Literatura académica sobre el tema "ACTIVE TRAINING, AMBLYOPIA, VISUAL PLASTICITY"
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Artículos de revistas sobre el tema "ACTIVE TRAINING, AMBLYOPIA, VISUAL PLASTICITY"
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Halička, Juraj, Erik Sahatqija, Michal Krasňanský, Karolína Kapitánová, Monika Fedorová y Peter Žiak. "Visual Training in Virtual Reality in Adult Patients With Anisometric Amblyopia". Czech and Slovak Ophthalmology 76, n.º 1 (5 de diciembre de 2019): 24–28. http://dx.doi.org/10.31348/2020/3.
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Purpose: Amblyopia is one of the most common childhood disease. The average prevalence of amblyopia in children is estimated at 2-5 %. It arises during the child development until the age of six, if not treated then, it persist throught adulthood. The aim of our work is to retrospectively analyze the results of treatment of anisometropic amblyopia using dichoptical training in virtual reality in adult amblyopic patients. Materials and Methods: Our group consisted of 84 amblyopic patients with anisometropic amblyopia with an average age of 33.8 ± 9.4 years. Patients played a video game twice a week in the Oculus Rift 3D virtual reality. Together they completed 8 visual trainings, with one training lasting 60 minutes. Before and after the training we evaluated the best corrected visual acuity (BCVA). Discussion: Throughout the group, we observed an improvement of 0.1 BCVA from 0.48 to 0.58 Sloan table (p <0.05). 17% of patients before training and 31% after visual training reached BCVA better or equal to 0.9. The overall response rate was 56% in adult patients (n = 47). Conclusion: Our results suggest that a certain degree of residual neuro-plasticity in the visual cortex can be revealed in the adult brain, thereby improve visual acuity in adult amblyopic patients.
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Jeon, Seong Taek, Daphne Maurer y Terri L. Lewis. "The Effect of Video Game Training on the Vision of Adults with Bilateral Deprivation Amblyopia". Seeing and Perceiving 25, n.º 5 (7 de julio de 2012): 493–520. http://dx.doi.org/10.1163/18784763-00002391.
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Amblyopia is a condition involving reduced acuity caused by abnormal visual input during a critical period beginning shortly after birth. Amblyopia is typically considered to be irreversible during adulthood. Here we provide the first demonstration that video game training can improve at least some aspects of the vision of adults with bilateral deprivation amblyopia caused by a history of bilateral congenital cataracts. Specifically, after 40 h of training over one month with an action video game, most patients showed improvement in one or both eyes on a wide variety of tasks including acuity, spatial contrast sensitivity, and sensitivity to global motion. As well, there was evidence of improvement in at least some patients for temporal contrast sensitivity, single letter acuity, crowding, and feature spacing in faces, but not for useful field of view. The results indicate that, long after the end of the critical period for damage, there is enough residual plasticity in the adult visual system to effect improvements, even in cases of deep amblyopia caused by early bilateral deprivation.
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Sauvan, Lauren, Natacha Stolowy, Danièle Denis, Frédéric Matonti, Frédéric Chavane, Robert F. Hess y Alexandre Reynaud. "Contribution of Short-Time Occlusion of the Amblyopic Eye to a Passive Dichoptic Video Treatment for Amblyopia beyond the Critical Period". Neural Plasticity 2019 (28 de agosto de 2019): 1–12. http://dx.doi.org/10.1155/2019/6208414.
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Dichoptic movie viewing has been shown to significantly improve visual acuity in amblyopia in children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion in adults. In this study, we first asked whether dichoptic movie viewing could improve the visual function of amblyopic subjects beyond the critical period. Secondly, we tested if this effect could be enhanced by short-term monocular occlusion of the amblyopic eye. 17 subjects presenting stable functional amblyopia participated in this study. 10 subjects followed 6 sessions of 1.5 hour of dichoptic movie viewing (nonpatched group), and 7 subjects, prior to each of these sessions, had to wear an occluding patch over the amblyopic eye for two hours (patched group). Best-corrected visual acuity, monocular contrast sensitivity, interocular balance, and stereoacuity were measured before and after the training. For the nonpatched group, mean amblyopic eye visual acuity significantly improved from 0.54 to 0.46 logMAR (p<0.05). For the patched group, mean amblyopic eye visual acuity significantly improved from 0.62 to 0.43 logMAR (p<0.05). Stereoacuity improved significantly when the data of both groups were combined. No significant improvement was observed for the other visual functions tested. Our training procedure combines modern video technologies and recent fundamental findings in human plasticity: (i) long-term plasticity induced by dichoptic movie viewing and (ii) short-term adaptation induced by temporary monocular occlusion. This passive dichoptic movie training approach is shown to significantly improve visual acuity of subjects beyond the critical period. The addition of a short-term monocular occlusion to the dichoptic training shows promising trends but was not significant for the sample size used here. The passive movie approach combined with interocular contrast balancing even over such a short period as 2 weeks has potential as a clinical therapy to treat amblyopia in older children and adults.
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Hernández-Rodríguez, Carlos J., David P. Piñero, Ainhoa Molina-Martín, León Morales-Quezada, Dolores de Fez, Luis Leal-Vega, Juan F. Arenillas y María Begoña Coco-Martín. "Stimuli Characteristics and Psychophysical Requirements for Visual Training in Amblyopia: A Narrative Review". Journal of Clinical Medicine 9, n.º 12 (9 de diciembre de 2020): 3985. http://dx.doi.org/10.3390/jcm9123985.
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Active vision therapy using perceptual learning and/or dichoptic or binocular environments has shown its potential effectiveness in amblyopia, but some doubts remain about the type of stimuli and the mode and sequence of presentation that should be used. A search was performed in PubMed, obtaining 143 articles with information related to the stimuli used in amblyopia rehabilitation, as well as to the neural mechanisms implied in such therapeutic process. Visual deficits in amblyopia and their neural mechanisms associated are revised, including visual acuity loss, contrast sensitivity reduction and stereopsis impairment. Likewise, the most appropriate stimuli according to the literature that should be used for an efficient rehabilitation of the amblyopic eye are described in detail, including optotypes, Gabor’s patches, random-dot stimuli and Vernier’s stimuli. Finally, the properties of these stimuli that can be modified during the visual training are discussed, as well as the psychophysical method of their presentation and the type of environment used (perceptual learning, dichoptic stimulation or virtual reality). Vision therapy using all these revised concepts can be an effective option for treating amblyopia or accelerating the treatment period when combining with patching. It is essential to adapt the stimuli to the patient’s individual features in both monocular and binocular training.
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Gupta, Reena, Richa Jangra, Gaurav Dubey, Ramesh Hooda y Nirmal Parmar. "Efficacy of vision therapy in impaired stereoscopic depth with intermittent exotropia (true divergence excess) with unilateral amblyopia: a case report". International Journal Of Community Medicine And Public Health 7, n.º 2 (28 de enero de 2020): 773. http://dx.doi.org/10.18203/2394-6040.ijcmph20200466.
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Divergence excess (DE) can be described clinically as exotropia at far greater than the near deviation by at least 10 prism dioptres (PD). We are reporting a rare case of 25-year-old female visited in the eye department for a routine eye check-up with a history of decreased vision in one eye. On examination, it was detected as a case of unilateral amblyopia with intermittent exotropia of true divergence excess with high accommodative-convergence over accommodation (AC/A) ratio. The patient was asymptomatic from exo-deviation due to the presence of binocular vision and good fusional reserve. The patient was started on active conventional vision therapy along with occlusion therapy. Post 16 weeks of constant therapy, a vision assessment with complete squint assessment along with binocular vision tests were performed. The result interprets to support the use of active conventional vision therapy as an integral part of the clinical treatment of amblyopia and intermittent exotropia. The rate of recovery of several monocular functions monitored during the vision therapy period provides the evidence of neural plasticity at multiple sites in the visual pathway in this adult amblyope. Therefore, if an ordered plan is being followed for the management of the patient of unilateral amblyopia and divergence excess, it can yield long-lasting improvement in visual acuity and binocular functions of any age.
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Lagas, Alice K., Joanna M. Black, Bruce R. Russell, Robert R. Kydd y Benjamin Thompson. "The Effect of Combined Patching and Citalopram on Visual Acuity in Adults with Amblyopia: A Randomized, Crossover, Placebo-Controlled Trial". Neural Plasticity 2019 (9 de junio de 2019): 1–10. http://dx.doi.org/10.1155/2019/5857243.
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Nonhuman animal models have demonstrated that selective serotonin reuptake inhibitors (SSRIs) can enhance plasticity within the mature visual cortex and enable recovery from amblyopia. The aim of this study was to test the hypothesis that the SSRI citalopram combined with part-time patching of the fellow fixing eye would improve amblyopic eye visual acuity in adult humans. Following a crossover, randomized, double-blind, placebo-controlled design, participants completed two 2-week blocks of fellow fixing eye patching. One block combined patching with citalopram (20 mg/day) and the other with a placebo tablet. The blocks were separated by a 2-week washout period. The primary outcome was change in amblyopic eye visual acuity. Secondary outcomes included stereoacuity and electrophysiological measures of retinal and cortical function. Seven participants were randomized, fewer than our prespecified sample size of 20. There were no statistically significant differences in amblyopic eye visual acuity change between the active (mean±SD change=0.08±0.16 logMAR) and the placebo (mean change=−0.01±0.03 logMAR) blocks. No treatment effects were observed for any secondary outcomes. However, 3 of 7 participants experienced a 0.1 logMAR or greater improvement in amblyopic eye visual acuity in the active but not the placebo blocks. These results from a small sample suggest that larger-scale trials of SSRI treatment for adult amblyopia may be warranted. Considerations for future trials include drug dose, treatment duration, and recruitment challenges. This study was preregistered as a clinical trial (ACTRN12611000669998).
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Marsh, Eric y Robert Baker. "Normal and Adapted Visuooculomotor Reflexes in Goldfish". Journal of Neurophysiology 77, n.º 3 (1 de marzo de 1997): 1099–118. http://dx.doi.org/10.1152/jn.1997.77.3.1099.
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Marsh, Eric and Robert Baker. Normal and adapted visuooculomotor reflexes in goldfish. J. Neurophysiol. 77: 1099–1118. Under normal physiological conditions, whole field visual motion generally occurs in response to either active or passive self-motion. In the laboratory, selective movement of the visual surround produces an optokinetic response (OKR) that acts primarily to support the vestibuloocular reflex (VOR). During visual world motion, however, the OKR can be viewed as operating independently over frequency and amplitude ranges insufficient for vestibular activation. The goal of the present study was to characterize this isolated behavior of the OKR in goldfish as an essential step for studying central neuronal correlates of visual-vestibular interactions and the mechanisms underlying oculomotor adaptation. After presentation of either binocular sinusoidal or step visual stimuli, conjugate eye movements were elicited with an amplitude and phase profile similar to that of other vertebrates. An early and a delayed component were measured with different dynamics that could be altered independently by visual training. The ensuing visuomotor plasticity was robust and exhibited five major characteristics. First, the gain of both early and delayed components of the OKR increased >100%. Second, eye velocity decreased 0.5–2.0 s before the change in direction of stimulus velocity. Third, on lengthening the duration of a constant velocity visual stimulus (e.g., from 8 to 16 s), eye velocity decreased toward 0°/s. This behavior was correlated with the direction and period as opposed to the frequency of the visual stimulus (“period tuning”). Fourth, visual stimulus training increased VOR eye velocity with a ratio of 0.6 to 1 to that measured for the OKR. Fifth, after OKR adaptation, eye velocity consistently oscillated in a conjugate, symmetrical fashion at 2.4 Hz in the light, whereas in the dark, a rhythmical low-amplitude eye velocity occurred at the visual training frequency. We conclude that the frequency and amplitude of visual stimuli for eliciting the goldfish OKR are well suited for complementing the VOR. Unlike most mammals, OKR adaptive modifications significantly alter VOR gain, whereas the effects of VOR training are much less on OKR gain. These observations suggest that both distributed circuits and discrete neuronal populations control visuo- and vestibulomotor performance. Finally, the existence of a rhythmic, “period tuned” visuomotor behavior provides a unique opportunity to examine the neuronal mechanisms of adaptive plasticity.
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Cybulska-Klosowicz, Anita, François Tremblay, Wan Jiang, Stéphanie Bourgeon, El-Mehdi Meftah y C. Elaine Chapman. "Differential effects of the mode of touch, active and passive, on experience-driven plasticity in the S1 cutaneous digit representation of adult macaque monkeys". Journal of Neurophysiology 123, n.º 3 (1 de marzo de 2020): 1072–89. http://dx.doi.org/10.1152/jn.00014.2019.
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This study compared the receptive field (RF) properties and firing rates of neurons in the cutaneous hand representation of primary somatosensory cortex (areas 3b, 1, and 2) of 9 awake, adult macaques that were intensively trained in a texture discrimination task using active touch (fingertips scanned over the surfaces using a single voluntary movement), passive touch (surfaces displaced under the immobile fingertips), or both active and passive touch. Two control monkeys received passive exposure to the same textures in the context of a visual discrimination task. Training and recording extended over 1–2 yr per animal. All neurons had a cutaneous receptive field (RF) that included the tips of the stimulated digits (D3 and/or D4). In area 3b, RFs were largest in monkeys trained with active touch, smallest in those trained with passive touch, and intermediate in those trained with both; i.e., the mode of touch differentially modified the cortical representation of the stimulated fingers. The same trends were seen in areas 1 and 2, but the changes were not significant, possibly because a second experience-driven influence was seen in areas 1 and 2, but not in area 3b: smaller RFs with passive exposure to irrelevant tactile inputs compared with recordings from one naive hemisphere. We suggest that added feedback during active touch and higher cortical firing rates were responsible for the larger RFs with behavioral training; this influence was tempered by periods of more restricted sensory feedback during passive touch training in the active + passive monkeys. NEW & NOTEWORTHY We studied experience-dependent sensory cortical plasticity in relation to tactile discrimination of texture using active and/or passive touch. We showed that neuronal receptive fields in primary somatosensory cortex, especially area 3b, are largest in monkeys trained with active touch, smallest in those trained with passive touch, and intermediate in those trained using both modes of touch. Prolonged, irrelevant tactile input had the opposite influence in areas 1 and 2, favoring smaller receptive fields.
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Stefano Filho, Carlos Alberto, Romis Attux y Gabriela Castellano. "Motor imagery practice and feedback effects on functional connectivity". Journal of Neural Engineering 18, n.º 6 (1 de diciembre de 2021): 066048. http://dx.doi.org/10.1088/1741-2552/ac456d.
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Abstract Objective. The use of motor imagery (MI) in motor rehabilitation protocols has been increasingly investigated as a potential technique for enhancing traditional treatments, yielding better clinical outcomes. However, since MI performance can be challenging, practice is usually required. This demands appropriate training, actively engaging the MI-related brain areas, consequently enabling the user to properly benefit from it. The role of feedback is central for MI practice. Yet, assessing which underlying neural changes are feedback-specific or purely due to MI practice is still a challenging effort, mainly due to the difficulty in isolating their contributions. In this work, we aimed to assess functional connectivity (FC) changes following MI practice that are either extrinsic or specific to feedback. Approach. To achieve this, we investigated FC, using graph theory, in electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) data, during MI performance and at resting-state (rs), respectively. Thirty healthy subjects were divided into three groups, receiving no feedback (control), ‘false’ feedback (sham) or actual neurofeedback (active). Participants underwent 12–13 hands-MI EEG sessions and pre- and post-MI training fMRI exams. Main results. Following MI practice, control participants presented significant increases in degree and in eigenvector centrality for occipital nodes at rs-fMRI scans, whereas sham-feedback produced similar effects, but to a lesser extent. Therefore, MI practice, by itself, seems to stimulate visual information processing mechanisms that become apparent during basal brain activity. Additionally, only the active group displayed decreases in inter-subject FC patterns, both during MI performance and at rs-fMRI. Significance. Hence, actual neurofeedback impacted FC by disrupting common inter-subject patterns, suggesting that subject-specific neural plasticity mechanisms become important. Future studies should consider this when designing experimental NFBT protocols and analyses.
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Tyler, Sarah C., Federica Contò y Lorella Battelli. "Rapid Improvement on a Temporal Attention Task within a Single Session of High-frequency Transcranial Random Noise Stimulation". Journal of Cognitive Neuroscience 30, n.º 5 (mayo de 2018): 656–66. http://dx.doi.org/10.1162/jocn_a_01235.
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This study explored the modulatory effects of high-frequency transcranial random noise stimulation (tRNS) on visual sensitivity during a temporal attention task. We measured sensitivity to different onset asynchronies during a temporal order judgment task as a function of active stimulation relative to sham. While completing the task, participants were stimulated bilaterally for 20 min over either the TPJ or the human middle temporal area. We hypothesized that tRNS over the TPJ, which is critical to the temporal attention network, would selectively increase cortical excitability and induce cognitive training-like effects on performance, perhaps more so in the left visual field [Matthews, N., & Welch, L. Left visual field attentional advantage in judging simultaneity and temporal order. Journal of Vision, 15, 1–13, 2015; Romanska, A., Rezlescu, C., Susilo, T., Duchaine, B., & Banissy, M. J. High-frequency transcranial random noise stimulation enhances perception of facial identity. Cerebral Cortex, 25, 4334–4340, 2015]. In Experiment 1, we measured the performance of participants who judged the order of Gabors temporally imbedded in flickering discs, presented with onset asynchronies ranging from −75 msec (left disc first) to +75 msec (right disc first). In Experiment 2, we measured whether each participant's temporal sensitivity increased with stimulation by using temporal offsets that the participant initially perceived as simultaneous. We found that parietal cortex stimulation temporarily increased sensitivity on the temporal order judgment task, especially in the left visual field. Stimulation over human middle temporal area did not alter cortical excitability in a way that affected performance. The effects were cumulative across blocks of trials for tRNS over parietal cortex but dissipated when stimulation ended. We conclude that single-session tRNS can induce temporary improvements in behavioral sensitivity and that this shows promising insight into the relationship between cortical stimulation and neural plasticity.
Tesis sobre el tema "ACTIVE TRAINING, AMBLYOPIA, VISUAL PLASTICITY"
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berardi, nicoletta. "Active training promotes visual cortex plasticity and recovery from amblyopia in adult rats". Doctoral thesis, 2021. http://hdl.handle.net/2158/1260774.
Texto completoActas de conferencias sobre el tema "ACTIVE TRAINING, AMBLYOPIA, VISUAL PLASTICITY"
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Kim, Seung-Jae y Hermano Igo Krebs. "MIT-Skywalker: Preliminary Insights on Performance-Based Locomotor Training". En ASME 2010 Dynamic Systems and Control Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/dscc2010-4173.
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Gait rehabilitation promotes the reduction of gait deficits resulting from neurological pathologies by enhancing activity-dependent plasticity in the central nervous system. To maximize the therapeutic benefit of gait training, the key components appear to be subjects’ active participation and intensity. In this paper we discuss a performance-based training scheme for a novel gait trainer (MIT-Skywalker) that can challenge patients by systematically adjusting the treadmill speed and visual feedback. In our algorithm, the speed is adjusted based on gait performance of step length symmetry and subject’s ability to cope with the treadmill speed. Computer simulations demonstrate that the gait speed controller adapts to changes in walking performance, suggesting a potential scheme for gait therapy.