Journal articles on the topic 'Zeuch method'

Bosch and Zeuch method–based flowmeters use the pressure rise triggered by the injection event in a different way in order to characterize the injected flow-rate time history. These typologies of measurement are the most widely applied to evaluate the injection rate of fuel injection systems. The injection rate of a Common Rail electroinjector has been measured with both Bosch and Zeuch method–based flowmeters. The objective has been to perform a benchmark on these two different flow-rate measuring principles. A slight reduction in the rising slope of the injected flow-rate, an anomalous tail at the end of the injection and a time delay in the flow-rate trace have been observed in the case of the Bosch method measurement. A one-dimensional numerical model of the hydraulic circuit of the flowmeter based on the Bosch method has been developed and validated successfully. This model has then been applied to study the cause and effect relationships between the features of the flowmeter hydraulic circuit and the alteration in the measured injected flow-rate pattern. Design keys for the optimization of the Bosch-based flowmeters are provided, even though the investigation has definitely assessed the superior accuracy of Zeuch method–based flowmeters, at least for the examined working conditions.

The rate of injection profile is a key parameter describing the fuel injection process for diesel injection. It is also an essential input parameter for computational fluid dynamics simulations of spray flows. In the present work, rate of injection profiles of a multi-hole diesel injector were measured using the Zeuch method and the momentum flux method. The rate of injection profiles measured by the momentum flux method had a faster rise in rate of injection during the initial ramp-up phase than with the Zeuch method. The measured rate of injection profiles were applied in three-dimensional computational fluid dynamics simulations of diesel sprays under non-vaporizing and vaporizing conditions with sweeps in injection pressure, bulk charge gas density, and bulk charge gas temperature. Analytical results were compared against experimental data for liquid penetration generated under those conditions. Computational fluid dynamics results with the rate of injection profile measured by the Zeuch method under-predict liquid penetration during the initial ramp-up phase, while computational fluid dynamics results with the rate of injection profiles measured by the momentum flux method showed much better agreement with the experimental data of liquid length and penetration. This suggests that current computational fluid dynamics spray models may be able to more accurately model transient liquid penetration when using the velocity profile developed from momentum flux measurements. Further study is needed to evaluate how computational fluid dynamics predictions of combustion and emissions of affected when using these two rate of injection profiles.

Al Wolters recently suggested that Zech. 1.11c, ‘all the earth is at rest and quiet’, alludes to Isa. 14.7. His interpretation, however, does not fit well with the context of Zechariah's vision and does not take into account canonical Zechariah's method of allusion. This article offers a reinterpretation of the allusion proposed by Wolters in light of these two things. Further, it seeks to establish two additional Jeremian texts to which Zechariah alludes, both of which fit the allusive mold cast by Zechariah's use of Isaiah.

On average, houses including those in the tropics are responsible for almost 39% of the global carbon emission caused by non-renewables, first and foremost by fuel. Looking at the worldwide map of residential buildings’ contribution compared with commercial, the worldwide national maximum of 33.5% CO2 of housing is caused by residential buildings in Uzbekistan. In an overwhelming number of most countries, their values are significantly lower, due to comparably lower energy demand than commercial buildings and because affordable homes increasingly use small PV to cater for their own basic needs. However, with the rising temperature and a likewise growing imperative to cool homes from about 30 °C onwards basically by split-unit air conditioners, the residential houses’ portion of CO2-emission might dramatically increase to survive such more common hot periods in the future. In combination with air conditioners needing some airtightness, the first purpose of this entry is to show that by 2050 in tropical regions, there will be no alternative to relatively airtight houses if the temperatures rise at the present speed. This is one alternative to an uncontrollable and life-threatening migration of millions of people to cooler but still livable regions in 2050. To trigger necessary changes toward homes that can better avert the heat, using the method of qualitative comparative content analysis, passive houses (PH) have emerged as adaptations to the tropical climate. Therefore, the second purpose of this in-depth study with the perspective of social science, is to reveal a comparative closer qualitative look at the tropicalized PH-approach. It is probably the most civilized building energy-saving strategy on the planet and can systematically keep the threatening increasing heat outside. However, before utilizing the concept, herein need to investigate why PH-technology as a whole concept with all its modules discussed earlier has been very slow to “go South” into the tropical region (the original PH will be referred to as “PH1”). The reason is that some qualitative differences of the more affordable and more simplistic tropicalized “PH2” make it easier and more realistic to penetrate the market, without letting go meaningful R&D-insights of PH1. As a probably facilitating future solution, the result is the triple-tabled option to utilise more synergies between the usually closed PH1 and the more open and flexibly naturally ventilated PH2. Unlike the PH-platform, ZEMCH is a related concept which tries to cater specifically to the significantly growing market for lower-income homes to go for carbonless energy. The conclusion is that scaling for residential buildings as mass products using passive house technology in combination with ZEMCH could turn out to become an important topic. It comprises the question in how far low or no carbon affordable homes based on the PH-concept in combination with ZEMCH-applications also may come into play as standard and to help mother Earth’s struggle for survival.

In the last decades, the initial phase of the design process has been discussed from the point of view of the construction process economy contribution. In this sense, several authors highlight the decisions made at this stage as an impacting point of influence on the direct cost of the building. This concern is repeated in the cases investigated by the ZEMCH (Zero Energy Mass Custom Homes) group in Brazil, which is focused on social housing, consequently, cost becomes a fundamental factor that must be considered on these buildings’ life cycle. Furthermore, ZEMCH’s workshops in Brazil have characterized the initial phase of the design process as a process that requires speed and simultaneous control of a large amount of data by the designers. Over these perspectives, the objective of this work in progress is to verify the potential of a diagrammatic artifact as an intuitive tool of visualizing information and supporting decision making in the initial phase of the urban land subdivision design process, to obtain energy efficiency during the building’s life cycle. Therefore, diagramming information of the environmental conditions into a visualization tool, helps designers to deal with requirements of this phase and cause impact on the operational cost of the building. This research was conducted over the Design Science Research method, and concludes that although visualizing information with the aid of an artifact can play an important role for the practical requirements of the early design phases, the solution can be potentially expanded to other purposes such as teaching, and even for users self-awareness on the operational impact.

The article contains an overview of Christian commentaries on the Gospel accounts about Jesus’ triumphal entry into Jerusalem, presenting a particularly noteworthy case of intersection of two principal exegetical traditions, namely the typological and the allegorical one. The story is cited in the Gospels as an incontestable proof of the literal fulfillment of the Old Testament messianic prophecy on the forthcoming King, sitting upon a donkey and its colt (Zech 9:9 according to Matth 21:1-11). Later exegetes come to search a figural meaning of this story by associating two mounts respectably with the Jewish people and the Christians (representing the new God’s chosen people). Such an interpretation was obviously inspired by the solid tradition typological exegesis, where the topic of two rival peoples, represented by the pairs of the biblical patriarchs’ rival sons, have being treated constantly. But the formal transferring of the standard typological meaning to the Gospel story on the Lord’s entry into Jerusalem attested a lacking comprehension of the practical value of the typological method, which was primary aimed to reveal the hidden prophetic and not simply symbolic sense of the Sacred history. The only attempt to connect these interpretations with a typological norm was made by John Chrysostom, who admitted the possibility of discovering a particular kind of prophecies, announced through deeds, not only in the Old, but also in the New Testament. However, even he does not take in account another essential feature of typological interpretations, which not only expanded the range of the so called Tesimonia, proving the validity of Christian belief in the actual coming of the Messiah, but also aimed to provide a justification of Christian claims to the role of the new God-chosen people for the Jewish opponents, for whom the reference to the allegorical meaning of the events of the New Testament history could not have served as a convincing argument.

191 Background: For 10-15% of cancer patients, pain cannot be controlled using existing therapies (Zech et al., Pain, 63, 65-76, 1995). SP-SAP is the first targeted toxin to undergo phase I testing for pain. SP-SAP (Wiley and Lappi, Neurosci Lett, 230, 97-100, 1997) covalently linkes substance P (SP), a neuromodulator that binds to NK1 receptors on laminae I and X of the dorsal horn, and saporin (SAP), a ribosomal toxin that ablates cells that express NK1 and endocytose the toxin. Intrathecal injections of SP-SAP in rats reduce chemically or thermally induced pain, thermal hyperalgesia, and mechanical allodynia, with no signs of motor, sensory, or behavioral dysfunction (Mantyh et al., Science, 278, 275-9, 1997; Nichols et al., Science, 286, 1558-61, 1999; Suzuki et al., Nature Neurosci, 5, 139-26, 2002; Vierck et al., Neurosci, 199, 223-32, 2003). In canines, intrathecal injections into the lumbar region – 45 mcg for 10-15 kg (Allen et al., Toxicol Sci, 91, 286-98, 2006) or 15 mcg for 8-12 kg (Wiese et al., Anesthesiol, 119, 1163-77, 2013) – produce no neurological, behavioral, or histological deficits. A double-blinded RCT of SP-SAP for the treatment of bone pain in canines (Brown and Agnello, Anesthesiol, 199, 1178-85, 2013) showed that a single injection of 60 mcg (above 30 kg) or 40 mcg (below 30 kg) significantly reduced pain as measured by time to owner unblinding (p=0.002) or number of canines unblended (p=0.001). Methods: A single intrathecal injection of SP-SAP is made at the L5-S1 interspace of cancer patients with intractable sub-umbilical pain. Single subject cohorts are at doses of 1, 2, 4, 8, 16, 32, 64, and 90 mcg. Primary outcomes are assessed by pain survey (VAS “bothersome pain”, VAS “pain intensity”, ODI, EQ-5D, and BDI) and medication use log. Patients are monitored for toxicity, neurological and cardiac abnormalities, and SP-SAP antibodies for 6 months. Results: This report presents the results from the first three subjects of the phase I study. No evidence of toxicity or neurological or cardiac abnormalities were found. No clear evidence for pain reduction was observed. Conclusions: At existing doses (< 4 mcg), SP-SAP appears safe for human use. The study is continuing with dose escalation. Clinical trial information: NCT02036281.

Category: Basic Sciences/Biologics Introduction/Purpose: Weight-bearing CT (WBCT) has been proven to allow for more precise and valid measurement of bone position (angles) than conventional weight-bearing radiographs (R) and conventional CT without weight-bearing (CT)1. The measurement by hand (MBH) has demonstrated adequate inter- and intraobserver reliability but high time consumption1. Recently, a semi-automatic software-based angular measurement (SAM) has been developed (Disior Ltd, Helsinki, Finland). The purpose of this study was to compare SAM with MBH regarding angles values and time spent for the investigator. Methods: Fifteen bilateral WBCT scans (PedCAT, Curvebeam, Warrington, PA, USA) were randomly extracted from a local institutional database with more than 13,000 scans. Nineteen angles as shown in table 1 were measured with MBH as previously described and with SAM1. SAM includes software generated 3D models with semi-automatic bone specification of tibia, fibula, talus, calcaneus, navicular, cuboid, cuneiforms and metatarsals. The software automatically defines the longitudinal axes of these bones and automatically measures the angles between these axes. The time spent of the investigator for the measurements was recorded (total process MBH and specification of bones for SAM). The software calculation time for SAM was not measured or considered as investigator time spent. The angles and time spent of MBH and SAM were compared (t-test, homoscedatic). Results: Mean age of the subject was 58 years (range, 7-81), 12 (40%) were male. The pathologies were bilateral in 8 (54%), right in 4 (27%) and left in 3 (20%) subjects (23 feet in total) and were specified as follows, ankle osteoarthritis/instability in 6 (26%), Haglund deformity/Achillodynia in 4 (17%), Forefoot deformity in 7 (30%), Charcot arthropathy in 2 (9%), flatfoot in 4 (17%) feet. The angles did not differ between MBH and SAM (Table 1, each p>.05). The time spent for MBH / SAM was 780+-171s / 20+-8 s on average in total for 19 angles and 41+-9s / 1+-0.4 s per angle (p<.01). Conclusion: This is the first study comparing MBH with SAM. SAM shows similar angles as MBH and can be also considered as reliable measurement option. The investigator time spent is 97% lower for SAM (1 s per angle) than for MBH (41 s per angle). SAM is an important step forward for 3D-angle measurement of WBCT. The next desired is fully automatic software-based measurement. References1. Richter M, Seidl B, Zech S, Hahn S. PedCAT for 3D-Imaging in Standing Position Allows for More Accurate Bone Position (Angle) Measurement than Radiographs or CT. Foot Ankle Surg 2014;20:201-7. [Table: see text]

The effects of biochar and biochar combined with N-fertilizer on the content of soil organic matter in water-stable aggregates were investigated. A field experiment was conducted with different biochar application rates: B0 control (0 t ha-1), B10 (10 t ha-1) and B20 (20 t ha-1) and 0 (no N), 1st and 2nd levels of nitrogen fertilization on silt loam Haplic Luvisol (Dolna Malanta, Slovakia), in 2014. The N doses of level 1 were calculated on required average crop production using balance method. Level 2 included additional 100% of N in year 2014 and additional 50% of N in year 2016. The effects were investigated during the growing seasons of spring barley and spring wheat in 2014 and 2016, respectively. Results indicate that the B20N2 treatment significantly increased the proportion of water-stable macro-aggregates (WSAma) and reduced water-stable micro-aggregates (WSAmi). Aggregate stability increased only in the B20N1 treatment. The B20N2 treatment showed a robust decrease by 27% in the WSAma of 0.5-0.25 mm. On the other hand, an increase by 56% was observed in the content of WSAma with fractions 3-2 mm compared to the B0N0 treatment. The effect of N fertilizer on WSAma was confirmed only in the case of the B10N2 treatment. The proportion of WSAma with fractions 3-2 mm decreased by 42%, while the size fraction of 0.5-0.25 mm increased by 30% compared to the B10N0 treatment. The content of WSAma with fractions 1-0.5 mm decreased with time. On the contrary, the content of WSAma with particle sizes above 5 mm increased with time in all treatments except the B10N2 and B20N2 treatments. A statistically significant trend was identified in the proportion of WSA in the B10N2 and B20N2 treatments, which indicates that biochar with higher application levels of N fertilizer stabilizes the proportion of water-stable aggregates. 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Abstract Background Scholars agree that Torbjörn Caspersson’s lab at the Institute of Medical Cell Research and Genetics at the Karolinska Institute, Sweden, played a key role in the first description of the so-called Q-banding technique. It laid the foundation for a new era of cytogenetic diagnostics and had a lasting impact in several areas of biology and medicine. Methods Based on a mixed-method approach, essential aspects of the history of human cytogenetics are considered via primary and secondary analysis of biographical interviews as well as the qualitative evaluation of bibliometrics. Drawing on interviews with colleagues of lab member Lore Zech (1923–2013) and contemporary publications, this paper illuminates the role of and contribution by Zech: To what extent is the discovery attached to her and what does her legacy look like today? Results The analysis of the contemporary witness interviews with colleagues, students and junior researchers shows that Lore Zech was a committed member of Caspersson's research group. In addition, memoirs by contemporary colleagues describe her outstanding skills in microscopy. The different sources paint a multifaceted picture. In addition to the historians' patterns of interpretation, different legacies can also be found within the peer group. Conclusions We argue that Zech represent the type of scientist who, although her research was acknowledged with several prizes, so far has not been part of the canon of pioneers of international cytogenetics.