Academic literature on the topic 'Β-strand'
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Journal articles on the topic "Β-strand"
Zhang, Ning, Shan Gao, Lei Zhang, Jishou Ruan, and Tao Zhang. "Statistical Analysis of Terminal Extensions of Protein β-Strand Pairs." Advances in Bioinformatics 2013 (January 28, 2013): 1–7. http://dx.doi.org/10.1155/2013/909436.
Full textKEDARISETTI, KANAKA DURGA, MARCIN J. MIZIANTY, SCOTT DICK, and LUKASZ KURGAN. "IMPROVED SEQUENCE-BASED PREDICTION OF STRAND RESIDUES." Journal of Bioinformatics and Computational Biology 09, no. 01 (February 2011): 67–89. http://dx.doi.org/10.1142/s0219720011005355.
Full textTerwilliger, Thomas C. "Rapid model building of β-sheets in electron-density maps." Acta Crystallographica Section D Biological Crystallography 66, no. 3 (February 12, 2010): 276–84. http://dx.doi.org/10.1107/s0907444910000302.
Full textVischer, Henry F., Joke C. M. Granneman, and Jan Bogerd. "Opposite Contribution of Two Ligand-Selective Determinants in the N-Terminal Hormone-Binding Exodomain of Human Gonadotropin Receptors." Molecular Endocrinology 17, no. 10 (October 1, 2003): 1972–81. http://dx.doi.org/10.1210/me.2003-0172.
Full textGao, Yang, Yanxiang Cui, Tara Fox, Shiqiang Lin, Huaibin Wang, Natalia de Val, Z. Hong Zhou, and Wei Yang. "Structures and operating principles of the replisome." Science 363, no. 6429 (January 24, 2019): eaav7003. http://dx.doi.org/10.1126/science.aav7003.
Full textHaworth, Naomi L., and Merridee A. Wouters. "Between-strand disulfides: forbidden disulfides linking adjacent β-strands." RSC Advances 3, no. 46 (2013): 24680. http://dx.doi.org/10.1039/c3ra42486c.
Full textHAWORTH, NAOMI L., LINA L. FENG, and MERRIDEE A. WOUTERS. "HIGH TORSIONAL ENERGY DISULFIDES: RELATIONSHIP BETWEEN CROSS-STRAND DISULFIDES AND RIGHT-HANDED STAPLES." Journal of Bioinformatics and Computational Biology 04, no. 01 (February 2006): 155–68. http://dx.doi.org/10.1142/s0219720006001734.
Full textVischer, Henry F., Joke C. M. Granneman, and Jan Bogerd. "Identification of Follicle-Stimulating Hormone-Selective β-Strands in the N-Terminal Hormone-Binding Exodomain of Human Gonadotropin Receptors." Molecular Endocrinology 20, no. 8 (August 1, 2006): 1880–93. http://dx.doi.org/10.1210/me.2005-0202.
Full textChandrasekhar, Srivari, Ambadi Sudhakar, Marelli Udaya Kiran, Bathini Nagendra Babu, and Bharatam Jagadeesh. "β-Strand mimetics: formation of bend-strands in oligomers of enantiomeric β-amino acids." Tetrahedron Letters 49, no. 52 (December 2008): 7368–71. http://dx.doi.org/10.1016/j.tetlet.2008.10.031.
Full textTsai, James H., Amy Sue Waldman, and James S. Nowick. "Two New β-strand Mimics." Bioorganic & Medicinal Chemistry 7, no. 1 (January 1999): 29–38. http://dx.doi.org/10.1016/s0968-0896(98)00225-9.
Full textDissertations / Theses on the topic "Β-strand"
Chen, Hongyuan. "Development of macrocyclic β-strand calpain cysteine protease inhibitors." Thesis, University of Canterbury. Chemistry, 2011. http://hdl.handle.net/10092/5582.
Full textAitken, Steven Geoffrey. "Design, synthesis and testing of β-strand mimics as protease inhibitors." Thesis, University of Canterbury. Chemistry, 2006. http://hdl.handle.net/10092/1984.
Full textLutz, Henrik [Verfasser], Bodo [Akademischer Betreuer] Laube, and Gerhard [Akademischer Betreuer] Thiel. "Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure / Henrik Lutz ; Bodo Laube, Gerhard Thiel." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2019. http://d-nb.info/1193177863/34.
Full textGanai, Rais Ahmad. "Structural and biochemical basis for the high fidelity and processivity of DNA polymerase ε." Doctoral thesis, Umeå universitet, Institutionen för medicinsk kemi och biofysik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-97689.
Full textBlomberg, David. "Synthesis of β-turn and pyridine based peptidomimetics." Doctoral thesis, Umeå universitet, Kemi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1104.
Full textBose, Anindita. "Modulation of glycogen synthase kinase 3β (GSK3 β) activation and tau phosphorylation by double stranded RNA dependent protein kinase (PKR]." Paris 7, 2010. http://www.theses.fr/2010PA077049.
Full textPKR or double-stranded RNA dependent kinase is a pro-apoptotic kinase that controls protein translation. Previous studies revealed that activated PKR is increased in AD brains. Glycogen Synthase Kinase Aβ(CS K3β) is responsible for tau phosphorylation and PKR can indirectly activate GSK3β in cell cultures. The goal of this work was to détermine if PKR could simultaneously trigger GSK3J5 activation and tau phosphorylation and apoptosis. In AD brains, both activated kinases co-localized with phosphorylated tau in neurons. In SH-SY5Y cell cultures, tunicamycin and Api_42 activate PKR, GSK3β and induce tau phosphorylation which are both attenuated by PKR inhibitors or PKR siRNA. Our results demonstrate that PKR is able to modulate GSK3β activation, tau phosphorylation and apoptosis in neuroblastoma cells exposed to tunicamycin or Aβ PKR could represent a potent pharmacological target to attenuate neurodegeneration and tau phosphorylation
Gholami, Sara [Verfasser]. "Association of neighboring β-Strands to form the β-barrel structure of the voltage-dependent anion channel, human isoform 1 (hVDAC1) precedes membrane insertion and is largely driven by polar interactions between basic and acidic amino acid side-chains / Sara Gholami." Kassel : Universitätsbibliothek Kassel, 2020. http://d-nb.info/1232431893/34.
Full textPehere, Ashok D. "New peptide-based templates constrained into a β-strand by Huisgen cycloaddition." Thesis, 2012. http://hdl.handle.net/2440/87372.
Full textThesis (Ph.D.) -- University of Adelaide, School of Chemistry and Physics, 2012
Jones, Seth Adam. "β-strand mimicry as the basis for a universal approach to protease inhibition." Thesis, 2011. http://hdl.handle.net/2440/72156.
Full textThesis (Ph.D.) -- University of Adelaide, School of Chemistry and Physics, 2011
Lord, Rianne M., A. J. Hebden, C. M. Pask, I. R. Henderson, Simon J. Allison, S. L. Shepherd, Roger M. Phillips, and P. C. McGowan. "Hypoxia-Sensitive Metal β‑Ketoiminato Complexes Showing Induced Single-Strand DNA Breaks and Cancer Cell Death by Apoptosis." 2015. http://hdl.handle.net/10454/9491.
Full textA series of ruthenium and iridium complexes have been synthesized and characterized with 20 novel crystal structures discussed. The library of β-ketoiminato complexes has been shown to be active against MCF-7 (human breast carcinoma), HT-29 (human colon carcinoma), A2780 (human ovarian carcinoma), and A2780cis (cisplatin-resistant human ovarian carcinoma) cell lines, with selected complexes’ being more than three times as active as cisplatin against the A2780cis cell line. Selected complexes were also tested against the noncancerous ARPE-19 (retinal pigment epithelial cells) cell line, in order to evaluate the complexes selectivity for cancer cells. Complexes have also been shown to be highly active under hypoxic conditions, with the activities of some complexes increasing with a decrease in O2 concentration. The enzyme thioredoxin reductase is overexpressed in cancer cells, and complexes reported herein have the advantage of inhibiting this enzyme, with IC50 values measured in the nanomolar range. The anticancer activity of these complexes was further investigated to determine whether activity is due to effects on cellular growth or cell survival. The complexes were found to induce significant levels of cancer cell death by apoptosis with levels induced correlating closely with activity in chemosensitivity studies. As a possible cause of cell death, the ability of the complexes to induce damage to cellular DNA was also assessed. The complexes failed to induce double-strand DNA breaks or DNA cross-linking but induced significant levels of single-strand DNA breaks, indicating a mechanism of action different from that of cisplatin.
Lord RM, Hebden AJ, Pask CM, Henderson IR, Allison SJ, Shepherd SL, Phillips RM, McGowan PC
Books on the topic "Β-strand"
Herwig, Sascha. β-Strang-Ausbildung eines Faltungsintermediates von BamA. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29029-0.
Full textHerwig, Sascha. β-Strang-Ausbildung eines Faltungsintermediates von BamA: Adsorption an Lipidmembranen induziert lokale Sekundärstruktur in β-Strang 9. Springer Spektrum, 2020.
Find full textBook chapters on the topic "Β-strand"
Loughlin, Wendy A., and David P. Fairlie. "Recent Advances in β-Strand Mimetics." In Amino Acids, Peptides and Proteins in Organic Chemistry, 129–47. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527631827.ch3.
Full textDel Valle, Juan R. "Heterocyclic Extended Peptide Surrogates for β-Strand Stabilization." In Topics in Heterocyclic Chemistry, 25–49. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_163.
Full textPehere, Ashok D., and Andrew D. Abell. "Macrocyclic Protease Inhibitors Constrained into a β-Strand Geometry." In Proteases in Health and Disease, 181–92. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9233-7_11.
Full textChoi, Yoonjoo. "Computational Identification and Design of Complementary β-Strand Sequences." In Methods in Molecular Biology, 83–94. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1855-4_4.
Full textBionda, Nina, and Rudi Fasan. "Peptidomimetics of α-Helical and β-Strand Protein Binding Epitopes." In Small Molecule Medicinal Chemistry, 431–64. Hoboken, NJ: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118771723.ch15.
Full textHuggins, Kelly N., and Niels H. Andersen. "Quantitating Amino Acid β-Strand Preferences, Turn Propensities and Cross-Strand Interactions in a Designed Hairpin Peptide." In Advances in Experimental Medicine and Biology, 71–72. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-73657-0_31.
Full textUrban, Jan, Hiroshi Nakanishi, Cyprian O. Ogbu, Geoffrey Kozu, Kenneth Farber, Polina Kazavchinskaya, and Min S. Lee. "Bicyclic β-Strand Templates: Epimerization and Biological Activity of Non-Electrophilic Serine Protease Inhibitors." In Peptides: The Wave of the Future, 634–35. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_295.
Full textHerwig, Sascha. "Einleitung." In β-Strang-Ausbildung eines Faltungsintermediates von BamA, 1–18. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29029-0_1.
Full textHerwig, Sascha. "Material und Methoden." In β-Strang-Ausbildung eines Faltungsintermediates von BamA, 19–28. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29029-0_2.
Full textHerwig, Sascha. "Ergebnisse." In β-Strang-Ausbildung eines Faltungsintermediates von BamA, 29–43. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29029-0_3.
Full textConference papers on the topic "Β-strand"
Seo, Yuji, Keita Yoshizaki, Keisuke Tamari, Yutaka Takahashi, Keisuke Otani, Masahiko Koizumi, and Kazuhiko Ogawa. "Abstract 5205: Poly(ADP-ribose) polymerase inhibitors induce β-radiosensitization through an altered selection of DNA double-strand break repair pathways." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5205.
Full textHwang, Wonmuk, and Matthew J. Lang. "Mechanism of Force Generation in Kinesin Motility." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175543.
Full textREVA, BORIS, and SID TOPIOL. "RECOGNITION OF PROTEIN STRUCTURE: DETERMINING THE RELATIVE ENERGETIC CONTRIBUTIONS OF β-STRANDS, α-HELICES AND LOOPS." In Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 1999. http://dx.doi.org/10.1142/9789814447331_0016.
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