Artículos de revistas: "2003 i-838"

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Pich Mitjana, Josep y David Martínez Fiol. "Manuel Brabo Portillo. Policía, espía y pistolero (1876-1919)". Vínculos de Historia. Revista del Departamento de Historia de la Universidad de Castilla-La Mancha, n.º 8 (20 de junio de 2019): 387. http://dx.doi.org/10.18239/vdh_2019.08.20.

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RESUMEN:El objetivo del artículo es aproximarnos a la controvertida biografía del comisario Manuel Brabo Portillo. El trabajo está basado en fuentes primarias y secundarias. El método utilizado es empírico. En el imaginario del mundo sindicalista revolucionario, Brabo Portillo era el policía más odiado, la reencarnación de la cara más turbia del Estado. Fue, así mismo, un espía alemán relacionado con el hundimiento de barcos españoles, el asesinato del empresario e ingeniero Barret y el primer jefe de los terroristas vinculados a la patronal barcelonesa. La conflictividad que afectó a España en el período de la Primera Guerra Mundial es fundamental para entender los orígenes del terrorismo vinculado al pistolerismo, que marcó la historia político social española del primer tercio del siglo XX.PALABRAS CLAVE: Brabo Portillo, pistolerismo, espionaje, sindicalismo, Primera Guerra Mundial.ABSTRACT:The objective of the article is an approach to the controversial biography of Police Chief Manuel Brabo Portillo. The work is based on primary and secondary sources. The method used is empirical. In the imagery of the revolutionary syndicalist world, Brabo Portillo was the most hated policeman, the reincarnation of the murkiest face of the state. He was also a German spy connected with the sinking of Spanish ships, the murder of businessman and engineer Josep Barret and the first head of the terrorists linked to Barcelona employers. The conflict that affected Spain during the period of the First World War is fundamental in order to understand the origins of terrorism linked to pistolerismo, which marked Spanish social political history during the first third of the twentieth century.KEY WORDS: Brabo Portillo, pistolerismo, espionage, syndicalism, First World War. BIBLIOGRAFÍAAisa, M., La efervescencia social de los años 20. Barcelona 1917-1923, Barcelona, Descontrol, 2016.Aguirre de Cárcer, N., La neutralidad de España durante la Primera Guerra Mundial (1914-1918). I. Bélgica, Madrid, Ministerio de Asuntos Exteriores, 1995.Alonso, G., “’Afectos caprichosos’: Tradicionalismo y germanofilia en España durante la Gran Guerra”, Hispania Nova, 15, 2017, pp. 394-415.Amador, A., El Terror blanco en Barcelona. Las bombas y los atentados personales. Actuación infernal de una banda de asesinos al servicio de la burguesía. El asesinato como una industria, Tarragona, Talleres gráf. Gutenberg, [1920?].Anglés, C., “Contra los sindicatos. Los procesos de la organización obrera. La impostura nunca ha sido justicia”, Solidaridad Obrera, 836 (1/8/1918), p. 1.Balcells, A., El Pistolerisme. Barcelona (1917-1923), Barcelona, Pòrtic, 2009.Ben-Ami, S., La Dictadura de Primo de Rivera (1923-1930), Barcelona, Planeta, 1984.Bengoechea, S., Organització patronal i conflictivitat social a Catalunya. Tradició i corporativisme entre finals de segle i la dictadura de Primo de Rivera, Barcelona, PAM, 1994.Bengoechea, S., El locaut de Barcelona (1919-1920), Barcelona, Curial, 1998.Bengoechea, S., “1919: La Barcelona colpista. L’aliança de patrons i militars contra el sistema liberal”, Afers, 23/24 (1996), pp. 309-327.Brabo Portillo, M., Ensayo sobre policía científica, Barcelona, Gassó Hermanos, [190?].Bravo Portillo, M. y Samper, A., Programa para los exámenes de ingreso ó ascenso en plazas de oficiales de cuarta clase de la Hacienda Pública, Madrid, Mateu, 1906.Bueso, A., Recuerdos de un cenetista, Barcelona, Ariel, 1976.Burgos y Mazo, M. de, El verano de 1919 en Gobernación, Imprenta de E. Pinós-Cuenca, 1921.Calderón, F. de P. [Rico Ariza, E.] y Romero, I., Memorias de un terrorista. Novela episódica de la tragedia barcelonesa, Barcelona, [s.e.], [1924?].Carden, R. M., German Policy Toward Neutral Spain, 1914-1918, London, Routledge, 2014.Cardona, G., Los Milans del Bosch, una familia de armas tomar. Entre la revolución liberal y el franquismo, Barcelona, Edhasa, 2005.Casal Gómez, M., La Banda Negra. El origen y la actuación de los pistoleros en Barcelona (1918-1921), 2ª. Edición, Barcelona, Icaria, 1977.Calle Velasco, M. D. de la, “Sobre los orígenes del estado social en España”, Ayer, 25 (1997), pp. 127-150.D’Ors, E., “La unidad de Europa”, La Vanguardia, (1/12/1914), p. 7.Díaz Plaja, F., Francófilos y germanófilos. Los españoles en la guerra europea, Barcelona, Dopesa, 1973.Díez, P., Memorias de un anarcosindicalista de acción, Barcelona, Bellaterra, 2006.Domingo Méndez, R., “La Gran Guerra y la neutralidad española: entre la tradición historiográfica y las nuevas líneas de investigación”, Spagna Contemporanea, 34 (2008), pp. 27-44.Esculies, J., “España y la Gran Guerra. Nuevas aportaciones historiográficas”, Historia y Política, 32 (2014), pp. 47-70.Esdaile, Ch. J., La Quiebra del liberalismo, 1808-1939, Barcelona, Crítica, 2001.Foix, P., Los Archivos del terrorismo blanco. El fichero Lasarte (1910-1930), Madrid, Las Ediciones de la Piqueta, 1978.Forcadell, C., Parlamentarismo y bolchevización. El movimiento obrero español, 1914-1918, Barcelona, Crítica, 1978.Fuentes Codera, M., “El somni del retorn a l’Imperi: Eugeni d’Ors davant la Gran Guerra”, Recerques, 55 (2007), pp. 73-93.Fuentes Codera, M., “Germanófilos y neutralistas. Proyectos tradicionalistas y regeneracionistas para España (1914-1918)”, Ayer, 91/3 (2013), pp. 63-92.Fuentes Codera, M., España en la Primera Guerra Mundial. Una movilización cultural, Madrid, Akal, 2014.García Oliver, J., El Eco de los pasos, Paris/Barcelona, Ruedo Ibérico, 1978.García Sanz, F., España en la Gran Guerra, Madrid, Galaxia Gutenberg, 2014.Giráldez, E., “Brabo Portillo ¡Yo te acuso, Asesino!”, Solidaridad Obrera, 840 (5/8/1918), p. 1.Golden, L., “Les dones com avantguarda; El rebombori del pa del gener 1918”, L’Avenç (1981), pp. 45-52.Golden, L., “The women in command. The Barcelona women’s consumer war of 1918”, UCLA Historical Journal (1985), pp. 5-32.E. González Calleja y F. del Rey Reguillo, La Defensa armada contra la revolución. Una historia de las guardias cívicas en la España del siglo XX, Madrid, CSIC, 1995.González Calleja, E., La Razón de la fuerza. Orden público, subversión y violencia política en la España de la Restauración, 1875-1917, Madrid, CSIC, 1998.González Calleja, E., El Máuser y el sufragio. Orden público, subversión y violencia política en la crisis de la Restauración (1917-1931), Madrid, CSIC, 1999.González Calleja, E., (ed.), Políticas del miedo. Un balance del terrorismo en Europa, Madrid, Biblioteca Nueva, 2002.González Calleja, E., La España de Primo de Rivera. La modernización autoritaria 1923-1930, Madrid, Alianza Editorial, 2005.González Calleja, E., El laboratorio del miedo. Una historia general del terrorismo, Barcelona, Crítica, 2013.González Calleja, E. y Aubert, P., Nidos de espías. España, Francia y la Primera Guerra Mundial, Madrid, Alianza, 2014.González Calleja, E. (coord.), Anatomía de una crisis. 1917 y los españoles, Madrid, Alianza, 2017.Granados de Siles, J., “El escandaloso espionaje de Barcelona”, Solidaridad Obrera, 793 (19/6/1918), p. 1.Gual Villalbí, P., Memorias de un industrial de nuestro tiempo, Barcelona, Sociedad General de Publicaciones, [193?].León-Ignacio, J., Los años del pistolerismo. Ensayo para una guerra civil, Barcelona, Planeta, 1981.León-Ignacio, J., “Brabo Portillo, comisario y político”, Historia y vida, 181 (1983), pp. 68-73.Llates, R., 30 anys de vida catalana, Barcelona, Aedos, 1969.Madrid, F., Ocho meses y un día en el Gobierno Civil de Barcelona (confesiones y testimonios), Barcelona-Madrid, Las ediciones de la flecha, 1932.Manent, J., Records d’un sindicalista llibertari català, 1916-1943, París, Edicions Catalanes de París, 1976.Marquès, J., Història de l’organització sindical tèxtil “El Radium”, Barcelona, La Llar del Llibre, 1989.Márquez, B. y Capo, J. M., Las Juntas militares de defensa, Barcelona, Librería Sintes, 1923.Martínez Fiol, D., El catalanisme i la Gran Guerra (1914-1918). Antologia, Barcelona, La Magrana, 1988.Martínez Fiol, D. y Esculies Serrat, J., L’Assemblea de Parlamentaris de 1917 i la Catalunya rebel, Barcelona, Generalitat de Catalunya, 2017.Martínez Fiol, D. y Esculies Serrat, J., 1917. El año en que España pudo cambiar, Sevilla, Renacimiento, 2018.M.C.C., “El ‘affaire’ Brabo Portillo”, publicado en El Parlamentario y reproducido por Solidaridad Obrera, 926 (2/11/1918), p. 1.Mendoza, E., La verdad sobre el caso Savolta, Barcelona, Seix y Barral, 1975.Morales Lezcano, V., El colonialismo hispano-francés en Marruecos (1898-1927), Madrid, Siglo XXI, 1976.Navarra, A., 1914. Aliadófilos y germanófilos en la cultura española, Madrid, Cátedra, 2014.Navarra, A., Aliadòfils i germanòfils a Catalunya durant la Primera Guerra Mundial, Barcelona, Generalitat-CHCC, 2016.Nisk, “¡Inocente Brabo!”, Solidaridad Obrera, 789 (15/6/1918), p, 1.Pestaña, Á.,“A vuela pluma” y “En Libertad”, Solidaridad Obrera, 840-841 (5-6/8/1918), p. 1.Pestaña, Á., Terrorismo en Barcelona. Memorias inéditas, Barcelona, Planeta, [1979].Pradas Baena, M. A., L’anarquisme i les lluites socials a Barcelona 1918-1923. La repressió obrera i la violència, Barcelona, PAM, 2003.Pujadas, X., Marcel·lí Domingo i el marcel·linisme, [Barcelona], PAM, 1996.Roig, M., Rafael Vidiella. L’aventura de la revolució, Barcelona, Laia, 1976.Romero Salvadó, F. J., “Crisi, agonia i fi de la monarquía liberal (1914-1923)”, Segle XX. Revista catalana d’història, 1 (2008), pp. 57-82.Romero Salvadó, F. J. y Smith, A. (eds.), The Agony of Spanish Liberalism. FromRevolution to Dictatorship 1913-23, Houndmills, Basingstoke, Palgrave Macmillan, 2010.Rosenbusch, A., “Los servicios de información alemanes: sabotaje y actividad secreta”, Andalucía en la historia, 45 (2014), pp. 24-29.Rosenbusch, A., “Guerra Total en territorio neutral: Actividades alemanas en España durante la Primera Guerra Mundial”, Hispania Nova, 15 (2017), pp. 350-372.S. A., “Historia de un ‘bravo’ muy pillo”, La Campana de Gracia, 2569 (28/6/1918), p. 4.S.A., L’Esquella de la Torratxa, (12/7 y 30/8/ y 12/9/1918), pp. 447, 451, 456, 458, 568, 577 y 592.S. A., “A cada puerco le llega su San Martín” y “La muerte de Batet”, Solidaridad Obrera, 711 y 712 (9 y 10/1/1918), p. 1.S. A., Solidaridad Obrera, 713-716 (11-14/1/1918), p. 1.S. A., “Los conflictos del hambre”, Solidaridad Obrera, 717, 719-721 y 723-727 (15 y 17-19 y 21-25/1/1918), p. 1.S.A., Solidaridad Obrera, 783 y 784-786, (9-12/6/1918), p. 1.S.A., Solidaridad Obrera, 789-790, 794-795, 798 (15-16, 20-21 y 24/6/1918), p. 1.S. A., Solidaridad Obrera, 833 y 837 (28/7 y 2/8/1918), p. 1.S. A., Solidaridad Obrera, (3/7 y 12/12/1918), p. 2.S.A., “Veredicto popular”, Solidaridad Obrera, 790, 791, 793, 794, 795, 798, 799, 800, 802, 808, 809, 810, 811, 815, 816, 817, 818, 819, 820, 821, 822, 823, 825, 826, 827, 828, 829, 830, 832, 833, 834, 835, 836, 837, 838, 839 (16, 17, 19, 20, 21, 24, 25, 26, 28/6; 4, 5, 6, 7, 11, 12, 13, 14, 15, 16, 17, 18, 19, 21, 22, 23, 24, 25, 26, 28, 29, 30, 31/7; 1, 2, 3, 4/8/1918), pp. 1-3.S.A., “Envío a doña Remedios Montero de Brabo Portillo”, 871 (7/9/1918), p. 1.S.A., Solidaridad Obrera, (24, 25, 26, 27, 28 y 30/6 y 3, 6, 8, 5, 10, 12, 13 y 19/7, 4, 5, 9, 23, 24 y 26/8, 21, 24, 25, 31/10, 1, 2/11/ y 1-6, 8, 10, 11, 12, 14, 15, 20, 30 y 31/12/1918), pp. 1-4.Safont, J., Per França i Anglaterra. La I Guerra Mundial dels aliadòfils catalans, Barcelona, Acontravent, 2012.Sánchez Marín, A. L., “El Instituto de Reformas Sociales: origen, evolución y funcionamiento”, Revista Crítica de Historia de las Relaciones Laborales y de la Política Social, 8 (mayo 2014), pp. 7-28.Smith, A., “The Catalan Counter-revolutionary Coalition and the Primo de Rivera Coup, 1917–23”, European History Quaterly 37:1 (2007), pp. 7-34.Smith, A., Anarchism, revolution and reaction. Catalan labor and the crisis of the Spanish State, 1898-1923, New York, Oxford, Berghahn, 2007.Soldevilla, F., El Año político 1920, Madrid, I. de Julio Cosano, 1921.Taibo II, P. I., Que sean fuego las estrellas. Barcelona (1917-1923), Barcelona, Crítica, 2016.Tamames, R. y Casals, X., Miguel Primo de Rivera, Barcelona, Ediciones B, 2004.Tusell, J., Radiografía de un golpe de estado. El ascenso al poder del general Primo de Rivera, Madrid, Alianza, 1987.Val, R. del y Río del Val, J. del, Solidaridad Obrera, 787-788, 790, 794, 801, 805, 807, 811, 814, 818, 828, 829, 836, 970 (13, 14, 16, 20 y 27/6/, 3, 7, 10, 14, 23, 24 y 31/7/ y 1/8/ y 10/121918), p. 1.Vandellós, P., “Contra los sindicatos. Los procesos de la sindicación obrera. De actualidad”, Solidaridad Obrera, 791 (17/6/1918), p. 1.Vidiella, R., Los de ayer. Novela, Madrid-Barcelona, Nuestro Pueblo, 1938.Winston, C. M., La Clase trabajadora y la derecha en España (1900-1936), Madrid, Cátedra, 1989.Winston, C. M., “Carlist workers groups in Catalonia, 1900-1923”, en S. G. Payne (dir.), Identidad y nacionalismo en la España contemporánea: el carlismo, 1833-1975, Madrid, Actas, 1996, pp. 85-101.Wosky, Solidaridad Obrera, 791, 801 y 820, (17 y 21/6/ 10/7/1918), pp. 1 y 3.

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Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang y Haicheng Ma. "Connected even factors in k-tree". Open Mathematics 18, n.º 1 (29 de diciembre de 2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract A connected even {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i(i=2,4,\ldots ,2s) , where s\ge 1 is an integer. In this paper, we show that a \tfrac{k+1}{s+2} -tough k-tree has a connected even {[}2,2s] -factor and thereby generalize the result that a \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].

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Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang y Haicheng Ma. "Connected even factors in k-tree". Open Mathematics 18, n.º 1 (1 de enero de 2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract A connected even [ 2 , 2 s ] {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i ( i = 2 , 4 , … , 2 s ) i(i=2,4,\ldots ,2s) , where s ≥ 1 s\ge 1 is an integer. In this paper, we show that a k + 1 s + 2 \tfrac{k+1}{s+2} -tough k-tree has a connected even [ 2 , 2 s ] {[}2,2s] -factor and thereby generalize the result that a k + 1 3 \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].

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Stock, Wendy, Ben Sanford, Gerard Lozanski, Ravi Vij, John C. Byrd, Bayard L. Powell, Meir Wetzler et al. "Alemtuzumab can be Incorporated Into Front-Line Therapy of Adult Acute Lymphoblastic Leukemia (ALL): Final Phase I Results of a Cancer and Leukemia Group B Study (CALGB 10102)." Blood 114, n.º 22 (20 de noviembre de 2009): 838. http://dx.doi.org/10.1182/blood.v114.22.838.838.

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Abstract Abstract 838 Eradication of minimal residual disease (MRD) during the first months of ALL treatment is associated with improved disease-free survival (DFS). We hypothesized that alemtuzumab, a humanized anti-CD52 monoclonal antibody, might be an effective, novel agent for eradication of MRD. In CALGB 10102, we tested dose escalation of alemtuzumab in sequential cohorts of CD52+ cases to a target dose of 30 mg administered SC 3 times/week for 4 weeks (12 doses) during post-remission therapy. Dose limiting toxicity (DLT) was defined as the inability to proceed with protocol treatment within 6 weeks after the last dose of alemtuzumab. Eligible patients (pts) had ≥10% lymphoblast CD52 expression at diagnosis determined in a CALGB reference laboratory. Antimicrobial prophylaxis for cytomegalovirus (CMV) and Pneumocystis carinii was mandated. The 10102 therapy consisted of 6 monthly chemotherapy modules followed by maintenance therapy for a total of 2 years (Stock et al. ASH 2005, abstr 145); 299 untreated ALL pts were eligible and enrolled from 2003–2007. We previously reported (Lozanski et al. ASH 2007, abstr 2386) that 70% were CD52+ and eligible to receive Alemtuzumab (70% of B-cell ALL; 53% of T-cell ALL; 100% of Ph+ cases). Results: Twenty-four pts in remission (CR1) received Alemtuzumab as their fourth treatment module during the Phase I portion of the study. The median age was 37 years (18-77 years); 18 (80%) had B-cell ALL; 5 (19%) had T-cell ALL. 17/24 cases had evaluable cytogenetics after central review: 5 had favorable, 8 intermediate-risk, 2 poor-risk cytogenetics (neither were Ph+), and 2 were not classifiable (miscellaneous abnormalities). Non-hematologic toxicities were mild. SC alemtuzumab was well tolerated. Grade 3-4 myelosuppression was reported during 4 weeks of alemtuzumab treatment in 4 pts; 2 pts had Grade 3-4 lymphopenia. 4 pts had DLT: subsequent treatment was delayed in 2 due to transient CMV viremia; 1 developed Staph aureus empyema; and 1 had prolonged myelosuppression but did not receive G-CSF support as recommended by the protocol. 3 pts relapsed with ALL immediately following completion of the alemtuzumab module. Serial assessment of MRD using quantitative clone-specific PCR was possible in 11/24 cases. There was a median 1-log decrease in MRD during alemtuzumab therapy in the 20 and 30 mg cohorts. However, there was a 2-log rise during alemtuzumab therapy in one pt who relapsed 6 weeks later. Pharmacokinetic analysis revealed rising alemtuzumab serum levels during treatment in all dose cohorts, and levels were still detectable in some pts 10 weeks after completing alemtuzumab. During subsequent post-remission therapy, 8 pts developed CMV viremia, 2 had Herpes simplex infections, and 3 had Herpes zoster reactivation. There was not a significant correlation between serum alemtuzumab level and change in MRD or risk of viral infection. The median follow-up time for the 14 surviving pts is 51 months (49-54 months). Median DFS is 53 months (95% CI, 39 – not reached); median overall survival is 55 months (95% CI, 42- not reached). Conclusions: CD52 is expressed in the majority of adult ALL cases. Addition of alemtuzumab to front-line therapy is feasible and provides reduction in MRD, but is associated with viral infections. Dose escalation of alemtuzmab was not associated with DLT. Based on these results, the 30 mg dose of alemtuzumab was explored in an additional 70 patients in the Phase II portion of the study. The encouraging DFS results reported here require confirmation from longer follow-up of the larger Phase II cohort of patients. Disclosures: Stock: Genzyme: Research Funding. Off Label Use: The testing of alemtuzumab for treatment of ALL in adults. Lozanski:Genzyme: Research Funding. Vij:CELGENE: Honoraria, Research Funding, Speakers Bureau. Powell:Antisoma: Research Funding. Sher:invivoscribe: Employment. Richards:Genzyme: Employment. Sung:genzyme: Employment.

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Kushner, James P., Michael R. Franklin, Christopher P. Reilly, Hector A. Bergonia y John D. Phillips. "An Inhibitor of Uroporphyrinogen Decarboxylase (URO-D) Causes Porphyria Cutanea Tarda (PCT)." Blood 108, n.º 11 (16 de noviembre de 2006): 270. http://dx.doi.org/10.1182/blood.v108.11.270.270.

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Abstract Hepatic iron content is increased in patients with PCT and phlebotomy-induced iron depletion corrects the clinical and biochemical phenotype. Approximately 20 percent of patients with PCT are homozygous for mutations of the hemochromatosis gene (HFE) but the cause of iron overload in most patients is unknown. Hepatic URO-D activity is markedly reduced when PCT is manifest and URO-D activity improves following iron depletion. Most patients with PCT have no mutations of the URO-D gene (sporadic PCT) but approximately 1/3 of cases are heterozygous for URO-D mutations (familial PCT) (BLOOD. 2000; 95:1565–71). To determine the mechanism by which iron overload causes PCT we created 3 murine models: Mice with one null allele of Uro-d (Uro-d+/−) and 2 null Hfe alleles (Hfe−/ −) (PNAS.2001; 98:259–64); Uro-d+/− mice treated with iron-dextran, aminolevulinic acid (ALA) and polychlorinated biphenyls (PCB) and; wild type mice treated with iron, ALA and PCB (J. Biochem. Mol. Toxicol.2001; 15:287–93). All models accumulate uroporphyrin in the liver and all have hepatic URO-D activity of 25% or less but Western blots revealed no change in URO-D protein. An iron deficient diet prevented the PCT phenotype in Uro-d+/−, Hfe−/ − animals and greatly attenuated the phenotype in animals treated with ALA and PCB (Env. Toxicol. Pharmacol.2005; 417–23). Liver homogenates from all porphyric models were heat denatured and clarified by centrifugation. The supernatants inhibited the activity of purified recombinant human URO-D (rhURO-D) by approximately 60%. The inhibitory activity was further purified by solid phase extraction and HPLC. The fraction containing the inhibitory activity did not fluoresce. Mass spectrometry of this fraction demonstrated a dominant peak with a mass of 835 Da and an absorption maximum of approximately 500 nM, the optical signature of a porphomethene. An inhibitor with identical properties was generated by partially oxidizing the uroporphyrinogen (837 Da) substrate of URO-D under UV light. Full oxidation of either the inhibitor purified from porphyric mouse liver or from partially oxidized, enzymatically generated uroporphyrinogen (either isomer I or III) yielded a compound with a mass of 831 Da and an absorption maximum of approximately 400 nM, indicating that the fully oxidized inhibitor was uroporphyrin. Tandem mass spectrometry of the 835 Da inhibitor indicated that the inhibitor was a tetrapyrrole. Collectively these data indicate that the inhibitor is a porphomethene derived form uroporphyrinogen through oxidation of a single bridge carbon between adjacent pyrrole rings. An inhibitor of rhURO-D was also identified in heat-denatured cytosol from liver biopsy samples obtained from four humans with PCT. We conclude that clinical expression of PCT requires an iron dependant oxidation reaction that generates a porphomethene inhibitor of URO-D.

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De Los Ríos, José F., Juan D. Castañeda, Gustavo A. Calle, Eduardo Serna, Ricardo A. Vásquez, Adriana M. Arango, Orlando J. Flórez, Ana M. Mejía, Victoria Arango y Tatiana Palacio. "Histerectomía laparoscópica total en la unidad de endoscopia ginecológica de la Clínica del prado, Medellín (Colombia) 2002 - 2008". Revista Colombiana de Obstetricia y Ginecología 60, n.º 4 (20 de diciembre de 2009): 320–27. http://dx.doi.org/10.18597/rcog.314.

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Objetivo: describir la experiencia en la práctica de Histerectomía Laparoscópica Total (HLT) con énfasis en las complicaciones presentadas.Metodología: el presente es un estudio de cohorte histórica en el cual se incluyeron las pacientes que fueron intervenidas entre diciembre de 2002 y abril de 2008 y en quienes, además, se completó al menos 90% de la información requerida en un formulario prediseñado. Durante la investigación, se evaluaron las características sociodemográficas, las indicaciones de cirugía, el porcentaje de laparoconversión y las causas de la misma, el tiempo quirúrgico, la pérdida sanguínea estimada, el tiempo de hospitalización, el número de dosis de analgésicos requeridos, los días de incapacidad y las complicaciones intraoperatorias y postoperatorias.Resultados: en total se incluyeron 837 pacientes, cuya edad promedio fue 42,7 años. 83,8% de las mujeres eran ASA I (American Society of Anesthesiologists) y la principal enfermedad de base fue la hipertensión arterial (9,9%). En 822 de ellas, el procedimiento se llevó a cabo por laparoscopia mientras que 15 (1,7%) requirieron laparoconversión. Las indicaciones más frecuentes para la cirugía fueron miomatosis (43,8%) y hemorragia uterina anormal (36,1%). Adicional a esto, el tiempo quirúrgico promedio fue 85,9 minutos, la pérdida sanguínea media fue de 60,6 mL y la tasa total decomplicaciones llegó a ser 12,5%; de lacuales,3,1% lo constituyeron complicaciones mayores.Conclusiones: la tasa de complicaciones de la histerectomía laparoscópica total es similar a la informada en la literatura y está acompañada de una estancia hospitalaria breve.

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Marinkovic, Smiljana, Svetlana Bukarica, Mihajlo Jeckovic, Svetlana Skoric, Jelena Antic y Zvezdana Starcevic. "Ultrasound-guided water enema for reduction of childhood intussusception". Medical review 60, n.º 11-12 (2007): 605–9. http://dx.doi.org/10.2298/mpns0712605m.

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Introduction. Intussusception is a common abdominal emergency in infants and children. Ultrasonography and barium enema are very useful in diagnosis and treatment of this condition. The aim of the study was to assess the accuracy of ultrasound-guided saline enema for intussusception and to determine if some factors may improve the outcome of this technique. Material and methods. Intussusception was diagnosed in 63 patients at the Clinic of Pediatric Surgery in Novi Sad. The study period was divided into two 2-year phases: phase I, from 2001 through 2002, and phase II, from 2003 through 2004. During phase I, besides barium enema and fluoroscopy, we started using ultrasonography and ultrasound-guided hydrostatic saline enema in the diagnosis and reduction of intussusception. In phase II, this method of reduction was routinely used in all cases. Our technique of ultrasonic reduction was similar to the conventional hydrostatic barium reduction, except the reservoir was higher than that of barium, analgosedation ot patients was performed and in case of difficult and prolonged reduction, gentle manual pressure to the abdomen at right lower quadrant was used. Results. In phase I the diagnostic accuracy of ultrasonography in detecting intussusception was 53.8% , and 100% in phase II. The success rate of ultrasound-guided saline enema was 55.5% in phase I, and 83.8% in phase II. Only 6 patients (16.2%) underwent operative manual reduction of intussusception in phase II. There were no cases with bowel gangrene or perforations in both groups. Conclusions. Ultrasonography is a useful screening tool in the diagnosis of intussusception. The main advantage of hydrostatic reduction with ultrasound guidance is avoidance of ionizing radiation. The success rate of this method of reduction may be increased with an integrated team approach to the management and with modifications of the technique.

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Vergote, Ignace B., Florence Joly, Dionyssios Katsaros, Corneel Coens, Alexander Reinthaller, Marcia Hall, Christopher B. Steer et al. "Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma: A GCIG and EORTC-GCG study." Journal of Clinical Oncology 30, n.º 18_suppl (20 de junio de 2012): LBA5000. http://dx.doi.org/10.1200/jco.2012.30.18_suppl.lba5000.

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LBA5000 Background: The epidermal growth factor receptor (EGFR) has been found to be overexpressed in 55-98% of advanced epithelial ovarian cancer. This trial evaluated the efficacy of maintenance erlotinib, an EGFR tyrosine kinase inhibitor, after first-line chemotherapy. Methods: Eligible patients (pts) had high-risk FIGO stage I or stage II-IV epithelial ovarian, peritoneal or fallopian tube cancer and were not selected for EGFR expression. All patients underwent first line therapy (6-9 cycles of 3-weekly platinum-based chemotherapy (CT)) and showed no signs of progression at the end of CT. Patients were randomised to maintenance erlotinib 150 mg daily for 2 years or observation. Primary endpoint was progression-free survival (PFS) by RECIST in combination with GCIG CA125 criteria. The final design provided 80% power to detect a PFS hazard ratio (HR) of 0.80 with 2-sided log-rank test at 5% after 632 events in 830 patients. Stratifications factors were stage, institution, age, response to and type of first-line CT. Immunohistochemistry (IHC) and FISH for EGFR, and EGFR mutation analyses were performed in 330 patients. The study was registered as NCT00263822 and EudraCT number 2004-004333-34. Results: Between Oct 2005 and Feb 2008, 835 pts were randomised by 125 institutions from 10 countries. The most important baseline characteristics, PFS and OS are summarized in the table. Median follow-up was 51 months. 25% of the patients stopped erlotinib due to side effects (of these 67% due to rash). The predictive value of IHC and FISH for EGFR, and EGFR mutations are being evaluated and will be presented at the meeting. Conclusions: In the overall study populationmaintenance erlotinib after first-line treatment in ovarian cancer did not improve progression-free or overall survival. [Table: see text]

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Peelen, E., A. Muehler, D. Vitt y H. Kohlhof. "P064 IMU-838, a Small Molecule DHODH Inhibitor in Phase 2 Clinical Trial for Ulcerative Colitis, Shows Potent Anti-inflammatory Activity in Cell-Culture-Based and In Vivo Systems". Journal of Crohn's and Colitis 16, Supplement_1 (1 de enero de 2022): i172—i173. http://dx.doi.org/10.1093/ecco-jcc/jjab232.193.

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Abstract Background IMU-838 (vidofludimus calcium) is a well-tolerated and orally available small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) and is currently in phase 2 clinical development for ulcerative colitis (UC). Here, we investigated the effect of IMU-838 on different immune cell subsets and analysed the mechanism of action in more detail in T cells. Methods The effect of IMU-838 on regulatory macrophages (Mregs) was investigated by adding IMU-838 or anti-TNFα antibodies (infliximab, adalimumab), alone or in combination, in a mixed lymphocyte reaction assay, determining Mregs (CD206+CD14+) by FACS analysis. To investigate the effect of IMU-838 on human T and B cells, PBMC were stimulated with PHA (48h) or Oligonucleotide 2006-PTO (70h), respectively. An affinity-dependent effect of IMU-838 was assessed on CD8 T cells from OT-I and OT-III mice, containing a high and a low affinity T cell receptor (TCR), respectively, for OVA257-264 peptide. These cells were stimulated with ovalbumin (OVA) peptide loaded splenocytes or anti-CD3/anti-CD28 for 3 days. Oxidative phosphorylation (OXPHOS) and glycolysis in murine T cells was investigated by the Seahorse/Agilent technique in murine CD4 and CD8 T cells activated with anti-CD3/anti-CD28 with or without IMU-838. Results IMU-838 slightly induced Mregs, but strongly and dose-dependently decreased TNFα and IL-6 secretion. Anti-TNFα antibodies alone strongly induced Mregs, but also increased IL-6 levels. When IMU-838 was added, Mregs induction was even higher, and IL-6 was reduced. Besides reducing proinflammatory cytokines secreted by macrophages, IMU-838 also inhibits proliferation of activated B and T cells, as well as inflammatory T cell cytokine secretion, IL-17A, IL-17F and IFNγ, and increased apoptosis up to 3-fold compared to vehicle control. By investigating IMU-838’s role on affinity related activity status of T cells, it was shown that IMU-838 strongly inhibited cell proliferation in the peptide stimulated high affinity, but not in the low affinity, CD8 T cells. Peptide stimulated high affinity T cells show an upregulation of OXPHOS and glycolysis pathways, which are involved in the generation of the cell’s energy supply, compared to low affinity cells. IMU-838 strongly inhibited OXPHOS and glycolysis in both CD4 and CD8 T cells. Conclusion IMU-838 reduces the proinflammatory immune cell response by inducing Mregs, reducing pro-inflammatory cytokine secretion and reducing immune cell proliferation. DHODH is only important in cells that received a strong stimulus and are highly metabolically active. Therefore, IMU-838 will only specifically target these cells and will still allow for a normal immune response, representing a huge safety advantage for treatment of IBD patients.

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Olivier, C. Y., G. Séguin-Swartz, D. Hegedus y T. Barasubiye. "First Report of “Candidatus Phytoplasma asteris”-Related Strains in Brassica rapa in Saskatchewan, Canada". Plant Disease 90, n.º 6 (junio de 2006): 832. http://dx.doi.org/10.1094/pd-90-0832c.

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“Candidatus phytoplasma asteris” and related strains (i.e., aster yellows group 16SrI) have been associated with diseases of numerous plant species worldwide. Symptoms of aster yellows (AY) have been reported on rapeseed/canola (Brassica napus and B. rapa) crops in Saskatchewan (SK) and Manitoba, Canada since 1953 (2). Symptoms generally include stunting, virescence, leaf yellowing or purpling, phyllody, and formation of bladder-like siliques. A total of 120 mature B. rapa cv. AC Sunbeam plants exhibiting AY symptoms were collected in commercial fields near Medstead, SK during 2003 and 2004 (one field per year). As described previously (4), total genomic DNA was extracted from leaf, stem, roots, and seeds collected from the 120 plants, from seeds from the seed lots sown in 2003 and 2004, and from leaf and stem tissue of 20 greenhouse-grown plants from each seed lot. The latter DNA samples were assayed for phytoplasma DNA by a nested polymerase chain reaction (PCR) assay incorporating phytoplasma universal 16S rRNA primer pairs P1/P6 (1) followed by R16R2/R16F2 (4). Seed samples analyzed from the 2003 and 2004 seed lots and tissues of the 40 greenhouse-grown plants all tested negative for phytoplasma DNA using this assay. Leaf, stem, and/or root tissues of all plants collected in the field in 2003 (60 plants) and 2004 (60 plants) and 71.1% (315 of 443) of seed samples (five seeds per sample) tested positive for the presence of phytoplasma DNA, as evidenced by the presence of an expected band of 1.2 kb on the gels after the second amplification with primers R16R2/R16F2. Nested PCR products from plant samples collected in 2003 were cloned, sequenced, and compared with phytoplasma sequences archived in the GenBank nucleotide database. On this basis, phytoplasmas detected in plants or their seeds collected in 2003 were found to be most similar (98.8%) to CHRY (Accession No. AY180956), a 16SrI-A subgroup strain, or were most similar (98.9%) to isolate 99UW89 (Accession no. AF268407), a known 16SrI-B subgroup strain. Sequences of phytoplasmas detected in plants or their seeds in 2004 were obtained by direct sequencing of rRNA products amplified from samples using PCR incorporating primer pairs P1/P6 and P4/P7 (3). Analysis of sequence data revealed that phytoplasmas in these plants were all most similar (99.5%) to AY-WB (Accession no. AY389828), a 16SrI-A subgroup member. The nucleotide sequences have been deposited with GenBank under Accession nos. DQ404346, DQ404347, and DQ411470. To our knowledge, this is the first report of 16SrI-A and 16SrI-B subgroup phytoplasmas infecting plants and seed of B. rapa in Saskatchewan. References: (1) I.-M. Lee et al. Phytopathology, 83:834, 1993. (2) W. E. Sackston. Can. Plant Dis. Surv. 33:41, 1953. (3) L. B. Sharmila et al. J. Plant Biochem. Biotech. 13:1, 2004. (4) E. Tanne et al. Phytopathology, 91:741, 2001.

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CLARK, GEOFFREY. "COMMERCE, CULTURE, AND THE RISE OF ENGLISH POWER". Historical Journal 49, n.º 4 (24 de noviembre de 2006): 1239–51. http://dx.doi.org/10.1017/s0018246x06005814.

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Barclays: the business of banking, 1690–1996. By Margaret Ackrill and Leslie Hannah. Cambridge: Cambridge University Press, 2001. Pp. xxi+481. ISBN 0-521-79035-2. £45.00.The worlds of the East India Company. Edited by H. V. Bowen, Margarette Lincoln, and Nigel Rigby. Woodbridge: Boydell, 2002. Pp. xvii+246. ISBN 0-85115-877-3. £45.00.Kingship and crown finance under James VI and I, 1603–1625. By John Cramsie. Woodbridge: Boydell, 2002. Pp. xi+242. ISBN 0-86193-259-5. £50.00.Mammon's music: literature and economics in the age of Milton. By Blair Hoxby. New Haven: Yale University Press, 2002. Pp. xii+320. ISBN 0-300-09378-0. $45.00.Usury, interest, and the Reformation. By Eric Kerridge. Aldershot: Ashgate, 2002. Pp. 206. ISBN 0-7546-0688-0. £55.00.The rise of commercial empires: England and the Netherlands in the age of mercantilism, 1650–1770. By David Ormrod. Cambridge: Cambridge University Press, 2003. Pp. xvii+400. ISBN 0-521-81926-1. £55.00.The rhetoric of credit: merchants in early modern writing. By Ceri Sullivan. London: Associated University Presses, 2002. Pp. 217. ISBN 0-8386-3926-7. £38.00.The unshackling of the European economy from the sixteenth to the eighteenth centuries was achieved, ironically, by the forging of new and stronger chains of trade and credit within nations, across regions, and around the globe. The seven books under review explore that process from different disciplinary standpoints, but chiefly as it affected England, the country that would become emblematic of commercial advancement and under whose sway the modern capitalist system emerged. How England managed this feat financially and commercially, politically and culturally, amidst the shifting opportunities and perils of these centuries is answered with an often impressive sophistication and imagination that take us well beyond hackneyed analyses prompted by the Weber–Tawney thesis.

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Rzaguliyev, Vidadi A., Oruj S. Kerimli, Dilbar S. Ajdarova, Sharafat H. Mammadov y Ozbek M. Aliev. "Фазовые равновесия в системах Ag8SnS6–Cu2SnS3 и Ag2SnS3–Cu2Sn4S9". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, n.º 4 (19 de diciembre de 2019): 544–51. http://dx.doi.org/10.17308/kcmf.2019.21/2365.

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Комплексными методами физико-химического анализа (дифференциально-термический, рентгенофазовый, микроструктурный, измерение микротвердости и определение плотности) изучены фазовые равновесия и построены Т–х фазовые диаграммыв системах Ag8SnS6–Cu2SnS3 и Ag2SnS3–Cu2Sn4S9. Показано, что система Ag8SnS6–Cu2SnS3является квазибинарным сечением квазитройной системы Ag2S-SnS2-Cu2S и относится кпростому эвтектическому типу с ограниченными областями растворимости на основеисходных сульфидов. Координаты эвтектической точки: 50 mol % Ag2SnS3 И Т = 900 К.Растворимость на основе Ag8SnS6 и Cu2SnS3 при эвтектической температуре простираетсядо 20 и 28 mol % соответственно. С уменьшением температуры твердые растворы распадаются и при 300 К составляют 5 и 10 mol %. Установлено, что с увеличением концентрацииAg8SnS6 в твердых растворах (Cu2SnS3)1-х (Ag8SnS6)х параметр кубической решетки увеличивается от а = 0.5445 nm (для чистого Cu2SnS3) до а = 0.725 nm (для состава х = 0.1) т. е. концентрационная зависимость параметра решетки имеет линейный характер.Система Ag2SnS3–Cu2Sn4S9 из-за перитектического плавления Cu2Sn4S9 имеет сложный характер и является частично квазибинарным сечением. Квазибинарность нарушается вобласти концентрации 65-100 mol % Cu2Sn4S9 и выше температуры 900 К. Твердые растворына основе Ag2SnS3 и Cu2Sn4S9 узкие и при 300 К составляют 10; 2.5 mol % соответственно ЛИТЕРАТУРА1. Wang N., Fan A. K. An experimental study of the Ag2S-SnS2 pseudobinary join // Neues Jahrb. Mineral.-Abh, 1989, v. 160, pp. 33–36.2. Wang N. New data for Ag8SnS6 (canfeildite) and Ag8GeS6 (argyrodite) // Neues Jahrb. Mineral. Monatsh.,1978, pp. 269–272.3. Бабанлы М. Б., Юсибов Ю. А., Абишев В. Т. Трехкомпонентные халькогениды на основе медии серебра. Баку: Изд-во БГУ, 1993, 342 с.4. Parasyuk O. V., Chykhrij S. I., Bozhko V. V., Piskach L. V., Bogdanyuk M. S., Olekseyuk I. D.,Bulatetska L. V., Pekhnyo. Phase diagramm of the Ag2S–HgS–SnS2 system and single crystal prepartion,crystal structure and properties of Ag2HgSnS4 // J. Alloys and Compounds, 2005, v. 399, pp. 32–37. DOI: https://doi.org/10.1016/j.jallcom.2005.03.0085. Olekseyuk I. D., Dudchak I. B., Piskach L. V. Phase equilibria in the Cu2S–ZnSe–SnS2 // J. Alloys andCompounds, 2004, v. 368, pp. 135–143. https:doi.org/10.1016/j.jallcom.2003.08.0846. Ollitrault-Fitchet R., Rivet J., Flahaut J., et.al. Description du systeme ternaire Ag–Sn–Se // J. Less-Common. Met., 1988, v. 138(2), pp. 241–261. DOI:https://doi.org/10.1016/0022-5088(88)90113-07. Delgado C. E., Mora A. J., Marcano E. Crystal structure refi nement of the semiconducting compoundCu2SnSe3 from X-ray powder difraction data // Mater. Res. Bull., 2003, v. 38, pp. 1949–1955. DOI: https://doi.org/10.1016/j.materresbull.2003.09.0178. Parasyuk O. V., Olekseyuk I. D., Marchuk O. V. The Cu2Se–HgSe–SnSe2 // J. Alloys and Compounds.,1999, v. 287, pp. 197–205. DOI: https//doi.org/10.1016/S0925-8388(99)00047-X9. Parasyuk O. V., Gulay L. D., Piskach L. V., Kumanska Yu. O. The Ag2Se–HgSe–SnSe2 system and thecrystal structure of the Ag2HgSnSe4 // J. Alloys and Сompounds, 2002, v. 339, pp.1 40–143. DOI: https//doi.org/10.1016/S0925-8388(01)01985-510. Babanly M. B., Yusibov Y. A., Babanly N. B. Electromotive force and measucement in several systema.Ed. by S. Kara, Intechneb. Org., 2011, pp. 57–58.11. Gulay L. D., Olekseyuk I. D., Parasyuk O. V. Crystal structure of b-Ag8SnSe6 // J. Alloys and compounds,2002, v. 339, pp. 113–117. DOI: https//doi.org/10.1016/S0925-8388(01)01970-312. Гусейнов Г. М. Получение соединения Ag8SnS6 в среде диметилформамида // Вестн. Томского гос. ун-та. Химия, 2016, № 1(3), c. 24–34. Режим доступа: fi le:///C:/Users/Lab351/Downloads/sub_%20%20in%20dimethylformamide%20medium.pdf (дата обращения: 19.09.2019)13. Gorchov O. Les composes Ag8MX6 (M = Si, Ge, Sn et X = S, Se, Te) // Bull. Soc. Chim. Fr., 1968, № 6.pp. 2263–2275.14. Kokhan O. P. The Interactions in Ag2X–BIVX2 (BIV – Si, Ge, Sn; X – S, Se) systems and the propertiesof compounds. Doctoral Thesis, Uzhgorod, Uzhgorod State Univ., 1996.15. Onoda U., Chen X. A., Sato A., Wada H. Crystal structure and twinning of monoclinic Cu2SnS3 // Mater.Res. Bull., 2000, v. 35, № 8, pp. 1563–1570. DOI: https//doi.org/10.1016/S0025-5408(00)00347-016. Рзагулиев В. А., Керимли О. Ш., Мамедов Ш. Г. Изучение квазитройной системы Ag2S–SnS2–Cu2S по разрезу Ag8SnS6–Cu2SnS3. Труды Международ. научно–практич. конф., Россия, Белгород,2019, c. 18.17. Рзагулиев В. А., Керимли О. Ш., Маме дов Ш. Г. Исследование квазибинарного разреза Cu2SnS3–Ag2SnS3 в квазитройной системеAg2S–Cu2S–SnS2 . Труды XXI Междун. конф., Санкт-Петербург, 2019,c. 20–21.18. Цигика В. В., Переш Е. Ю., Лазарев В. В. и др. Получение и свойства мнонокристаллов соединений/TlPbJ3, Tl3PbJ5, TlSnJ3, TlSn2J5 and Tl3PbBr5 Изв. АН СССР. Неорган. материалы, 1981, т. 17(6), c. 970–974.

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Szabó, Éva. "Examination of the effects of the cropyear and the nutrient supply on the quality of winter wheat with the help of Győri’s Z-index". Acta Agraria Debreceniensis, n.º I (5 de octubre de 2010): 121–25. http://dx.doi.org/10.34101/actaagrar/i/8389.

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In the case of winter wheat,the knowledge of several quality features is needed to be able to determine precisely the real quality of the givenwheat. Several systems have been worked out on the qualification of the winter wheat in Hungary and other countries as well. Evaluating thequality is being made more difficult because the different quality features take part in the development of the quality in different degrees andthe values of the several quality features are in different intervals and these data are different dimension values. On the evidence of theresults, in the case of considering several features,it can be difficult to rank into one concrete quality cathegory. Researchers are trying todevelop complex quality index numbers in order to be able to define the quality more precisely. One of these complex quality index numbersis Gyıri’s, so called, Z-index.In three years from 2006 and 2008, we examined the change of the quality features of nine varieties of winter wheat with the help of theZ-index under the influence of the effects of the different cropyears and the fertilizer treatment. The results show that the Z-index of theexamined varieties of winter wheat were influenced by several factors. Examining the data of the three different breeding years together wecan observe the corrective effect of the different cropyears on the Z-index, and if we examine the three years separately and together, thedifferences of the quality features of the different varieties differentiate very well, and with the help of the Z-index the comparison of thetypes is easier and perspicuous, and the Z-index represents the different nutrient reactions of the different types as well. On the average ofthe three years, the types gave the best results at N120-150+PK nutrient level. Among the nine varieties the best results were given by Mv Suba,GK Békés and Mv Mazurka in the case of both low and higher nutrient levels.

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Hadi, Syamsul. "Lasem: Harmoni dan Kontestasi Masyarakat Bineka". ISLAM NUSANTARA: Journal for Study of Islamic History and Culture 1, n.º 1 (30 de julio de 2020): 163–208. http://dx.doi.org/10.47776/islamnusantara.v1i1.49.

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This article aims to explain how the contestation of social spaces in the lives of the plural society at Lasem it processes dynamically. It is a pattern of space contestation that leads to the affirmation and strengthening of identity or a pattern that leads to the fusion of identities. As a consequence, the first pattern creates social friction or conflict. On the contrary, the second pattern is directed towards acculturation and assimilation of culture which can strengthen social harmony. The important finding of this research is that it can be known the real issue, so that problems related to all parties can be found a solution as well as a resolution. This research also proves that social mechanism preparedness is considered urgent to prevent negative excesses (negative things) from the space contestation. So the space contestation that occurs dynamically proves that the plural society in Lasem has found a valuable experience, namely social resilience in facing all possible emergence of social disintegration.Keywords: contestation, space, social mechanisms and an plural society REFERENCE: Abercrombie, Nicholas, at.all., 2010. Kamus Sosiologi, Terj. Dwi Agus M. Yogyakarta: Pustaka Pelajar. Adhyanggono, GM. ad.all., 2009. Budaya Tionghoa Lasem Dalam Peta Tata Pemukiman, Tradisi, Peran Dan Relasi Gender, dalam Angelina Ika Rahutami (Peny.), ”Kekuatan Lokal Sebagai Roh Pembangunan Jawa Tengah”, Semarang: UNIKA Soegijapranata. Amirudin, 2017. Multikulturalisme dalam Produksi Budaya Seni Batik di Lasem, dalam; ”60 Tahun Antropologi Indonesia; Refleksi Kontribusi Antropologi untuk Indonesia”, Jakarta; Pusat Kajian Antropologi, Departemen Antropologi FISIP UI, 2017. Atabik, Ahmad, 2016. Percampuran Budaya Jawa dan Cina: Harmoni dan Toleransi Beragama Masyarakat Lasem, Jurnal: Sabda, Volume 11, Tahun 2016, pp. 1–11. Azra, Azyumardi, 2011. Nasionalisme, Etnisitas, Dan Agama di Indonesia: Perspektif Islam Dan Ketahanan Budaya, dalam Thung Ju Lan dan M. Azzam Manan (Ed.), ”Nasionalisme Dan Ketahanan Budaya di Indonesia”, Jakarta: LIPI & Yayasan Obor Indonesia. BPS. 2012. Data Monografi Kecamatan Lasem Semester II Tahun 2012, Rembang: Pemkab. Rembang. BPS. 2017. Data UPT Pendidikan Kabupaten Rembang Tahun 2017, Rembang: Pemkab. Rembang. BPS Rembang, 2017. Lasem Dalam Angka Tahun 2017, Rembang: Pemkab. Rembang. BPS Rembang, 2018. Lasem Dalam Angka Tahun 2018, Rembang: Pemkab. Rembang. Daradjati, 2013. Geger Pacinan 1740–1743: Persekutuan Tionghoa – Jawa Melawan VOC, Jakarta: Kompas. Hardiman, F. Budi, 2002 “Belajar dari Politik Multikulturalisme”, pengantar Will Kymlicka, ”Kewargaan Kultural”, Jakarta: LP3ES, 2002. Hartono, Samuel & Handinoto, Lasem: Kota Kuno Di Pantai Utara Jawa Yang Bernuasa Cina, artikel dalam: http://fportfolio. petra.ac.id/user_files/81-005/LASEM.pdf, diunduh pada tanggal 02 Agustus 2018, pukul: 14.23 wib. Hefner, Robert, W., 2001, The Politics of Multiculturalism: Pluralism and Citizenship in Malaysia, Singapore and Indonesia, Honolulu: University of Hawai Press. Jary, David & Jary, Yulia, 1991. Collins Dictionary of Sociology, London: Harper Collins Publishers. Khamzah, R.P. 1858. Cerita (Sejarah) Lasem, Katurun/Kajiplak Dening R. Panji Karsono (1920), dalam buku Badra Santi, Rumpakanipun Mpu Santribadra Nurhajarini, Dwi Ratna, ad.all. 2015. Akulturasi Lintas Zaman di Lasem: Perspektif Sejarah dan Budaya (Kurun Niaga – Sekarang), Yogyakarta: BPNB-Yogyakarta. Onghokham, Anti Cina, Kapitalisme Cina dan Gerakan Cina, Jakarta: Komunitas Bambu, 2008. Parekh, Bhikhu, 2012. Rethingking Multiculturalism: Keberagaman Budaya dan Teori Politik, diterjemahkan dari “Rethingking Multiculturalism, Cuktural Diversity dan Political Theory”, Yogyakarta: Kanisius. Pemkab. Rembang, 2012. Monografi Kecamatan Lasem Tahun 2012. Poloma, Margaret M. 2010. Sosiologi Konterporer, Jakarta: Rajawali Press. Purdey, Jemma, 2013. Kekerasan Anti Tionghoa Di Indonesia 1996–1999, Denpasar: Pustaka Larasan. Putra. Ade Yustirandy dan Sartini, 2016. Batik Lasem Sebagai Simbul Akulturasi Nilai-nilai Budaya Jawa-Cina, dalam; Jurnal Jantra Vol. 11, No. 2, Desember 2016. Ritzer, George & Goodman, Douglas J., 2011. Teori Sosiologi Modern, Jakarta: Prenada Media. Saifullah, Ahmad 2008. Makna Spiritual Arsitektur Masjid, paparan makalah SITI Angkatan Ke-4, dipresentasikan pada Kamis, 17 Juli 2008, Tidak Diterbitkan. Slattery, Martin, 2003. Key Ideas in Sociology, Delta Place Cheltenham: Nelson Thomas Ltd. Soekanto, Soejono. 1985. Karifan Masyarakat Dalam Penegolaan Kseserasian Sosial Ditinjau Dari Segi Hukum, dalam Majalah Bulanan Tahun VII, edisi No. 11/Agustus 1985, pp. 824-830. Suaedy, Ahmad, 2018. Gus Dur, Islam Nusantara, dan Kewarganegaraan Bineka: Penyelesaian Konflik Aceh dan Papua 1999–2001, Jakarta: Gramedia Pustaka Utama. Suryadinata, Leo, 2003. Kebijakan Negara Indonesia terhadap Etnik Tionghoa: Dari Asimilasi ke Multikulturalisme”, Jurnal Antropologi Indonesia, Nomor: 71, Tahun 2003. Suryadinata, Leo, 2010. Akhirya Diakui Agama Konghucu dan Agama Budha di Pasca-Suharto, dalam, ”Setelah Air Mata Kering” (Ed. I. Wibowo & Thung Ju Lan), Jakarta: Gramedia. Slattery, Martin, 2003. Key Ideas in Sociology, Delta Place Cheltenham: Nelson Thomas Ltd. Tan, Charlene, 2014. Educative Tradition and Islamic Schools in Indonesia, Nanyang Technological University, Singapore. Journal of Arabic and Islamic Studies-14 (2014). Tilaar, H.A.R. 2007. Mengindonesia: Etnisitas dan Identitas Bangsa Indonesia, Jakarta: Rineka Cipta. Tim Peneliti, ”Laporan Survei Nasional”: Kerjasama Wahid Foundation dengan Lembaga Survei Indonesia dan UN Women, Januari 2018. Turner, Jonathan H. dan Alexandra Maryanski, 2010. Fungsionalisme, Yogyakarta: Pustaka Pelajar. Unjiya, M. Akrom, 2008. “Lasem Negeri Dampo Awang: Sejarah Yang Terlupakan“, Yogyakarta: Fokmas, Veeger, K.J., 1985. Realitas Sosial: Refleksi Filsafat Sosial Atas Hubungan Individu-Masyarakat Dalam Cakrawala Sejarah Sosiologi, Jakarta: Gramedia. Wallace, Ruth A. dan Wolf, Alison, 2006. Contemporary Sociological Theory: Expanding The Classical Tradition, -6th ed., Pearson Education, Inc., Upper Saddle River, New Jersey. Wiroutomo, Paulus, 2012. Integrasi Sosial Masyarakat Indonesia: Teori dan Konsep, dalam Paulus Wiroutomo, ad.all., ”Sistem Sosial Indonesia”, Jakarta: UI Press & Lab-Sosio. Sumber Internet Surat Kabar Harian “Kompas”, edisi; 15 Pebruari 2014. Surat Kabar Harian “Suara Merdeka”, edisi: 23 Oktober 2019. "Said Aqil Singgung Sentimen Agama dan 212 di Depan Anies", sumber; https://www.cnnindo nesia.com/nasional/20191022212949-20-441966/said-aqil-sing gung-sentimen-agama-dan-212-di-depan-anies, diunduh pada tanggal 23 Oktober 2019. Pukul:07.43 wib.

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McArthur, Heather L., Karen A. Gelmon, Ivo A. Olivotto, Caroline H. Speers, Susan L. Ellard, Susan E. O'Reilly y Hagen F. Kennecke. "Effectiveness of a Letter Notification Program for Women With Early-Stage Breast Cancer Eligible for Extended Adjuvant Letrozole". Journal of Clinical Oncology 27, n.º 9 (20 de marzo de 2009): 1388–93. http://dx.doi.org/10.1200/jco.2008.18.4127.

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Purpose After National Cancer Institute of Canada trial MA.17 demonstrated benefits with letrozole after 5 years of tamoxifen, oncologists needed to identify and offer therapy to patients in community follow-up who were eligible for extended adjuvant hormone therapy. In British Columbia (BC), letters about extended letrozole therapy were sent to eligible BC women, their primary care physicians (PCPs), and their oncologists. We evaluated the effectiveness of this communication strategy. Patients and Methods Eight hundred eighty-five women with stage I-III breast cancer who completed 4 to 6 years of tamoxifen in 2004 with no documented recurrence were sent letters describing extended adjuvant letrozole in February 2005. Treatment uptake and characteristics for women who did or did not receive a subsequent letrozole prescription were described. Results Among 838 eligible women, 305 (36%) received a letrozole prescription before April 2006. More women in the letrozole cohort had tumors larger than 2.0 cm (44.2% v 30.8%); node-positive disease (52.5% v 22.5%); prior radiotherapy (71.1% v 58.5%); and prior chemotherapy (51.5% v 20.8%; all P ≤ .001). Among women younger than 70 years with node-positive disease, 65% received letrozole (122 of 188). Most prescribing physicians were oncologists (57.0%) or PCPs (30.8%). A significant increase in letrozole prescriptions was observed after the letter mail-out. Conclusion In this population-based setting, extended adjuvant letrozole was more common among younger women with higher risk disease and more prior therapy but underutilized overall. The reasons for extended therapy underutilization and the role of the letter mail-out strategy in informing breast cancer survivors of new available treatments in other health systems warrant further study.

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Wittreck, Fabian y Stephan Wagner. "Der Amtshaftungsanspruch nach Art. 34 S. 1 GG/§ 839 I 1 BGB". JURA - Juristische Ausbildung 35, n.º 12 (15 de noviembre de 2013): 1213–25. http://dx.doi.org/10.1515/jura-2013-0153.

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Chairilsyah, Daviq. "Web-Based Application to Measure Motoric Development of Early Childhood". JPUD - Jurnal Pendidikan Usia Dini 13, n.º 1 (30 de abril de 2019): 1–14. http://dx.doi.org/10.21009/10.21009/jpud.131.01.

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ABSTRACT Parents and early childhood educators still find it difficult to find ways to self-identify children's motor development, there needs to be innovation that measures motoric development can be easily used by parents The purpose of this study is to identify indicators of motor development in early childhood, make measuring instruments, and create a web-based measurement application. This Research and Development methodology uses mix method data analysis. This research is located in Indonesia with a sample of 590 participants. The results of the study show that valid and reliable measurement instruments for motoric development from the results of testing as many as 97 indicators are considered high value. Applications made by Information Technology experts to produce a systematic performance measurement system, making it easier for users, teachers / parents who are famous to get the results of the examination quickly and accurately. The implications of research are expected to be able to build a measuring device with the application of technology that is more developed in aspects of child development in addition to motor development, to become a facility for assessing early childhood development that makes it easier for educators to use it. Keywords: Early Childhood, Motoric Development, Web Based Application Instrument. REFERENCES Ali, A. (2012). Persepsi guru terhadap penggunaan kurikulum berasaskan bermain bagi aspek perkembangan bahasa dan literasi murid prasekolah. Malay Language Education Journal (MyLEJ), 2(1). Retrieved from https://www.researchgate.net/publication/327953978 Azwar, S. (2014). Reliabilitas dan Validitas Edisi 4. yogyakarta: Pustaka Pelajar. Barnett, L. M., Stodden, D., Miller, A. D., Cohen, K. E., Smith, J. J., Dudley, D., … Morgan, P. J. (2016). Fundamental Movement Skills : An Important Focus Only Leads to a Limited Number, 219–225. Cairney, J., Clark, H. J., James, M. E., Mitchell, D., Dudley, D. A., & Kriellaars, D. (2018). The Preschool Physical Literacy Assessment Tool : Testing a New Physical Literacy Tool for the Early Years, 6(June), 1–9. https://doi.org/10.3389/fped.2018.00138 Carson, H. J., Collins, D., & Carson, H. J. (2016). The fourth dimension : A motoric perspective on the anxiety – performance relationship The fourth dimension : A motoric perspective on the anxiety – performance relationship, 9858(February), 0–21. https://doi.org/10.1080/1750984X.2015.1072231 Griffiths, A., Toovey, R., Morgan, P. E., Spittle, A. J., & Pe, M. (2018). Psychometric properties of gross motor assessment tools for children : a systematic review, 1–14. https://doi.org/10.1136/bmjopen-2018-021734 Hasnida. (2014). Analisis Kebutuhan Anak Usia Dini. Jakarta: Luxima. Helmawati. (2015). Mengenal dan Memahami PAUD. Bandung: PT Remaja Rosdakarya. Hiryanto. (2013). Pemetaan Tingkat Pencapaian Mutu Program Pendidikan Anak Usia Dini (Paud) Di Propinsi DIY. Yogyakarta. Retrieved from https://www.google.com/url? Hurlock, E. B. (1999). Perkembangan Anak Jilid I. (Erlangga, Ed.). jakarta. Loprinzi, P. D., Davis, R. E., & Fu, Y. (2015). Early motor skill competence as a mediator of child and adult physical activity Early / Middle Childhood. PMEDR, 2, 833–838. https://doi.org/10.1016/j.pmedr.2015.09.015 Malina, R. M. (2003). Motor Development during Infancy and Early Childhood : Overview and Suggested Directions for Research. International Journal of Sport and Health Science, 2(5), 50–66. Retrieved from http://www.soc.nii.ac.jp/jspe3/index.htm Monnas, L. B. (2018). Insight stories : Looking into teacher support in enhancing scientific thinking skills among pre-school students. Journal of Educational Sciences., 2(1), 19–25. Retrieved from https://www.google.com/url? Pendidikan, M., Kebudayaan, D. A. N., & Indonesia, R. PERATURAN MENTERI PENDIDIKAN DAN KEBUDAYAAN REPUBLIK INDONESIA NOMOR 137 TAHUN 2014 TENTANG STANDAR NASIONAL PENDIDIKAN ANAK USIA DINI (2014). Purna, R. & Kinasih, A. S. (2015). Psikologi Pendidikan Anak Usia Dini. Jakarta: PT. Indeks. Rao, N., Sun, J., Richards, B., Weber, A. M., Sincovich, A., Darmstadt, G. L., & Ip, P. (2018). Assessing Diversity in Early Childhood Development in the East Asia-Pacific. Richard, D. (2013). Aplikasi Teori Pembelajaran Motorik di Sekolah. yogyakarta: Diva Press. Rolina, N., & Muhyidin. (2015). Metode & Media Pembelajaran (jilid 4). In Ensiklopedia Pendidikan Anak Usia Dini. yogyakarta: Pustaka Insan Madani. Sani, N. A., & Yunus, F. (2018). Amalan Perancangan , Pelaksanaan dan Pentaksiran dalam Proses Pengajaran dan Pembelajaran Pranumerasi di Tadika Swasta. Jurnal Pendidikan Malaysia, 43(2), 101–110. https://doi.org/http://dx.doi.org/10.17576/JPEN-2018-43.02-10 Amalan Santioso, L. . (2016). Tes Minat dan Bakat Anak. Jakarta: Penebar Swadaya Group. Suyadi. (2014). Manajemen PAUD (TPA-KB-TK/RA). yogyakarta: Pustaka Pelajar.

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Kolaczko, Jensen G., Derrick M. Knapik y Michael J. Salata. "Peri-operative pain management in hip arthroscopy: a systematic review of the literature". Journal of Hip Preservation Surgery 6, n.º 4 (7 de noviembre de 2019): 353–63. http://dx.doi.org/10.1093/jhps/hnz050.

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Abstract The purpose of this article was to review current literature on peri-operative pain management in hip arthroscopy. A systematic review of the literature on pain control in hip arthroscopy published January 2008 to December 2018 was performed. Inclusion criteria consisted of English language or articles with English translations, subjects undergoing hip arthroscopy with documented peri-operative pain control protocols in studies reporting Level I to IV evidence. Exclusion criteria were non-English articles, animal studies, prior systematic review or meta-analyses, studies not reporting peri-operative pain control protocols, studies documenting only pediatric (<18 years of age) patients, studies with Level V evidence and studies including less than five subjects. Statistical analysis was performed to assess pain protocols on narcotic consumption in PACU, VAS score on discharge, time to discharge from PACU and incidence of complications. Seventeen studies were included, comprising 1674 patients. Nerve blocks were administered in 50% of patients (n = 838 of 1674), of which 88% (n = 740 of 838) received a pre-operative block while 12% (n = 98 of 838) post-operative block. Sixty-eight complications were recorded: falls (54%, n = 37), peripheral neuritis (41%, n = 28), seizure (1.5%, n = 1), oxygen desaturation and nausea (1.5%, n = 1) and epidural spread resulting in urinary retention (1.5%, n = 1). No significant differences in narcotic consumption, VAS score at discharge, time until discharge or incidence of complication was found based on pain control modality utilized. No statistically significant difference in PACU narcotic utilization, VAS pain scores at discharge, time to discharge or incidence of complications was found between peri-operative pain regimens in hip arthroscopy.

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Martin, M. G. y A. F. Cashen. "SEER analysis of subcutaneous panniculitis-like T-cell lymphoma (SPTL)". Journal of Clinical Oncology 27, n.º 15_suppl (20 de mayo de 2009): e19527-e19527. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e19527.

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e19527 Background: The uncommon nature of SPTL has hampered its clinical characterization. The EORTC described 83 cases of SPTL across 8 centers and suggested a difference in prognosis between patients with alpha/beta (AB) SPTL, who were predominantly younger (median age 36 y) and those with gamma/delta (GD) SPTL, who had a median age of 59 years (1–Blood 2008; 111: 838–45). But regional differences in the frequency of SPLT have also been suggested, with its frequency >2x higher in North America than Europe (2–J Clin Oncol 2008 26: 4121–30). We hypothesized that there may be differences in the presentation between SPTL in Europe and North America. Methods: Analysis of the SEER 17 Nov 2007 (1973–2005) database was conducted with SEER Stat version 6.4.4 and GraphPad Prism 5. Cases of SPTL were defined by the ICD-O-3 code 9708. We also analyzed outcomes for patients < and ≥ 50y at diagnosis. Results: 64 patients were identified with SPTL. The median age was 53y (range 2–83); 28 were <50y and 36 were ≥50y. 19 (30%) patients were male, 45 were female; 44 (69%) patients were white, 13 were black and 7 were Asian. Stage was available on 27 patients: 16 (59%) were Stage I/II and 11 were stage III/IV. There was no difference in gender, ethnicity or stage distribution between those < 50 and ≥ 50. Information on B symptoms was available on 20 patients, 11 (55%) of whom had B symptoms. 5-year lymphoma specific survival was 51%; 5-year OS was 41%. Median OS for patients < 50 was 60 months compared to 12 months for patients ≥50 (G-B-W p=0.0183). Lymphoma specific survival was also significantly longer in the younger patients (G-B-W p=0.0015). Conclusions: In the SEER database, outcome of SPTL is strongly correlated with age. This result suggests a different biology between younger and older patients with SPTCL, possibly because the AB- subtype is more prevalent in younger patients, as reported by the EORTC. As well as differences in the overall frequency of SPTL (2), there may be geographic differences in the distribution of subtypes. [Table: see text] No significant financial relationships to disclose.

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Liu, Ruiyin, Jian Tao y Dehui Wang. "An Inference Methodology for Selecting and Clustering Genes Based on Likelihood Ratio Test". International Journal of Pattern Recognition and Artificial Intelligence 30, n.º 08 (17 de julio de 2016): 1650019. http://dx.doi.org/10.1142/s0218001416500191.

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Peddada et al. (Gene selected and clustering for time-course and close-response microarray experiments using order-restricted inference, Bioinformatics 19 (2003): 834–841) proposed a new method for selecting and clustering genes according to their time-course or dose-response profiles. Their method necessitates the assumption of a constant variance through time or among dosages. This homoscedasticity assumption is, however, seldom satisfied in practice. In this paper, via the application of Shi’s algorithms and a modified bootstrap procedure (N. Z. Shi, Maximum likelihood estimation of means and variances from normal populations under simulations order restrictions (J. Multivariate Anal. 50 (1994) 282–293), we proposed a generalized order-restricted inference method which releases the homoscedasticity restriction. Simulation results show that procedures considered in this paper as well as those by Peddada et al. (Gene selected and clustering for time-course and close-response microarray experiments using order-restricted inference, Bioinformatics 19 (2003) 834–841) are generally comparable in terms of Type I error rate while our proposed algorithms are usually more powerful.

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Canovas, S., M. Aviles y P. Coy. "289 EFFECT OF NEURAMINIDASE AND MANNOSIDASE IN THE BOVINE IN VITRO FERTILIZATION". Reproduction, Fertility and Development 19, n.º 1 (2007): 260. http://dx.doi.org/10.1071/rdv19n1ab289.

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Sperm binding to the ZP is considered a carbohydrate- mediated process (Benoff 1997 Mol. Hum. Reprod. 3, 599–637, 827–837, 839–846). In bovine species, evidence that mannose could be a specific residue involved in bovine sperm-ZP binding has been reported (Amari et al. 2001 Mol. Reprod. Dev. 59, 221–226). Recently, Velasquez et al. (2006 Mol. Reprod. Dev. in press) showed that bovine sperm-ZP binding is mediated by α-2,3-linked sialic acid and that the use of a sialidase (neuraminidase) strongly decreased the sperm-ZP binding and fertilization. IVF with oocytes previously incubated with mannosidase or neuraminidase to compare the role played by mannose and sialic residues in the sperm-ZP binding and fertilization was performed. These specific glycosidase enzymes should remove mannose and sialic acid residues in the ZP. The in vitro-matured bovine oocytes were pre-incubated with the following: (i) mannosidase (1, 2, and 10 IU mL-1), (ii) neuraminidase (1 IU mL-1), and (iii) no enzyme (control group) in maturation medium (Edwards and Hansen 1996 Biol. Reprod. 55, 341–346) for 1 h. After the enzymatic treatment, the oocytes were rinsed 3 times in fresh fertilization medium and were inseminated in IVF-TALP with frozen bull semen processed by a Percoll gradient at a concentration of 1 � 105 cells mL-1. The oocytes were co-incubated with spermatozoa for 18–22 h at 38.5�C in a 5% CO2 atmosphere. Then, the oocytes were washed in PBS twice and fixed in glutaraldehyde. The samples were stained with Hoechst 33342 solution and assessed under an epifluorescence microscope to determine the presence of sperm head in the cytoplasm or pronucleus formation. The data were presented as the mean penetration rate � SEM, and the variables were analyzed by 1-way ANOVA (SPSS 11.0; SPSS Inc., Chicago, IL, USA). The results showed that neuraminidase treatment (1 IU mL-1) strongly decreased the penetration percentages from 62% (control group) to 32% (neuraminidase group). When the mannosidase treatment was used, the percentage of penetration was similar to that of the control for both the 1 IU mL-1 (66%) and the 2 IU mL-1 (55%) groups. In the group in which 10 IU mL-1 were used, the oocytes became degenerated, but a control experiment demonstrated that the degeneration was due to the enzyme excipient at that concentration. The neuraminadase results obtained are in accordance with the results obtained by Velasquez et al. (in press). However, mannosidase had no effect, although Amari et al. (2001) reported that mannose could be a specific residue involved in the bovine sperm-ZP binding. Tanghe et al. (2004 Mol. Reprod. Dev. 68, 492–499) showed that the p-aminophenyl derivative of d-mannose affects the sperm–oocyte fusion at the oolema level but not the number of spermatozoa bound to the zona pellucida. When they observed the effect of glycoproteins and carbohydrates on bovine oocyte penetration, sialic acid 10 mM caused 20% inhibition of penetration. According to our results and those previously reported (Tanghe et al. 2004; Velasquez et al. in press), we propose that the sialic acid is a main receptor at the bovine ZP level for bull spermatozoa. This study was supported by the Spanish Ministry of Education and Science (AGL2006-03495 and BMC 2004-05568) and the Seneca Foundation of the Murcia Regional Government (03018/PI/05).

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Phillips, John D., Hector A. Bergonia, Christopher A. Reilly, Michael R. Franklin y James P. Kushner. "The Uroporphomethene Inhibitor Causitive for Porphyria Cutanea Tarda (PCT) Is Generated by Oxidation of Hydroxymethylbilane (HMB)". Blood 112, n.º 11 (16 de noviembre de 2008): 3454. http://dx.doi.org/10.1182/blood.v112.11.3454.3454.

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Abstract Porphyria cutanea tarda (PCT) is caused by a uroporphomethene (UPN) inhibitor of uroporphyrinogen decarboxylase (Phillips, JD et al, Proc Natl Acad Sci U S A. 2007 104(12):5079–84). In the absence of the inhibitor very little uroporphyrin (URO) is secreted in the urine and the excreted URO is predominantly the isomer-III (URO-III). In contrast, in patients with PCT and mice with experimental PCT the predominant porphyrin excreted in urine is uroporphyrin-I (URO-I). Direct measurements of uroporphyrinogen III synthase activity (UIIIS) in mice with PCT have shown no reduction in activity indicating that an alternate mechanism is responsible. We hypothesized that oxidation of a single bridge carbon of HMB, the product of the porphobilinogen deaminase reaction, is the initial event leading to the porphomethene. Our structural data indicate that oxidized HMB cannot serve as a substrate for UIIIS (Schubert, HL et al, Biochem J. 2008 47(33):8648–55) but can non-enzymatically cyclize to form UPN I. UPN I would then serve as the inhibitor of uroporphyrinogen decarboxylase but and then be fully oxidized to yield URO-I. To test this hypothesis we generated authentic UPN’s I and III. URO’s I and III were reduced with palladium on carbon to yield uroporphyrinogens (Uro’gen) I and III. UPN’s I and III were then generated by controlled photo-oxidation of the corresponding Uro’gens. We then utilized LC-MS to separate and characterize the synthesized UPN’s. Retention times of the two compounds differed by approximately 1 min (UPN III elutes prior to UPN I) but the profile of the daughter ions derived from the UPN’s (molecular mass 835 Da) was identical. The same approach was applied to clarified liver cytosol from mice with experimental PCT. The retention time of the 835 Da UPN identified in mouse liver cytosol corresponded to that of the synthesized UPN I and yielded identical daughter ions. These data support the hypothesis that oxidation of HMB leads to formation of UPN I in vivo. This is concordant with our view that UPN I serves both as the inhibitor of URO-D and as the source of the excess URO-I found in PCT.

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Guerra, João y Julia S. Guivant. "Apresentação - Dossiê "Leigos e peritos na governança socioambiental: perspectivas nas duas margens do Atlântico"". Política & Sociedade 19, n.º 44 (30 de abril de 2020): 7–16. http://dx.doi.org/10.5007/2175-7984.2020v19n44p7.

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AGYEMAN, J. et al. Trends and Directions in Environmental Justice: From Inequity to Everyday Life, Community, and Just Sustainabilities. Annual Review of Environmental Resources, v. 41, p. 6.1-6.20, 2016.BOYLE, A. Human rights and the environment: where next? The European Journal of International Law, v. 23, n. 3, p. 613-642, 2012.CRUTZEN, P. J.; STOERMER, E. F. The ‘Anthropocene’. Global Change Newsletter, v. 41, p. 17-18, 2000.DRYZEK, J. S.; NORGAARD, R. B.; SCHLOSBERG, D. Climate-Challenged Society. Oxford: Oxford University Press, 2013.GONÇALVES, A.; GUERRA, J. Experimentar ciência e cidadania: o caso EuroLifeNet. Atas do VI Congresso Português de Sociologia: Mundos Sociais: Saberes e Práticas. Lisboa: Associação Portuguesa de Sociologia, 2008.GUERRA, J.; LOURENÇO, L. C. The 2030 Agenda: trends of transition toward sustainability. In: DELICADO, A.; DOMINGOS, N.; SOUSA, L. (org.). The Diverse Worlds of Sustainability. Lisboa: Imprensa de Ciências Sociais, 2018. p. 53-85.GUDOWSKYA, N.; ROSA, A. Bridging epistemologies – Identifying uniqueness of lay and expert knowledge for agenda setting. Futures, v. 109, p. 24-38, 2019.GUIVANT, J. S. O Legado de Ulrich Beck. Ambiente & Sociedade, v. 19, n. 1, p. 229-240, 2016.HOLANDA, S. B. Raízes do Brasil. São Paulo: Cia. das Letras, 2006.IPCC. Climate Change 2014: Synthesis Report. Contribution of Working Groups I, II and III to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change. Genebra: IPCC, 2014.IPCC. Global warming of 1.5°C. An IPCC Special Report on the impacts of global warming of 1.5°C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to the threat of climate change, sustainable development, and efforts to eradicate poverty. Genebra: World Meteorological Organization, 2018.KAISER J. Ecologists on a mission to save the world. Science, v. 287, p. 1188-1192, 2000.LIKENS, G. E. The role of science in decision making: does evidence-based science drive environmental policy? Frontiers in Ecology and the Environment, v. 8, n. 6, p. e1-e9, 2010.LIMA, S. et al. Produção e consumo de produtos orgânicos no mundo e no Brasil. Rio de Janeiro: Instituto de Pesquisa Econômica Aplicada, 2020.PIKETTY, T.; SAEZ, E. Inequality in the long run. Science, v. 344, n. 6186, p. 838-843, 2014.PNUD. Relatório de Desenvolvimento Humano 2011 – Sustentabilidade e Equidade: um Futuro Melhor para Todos. Lisboa: IPAD/PNUD, 2011.REGANOLD, J.; WACHTER, J. Organic agriculture in the twenty-first century. Nature Plants, v. 2, Article 15221, 2016. DOI: 10.1038/NPLANTS.2015.221.TAYLOR, D. Is Environmental Health a Basic Human Right? Environmental Health Perspectives, v. 112, n. 17, p. A1006-A1009, 2004.UN GENERAL ASSEMBLY. Transforming our World: the 2030 Agenda for Sustainable Development - Resolution adopted by the General Assembly on 25 September 2015. Genebra: ONU, 2015.UNCHE. Report of the United Nations Conference of the Human Environment. Stockholm: United Nations Publication, 5-16 June 1972.

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Marques, Lorena Sousa, Tarcisio Costa Lobato y Brena Nascimento Carvalho. "CONVERGENCE TO PARITY: THE ADMISSION OF WOMEN TO THE FORMAL LABOR MARKET IN THE RURAL ENVIRONMENT OF THE CITY OF BELÉM - PA". Revista de Administração e Negócios da Amazônia 13, n.º 4 (30 de diciembre de 2022): 141–60. http://dx.doi.org/10.18361/2176-8366/rara.v13n4p141-160.

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O mercado de trabalho formal passou por mudanças ao longo dos anos, ressignificando o papel da mulher e trazendo novas óticas ao processo produtivo. Este trabalho investiga a possível convergência para a igualdade de gênero nas admissões do mercado de trabalho formal rural da cidade de Belém. Com dados extraídos do CAGED no período de 2004 a 2019, utilizou-se o modelo sazonal autorregressivo integrado de médias móveis – SARIMA. Estimou-se, em média, que haverá igualdade nas admissões na capital do estado do Pará em um cenário otimista (09/2027), em média 09/2037 e pessimista 08/2053. Referências AGÉNOR, P.; CANUTO, O. (2015). Gender equality and economic growth in Brazil: A long-run analysis. Journal of Macroeconomics, 43, 155. AKAIKE, H. A new look at the statistical model identification. IEEE Transactions on Automatic Control., Boston, v.19, n.6, p.716-723, Dec. 1974. AKAIKE, H. Information theory and an extension of the maximum likelihood principle. In Proc. 2nd Inter. Symposium on Information Theory, pp. 267-281, Budapest. 1973. BAYLÃO, André Luis da Silva; SCHETTINO, Elisa Mara Oliveira. A inserção da mulher no mercado de trabalho brasileiro. XI SEGeT-Simpósio de Excelência em Gestão e Tecnologia. Anais do XI Simpósio de Excelência em Gestão e Tecnologia. Resende-Rio de Janeiro, 2014. BARBOSA, Ana Luiza Neves de Holanda. Participação feminina no mercado de trabalho. Boletim Mercado de trabalho brasileiro. (Conjuntura e Análise nº 57). 2014. BARBOSA, Ana Luiza Neves de Holanda; COSTA, Joana Simões de Melo. Oferta de creche e participação das mulheres no mercado de trabalho do Brasil. Boletim Mercado de Trabalho. (Conjuntura e Análise nº 62). 2017. BENERIA, Lourdes. Introducción. La mujer y el género sem la economia: sem panorama general. Gender, Development and Globalization. Copyright, 2004. BORDALO, C. A. Os caminhos da política: o sindicalismo rural e os movimentos de mulheres trabalhadoras rurais em Pernambuco. 2011. 158 f. Dissertação (Mestrado em Ciências) – Programa de Pós-Graduação em Ciências Sociais em Desenvolvimento, Agricultura e Sociedade, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro, 2011. BUENO, R. L. S. Econometria de séries temporais. São Paulo: Cengage Learning, 2011. 320p. CAMARGO, Thatianne Pinto. Os desafios encontrados na inserção da mulher no agronegócio. 2018. 41 f. TCC (Graduação) - Curso de Administração, Faculdade Evangélica de Jaraguá, Jaraguá, 2018. Disponível em: http://repositorio.aee.edu.br/bitstream/aee/1055/1/2018-1_TCC_CamargoThatiannePinto.pdf. Acesso em: 25 out. 2021. COSTA, J. S. M. Determinantes da participação feminina no mercado de trabalho brasileiro. 2007. Tese (Mestrado em Economia) – Universidade de Brasília, Brasília, 2007. DEERE, C. D. Os direitos da mulher à terra e os movimentos sociais rurais na reforma agrária brasileira. Estudos Feministas, Florianópolis, v. 12, n. 1, p. 175-204, jan./abr. 2004. DEERE, C. D. ; LEÓN, M.O empoderamento da mulher. Porto Alegre: Ed. da UFRGS, 2002. EHLERS, R. S. Análise de séries temporais. In: Notas de aula de séries temporais. São Paulo: USP, 2007. Disponível em: http://www.each.usp.br/rvicente/AnaliseDeSeriesTemporais.pdf. Elliott, G., Rothenberg, T. J. & Stock, J. H. Efficient tests for an autoregressive unit root. Econometrica 64: 813-836, 1996. ESTIVAL, K. G. S. Reflexões sobre o trabalho das mulheres rurais no brasil na perspectiva da economia feminista. Revista Caribeña de Ciencias Sociales, v. 1, p. 12-20, 2014. FAO (Organização das Nações Unidas para a Agricultura e a Alimentação). (2011), O Estado Mundial de la Agricultura y la Alimentación. Roma, FAO, parte I. FARIA, Nalu; NOBRE, Miriam (Orgs.). Economia feminista. São Paulo: SOF, 2002. FAVA, V. Manual de econometria. In: VASCONCELOS, M. A. S.; D. São Paulo: Editora Atlas, 2000. FERREIRA, Pedro Guilherme Costa; MATTOS, Daiane Marcolino. Modelo SARIMA. In: Anna Carolina Barros et al. (org.). Análise de séries temporais em R: um curso introdutório. Rio de Janeiro: Elsevier, 2018. Cap. 4. p. 121-2143.

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Font, M. I., M. Juárez, O. Martínez y C. Jordá. "Current Status and Newly Discovered Natural Hosts of Tomato infectious chlorosis virus and Tomato chlorosis virus in Spain". Plant Disease 88, n.º 1 (enero de 2004): 82. http://dx.doi.org/10.1094/pdis.2004.88.1.82a.

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Tomato chlorosis virus (ToCV) and Tomato infectious chlorosis virus (TICV) are emergent whitefly-transmitted criniviruses. ToCV and TICV were detected in Spain in 2000 (2) and 2001 (1), respectively. Both viruses infect tomato (Lycopersicon esculentum Mill) crops and cause symptoms of foliar chlorosis. ToCV is prevalent along the southern and eastern regions of Spain (provinces of Sevilla, Málaga, Almería, Murcia, Alicante, and Castellón), Balearic (Mallorca), and the Canary Islands (Tenerife and Gran Canaria). However, TICV only has been detected in the provinces of Murcia, Alicante, and Castellón in Spain. During the summer and autumn of 2002, abnormal interveinal reddening, yellowing symptoms, or both, were observed in plants of Chenopodium album L., C. murale L., and Solanum nigrum L. growing in or around tomato fields in Murcia and Almería provinces. To study the alternative hosts that may serve as virus reservoirs in areas where these viruses are prevalent, 62 samples of 42 common weed species were analyzed by reverse transcription-polymerase chain reaction using specific primers for ToCV and TICV (1). The 439-bp ToCV-specific DNA fragment was amplified in two S. nigrum samples from Alicante and Murcia provinces, and the 501-bp TICV-specific DNA fragment was amplified in one C. murale sample from Murcia, as well as in three C. album samples from Murcia and Alicante provinces. The DNA fragment amplified from the ToCV isolate was sequenced and showed 99 to 98% identity with the ToCV isolates (GenBank Accession Nos. AY048854 and AF234029) from Italy and Portugal, respectively. The DNA fragment amplified from TICV isolates were sequenced and showed 98% identity with the TICV isolate from Spain (GenBank Accession No. AF479662), confirming the diagnosis. Although the number of samples is not sufficient to conclude that we know, in a precise way, the role of weed reservoirs in TICV and ToCV epidemics in Spain, this study might contribute to a better understanding of the epidemiology of these viruses. To our knowledge this is the first report of these weeds as natural hosts of ToCV and TICV in Spain. References: (1) M. I. Font et al. Plant Dis. 86:696, 2002. (2) J. Navas-Castillo et al. Plant Dis. 84:835, 2000.

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Patterson, Dr Laura. "Detection of Chlamydia trachomatis infection in early pregnancy using self-administered vaginal swabs and first-pass urines: a cross-sectional community-based survey. Oakeshott P, Hay P, Hay S, et al. Br J Gen Pract 2002; 52 (483): 830-832". Journal of Family Planning and Reproductive Health Care 29, n.º 1 (1 de enero de 2003): 41. http://dx.doi.org/10.1783/147118903101197025.

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Batista Neto, Alberto Leopoldo. "O ensino de filosofia e a ideia de uma universidade". Trilhas Filosóficas 12, n.º 1 (24 de octubre de 2019): 231–51. http://dx.doi.org/10.25244/tf.v12i1.34.

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Resumo: Autor de uma obra filosófica abrangente, Alasdair MacIntyre manifesta um interesse profundo pelo tema da educação, tendo refletido, em particular, seriamente sobre a universidade. Sua concepção de universidade é fortemente influenciada por aquela defendida por John Henry Newman no século XIX, e se relaciona intimamente, tanto quanto para Newman, com a sua compreensão sobre a filosofia. Partindo de tal concepção, é possível refletir sistematicamente sobre a questão do ensino de filosofia, tanto no interior da vida universitária quanto nas relações desta última com a sociedade e a cultura em geral, inclusive com um foco particular sobre a realidade brasileira. Palavras-chave: Alasdair MacIntyre (1929-). John Henry Newman (1801-1890). Universidade. Ensino de filosofia. Abstract: Authoring a comprehensive philosophical oeuvre, Alasdair MacIntyre manifests a profound interest on the subject of education, having produced in particular a serious reflection on the theme of the university. His conception of a university is strongly influenced by that of John Henry Newman in the 19th century, and is intimately related, as much as with Newman’s, to his understanding of philosophy. Beginning with such a conception, it is possible to systematically meditate on the matter of the teaching of philosophy, within the university walls as well as at its general cultural and social boundaries, including a particular focus on Brazilian reality. Keywords: Alasdair MacIntyre (1929-). John Henry Newman (1801-1890). University. Philosophy teaching. REFERÊNCIAS ARRIOLA, Claudia Ruiz. Tradición, Universidad y Virtud: Filosofia de la Educacion Superior en Alasdair MacIntyre. Pamplona: EUNSA, 2000. ARISTÓTELES. Ethica Nicomachea. In: MCKEON, Richard (Org.). The Basic Works of Aristotle. New York: The Modern Library, 2001. ARTIGAS, Mariano. Mind of the Universe: Understanding Science and Religion. Philadelphia: Templeton Foundation, 1999. BISHOP, Jeffrey P. Waiting for St. Benedict among the Ruins: MacIntyre and Medical Practice. Journal of Medicine and Philosophy, 36 (2011), p. 107-113. BRASIL. Lei de Diretrizes e Bases da Educação Nacional. Lei nº 9.394, 20 dez. 1996. Brasília: Diário Oficial da União, 1996. BRASIL. Lei nº 13.415, 16 fev. 2017. Brasília: Diário Oficial da União, 2017. BREWER, Kathryn Balstad. Management as a Practice: A Response to Alasdair MacIntyre. Journal of Business Ethics, 16 (1997), p. 825-833. CAVANAUGH, William T. The Myth of Religious Violence: Secular Ideology and the Roots of Modern Conflict. New York: Oxford University Press, 2009. CERLETTI, Alejandro. O ensino de filosofia como problema filosófico. Trad. Ingrid Müller Xavier. Belo Horizonte: Autêntica, 2009. CROSS, Bryan R. MacIntyre on the Practice of Philosophy and the University. American Catholic Philosophical Quaterly, 88, 4 (2014), p. 751-766. CUNHA, Luiz Antonio. A universidade temporã: o ensino superior, da Colônia à era Vargas. 3. ed. São Paulo: Ed. UNESP, 2007. DUNNE, Joseph. Arguing for Teaching as a Practice: A Reply to Alasdair MacIntyre. Journal of Philosophy of Education, 37, 2 (2003), p. 353-369. DUNNE, Joseph. Newman Now: Re-Examining the Concepts of ‘Philosophical’ and ‘Liberal’ in The Idea of a University. British Journal of Educational Studies, 54, 4 (2006), p. 412-428. DEINA, Wanderley José. Filosofia no ensino médio: considerações sobre a reforma educacional brasileira a partir do pensamento de Theodor Adorno. Sofia, 6, 3 (2017), pp. 5-25. FÓRUM NACIONAL PERMANENTE DO ENSINO RELIGIOSO. Parâmetros Curriculares Nacionais para o Ensino Religioso. 3. ed. São Paulo: Ave Maria, 1997. GALLO, Sílvio. A filosofia e seu ensino: conceito e transversalidade. Ethica, 13, 1 (2006), p. 17-35. GOMES, Laécio de Almeida. Filosofia como educação moral: a filosofia da educação em Alasdair MacIntyre. Saberes, 1, 6 (2011), p. 65-76. GOMES, Roberto. Crítica da razão tupiniquim. 11. ed. São Paulo: FTD, 1994. GONTIJO, Pedro. O ensino da filosofia no Brasil: algumas notas sobre avanços e desafios. Perspectivas, 2, 1 (2017), p. 3-17. GOVERNO DO ESTADO DO PARANÁ. Diretrizes Curriculares da Educação Básica – Ensino Religioso. Curitiba: Secretaria de Estado da Educação do Paraná, 2008. HALDANE, John. MacIntyre’s Thomist revival: What’s next? In: HALDANE, John. Faithful Reason: Essays Catholic and Philosophical. London: Routledge, 2004, p. 15-30. KERR, Clark. The Uses of a University. 5. ed. Cambridge: Harvard University Press, 2001. LAMBETH, Edmond B. Waiting for a New St. Benedict: Alasdair MacIntyre and the Theory and Practice of Journalism. Journal of Mass Media Ethics, 5, 2 (1990), p. 75-87. MACINTYRE, Alasdair. The Idea of an Educated Public. In: HAYDON, Graham (Org.). Education and Values: The Richard Peters Lectures. London: University of London Press, 1987, p. 15-35. MACINTYRE, Alasdair. Three Rival Versions of Moral Enquiry: Encyclopaedia, Genealogy, and Tradition. Indiana: University of Notre Dame Press, 1990a. MACINTYRE, Alasdair. First Principles, Final Ends and Contemporary Philosophical Issues. Milwaukee: Marquette University, 1990b. MACINTYRE, Alasdair. Justiça de quem? Qual racionalidade? Trad. Marcelo Pimenta Marques. São Paulo: Loyola, 1991. MACINTYRE, Alasdair. Dependent Rational Animals: Why Human Beings Need the Virtues. Peru (Il): Open Court, 1999. MACINTYRE, Alasdair. Depois da virtude: um estudo em teoria moral. Trad. Jussara Simões. Bauru (SP): EDUSC, 2001. MACINTYRE, Alasdair. Moral Philosophy and Contemporary Social Practice: What Holds Them Apart? In: MACINTYRE, Alasdair. The Tasks of Philosophy: Selected Essays, Volume I. New York: Cambridge University Press, 2006, p. 104-122. MACINTYRE, Alasdair. God, Philosophy, Universities: A Selective History of the Catholic Philosophical Tradition. Lanham: Rowman & Littlefields, 2009a. MACINTYRE, Alasdair. The Very Idea of a University: Aristotle, Newman and Us. The New Blackfriars, 91, 1031 (2010), p. 4-19 (2010a) MACINTYRE, Alasdair. On Not Knowing Where You Are Going. Proceedings and Addresses of the American Philosophical Association, 84, 2 (2010), p. 61-74. (2010b) MACINTYRE, Alasdair; DUNNE, Joseph. Alasdair MacIntyre on Education: In Dialogue with Joseph Dunne. Journal of Philosophy of Education, 36, 1 (2002), p. 1-19. MADARIAGA CÉZAR, Manuel García de. La educación en Alasdair MacIntyre: contextos y proyectos. Tese de doutorado. 2009. Pamplona. Facultad Eclesiástica de Filosofía. Universidad de Navarra. MICHEL, Andrew A. Psychiatry After Virtue: A Modern Practice in the Ruins. Journal of Medicine and Philosophy, 36 (2011), p. 170-186. NEWMAN, John Henry. Prefácio. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001a, p. 59-71. NEWMAN, John Henry. Introdutório. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001b, p. 59-71. NEWMAN, John Henry. Teologia, ramo do conhecimento. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001c, p. 73-89. NEWMAN, John Henry. Relação da teologia com outros ramos do conhecimento. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001d, p. 91-110. NEWMAN, John Henry. Relação dos outros ramos do conhecimento com a teologia. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001e, p. 111-130. NEWMAN, John Henry. Conhecimento, fim em si mesmo. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001f, p. 131-148. NEWMAN, John Henry. O conhecimento em relação à capacidade profissional. In: TURNER, Frank M. (Org.). Newman e a idéia de uma universidade. Trad. Gilson César Cardoso de Sousa. Bauru (SP): EDUSC, 2001g, 169-188. OLIVE, Arabela Campos. Histórico da educação superior no Brasil. In: SOARES, Maria Susana Arrosa (Org.). A educação superior no Brasil. Brasília: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, 2002, pp. 31-42. PAVIANI, Jayme. Interdisciplinaridade: conceitos e distinções. 2. ed. Caxias do Sul (RS): Educs, 2008. PINHO, Rozana Isabel Brázio Valente. O ensino de filosofia no Brasil: considerações históricas e político-legislativas. Educação e Filosofia Uberlândia, 28, 56, (2014), p. 757-771. ROHDEN, Valerio (Org.). Idéias de universidade. Canoas: Ed. ULBRA, 2002. ROSSI, Paolo. O Nascimento da Ciência Moderna na Europa. Trad. Antonio Angonese. Bauru (SP): EDUSC, 2001. SANTIAGO, Maria Francilene Câmara; SANTOS, Ivanaldo; SANTOS, Simone Cabral Marinho. Notas sobre o ensino e a iniciação científica na Educação Básica. In: SANTOS, Ivanaldo; SANTIAGO, Maria Francilena Câmara; SANTOS, Simone Cabral Marinho (Org.). Ciência na escola: fazendo, vivendo e experimentando. Curitiba: CRV, 2015, p. 19-32. SANTOS, Ivanaldo. O método de pesquisa em Tomás de Aquino. In: SANTOS, Ivanaldo. (Org.). Método de pesquisa: perspectivas filosóficas. Mossoró (RN): Edições UERN, 2010, p. 25-36. SANTOS, Ivanaldo. A presença de Tomás de Aquino nas universidades. Aquinate, 21 (2013), p. 14-24. SANTOS, Ivanaldo. Ensino religioso: possibilidade de vivência e de convívio da diversidade religiosa do Brasil. In: SILVEIRA, Ronie Alexandro Teles; LOPES, Marcos Carvalho (Org.). A religiosidade brasileira e a filosofia. Porto Alegre: Fi, 2016, p. 252-268. SELLMAN, Derek. Alasdair MacIntyre and the Professional Practice of Nursing. Nursing Philosophy, vol. 1 (2000), p. 26-33. SILVA, Raimundo Fábio da; SANTOS, Ivanaldo. A arte, sua função e a necessidade de seu ensino enquanto disciplina curricular e reflexão filosófica. Revista Ensino Interdisciplinar, 2 (2016), p. 30-41. SNOW, C. P. As duas culturas e um segundo olhar. Trad. Renato Rezende Neto. São Paulo: EDUSP, 1993. STOLZ, Steven A. Alasdair MacIntyre, Rationality and Education: Against Education of Our Age. Cham (Switzerland): Springer, 2019. WAIN, Kenneth. MacIntyre: Teaching, Politics and Practice. Journal of Philosophy of Education, 37, 2 (2003), p. 225-239. WEINBERG, Justin. Notre Dame Philosophers Issue Statement on Threats to Philosophy at Univ. of St. Thomas Houston. Daily Nous. 24 maio 2017. Disponível em: http://dailynous.com/2017/05/24/notre-dame-philosophers-issue-statement-threats-philosophy-univ-st-thomas-houston/. Acesso em: 17 jun. 2019.

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Engelbrecht, M., J. Joubert y J. T. Burger. "First Report of Aster Yellows Phytoplasma in Grapevines in South Africa". Plant Disease 94, n.º 3 (marzo de 2010): 373. http://dx.doi.org/10.1094/pdis-94-3-0373a.

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For many years phytoplasma diseases have caused serious losses in most of the major grape-growing regions of the world, except South Africa, where a mixed phytoplasma infection was first reported in 2006 (1). During the early growing season of 2006, symptoms consistent with phytoplasma disease were observed in vineyards in the Olifants River Valley. Symptoms included yellowing of leaves, incomplete lignification of shoots, shortening of internodes, and the abortion of growth tips and immature bunches. Symptomatic shoots and leaves from grapevine cultivars (Merlot, Shiraz, Cabernet Sauvignon, Ruby Cabernet, Pinotage, Corinth, Chardonnay, Columbar, Chenin blanc, Sauvignon blanc, Sultana, and Regal) were collected during the early growing season (November) of 2006, 2007, and 2008. Total DNA was extracted from 32 of these samples (from single plants in the same vineyards over the 3 years) with the Invisorb Spin Plant Mini Kit (Invitek, Berlin, Germany) and tested by nested PCR using two universal primer pairs, P1/P7 and R16F2n/R16R2 (3). The first round of PCR of the 2006 samples yielded 1.8-kb fragments for 17 of the samples, while the nested PCR yielded an additional seven positive samples, confirming the necessity of nested PCR for reliable diagnosis. A similar trend was observed in the 2007 and 2008 PCR test results. All asymptomatic plants, which were included as negative controls, and water controls were negative by nested PCR. Twenty-four 1,245-bp amplicons, generated by nested PCR, were excised from gels, purified with a NucleoSpin Extract II Kit (Macherey-Nagel, Düren, Germany) and directly sequenced. Sequence data was compiled with the BioEdit Version 7.0.4.1 sequence alignment editor software (2), aligned using ClustalW Version 1.4 (4), and a consensus sequence was generated (GenBank Accession No. GQ365729). A BLAST search of the NCBI GenBank database using the individual sequences revealed high sequence identities (≥99%) with the aster yellows phytoplasma group (16SrI) and specifically with the subgroup 16SrI-B. In a comparison of the sequences of the 1.2-kb PCR fragments of 24 local samples with each other, sequence identities of ~99% were observed. These results clearly illustrate that all vines screened were infected with the same phytoplasma. Single nucleotide differences observed between different isolates may indicate the presence of closely related sequence variants of this phytoplasma. Aster yellows occurs worldwide and has been reported to infect grapevine–South Africa can now be added to this list. During the three seasons of our study, the area in which symptomatic vineyards were observed increased significantly, indicating spread by a biological vector. Moreover, infected vineyards were noticed in two other South African grape-growing regions. In contrast to the previous report, which reported a mixed infection of phytoplasmas of groups 16SrXII-A and 16SrII-B (1), PCR screening and sequencing of more than 40 individual samples from these areas confirmed these all to be infected with aster yellows phytoplasma only. To our knowledge, this is the first report of the detection and identification of an aster yellows phytoplasma causing grapevine yellows disease in South Africa. References: (1) S. Botti and A. Bertaccini. Plant Dis. 90:1360, 2006. (2) T. A. Hall. Nucleic Acids. Symp. Ser. 41:95, 1999. (3) I.-M. Lee et al. Phytopathology 83:834, 1993. (4) J. D. Thompson et al. Nucleic Acids Res. 22:4673, 1994.

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Silvianti, Fitrilia, Dwi Siswanta, Nurul Hidayat Aprilita y Agung Abadi Kiswandono. "ADSORPTION CHARACTERISTIC OF IRON ONTO POLY[EUGENOL-CO-(DIVINYL BENZENE)] FROM AQUEOUS SOLUTION". Jurnal Natural 17, n.º 2 (23 de septiembre de 2017): 108. http://dx.doi.org/10.24815/jn.v17i2.8076.

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A study on the adsorption characteristic of Iron onto Poly[eugenol-co-(divinyl benzene)] (EDVB) from aqueous solution has been conducted. EDVB was produced and characterized by using FTIR spectroscopy. The adsorption was studied by a batch method by considering the factors affecting the adsorption such as initial metal ion concentration, adsorption selectivity, and mechanism of adsorption using a sequential desorption method. The adsorption of Iron onto EDVB followed a pseudo-2 order kinetics model with the rate constant of 0,144 L2 mmol-1 min-1. The adsorption isotherm was studied with Tempkin, Langmuir and Freundlich models. The adsorption capacity (Qmax) obtained by Langmuir isotherms was 250mg.L-1 while the equilibrium value was 0.8 Lmg-1. A competitive adsorption study showed that EDVB is adsorbed selectively towards Iron rather than Chromium, Coppers and Cadmium ions. The interaction type of Iron onto EDVB was determined by a sequential desorption.Keywords: Polyeugenol; divinyl benzene (DVB); adsorption; Iron; FeReferencesAbasi, C. Y.; Abia, A.A.; Igwe, J.C. Adsorption of Iron (III), Lead (II) and Cadmium (II) Ions by Unmodified Raphia Palm (Raphia hookeri) Fruit Endocarp. Environ. Res. 2011, 5 (3), 104-113, ISSN: 1994-5396, Medwell Journals. DOI: 10.3923/erj.2011.104.113Baes, F. C.; Mesmer, R. E. The Hydrolisis of Cations; John Wiley: New York, 1976Bakatula, E.N.; Cukrowska, E.M.; Weiersbye, L.; Mihali-Cozmuta, L.;Tutu, H. Removal of toxic elements from aqueous solution using bentonite modified with L-histidine. Water Sci. Technol.2014, 70 (12),2022-2030, DOI: 10.2166/wst.2014.450Bhattacharyya, K.G.; Gupta, S.S. Adsorption of Fe(III) from Water by Natural and Acid Activated Clays: Studies on equilibrium isotherm, kinetics and thermodynamics of interactions. Adsorption. 2006, 12 (3), 185-204,DOI : 10.1007/s10450-006-0145-0Carmona, M..; Lucas, A.D.; Valverde, J.L.; Velasco, B.; Rodriguez, J.F. Combined adsorption and ion exchange equilibrium of phenol on Amberlite IRA-420.Chem. Eng. J.2006, 117, 155-160, Doi : 10.1016/j.cej.2005.12.013Debnath, S.; Ghosh, U.C. Kinetics, isotherm and thermodynamics for Cr(III) and Cr(VI) adsorption from aqueous solutions by crystalline hydrous titanium oxide. J. Chem. Thermodin. 2008, 40: 67-77, DOI: 10.1016/j.jct.2007.05.014Djunaidi, M.C.; Jumina; Siswanta, D.; Ulbricht, M. Selective Transport of Fe(III) Using Polyeugenol as Functional Polymer with Ionic Imprinted Polymer Membrane Method. Asian J. Chem. 2015, 27 (12): 4553-4562, DOI : 10.14233/ajchem.2015.19228Febriasari, A.; Siswanta, D.; Kiswandono, A.A.; Aprilita, N.H. Evaluation of Phenol Transport Using Polymer Inclusion Membrane (PIM) with Polyeugenol as a Carrier. Jurnal Rekayasa Kimia dan Lingkungan. 2016, Vol. 11, No. 2, 99-106, DOI: 10.23955/rkl.v11i2.5112Foldesova, M.; Dillinger, P.; Luckac, P. Sorption and Desorption of Fe(III) on Natural and chemically modified zeolite. J. Radioanal. Nucl. Chem. 1999, Vol. 242, No. 1 (1999), 227-230, DOI: 10.1007/BF02345926Gupta, V.K.;Sharma, S. Removal of cadmium and zinc from aqueous solutions using mud.Environ. Sci. Technol. 2002, 36: 3612-3617, DOI: 10.1021/es020010vHandayani, D.S. Sintesis kopoli(eugenol-DVB) sulfonat dari Eugenol Komponen Utama Minyak Cengkeh Szygium aromaticum (Synthesis of copoly(eugenol-DVB) sulfonic from main components of eugenol clove oil Szygium aromaticum). Biopharmacy Journal of Pharmacological and Biological Sciences. 2004, 2 (2): 53-57 ISSN: 1693-2242. url : https://eprints.uns.ac.id/id/eprint/856Harimu, L.; Matsjeh, S.; Siswanta, D.; Santosa, S.J. Synthesis of Polyeugenyl Oxyacetic Acid as Carrier to Separate Heavy Metal Ion Fe(III), Cr(III), Cu(II), Ni(II), Co(II), and Pb(II) that Using Solvent Extraction Mehod. Indo. J. Chem. 2009, 9 (2): 261-266.Ho, Y.S.; McKay, G. Pseudo-second Order Model for Sorption Processes. Process. Biochem. 1999, 34, 451-465, DOI: 10.1016/S0032-9592(98)00112-5Ho, Y.S.; McKay, G.; Wase, D.A.J.;Forster, C.F. Study of Sorption Divalent Metal Ions on to Peat. Adsorpt. Sci. Technol. 2000, 18: 639-650. DOI : 10.1260/0263617001493693Indah, S.; Helard, D.;Sasmita, A. Utilization of maize husk (Zea mays L.) as low-cost adsorbent in removal of iron from aqueous solution. Water Sci. Technol. 2016, 73 (12), 2929-2935, DOI: 10.2166/wst.2016.154Kiswandono, A.A.; Siswanta, D.; Aprilita, N.H.; Santosa, S.J. Transport of Phenol through inclusion polymer membrane (PIM) using copoly(Eugenol-DVB) as membrane carries. Indo .J. Chem. 2012, 12 (2): 105-112. Doi : 10.22146/ijc.667Kousalya, N.; Gandhi, M.R.; Sundaram, C.S.; Meenakshi, S. Synthesis of nano-hydroxyapatite chitin/chitosan hybrid bio-composites for the removal of Fe(III).Carbohyd. Polym. 2010, 82: 594-599, DOI:10.1016/j.carbpol.2010.05.013Kumar, K.V.; Porkodi, K.;Rocha, F. Langmuir-Hinshelwood kinetics – A theoretical study, Catalysis Communications. 2008, 9: 82-84, DOI:10.1016/j.catcom.2007.05.019Masel, R.I. Principles Adsorption and Reaction on Solid Surface; John Wiley & Sons: Canada, 1996Moore, J. W.; Pearson, R.G. Kinetics and Mechanism Third Edition; John Wiley & Sons: Canada, 1981.Ngah, W.S.W.; Ghani, S.A.; Kamari, A. Adsorption Behaviour of Fe(II) and Fe(III) Ions in Aqueous Solution on Chitosan and Cross-linked Chitosan Beads. Bioresource. Technol. 2005, 96: 443-450. DOI:10.1016/j.biortech.2004.05.022Rahim, E.A.; Sanda, F.; Masuda, T. Synthesis and Properties of Novel Eugenol-Based Polymers. Polymer Bulletin. 2004, Vol. 5, 93-100, DOI: 10.1007/s00289-004-0272-2Samarghandi, M.R.; Hadi. M.; Moayedi, M.; Askari, F.B. 2009. Two Parameter Isotherms of Methyl Orange Sorption by Pinecone Derived Activated Carbon. Iran. J. Environ. Health Sci. Eng., 6 (4): 285-294.Setyowati, L. 1998. Pengaruh Penambahan Divinil Benzena (DVB) pada Kopolimerisasi Kationik Poli[eugenol-co-(divinil benzena)] dan Sifat Pertukaran Kation Kopoligaramnya (The Effect of divinylbenzene (DVB) Addition to Eugenol-DVB Cationic Copolymerization and Its Use As Cation-Exchanger), Thesis, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Yogyakarta, Indonesia.Shi, T.; Jia, S.; Chen, Y.; Wen, Y.; Du, C.; Guo, H.; Wang, Z. Adsorption of Pb(II), Cr(III), Cu(II), Cd(II) and Ni(II) onto a vanadium mine tailing from aqueous solution. J. Hazard. Mater. 2009, 169: 838-846, DOI: 10.1016/j.jhazmat.2009.04.020Sun, S.;Wang, A. Adsorption Kinetics of Cu(II) Ions Using N,O-Carboxymethyl-Chitosan. J. Hazard. Mater. 2006, B131: 103-111, DOI: 10.1016/j.jhazmat.2005.09.012Sun, S.; Wang, L.;Wang, A. Adsorption Properties of Crosslinked Carboxymethyl-chitosan Resin With Pb(II) as Template Ions. J. Hazard. Mater. 2006, B136: 930-937, DOI: 10.1016/j.jhazmat.2006.01.033Uzun, I.; Guzel, F. Adsorption of Some Heavy Metal Ions from Aqueous Solution by Activated Carbon and Comparison of Percent Adsorption Result of Activated Carbon with those of Some Other Adsorbents. Turk. J. Chem. 2000, 24: 291-297.Zou, X.; Pan, J.; Ou, H.; Wang, X.;Guan, W.; Li, C.; Yan, Y.; Duan, Y. Adsorptive removal of Cr(III) and Fe(III) from aqueous solution by chitosan/attapulgite composites: Equilibrium, thermodynamics and kinetics. Chem. Eng. J. 2011, 167: 112-121, DOI: 10.1016/j.cej.2010.12.009

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Craun, Gunther F., Joan M. Brunkard, Jonathan S. Yoder, Virginia A. Roberts, Joe Carpenter, Tim Wade, Rebecca L. Calderon, Jacquelin M. Roberts, Michael J. Beach y Sharon L. Roy. "Causes of Outbreaks Associated with Drinking Water in the United States from 1971 to 2006". Clinical Microbiology Reviews 23, n.º 3 (julio de 2010): 507–28. http://dx.doi.org/10.1128/cmr.00077-09.

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SUMMARY Since 1971, the CDC, EPA, and Council of State and Territorial Epidemiologists (CSTE) have maintained the collaborative national Waterborne Disease and Outbreak Surveillance System (WBDOSS) to document waterborne disease outbreaks (WBDOs) reported by local, state, and territorial health departments. WBDOs were recently reclassified to better characterize water system deficiencies and risk factors; data were analyzed for trends in outbreak occurrence, etiologies, and deficiencies during 1971 to 2006. A total of 833 WBDOs, 577,991 cases of illness, and 106 deaths were reported during 1971 to 2006. Trends of public health significance include (i) a decrease in the number of reported outbreaks over time and in the annual proportion of outbreaks reported in public water systems, (ii) an increase in the annual proportion of outbreaks reported in individual water systems and in the proportion of outbreaks associated with premise plumbing deficiencies in public water systems, (iii) no change in the annual proportion of outbreaks associated with distribution system deficiencies or the use of untreated and improperly treated groundwater in public water systems, and (iv) the increasing importance of Legionella since its inclusion in WBDOSS in 2001. Data from WBDOSS have helped inform public health and regulatory responses. Additional resources for waterborne disease surveillance and outbreak detection are essential to improve our ability to monitor, detect, and prevent waterborne disease in the United States.

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RACHOŃ, LESZEK y ANDRZEJ WOŹNIAK. "Zmienność plonowania jarej pszenicy twardej (Triticum durum Desf.) i zwyczajnej (Triticum aestivum ssp. vulgare) w dziesięcioleciu 2009–2018 na terenie Lubelszczyzny". Agronomy Science 75, n.º 1 (1 de abril de 2020): 67–74. http://dx.doi.org/10.24326/as.2020.1.5.

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Przedmiotem opracowania były wyniki uzyskane z wieloletnich ścisłych doświadczeń polowych prowadzonych w latach 2009–2018 w Katedrze Technologii Produkcji Roślinnej i Towaroznawstwa na terenie Gospodarstwa Doświadczalnego Felin (51°22'N, 22°64'E), należącego do Uniwersytetu Przyrodniczego w Lublinie. W badaniach uwzględniono 2 gatunki pszenicy: Triticum durum linia LGR1359/2 (2009–2012) i ‘SMH87’ (2013–2018) oraz Triticum aestivum ssp. vulgare ‘Parabola’ (lata 2009–2012) i ‘KWS Torridon’ (2013–2018). Celem badań było porównanie plonowania i jakości ziarna pszenicy twardej i zwyczajnej w warunkach klimatycznych Lubelszczyzny. W latach badań poziom plonowania pszenicy twardej w relacji do pszenicy zwyczajnej kształtował się w zakresie od 65,1% w 2014 do 83,8% w 2016 r. Najkorzystniejsze proporcje plonu pszenicy twardej do zwyczajnej odnotowano w latach bardziej suchych (niedobory opadów w maju i czerwcu). Wyższą zawartość białka odnotowano w ziarnie pszenicy twardej. Średnio w omawianym 10-leciu zawartość białka w ziarnie pszenicy twardej wynosiła 15,4%, a w ziarnie pszenicy zwyczajnej – 14,1%.

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Tomina, Elena V., Nikolay A. Kurkin y Sergei A. Mal’tsev. "Микроволновый синтез ортоферрита иттрия и допирование его никелем". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, n.º 2 (15 de junio de 2019): 306–12. http://dx.doi.org/10.17308/kcmf.2019.21/768.

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Установлено активирующее действие микроволнового излучения в процессе синтеза нанопорошков ортоферрита иттрия, допированного никелем, заключающеесяв значительном увеличении скорости процесса, снижении температуры отжига, высокой химической гомогенности синтезированных образцов. Реальная степень допирования согласно результатам локального рентгеноспектрального микроанализа оказалась несколько ниже номинальной, максимальная реальная степень допирования составляет 0.12. Средний размер частиц YFeO3 и NiхY1-хFeO3 находится в диапазоне 200–300 нм. REFERENCES Popkov V. I., Almjasheva O. V. Yttrium orthoferrite YFeO3 nanopowders formation under glycine-nitrate combustion conditions. Russian Journal of Applied Chemistry, 2014, v. 87(2), pp. 167-171. https://doi.org/10.1134/S1070427214020074 Letyuk L. M., Kostishin V. G., Gonchar A. V. Tekhnologiya ferritovykh materialov magnitoelektroniki [Technology of ferrite materials of magnetoelectronics]. Moscow, MISiS Publ., 2005, 352 p. (in Russ.) Petrova E., Kotsikau D., Pankov V. Structural characterization and magnetic properties of sol–gel derived ZnxFe3-xO4 Journal of Magnetism and Magnetic Materials, 2015, v. 378, pp, 429–435. https://doi.org/10.1016/j.jmmm.2014.11.076 Mittova I. Ya., Tomina E. V., Lavrushina S. S. Nanomaterialy: sintez nanokristallicheskikh poroshkov i poluchenie kompaktnykh nanokristallicheskikh materialov: uchebnoe posobie dlya vuzov [Nanomaterials: the synthesis of nanocrystalline powders and the production of compact nanocrystalline materials: a textbook for universities]. Voronezh, LOP VGU Publ., 2007, 35 p. (in Russ.) Brandon D., Kaplan W. Microstructural Characterization of Materials. Chichester: John Wiley & Sons Ltd, 1999, 424 p. Tretyakov Yu. D. Development of inorganic chemistry as a fundamental for the design of new generations of functional materials. Russian Chemical Reviews, 2004, v. 73(9), pp. 831–846. https://doi.org/10.1070/RC2004v073n09ABEH000914 Tomina E. V., Mittova I. Ya., Burtseva N. A., Patent RF, N 2548089, 2015. Kuznetsova V. A., Almjasheva O. V., Gusarov V. V. Infl uence of microwave and ultrasonic treatment on the formation of CoFe2O4 under hydrothermal conditions. Glass Physics and Chemistry, 2009, v. 35(2), pp. 205–209. International Center for Diffraction Data. Shpanchenko R. V., Rozova M. G. Metodicheskaya razrabotka dlya spetspraktikuma k kursu lektsii «Prakticheskie aspekty rentgenovskoi difraktometrii» [Methodical development for the special practical course for lectures “Practical aspects of X-ray diffractometry”]. Moscow, Izd-vo Mosk. un-ta Publ., 1998, 25 p. (in Russ.) Tret’yakov Yu. D. Neorganicheskaya khimiya. Khimiya elementov: uchebnik dlya stud. vuzov, obuch. po napravleniyu 510500 “Khimiya” i spetsial’nosti 011000 “Khimiya” : v 2 t [Inorganic chemistry. Chemistry of elements: a textbook for students. universities enrolled in the direction 510500 “Chemistry” and specialization 011000 “Chemistry”: in 2 volumes]. Moscow, Izd-vo Mosk. un-ta: Akademkniga Publ., 2007, v. 1, 538 p.; v. 2, 670 p. (in Russ.) Tomina E. V., Darinskii B. M., Mittova I. Ya., Churkin V. D., Boikov N. I., Ivanova O. V. Sintez nanokristallov YСоxFe1-xO3 pod vozdeistviem mikrovolnovogo izlucheniya [Synthesis of YСоxFe1-xO3 Nanocrystals Under the Microwave Radiation], Inorganic Materials, v. 55(4), 2019, pp. 421–425. https://doi.org/10.1134/S0002337X19040158 (in Russ.)

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Теrekhоvich, Margarita V., Elena V. Kozina, Irina A. Kokh, Artem N. Narkevich, Olga P. Kolesova, Olga V. Romanovskaya, Natalia K. Kondruseva, Irina V. Usenkova y Iuliia D. Griazeva. "Ophthalmopatology as a cause of primary disability in the adults of Krasnoyarsk region: A 15-year (2007–2021) overview". Medical and Social Expert Evaluation and Rehabilitation 26, n.º 1 (29 de noviembre de 2023): 5–16. http://dx.doi.org/10.17816/mser112023.

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BACKGROUND: Understanding the dynamics and regional features of primary disability formation is crucial for developing organizational and managerial measures to improve the provision of medical care and the system of rehabilitation measures to reduce the level of disability in the population. OBJECTIVE: The study aimed to assess the state and dynamics of primary disability due to ophthalmopathology in the adult population of the Krasnoyarsk Region from 2007 to 2021. MATERIALS AND METHODS: Data sources include forms № 7-SOBES (Information on the medical and social examination of persons aged 18 years and older), statistical collections of the Federal State Budgetary Institution Medical and Social Expertise of the Ministry of Labor of Russia, and reporting documents of the Main Bureau of Medical and Social Expertise in Krasnoyarsk territory from 2007 to 2021. The comparative characteristics of the analyzed data were carried out for three periods: 2007–2011, 2012–2016, and 2017–2021. RESULTS: For 2007–2021, 5,708 people were recognized as disabled for the first time due to the pathology of the eye. The dynamics of primary disability was characterized by unevenness. The values of the intensive indicator of primary disability ranged from 1.7 to 2.6 (mean 1.9) per 10,000 population aged 18 and above. Among those initially recognized as disabled, individuals at retirement age prevailed with an increased instance of 8.5% every subsequent five years. People with disabilities were mainly residents of the cities in the region. Compared with 2007–2011 and 2012–2016 in the last 5 years, the share of IDPs in groups I and II increased (27.1% [524/1,930] and 43.4% [837/1930]), while the proportion people with disabilities of group III decreased (29.5% [569/1930]). The leading cause of disability was glaucoma (32.0% [606/1,891], 30.1% [569/1,887], and 31.1% [599/1,930] in groups I, II, and III, respectively). Second place in the list is occupied by age-related macular degeneration (15.7% [298/1,891], 20.3% [383/1,887], and 27% [522/1,930] in groups I, II, and III, respectively), and the third is myopia (14.1% [268/1,891], 11.2% [211/1,887], and 11.9% [231/1,930] in groups I, II, and III, respectively). CONCLUSION: The dynamics of primary disability due to eye pathology in the adult population of the Krasnoyarsk Territory in 2007–2021 are variable, partly associated with an increase in the number of people with disabilities of retirement age. There was an increase in disability groups during 2017–2021. Therefore, improving the efficiency of preventive medicine and providing the region with medical personnel can help reduce the level of primary disability in the region.

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Edralin, Divina y Ronald Pastrana. "Nexus between Sustainable Business Practices and the Quest for Peace". Bedan Research Journal 5, n.º 1 (30 de abril de 2020): 1–58. http://dx.doi.org/10.58870/berj.v5i1.11.

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We explored the sustainable business practices of selected Philippine corporations that promote the quest for peace. We used three key indicators of sustainable business practices, namely, fostering economic development, espousing corporate citizenship, and respecting the rule of law, as our variables to measure our sustainable business practices construct. On the other hand, we adopted sustainable development and sound business environmental our variables to measure the quest for peace construct. We assumed that sustainable business practices and quest for peace are interlinked and mutually reinforcing. We anchored our study on the Theories of Positive Peace, Sustainable Development, and Humanistic Management. We used the qualitative exploratory research design and the holistic multiple case study research strategy. We used the qualitative exploratory research design and the holistic multiple case study research strategy. We selected through the non-probability purposive sampling technique, the 20 Publicly - Listed Companies in the Philippines. We then, utilized the monomethod as the data collection technique for selecting the Sustainability Reports published in 2018 and uploaded in the websites of the respective corporations. With this deductive approach, we specifically adopted the pattern matching analytical procedure in the process of our content analysis of information from the Sustainability Reports. Results on fostering economic development revealed numerous jobs created, training and development, as well as trade and business development programs and activities executed. Analysis on espousing corporate citizenship disclosed many programs and activities related to encourage the use of voice from the firm, community engagement, and governance implemented. Findings on respecting the rule of law showed also various programs and activities that cover compliance with Philippine laws, international laws, and environmental standards. Findings also indicated that the nexus of sustainable business practices and the quest for peace aims to build companies of enduring greatness by doing good and working toward a sustainable future. In conducting responsible business, they were able to help in attaining positive peace in our coun try, which, in return, is essential for sustainable development, as manifested by their significant contribution in achieving sustainable development/growth, working closely with regulators to achieve shared goals; and protecting the environment and preserving natural resources. We recommend that there should be a coordinated effort of all the stakeholders to ensure that there is an integrated and holistic approach in the sustainability of the business sector to promote positive peace.We also propose to undertake further research on employing quantitative approach by using business, financial, and socio-economic indicators to address the limitations of this study. ReferencesBoulding, E. (2000). Cultures of peace: The hidden side of history. Syracuse University Press. Brauch, H. G., Oswald Spring, U., Grin, J., Scheffran, J. (Ed.). (2016). Handbook on sustainability transition and sustainable peace. Springer.Cortright, D. (2009). Peace: A history of movements and ideas. Cambridge University Press.Creswell, J. (2014). Research design: Qualitative, quantitative, and mixed methods approaches (4th ed.). Sage Publications.Edralin, D. & Pastrana, R. (2019). Sustainability initiatives and practices of selected top universities in Asia, Europe, and USA. Bedan Research Journal. 4, April, 24-45.Elkington, J. (2018, June 25). 25 years ago I coined the phrase “triple bottom line.” Here’s why it’s time to rethink it. Harvard Business Review. https://hbr.org/2018/06/25-years-ago-i-coined-the-phrasetriple-bottom-line-heres-why-im-giving-up-on-it.Ercoşkun, Ö.Y. (2005). Sustainable city plans against development plans. Gazi University Journal of Science, 18(3): 529-544.Ford, J. (2015). Perspectives on the evolving “Business and Peace: Debate”. Academy of Management Perspective,29(4). https://doi.org/10.5465/amp.2015.0142Forrer, J., &Katsos, J. (2015). Business and peace in the buffer condition. Academy of Management Perspectives, 29(4), 438-450. http://dx.doi.org/10.5465/amp.2013.0130Forrer, J., Fort, T., & Gilpin, R. (2012). How business can foster peace.Washington, DC: United States. Institute of Peace. https://www.usip.org/sites/default/files/SR315.pdfFort, T. L. (2007). Business, integrity, and peace: Beyond geopolitical and disciplinary boundaries. Cambridge University Press.Fort, T.L., & Schipani, C.A. (2001, November). The role of the corporation in fostering peace (William Davidson Institute Working Paper No. 422). https://deepblue.lib.umich.edu/bitstream/handle/2027.42/39806/wp422.pdf?sequence=3Fort, T.L., & Schipani, C.A. (2003). Corporate governance and sustainable peace: Intra-organizational dimensions of business behavior and reduced levels of violence. Vanderbilt Journal of Transnational Law, 36(2), 367-386.Fort, T., & Schipani, C. (2004). The ecological challenges of war: The natural environment and disease. In the Role of Business in Fostering Peaceful Societies (pp. 183-222). Cambridge University Press. https://doi.org/10.1017/CBO9780511488634.007Fort, T.L., & Schipani, C.A. (2007). An action plan for the role of business in fostering peace. American Business Law Journal, 44(2), 359-377.Friedman, M. (1970, September). The social responsibility of business is to increase its profits. New York Times Magazine, 33, 122-126.Galtung, J. (1969). Violence, peace, and peace research. Journal of Peace Research. 6(3), 167–191.Galtung, J. (1996). Peace by peaceful means: Peace and conflict, development and civilisation. International Peace Research Insitute.Galtung, J., Jacobsen, C., & Brand-Jacobsen, K. F. (2002). Searching for peace: The road to TRANSCEND. Pluto Press. Global Compact, United Nations. (2006). What is the Global Compact? https://www.unglobal compact.org/aboutInstitute for Economics & Peace (2018, October). Positive peace report 2018: Analysing the factors that sustain peace. http://visionofhumanity.org/reportsKirbassov, G. (n.d.). Peace and sustainable development: A two-way relationship (PositionPaperand Policy Recommendations). https://sustainabledevelopment.un.org/getWSDoc.php?id=3533Leonardsson, H., & Gustav,R. (2015).The ‘local turn’ in peacebuilding: A literature review of effective and emancipatory local peace building. Third World Quarterly, 36(5), 825-839. https://doi.org/10.1080/01436597.2015.1029905Lüdeke-Freund, F. (2010) Towards a conceptual framework of ’business models for sustainability'. In R. Wever, J. Quist, A. Tukker, J. Woudstra, F. Boons, N. Beute (Eds.), Knowledge collaboration & learning for sustainable innovation. Academic Press.Mac Ginty, R. (2012). International peacebuilding and local resistance: Hybrid forms of peace. Palgrave MacMillan. https://doi.org/10.1057/9780230307Martinez-Soliman, M. (2017) Sustainable Development and Sustaining Peace, UNDP, Bureau for Policy and Promotional Support.Mele, D. (2013). Antecedents and current situation of humanistic management. African Journal of Business Ethics, 7(2), 52-61. https:// doi.org/10.4103/1817-7417.123079Oetzel, J., Westermann-Behaylo, M., Koerber, C. et al. (2009). Business and peace: Sketching the terrain. Journal of Business Ethics, 89(4),351-373. https://doi.org/10.1007/s10551-010-0411-7Post, J. E., Preston, L. E., & Sachs, S. (2002). Redefining the corporation: Stakeholder management and organizational wealth. Stanford University Press.Saunders, M., Lewis, P., & Thornhill, A. (2019). Research methods for business students (8th ed.). Pearson Education Limited.Small-Warner, K., Abuzeinab, A., &Taki, A. (2018). A review of sustainable business models and strategic sustainable development. Journal of Business Models, 6(2). 84-89. https://doi.org/10.5278/ojs.jbm.v6i2.2470SSpreitzer, G.(2007). Giving peace a chance: Organizational leadership, empowerment, and peace. Journal of Organizational Behavior, 28(8), 1077-1095. https:// doi.org/10.1002/job.487.UN (2015) Transforming our world: the 2030 agenda for sustainable development. Resolution adopted by the General Assembly on 25 September 2015. https://www.un.org/ga/search/view_doc.aspVirji, H., Sharifi, A., Kaneko, S., &Simangan, D. (2019). 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KHAN, JAHANGIR SARWAR, MOHAMMAD IQBAL y HAMID HASAN. "LAPAROSCOPIC CHOLECYSTECTOMY". Professional Medical Journal 17, n.º 03 (10 de septiembre de 2010): 373–78. http://dx.doi.org/10.29309/tpmj/2010.17.03.2474.

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Objective: To determine the frequency of common bile duct (CBD) injury in laparoscopic cholecystectomy in our settings, in my last 500 cases, after going through the learning curve associated CBD injuries. Design: Descriptive study. Place and Duration of Study: Surgical Unit-I, Rawalpindi General Hospital and the author’s Surgical Clinics from January 2003 to December 2008. Patients and Methods: Five hundred patients undergoing laparoscopic cholecystectomy by the same surgeon were included. The important variables included demographic data, intra operative time and findings, frequency of CBD injury and post operative hospital stay. Results: There were 419(83.8%) females and 81(16.2%) males with mean age 45.04±11.03 years. 294(58.8% )patients had chronic cholecystitis with Cholelithiasis and were admitted through Out Patient Department whereas 206(41.2%) were admitted through Accident and Emergency Department with acutecholecystitis. Abdominal ultrasound showed multiple calculi in 351(70.2%) patients and 149(29.8%) patients had single calculus preoperatively. Empyema was found in 97(19.4%) cases whereas adhesions were present in 182( 36.4%) patients. In our study frequency of CBD injury was 1%. Mean operating time was 35 minutes. 96.8 % of the patients were discharged within 48 hrs of operation. Conclusion: LaparoscopicCholecystectomy in our set up proved to be a safe procedure, having frequency of CBD injury of only 1% and a short hospital stay 493(96.8% )being discharged in less than 2 days.

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SYAFUTRA, RANDI, WAHYU ADI, MUHAMMAD IQBAL y INDRA YUSTIAN. "Short Communication: Dugong dugon Müller, 1776 (Sirenia, Dugongidae) in Bangka Island, Indonesia". Biodiversitas Journal of Biological Diversity 19, n.º 3 (1 de mayo de 2018): 823–30. http://dx.doi.org/10.13057/biodiv/d190310.

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Syafutra R, Adi W, Iqbal M, Yustian I. 2018. Short communication: Dugong dugon Müller, 1776 (Sirenia, Dugongidae) in Bangka Island, Indonesia. Biodiversitas 19: 823-830. Dugong dugon is a marine mammal species classified as Vulnerable. It has distribution in Indonesia, especially in Bangka Island. However, only four records of dugong were reported in Bangka Island in 1976, 2006, and 2007. In addition, there is little published information about local beliefs toward dugong and awareness actions toward dugong conservation in Bangka Island. This research compiled new records of dugong, local beliefs toward dugong, and awareness actions toward dugong conservation in Bangka Island. Sixteen new records of dugong were collected in Bangka Island leading to a total of 18 records for this island. All new records of dugong were obtained entirely from the eastern waters of Bangka Island. The new records also informed that most of the dugongs were found dead and entangled in gill nets. In addition, an interesting local belief caused Kurau Village becomes the most important location for fishermen to sell dead dugongs or dugongs’ meat. Furthermore, three main awareness actions toward dugong had been implemented in Bangka Island in 2017.

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Dong, Mei. "INFLATION AND UNEMPLOYMENT IN COMPETITIVE SEARCH EQUILIBRIUM". Macroeconomic Dynamics 15, S2 (septiembre de 2011): 252–68. http://dx.doi.org/10.1017/s1365100510000799.

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Rocheteau, Rupert, and Wright [Scandinavian Journal of Economics 109 (2007), 837–855] show that the relationship between inflation and unemployment can be positive or negative, depending on the primitives of the model. The key features are indivisible labor, nonseparable preferences, and bargaining. Their results are derived only for a special case of bargaining, take-it-or-leave-it offer by buyers. Instead of bargaining, this paper considers competitive search. I show that the results of Rocheteau et al. can be generalized to an environment where both buyers and sellers have nonseparable preferences. In addition, the relationship between inflation and unemployment is robust to allowing free entry by sellers, which cannot be studied in Rocheteau et al. (2007).

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Lisøy, Carina y Kristin Martinsen. "Måleegenskaper ved den norske versjonen av Beck Anxiety Inventory for ungdom og unge voksne (BAI)". PsykTestBarn 13, n.º 1 (23 de febrero de 2023): 1–16. http://dx.doi.org/10.21337/0080.

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Beskrivelse: Beck Anxiety Inventory (BAI) er et selvrapporteringsinstrument for angstsymptomer utviklet av Beck, Epstein, Brown og Steer i 1988. Norsk versjon ble oversatt av Tone Andersen i 2005, og rettighetshavere er NCS Pearson Inc. BAI inneholder 21 ledd målt på en 4 poengs Likert-skala som danner en sumskår. Målgruppen er ungdommer eller voksne fra alderen 17 år og oppover. Skjemaet tar 5 – 10 minutter å fylle ut for respondenter med normale leseferdigheter. Fortolkning krever kompetanse tilsvarende klinisk psykolog eller lege. Litteratursøk: Vi søkte etter skandinaviske publikasjoner som rapporterte måleegenskaper eller normdata for BAI i utvalg av ungdom eller unge voksne med gjennomsnittsalder under 26 år. Av 838 referanser, ble 13 inkluderte. Bare én av publikasjonene (en masteroppgave) var en psykometrisk studie. Psykometri: En studie fant at deltakere med angstdiagnoser skåret høyere på BAI enn deltakere med depresjon. Kriterievaliditet for BAI ble undersøkt i en publikasjon, som rapporterte at BAI hadde lav diagnostisk nøyaktighet. Konvergerende validitet, vurdert ved korrelasjonskoeffisienter mellom BAI og andre angstmål, varierte fra «utilstrekkelig» til «utmerket». Faktorstruktur ble undersøkt i en publikasjon, som ikke var fagfellevurdert, og det er stor usikkerhet knyttet til faktorstrukturen til BAI i skandinaviske utvalg, og også internasjonalt. Indre konsistens var rapportert i 11 publikasjoner, og alle fant høy indre konsistens for samlede BAI skårer. God til utmerket test-retest reliabilitet ble funnet i tre publikasjoner. BAI normdata, indikasjoner på endringssensitivitet eller måleinstrumentets invarians ble ikke funnet rapportert i de inkluderte publikasjonene. Konklusjon: Måleegenskapene til den skandinaviske versjonen av BAI er i liten grad dokumentert i utvalg av ungdom eller unge voksne i Skandinavia. Vi anbefaler å benytte måleinstrumentet med forsiktighet blant ungdom og unge voksne frem til gode måleegenskaper av skandinaviske versjoner av BAI er dokumentert.

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Lessmann, Christian. "Regional Inequality and Internal Conflict". German Economic Review 17, n.º 2 (1 de mayo de 2016): 157–91. http://dx.doi.org/10.1111/geer.12073.

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Abstract This paper studies the influence of regional inequality within countries on internal conflicts. Regional inequalities are measured by the population-weighted coefficient of variation of regional GDP per capita. As the main innovation, I use a panel dataset of country-level regional inequalities, which covers 56 countries (835 subnational regions) between 1980 and 2009. I also consider a broader cross section dataset for the year 2005, which covers 110 countries (1569 subnational regions). Conflict is measured by the incidence of civil war (UCDP/PRIO data) and a risk measure of internal conflict (war, terrorism and riots) provided by the PRS Group’s International Country Risk Guide. Logit estimations are employed as well as OLS fixed effects panel regressions. I find that regional inequalities increase the risk of internal conflict.

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Aragon-Ching, Jeanny B., Hongkun Wang y Donald L. Trump. "Survival outcomes and patterns of utilization of cytoreductive nephrectomy in the tyrosine kinase inhibitors (TKI)-era in metastatic clear cell renal cell carcinoma (ccRCC) and non-clear cell renal cell carcinoma (nccRCC): Analyses from the National Cancer Database (NCDB)." Journal of Clinical Oncology 35, n.º 15_suppl (20 de mayo de 2017): e16068-e16068. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e16068.

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e16068 Background: Use of TKIs is standard of care for metastatic ccRCC and cytoreductive nephrectomy has improved survival even in metastatic ccRCC. The use of cytoreductive nephrectomy in the TKI era post-2005 for nccRCC histologies is unknown. We sought to determine trends and explore differences in characteristics of ccRCC and nccRCC, use of cytoreductive nephrectomy and survival outcomes for varying stages. Methods: Using a de-identified dataset acquired from the NCDB from 2004 to 2014, extraction of demographic information on patients divided into ccRCC versus nccRCC. Descriptive statistics was used for summarizing patients’ characteristics. Chi-Square test was used for comparing categorical variables. Two-sample t-test was used for comparing continuous variables. Kaplan-Meier method was used to analyze patients’ survival data. Results: 302,339 (82%) ccRCC and 66,530 (18%) nccRCC patients were identified. nccRCC included papillary (n = 42,251), sarcomatoid (n = 5769), chromophobe (n = 17,671) and collecting duct (n = 839). The median age for both groups was 63 years, more common in males (ccRCC = 61%; nccRCC = 69%), and mostly Caucasians (ccRCC = 86%; nccRCC = 75%). Most patients were treated in comprehensive community and academic research programs (ccRCC = 81%; nccRCC = 83%). Majority of patients were diagnosed with AJCC Stage I (ccRCC = 57%, nccRCC = 62%). Stage IV was diagnosed in 14% of ccRCC and 9% of nccRCC. The utilization of nephrectomy declined for ccRCC at 36% in the year 2014 compared to 44% in 2005, whereas it declined more for nccRCC with 47% in 2014 compared to 70% in 2005. The median survival time for Stage I was comparable in both groups (ccRCC = 140 mos, 95% CI 138.8 – 142.16; nccRCC = 140 mos, 95% CI 138 – unestimable). However, median survival was worse for stage IV in nccRCC (ccRCC = 9 mos; 95% CI 8.8 – 9.17; nccRCC = 7.43 mos; 95% CI 7.16 – 7.79). Conclusions: In stage IV patients with nccRCC, cytoreductive nephrectomy is used less often and overall survival appears inferior compared to ccRCC.

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Tjan-Heijnen, V. C., M. J. Pepels, M. de Boer, G. F. Borm, J. A. van Dijck, C. H. van Deurzen, E. M. Adang, M. B. Menke-Pluymers, P. J. van Diest y P. Bult. "Impact of omission of completion axillary lymph node dissection (cALND) or axillary radiotherapy (ax RT) in breast cancer patients with micrometastases (pN1mi) or isolated tumor cells (pN0[i+]) in the sentinel lymph node (SN): Results from the MIRROR study". Journal of Clinical Oncology 27, n.º 18_suppl (20 de junio de 2009): CRA506. http://dx.doi.org/10.1200/jco.2009.27.18_suppl.cra506.

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CRA506 Background: The Dutch MIRROR study is the largest cohort study on pN1mi and pN0(i+) in the SN era with long-term follow-up, central pathology review (6th AJCC-classification), and separate analyses on the use of adjuvant systemic therapy (AST). In patients not receiving AST, pN1mi and pN0(i+) as final N-stage were shown to be independent prognosticators for disease-free survival (SABCS 2008, #23, oral). As a substantial number of patients in the MIRROR study did not undergo cALND or ax RT, we questioned whether this policy was safe in patients with pN1mi(sn) or pN0(i+)(sn). Methods: Patients operated for breast cancer in all Dutch hospitals in the years 1998–2005, having favorable primary tumor characteristics, and having undergone an SN biopsy without macrometastases as final N-stage were included. For this present research question, patients were categorized by their SN-stage. Median follow-up was 4.7 years. The Kaplan-Meier method was used to estimate 5-year axillary recurrence (AR) rates, and Cox regression was used to estimate the hazard ratios (HR). In the analyses, the effect of AST was taken into account. Results: In total, 835 patients with pN0(i-)(sn), 799 patients with pN0(i+)(sn), and 958 patients with pN1mi(sn) were included. AR rates, and HRs on AR are displayed below. Conclusions: Omission of cALND or ax RT in patients with pN1mi(sn) resulted in a significantly higher 5-year AR rate, even after correction for AST, and other patient and tumor characteristics. This indicates that patients with pN1mi(sn) should undergo cALND or ax RT to prevent AR. Support: The Netherlands Organization for Health Research and Development (ZonMw) and the Dutch Breast Cancer Trialists’ Group (BOOG). [Table: see text] No significant financial relationships to disclose.

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Mondal, I., V. K. Srivastava, P. S. Roy y G. Talukdar. "Using logit model to identify the drivers of landuse landcover change in the Lower Gangetic Basin, India". ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-8 (28 de noviembre de 2014): 853–59. http://dx.doi.org/10.5194/isprsarchives-xl-8-853-2014.

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The Lower Gangetic Basin is one of the most highly populated areas of India, covering an area of 286,899 km2 with a population density of 720 persons per km2. 64 % of the area is covered under agriculture which is supported by the highly fertile alluvial soil. Landuse and landcover (LULC) changes due to an ever increasing human population, natural disasters induced by climate change can alter agricultural productivity which in turn can affect the food security of the region. The current study found out the change in LULC over a span of 20 years (1985–2005), and identified the factors driving this change. LULC data was generated from geo-corrected satellite data of LANDSAT-MSS, IRS LISS-I and IRS LISS-III for pre monsoon and post monsoon seasons for the years 1985–86, 1994–95 and 2004–05 respectively, using onscreen visual interpretation at 1 : 250,000 scale. We used cross-tabulation matrix to investigate landuse and landcover transformation. The most significant transformation has been to built-up category, contributed by agricultural land (515 km2) and scrubland (53 km2). The other notable transformations are from agriculture to plantation (247 km2), fallow to scrubland (838 km2) and from water body to scrubland (407 km2). We generated change no-change matrix and analyzed it using logistic regression to investigate the drivers of LULC change. We identified availability of water for irrigation, literacy, sexratio and the availability of different sources of livelihoods, as the major drivers of LULC change in the Lower Gangetic Basin.

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Kim, Kwangsoon, Jin Kyong Kim, Cho Rok Lee, Sang-Wook Kang, Jandee Lee, Jong Ju Jeong, Kee-Hyun Nam y Woong Youn Chung. "Comparison of long-term prognosis for differentiated thyroid cancer according to the 7th and 8th editions of the AJCC/UICC TNM staging system". Therapeutic Advances in Endocrinology and Metabolism 11 (enero de 2020): 204201882092101. http://dx.doi.org/10.1177/2042018820921019.

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Background: The 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumor-node-metastasis (TNM) staging system was released with major revisions. The purpose of this retrospective study was to investigate differences between the 7th and 8th editions of the AJCC/UICC TNM staging system and to compare the predictability of prognosis between the two staging systems with patients who underwent thyroidectomy for differentiated thyroid cancer (DTC) at a single institution. Methods: A total of 3238 patients underwent thyroid operation from January 2002 to December 2006 at Yonsei University Hospital (Seoul, Korea), of which 2294 with complete clinical data and sustained follow up were enrolled. Clinicopathologic features and TNM staging by applying the 7th and 8th editions of the AJCC/UICC were analyzed retrospectively by the complete review of medical charts and pathology reports of patients. Mean follow-up duration was 132.9 ± 27.9 months. Results: A significant number of T3 patients were downstaged to T1 (838, 36.5%) and T2 (122, 5.3%). After applying the 8th edition of the AJCC/UICC TNM staging system, the number of stage I patients increased significantly from 1434 (62.5%) to 2058 (89.7%), whereas numbers of stage III and IV patients decreased significantly from 644 (28.1%) to 33 (1.4%) and from 199 (8.7%) to 17 (0.7%), respectively. According to Kaplan–Meier survival analyses and values of the Harrell’s c-index and integrated area under the curve (iAUC), the 8th edition has significantly better predictive performance for disease-free survival (DFS) and disease-specific survival (DSS) than the 7th edition. Conclusions: A significant population was downstaged after applying the 8th edition of the AJCC/UICC TNM staging system, and the 8th edition provided significantly better accuracy in predicting DFS and DSS in patients with DTC.

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Jaja, Tonye Clinton. "Sharia Implementation in Northern Nigeria, 1999–2006: A Sourcebook, compiled and edited by Philip Ostien, Volumes I–V [Ibadan, Nigeria: Spectrum Books Limited, 2007], ISBN: 978-978-029-837-1." African Journal of International and Comparative Law 18, n.º 1 (marzo de 2010): 104–10. http://dx.doi.org/10.3366/e095488900900053x.

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Wendt, Amanda S., Maria E. Jefferds, Cria G. Perrine, Patricia Halleslevens y Kevin M. Sullivan. "Obese women less likely to have low serum ferritin, Nicaragua". Public Health Nutrition 18, n.º 4 (22 de mayo de 2014): 736–41. http://dx.doi.org/10.1017/s1368980014000755.

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AbstractObjectiveTo examine the association between overweight and obesity and serum ferritin among women of reproductive age (15–49 years) in Nicaragua, considering the effect of α1-acid glycoprotein (AGP), a marker of inflammation.DesignWe analysed data from the 2004–05 Nicaraguan Integrated Surveillance System for Nutrition Interventions. Three logistic regression models were analysed with low serum ferritin (<15 μg/l) as the dependent variable: (i) overweight or obese status and covariates; (ii) model 1 plus AGP; and (iii) model 1 restricted to only women with normal AGP levels (≤1·0 g/l).SettingNicaragua.SubjectsIncluded in this analysis were 832 non-pregnant mother/caregivers (15–49 years) surveyed in 2004–2005.ResultsIn the sample, prevalence of overweight and obesity was 31·8 % and 19·2 %, respectively, and 27·6 % had low serum ferritin. In model 1, the adjusted OR of low serum ferritin was 0·74 (95 % CI 0·52, 1·05) for overweight women and 0·42 (95 % CI 0·26, 0·65) for obese women. In model 2, AGP was significantly independently associated with low serum ferritin (adjusted OR=0·56, 95 % CI 0·34, 0·92) while the adjusted OR for overweight and obesity were largely unchanged. Excluding women with elevated AGP did not appreciably affect the relationship between overweight or obesity and low serum ferritin (model 3).ConclusionsOverall, in this population of reproductive-age women, obese women were less likely to have low serum ferritin levels, and this was independent of inflammation as measured by AGP.

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Caballero, Juan Luis. "Joseph LORTZ, Historia de la Iglesia en la perspectiva de la historia del pensamiento. Tomo I: Antigüedad y Edad Media. Tomo II: Edad Moderna y Contemporánea, Madrid: Ediciones Cristiandad, 2003 (I) y 2008 (II), 766 pp. (I) y 839 pp. (II), 15 x 20". Scripta Theologica 42, n.º 2 (4 de febrero de 2016): 513. http://dx.doi.org/10.15581/006.42.3741.

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Earl, H. M., A. Vallier, L. Hiller, N. Fenwick, M. Iddawela, L. Hughes-Davies, E. Provenzano, K. McAdam, T. Hickish y C. Caldas. "Neo-tAnGo: A neoadjuvant randomized phase III trial of epirubicin/cyclophosphamide and paclitaxel ± gemcitabine in the treatment of women with high-risk early breast cancer (EBC): First report of the primary endpoint, pathological complete response (pCR)". Journal of Clinical Oncology 27, n.º 15_suppl (20 de mayo de 2009): 522. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.522.

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522 Background: Neo-tAnGo used a 2-by-2 factorial design, addressing: (i) gemcitabine (G) in a sequential neoadjuvant chemotherapy (CT) regimen of epirubicin/cyclophosphamide (EC) and paclitaxel (T); and (ii) the sequencing of these treatment components (EC then T ± G versus T ± G then EC). Methods: Patients (Pts) with early breast cancer (T2 tumours or above) were randomised to EC then T, T then EC, EC then TG or TG then EC. All components were given x 4 cycles. (E= 90 mg/m2 day (d)1 every (q) 21d; C = 600 mg/m2 d1 q21d; T = 175 mg/m2 d1 q14d; G = 2,000 mg/m2 d1 q14d.) The primary endpoint was pCR, defined as absence of invasive disease in the breast and axillary lymph nodes. 800 pts were required to detect 10% differences in the primary endpoint pCR rates, at the 5% (2-sided) significance level with 85% power. Stratification was by age, inflammatory/locally advanced disease, tumour size, clinical involvement of axillary nodes and oestrogen receptor (ER) status. Results: Between January 2005 and September 2007, 831 pts were randomised by 88 consultants from 57 UK centres. Characteristics were balanced across groups: 63% <50 years old, 25% had inflammatory and/or locally advanced disease, 79% of tumours <50 mm, 50% node positive and 34% ER negative. Two-reader review of 813 (98%) eligible pts'. pathology reports, blinded to treatment arm, were carried out. pCR rates were 17% (95% CI 14–21) for EC&T pts and 17% (95% CI 14–21) for EC&TG pts (p = 0.98). However the sequence T±G then EC, showed pCR of 20% (95% CI 16–24) compared with 15% (95% CI 11–18) for EC then T±G pts (p = 0.03). Adjustment by stratification did not alter results. Conclusions: The Neo-tAnGo results confirm those of the adjuvant tAnGo trial in terms of gemcitabine effect (ASCO 2008). The sequence of T±G-first has demonstrated a significant advantage in pCR compared with the more conventional anthracycline-first sequencing. [Table: see text]

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García, Susan Paun de. "John Beusterien An Eye on Race. Perspectives from Theater in Imperial Spain. Lewisburg: Bucknell UP, 2006. 228pp. ISBN: 0-8387-5614-X." Cervantes 28, n.º 1 (marzo de 2008): 202–5. http://dx.doi.org/10.3138/cervantes.28.1.202.

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González Fernández, Rafael y Miguel Pablo Sancho Gómez. "La institución del domicilium (en Derecho romano) y su expresión en la epigrafía latina". Vínculos de Historia Revista del Departamento de Historia de la Universidad de Castilla-La Mancha, n.º 11 (22 de junio de 2022): 296–310. http://dx.doi.org/10.18239/vdh_2022.11.13.

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La institución romana del domicilium convierte al sujeto en residente. Suele designar el lugar de residencia prolongada del incola o habitante que ha emigrado a una comunidad, por contraposición al municeps; por lo tanto, es un vínculo jurídico entre la ciudad y la persona que ha emigrado a ella. Frente a la expresión de la origo en los textos epigráficos, que es muy abundante, la manifestación del domicilo solo se hace de forma excepcional, en atención al escaso número de referencias conservadas, y su enunciación es muy similar a la que marca el origen. Palabras clave: domicilium, origo, ciudadano, epigrafía, latina.Topónimos: Imperio Romano.Periodo: Principado (27 a. C. – 284 d. C.) ABSTRACTThe Roman institution of the domicilium turns the subject into a resident. It usually designates the place of prolonged residence of the incola or inhabitant who has emigrated to a community, as opposed to the municeps. Therefore, it is a legal link between the city and the person who emigrates there. As opposed to the expression of the origo in epigraphic texts, which is very common, the manifestation of the domicile occurs only exceptionally, in view of the scant number of surviving references, and its enunciation is very similar to that which indicates provenance. Keywords: domicilium, origo, citizen, epigraphy, Latin.Place names: Roman EmpirePeriod: Principate (27 BC - 284 AD) REFERENCIASAncelle, A. (1875), Du Domicile, Paris, these pour le doctorat, Faculte de droit de Paris.Andreu, J., (2008), “Sentimiento y orgullo cívico en Hispania: en torno a las menciones de origo en la Hispania Citerior”, Gerión, 26(1), pp. 349-378.Ayiter, K. (1962),“Einige Bemerkungen zum Domicilium des Filius Familias im römischen Recht“, en Studi in onore di Emilio Betti, vol. II, Milano, pp. 71-84.Baccari, M. P. (1996), Cittadini, popoli e comunione nella legislazione dei secoli IV-VI, Torino, G. Giappichelli.Baudry, F. (1892), s.v. “domicilium”, en Dictionnaire des Antiquités Grecques et Romaines Daremberg-Saglio, II.1, Paris, Hachette.Berger, A, (1916), s.v. “incola”, en Pauly-Wissowa Realencyclopädie der classischen Altertumswissenschaft, IX.2, Stuttgart, J. B. Metzler Verlag.Bianchi, L. (2019), “Celebrazioni monumentali delle guerre daciche di Traiano sui luoghi degliavvenimenti”, en A. M. Liberati, Da Roma all’Oriente. Riflessioni sulle campagne traianee. Atti della Giornata di studi Istituto Nazionale di Studi Romani, 11 ottobre 2017. Città di Castello-Italia: LuoghInteriori, 193-241.Bonjour, M. (1975), Terre natale. Études sur une composante affective du patriotisme romain, Paris, Les Belles Lettres.Brugi, B. (1926), Istituzioni di Diritto Romano (diritto privato giustinianeo). Torino, Utet.Bruguière, M. B. (1979), “Le domicile dans les droits antiques”, en Mélanges dédiés à Gabriel Marty, Tolouse, Université des sciences sociales, 199-219.Burdese, A. (1964), s.v. “Domicilio (diritto romano)”, voce dell'Enciclopedia del Diritto, XIII, Milano, Giuffrè editore, pp. 837-838.Cagnat, R. (1898), Cours d’epigraphie latine, Paris, A. Fontemoing.Calzada, M. A. (2010), “Origo, incolae, municipes y civitas Romana a la luz de la «Lex Irnitana»”, Anuario de historia del derecho español, 80, pp. 673-688.Chavanes, H., (1863), Du Domicile, Paris, Thèse de Doctorat, Faculté de Droit de Paris, 17 Août 1863.Cichorius, C. (1904), Die römischen denkmäler in der Dobrudscha. Ein erklärungsversuch, Berlin, Weidmann Verlag.Colin, J. (1956), “Le Préfet du Prétoire Cornelius Fuscus: un enfant de Pompei”, Latomus, 15-1, pp. 57-82.Cuena, J. (2008), “Nuevos significados de origo en las fuentes legislativas postclásicas”, Revista General de Derecho romano, 10, pp. 1-27.De Martino, F. (1973), Storia della costituzione romana, III, Napoli, Casa Editrice Eugenio Jovene.De Ruggiero, E. (1921), La patria nel diritto pubblico romano, Roma, Maglione Strini.De Savigny, F. (1924), Sistema de Derecho romano actual, (traducción española de J. Mesía y M. Poley), Madrid, Centro Editorial de Góngora.Dessau, H. (1914-1916), Inscriptiones Latinae Selectae: pars III. Indices, Berlín, apud Weidmannos.D'Ors, A. (1951), Epigrafía de la España romana, Madrid, Instituto Nacional de Estudios Jurídicos.Encarnação, J. (2000), “L’Africa et la Lusitania: trois notes épigraphiques”, en M. Khanoussi, P. Ruggeri y C. Vismara, L’Africa romana. Geografi, viaggiatori, militari nel Maghreb: alle origini dell’archeologia nel Nord Africa. Atti del XIII convegno di studio Djerba, 10–13 dicembre 1998, Roma, Carocci, Vol. II, pp. 1291-1298.Forcellini, A. A. (1965), Lexicon Totius Latinitatis, II, Patavaii, 1940 (2ª reimpresión anastática de 1965), Patavii [Padoue], Gregoriana edente; Bononia [Bologne], A. Forni. s. v. “domicilium”, pp. 191 ss., y s.v. “domus”, pp. 194 ss.Humbert, G. (1900), s.v. “incola”, en Dictionnaire des Antiquités Grecques et Romaines Daremberg-Saglio, III, Paris, Hachette, pp. 457-458.Gagliardi, L. (2006), Mobilità e integrazione delle persone nei centri cittadini romani. Aspetti giuridici. I. La classificazione degli incolae, Milano, A. Giuffrè.García, E. (1991), El ius latii y la municipalización de Hispania: aspectos constitucionales, Tesis Doctoral, Universidad Complutense, Madrid.Gaspard, A. (1851), Recherches sur l'incolat, le droit de bourgeoisie et le domicile, Paris, Faculté de droit de Paris.González, R. (2011), “El término origo en la epigrafía latina”, Zephyrus, 68, pp. 229-237.González, R., y Molina, J. A. (2011), “Precisiones a las menciones de origo con la fórmula domo + topónimo/gentilicio en la epigrafía romana de Hispania”, Emerita, 79, pp. 1-29.González M. C. y Ramírez, M. (2007), “Observaciones sobre la mención de la origo ‘intra ciuitatem’ en la epigrafía funeraria de Hispania”, en M. 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Hahn, Jinyong. "THE INFORMATION BOUND OF A DYNAMIC PANEL LOGIT MODEL WITH FIXED EFFECTS". Econometric Theory 17, n.º 5 (25 de septiembre de 2001): 913–32. http://dx.doi.org/10.1017/s0266466601175031.

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In this paper, I calculate the semiparametric information bound in two dynamic panel data logit models with individual specific effects. In such a model without any other regressors, it is well known that the conditional maximum likelihood estimator yields a √n-consistent estimator. In the case where the model includes strictly exogenous continuous regressors, Honoré and Kyriazidou (2000, Econometrica 68, 839–874) suggest a consistent estimator whose rate of convergence is slower than √n. Information bounds calculated in this paper suggest that the conditional maximum likelihood estimator is not efficient for models without any other regressor and that √n-consistent estimation is infeasible in more general models.

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