Literatura académica sobre el tema "Α/β Peptide"
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Artículos de revistas sobre el tema "Α/β Peptide"
Checco, James W., Dale F. Kreitler, Nicole C. Thomas, David G. Belair, Nicholas J. Rettko, William L. Murphy, Katrina T. Forest y Samuel H. Gellman. "Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold". Proceedings of the National Academy of Sciences 112, n.º 15 (30 de marzo de 2015): 4552–57. http://dx.doi.org/10.1073/pnas.1420380112.
Texto completoOppegård, Camilla, Gunnar Fimland, Lisbeth Thorbæk y Jon Nissen-Meyer. "Analysis of the Two-Peptide Bacteriocins Lactococcin G and Enterocin 1071 by Site-Directed Mutagenesis". Applied and Environmental Microbiology 73, n.º 9 (2 de marzo de 2007): 2931–38. http://dx.doi.org/10.1128/aem.02718-06.
Texto completoFox, Robert I. y Ho-Il Kang. "Mechanism of Action of Antimalarial Drugs: Inhibition of Antigen Processing and Presentation". Lupus 2, n.º 1_suppl (febrero de 1993): 9–12. http://dx.doi.org/10.1177/0961203393002001031.
Texto completoMaruthainar, K., Y. Peng-Loh y D. G. Smyth. "The processing of β-endorphin and α-melanotrophin in the pars intermedia of Xenopus laevis is influenced by background adaptation". Journal of Endocrinology 135, n.º 3 (diciembre de 1992): 469–78. http://dx.doi.org/10.1677/joe.0.1350469.
Texto completoClark, David C., Linda J. Smith y Lesley C. Chaplin. "The Effect of Dephosphorylation on the Conformation of Peptides from β-Casein". Collection of Czechoslovak Chemical Communications 57, n.º 2 (1992): 425–28. http://dx.doi.org/10.1135/cccc19920425.
Texto completoOlsen, Christian A., Gitte Bonke, Line Vedel, Anne Adsersen, Matthias Witt, Henrik Franzyk y Jerzy W. Jaroszewski. "α-Peptide/β-Peptoid Chimeras". Organic Letters 9, n.º 8 (abril de 2007): 1549–52. http://dx.doi.org/10.1021/ol070316c.
Texto completoYin, Hang, Hua Zhu, Gaston Vilaire, Wei Li, Rustem I. Litvinov, William F. DeGrado y Joel S. Bennett. "Activation of Platelet α Iibβ 3 by Exogenous Peptides Corresponding to the Transmembrane Domains of α Iib and β 3." Blood 106, n.º 11 (16 de noviembre de 2005): 384. http://dx.doi.org/10.1182/blood.v106.11.384.384.
Texto completoBerlicki, Łukasz, Ludwig Pilsl, Edit Wéber, István M. Mándity, Chiara Cabrele, Tamás A. Martinek, Ferenc Fülöp y Oliver Reiser. "Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid". Angewandte Chemie International Edition 51, n.º 9 (26 de enero de 2012): 2208–12. http://dx.doi.org/10.1002/anie.201107702.
Texto completoJin, Yi, Janet Hammer, Michelle Pate, Yu Zhang, Fang Zhu, Erik Zmuda y Jack Blazyk. "Antimicrobial Activities and Structures of Two Linear Cationic Peptide Families with Various Amphipathic β-Sheet and α-Helical Potentials". Antimicrobial Agents and Chemotherapy 49, n.º 12 (diciembre de 2005): 4957–64. http://dx.doi.org/10.1128/aac.49.12.4957-4964.2005.
Texto completoLegrand, Baptiste y Ludovic T. Maillard. "α,β‐Unsaturated γ‐Peptide Foldamers". ChemPlusChem 86, n.º 4 (abril de 2021): 629–45. http://dx.doi.org/10.1002/cplu.202100045.
Texto completoTesis sobre el tema "Α/β Peptide"
Das, Chittaranjan. "Designed β-Hairpin, β-Sheet And Mixed α-β Structures In Synthetic Peptides". Thesis, Indian Institute of Science, 2000. http://hdl.handle.net/2005/263.
Texto completoKil, Hyun Joo. "Design & Synthesis of Peptidomimetics Adopting Secondary Structures for Inhibition of p53/MDM2 Protein-protein Interaction and Multiple Myeloma Cell Adhesion". Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5051.
Texto completoLopez-Perez, Elvira. "La voie α-sécrétase de maturation de la protéine précurseur du peptide β-amyloi͏̈de dans la maladie d'Alzheimer : activités protéolytiques et régulation". Nice, 2000. http://www.theses.fr/2000NICE5459.
Texto completoSaraiva, rosa Nathalie. "Synthèse diastéréosélective de molécules azotées α-trifluorométhylées - Élaboration et études conformationnelles de petits peptides incorporant des acides β-aminés trifluorométhylés". Thesis, Reims, 2017. http://www.theses.fr/2017REIMS013.
Texto completoChiral N-tert-butansulfinamides, developped by Ellman 20 years ago, have been increasingly applied for the preparation of chiral functionnalized amines, because of the affordability of both enantiomers and of their mild conditions of cleavage. However, the use of theses auxiliaries for the synthesis of quaternary trifluoromethyl derivatives remains quite limited, the corresponding trifluoromethyl ketoimines being highly unstable.Chiral N-tert-butanesulfinyl alkyl(aryl) trifluoromethyl hemiaminal ethers have been developped to be used as bench-stable surrogates of these ketoimines : once under reaction conditions, they afford the corresponding ketoimine in situ, which can be subject to a nucleophilic addition.In this manuscript, different reactions led on these hemiaminal ethers are described, affording valuable and optically pure trifluoromethylated quaternary building-blocks : on the one hand, homoallylic amines, obtained by the addition of allylalane species, and which can afford, after a few steps, teh corresponding trifluoromethyl azetidines, and on the other hand, chiral trifluoromethyl β3,3-amino acids, afforded by a highly diastereoselective Reformatsky reaction.These β 3,3-amino acids have been then involved in solution-phase peptide couplings in order to synthetise a wide range of α/β- and β-di- and tripeptides, whose conformation have been the object of preliminary studies in the solid state and/or in solution.Key-words : Ellman auxiliary, Nucleophilic addition, Solution-phase peptide coupling, α-trifluoromethylated nitrogen derivative, Hemiaminal ether, asymmetric synthesis
Attal, Sandra. "Utilisation des enzymes en chimie organique : application à la synthèse d'esters de dipeptides par la papai͏̈ne et de galactosyl-sérines par les α-et β-galactosidases". Paris 5, 1992. http://www.theses.fr/1992PA05P614.
Texto completoCollet, Magalie. "Peptidonucléoside polyoxine J, inhibiteur de la chitine synthase : approches vers la synthèse du nucléoside C2' - désoxy -C2' fluoré, et synthèse de l'acide 5-O-carbamoyle polyoxamique". Toulouse 3, 2004. http://www.theses.fr/2004TOU30198.
Texto completoPolyoxins, which form an important class of peptidyl nucleosidic antibiotics that selectively and competitively inhibit chitin synthase, are very active components in vitro, but weakly bioavailable in vivo. The subject of this thesis has been to found new synthetic methods to access to C2'-fluoro-C2'-deoxy analogues of thymine polyoxine C, nucleosidic part of polyoxine J (the more active one), and to obtain, by an original way, the non natural peptidic moiety of polyoxine J, which is the 5-O-carbamoyl polyoxamic acid. After a presentation of the biological target and the interest of the introduction of a fluorine atom, this work is divided into two parts. Fisrt, two approaches of the fluorinated nucleosodic part using 2-deoxy-2-fluorobutyrolactones as intermediates, and then, an optimization of the synthesis of the peptidic part using the formation of an oxazolidonone intermediate
Norgren, Anna S. "Conformational Stability!? : Synthesis and Conformational Studies of Unnatural Backbone Modified Peptides". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7420.
Texto completoPatino, Nadia. "Peptides fluorés : intérêt et synthèse de peptides incorporant dans leur structure un acide α-aminé β-fluoré". Nice, 1989. http://www.theses.fr/1989NICE4274.
Texto completoWillems, Hendrika Maria Gerarda. "The design and synthesis of non-peptidic α-helix and β-turn mimetics". Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627463.
Texto completoClaudel, Stéphanie. "Les peptides Vinylogues : des nouveaux outils pour la préparation d'analogues contraints de la substance P, de γ-aminoacides α, β-hydroxylés et de dihydroxylactames". Nancy 1, 2004. http://www.theses.fr/2004NAN10039.
Texto completoThis work concerns conception and synthesis of modified peptides and is divided in two parts. Firstly, it's the insertion of vinylogous amino acids with cis and trans conformation in neuropeptide of eleven amino acids which is substance P in order to understand its interaction with NK-1 receptor. A second study has been oriented on the preparation of g-amino peptides by hydrogenation of previous vinylogous amino acids. This structural modification has given a new SP's analog which has been tested. The second part is the methodology of synthesis using vinylogous peptides and is divided in three chapters. First one presents dihydroxylation's results of these residues with an asymmetric induction using chiral catalyst to obtain dihydroxylated g-amino acids. Second one is an application of these studies with a total synthesis of natural product extracted from nyctinastic plant. And the last one deals with preparation of dihydroxylated lactams leading to the synthesis of new azasugars
Capítulos de libros sobre el tema "Α/β Peptide"
Hartsock, Wendy J. y Robert S. Hodges. "Rational Design of Amphipathic α-Helical and Cyclic β-Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential". En Peptide Drug Discovery and Development, 91–117. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527636730.ch4.
Texto completoSingh, T. P., B. Padmanabhan, P. Narula, A. K. Saxena, C. Betzel, P. Sharma y S. Dey. "Design of Specific Peptide Structures and Subtilisin Enzyme Inhibitors Using α, β-Dehydro-Residues". En Advances in Experimental Medicine and Biology, 11–20. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0319-0_3.
Texto completoBlaskovich, M. A. y G. A. Lajoie. "Stereoselective synthesis of β-substituted-β-hydroxy α-amino acids and β,γ-unsaturated α-amino acids from serine and threonine". En Peptides, 167–69. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_52.
Texto completoBoitel, Brigitte, Myriam Ermonval, Ulrich Blank y Oreste Acuto. "T-Cell Antigen and MHC Recognition: Molecular Analysis of Human α/β TCR Specific for a Tetanus Toxin-Derived Peptide". En T Lymphocytes, 1–16. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3054-1_1.
Texto completoLong, Yi-cheng, Fei-ning Ye, Yun-hua Ye y Qi-yi Xing. "Studies on the interconversions of the neuroexcitotoxin β-N-oxalo-L-α, β-diaminopropionic acid from Panax species and its isomer α-N-oxalo-L-α, β-diaminopropionic acid". En Peptides, 189–90. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_55.
Texto completoBlaskovich, M. A., A. W. Wong y G. A. Lajoie. "Synthesis of optically enriched β,γ-unsaturated α-amino acids". En Peptides 1994, 205–6. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_85.
Texto completoTung, Roger D., Chong-Qing Sun, Don Deyo y Daniel H. Rich. "Asymmetric syntheses of β-OH and β-OH, γ-alkyl α-amino acids: Analogs of the unusual cyclosporin amino acid MeBmt". En Peptides, 149–51. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_43.
Texto completoDiaz-Diaz, M., S. Mzengeza, O. P. Ward, J. F. Honek y G. Lajoie. "Asymmetric synthesis of β-hydroxy L-α-amino acids using aldolase from Pseudomonas sp". En Peptides, 517–18. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_198.
Texto completoViso, Alma y Roberto Fernández de la Pradilla. "Synthetic Approaches to α,β-Diamino Acids". En Amino Acids, Peptides and Proteins in Organic Chemistry, 411–40. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527631766.ch9.
Texto completoIbuka, T., K. Nakai, H. Habashita, Y. Hotta, A. Otaka, N. Fujii, N. Mimura, Y. Miwa, T. Taga y Y. Yamamoto. "A new route to stereochemically pure (E)-alkene dipeptide isosteres from β-aziridino-α,β-enoates via organocopper reaction". En Peptides 1994, 674–75. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_309.
Texto completoActas de conferencias sobre el tema "Α/β Peptide"
Lasota, Anika, Oliwia Fraczak, Adriana Muchowska, Aleksandra Misicka, Michal Nowakowski, Maciej Maciejczyk, Andrzej Ejchart y Aleksandra Olma. "Structure-Activity Relationships of Constrained Dermorphin Analogues Containing an α-Alkyl-β-Substituted Alanines". En The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.073.
Texto completoBezeaud, A. y M. C. Guillin. "FUNCTIONAL CHARACTERIZATION OF HUMAN β-THROMBIN". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644665.
Texto completoBacon-Baguley, Theresa, Suzanne Kendra-Franczak y Daniel Walz. "THROMBOSPONDIN SPECIFICALLY INTERACTS WITH AMINO ACID SEQUENCES WITHIN THE A α- AND B β- CHAINS OF FIBRINOGEN". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643822.
Texto completoDejana, E., F. Breviario, F. Bussolino, L. Mussoni y A. Mantovani. "PLEIOTROPIC EFFECT OF INTERLEUKIN-1 ON ENDOTHELIAL CELLS". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643984.
Texto completoBerndt, M. C., X. Du, L. Beutler, W. J. Booth y P. A. Castaldi. "LOCALIZATION OF FUNCTIONAL DOMAINS ON HUMAN PLATELET GP Ib-IX COMPLEX BY EPITOPE ANALYSIS WITH MONOCLONAL ANTIBODIES". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642923.
Texto completoBlodgett, Karl, Timothy Zwier y Patrick Walsh. "SINGLE-CONFORMATION IR AND UV SPECTROSCOPY OF A PROTOTYPICAL HETEROGENEOUS α/β-PEPTIDE: IS IT A MIXED-HELIX FORMER?" En 71st International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2016. http://dx.doi.org/10.15278/isms.2016.mi12.
Texto completoKwon, Sunkuk, Shi Ke, Jessica P. Houston, Wei Wang, Qingping Wu, Chun Li y Eva M. Sevick Muraca. "In vivo pharmacokinetic analysis for fluorescently labeled RGD peptide targeted to the α v β 3 integrin in Kaposi"s sarcoma". En Biomedical Optics 2005, editado por David Kessel. SPIE, 2005. http://dx.doi.org/10.1117/12.589399.
Texto completoHantgan, R. R. "LOCALIZATION OF THE DOMAINS OF FIBRIN INVOLVED IN BINDING TO PLATELETS". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643773.
Texto completoValensin, Daniela, Henryk Kozlowski, Isabella Tessari, Simone Dell'Acqua, Luigi Bubacco, Luigi Casella, Elena Gaggelli y Gianni Valensin. "Interactions of metal ions with α synuclein and amyloid β peptides". En INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2014 (ICCMSE 2014). AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4897691.
Texto completoHan, Zhihao, Shuaishuai Gong, Zhiyu Qian y Yueqing Gu. "Virtual screened peptides with high affinity to integrin α 5 β 1 for precise tumor identification and treatment". En Biophotonics and Immune Responses XV, editado por Wei R. Chen. SPIE, 2020. http://dx.doi.org/10.1117/12.2544502.
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