Literatura académica sobre el tema "Aminoglycosides uptake"
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Artículos de revistas sobre el tema "Aminoglycosides uptake"
Ford, D. M., R. H. Dahl, C. A. Lamp y B. A. Molitoris. "Apically and basolaterally internalized aminoglycosides colocalize in LLC-PK1 lysosomes and alter cell function". American Journal of Physiology-Cell Physiology 266, n.º 1 (1 de enero de 1994): C52—C57. http://dx.doi.org/10.1152/ajpcell.1994.266.1.c52.
Texto completoRodriguez, Mônica B. y Sérgio O. P. Costa. "Spontaneous kanamycin-resistant Escherichia coli mutant with altered periplasmic oligopeptide permease protein (OppA) and impermeability to aminoglycosides". Revista de Microbiologia 30, n.º 2 (abril de 1999): 153–56. http://dx.doi.org/10.1590/s0001-37141999000200013.
Texto completoMcCollister, Bruce D., Matthew Hoffman, Maroof Husain y Andrés Vázquez-Torres. "Nitric Oxide Protects Bacteria from Aminoglycosides by Blocking the Energy-Dependent Phases of Drug Uptake". Antimicrobial Agents and Chemotherapy 55, n.º 5 (22 de febrero de 2011): 2189–96. http://dx.doi.org/10.1128/aac.01203-10.
Texto completoEzraty, Benjamin, Alexandra Vergnes, Manuel Banzhaf, Yohann Duverger, Allison Huguenot, Ana Rita Brochado, Shu-Yi Su et al. "Fe-S Cluster Biosynthesis Controls Uptake of Aminoglycosides in a ROS-Less Death Pathway". Science 340, n.º 6140 (27 de junio de 2013): 1583–87. http://dx.doi.org/10.1126/science.1238328.
Texto completoMao, Weimin, Mark S. Warren, Angela Lee, Anita Mistry y Olga Lomovskaya. "MexXY-OprM Efflux Pump Is Required for Antagonism of Aminoglycosides by Divalent Cations inPseudomonas aeruginosa". Antimicrobial Agents and Chemotherapy 45, n.º 7 (1 de julio de 2001): 2001–7. http://dx.doi.org/10.1128/aac.45.7.2001-2007.2001.
Texto completoKang, Hyung Sub, Dirk Kerstan, Long-jun Dai, Gordon Ritchie y Gary A. Quamme. "Aminoglycosides inhibit hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells". Canadian Journal of Physiology and Pharmacology 78, n.º 8 (1 de agosto de 2000): 595–602. http://dx.doi.org/10.1139/y00-038.
Texto completoJassem, Agatha N., James E. A. Zlosnik, Deborah A. Henry, Robert E. W. Hancock, Robert K. Ernst y David P. Speert. "In VitroSusceptibility of Burkholderia vietnamiensis to Aminoglycosides". Antimicrobial Agents and Chemotherapy 55, n.º 5 (14 de febrero de 2011): 2256–64. http://dx.doi.org/10.1128/aac.01434-10.
Texto completoHadidi, Kaivin, Ezequiel Wexselblatt, Jeffrey D. Esko y Yitzhak Tor. "Cellular uptake of modified aminoglycosides". Journal of Antibiotics 71, n.º 1 (1 de noviembre de 2017): 142–45. http://dx.doi.org/10.1038/ja.2017.131.
Texto completoJiang, Meiyan, Hongzhe Li, Anastasiya Johnson, Takatoshi Karasawa, Yuan Zhang, William B. Meier, Farshid Taghizadeh, Allan Kachelmeier y Peter S. Steyger. "Inflammation up-regulates cochlear expression of TRPV1 to potentiate drug-induced hearing loss". Science Advances 5, n.º 7 (julio de 2019): eaaw1836. http://dx.doi.org/10.1126/sciadv.aaw1836.
Texto completoSchlessinger, D. "Failure of aminoglycoside antibiotics to kill anaerobic, low-pH, and resistant cultures." Clinical Microbiology Reviews 1, n.º 1 (enero de 1988): 54–59. http://dx.doi.org/10.1128/cmr.1.1.54.
Texto completoTesis sobre el tema "Aminoglycosides uptake"
Subedi, Yagya P. "Cost-Effective Synthesis, Bioactivity and Cellular Uptake Study of Aminoglycosides with Antimicrobial and Connexin Hemichannel Inhibitory Activity". DigitalCommons@USU, 2019. https://digitalcommons.usu.edu/etd/7699.
Texto completoLang, Manon. "Un nouveau mécanisme d’entrée des aminosides dans les bactéries Gram-négative". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS143.
Texto completoThe number of deaths due to multidrug-resistant bacteria was over one million in 2019, demonstrating that the fight against pathogenic bacteria is a major public health issue. Aminoglycosides (AGs) are broad-spectrum antibiotics, effective against Gram-negative bacteria due to their ability to cross the double membrane barrier using the proton motive force, but the precise mechanism remains to be elucidated. Our laboratory has discovered a novel mechanism of entry of AGs into V. cholerae via sugar transporters. In this study, we showed that overexpression in Escherichia coli of multiple carbohydrate transporters increased sensitivity to AGs while deletion of a single transporter had little impact on sensitivity, suggesting a redundancy of these transporters capable of compensating for each other and limiting the development of resistance. Using a "proof-of-concept" transporter called CmtA, we confirmed that differential entry of AGs was linked to the deletion or overexpression of this transporter. This mechanism is shared with other pathogens, since the same sensitivity to AGs was observed upon overexpression of sugar transporters in Pseudomonas aeruginosa. Increasing the production of these transporters in response to the presence of a substrate in vivo could allow for greater efficacy and lower side effects of AG therapies by allowing better uptake by bacteria. We therefore sought a substrate capable of increasing the expression of transporters involved in AG uptake, and identified the ribonucleoside uridine as an activator. The addition of uridine to the culture medium allows for greater AG uptake in E. coli and did not show a mutant appearance. By mimicking a urinary tract infection with a synthetic medium, the addition of uridine potentiates AG treatment by decreasing the minimum inhibitory concentration of AGs and accelerating death kinetics. We propose uridine as a potentiator of GA treatment by co-administering an AG with uridine to stimulate its entry. This study paves the way for improving these treatments by using carbohydrates to stimulate AGs molecules uptake
Capítulos de libros sobre el tema "Aminoglycosides uptake"
Sidders, Ashelyn E., Lauren C. Radlinski, Sarah E. Rowe y Brian P. Conlon. "Stimulating Aminoglycoside Uptake to Kill Staphylococcus aureus Persisters". En Methods in Molecular Biology, 223–36. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1621-5_15.
Texto completoTulkens, Paul M. y Zoltan Kallay. "Uptake and Subcellular Distribution of Poly-L-Aspartic Acid, a Protectant Against Aminoglycoside-Induced Nephrotoxicity, in Rat Kidney Cortex". En Nephrotoxicity, 189–92. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-2040-2_27.
Texto completoBuchanan, Ruaridh y David Wareham. "Mechanisms of Antibiotic Resistance". En Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0055.
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