chase L. Beisel. "The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs". FEMS Microbiology Letters 366, n.º 8 (1 de abril de 2019). http://dx.doi.org/10.1093/femsle/fnz085.
Texto completoZhang, Liyang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube et al. "AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines". Nature Communications 12, n.º 1 (23 de junio de 2021). http://dx.doi.org/10.1038/s41467-021-24017-8.
Texto completoZhang, Yingxiao, Yanhao Cheng, Hong Fang, Nathaniel Roberts, Liyang Zhang, Christopher A. Vakulskas, Randall P. Niedz, James N. Culver y Yiping Qi. "Highly Efficient Genome Editing in Plant Protoplasts by Ribonucleoprotein Delivery of CRISPR-Cas12a Nucleases". Frontiers in Genome Editing 4 (31 de enero de 2022). http://dx.doi.org/10.3389/fgeed.2022.780238.
Texto completoAn, Yi, Ya Geng, Junguang Yao, Chunxiang Fu, Mengzhu Lu, Chun Wang y Juan Du. "Efficient Genome Editing in Populus Using CRISPR/Cas12a". Frontiers in Plant Science 11 (19 de noviembre de 2020). http://dx.doi.org/10.3389/fpls.2020.593938.
Texto completoZhu, Zhijian, Manyu Zhang, Dandan Liu, Defei Liu, Tao Sun, Yujing Yang, Jiacheng Dong et al. "Development of the thermophilic fungus Myceliophthora thermophila into glucoamylase hyperproduction system via the metabolic engineering using improved AsCas12a variants". Microbial Cell Factories 22, n.º 1 (11 de agosto de 2023). http://dx.doi.org/10.1186/s12934-023-02149-4.
Texto completoKrishnamurthy, Sateesh, Christine Wohlford-Lenane, Suhas Kandimalla, Gilles Sartre, David K. Meyerholz, Vanessa Théberge, Stéphanie Hallée et al. "Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia". Nature Communications 10, n.º 1 (28 de octubre de 2019). http://dx.doi.org/10.1038/s41467-019-12922-y.
Texto completoMaule, Giulia, Antonio Casini, Claudia Montagna, Anabela S. Ramalho, Kris De Boeck, Zeger Debyser, Marianne S. Carlon, Gianluca Petris y Anna Cereseto. "Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing". Nature Communications 10, n.º 1 (7 de agosto de 2019). http://dx.doi.org/10.1038/s41467-019-11454-9.
Texto completoIlla-Berenguer, Eudald, Peter R. LaFayette y Wayne A. Parrott. "Editing efficiencies with Cas9 orthologs, Cas12a endonucleases, and temperature in rice". Frontiers in Genome Editing 5 (17 de marzo de 2023). http://dx.doi.org/10.3389/fgeed.2023.1074641.
Texto completoDeWeirdt, Peter C., Kendall R. Sanson, Annabel K. Sangree, Mudra Hegde, Ruth E. Hanna, Marissa N. Feeley, Audrey L. Griffith et al. "Optimization of AsCas12a for combinatorial genetic screens in human cells". Nature Biotechnology, 13 de julio de 2020. http://dx.doi.org/10.1038/s41587-020-0600-6.
Texto completoOkada, Satoshi, Goro Doi, Shitomi Nakagawa, Emiko Kusumoto y Takashi Ito. "Simple-to-use CRISPR-SpCas9/SaCas9/AsCas12a vector series for genome editing in Saccharomyces cerevisiae". G3 Genes|Genomes|Genetics, 30 de agosto de 2021. http://dx.doi.org/10.1093/g3journal/jkab304.
Texto completoZhang, Liyang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube et al. "Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines". Nature Communications 12, n.º 1 (19 de julio de 2021). http://dx.doi.org/10.1038/s41467-021-24770-w.
Texto completoMaule, Giulia, Antonio Casini, Claudia Montagna, Anabela S. Ramalho, Kris De Boeck, Zeger Debyser, Marianne S. Carlon, Gianluca Petris y Anna Cereseto. "Author Correction: Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing". Nature Communications 11, n.º 1 (22 de octubre de 2020). http://dx.doi.org/10.1038/s41467-020-19351-2.
Texto completoKnott, Gavin J., Brady F. Cress, Jun-Jie Liu, Brittney W. Thornton, Rachel J. Lew, Basem Al-Shayeb, Daniel J. Rosenberg et al. "Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a". eLife 8 (9 de agosto de 2019). http://dx.doi.org/10.7554/elife.49110.
Texto completoAgeely, Eman A., Ramadevi Chilamkurthy, Sunit Jana, Leonora Abdullahu, Daniel O’Reilly, Philip J. Jensik, Masad J. Damha y Keith T. Gagnon. "Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles". Nature Communications 12, n.º 1 (15 de noviembre de 2021). http://dx.doi.org/10.1038/s41467-021-26989-z.
Texto completoWang, Yao, Tao Qi, Jingtong Liu, Yuan Yang, Ziwen Wang, Ying Wang, Tianyi Wang et al. "A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing". Science Advances 9, n.º 6 (10 de febrero de 2023). http://dx.doi.org/10.1126/sciadv.abo6405.
Texto completoOoi, Kean Hean, Mengying Mandy Liu, Jie Wen Douglas Tay, Seok Yee Teo, Pornchai Kaewsapsak, Shengyang Jin, Chun Kiat Lee et al. "An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing". Nature Communications 12, n.º 1 (19 de marzo de 2021). http://dx.doi.org/10.1038/s41467-021-21996-6.
Texto completoKim, Do Yon, Jeong Mi Lee, Su Bin Moon, Hyun Jung Chin, Seyeon Park, Youjung Lim, Daesik Kim, Taeyoung Koo, Jeong-Heon Ko y Yong-Sam Kim. "Efficient CRISPR editing with a hypercompact Cas12f1 and engineered guide RNAs delivered by adeno-associated virus". Nature Biotechnology, 2 de septiembre de 2021. http://dx.doi.org/10.1038/s41587-021-01009-z.
Texto completoSun, Ruirui, Yuqian Zhao, Wenjuan Wang, Jun-Jie Gogo Liu y Chunlai Chen. "Nonspecific interactions between Cas12a and dsDNA located downstream of the PAM mediate target search and assist AsCas12a for DNA cleavage". Chemical Science, 2023. http://dx.doi.org/10.1039/d2sc05463a.
Texto completoBanakar, Raviraj, Mollie Schubert, Gavin Kurgan, Krishan Mohan Rai, Sarah F. Beaudoin, Michael A. Collingwood, Christopher A. Vakulskas, Kan Wang y Feng Zhang. "Efficiency, Specificity and Temperature Sensitivity of Cas9 and Cas12a RNPs for DNA-free Genome Editing in Plants". Frontiers in Genome Editing 3 (12 de enero de 2022). http://dx.doi.org/10.3389/fgeed.2021.760820.
Texto completoWang, Yanchun, Shuli Sang, Xin Zhang, Haoxia Tao, Qing Guan y Chunjie Liu. "Efficient Genome Editing by a Miniature CRISPR-AsCas12f1 Nuclease in Bacillus anthracis". Frontiers in Bioengineering and Biotechnology 9 (14 de enero de 2022). http://dx.doi.org/10.3389/fbioe.2021.825493.
Texto completoBigelyte, Greta, Joshua K. Young, Tautvydas Karvelis, Karolina Budre, Rimante Zedaveinyte, Vesna Djukanovic, Elizabeth Van Ginkel et al. "Miniature type V-F CRISPR-Cas nucleases enable targeted DNA modification in cells". Nature Communications 12, n.º 1 (26 de octubre de 2021). http://dx.doi.org/10.1038/s41467-021-26469-4.
Texto completoHuang, Hongxin, Weiqi Lv, Jinhe Li, Guanjie Huang, Zhihong Tan, Yongfei Hu, Shufeng Ma, Xin Zhang, Linxuan Huang y Ying Lin. "Comparison of DNA targeting CRISPR editors in human cells". Cell & Bioscience 13, n.º 1 (16 de enero de 2023). http://dx.doi.org/10.1186/s13578-023-00958-z.
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