Relevant bibliographies by topics / Α-hydroxyketones

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  1. Journal articles

Academic literature on the topic 'Α-hydroxyketones'

Author: Grafiati
Published: 14 April 2023

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Journal articles on the topic "Α-hydroxyketones"

1

Huang, Jinwen, Fanhong Wu, Zhongyuan Li та ін. "Indium-Mediated Reformatsky Reaction of Iododifluoro Ketones with Aldehydes: Preparation of α,α-Difluoro-β-hydroxyketone Derivatives in Water". SynOpen 06, № 01 (2022): 19–30. http://dx.doi.org/10.1055/s-0040-1719888.

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AbstractIndium can efficiently mediate the Reformatsky reaction of iododifluoroacetylketones with aldehydes to afford the corresponding α,α-difluoro-β-hydroxyketones in high yield in pure water This reaction has excellent substrate suitability and functional group selectivity and provides an efficient approach for the synthesis of bioactive molecules containing the α,α-difluoro-β-hydroxyketone pharmacophore.
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2

Kam, Mei Kee, Akira Sugiyama, Ryouta Kawanishi та Kazutaka Shibatomi. "Asymmetric Synthesis of Tertiary α -Hydroxyketones by Enantioselective Decarboxylative Chlorination and Subsequent Nucleophilic Substitution". Molecules 25, № 17 (2020): 3902. http://dx.doi.org/10.3390/molecules25173902.

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Chiral tertiary α-hydroxyketones were synthesized with high enantiopurity by asymmetric decarboxylative chlorination and subsequent nucleophilic substitution. We recently reported the asymmetric decarboxylative chlorination of β-ketocarboxylic acids in the presence of a chiral primary amine catalyst to obtain α-chloroketones with high enantiopurity. Here, we found that nucleophilic substitution of the resulting α-chloroketones with tetrabutylammonium hydroxide yielded the corresponding α-hydroxyketones without loss of enantiopurity. The reaction proceeded smoothly even at a tertiary carbon. The proposed method would be useful for the preparation of chiral tertiary alcohols.
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3

Zheng, Shasha, Wietse Smit, Anke Spannenberg, Sergey Tin та Johannes G. de Vries. "Synthesis of α-keto aldehydes via selective Cu(i)-catalyzed oxidation of α-hydroxy ketones". Chemical Communications 58, № 29 (2022): 4639–42. http://dx.doi.org/10.1039/d2cc00773h.

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4

Naveen, Naganaboina, та Rengarajan Balamurugan. "Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF4)". Organic & Biomolecular Chemistry 15, № 9 (2017): 2063–72. http://dx.doi.org/10.1039/c7ob00140a.

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5

Tanaka, Toru, Masami Kawase та Satoru Tani. "α-Hydroxyketones as inhibitors of urease". Bioorganic & Medicinal Chemistry 12, № 2 (2004): 501–5. http://dx.doi.org/10.1016/j.bmc.2003.10.017.

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6

Oelerich, Jens, та Gerard Roelfes. "Alkylidene malonates and α,β-unsaturated α′-hydroxyketones as practical substrates for vinylogous Friedel–Crafts alkylations in water catalysed by scandium(iii) triflate/SDS". Organic & Biomolecular Chemistry 13, № 9 (2015): 2793–99. http://dx.doi.org/10.1039/c4ob02487g.

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7

Tsukamoto, Takashi, Takashi Yamazaki та Tomoya Kitazume. "Enzymic Optical Resolution of α,α-Difluoro-β-Hydroxyketones". Synthetic Communications 20, № 20 (1990): 3181–86. http://dx.doi.org/10.1080/00397919008051543.

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8

Iseki, Katsuhiko, Daisuke Asada та Yoshichika Kuroki. "Preparation of optically active α,α-difluoro-β-hydroxyketones". Journal of Fluorine Chemistry 97, № 1-2 (1999): 85–89. http://dx.doi.org/10.1016/s0022-1139(99)00033-0.

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9

Li, Heng, Nan Liu, Xian Hui, and Wen-Yun Gao. "An improved enzymatic method for the preparation of (R)-phenylacetyl carbinol." RSC Advances 7, no. 52 (2017): 32664–68. http://dx.doi.org/10.1039/c7ra04641c.

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10

Muschallik, Lukas, Denise Molinnus, Melanie Jablonski та ін. "Synthesis of α-hydroxy ketones and vicinal (R,R)-diols by Bacillus clausii DSM 8716T butanediol dehydrogenase". RSC Advances 10, № 21 (2020): 12206–16. http://dx.doi.org/10.1039/d0ra02066d.

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