Tesis sobre el tema "Anxiété – Physiologie"
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Mombereau, Cédric. "Etude du rôle des récepteurs GABA dans l'anxiété, la dépression et l'addiction : approche pharmacologique et génétique". Bordeaux 1, 2006. http://www.theses.fr/2006BOR13139.
Texto completoLe, Merrer Julie. "Opium, opiacés, opioi͏̈des : du remède millénaire à la physiologie des morphines endogènes". Bordeaux 2, 2000. http://www.theses.fr/2000BOR2P106.
Texto completoPelloux, Yann. "Prédispositions aux toxicomanies : influence de la recherche de nouveauté, de l'anxiété et de la dépression sur la vulnérabilité à différents agents toxicomanogènes". Rouen, 2003. http://www.theses.fr/2003ROUES043.
Texto completoIt is the commonly accepted that a wide variability exists in susceptibility to drug of abuse, both in human and non-human animals. Some personality trait and pathological behaviours are frequently associated with drug addiction. For example, novelty seeking is often observed in drug abuser, and anxious and depressive individuals also frequently abuse drugs. The purpose of this investigation was to examine the respective influence of these factors on the vulnerability to drug addiction. In the first phase, we compared the influence of responses to both forced and free-choice novelty within a population of Wistar rats. The reactivity to forced novelty was associated with a higher sensitivity to the rewarding effects of a low dose of amphetamine and with a lower oral consumption of amphetamine, morphine and sucrose. . In the second phase, we compared the influences of anxiety and helplessness on vulnerability to drug of abuse. In Wistar rats, anxiety was associated with greater conditioned place preference induced by high, but not low, doses of cocaine and amphetamine. In addition, anxiety was not associated with a greater consumption of a low concentration of amphetamine solutions, but anxious animals consumed less of a higher concentration of amphetamine solution than non-anxious animals Similar to anxiety, helplessness was not associated to any difference in drug sensitivity Taken together these results suggest that responses to novelty, anxiety and helplessness are associated with different aspects of vulnerability to drugs of abuse
Vignet, Caroline. "Altération de la physiologie des poissons exposés à des hydrocarbures aromatiques polycycliques (HAP) : comportement et reproduction". Thesis, La Rochelle, 2014. http://www.theses.fr/2014LAROS003/document.
Texto completoPolycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants (POPs) which are found in complex mixtures in the environment including aquatic ecosystems. They adsorb on particles, accumulate in sediment and in the first link of the food web. The aim of this study was to measure long term effects of PAHs contamination on a vertebrate model : the zebrafish. In a first study, embryos were exposed on natural sediment spiked with 3 individual PAH (phenanthrene, pyrene and benzo[a]pyrene) during the first four days of their development. In a second study, to evaluate the consequences of long-term chronic exposure to PAHs, zebrafish were exposed, from their first meal (5 days post fertilisation) until they became reproducing adults, to diets spiked with three PAHs fractions at environmentally relevant concentrations (0.3X, 1X and 3X; with the 1X concentration being in the range of 4.6-6.7 μg.g-1 for total quantified PAHs). The fractions used were representative of PAHs of pyrolytic (PY) origin or of two different oils of differing compositions (a heavy fuel (HO) and a light crude oil (LO)). Long term effects on growth, survival, reproduction and behavior were evaluated at different ages. Effects were observed at molecule, tissue, organ and individual scales. In general, for contaminated fish, growth was reduced, larval survival decreased in HO, and reproduction was strongly impaired at hormonal, tissue and phenotypic levels, and behavioral responses were lethargic or hyperactive depending on fractions and stages. Sediment exposure still revealed visible effects when fish were 6 month old. These results hereby showed significant late effects, especially in behavioral responses after an early exposure, including in larvae issued from contaminated fish. In spiked diets contaminated fish, we observed a gradation of effects. Combining all functions, we established of hierarchy in toxicity in the studied fractions: PY < LO ≈ HO. Finally, our results gathered at a multiscale from molecule, to tissue and individuals, indicate that PAH mixtures of different compositions, representative of situations encountered in the wild, can promote lethal and sublethal effects which are likely to be detrimental for fish survival and recruitment into future generations
Comte, Magali. "Neuro-imagerie fonctionnelle du circuit cortico-limbique lors du traitement émotionnel chez le patient schizophrène et le volontaire sain". Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5071/document.
Texto completoWithin the cortico-limbic circuit, complementary regions are believed to be involved in either the appraisal or the regulation of affective state. However, the respective contribution of these bottom-up and top-down mechanisms during emotion processing remains to be clarified. First, we validated a new fMRI paradigm designed to dissociate the components of the cortico-limbic circuit, that is, the dorsal cognitive circuit intertwined with the ventral affective circuit. We found that the amygdala and its connections to the dorsal circuit was engaged by bottom-up emotional processing. The dorsal anterior cingulate cortex (ACC) and its connections to the dorsolateral prefrontal cortex (DLPFC) and amygdala, was recruited by top-down resolution of emotional conflict. The DLPFC and its connections to dorsal ACC was engaged by top-down attentional control. Secondly, we investigated the impact of anxiety on the circuit. We demonstrated that higher levels of anxiety were associated with stronger conflict-related activation in ACC but with reduced connectivity between ACC and LPFC. Finally, we examined the variation in functional activity and connectivity in schizophrenia patients. In patients compared to controls, bottom-up processes were associated with reduced functional interaction between the amygdala and both dorsal and ventral ACC as well as DLPFC. Top-down resolution of emotional conflict led to stronger functional connectivity between the dorsal ACC and both ventral parts of ACC and DLPFC. Increased top-down attentional control caused higher functional coupling between the DLPFC and ventral ACC
Cohen, Candie. "Rôle du noyau subthalamique dans les processus motivationnels et la dépendance à la cocaïne". Toulouse 3, 2013. http://thesesups.ups-tlse.fr/3441/.
Texto completoThe mesolimbic circuit has long been implicated in cocaine addiction since this drug directly increases dopaminergic transmission from ventral tegmental area (VTA) to ventral striatum. The subthalamic nucleus (STN) is well known for its role in motor processes (working as a relay for basal ganglia pathways). In addition, it might be a part of the mesolimbic circuit as it is branched to limbic structures such as ventral pallidum or prefrontal cortex. Moreover, inactivating the STN by lesion or high frequency stimulation (HFS) decreases compulsive behaviors and incentive motivation for cocaine (assessed in conditioned place preference (CPP) paradigm and in the progressive ratio test). In contrast it increases the motivation for natural reward. This opposite effect lead to the hypothesis that STN could be a target to cure cocaine addiction, since the goal to treat cocaine addiction is to decrease the motivation for the drug without diminishing motivation for natural rewards. However, rats tested in those experiments were deprived when tested for food motivation while they were not when tested for cocaine motivation. Thus, in order to control deprivation condition, we have tested whether or not rats feed ad libitum would still show enhanced motivation for food. We have shown that the effect of STN lesion on food motivation is independent of feeding condition. A second experiment using dopaminergic depletion allowed to show that the effects of STN HFS on motivation for cocaine and food are differentially modulated by the nigrostriatal pathway integrity. Preliminary results revealed that reduced motivation for cocaine after STN HFS is independent of the nigrostriatal pathway integrity. In contrast, increased motivation for food after STN HFS seems to depend of dopaminergic system integrity. Moreover, surprisingly, we show that lesioning the nigrostriatal pathway enhanced incentive motivation for food but had no effect on incentive motivation for cocaine as measured in the CPP paradigm. These results support the idea that motivation for food vs. Cocaine recruit different circuits. To test the hypothesis that STN could be a target to treat cocaine addiction, we also examined whether or not lesioning the STN can have preventative or curative effects on escalation of cocaine intake while rats are exposed in long-access (6h) self-administration sessions. We have shown that STN lesions prevent escalation of cocaine consumption. In addition, we have also shown that STN lesions decrease consumption in animals that have escalated in their cocaine intake, thus validating a curative effect of the STN lesion. Since cocaine can have anxiogenic effects, we wondered whether these effects could have been potentiated by the STN lesion to reduce the visits to the environment paired with cocaine in the CPP experiments. To address this issue, we have tested the effect of STN lesion on anxiety induced by cocaine, using an elevated plus maze. No effect of STN lesion was found after one cocaine injection (10mg/kg i. P. ). However, after four injections of cocaine (mimicking the CPP schedule), STN lesioned rats showed a decrease of the number of entries in the different parts of the maze, while the controls showed an increase of this number. In addition, while exploration of open arms was reduced in time in the control group, it was not in STN rats. Those results suggest that lesioning the STN could not have increased the anxiogenic effect of the drug, but could have increased its psychomotor effect. In conclusion, my thesis evidences a role for STN in opponent processes serving to decrease psychomotor effect of the cocaine after prolonged administration. This is in accordance with anatomo- functional placement of the STN in basal ganglia circuitry, as STN is the sole nucleus able to counteract output structure desinhibition induced by the increased of dopamine flux during cocaine binge
Handouzi, Wahida. "Traitement d'information mono-source pour la validation objective d'un modèle d'anxiété : application au signal de pression sanguine volumique". Electronic Thesis or Diss., Université de Lorraine, 2014. http://www.theses.fr/2014LORR0237.
Texto completoDetection and evaluation of emotions are areas of great interest in many communities both in terms of human and exact sciences. In this thesis we focus on social anxiety recognition, which is an irrational fear felt by a person during any form of social relationship. Anxiety can be revealed by a set of physical and physiological traits such as tone of voice, facial expressions, increased heart rate, flushing ... etc. The interest to the physiological measures is motivated by them robustness to avoid the artifacts created by human social masking, they are a continuous source of data and each emotion is characterized by a particular physiological variation. In this work, we propose a measurement system based on the use of a single physiological signal "Blood volume pulse BVP". The use of a single sensor limits the subjects’ discomfort. From the BVP signal we selected three relevant features which best represents the close relationship between this signal and anxiety status. This features set is classified using support vector machine SVM. The work undertaken in the field of emotion recognition frequently use, for information support, unreliable data do not always correspond to the situations envisaged. This lack of reliability may be due to several parameters among them the subjectivity of the evaluation method used (self-evaluation questionnaire, subjects…etc.). We have developed an approach to objective assessment of data based on the dynamics of selected features. The used database was recorded in our laboratory under real conditions acquired in subjects with a level of anxiety during social situations and who are not under psychological treatment. The used stimulus is the exposition to virtual environments representing some feared social situations. After the evaluation stage, we obtained a reliable model for the recognition of two levels of anxiety. The latter was tested in a clinic specializing in cognitive behavioral therapy (CBT) on phobic subjects. The results highlight the reliability of the built model specifically for the recognition of anxiety levels in healthy subjects or of phobic subjects, what constitutes a solution to the lack of data affecting different areas of recognition
Richard, Augustin. "Implication du striatum et du pallidum ventral dans le traitement de l'information aversive : approche électrophysiologique et pharmacologique chez le primate non-humain". Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10318/document.
Texto completoStriatum and globus pallidus belong to the basal ganglia, which are a group of subcortical structures involved in motor, cognitive and motivational functions. They are also involved in the reward system which enables one’s motivation to initiate approach behaviors in order to get a reward and then consolidate activities that have produced these behaviors. This represents instrumental learning basis. However, in some situations, the behavior to be initiated depends on a motivation to escape or avoid an aversive situation. For a long time, it was thought that aversive information processing system and reward system depended on different networks and cerebral regions. Yet, a growing number of studies tend to show that basal ganglia certainly play an important role in aversive information processing. In this thesis, we recorded neuronal activity and performed local pharmacological perturbations in non-human primates, in two structures of the reward system, anterior striatum and ventral pallidum, while performing a behavioral task requiring them to initiate alternatively approach behaviors toward a reward and avoidance behaviors from an aversive event. We showed aversive information coding for the predictive stimulus, preparation and initiation of the avoidance behavior and anticipation and response to the aversive events. Furthermore, local perturbation experiments demonstrated that a functional impairment of the anterior striatum and the ventral pallidum affects the behaviors usually initiated by the animals in aversive context. Put together, these results clearly show that these two cerebral structures are involved in both appetitive and aversive motivations
Castor, Naomie. "Les déterminants de la récupération chez des patients traumatisés crâniens". Thesis, Paris 8, 2017. http://www.theses.fr/2017PA080139/document.
Texto completoNeurological pathologies are frequently considered as serious and generate cognitive disabilities irreversible. However some diseases as traumatic brain injury and stroke have a recovery potential. These pathologies are different concerning etiology and people who are suffer but similar about medical care and sequelae. The different researches related to the recovery of language disorders and prognostic variables exposure, led us to realize a longitudinal study on recovery variables on traumatic brain injury. Considering the potential recovery of stroke, we have effected a comparative research between both pathologies. Correlational analyses between depression, anxiety, self-esteem, resilience, coping, abilities cognitive, medical care and anosognosia have exposed the determinants of recovery in traumatic brain injury and stroke. The results of this study show identical cognitive performances between patients and also a recovery for both disease. Recovery was similar for patients, which means regardless pathologies, patients recover in same way
Harris, Rachel Armstrong. "Stress : the physiology and psychology of a training situation". Thesis, Robert Gordon University, 1995. http://hdl.handle.net/10059/2350.
Texto completoSchulz, Stefan M. "Mediators of Social Anxiety : External Social Threat-Cues vs. Self-Related Negative Cognitions". kostenfrei, 2009. http://nbn-resolving.de/urn/resolver.pl?urn=nbn:de:bvb:20-opus-44684.
Texto completoLepicard, Eve. "Anxiété et contôle de l'équilibre : D'un fait psychopathologique à la modélisation expérimentale chez la souris". Paris 7, 2001. http://www.theses.fr/2001PA070019.
Texto completoMismatch in the neural integration of sensory inputs can induce disturbances in space perception and balance control in human. Non-congruence between expectation and reality of sensory inputs has also been shown to possibly generating anxiety. As the underlying mechanisms of this phenomenon are still unclear, a procedure called the "rotating beam" could allow investigation in the mice. This study needed first a control of the sensorimotor abilities of the two inbred strains used in the experiment: one anxious strain, BALB/cByJ and one non anxious, C57BL/6J. The neurological assessment consisted in testing different reflexes, the vestibular function and the motor coordination. No significant difference were found between the two strains which display normal sensorimotor abilities. The same inbred strains were used in the second experiment, the "rotating beam". After a training session, 3 month-old male mice had to walk across an horizontal cylindrical metal bar to reach a platform. During the second day of test, the bar rotated with a constant velocity. Performance was assessed by the number of falls and the number of imbalances. Posture was also analysed in terms of the elevation of the body (tail excluded) relative to the beam and the position of the tai!. During the test session, number of imbalances and percentage of mice falling were higher for BALB/cByJ than in the C57BL/6J. Moreover, a striking difference in body posture between the two strains existed when the mice were on the bar. In conclusion, despite equal sensorimotor abilities, C57BL/6J and BALB/cByJ, mice have different adaptations in our "rotating beam" test. Based on two genetically-defined mouse strains, our results suggest that postural ability and balance control of the mouse are associated with anxiety
Warner, Judith Catherine. "Biology and Environment, Mothers and Infants: Linking Stress Physiology, Depression, Anxiety and Attachment". Thesis, Griffith University, 2013. http://hdl.handle.net/10072/365334.
Texto completoThesis (PhD Doctorate)
Doctor of Philosophy in Clinical Psychology (PhD ClinPsych)
School of Applied Psychology
Griffith Health
Full Text
Sanders, Ashley F. P. "Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology". ScholarWorks@UNO, 2016. http://scholarworks.uno.edu/td/2191.
Texto completoCurzon-Jones, Benjamin T. "The relationship between anxiety, gaze direction and increased falls risk in walking older adults". Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6889/.
Texto completoHolterman, Leigh Ann. "Peer Victimization and the Development of Anxiety and Depressive Symptoms: The Roles of Stress Physiology and Gender". ScholarWorks @ UVM, 2016. http://scholarworks.uvm.edu/graddis/460.
Texto completoAjibewa, Tiwaloluwa Adedamola. "Role of anxiety on vascular dysfunction". Thesis, University of Iowa, 2016. https://ir.uiowa.edu/etd/3035.
Texto completoMettrick, Jon George. "Test anxiety and coping with evaluation". CSUSB ScholarWorks, 1998. https://scholarworks.lib.csusb.edu/etd-project/1512.
Texto completoDalton, Melissa D. "EFFECTS OF SELF-DIRECTED PHYSIOLOGICAL MONITORING ON THERAPISTS ANXIETY". UKnowledge, 2012. http://uknowledge.uky.edu/hes_etds/3.
Texto completoLemay, Francis. "Anxiété, éthylisme, motivation et performance cognitive à la suite d'une réduction de la sérotonine cérébrale chez les souris mutantes TPH2". Thesis, Université Laval, 2014. http://www.theses.ulaval.ca/2014/30482/30482.pdf.
Texto completoAffective disorders such as anxiety and major depression are the most frequently diagnosed psychiatric disorders in the world. Among their potential causes are chronic stress and central nervous system dysfunctions, such as genetic mutations. A mutation in the rate limiting enzyme of brain serotonin synthesis, tryptophan hydroxylase 2, was associated with a severe form of major depression with multiple comorbidities in humans. The present thesis proposes to study the behavioral effects of this mutation in mice. In a first article, the anxiety level of mutant mice (HO) was assessed using two experimental paradigms. Their cognitive performances were also observed using a spatial learning task. Then, the anxious reactions and cognitive performances of mice were assessed following a recent restraint chronic stress which lasted two hours per day for four straight days. In a second article, their motivation to drink sucrose or quinine, as well as their preference for alcohol and their motivation for drinking it in aversive conditions were assessed. The experiments demonstrate that HO mice were more anxious and presented deficits in cognitive performances when compared to mice not carrying the mutation (WT). WT mice reacted to chronic stress by showing anxious behaviors and cognitive performances similar to those of unstressed HO mice, whereas HO were not affected by stress. The motivation of HO mice did not differ from that of WT for sucrose and quinine, and their preference for alcohol was similar. However, when the alcohol solution was mixed with quinine, making it bitter and aversive, HO mice consumed more of it than WT, suggesting a higher level of motivation for alcohol. These results reinforce the notion that the link between anxiety and alcohol consumption is modulated by serotonin and suggest that cognitive deficits observed following serotonin reduction would be partly modulated by the resulting anxiety. The implications of HO mice’s absence of response to chronic stress are also discussed.
Turri, Maria Grazia. "Mapping of behavioural quantitative trait loci". Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:89823fa1-c1d3-49e3-acb9-46da18b12245.
Texto completoRowe, Jack E. "Effect of inspiration to expiration ratio on autonomic arousal /". free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9842562.
Texto completoWillmann, Magali. "Modifications végétatives, somatiques et de l'état d'anxiété en réponse à un stress modéré : influence de caractéristiques individuelles ou situationnelles". Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0399/document.
Texto completoExposure to stressful situations is typically associated with cognitive, affective, physiological and behavioral responses. The aim of this work was to examine the affective and physiological responses to moderate stress, particularly state anxiety and muscle tension and also to consider the characteristics of the situation and the trait anxiety of the subjects.Our results showed that high anxious subjects have a higher level of state-anxiety than low anxious subjects during the stressful task, but no difference in physiological reactivity has been found between both groups. However, after exposure to the stressful situation, high anxious subjects have delayed physiological recovery. This suggests that physiological differences might emerge during the recovery period according to trait anxiety level. Thus, affective and physiological responses could depend on trait anxiety level. Furthermore, our results showed in individuals with homogeneous trait anxiety level that muscle tension induced by the stressful situation could differ depending on the muscles. This result suggests a relationship between the different muscular responses and the functional role of the muscles. Moreover, the results showed that state anxiety and these muscular responses decrease during a second exposure to the same stressful situation, except for the trapezius muscle which seems to have a particular reactivity to the stressor. However, adaptation of these muscular modifications and of state anxiety suggests that affective and muscular responses could be influenced by the characteristics of the situation (novelty and repetition).In conclusion, these findings highlight the importance of considering the environmental characteristics and the personality trait of individuals in research on stress responses
Jane, Sui-Whi. "Effects of a full-body massage on pain intensity, anxiety, and physiologic relaxation in Taiwanese patients with metastatic bone pain : a pilot study /". Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/7241.
Texto completoFrew, Ashley. "The influence of discouragement, anxiety and anger on pain : an examination of the role of endogenous opioids /". Access via Murdoch University Digital Theses Project, 2004. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20050930.111852.
Texto completoMacNeil, Glenda (Glenda Marie). "Stressor exposure and intraventricular cholecystokinin (CCK-8) administration in the light dark box model of anxiety in CD-1 mice; possible cross-sensitization". Ottawa, 1996.
Buscar texto completoDrouin-Maziade, Christine. "Influence des processus motivationnels sur la mémoire de travail chez les enfants TDA/H avec ou sans anxiété comorbide". Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26618/26618.pdf.
Texto completoDavis, Joseph E. "Interpreting direction of anxiety within Hanin's individual zone of optimal functioning /". free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9953855.
Texto completoCaldji, Christian. "Early environmental regulation of neural systems mediating fearfulness". Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103367.
Texto completoStudies with the handling paradigm have lead to the idea that variations mother-pup interactions may actually be the cause of the handling effects. As adults, the offspring of mothers which exhibited high levels of licking/grooming and arched-back nursing (LG-ABN) showed substantially reduced behavioral fearfulness in response to novelty compared to the offspring of low LG-ABN mothers. In addition, the adult offspring of the high and low LGABN mothers showed the same receptor and molecular profiles as H and NH adult offspring. Corticotropin releasing factor (CRF) and alpha2 norepinephrine receptor levels, additional receptor systems thought to be important in the expression of fearfulness, differed in these animals too. Adoption studies give further support to the maternal hypothesis in the finding that the expression mRNA for the gamma2 sub-unit of the GABAA receptor complex can be differentially expressed as a result of different offspring to mother combinations.
Taken together, these findings suggest that early life events (ie: naturally occurring differences in maternal care) during the first few days of life have long-term effects on the development of central neurotransmitter systems, which mediate the expression of fearfulness to novelty.
Fu, Chang-Chi Musetta. "Music therapy and women's health effects of music-assisted relaxation on women graduate students' stress and anxiety levels /". Diss., Connect to online resource - MSU authorized users, 2008.
Buscar texto completoHenderson, Fiona. "Régulation du sommeil et de l’anxiété par VGLUT3, le transporteur vésiculaire du glutamate de type 3". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS136.
Texto completoSleep impairment is frequently associated with psychiatric disorders such as depressive- and anxiety-disorders. However, the neuronal underlying mechanisms linking sleep and emotions remain poorly understood. Considerable attention has been devoted to serotonin (5-HT) transmission from the raphe nucleus, which takes part in modulating sleep and mood. Part of these neurons express VGLUT3, the vesicular glutamate transporter type 3, which allows 5-HT neurons to use, in addition to 5-HT, glutamate as a neurotransmitter. Our aim was to assess the role of VGLUT3 in modulating anxiety and sleep, in relation with 5-HT and to identify the underlying mechanisms. Anxiety-like behaviors and sleep/wake were characterized in several mouse models with VGLUT3 deletion in the whole brain, in the anterior raphe nuclei or in 5-HT neurons. To model the links between emotions and sleep, mutant mice underwent a psychological stress, acute restraint stress or a psychosocial stress, the chronic social defeat stress. The role of the glutamatergic signaling in 5-HT neurons was then further assessed. We used a chemogenetic approach to evaluate sleep changes triggered by activation of 5-HT neurons, with VGLUT3 deletion or not. Using the same approach, glutamatergic signaling from VGLUT3-positive neurons of the DRN was also assessed. Our results show that VGLUT3-positive neurons in the raphe 1) regulate rapid eye-movement sleep (REMS) in baseline, 2) control stress-induced hyperthermia and influence REMS changes after stress and 3) promote wake in a context-dependent manner. Thus, this study highlights a new role for VGLUT3 in the raphe nucleus in regulating sleep and stress responses
Glynn, Laura M. "The effects of social support and affiliation during the anticipation and recall of stressful events /". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9913151.
Texto completoNelligan, Julie. "Anxiety and autonomic nervous system function during stress and recovery". Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1060797984.
Texto completoTitle from first page of PDF file. Document formatted into pages; contains xiii, 127 p.; also includes graphics Includes bibliographical references (p. 91-105). Available online via OhioLINK's ETD Center
Sessford, Karus David. "The effect of anxiety on motor learning during a postural task". Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Kinesiology, c2011, 2011. http://hdl.handle.net/10133/3122.
Texto completoix, 103 leaves : ill. ; 29 cm
Larsen, Caroline y n/a. "Pheromones, prolactin and maternal behavior : (male pheromones initiate prolactin-induced neurogenesis, decrease anxiety and advance maternal behavior in virgin female mice)". University of Otago. Department of Anatomy & Structural Biology, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071019.134553.
Texto completoClinkinbeard, Tiffanie. "CHRONIC PANCREATITIS, PAIN, AND ANXIETY IN AN ALCOHOL AND HIGH FAT MOUSE MODEL". UKnowledge, 2016. http://uknowledge.uky.edu/gerontol_etds/9.
Texto completoBorrelli, Dina M. "Examining the relationship among measures of anxiety, self- confidence, arousal, and performance of elite field hockey players". Virtual Press, 1997. http://liblink.bsu.edu/uhtbin/catkey/1041905.
Texto completoSchool of Physical Education
Čulig, Luka. "Effets de l'augmentation de la neurogénèse adulte dans un modèle murin écologique de dépression". Thesis, Tours, 2017. http://www.theses.fr/2017TOUR4021.
Texto completoMajor depressive disorder (MDD) is a complex and heterogeneous disorder hypothesized to be associated with alterations in brain circuitry, dysregulations of the hypothalamic–pituitary–adrenal axis and impairments in adult hippocampal neurogenesis (AHN). Multiple lines of evidence point to the involvement of AHN in mood and anxiety disorders, leading to the formation of the “neurogenesis hypothesis”, which postulates that adult-born hippocampal neurons are involved in the etiology and treatment efficacy of MDD. The purpose of this study was to determine the role of adult-born neurons after the onset of stress exposure and the mechanism that underlies the observed results. Our results suggest that increasing neurogenesis is sufficient to buffer against the effects of chronic stress on certain behavioral and endocrine levels and thus to display antidepressant-like effects, both behaviorally and physiologically. Adult-born neurons might have exerted some of their effects via the anteromedial division of the bed nucleus of the stria terminalis (BSTMA)
Kempster, Cody C. y University of Lethbridge Faculty of Arts and Science. "Postural anxiety influences the allocation of attentional resources among younger and older adults". Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Kinesiology, 2010, 2010. http://hdl.handle.net/10133/2555.
Texto completoxi, 107 leaves : ill. ; 29 cm
Dupret, David. "Etude des relations réciproques entre neurogénèse adulte et fonctions hippocampiques". Bordeaux 2, 2007. http://www.theses.fr/2007BOR21431.
Texto completoThe dentate gyrus (DG) of the hippocampal formation (HF) is one of the few regions where an ongoing neurogenesis persists throughout adulthood. So far, the functional implication of hippocampal newborn neurons remains misunderstood. My work aimed to examine the reciprocical relationship adult neurogenesis and hippocampal functions. In particular I examined : 1) the causal relationship between adult neurogenesis and both the physiology and pathophysiology of hippocampal functions and, 2) whether hippocampo-dependent spatial learning influences the different steps of neurogenesis. First, we developed an original transgenic approach allowing specific ablation of adult hippocampal precursors cells. We found that depleted adult neurogenesis impairs spatial relational memory and increases anxiety-like responses. We discussed the putative implication of hippocampal newborn neurons in information processing. Second, we found that adult neurogenesis is regulated by spatial learning. Indeed, learning in the water maze modulates the fate of new neurones by selecting them for either survival or death depending on their level of integration when performances are stabilized. More precisely, apoptotic removal of young newborn neurones is required for both the survival of older ones and the stabilization of spatial performances. Such a learning-dependent regulation of adult neurogenesis is discussed in the context of selective stabilisation. Overall, my work shows that adult neurogenesis is a unique example of structural plasticity involved in both the physiology and pathophysiology of hippocampal functions
Giles, David. "Psychophysiological and emotional antecedents of climbing performance". Thesis, University of Derby, 2017. http://hdl.handle.net/10545/621900.
Texto completoWiczynski, Teresa. "Interactions between Aerobic Exercise Volume, Academic Stress, and Immune Function". TopSCHOLAR®, 2018. https://digitalcommons.wku.edu/theses/2334.
Texto completoKinsey, Steven G. "Behavioral and immunological effects of repeated social defeat". Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1171579586.
Texto completoPatin, Valentine. "Effets d'un stress prénatal appliqué à des rates gestantes sur leur comportement maternel et sur le développement, l'anxiété et l'apprentissage de leur progéniture". Rouen, 2001. http://www.theses.fr/2001ROUES036.
Texto completoSakkour, Sam. "Etude comparative et expérimentale de l'expression de la douleur chez les patients cancéreux français et syriens". Caen, 2012. http://www.theses.fr/2012CAEN1637.
Texto completoOwens, Maryann. "Does Virtual Reality Elicit Physiological Arousal in Social Anxiety Disorder". Master's thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5832.
Texto completoM.S.
Masters
Psychology
Sciences
Psychology Clinical
Ortolani, Daniela. "Efeitos de dieta palatável sobre a resposta de estresse em ratos". [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314637.
Texto completoDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Tem sido proposto que o acesso a alimentos palatáveis atenua a resposta de estresse. O objetivo deste estudo foi examinar o efeito de uma dieta palatável sobre parâmetros comportamentais e hormonais de ratos submetidos a estresse por choque nas patas. Ratos controles e estressados preferiram dieta palatável à comercial e a diminuição da ingestão alimentar induzida pelo estresse foi abolida em ratos com acesso a dieta palatável. Como conseqüência das diferenças de ingestão alimentar entre os grupos, ratos estressados e alimentados com dieta comercial consumiram quantidade inferior de calorias quando comparados com os controles, enquanto que ratos com acesso a dieta palatável ingeriram quantidade maior de calorias, não sendo alterado pelo estresse. Apesar dessas diferenças o peso corporal não se alterou. Ratos submetidos ao estresse aumentaram o número de entradas e o tempo de permanência no braço aberto do labirinto em cruz elevado (LCE), e também o número de imersões de cabeça. O número de estiramentos e de avaliações de risco foi diminuído pelo estresse por choque nas patas. A dieta palatável também diminuiu o número de avaliações de risco. Os animais submetidos ao estresse e com acesso ao alimento palatável apresentaram maior latência para o primeiro cruzamento e permaneceram mais tempo no centro do campo aberto. O número de levantamentos avaliado no campo aberto aumentou com a ingestão de dieta palatável, e o número de cruzamentos, auto-limpezas e bolos fecais não foi alterado pelo estresse nem pela composição da dieta. O aumento da concentração sérica de corticosterona induzido pelo estresse foi atenuado pela ingestão de dieta palatável. O estresse aumentou as concentrações de glicose e de insulina, e diminuiu as concentrações de triacilgliceróis. O consumo de dieta palatável aumentou a concentração de glicose, de leptina e de triacilgliceróis. Esses resultados mostram que o estresse reduz a ingestão alimentar e que esta redução é prevenida pelo acesso a dieta palatável. Este protocolo de estresse induziu à diminuição da ansiedade, com atenuação da concentração de corticosterona pelo alimento palatável. A combinação de dieta palatável e estresse afeta parâmetros metabólicos que podem levar à resistência a insulina. O efeito anorexigênico do estresse aconteceu independente da concentração de leptina, portanto outros fatores devem estar envolvidos com o controle do comportamento alimentar, como por exemplo, CRF e outros peptídeos, devendo ser estudados neste modelo experimental.
Abstract: It has been proposed that the access to palatable foods attenuates the stress response. The aim of this study was to examine the effect of a palatable diet on behavioral and hormonal parameters of rats submitted to footshock stress. Both control and stressed rats preferred the palatable than commercial diet and the stress-induced decrease in food intake was abolished in rats with access to palatable diet. As a consequence of the differences in food intake between the groups, rats submitted to stress and fed with commercial diet consumed a lower amount of calories than control rats, whereas rats with access to palatable diet ingested a higher amount of calories that was not altered by stress. Despite these differences, the body weight not altered. Rats submitted to stress increased the number of entries and the time spent in the open arms in the elevated plus maze (EPM), and also the number of head dipping. The number of stretched-attend posture and the risk assessment were decreased by footshock stress. The palatable diet also decrease the number of risk assessment. The rats submitted to stress with access to palatable diet showed a higher latency to the first crossing, and spent more time in the centre in the open field. The number of rearing increased with palatable diet intake, and the number of crossing, grooming and fecal bolus were not altered by stress neither diet composition. The stress-induced increase in serum corticosterone concentration was attenuated by palatable diet. The stress increased the serum glucose and insulin concentrations, and decreased the triacylglycerols concentrations. The access to palatable diet increased the glucose, leptin and triacylglycerols concentrations. These results showed that the stress reduces the intake food and that this reduction is prevented by access to palatable diet. This protocol of stress induced less anxiety-like behaviors with attenuation of corticosterone concentration induced by palatable diet. It is concluded that stress associated with palatable diet intake affect metabolic parameters that may lead to insulin resistance. Moreover, footshock stress had an anorexigenic effect that was independent of leptin, therefore other factors involved with the control of feeding behavior, such as CRF or other peptides, must be investigated in this experimental model.
Mestrado
Fisiologia
Mestre em Biologia Funcional e Molecular
Handouzi, Wahida. "Traitement d'information mono-source pour la validation objective d'un modèle d'anxiété : application au signal de pression sanguine volumique". Thesis, Université de Lorraine, 2014. http://www.theses.fr/2014LORR0237/document.
Texto completoDetection and evaluation of emotions are areas of great interest in many communities both in terms of human and exact sciences. In this thesis we focus on social anxiety recognition, which is an irrational fear felt by a person during any form of social relationship. Anxiety can be revealed by a set of physical and physiological traits such as tone of voice, facial expressions, increased heart rate, flushing ... etc. The interest to the physiological measures is motivated by them robustness to avoid the artifacts created by human social masking, they are a continuous source of data and each emotion is characterized by a particular physiological variation. In this work, we propose a measurement system based on the use of a single physiological signal "Blood volume pulse BVP". The use of a single sensor limits the subjects’ discomfort. From the BVP signal we selected three relevant features which best represents the close relationship between this signal and anxiety status. This features set is classified using support vector machine SVM. The work undertaken in the field of emotion recognition frequently use, for information support, unreliable data do not always correspond to the situations envisaged. This lack of reliability may be due to several parameters among them the subjectivity of the evaluation method used (self-evaluation questionnaire, subjects…etc.). We have developed an approach to objective assessment of data based on the dynamics of selected features. The used database was recorded in our laboratory under real conditions acquired in subjects with a level of anxiety during social situations and who are not under psychological treatment. The used stimulus is the exposition to virtual environments representing some feared social situations. After the evaluation stage, we obtained a reliable model for the recognition of two levels of anxiety. The latter was tested in a clinic specializing in cognitive behavioral therapy (CBT) on phobic subjects. The results highlight the reliability of the built model specifically for the recognition of anxiety levels in healthy subjects or of phobic subjects, what constitutes a solution to the lack of data affecting different areas of recognition
Dubar, Marie. "TREM-1 et parodontite : évaluation clinique de l’effet du traitement étiologique parodontal sur les concentrations de TREM-1 soluble et études in vitro de l’impact de P. gingivalis sur l’expression de TREM-1 par des cellules du parodonte". Thesis, Université de Lorraine, 2019. http://www.theses.fr/2019LORR0205.
Texto completoPeriodontal diseases are chronic multifactorial inflammatory diseases, affecting the tissues surrounding the teeth. The current consensus concerning their etiopathogenesis recognizes that the majority of tissue destruction is the result of a complex dysbiotic infectious process associated with immune system dysfunctions possibly exacerbated by general factors such as stress/anxiety. TREM-1 (Triggering Receptor Expressed on Myeloid cells-1) is an immunoreceptor expressed by neutrophils and monocytes/macrophages. It plays a fundamental role in the early stages of the inflammatory response and in particular in its amplification via TLRs (Toll-like receptor). In a clinical study in patients with periodontitis, we have observed, for the first time, the effects of a non-surgical periodontal treatment on the concentrations of the soluble receptor of TREM-1, sTREM-1, remaining higher in non-improved sites. However, TREM-1s, a potential marker of the inflammatory state of the site, does not appear to be a predictive marker of periodontal healing after treatment. Clinical results also provide a new insight into the complexity of the relationships between microbiological, clinical and psychosocial factors. At the same time, the use of the peptide LR12, modulator of TREM-1, induced decreased production of pro-inflammatory cytokines in in vitro models of monocytes stimulated by Porphyromonas gingivalis, a major periodontopathogen. This TREM-1 modulating agent could potentially be an interesting adjuvant in periodontal therapies to limit the amplitude of the inflammatory response without completely inhibiting it
Pantelidis, Dimitrios. "Analyse multiparamétrique des facteurs de la performance du joueur de tennis". Clermont-Ferrand 2, 1996. http://www.theses.fr/1996CLF22521.
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