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Sporrel, Karlijn, Shihan Wang, Dick D. F. Ettema, Nicky Nibbeling, Ben J. A. Krose, Marije Deutekom, Rémi D. D. de Boer, and Monique Simons. "Just-in-Time Prompts for Running, Walking, and Performing Strength Exercises in the Built Environment: 4-Week Randomized Feasibility Study." JMIR Formative Research 6, no. 8 (August 1, 2022): e35268. http://dx.doi.org/10.2196/35268.
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Background App-based mobile health exercise interventions can motivate individuals to engage in more physical activity (PA). According to the Fogg Behavior Model, it is important that the individual receive prompts at the right time to be successfully persuaded into PA. These are referred to as just-in-time (JIT) interventions. The Playful Active Urban Living (PAUL) app is among the first to include 2 types of JIT prompts: JIT adaptive reminder messages to initiate a run or walk and JIT strength exercise prompts during a walk or run (containing location-based instruction videos). This paper reports on the feasibility of the PAUL app and its JIT prompts. Objective The main objective of this study was to examine user experience, app engagement, and users’ perceptions and opinions regarding the PAUL app and its JIT prompts and to explore changes in the PA behavior, intrinsic motivation, and the perceived capability of the PA behavior of the participants. Methods In total, 2 versions of the closed-beta version of the PAUL app were evaluated: a basic version (Basic PAUL) and a JIT adaptive version (Smart PAUL). Both apps send JIT exercise prompts, but the versions differ in that the Smart PAUL app sends JIT adaptive reminder messages to initiate running or walking behavior, whereas the Basic PAUL app sends reminder messages at randomized times. A total of 23 participants were randomized into 1 of the 2 intervention arms. PA behavior (accelerometer-measured), intrinsic motivation, and the perceived capability of PA behavior were measured before and after the intervention. After the intervention, participants were also asked to complete a questionnaire on user experience, and they were invited for an exit interview to assess user perceptions and opinions of the app in depth. Results No differences in PA behavior were observed (Z=−1.433; P=.08), but intrinsic motivation for running and walking and for performing strength exercises significantly increased (Z=−3.342; P<.001 and Z=−1.821; P=.04, respectively). Furthermore, participants increased their perceived capability to perform strength exercises (Z=2.231; P=.01) but not to walk or run (Z=−1.221; P=.12). The interviews indicated that the participants were enthusiastic about the strength exercise prompts. These were perceived as personal, fun, and relevant to their health. The reminders were perceived as important initiators for PA, but participants from both app groups explained that the reminder messages were often not sent at times they could exercise. Although the participants were enthusiastic about the functionalities of the app, technical issues resulted in a low user experience. Conclusions The preliminary findings suggest that the PAUL apps are promising and innovative interventions for promoting PA. Users perceived the strength exercise prompts as a valuable addition to exercise apps. However, to be a feasible intervention, the app must be more stable.
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Pradeep, K., MA Kuttappa, Adarsh Kudva, and Roshni Butula. "In vitro Comparison of Compressive Strength of Bulk-fill Composites and Nanohybrid Composite." World Journal of Dentistry 7, no. 3 (2016): 119–22. http://dx.doi.org/10.5005/jp-journals-10015-1378.
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ABSTRACT Objectives The objective of this study is to measure and compare the compressive strength of two bulk-fill posterior composites (Smart dentin replacement or SDR and Filtek bulk fill) with universal nanohybrid composite (Filtek Z 250XT). Materials and methods In this in vitro study, three different types of posterior composites are used as follows: Group 1 – SDR (Dentsply, Konstanz, Germany); group 2 – Filtek bulk-fill (3M ESPE, St. Paul, MN, USA); group 3 – Filtek Z-250XT (3M ESPE, St. Paul, MN, USA). Ten cylindrical samples of 6 mm height and 4 mm diameter in each group were made using a split brass mold. The composites filled in the brass mold were photopolymerized using light-emitting diode (LED) light-curing unit and the cured samples were stored in water at 37°C for 48 hours before testing. The compressive strength of the stored samples was tested using universal testing machine (Instron 3366, UK) at a cross-head speed of 0.5 mm/minute. The compressive strength was calculated by dividing the maximum load with area of the samples. Results Results are statistically analyzed using one-way analysis of variance (ANOVA) with Tukey's post hoc test. Analysis showed that SDR and Filtek bulk-fill have greater compressive strength than Filtek Z-250 (p < 0.05). However, there is no statistical difference between compressive strength of SDR and Filtek bulk-fill composites (p > 0.05). How to cite this article Pradeep K, Ginjupalli K, Kuttappa MA, Kudva A, Butula R. In vitro Comparison of Compressive Strength of Bulk-fill Composites and Nanohybrid Composite. World J Dent 2016;7(3):119-122.
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Maron, Marcin. "Filmowa neoawangarda i początki sztuki video." Annales Universitatis Mariae Curie-Sklodowska, sectio L – Artes 15, no. 2 (September 19, 2018): 37. http://dx.doi.org/10.17951/l.2017.15.2.37.
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<p>Artykuł w syntetyczny sposób omawia najważniejsze zjawiska filmu eksperymentalnego w kontekście pojęcia i praktyki sztuki neoawangardowej od II połowy lat 60. do połowy lat 70. XX wieku. Na początku przypomniana została pierwsza i druga faza rozwoju filmu eksperymentalnego w związku z istnieniem tzw. Wielkiej Awangardy oraz z działalnością jej kontynuatorów po Ii wojnie światowej w USA. Nastepnie zdefiniowane zostało pojęcie neoawangardy w odniesieniu do ujęcia, które zparoponował Frank Popper. W dalszej części artykułu jego autor omawia zasady oraz najważniejsze przykłady filmów neoawangardowych m. in: film strukturalny, kino porzeszone, intermedia. Ważną częścią artykułu jest przedstawienie początków, idei oraz najważniejszych rodzajów sztuki video. W artykule omówione zostały filmy takich autorów jak m. in. Paul Sharits, Peter Kubelka, Peter Campus, Bill Viola i innych.</p><p> </p><strong>Film Neo-Avant-garde and the Beginnings of Video Art</strong><p>SUMMARY</p><p>The article comprehensively discusses the most important phenomena of experimental film in the context of the concept and practice of neo-avant-garde art from the latter half of the nineteen-sixties to the mid-nineteen-seventies. The paper begins by referring to the first and second phase of the development of experimental film in connection with the existence of the so-called Great Avant-garde and the activity of its continuators after World War Two in the USA. The text then defines the concept of neo-avant-garde in relation to the interpretation proposed by Frank Popper. The article then discusses the principles and the most important examples of neo-avant-garde films, inter alia structural film, widened cinema, or intermedia. An important part of the article is the presentation of the beginnings, idea and the major types of video art. The paper also discusses the films by such authors as inter alia Paul Sharits, Peter Kubelka, Peter Campus, Bill Viola, and others.</p>
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Skok, Kristijan, Nina Skornšek, Marko Hočevar, and Pavel Skok. "Hipertermična intraperitonealna kemoterapija." Slovenian Medical Journal 88, no. 1-2 (March 4, 2019): 21–38. http://dx.doi.org/10.6016/zdravvestn.2836.
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V preteklosti so bolnike z zasevki po peritoneju obravnavali kot neozdravljivo bolne s terminalnim stanjem raka, ki se zdravi samo paliativno. Ob takšnem pristopu je bilo povprečno preživetje bolnikov le dva meseca. Zdravljenje teh bolnikov se je v devetdesetih letih prejšnjega stoletja pomembno spremenilo. Nekateri raziskovalci so bili namreč mnenja, da so peritonealni zasevki v določenih primerih samo vrsta loko-regionalne bolezni in se bolnik lahko (p)ozdravi. Eden glavnih zagovornikov te teorije in novega načina zdravljenja je bil Paul Sugarbaker. V sklopu zdravljenja se je začela uporabljati citoreduktivna kirurgija v kombinaciji z intraperitonealno kemoterapijo. Namen kirurškega posega je bila makroskopska odstranitev tumorja, nato pa z intraperitonealno kemoterapijo odstranitev še morebitnih mikroskopskih “preostankov” bolezni. Postopek, pri katerem citostatik med operacijo uvedemo in segrevamo, se imenuje hipertermična intraperitonealna kemoterapija. Hipertermija ima že sama po sebi protitumorski učinek na maligne celice, saj povzroči razgradnjo proteinov, aktivranje lizosomov in apoptozo. Ob segrevanju raztopine citostatika potečejo zapletene kemijske reakcije, ki dodatno povečajo njegovo učinkovitost in povečajo globino prodiranja zdravila v tumorsko tkivo. O najboljših rezultatih te oblike zdravljenja so poročali v primerih psevdomiksoma peritoneja, raka debelega črevesa in danke, karcinoma slepiča, karcinoma jajčnikov in peritonealnega mezotelioma. V prispevku avtorji predstavijo to zahtevno metodo zdravljenja, indikacije in vključitvena merila bolnikov ter sodobna spoznanja o učinkovitosti te metode za določene vrste raka.
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Wang, Zhongyang, Ge Sun, Mrinmay Mandal, Paul Kohl, Juan de Pablo, Shrayesh N. Patel, and Paul F. Nealey. "Role of Water Molecules in Enabling Site Hopping and Vehicular Transport Mechanisms in Polynorbornene-Based Anion Exchange Membrane." ECS Meeting Abstracts MA2022-02, no. 41 (October 9, 2022): 1536. http://dx.doi.org/10.1149/ma2022-02411536mtgabs.
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Role of Water Molecules in Enabling Site Hopping and Vehicular Transport Mechanisms in Polynorbornene-based Anion Exchange Membrane Zhongyang Wang, ⸹ Ge Sun ， ⸹ Mrinmay Mandal, ‡, Paul A. Kohl, ‡, Juan de Pablo, ⸹ Shrayesh N. Patel, ⸹ and Paul F. Nealey ⸹ ‡ School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, 30332-0100, United States ⸹ Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, USA Ion exchange membranes are at the heart of electrochemical conversion and storage devices such as fuel cells 1, water electrolyzers 2, CO2 electrolyzers 3. redox flow batteries 4, and reverse electrodialysis 5. Anion exchange membrane fuel cells (AEMFCs) have attracted enormous attention as alternatives to replace perfluorinated, sulfonic acid-based proton exchange membrane fuel cells (PEMFCs) 6 because alkaline membrane electrode assemblies (MEAs) composed of anion exchange ionomers (AEIs) and AEMs that allow the use of Ni 7, 8, Fe 9, and Ag 10 based precious-group-metal (PGM) free catalysts in alkaline environments for hydrogen oxidation reactions (HORs) and oxygen reduction reactions (ORRs). However, the lack of understanding of ion transport mechanisms at different hydration levels of an anion exchange membrane hinders the rational design of the MEAs in an AEMFC. Here we investigate site hopping and vehicular transport mechanisms using anion exchange thin films, interdigitated electrodes, and atomistic molecular dynamics simulations. Halide ion (Br-, Cl- and I-) conductivities in polynorbornene-based thin films are measured as a function of temperature and relative humidity using electrochemical impedance spectroscopy. Halide ions show Arrhenius behaviors, and activation energy (Ea) is for the first time used as an indicator for detecting the transition of site hopping and vehicular transport mechanisms. Using atomistic molecular dynamics simulation, we quantitatively demonstrate that the transition of site hopping and vehicular mechanisms is aided by better solvation environments of anions and more percolated water pathways. References Z. Wang, J. Parrondo, C. He, S. Sankarasubramanian and V. Ramani, Nature Energy, 2019, 4, 281-289. S. Z. Oener, M. J. Foster and S. W. Boettcher, Science, 2020, 369, 1099-1103. D. A. Salvatore, C. M. Gabardo, A. Reyes, C. P. O’Brien, S. Holdcroft, P. Pintauro, B. Bahar, M. Hickner, C. Bae, D. Sinton, E. H. Sargent and C. P. Berlinguette, Nature Energy, 2021, 6, 339-348. K. Lin, Q. Chen, M. R. Gerhardt, L. Tong, S. B. Kim, L. Eisenach, A. W. Valle, D. Hardee, R. G. Gordon, M. J. Aziz and M. P. Marshak, Science, 2015, 349, 1529-1532. R. D. Cusick, Y. Kim and B. E. Logan, Science, 2012, 335, 1474-1477. J. Wang, Y. Zhao, B. P. Setzler, S. Rojas-Carbonell, C. Ben Yehuda, A. Amel, M. Page, L. Wang, K. Hu, L. Shi, S. Gottesfeld, B. Xu and Y. Yan, Nature Energy, 2019, 4, 392-398. G. Braesch, Z. Wang, S. Sankarasubramanian, A. G. Oshchepkov, A. Bonnefont, E. R. Savinova, V. Ramani and M. Chatenet, Journal of Materials Chemistry A, 2020, 8, 20543-20552. S. Kabir, K. Lemire, K. Artyushkova, A. Roy, M. Odgaard, D. Schlueter, A. Oshchepkov, A. Bonnefont, E. Savinova, D. C. Sabarirajan, P. Mandal, E. J. Crumlin, Iryna V. Zenyuk, P. Atanassov and A. Serov, Journal of Materials Chemistry A, 2017, 5, 24433-24443. H. Adabi, A. Shakouri, N. Ul Hassan, J. R. Varcoe, B. Zulevi, A. Serov, J. R. Regalbuto and W. E. Mustain, Nature Energy, 2021, 6, 834-843. H. Erikson, A. Sarapuu and K. Tammeveski, ChemElectroChem, 2019, 6, 73-86.
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El-Sahn, NA, DW El-Kassas, HM El-Damanhoury, OM Fahmy, H. Gomaa, and JA Platt. "Effect of C-factor on Microtensile Bond Strengths of Low-Shrinkage Composites." Operative Dentistry 36, no. 3 (May 1, 2011): 281–92. http://dx.doi.org/10.2341/10-105-l.
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SUMMARY This study evaluated the microtensile bond strength (μ-TBS) of low-shrinkage composites with their corresponding adhesive systems, Filtek Silorane/Silorane adhesive (SIL, 3M ESPE AG, Seefeld, Germany) and Aelite LS/One-Step Plus (AL, BISCO Inc, Schaumburg, IL, USA) in cavities with different C-factors. Filtek Z250/Adper Single Bond Plus (Z, 3M ESPE, St Paul, MN, USA) was used as a control. Method Standardized Class I cavities were prepared in extracted human molars after removing occlusal enamel. Cavities were assigned into six different C-factors by applying nail polish to four walls, three walls, two walls adjacent to each other, two walls opposite to each other, one wall, or no walls. Resin composites with their corresponding adhesive systems were applied according to manufacturer instructions. Specimens were sectioned to obtain four rectangular beams from the center of the restorations and μ-TBS was measured. Data were analyzed by Weibull survival analysis. Shrinkage stresses of the resin composites were determined after 30 minutes from the start of light-curing using a tensometer testing machine. Flexure elastic modulus was determined using standard procedures, in accordance with ISO 4049. Data for shrinkage stress and elastic modulus were analyzed by one-way analysis of variance followed by a Tukey multiple-comparisons test (p<0.05). Results μ-TBS of both SIL and AL were not affected by different C-factors; however, the bond strength of Z decreased significantly when the C-factor increased. Shrinkage stress results were 0.94±0.1, 1.79±0.18, and 2.14±0.23 MPa for SIL, AL, and Z, respectively. The flexural modulus of both the SIL and the AL was significantly lower than that of Z. Conclusions Increasing C-factor did not negatively affect the bond strength of low-shrinkage composites.
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du Preez, E. D., N. C. van Rij, K. F. Lawrance, M. R. Miles, and R. D. Frederick. "First Report of Soybean Rust Caused by Phakopsora pachyrhizi on Dry Beans in South Africa." Plant Disease 89, no. 2 (February 2005): 206. http://dx.doi.org/10.1094/pd-89-0206c.
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During April 2004, a 150-m2 dry bean (Phaseolus vulgaris) plot growing adjacent to rust-infected soybean (Glycine max) at Cedara Agricultural Research Farm (29°32′S 30°16′E) was observed to be infected with two distinct rust types. Common bean rust (caused by Uromyces appendiculatus) with reddish brown uredinia and black telia was readily identified. A second rust with smaller sporulating uredinia (1.0 to 1.5 mm2), which were gray in appearance, was also found. Visual rust severity on the dry bean plants, which were in mid pod-fill, was high (approximately 30 to 40% disease incidence). Twenty plants were examined and observed to be infected with both rusts. With microscopic examination of no fewer than 20 leaves per plant, the urediniospores from the smaller lesions were determined to be morphologically similar to Phakopsora pachyrhizi (3). Real-time fluorescent polymerase chain reaction assays on six leaves and sequence analysis of the nuclear ribosomal internal transcribed spacer region 2 (1) verified the identity of the urediniospores as P. pachyrhizi. Although P. vulgaris is a known host of P. pachyrhizi, to our knowledge this is the first time since the arrival of soybean rust in 2001 that P. pachyrhizi has been observed on an alternate host plant in South Africa (2). Since dry beans are grown all year in frost-free areas, the implications are that dry beans may serve as an important overwintering host and source of inoculum for seasonal soybean rust outbreaks. References: (1) R. D. Frederick et al. Phytopathology 92:217, 2002. (2) Z. A. Pretorius et al. Plant Dis. 85:1288, 2001. (3) J. B. Sinclair and G. L. Hartman. Soybean Rust. Pages 25–26 in: Compendium of Soybean Diseases, 4th ed. G. L. Hartman et al. eds. The American Phytopathological Society, St. Paul, MN, 1999.
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Al-Araj, Anna. "Pieśni Ireny Wieniawskiej do słów Paula Verlaine'a." Annales Universitatis Mariae Curie-Sklodowska, sectio L – Artes 14, no. 1 (November 4, 2016): 91. http://dx.doi.org/10.17951/l.2016.14.1.91.
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<p> W niniejszym artykule podjęto próbę interpretacji 21 pieśni Ireny Wieniawskiej (powstałych w latach 1911-1927), wykorzystujących teksty Paula Verlaine’a. Kompozytorka (1879-1932), znana także jako Madame Poldowski czy Lady Dean Paul, była córką Henryka Wieniawskiego i Izabeli Hampton-Wieniawskiej. Żyła i pracowała w Belgii oraz Wielkiej Brytanii, odbyła także podróże koncertowe do Stanów Zjednoczonych i Hiszpanii. We Francji poznała dorobek impresjonistów (m.in. Maurice’a Ravela), co w znacznym stopniu ukształtowało jej idiom twórczy.</p><p> W pierwszej części tekstu analizie poddano warstwę słowną utworów Wieniawskiej: ich wymiar treściowy oraz konstrukcyjny. Kolejny fragment został poświęcony płaszczyźnie muzycznej – autorka charakteryzuje podstawowe elementy dzieła: melodykę, akompaniament, harmonikę, fakturę i formę. W trzeciej części artykułu, w oparciu o reguły (<em>corollaries</em>) wyznaczone przez Henry’ego Woolletta, interpretowane są relacje słowno-muzyczne w pieśniach Madame Poldowski. Przeprowadzone analizy skłaniają do przyjęcia hipotezy o związku wokalno-instrumentalnego dorobku Lady Dean Paul z gatunkiem francuskiej <em>mélodie</em>, na co wskazywałaby predylekcja kompozytorki do recytatywnego traktowania głosu solowego, sylabicznego opracowania tekstu, jak również tendencja do wykorzystywania różnorodnych, skomplikowanych rozwiązań w zakresie harmoniki i formy. Wydaje się, że estetykę twórczości pieśniowej Wieniawskiej można włączyć w krąg symbolizmu, jej elementy zaś stanowią transpozycję wyróżników tego nurtu na grunt muzyczny. </p><script type="text/javascript">// <![CDATA[
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Laska, Melissa N., Mary O. Hearst, Ann Forsyth, Keryn E. Pasch, and Leslie Lytle. "Neighbourhood food environments: are they associated with adolescent dietary intake, food purchases and weight status?" Public Health Nutrition 13, no. 11 (June 8, 2010): 1757–63. http://dx.doi.org/10.1017/s1368980010001564.
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AbstractObjectiveTo examine neighbourhood food environments, adolescent nutrition and weight status.DesignCross-sectional, observational study.SettingMinneapolis/St. Paul metropolitan region, Minnesota, USA.SubjectsA total of 349 adolescents were recruited to the study. Participants completed 24 h dietary recalls and had their weight and height measured. They also reported demographic information and other diet-related behaviours. Geographic Information Systems were used to examine the availability and proximity of food outlets, particularly those captured within the 800, 1600 and/or 3000 m network buffers around participants’ homes and schools.ResultsAdjusting for gender, age and socio-economic status, adolescents’ sugar-sweetened beverage intake was associated with residential proximity to restaurants (including fast food), convenience stores, grocery stores and other retail facilities within the 800 and/or 1600 m residential buffers (P ≤ 0·01). BMI Z-score and percentage body fat were positively associated with the presence of a convenience store within a 1600 m buffer. Other individual-level factors, such as energy, fruit and vegetable intake, as well as convenience store and fast food purchasing, were not significantly associated with features of the residential neighbourhood food environment in adjusted models. In addition, school neighbourhood environments yielded few associations with adolescent outcomes.ConclusionsMany factors are likely to have an important role in influencing adolescent dietary intake and weight status. Interventions aimed at increasing neighbourhood access to healthy foods, as well as other approaches, are needed.
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Collins, Charles T. "Chimney Swifts: America’s Mysterious Birds above the Fireplace. Louise Lindsey Merrick Natural Environment Series, Volume 37. By Paul D Kyle and , Georgean Z Kyle; illustrated by , Georgean Z Kyle; photographs by , Paul D Kyle. College Station (Texas): Texas A&M University Press. $34.00 (hardcover); $16.95 (paper). vi + 140 p; ill.; index. ISBN: 1‐58544‐370‐0 (hc); 1‐58544‐371‐9 (pb). 2005." Quarterly Review of Biology 82, no. 2 (June 2007): 156–57. http://dx.doi.org/10.1086/519608.
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Lauener, Michael. "Lauener, Michael, Schutz der Kirche und Stabilität des Staates durch Absenz von religiöser ,Seichtigkeit': die religionspolitischen Anschauungen von Jeremias Gotthelf und Georg Wilhelm Friedrich Hegel aus dem Geist der Versöhnung." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Kanonistische Abteilung 105, no. 1 (June 26, 2019): 280–349. http://dx.doi.org/10.1515/zrgk-2019-0009.
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Abstract Protection of the church and state stability through the absence of religious 'shallowness': views on religion-policy of Jeremias Gotthelf and Georg Wilhelm Friedrich Hegel out of a spirit of reconciliation. The article re-examines a thesis of Paul Baumgartner published in 1945: "Jeremias Gotthelf's, 'Zeitgeist and Bernergeist', A Study on Introduction and Interpretation", that if the Swiss writer and keen Hegel-opponent Jeremias Gotthelf had read any book of the philosopher Georg Wilhelm Friedrich Hegel, some of this would have received his recognition. Both Gotthelf and Hegel see the Reformation to be the cause of the emergence of a strong state. For Gotthelf, this marks the beginning of a process of strengthening the state at the expense of the church. Hegel, on the other hand, considers the modern state to be the reality of freedom, produced by the Christian 'religion of freedom' (Rph, §270 Z., p. 430). In contrast to Gotthelf, for whom only Christ can reconcile the state and religion, Hegel praises the French Revolution as "reconciliation of the divine with the world". For Gotthelf, the French Revolution was only a poor imitation of the process of spiritual and political liberation initiated by the Reformation, through which Christ reduced people to their original liberty. Nevertheless, both Gotthelf and Hegel want to protect the state and the church from falling apart, they reject organizational unity of state – religion – church in the sense of a theocracy, and demand the protection of church communities.
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Imamaliyeva, Samira Z., Dunya M. Babanly, Vladimir P. Zlomanov, Mahammad B. Babanly, and Dilgam B. Taghiyev. "Thermodynamic Properties of Terbium Tellurides." Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 22, no. 4 (December 15, 2020): 453–59. http://dx.doi.org/10.17308/kcmf.2020.22/3116.
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The paper presents the results of a study of solid-phase equilibria in the Tb–Te system and the thermodynamic properties of terbium tellurides obtained by the methods of electromotive forces and X-ray diffraction analysis. Based on the experimental data, it was established that the TbTe, Tb2Te3, TbTe2 и TbTe3 compounds are formed in the system. For the investigations of the alloys from the two-phase regions TbTe3+Te, TbTe2+TbTe3, and Tb2Te3+TbTe2, the EMF of concentration cells relative to the TbTe electrode was measured. The EMF of concentration cells relative to the terbium electrode was measured for the TbTe+Tb2T3 region. The partial thermodynamic functions of TbTe and Tb in alloys were determined bycombining the EMF measurements of both types in the 300–450 K temperature range, based on which the standard thermodynamic functions of formation and standard entropies of the indicated terbium tellurides were calculated.
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The electrochemicalapplications of rare earth-based nanomaterials.Analyst. 2019;144(23): 6789–6811. DOI: https://doi.org/10.1039/C9AN01562K7. Saint-Paul M., Monceau P. Survey of thethermodynamic properties of the charge density wavesystems. Adv. Cond. Matter Phys. 2019: 1–5 DOI:https://doi.org/10.1155/2019/21382648. Cheikh D., Hogan B. E., Vo T., Allmen P. V., Lee K.,Smiadak D. M., Zevalkink A., Dunn B. S., Fleurial J-P.,Bux S. L. Praseodymium telluride: A high temperature,high- ZT thermoelectric material. Joule. 2018; 2(4):698–709. DOI: https://doi.org/10.1016/j.joule.2018.01.0139. Patil S. J., Lokhande A. C., Lee D. W, Kim J. H.,Lokhande C. D. Chemical synthesis and supercapacitiveproperties of lanthanum telluride thin film. Journal ofColloid and Interface Science. 2017; 490: 147–153. DOI:https://doi.org/10.1016/j.jcis.2016.11.02010. Zhou X. Z., Zhng K. H. L, Xiog J., Park J-H,Dickerson J-H., He W. Size- and dimentionalitydependent optical, mahnetic and magneto-opticalproperties of binary europium-based nanocrystals:EuX (X=O, S, Se, Te). Nanotechnology. 2016;27(19):192001-5. DOI: https://doi.org/10.1088/0957-4484/27/19/19200111. Okamoto H. Desk handbook phase diagram forbinary alloys. ASM International. 2000. 900 p.12. Babanly M. B., Mashadiyeva L. F., Babanly D. M.,Imamaliyeva S. Z., Tagiyev D. B., Yusibov Y. A.. Someissues of complex studies of phase equilibria andthermodynamic properties in ternary chalcogenidesystems involving Emf measurements. Russian Journalof Inorganic Chemistry. 2019;64(13): 1649–1672. DOI:https://doi.org/10.1134/s003602361913003513. Imamaliyeva S. Z., Babanly D. M., Tagiev D. B.,Babanly M. B. Physicochemical aspects of developmentof multicomponent chalcogenide phases having theTl5Te3 structure. A review. Russian Journal of InorganicChemistry2018;63(13): 1703–1724 DOI: https://doi.org/10.1134/s003602361813004114. Massalski T. B. 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Electrochimica Acta. 2016;222: 1770–1775.DOI: https://doi.org/10.1016/j.electacta.2016.11.07520. Morachevsky A. G., Voronin G. F., Geyderich V. A.,Kutsenok I. B. Elektrokhimicheskie metody issledovaniyav t e r m o d i n a m i k e m e t a l l i c h e s k i k h s y s t e m .[Electrochemical methods of investigation inhermodynamics of metal systems]. Moscow:Akademkniga Publ.; 2003. 334 p. Available at: https://elibrary.ru/item.asp?id=19603291 (In Russ.)21. Babanly M. B., Yusibov Y. A. Elektrokhimicheskiemetody v termodinamike neorganicheskikh sistem[Electrochemical methods in thermodynamics ofinorganic systems]. Baku: BSU Publ.; 2011. 306 p.22. Imamaliyeva S. Z., Mehdiyeva I. F., Taghiyev D. B.et al. Thermodynamic investigations of the erbiumtellurides by EMF method. Physics and Chemistry ofSolid State. 2020;21(2): 312–318. DOI: https://doi.org/10.15330/pcss.21.2.312-31823. Hasanova G. S., Aghazade A. I., Yusibov Yu. A.,Babanly M. B. Thermodynamic investigation of theBi2Se3-Bi2Te3 system by the EMF method. Kondensirovannyesredy i mezhfaznye granitsy = CondensedMatter and Interphases. 2020;22(3): 310–319. DOI:https://doi.org/10.17308/kcmf.2020.22/296124. Imamaliyeva S. Z., Babanly D. M., Gasanly T. M.,et al.: Thermodynamic properties of Tl9GdTe6 andTlGdTe2. Russian Journal of Physical Chemistry A.2018;92(11): 2111–2116. DOI: https://doi.org/10.1134/s003602441811015825. Mansimova S. H., Orujlu E. N., Sultanova S. G.,Babanly M. B. Thermodynamic properties of Pb6Sb6Se17.Kondensirovannye sredy i mezhfaznye granitsy =Condensed Matter and Interphases. 2017;19(4): 536–541. https://doi.org/10.17308/kcmf.2017.19/23426. Imamaliyeva S. Z., Gasanly T. M., MahmudovaM. A. Thermodynamic properties of GdTe compound.Physics. 2017;22: 19–21. Available at: http://physics.gov.az/Dom/2017/AJP_Fizika_04_2017_en.pdf27. Imamaliyeva S. Z., Musayeva S. S., Babanly D. M.,Jafarov Y. I., Tagiyev D. B., Babanly M. B. Determinationof the thermodynamic functions of bismuthchalcoiodides by EMF method with morpholiniumformate as electrolyte. Thermochim. Acta. 2019; 679:178319–17825. DOI: https://doi.org/10.1016/j.tca.2019.17831928. Baza dannykh termicheskikh konstant veshchestv.Elektronnaya versiya pod. red. V. S. Yungmana. 2006[Database of thermal constants of substances.Electronic version V. S. Yungman (ed.). 2006]. Availableat: http://www.chem.msu.ru/cgi-bin/tkv.pl?show=welcome.html/welcome.html
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Majumdar, Tushar Kanti, Moumita Khatua, Paromita Mazumdar, and Sayantan Mukherjee. "Effect of immediate and delayed finishing and polishing procedure on Streptococcal mutans adhesion and micro-hardness of composite resin surface: An in-vitro study." International Dental Journal of Student's Research 10, no. 1 (March 15, 2022): 5–10. http://dx.doi.org/10.18231/j.idjsr.2022.002.
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Proper finishing and polishing have become the indispensable step in clinical restorative dentistry due to increased aesthetic demands. There are several polishing systems containing fine particle size abrasives. The adhesion of bacterial plaque to restoration depends on the surface properties and composition of materials. In literature, surface roughness after polishing is well documented, but the timing, i.e., immediate or delayed polishing affecting the bacterial adherence and microhardness on the composite needs research. As the Streptococcus mutans has a major role in primary and secondary caries, so in this light, this study is conducted to investigate the best timing of polishing affecting the bacterial adhesion and microhardness of composite resin.: To evaluate the Streptococcal mutans adhesion and microhardness of composite resin after polishing them, immediately and after 24 hours of curing.: Sixty specimens were made from composite resin Filtek Z 350 XT (3M ESPE) of 6mm diameter and 4mm height, was cured by placing a Mylar strip and divided into 3 groups- Group 1 the control group with only MYLAR-STRIP, Group 2- Polishing system SOF-LEX (3M ESPE Dental products St. Paul, MN,USA.) Group 3- Polishing with SUPER-SNAP (Shofu Inc., Kyoto, Japan). Group 2 and 3 were further divided into two subgroups according to the polishing time- immediate and delayed. The Streptococcal mutans adhesion for each group was measured by colony forming units and compared. The mean log of CFU/mL present in the biofilm was also calculated. The results of bacterial adherence was analysed by three-way ANOVA (analysis of variance) (p<0.01) and the ANOVA two-way of variance was used for checking microhardness (p<0.01). A p value <0.01 was considered to indicate a statistically significant for both bacterial adhesion and hardness. Polishing after 24 hours of curing showed less bacterial adherence on the composite surface, regardless of the polishing treatment performed(p<0.01). Polishing with SOF-LEX(Group-2) had the lower bacterial adherence than SUPER-SNAP (Group-3), Control group (Mylar matrix strip) promoted the lowest bacterial adhesion on the surface composites. Micro hardness of composite was lowest in Mylar matrix group. Immediate polishing procedure showed lower microhardness values as compared to polishing that was delayed for 24hours for both polishing groups. SOF-LEX system can be used for chairside polishing of composite restorations in clinic and delayed finishing and polishing of composite shows better surface microhardness values.
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Muhammad Apandi, Nur Hidayah, Fauzan Ahmad, Siti Nur Fatin Zuikafly, Mohd Haniff Ibrahim, and Sulaiman Wadi Harun. "Bismuth (III) Telluride (Bi2Te3) topological insulator embed in PVA as passive Q-switcher at 2 micron region." Photonics Letters of Poland 8, no. 4 (December 31, 2016): 101. http://dx.doi.org/10.4302/plp.2016.4.04.
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We demonstrate a passive Q-switched at 2 um region by integrating Bismuth (III) Telluride (Bi2/Te3) embedded in Polyvinyl Alcohol (PVA). Bi2Te3 was embedded in PVA by solution casting approach to develop a Bi2/Te3-PVA film and integrated in the laser cavity with ring configuration to generate pulse laser. The experimental works show that the proposed passive saturable absorber operates at input pump power ranges from 637 mW to 784 mW with central wavelength of 1957.6 nm. We observed the tunable repetition rate from 12.6 kHz to 26.1 kHz with the shortest pulse width of 2.22 us. The laser produces maximum instantaneous output peak power and pulse energy of 0.42 W and 0.94 uJ, respectively. Full Text: PDF ReferencesC. Zhao, H. Zhang, X. Qi, Y. Chen, Z. Wang, S. Wen, and D. Tang, "Ultra-short pulse generation by a topological insulator based saturable absorber", Appl. Phys. Lett. 101, 211106 (2012). CrossRef Z. C. Luo, M. Liu, H. Liu, X.-W. Zheng, A.-P. Luo, C.-J. Zhao, H. Zhang, S. C. Wen, and W.-C. Xu, "2GHz passively harmonic mode-locked fiber laser by a microfiber-based topological insulator saturable absorber", Opt. Lett. 38, 5212 (2013). CrossRef J. Lee, J. Koo, Y. M. Jhon, and J. H. Lee, "A femtosecond pulse erbium fiber laser incorporating a saturable absorber based on bulk-structured Bi2Te3 topological insulator", Opt. Express 22, 6165 (2014). CrossRef M. Jung, J. Lee, J. Koo, J. Park, Y. W. Song, K. Lee, S. Lee, and J. H. Lee, "A femtosecond pulse fiber laser at 1935 nm using a bulk-structured Bi2Te3 topological insulator", Opt. Express 22, 7865(2014). CrossRef Y. H. Lin, C. Y. Yang, S.-F. Lin, W. H. Tseng, Q. Bao, C. I. Wu, and G.R. Lin, "Soliton compression of the erbium-doped fiber laser weakly started mode-locking by nanoscale p-type Bi2Te3 topological insulator particles", Laser Phys. Lett. 11, 055107(2014). CrossRef J. Lee et al., "All-fiberized, passively Q-switched 1.06 ?m laser using a bulk-structured Bi2Te3 topological insulator", Journal of Optics 16, 085203(2014). CrossRef Y. Chen, et al., "Large Energy, Wavelength Widely Tunable, Topological Insulator Q-Switched Erbium-Doped Fiber Laser", IEEE Journal of Selected Topics in Quantum Electronics 20, 315(2014). CrossRef M. Wu et al., "Nanosecond Q -Switched Erbium-Doped Fiber Laser With Wide Pulse-Repetition-Rate Range Based on Topological Insulator", IEEE Journal of Quantum Electronics 50, 393(2014). CrossRef J. Lee et al., "Dry Etched Waveguide Laser Diode on GeOI", IEEE Journal of Selected Topics in Quantum Electronics 21, 31(2015). CrossRef J. Li et al., "3-?m mid-infrared pulse generation using topological insulator as the saturable absorber ", Optics Letters 40, 3659(2015). CrossRef Z. Luo et al., "Topological-Insulator Passively Q-Switched Double-Clad Fiber Laser at 2 ?m Wavelength", IEEE J. Sel. Topics Quantum Electron 20, 0902708 (2014). CrossRef M. C. Paul, A. Dhar, S. Das, A. A. Latiff,M. T. Ahmad,and S. W. Harun, "Enhanced Erbium?Zirconia?Yttria?Aluminum Co-Doped Fiber Amplifier" IEEE Photonics Journal 7, 7100408 (2015). CrossRef H. Liu et al., "Femtosecond pulse generation from a topological insulator mode-locked fiber laser", Optics Express 22, 6868 (2014). CrossRef Z. Sun, T. Hasan, and A. C. Ferrari, "Ultrafast lasers mode-locked by nanotubes and graphene", Physica E 44, 1082(2012). CrossRef J. Lee, M. Jung, J. Koo, C. Chi, and J. Lee, "Dry Etched Waveguide Laser Diode on GeOI", IEEE Journal of Selected Topics in Quantum Electronics 21, 0900206 (2015). CrossRef H. Ahmad, A. Z. Zulkifli, K. Thambiratnam, and S. W. Harun, "2.0-?m Q-Switched Thulium-Doped Fiber Laser With Graphene Oxide Saturable Absorber", IEEE Photonics Journal5, 1501108(2013). CrossRef
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Martín-Sanz, A., J. L. Palomo, M. Pérez de la Vega, and C. Caminero. "First Report of Bacterial Blight Caused by Pseudomonas viridiflava on Pea in Spain." Plant Disease 94, no. 1 (January 2010): 128. http://dx.doi.org/10.1094/pdis-94-1-0128a.
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Because production of dry peas (Pisum sativum L.) is increasing in Spain, disease surveys were carried out from 2004 to 2006 in Castilla y Leon, the largest pea-producing region. In May of 2004, a leaf and stem blight caused an estimated 25% loss in yield in pea (cv. Messire) fields in El Cerrato (Palencia). Bacteria were isolated on King's B medium from 10 symptomatic plants from different fields (3). Thirty gram-negative isolates produced fluorescent, yellowish mucoid colonies. All isolates showed oxidative glucose metabolism on Hugh-Leifson medium and were levan and oxidase negative, potato soft rot positive, arginine dihydrolase negative, and tobacco hypersensitive positive. They also hydrolyzed esculine and gelatine. These results were different than those expected by Pseudomonas syringae pv. pisi and P. syringae pv. syringae (3). API 50 CH tests (bioMerieux, Marcy l'Etoile, France) revealed that all the isolates used the following carbon sources: glycerol, erythritol, l-arabinose, ribose, d-xylose, galactose, d-glucose, d-fructose, d-manose, inositol, manitol, sorbitol, d-raffinose, d-fucose, and d-arabitol. This nutritional profile is identical with that of P. viridiflava strain CFBP 6730, originally from pea plants in France. Therefore, these isolates were tentatively identified as P. viridiflava (2). Since a preliminary test demonstrated that 9 of the 30 isolates were pathogenic on pea plants, pathogenic isolates P44, P45, and P46 were selected arbitrarily for further tests. These three isolates plus strains HRI-W 1704 (P. syringae pv. pisi type race 6) and CFBP 1769 (P. syringae pv. syringae) were inoculated onto 10 pea seedlings (cv. Messire) each in two identical trials, following a described protocol (1). Seedlings inoculated with sterile distilled water were used as controls. After 10 days of incubation in a growth chamber at 22°C and 80% relative humidity, severe rotting and collapse similar to symptoms observed in fields appeared on pea seedlings inoculated with isolates P44, P45, and P46, while water-soaked leaf spots and necrotic symptoms were caused by P. syringae pv. pisi and P. pv. syringae. No symptoms were observed on plants inoculated with sterile water. Isolates recovered from symptomatic stems showed the same morphological and biochemical features of the original isolates. Sequences of 1,399 bp long from the three isolates (GenBank Accession Nos. GQ398128, GQ398129, and GQ398130) were 100% identical to P. viridiflava 16S rDNA database reference sequences. To our knowledge, this is the first report of P. viridiflava causing a disease of pea in Spain. The disease has been reported in New Zealand (4) and France (2). References: (1) E. M. Elvira-Recuenco et al. Eur. J. Plant Pathol. 109:555, 2003. (2) C. Grondeau et al. Plant Pathol. 41:495, 1992 (3) N. W. Schaad et al., eds. Laboratory Guide for the Identification of Plant Pathogenic Bacteria. 3rd ed. The American Phytopathological Society, St. Paul, MN, 2001. (4) J. D. Taylor et al. N. Z. J. Agric. Res. 5:432, 1972.
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Ostroverkh, Anna Serhiivna, Janik Scharf, Aristide Da Rosa, Markus Kübler, Vladislav Gridin, Sandeep Yadav, Jörg J. Schneider, and Ulrike I. Kramm. "Structural Aspects of Materials in Optimization of Fuel Cell Electrodes." ECS Meeting Abstracts MA2022-02, no. 39 (October 9, 2022): 2517. http://dx.doi.org/10.1149/ma2022-02392517mtgabs.
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Today's energy problems, caused by the irrational consumption of fossil fuels and, as a result, terrible environmental consequences, require the global population to quickly introduce clean energy sources. Electrochemical power sources, which include the fuel cell, provide the technological basis for electrical energy production. While proton exchange membrane fuel cells (PEMFC) rely on platinum based catalysts, obtaining stable and earth abundant catalytic materials for the oxygen reduction reaction (ORR) is an important step towards large scale integration. Our work focusses on FeNC noble-metal free catalysts in PEMFC conditions. The reaction conditions are much more complex in comparison to half cells, as transport processes and e.g. carbon oxidation affect the performance data. Thus, it turns out to be extremely difficult to determine the most important factors affecting the catalytic activity and stability of the material and to optimize the structure of the membrane-electrode assembly as several factors are overlaying each other: For example, the pyrolysis temperature affects the surface area, degree of graphitization and iron-related composition as well as extent of surface functional groups [1]. The metal loading, pyrolysis temperature and a use of possible precursor templates effects the structure, surface area as well as ORR activity and selectivity of catalysts [2], [3]. In our recent work, it was shown that in contrast to the electrochemical characteristics observed in rotating disc electrode (RDE) measurements, the best performing catalyst was prepared at the highest investigated temperature for both FC activity and stability [1]. In contrast, the dwell time had only a limited impact at low pyrolysis temperature, whereas a variation from 30 min to 90 min gave significant destruction of molecular FeNx moieties for the high temperature pyrolysis. [1] To gain further insights on the effect of preparation parameters on FC performance and in specific stability, we coupled a quadrupole mas-spectrometer to the cathode exhaust to follow possible release of CO2 depending on the applied conditions. The data are interpreted together with the structural characterization of the materials. We will discuss how the dwell time and pyrolysis temperature effected on morphology changes of the catalyst and to what extent this impacts the FC activity and short-term stability. Acknowledgements A.O. would like to thank you the TU Darmstadt for the Future talent scholarship, UIK gratefully acknowledges financial support by the BMBF young research group StRedO (03XP0092), and we thank Y. Ostroverkh, and Z. L. Müller, for the consultation and assistance with the fuel cell setup. [1] J. Scharf, M. Kübler, V. Gridin, W.D.Z. Wallace, L. Ni, S.D. Paul, U.I. Kramm, Relation between half-cell and fuel cell activity and stability of FeNC catalysts for the oxygen reduction reaction, (2022) SusMat, accepted (doi: 10.1002/sus2.84). [2] P.Theis, W.D. Z. Wallace, L. Ni, M. Kübler, A. Schlander, R. W. Stark, N. Weidler, M, Gallei, U. I. Kramm. Systematic study of precursor effects on structure and oxygen reaction activity of FeNC catalysts, (2021) Philos. Trans. Royal Soc. A PHILOS T R SOC A, (doi: 10.6084/m9.figshare.c.5506708). [3] P. Boldrin, D. Malko, A. Mehmood, U. I. Kramm, S. Wagner, S. Paul, N. Weidler, A. Kucernak. Deactivation, reactivation and super-activation of Fe-N/C oxygen reduction electrocatalysts: Gas sorption, physical and electrochemical investigation using NO and O2., (2021) Appl. Catal. B, Vol. 292, 120169, (doi: 10.1016/j.apcatb.2021.120169).
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Pérusse, Louis, Gregory Collier, Jacques Gagnon, Arthur S. Leon, D. C. Rao, James S. Skinner, Jack H. Wilmore, André Nadeau, Paul Z. Zimmet, and Claude Bouchard. "Acute and chronic effects of exercise on leptin levels in humans." Journal of Applied Physiology 83, no. 1 (July 1, 1997): 5–10. http://dx.doi.org/10.1152/jappl.1997.83.1.5.
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Pérusse, Louis, Gregory Collier, Jacques Gagnon, Arthur S. Leon, D. C. Rao, James S. Skinner, Jack H. Wilmore, André Nadeau, Paul Z. Zimmet, and Claude Bouchard. Acute and chronic effects of exercise on leptin levels in humans. J. Appl. Physiol. 83(1): 5–10, 1997.—The acute (single bout of exercise) and chronic (exercise training) effects of exercise on plasma leptin were investigated in 97 sedentary adult men ( n = 51) and women ( n = 46) participating in the HERITAGE Family Study. Exercise training consisted of a standardized 20-wk endurance training program performed in the laboratory on a computer-controlled cycle ergometer. Maximal oxygen uptake, body composition assessed by hydrostatic weighing, and fasting insulin level were also measured before and after training. Pre- and posttraining blood samples were obtained before and after completion of a maximal exercise test on the cycle ergometer. Exercise training resulted in significant changes in maximal oxygen uptake (increase in both genders) and body compostion (reduction of fat mass in men and increase in fat-free mass in women). There were considerable interindividual differences in the leptin response to acute and chronic effects of exercise, some individuals showing either increase or reduction in leptin, others showing almost no change. On average, leptin levels were not acutely affected by exercise. After endurance training was completed, leptin levels decreased significantly in men (from 4.6 to 3.9 ng/ml; P = 0.004) but not in women. However, after the training-induced changes in body fat mass were accounted for, the effects of exercise training were no longer significant. Most of the variation observed in leptin levels after acute exercise or endurance training appears to be within the confidence intervals of the leptin assay. We conclude that there are no meaningful acute or chronic effects of exercise, independent of the amount of body fat, on leptin levels in humans.
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Vettraino, A. M., S. Franceschini, and A. Vannini. "First Report of Buxus rotundifolia Root and Collar Rot Caused by Phytophthora citrophthora in Italy." Plant Disease 94, no. 2 (February 2010): 272. http://dx.doi.org/10.1094/pdis-94-2-0272a.
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Boxwood (Buxus spp.) includes several species of popular ornamental shrubs used in traditional and contemporary gardening. In March of 2008, a gradual and irreversible decline was observed on 6-year-old Buxus rotundifolia plants in a garden in central Italy. Of 150 boxwood plants, 70% were symptomatic, and among them, approximately 25% were completely wilted. Aboveground symptoms included stunting, necrotic bark lesions at the base of the stem, reduced growth, and leaf chlorosis. Leaves at first appeared light green, then turned yellow, bronze, or straw colored. Foliar symptoms were restricted to a few branches or extended to the whole crown. Immunological field tests (Pocket Diagnostic, CSL Diagnostics, Milan, Italy) on necrotic rootlets and bark tissues suggested the risk of the presence of Phytophthora spp. One species was consistently isolated on PARHP (2) from necrotic tissues of three symptomatic plants. Recovered isolates were heterothallic and produced aerial mycelium. Star-like compact growth was also observed on potato dextrose agar. Cultures on carrot agar submerged in saline solution (2) developed papillate, noncaducous, and sympodially branched sporangia of different shapes ranging from ovoid to obturbinate. Sporangia were 37.5 to 65.0 × 22.5 to 35.0 μm (average 49.0 × 31.0 μm); L/W ratio from 1.1 to 2.1 (average 1.6). On the basis of morphological features, these isolates belong to P. citrophthora (R.E. Sm. & E.H. Sm.) Leonian (2). The identity was confirmed by sequencing of the internal transcribed spacer region of the rDNA (NCBI Accession No. FJ874794). Inoculum for two isolates of P. citrophthora (3BO and 4BO) was produced for pathogenicity testing on 100 g of autoclaved millet grains moistened with 70 ml of V8 juice. Two, 2-liter aliquots of potting media were each amended with the infested grains (1:20 vol/vol) and five 3-year-old plants of B. rotundifolia per isolate were transplanted into the media. Plants were maintained in a growth chamber at 18 to 22°C, with relative humidity of 80%, and a 12-h photoperiod. Sterile millet grains were used to inoculate five boxwood plants for the control. After 2 months, control plants remained healthy while inoculated plants displayed root necroses and foliar symptoms similar to those observed in the field. The pathogen, consistently reisolated from roots of infected plants, reduced the root weight by an average of 25%. Root rot of boxwood plants is reported to be caused by P. citricola in Poland (4), P. parasitica in Virginia (3), and P. citrophthora in North Carolina (1). To our knowledge, this is the first report of P. citrophthora on B. rotundifolia in Europe. References: (1) Z. G. Abad et al. Plant Dis. 78:830, 1994. (2) D. C. Erwin and O. K. Ribeiro. Page 562 in: Phytophthora Diseases Worldwide. The American Phytopathological Society. St. Paul, MN, 1996. (3) M. A. Hansen. Plant Dis. Fact Sheets. 450-614W, 2000. (4) L. B. Orlikowski. J. Plant Prot. Res. 46:163, 2006.
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Vettraino, A. M., L. Flamini, L. Pizzichini, A. Prodi, P. Nipoti, A. Vannini, and R. Lagnese. "First Report of Root and Collar Rot by Phytophthora cryptogea on Sweet Cherry in Italy." Plant Disease 92, no. 1 (January 2008): 177. http://dx.doi.org/10.1094/pdis-92-1-0177a.
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Sweet cherry (Prunus avium L.) cultivation has increased in Italy and ≈30,000 ha are now in production. In the spring of 2006, a disease survey was conducted in orchards of central Italy. Decline symptoms of Prunus avium ‘Durone’ grafted on wild rootstocks of Prunus avium consisted of reduced tree vigor, yellowing of leaves, and development of root and collar rot. A reddish brown discoloration of the inner bark and wood was observed on symptomatic trees. Symptoms were recorded in three cherry orchards seasonally submitted to soil saturation conditions. In one orchard, symptoms were observed on approximately 30% of 170 surveyed trees. A Phytophthora species was consistently isolated on PARPH-V8 medium (2) from collar lesions of five cherry trees over nine trees randomly chosen among symptomatic trees in the three orchards. Colonies (20) were isolated and all appeared fluffy on potato dextrose agar and did not grow at 35°C. The morphological characteristics fit the descriptions of Phytophthora cryptogea Pethybr. & Lafferty (1). Sequence analysis of the internal transcribed spacers region of isolates shared 100% homology with P. cryptogea (GenBank Accession Nos. EF418948.1, EF418943.1, and EF153671.1). Pathogenicity of two P. cryptogea isolates (AN1 and AN2, Accession Nos. EF661576 and EF661577, respectively) was tested by soil infestation in a growth chamber at 22°C using 15 1-year-old rooted seedlings of wild rootstock of Prunus avium for each isolate. Noninoculated seedlings (15) were used as negative controls. The inoculum was produced by growing isolates on autoclaved millet grains moistened with V8 juice for 4 weeks. Each plant was inoculated with 30 cm3 of inoculum per liter of soil. Each seedling was randomly assigned to isolates AN1, AN2, or the noninoculated control and arranged in a complete random design. All plants were flooded for 24 h every 2 weeks for 8 weeks. At the end of the experiment, all inoculated seedlings showed crown wilting and root rot. Control plants showed no symptoms. Percentage of necrotic lateral roots expressed as dry weight (±SE) was 19.9 ± 0.6, 17.5 ± 0.2, and 4.4 ± 0.5, respectively, for seedlings inoculated with isolates AN1, AN2, and controls (analysis of variance F = 7.48, P < 0.01). Values of inoculated seedlings were significantly different from the control plants with the Tukey Post-Hoc test. No difference in virulence was observed between the two isolates. P. cryptogea was always reisolated from the roots of inoculated plants. Although pathogenicity of P. cryptogea on sweet cherry has been reported in the United States and other European countries (3,4), to our knowledge, this is the first record of P. cryptogea on sweet cherry orchards in Italy. The presence of P. cryptogea in cherry orchards is of significant concern because of its aggressiveness to this host and woody hosts such as apple, apricot, peach, walnut, and kiwi. References: (1) D. C Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996. (2) A. J. Ferguson and S. N. Jeffers. Plant Dis. 83:1129, 1999. (3) T. Tomidis and T. Sotiropoulos. N. Z. J. Crop Hortic. Sci. 31:355, 2003. (4) W. F. Wilcox and S. M. Mircetich. Phytopathology 75:1451, 1985.
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Faedda, R., S. O. Cacciola, A. Pane, P. Martini, M. Odasso, and G. Magnano di San Lio. "First Report of Phytophthora taxon niederhauserii Causing Root and Stem Rot of Mimosa in Italy." Plant Disease 97, no. 5 (May 2013): 688. http://dx.doi.org/10.1094/pdis-09-12-0889-pdn.
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Mimosa [Acacia dealbata Link, syn. Acacia decurrens (Wendl. F.) Wild. var. dealbata (Link) F. Muell., Fabaceae] is an evergreen shrub native to southeastern Australia that is cultivated as an ornamental plant in warm temperate regions of the world. In spring 2010, in a commercial nursery in Liguria (northern Italy), 6- to 10-month-old potted plants of A. dealbata showed symptoms of sudden collapse, defoliation, and wilt associated with root and basal stem rot. An abundant gum exudate oozed from the basal stem. A Phytophthora species was consistently isolated from roots and stem on BNPRAH selective medium (4). On V8 agar (V8A), axenic cultures obtained by single hyphal transfers formed stellate to radiate colonies with aerial mycelium whereas on potato dextrose agar (PDA) the colonies grew more slowly than on V8A and showed stoloniform mycelium and irregular margins. Minimum and maximum growth temperatures on PDA were 10 and 35°C, with the optimum at 30°C. In water, all isolates produced catenulate or single fusiform hyphal swellings and ellipsoid, nonpapillate, persistent sporangia. Dimensions of sporangia were 46.1 to 65.4 × 23.1 to 30.8 μm (mean l/b ratio 2.1). All isolates were A1 mating type and produced spherical oogonia with amphyginous antheridia when paired with A2 mating type of P. drechsleri Tucker on V8A plus β-sytosterol (4). Internal transcribed spacer (ITS) regions of rDNA of the representative Phytophthora isolate IMI 500394 from A. dealbata were amplified and sequenced in both directions with primers ITS6/ITS4. The consensus sequence (GenBank Accession No. JF900371) was 99% similar to sequences of several isolates identified as Phytophthora taxon niederhauserii Z.G. Abad and J.A. Abad (e.g., GQ848201 and EU244850). Pathogenicity tests were performed on 1-year-old potted plants of A. dealbata with isolate IMI 500394. Twenty plants were transplanted into pots (12-cm-diameter) filled with soil infested (4% v/v) with the inoculum of IMI500394 produced on kernel seeds. Plants were kept in a greenhouse with natural light at 25 ± 2°C and watered to field capacity weekly. All inoculated plants showed symptoms of wilt, leaf chlorosis, and basal stem rot within 3 to 4 weeks. Twenty control plants transplanted in autoclaved soil mix remained healthy. P. taxon niederhauserii was reisolated solely from inoculated plants, thus fulfilling Koch's postulates. Since 2003, this pathogen has been found on bottlebrush and rock rose grown in a nursery in Sicily (southern Italy), as well as on Banksia in a nursery in Liguria (2,3). To our knowledge, this is the first report of P. taxon niederhauserii on A. dealbata. P. taxon niederhauserii, recently described as P. niederhauserii sp. nov. (1), is a polyphagous pathogen that was originally reported on arborvitae and ivy in North Carolina in 2001. References: (1) Z. G. Abad et al. Mycologia (in press), 2013. (2) S. O. Cacciola et al. Plant Dis. 93:1075, 2009. (3) S. O. Cacciola et al. Plant Dis. 93:1216, 2009. (4) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996.
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Mills, S. J., A. R. Kampf, A. M. McDonald, G. Favreau, and P. J. Chiappero. "Forêtite, a new secondary arsenate mineral from the Cap Garonne mine, France." Mineralogical Magazine 76, no. 3 (June 2012): 769–75. http://dx.doi.org/10.1180/minmag.2012.076.3.24.
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AbstractForêtite, ideally Cu2Al2(AsO4)(OH,O,H2O)6, is a new secondary arsenate mineral from the Cap Garonne mine, Var, France (IMA2011-100). It has also been identified at the Salsigne gold mine, Languedoc-Roussillon, France. Although it was identified as a potentially new mineral in 1993, a formal description has only been possible as a result of a new find in a chamber called Annex S located near the entrance of the Cap Garonne mine. Forêtite occurs as pale sky blue to aqua aggregates, up to ∼0.1 mm across, made up of minute plates no more than 20 μm in length. It has a very pale blue streak. Individual crystals have a vitreous lustre and are transparent, whereas clusters appear translucent. The calculated density is 3.286 g cm–3. The crystals are brittle, with an irregular fracture and have a hardness of ∼3–4 on Moh's scale. Forêtite is found in direct association with bariopharmacoalumite, cyanotrichite, parnauite, chalcophyllite and mansfieldite in an Al-rich assemblage which is presumed to have formed under acidic conditions. It is biaxial; the average refractive index measured in white light on aggregates of forêtite crystals is 1.620(5). The empirical formula (based on 10 oxygen atoms per formula unit) is Cu1.94(Al1.96Fe0.04)Σ2.00(As0.84S0.09Si0.04)Σ0.97O10H5.19. Raman spectroscopy confirms the presence of OH and H2O in the structure. Forêtite is triclinic, space group P, with a = 6.969(9), b = 7.676(9), c = 8.591(11) Å, α = 82.01(9), β = 71.68(8), γ = 102.68(8)°, V = 415(1) Å3 and Z = 2. The five strongest lines in the X-ray powder diffraction pattern [d in A ˚ , (I), (hkl)] are as follows: 7.307, (100), (010, 00); 3.141, (24), (200, 00); 2.818, (24), (20, 20); 4.519, (23), (111); 2.343, (22), (11). The mineral is named in honour of Dr Jean-Paul Forêt, who co-founded the project that turned the Cap Garonne mine into a protected site and museum.
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Cacciola, S. O., S. Scibetta, P. Martini, C. Rizza, and A. Pane. "Phytophthora taxon niederhauserii, a New Root and Crown Rot Pathogen of Banksia spp. in Italy." Plant Disease 93, no. 11 (November 2009): 1216. http://dx.doi.org/10.1094/pdis-93-11-1216c.
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In the last 10 years, various species of Banksia (family Proteaceae) endemic to Australia have been introduced into Italy where cultivation as flower plants is expanding. In the spring of 2003, a decline associated with root and basal stem rot of 2- to 3-year-old plants of Banksia speciosa R. Br., B. baxteri R. Br., and B. prionotes Lindl. grown in the ground was observed in a commercial nursery in Liguria (northern Italy). Aboveground symptoms included leaf chlorosis and wilt. Plants collapsed within 1 to 2 weeks after the appearance of leaf symptoms. A Phytophthora species was consistently isolated from roots and basal stem on BNPRAH selective medium (3). On V8 juice agar (V8A), axenic cultures obtained by single hyphal transfers formed stellate to radiate colonies with aerial mycelium; on potato dextrose agar (PDA). the colonies showed stoloniform mycelium. Minimum and maximum growth temperatures on PDA and V8A were between 5 and 10°C and 38 and 40°C, respectively, with the optimum at 30°C on PDA (mean radial growth rate of 10 isolates ranged between 9.3 and 10.2 mm per day) and 25 to 30°C on V8A (14 mm per day). In saline solution and soil extract, all isolates produced catenulate hyphal swellings and ellipsoid, nonpapillate, persistent sporangia. Sporangia in saline solution varied from 47 to 70 × 30 to 44 μm (mean l/b ratio of 1.5). All isolates were A1 mating type and produced oogonia with amphyginous antheridia when paired with A2 mating type of P. drechsleri Tucker on V8A plus β-sytosterol (3). The electrophoretic patterns of total mycelial proteins and two isozymes (esterase and malate dehydrogenase) (2) of all isolates from Banksia plants were identical, but distinct from the patterns of isolates of other Phytophthora species, including P. drechsleri, P. megasperma sensu stricto, and P. sojae. Internal transcribed spacer (ITS) regions of rDNA were amplified with primers ITS4/ITS6 and sequences of two isolates, IMI 393960 from B. speciosa and 466/03 from B. baxteri (GenBank Nos. FJ648808 and FJ648809), were 100% identical to sequences of isolates identified as Phytophthora taxon niederhauserii Z. G. Abad and J. A. Abad (GenBank Nos. AY550916, AM942765, and EU244850). Pathogenicity tests were performed on 1-year-old potted plants of B. speciosa with isolates IMI 393960 and 466/03. Twenty plants per each isolate were transplanted into 12-cm-diameter pots containing infested soil prepared by mixing steam-sterilized sandy loam soil with 1% of inoculum produced on autoclaved wheat kernels. Twenty control plants were grown in autoclaved soil mix. Plants were kept in the greenhouse with natural light at 25 ± 2°C and watered to field capacity weekly. All Banksia plants transplanted in infested soil showed symptoms of wilt, leaf chlorosis, and basal stem rot within 2 to 3 weeks. Noninoculated plants remained healthy. P. taxon niederhauserii was reisolated solely from inoculated plants. P. taxon niederhauserii has been reported recently from Banksia spp. in Australia (1), but to our knowledge this is the first report from Italy. P. taxon niederhauserii may represent a threat to the cultivation of many ornamentals including Cystus spp., English ivy, and laurel (4). References: (1) T. I. Burgess et al. Plant Dis. 93:215, 2009. (2) S. O. Cacciola et al. EPPO Bull. 20:47, 1990. (3) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996. (4) E. Moralejo et al. Plant Pathol, 58:100, 2009.
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Martini, P., A. Pane, F. Raudino, A. Chimento, S. Scibetta, and S. O. Cacciola. "First Report of Phytophthora tentaculata Causing Root and Stem Rot of Oregano in Italy." Plant Disease 93, no. 8 (August 2009): 843. http://dx.doi.org/10.1094/pdis-93-8-0843b.
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Oregano (Origanum vulgare L.; Lamiaceae) is cultivated for culinary and medicinal purposes and as an ornamental. In October of 2007, 1- to 2-year-old potted plants of oregano showed symptoms of decline associated with root and basal stem rot in a nursery in Liguria (northern Italy) that produces 1 million to 1.5 million potted aromatic plants per year. Aboveground symptoms included leaf russeting and chlorosis, wilt, defoliation and dieback of twigs, browning of the basal stem, and subsequent collapse of the entire plant. Approximately 80% of the plants died within 30 days after the appearance of the first symptoms on the canopy. Approximately 20% of a stock of 30,000 oregano plants was affected. Stocks of other aromatic species, such as mint, lavender, rosemary, and sage, appeared healthy. A Phytophthora species was consistently isolated from symptomatic stems and roots of oregano plants on BNPRAH selective medium (2). Ten pure cultures were obtained by single-hypha transfers, and the species was identified as Phytophthora tentaculata Kröber & Marwitz by morphological criteria and sequencing of the internal transcribed spacer (ITS) region of rDNA using the ITS 4 and ITS 6 universal primers for DNA amplification. Isolates from oregano formed stoloniferous colonies with arachnoid mycelium on potato dextrose agar and had a growth rate of 2 to 3 mm per day at 24°C with optimum, minimum, and maximum temperatures of 24, 8, and 34°C, respectively. Sporangia formed in soil extract solution and were papillate and spherical or ovoid to obpyriform with a length/breadth ratio of 1.3:1. Few sporangia were caducous and all had a short pedicel (<5 μm). Hyphal swellings and chlamydospores were produced in sterile distilled water and corn meal agar, respectively. All isolates were homothallic and produced globose terminal oogonia (mean diameter of 34 μm) with one or occasionally two paragynous, monoclinous, or diclinous antheridia. Amphigynous antheridia were also observed. The sequence of the ITS region of the rDNA (GenBank No. FJ872545) of an isolate from oregano (IMI 395782) showed 99% similarity with sequences of two reference isolates of P. tentaculata (Accession Nos. AF266775 and AY881001). To test for pathogenicity, the exposed root crowns of 10 6-month-old potted plants of oregano were drench inoculated with 10 ml of a suspension of 2 × 104 zoospores/ml of isolate IMI 395782. Sterile water was pipetted onto the roots of 10 control plants. All plants were maintained in 100% humidity at 22 to 24°C in a greenhouse under natural light and watered once a week. Within 3 weeks after inoculation, all inoculated plants developed symptoms identical to those observed in the nursery and died within 30 to 40 days after the appearance of the first symptoms. Control plants remained healthy. P. tentaculata was reisolated solely from symptomatic plants. P. tentaculata has been reported previously on several herbaceous ornamental plants (1,3). However, to our knowledge, this is the first report of this species on O. vulgare. Root and basal stem rot caused by P. tentaculata is the most serious soilborne disease of oregano reported in Italy so far. References: (1) G. Cristinzio et al. Inf. Fitopatol. 2:28, 2006. (2) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996. (3) H. Kröber and R. Marwitz. Z. Pflanzenkr. Pflanzenschutz 100:250, 1993.
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Stauder, S., and P. M. Peloso. "POS1125 DUAL ENERGY CT HAS PROGNOSTIC VALUE IN GOUT BEYOND STANDARD CLINICAL MEASURES: A BEST EVIDENCE SYNTHESIS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 841.2–842. http://dx.doi.org/10.1136/annrheumdis-2021-eular.872.
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Background:Dual Energy CT Scan (DECT) can detect monosodium urate crystal deposits in multiple tissues. EULAR gout guidelines (Richette, 2020) recognized the value of DECT in making a clinical diagnosis when joint aspiration is difficult. DECT shows crystal deposits in almost 50% of gout patients without tophi (Dalbeth, 2017). Tophi are known to predict all-cause and cardiovascular mortality (Vincent 2017, Perez-Ruiz 2013) and it is plausible that DECT could as well. A prognostic measure should be reliable and valid. DECT validity would be evident for death, disability and distress.Objectives:This study used a best evidence synthesis approach to synthesize the evidence for DECT as a prognostic measure in gout.Methods:PUBMED and EMBASE were searched from initiation to December 2019; keywords (Dual Energy Computed Tomography OR DECT, gout, tophaceous gout, chronic gout, monosodium urate crystals OR monosodium urate burden OR tophi OR monosodium urate volume OR flares OR pain OR distress OR death OR disability OR function). Human studies in English were considered. Titles, abstracts and full articles were reviewed. A manual search of secondary sources was conducted. Key gaps identified were considered throughout 2020 when reviewing emerging articles and presentations. Data extraction was conducted by both authors; data presented represents consensus.Results:Of 344 articles, 81 titles/abstracts met screening inclusion criteria (24%) in the 2019 search; review of the full manuscript led to 41 articles selected (51%). Additionally, 3 key papers and 2 ACR 2020 presentations were identified through 2020. DECT is highly reliable with inter-class correlation coefficients >0.9. DECT has content validity. Dalbeth (2015) showed DECT and X-Rays findings correlated in tophaceous patients, r=0.70, p<0.001. Hand function correlates with DECT burden, with r2=0.59, p=0.024 (Dalbeth 2007). Dalbeth (2017) showed DECT associated with greater flares at 3 and 12 months (p<0.01) in 152 patients. Pascart (2018) confirmed that subjects with flares had nearly doubled DECT feet volumes (0.9 vs 2.1 cm3, p=0.05) versus those not flaring. Dalbeth (2017) showed abnormal DECT scans occurred in 47% of patients with normal uric acid (<6.0 mg/dL) without palpable tophi and in 90% with elevated uric acid and palpable tophi. DECT is very sensitive to change (Araujo 2015) with 95% volume reduction in 152 patients on pegloticase treated up to 12 months. Three studies show DECT is correlated to cardiovascular risk factor prevalence (Pascart 2020, Gamala 2018, Lee 2017). Marty-Ané reported that DECT volume predicts mortality (Marty-Ané ACR 2020). Limited evidence from 3 studies suggests that the minimum important volume for DECT is 1.0 cm3 at feet and ankles, including Pascart 2020.Conclusion:DECT imaging is highly reliable, has evidence for content validity and is highly sensitive to change. DECT appears to predict future gout flares, cardiovascular risk factor prevalence and mortality. Minimum important DECT volume approximates 1.0 cm3. DECT requires further study but appears to be a relevant outcome for clinical trials and staging gout patients.References:AuthorsJournal, Volume, IssueYearAraujo, E. G., Bayat, S., et al.RMD Open2015Dalbeth, N., Nicolaou, S., et al.Ann Rheum Dis, 77(3)2017Dalbeth, N., Aati, O., et al.Ann Rheum Dis, 74(6)2015Dalbeth, N., Collis, J., et al.Rheumatology, 46(12)2007Gamala, M., Linn-Rasker, S. P., et al.Clinical Rheumatol, 37(7)2018Lee, K., Ryu, S., et al.Clinical Rheumatol, 372017Marty-Ané, A., Norberciak, L., et al.Arthritis Rheumatol 72 (supp 10) [abstract #0954] ACR 2020.2020Pascart, T., Ramon, A., et al.J Clin Med, 9(5)2020Pascart, T., Capon, B., et al.Arthritis Res and Therapy, 20(1)2018Perez-Ruiz, F., Martínez-Indart, L., et al.Ann Rheum Dis, 73(1)2013Richette, P., Doherty, M., et al.Ann Rheum Dis, 79(1)2020Vincent, Z., Gamble, G., et al.J Rheumatol, 44 (3)2017Disclosure of Interests:Sally Stauder: None declared, Paul M. Peloso Shareholder of: Horizon Therapeutics plc, Employee of: Horizon Therapeutics plc.
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Alippi, A. M., and A. C. López. "First Report of Leaf Spot Disease of Maize Caused by Pantoea ananatis in Argentina." Plant Disease 94, no. 4 (April 2010): 487. http://dx.doi.org/10.1094/pdis-94-4-0487a.
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From 2007 to 2008, an uncharacterized disease of maize (Zea mays L.) was observed in commercial fields of Laguna Blanca, Formosa, Argentina and from different fields of Santa Fe and Catamarca provinces of Argentina. Symptoms included light-colored necrotic streaks on leaves and tan or white irregular blotches that sometimes were surrounded by reddish purple-to-dark brown margins. Severity of symptoms varied greatly from one field to another. Abundant bacterial streaming was observed from lesions when examined at ×150. Gram-negative, facultatively anaerobic bacteria were consistently isolated from lesions. These formed light yellow-to-orange, glistening, convex colonies on yeast dextrose calcium carbonate agar incubated at 30°C. Ten isolates from ten different symptomatic plants were selected for further study. All isolates were motile, induced a hypersensitive response in tobacco plants, and were oxidase negative. Colonies developed at 37°C. Physiological and biochemical characterization with the API 20E test strips and database (bioMerieux, Buenos Aires, Argentina) showed that the strains belonged to the genus Pantoea. All strains were positive for β-galactosidase, utilized citrate and tartrate, and produced acid from d-glucose, d-mannitol, d-melibiose, l-arabinose, sucrose, meso-inositol, glycerol, d-sorbitol, and amygdalin. All were negative for arginine dihydrolase, lysine decarboxylase, ornithine decarboxylase, tryptophane deaminase, H2S production, urease, and reduction of nitrate to nitrite. Variable results were obtained for indole, gelatinase, and l-rhamnose. Their identity was confirmed by sequencing the 16S rRNA gene strain F327 (GenBank Accession No. GU068363). A BlastN search of GenBank revealed 99% nt identity with strains LMG 20103 (AF364847.1), LMG 20105 (AF364845.1), and LMG 2665 (FJ611815.1) of Pantoea ananatis. Pathogenicity was verified on Z. mays (EM 6079 HX, Dow Morgan) by injection-infiltration of bacterial suspensions at 105 CFU/ml. Controls were infiltrated with sterile distilled water. Plants were kept at 26 ± 3°C in a greenhouse. Symptoms were first detected 15 to 17 days after inoculation and then lesions expanded to resemble natural infections within 30 days. Bacteria were reisolated and the original and reisolated strains were compared by using repetitive sequence-based (rep)-PCR with ERIC primers (1) and fingerprints of the reisolated strains were identical to those of the original strains, thereby fulfilling Koch's postulates. No lesions were observed on controls. Known strains of P. stewartii from the United States (SW2, DC400, DC441, and DC283) were also tested for comparison. On the basis of sequencing data, pathogenicity, and physiological tests, the pathogen was identified as P. ananatis (4). To our knowledge, this is the first report of P. ananatis causing a disease of maize in Argentina, although a similar disease has been reported in Brazil (2) and Mexico (3). References: (1) F. J. Louws et al. Appl. Environ. Microbiol. 60:2286, 1994. (2) L. D. Paccola-Meirelles et al. J. Phytopathol. 149:275, 2001. (3) R. Pérez-y-Terrón et al. Australas. Plant Dis. Notes 4:96, 2009. (4) N. W. Schaad et al., eds. Laboratory Guide for Identification of Plant Pathogenic Bacteria. 3rd ed. The American Phytopathological Society, St. Paul, MN, 2001.
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KITLV, Redactie. "Book Reviews." New West Indian Guide / Nieuwe West-Indische Gids 69, no. 1-2 (January 1, 1995): 143–216. http://dx.doi.org/10.1163/13822373-90002650.
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-Sidney W. Mintz, Paget Henry ,C.L.R. James' Caribbean. Durham: Duke University Press, 1992. xvi + 287 pp., Paul Buhle (eds)-Allison Blakely, Jan M. van der Linde, Over Noach met zijn zonen: De Cham-ideologie en de leugens tegen Cham tot vandaag. Utrecht: Interuniversitair Instituut voor Missiologie en Oecumenica, 1993. 160 pp.-Helen I. Safa, Edna Acosta-Belén ,Researching women in Latin America and the Caribbean. Boulder CO: Westview, 1993. x + 201 pp., Christine E. Bose (eds)-Helen I. Safa, Janet H. Momsen, Women & change in the Caribbean: A Pan-Caribbean Perspective. Bloomington: Indiana University Press; Kingston: Ian Randle, 1993. x + 308 pp.-Paget Henry, Janet Higbie, Eugenia: The Caribbean's Iron Lady. London: Macmillan, 1993. 298 pp.-Kathleen E. McLuskie, Moira Ferguson, Subject to others: British women writers and Colonial Slavery 1670-1834. New York: Routledge, 1992. xii + 465 pp.-Samuel Martínez, Senaida Jansen ,Género, trabajo y etnia en los bateyes dominicanos. Santo Domingo: Instituto Tecnológico de Santo Domingo, Programa de Estudios se la Mujer, 1991. 195 pp., Cecilia Millán (eds)-Michiel Baud, Roberto Cassá, Movimiento obrero y lucha socialista en la República Dominicana (desde los orígenes hasta 1960). Santo Domingo: Fundación Cultural Dominicana, 1990. 620 pp.-Paul Farmer, Robert Lawless, Haiti's Bad Press. Rochester VT: Schenkman Press, 1992. xxvii + 261 pp.-Bill Maurer, Karen Fog Olwig, Global culture, Island identity: Continuity and change in the Afro-Caribbean Community of Nevis. Chur, Switzerland: Harwood Academic Publishers, 1993. xi + 239 pp.-Viranjini Munasinghe, Kevin A. Yelvington, Trinidad Ethnicity. Knoxville: University of Tennesee Press, 1993. vii + 296 pp.-Kevin K. Birth, Christine Ho, Salt-water Trinnies: Afro-Trinidadian Immigrant Networks and Non-Assimilation in Los Angeles. New York: AMS Press, 1991. xvi + 237 pp.-Steven Gregory, Andrés Isidoro Pérez y Mena, Speaking with the dead: Development of Afro-Latin Religion among Puerto Ricans in the United States. A study into the Interpenetration of civilizations in the New World. New York: AMS Press, 1991. xvi + 273 pp.-Frank Jan van Dijk, Mihlawhdh Faristzaddi, Itations of Jamaica and I Rastafari (The Second Itation, the Revelation). Miami: Judah Anbesa Ihntahnah-shinahl, 1991.-Derwin S. Munroe, Nelson W. Keith ,The Social Origins of Democratic Socialism in Jamaica. Philadelphia: Temple University Press, 1992. xxiv + 320 pp., Novella Z. Keith (eds)-Virginia Heyer Young, Errol Miller, Education for all: Caribbean Perspectives and Imperatives. Washington DC: Inter-American Development Bank, 1992. 267 pp.-Virginia R. Dominguez, Günter Böhm, Los sefardíes en los dominios holandeses de América del Sur y del Caribe, 1630-1750. Frankfurt: Vervuert, 1992. 243 pp.-Virginia R. Dominguez, Robert M. Levine, Tropical diaspora: The Jewish Experience in Cuba. Gainesville: University Press of Florida, 1993. xvii + 398 pp.-Aline Helg, John L. Offner, An unwanted war: The diplomacy of the United States and Spain over Cuba, 1895-1898. Chapel Hill: University of North Carolina Press, 1992. xii + 306 pp.-David J. Carroll, Eliana Cardoso ,Cuba after Communism. Cambridge MA: MIT Press, 1992. xiii + 148 pp., Ann Helwege (eds)-Antoni Kapcia, Ian Isadore Smart, Nicolás Guillén: Popular Poet of the Caribbean. Columbia: University of Missouri Press, 1990. 187 pp.-Sue N. Greene, Moira Ferguson, The Hart Sisters: Early African Caribbean Writers, Evangelicals, and Radicals. Lincoln: University of Nebraska Press, 1993. xi + 214 pp.-Michael Craton, James A. Lewis, The final campaign of the American revolution: Rise and fall of the Spanish Bahamas. Columbia: University of South Carolina Press, 1991. xi + 149 pp.-David Geggus, Clarence J. Munford, The black ordeal of slavery and slave trading in the French West Indies, 1625-1715. Lewiston NY: The Edwin Mellen Press, 1991. 3 vols. xxii + 1054 pp.-Paul E. Sigmund, Timothy P. Wickham-Crowley, Guerillas and Revolution in Latin America: A comparative Study of Insurgents and Regimes since 1956. Princeton: Princeton University Press, 1992. xx + 424 pp.-Robert E. Millette, Patrick A.M. Emmanuel, Elections and Party Systems in the Commonwealth Caribbean, 1944-1991. St. Michael, Barbados: Caribbean Development Research Services, 1992. viii + 111 pp.-Robert E. Millette, Donald C. Peters, The Democratic System in the Eastern Caribbean. Westport CT: Greenwood Press, 1992. xiv + 242 pp.-Pedro A. Cabán, Arnold H. Liebowitz, Defining status: A comprehensive analysis of United States Territorial Relations. Boston & Dordrecht: Martinus Nijhoff, 1989. xxii + 757 pp.-John O. Stewart, Stuart H. Surlin ,Mass media and the Caribbean. New York: Gordon & Breach, 1990. xviii + 471 pp., Walter C. Soderlund (eds)-William J. Meltzer, Antonio V. Menéndez Alarcón, Power and television in Latin America: The Dominican Case. Westport CT: Praeger, 1992. 199 pp.
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Gao, J., N. Nan, B. H. Lu, Y. N. Liu, X. Y. Wu, and W. Y. Xia. "First Report of Bacterial Soft Rot of Milk Thistle (Silybum marianum) Caused by Pectobacterium carotovorum subsp. carotovorum in Jilin Province of China." Plant Disease 98, no. 8 (August 2014): 1152. http://dx.doi.org/10.1094/pdis-02-14-0137-pdn.
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Milk thistle (Silybum marianum) is an annual or biannual plant of the Asteraceae family that produces the hepaprotectant silymarin. In 2012, almost all milk thistle grown in the medicinal herbal garden of Jilin Agricultural University (Changchun, Jilin Province, China) exhibited symptoms of a previously undetected soft rot disease. Initial symptoms on stems appeared as tan, semitransparent, and water-soaked, then became sunken. The rotted lesions expanded rapidly and inner stem tissues were rotten with a foul smell. Eventually, the whole plant became black, then collapsed and died. Economic losses were significant as the seed crop was almost completely lost. Nine bacterial strains were isolated from tissues on nutrient agar (NA) medium after 36 h incubation at 28°C (1). Colonies of the nine strains were round, shiny, grayish white, and convex on NA medium. All strains were gram-negative, non-fluorescent, facultatively anaerobic, motile with two to four peritrichous flagella (observed by electron transmission microscope), positive for catalase and potato rot, but negative for oxidase and lecithinase. Strains grew at 37°C and in yeast salts broth medium containing 5% NaCl. They also liquefied gelatin. Strains were also negative for starch hydrolysis, malonate utilization, gas production from glucose, and indole. Results were variable for the Voges-Proskauer test and production of H2S from cysteine. The strains utilized esculin, fructose, D-galactose, D-glucose, inositol, lactose, D-mannose, D-mannitol, melibiose, rhamnose, salicin, trehalose, D-xylose, and cellobiose as carbon sources, but not melezitose, α-CH3-D-gluconate, sorbitol, or starch. Glycerol and maltose were only weakly utilized. Species identity was confirmed by molecular analysis of one of the strains, SMG-2. HPLC indicated a DNA GC content of 50.55%. The 16S rDNA sequence (KC207898) of SMG-2 showed 99% sequence identity to that of a Pectobacterium carotovorum subsp. carotovorum strain (DQ333384) and the sequence of the 16S-23S rDNA spacer region (KJ415377) was 95% similar to that of another known strain of P. carotovorum subsp. carotovorum (AF232684). Based on biochemical and physiological characteristics (2), as well as 16S rDNA gene analysis, the strains were identified as P. carotovorum subsp. carotovorum. Pathogenicity of the nine strains was evaluated by depositing a bacterial suspension (108 CFU/ml) on wounded stems (made with a disinfected razor blade) of 3-month-old milk thistle plants. Three plants were inoculated with each strain and three plants were treated with sterilized water as negative controls. Inoculated plants were covered with plastic bags for 24 h in a greenhouse at 28 to 30°C. After 48 h, the plants inoculated with bacteria showed similar symptoms as the naturally infected plants, while control plants remained symptomless. The symptoms observed on inoculated stems were rotten and sunken tissues. Bacteria were re-isolated from the inoculated plants and confirmed to be identical to the original strains based on 16S rDNA sequence analysis. To our knowledge, this is the first report of P. carotovorum subsp. carotovorum causing bacterial soft rot of milk thistle in Changchun, Jilin Province, China. References: (1) Z. D. Fang. Research Method of Phytopathology. China Agricultural Press (In Chinese), 1998. (2) N. W. Schaad et al., eds. Laboratory Guide for Identification of Plant Pathogenic Bacteria, 3rd ed. American Phytopathological Society, St. Paul, MN, 2001.
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Reinhardt, Jan. "Annegret Bollée / Dominique Fattier / Ingrid Neumann-Holzschuh (edd.), Dictionnaire étymologique des créoles français d’Amérique [DECA], Rédaction Annegret Bollée/Katharina Kernbichl/Ulrike Scholz/Evelyn Wiesinger, avec le concours de Jean-Paul Chauveau, Première partie: Mots d’origine française, vol. 1: A-D, vol. 2: E-O, vol. 3: P-Z, Hamburg, Buske, 2018, XXXIII + 539, XIII + 525, XIII + 505 p." Zeitschrift für romanische Philologie 138, no. 3 (October 1, 2022): 964–67. http://dx.doi.org/10.1515/zrp-2022-0045.
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Utomo, Muhajir, Irwan Sukri Banuwa, Henrie Buchari, Yunita Anggraini, and Berthiria. "Long-term Tillage and Nitrogen Fertilization Effects on Soil Properties and Crop Yields." JOURNAL OF TROPICAL SOILS 18, no. 2 (June 12, 2013): 131. http://dx.doi.org/10.5400/jts.2013.v18i2.131-139.
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The impact of agricultural intensification on soil degradation now is occurring in tropical countries. The objective of this study was to determine the effect of long-term tillage and N fertilization on soil properties and crop yields in corn-soybean rotation. This long-term study which initiated since 1987 was carried out on a Typic Fragiudult soil at Politeknik Negeri Lampung, Sumatra (105o13’45.5"-105o13’48.0"E, 05o21’19.6"-05o21’19.7"S) in 2010 and 2011. A factorial experiment was arranged in a randomized block design with four replications. The first factor was tillage system namely intensive tillage (IT) and conservation tillage (CT) which consist of minimum tillage (MT) and no-tillage (NT); while the second factor was N fertilization with rates of 0, 100 and 200 kg N ha-1 applied for corn, and 0, 25, and 50 kg N ha-1 for soybean. The results showed that bulk density and soil strength at upper layer after 24 years of cropping were similar among treatments, but the soil strength under IT at 50-60 cm depth was 28.2% higher (p<0.05) than NT. Soil moisture and temperature under CT at 0-5 cm depth were respectively 38.1% and 4.5% higher (p<0.05) than IT. High N rate decreased soil pH at 0-20 cm depth as much as 10%, but increased total soil N at 0-5 cm depth as much as 19% (p<0.05). At 0-10 cm depth, MT with no N had highest exchangeable K, while IT with medium N rate had the lowest (p<0.05). At 0-5 cm depth, MT with no N had highest exchangeable Ca, but it had the lowest (p<0.05) if combined with higher N rate. Microbial biomass C throughout the growing season for NT was consistently highest and it was 14.4% higher (p<0.05) than IT. Compared to IT, Ap horizon of CT after 24 years of cropping was deeper, with larger soil structure and more abundance macro pores. Soybean and corn yields for long-term CT were 64.3% and 31.8% higher (p<0.05) than IT, respectively. Corn yield for long-term N with rate of 100 kg N ha-1 was 36.4% higher (p<0.05) than with no N.Keywords: Conservation tillage, crop yields, N fertilization, soil properties[How to Cite: Utomo M, IS Banuwa, H Buchari, Y Anggraini and Berthiria. 2013.Long-term Tillage and Nitrogen Fertilization Effects on Soil Properties and Crop Yields. J Trop Soils 18 (2): 131-139. Doi: 10.5400/jts.2013.18.2.131][Permalink/DOI: www.dx.doi.org/10.5400/jts.2013.18.2.131] REFERENCESAl-Kaisi and X Yin. 2005. Tillage and crop residue effects on soil carbon dioxide emission in corn- soybean rotation. J Environ Qual 34: 437-445. Pub Med. Barak P, BO Jobe, AR Krueger, LA Peterson and DA Laird. 1997. Effects of long-term soilacidification due to nitrogen inputs in Wisconsin. Plant Soil 197: 61-69.Blake GR and KH Hartge. 1986. Bulk density. In: A Klute (ed). Methods of Soil Analysis. ASA and SSSA. Madison, Wisconsin, USA, pp. 363-375.Blanco-Canqui H and R Lal. 2008. No-till and soil-profile carbon sequestration: an on farm assessment. Soil Sci Soc Am J 72: 693-701. Blanco-Canqui H, LR Stone and PW Stahlman. 2010. Soil response to long-term cropping systems on an Argiustoll in the Central Great Plains. Soil Sci Soc Am J 74: 602-611.Blevins RL, MS Smith, GW Thomas and WW Frye. 1983. Influence of conservation tillage on soil properties. J Soil Water Conserv 38: 301-305.Blevins RL, GW Thomas and PL Cornelius. 1977 Influence of no-tillage and nitrogen fertilization on certain soil properties after 5 years of continuous corn. Agron J 69: 383-386.Blevins, RL and WF Frye, 1993. Conservation tillage: an ecological approach to soil management. Adv Agron 51: 34-77.Brady NC and RR Weil. 2008. The nature and properties of soils. Pearson Prentice Hall. Fourteenth Edition. New Jersey, 965 p.Brito-Vega, H, D Espinosa-Victoria, C Fragoso, D Mendoza, N De la Cruz Landaro and A Aldares-Chavez. 2009. Soil organic particle and presence of earthworm under different tillage systems. J Biol Sci 9: 180-183.Derpch, R 1998. Historical review of no-tilage cultivation of crops. JIRCAS Working Rep. JAPAN Int Res Ctr for Agric Sciences, Ibaraki, Japan 13: 1-18. Diaz-Zorita, M., JH Grove, L Murdock, J Herbeck and E Perfect. 2004. Soil structural disturbance effects on crop yields and soil properties in a no-till production system. Agron J 96: 1651-1659.Dickey EC, PJ Jasa and RD Grisso. 1994. Long-term tillage effect on grain yield and soil properties in a soybean/grain sorghum Rotation. J Prod Agric 7: 465 - 470.Edwards WM, LD, Norton, CE, Redmond. 1988. Characterizing macro pores that affect infiltration into non tilled soil. Soil Sci Soc Am J 52: 483-487.Fernandez RO, PG Fernandez, JVG Cervera and FP Torres. 2007 Soil properties and crop yields after 21 years of direct drilling trials in southern Spain. Soil Till Res 94: 47-54.Fengyun Z, W Pute, Z Xining and C Xuefeng. 2011. The effects of no-tillage practice on soil physical properties. Afr J Biotech 10: 17645-17650. Havlin, JL, JD Beaton, SM Tisdale and WL Nelson. 2005. Soil Fertility and Fertilizer: an Introduction to Nutrient Management. Pearson Prantice Hall. Sevent Edition. Upper Saddle River, New Jersey, 515 p.Karlen DL, NC Wollenhaupt, DC Erbach, EC Berry, JB Swan, NS Eash and JL Jordahl. 1994. Crop residue effects on soil quality following 10-years of no-till corn. Soil Till Res 31: 149-167.Kumar A and DS Yadav. 2005. Effect of zero and minimum tillage in conjunction with nitrogen management in wheat (Triticum aestivum ) after rice (Oryza sativa.). Indian J Agron 50 (1): 54-57.Lal R. 1989. Conservation tillage for sustainable agriculture: tropics versus temperate environment. Adv Agron 42: 85-197.Lal R. 1997. Residue management, conservation tillage and soil restoration for mitigating greenhouse effect by CO2 enrichment. Soil Till Res 43: 81-107.Lal R. 2007. Soil science in a changing climate. CSA New 52: 1-9.Mallory J J, RH Mohtar, GC Heathman, DG Schulze and E Braudeau. 2011. Evaluating the effect of tillage on soil structural properties using the pedostructure concept. Geoderma 163: 141-149. doi:10.1016/ j.geoderma. 2011.01.018. 9p.Paustian K, HP Collins and EA Paul. 1997. Management control on soil carbon. In: EA Paul, ET Elliot, K Paustian and CV Cole (eds). Soil Organic Matter in Temperate Agro-ecosystems: Long-term Experiment in North America. CRC Press, pp. 15-50.Rasmussen, KJ. 1999. Impact of ploughless soil tillage on yield and soil quality: A Scandinavian review. Soil Till Res 53: 3-14.Quintero M. 2009. Effects of conservation tillage in soil carbon sequestration and net revenues of potato-based rotations in the Colombian Andes. [Thesis], University of Florida, USA. SAS [Statistical Analysis System] Institute. 2003. The SAS system for windows. Release 9.1. SASInst Inc, Cary, NC.Singh A and J Kaur. 2012. Impact of conservation tillage on soil properties in rice-wheat cropping system. Agric Sci Res J 2: 30-41.Six, J, SD Frey, RK Thiet and KM Batten. 2006. Bacterial and fungal contributions to carbon sequestration in agroecosystems. Soil Sci Soc Am J 70: 555-569.Smith JL and HP Collins. 2007. Management of organisms and their processes in soils. In: EA Paul (ed). Soil Microbiology, Ecology and Biochemistry. Third Edition. Academic Press, Burlington, USA, 532 p.Stockfisch N, T Forstreuter, W Ehlers. 1999. Ploughing effects on soil organic matter after twenty years of conservation tillage in Lower Saxony, Germany. Soil Till Res 52: 91-101.Tarkalson, DD, GW Hergertb and KG Cassmanc. 2006. Long-term effects of tillage on soil chemical properties and grain yields of a dryland winter wheat-sorghum/corn-fallow rotation in the great plains. Agron J 26: 26-33. Thomas GA, RC Dalal, J Standley. 2007. No-till effect on organic matter, pH, cation exchange capacity and nutrient distribution in a Luvisol in the semi-arid subtropics. Soil Till Res 94: 295-304.Utomo M, H Suprapto and Sunyoto. 1989. Influence of tillage and nitrogen fertilization on soil nitrogen, decomposition of alang-alang (Imperata cylindrica) and corn production of alang-alang land. In: J van der Heide (ed.). Nutrient management for food crop production in tropical farming systems. Institute for Soil Fertility (IB), pp. 367-373.Utomo M. 2004. Olah tanah konservasi untuk budidaya jagung berkelanjutan. Prosiding Seminar Nasional IX Budidaya Pertanian Olah Tanah Konservasi. Gorontalo, 6-7 Oktober, 2004, pp. 18-35 (in Indonesian).Utomo M, A Niswati, Dermiyati, M R Wati, AF Raguan and S Syarif. 2010. Earthworm and soil carbon sequestration after twenty one years of continuous no-tillage corn-legume rotation in Indonesia. JIFS 7: 51-58.Utomo M, H Buchari, IS Banuwa, LK Fernando and R Saleh. 2012. Carbon storage and carbon dioxide emission as influenced by long-term conservation tillage and nitrogen fertilization in corn-soybean rotation. J Trop Soil 17: 75-84.Wang W, RC Dalal and PW Moody. 2001. Evaluation of the microwave irradiation method for measuring soil microbial biomass. Soil Sci Soc Am J 65: 1696-1703.Wright AL and FM Hons. 2004. Soil aggregation and carbon and nitrogen storage under soybean cropping sequences. Soil Sci Soc Am J 68: 507-513. Zibilske LM, JM Bradford and JR Smart. 2002. Conservation tillage induced change in organic carbon, total nitrogen and available phosphorus in a semi-arid alkaline subtropical soil. Soil Till Res 66: 153-163.
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KITLV, Redactie. "Bookreview." New West Indian Guide / Nieuwe West-Indische Gids 79, no. 1-2 (January 1, 2005): 103–70. http://dx.doi.org/10.1163/22134360-90002504.
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Marcus Wood; Slavery, Empathy, and Pornography (Lynn M. Festa)Michèle Praeger; The Imaginary Caribbean and Caribbean Imaginary (Celia Britton)Charles V. Carnegie; Postnationalism Prefigured: Caribbean Borderlands (John Collins)Mervyn C. Alleyne; The Construction and Representation of Race and Ethnicity in the Caribbean and the World (Charles V. Carnegy)Jerry Gershenhorn; Melville J. Herskovits and the Racial Politics of Knowledge (Richard Price)Sally Cooper Coole; Ruth Landes: A Life in Anthropology (Olivia Maria Gomes Da Cunha)Maureen Warner Lewis; Central Africa in the Caribbean: Transcending Time, Transforming Cultures (Robert W. Slenes)Gert Oostindie (ed.); Facing up to the Past: Perspectives on the Commemoration of Slavery from Africa, the Americas and Europe (Gad Heuman)Gert Oostindie, Inge Klinkers; Decolonising the Caribbean: Dutch Policies in a Comparative Perspective (Paul Sutton)Kirk Peter Meigho; Politics in a ‘Half-Made Society’: Trinidad and Tobago, 1925-2001 (Douglas Midgett)Linden Lewis (ed.); The Culture of Gender and Sexuality in the Caribbean (David A.B. Murray)Gertrude Aub-Buscher, Beverly Ormerod Noakes (eds.); The Francophone Caribbean Today: Literature, Language, Culture (Elizabeth Walcott-Hackshaw)Sally Lloyd-Evans, Robert B. Potter; Gender, Ethnicity and the Iinformal Sector in Trinidad (Katherine E. Browne)STeve Striffler, Mark Moberg (eds.); Banana Wars: Power, Production and History in the Americas (Peter Clegg)Johannes Postma, Victor Enthoven (eds.); Riches from Atlantic Commerce: Dutch Transatlantic Trade and Shipping, 1585-1817 (Gert J. Oostindie)Phil Davison; Volcano in Paradise: Death and Survival on the Caribbean Island of Montserrat (Bonham C. Richardson)Ernest Zebrowski jr; The Last Days of St. Pierre: The Volcanic Disaster that Claimed Thirty Thousand Lives (Bernard Moitt)Beverley A. Steele; Grenada: A History of Its People (Jay R. Mandle)Walter C. Soderlund (ed.); Mass Media and Foreign Policy: Post-Cold War Crises in the Caribbean (Jason Parker)Charlie Whitham; Bitter Rehearsal: British and American Planning for a Post-War West Indies (Jason Parker)Douglas V. Amstrong; Creole Transformation from Slavery to Freedom: Historical Archaeology of the East End Community, St. John, Virgin Islands (Karin Fog Olwig)H.U.E. Thoden van Velzen; Een koloniaal drama: De grote staking van de Marron vrachtvaarders, 1921 (Chris de Beet)Joseph F. Callo; Nelson in the Caribbean: The Hero Emerges, 1784-1787 (Carl E. Swanson)Jorge Duany; The Puerto Rican Nation on the Move: Identities on the Island and in the United States (Juan Flores)Raquel Z. Rivera; New York Ricans from the Hip Hop Zone (Halbert Barton)Alfonso J. García Osuna; The Cuban Filmography, 1897 through 2001 (Ann Marie Stock)Michael Aceto, Jeffrey P. Williams (eds.); Contact Englishes of the Eastern Caribbean (Geneviève Escure)In: New West Indian Guide / Nieuwe West-Indische Gids (NWIG) 79 (2005), no. 1 & 2
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KITLV, Redactie. "Bookreview." New West Indian Guide / Nieuwe West-Indische Gids 79, no. 1-2 (January 1, 2008): 103–70. http://dx.doi.org/10.1163/13822373-90002504.
Full textAbstract:
Marcus Wood; Slavery, Empathy, and Pornography (Lynn M. Festa)Michèle Praeger; The Imaginary Caribbean and Caribbean Imaginary (Celia Britton)Charles V. Carnegie; Postnationalism Prefigured: Caribbean Borderlands (John Collins)Mervyn C. Alleyne; The Construction and Representation of Race and Ethnicity in the Caribbean and the World (Charles V. Carnegy)Jerry Gershenhorn; Melville J. Herskovits and the Racial Politics of Knowledge (Richard Price)Sally Cooper Coole; Ruth Landes: A Life in Anthropology (Olivia Maria Gomes Da Cunha)Maureen Warner Lewis; Central Africa in the Caribbean: Transcending Time, Transforming Cultures (Robert W. Slenes)Gert Oostindie (ed.); Facing up to the Past: Perspectives on the Commemoration of Slavery from Africa, the Americas and Europe (Gad Heuman)Gert Oostindie, Inge Klinkers; Decolonising the Caribbean: Dutch Policies in a Comparative Perspective (Paul Sutton)Kirk Peter Meigho; Politics in a ‘Half-Made Society’: Trinidad and Tobago, 1925-2001 (Douglas Midgett)Linden Lewis (ed.); The Culture of Gender and Sexuality in the Caribbean (David A.B. Murray)Gertrude Aub-Buscher, Beverly Ormerod Noakes (eds.); The Francophone Caribbean Today: Literature, Language, Culture (Elizabeth Walcott-Hackshaw)Sally Lloyd-Evans, Robert B. Potter; Gender, Ethnicity and the Iinformal Sector in Trinidad (Katherine E. Browne)STeve Striffler, Mark Moberg (eds.); Banana Wars: Power, Production and History in the Americas (Peter Clegg)Johannes Postma, Victor Enthoven (eds.); Riches from Atlantic Commerce: Dutch Transatlantic Trade and Shipping, 1585-1817 (Gert J. Oostindie)Phil Davison; Volcano in Paradise: Death and Survival on the Caribbean Island of Montserrat (Bonham C. Richardson)Ernest Zebrowski jr; The Last Days of St. Pierre: The Volcanic Disaster that Claimed Thirty Thousand Lives (Bernard Moitt)Beverley A. Steele; Grenada: A History of Its People (Jay R. Mandle)Walter C. Soderlund (ed.); Mass Media and Foreign Policy: Post-Cold War Crises in the Caribbean (Jason Parker)Charlie Whitham; Bitter Rehearsal: British and American Planning for a Post-War West Indies (Jason Parker)Douglas V. Amstrong; Creole Transformation from Slavery to Freedom: Historical Archaeology of the East End Community, St. John, Virgin Islands (Karin Fog Olwig)H.U.E. Thoden van Velzen; Een koloniaal drama: De grote staking van de Marron vrachtvaarders, 1921 (Chris de Beet)Joseph F. Callo; Nelson in the Caribbean: The Hero Emerges, 1784-1787 (Carl E. Swanson)Jorge Duany; The Puerto Rican Nation on the Move: Identities on the Island and in the United States (Juan Flores)Raquel Z. Rivera; New York Ricans from the Hip Hop Zone (Halbert Barton)Alfonso J. García Osuna; The Cuban Filmography, 1897 through 2001 (Ann Marie Stock)Michael Aceto, Jeffrey P. Williams (eds.); Contact Englishes of the Eastern Caribbean (Geneviève Escure)In: New West Indian Guide / Nieuwe West-Indische Gids (NWIG) 79 (2005), no. 1 & 2
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Johnson, Amy J., Lisa L. Smith, Amy J. Wagner, Joshua Hessler, Joseph M. Flynn, Jeffrey A. Jones, Xiaoli Zhang, et al. "Dinaciclib (SCH727965) Is a Novel Cyclin Dependent Kinase Inhibitor That Promotes Selective Apoptosis In CLL Cells and Abrogates the Protective Effects of Microenvironment Cytokines." Blood 116, no. 21 (November 19, 2010): 971. http://dx.doi.org/10.1182/blood.v116.21.971.971.
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Abstract Abstract 971 The first generation cyclin dependent kinase (CDK) inhibitor flavopiridol has significant clinical activity in refractory CLL including those with del(17p13.1). These successes have prompted development of second generation molecules that lack the protein binding, off-target effects (i.e. GSK3-β inhibition), and complex enterohepatic circulation that exist with flavopiridol. Dinaciclib is a selective inhibitor of CDK 1, 2, 5 and 9 (IC50 of < 5nM) and lacks GSK3-β inhibition. Dinaciclib was selected as a lead CDK inhibitor candidate by an in vivo screen that identified it as having a favorable therapeutic index. Completed phase I studies in solid tumor cancer patients with dinaciclib have confirmed this favorable toxicity profile. We sought to explore the pre-clinical activity of dinaciclib in CLL to support its clinical development. Our studies demonstrate that dinaciclib promotes concentration-dependent apoptosis that is superior to flavopiridol following a clinically relevant 2-hour exposure (74.4% viable with 1μM flavopiridol compared to 26.7% viable with 1μM dinaciclib, p<0.0001). Additionally, dinaciclib, like flavopiridol, lacks cytotoxic effects on normal T-cells under these same conditions. Dinaciclib induced cytotoxicity was independent of IgVH mutational status and fludarabine refractoriness. Surprisingly, CLL cells from patients with del(17p13.1) were significantly more resistant than from patients with normal cytogenetics (68.2% viable versus 19.6%, p=0.0006) to dinaciclib induced cytotoxicity. This is in contrast to flavopiridol (54.1% viable versus 50.0%, p=0.2119) where this has not been seen. This finding is being investigated in the current phase 1 clinical trial of dinaciclib in CLL. Apoptosis induced by dinaciclib is caspase dependent, as co-incubation with the caspase inhibitor z-VAD-fmk rescued dinaciclib induced cytotoxicity. As seen with other CDK inhibitors, dinaciclib potently down-regulated Mcl-1 and Bcl-2 expression at a mRNA and protein level in CLL cells. Given the importance of microenvironment stimuli to CLL survival, we sought to determine how soluble and contact microenvironment effects influence dinaciclib cytotoxicity. T-cells and stromal cells promote CLL cell survival in part through the production of cytokines including CD40 ligand, BAFF, TNF-α, and IL-4. While CD40 ligand, BAFF, TNF-α, and IL-4 all protected CLL cells from spontaneous apoptosis, they did not significantly abrogate dinaciclib-mediated cytotoxicity. Consequently dinaciclib inhibited CD40 ligand induced up-regulation of Mcl-1 protein expression. The mechanism by which this protection is abrogated appears to involve down-regulation of the respective ligand receptor, as expression of each of these receptors was notably reduced at 2 hours in 1μM dinaciclib-treated CLL cells. CLL cells also derive protection from both spontaneous and drug-induced apoptosis by direct co-culture (and contact) with stromal cells. We therefore assessed the cytotoxic effect of dinaciclib on CLL patient cells when cultured in the presence of stromal cells. These studies surprisingly demonstrated loss of adhesion of stromal cells and abrogation of CLL cell protection. To avoid any direct effect of dinaciclib on the stromal cells, we then pre-treated CLL cells with 1μM dinaciclib for 2 hours, followed by washout and incubation on stromal cells. In these experiments, co-culture of CLL cells on stromal cells almost completely abrogated dinaciclib-mediated cytotoxicity. Similar findings were observed with fibronectin-coated plates. Together, these data indicate that stromal protection of CLL cells against dinaciclib is mediated either by cell-cell contact or by cytokines other than those tested. Collectively, these studies support the development of dinaciclib for the treatment of CLL, and also identify distinct microenvironment signals that may modulate response to this novel agent. Additionally, the differential response to del(17p13.1) CLL cells suggest distinct differences between dinaciclib and flavopiridol that are currently under investigation. This work was supported by the National Cancer Institute Leukemia SPORE P50-CA140158, The Leukemia and Lymphoma Society and The D. Warren Brown Foundation. AJJ is a Paul Calabresi Scholar. Disclosures: Jones: Glaxo Smith-Kline: Consultancy; Abbott: Research Funding. Bannerji:Merck & Co: Employment, Equity Ownership.
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Abed, Carolina Zuppo. "ENSINO DE ESCRITA LITERÁRIA NA UNIVERSIDADE: O PERCURSO BRASILEIRO." IPOTESI – REVISTA DE ESTUDOS LITERÁRIOS 25, no. 1 (December 30, 2021): 04–23. http://dx.doi.org/10.34019/1982-0836.2021.v25.36666.
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Este artigo recupera os argumentos centrais de alguns protagonistas da inclusão dos laboratórios de escrita nas universidades brasileiras, analisando suas bases teóricas e os ecos encontrados no percurso histórico de países em que a escrita criativa como área de conhecimento já se encontra consolidada. Demonstra como é possível rastrear a defesa pela inclusão da criação literária nas universidades brasileiras até o final do século XIX. Objetiva, também, contribuir para a organização do debate histórico sobre os cursos de escrita criativa no Brasil. Palavras-chave: Criação literária. Escrita criativa. Oficina literária. Ensino de literatura. História da literatura. REFERÊNCIAS ABED, Carolina Z. Presença da Escrita Criativa no Brasil. Revera – Escritos de Criação Literária, v. 6, 2021 [no prelo]. AMABILE, Luís Roberto. O fantasma, o elefante e o sótão: apontamentos sobre a escrita criativa na academia. Cenários, v. 1, n. 9, p. 53-61, 2014. AMABILE, Luís Roberto. Do que estamos falando quando falamos de escrita criativa. Criação & Crítica, n. 28, p. 132-149, dez 2020. AMABILE, Luis Roberto. Escrita criativa: a aventura começa. In: AMABILE, Luís Roberto; LINARDI, Fred & RICHINITTI, Gabriela (orgs.). Como tudo começou: a história e 35 histórias dos 35 anos da Oficina de Criação Literária da PUCRS. Porto Alegre: EDIPUCRS, 2020b. ALENCAR, José de. Sonhos d’ouro. Rio de Janeiro : B. L. Garnier, 1872. ANDRADE, Mário. Cartas a um jovem escritor: de Mário de Andrade a Fernando Sabino. Rio de Janeito: Record, 1982. ASSIS, Machado de. Obra completa de Machado de Assis. Rio de Janeiro: Nova Aguilar, v. III, 1994. BARBOSA, Amilcar B. Da leitura à escrita: a construção de um texto, a formação de um escritor. 2012. Tese (Doutorado em Letras) – Programa de Pós-Graduação em Letras, Pontifícia Universidade Católica do Rio Grande do Sul/Université Sorbonne Nouvelle, Porto Alegre/Paris, 2012. BRASIL, Luiz Antonio de Assis. A escrita criativa e a universidade. Letras de Hoje, Porto Alegre, v. 50, n. esp. (supl.) , p. s105-s109, dez. 2015a. BRASIL, Luiz Antonio de Assis. Escrita criativa – e reflexiva, ma non troopo. Scriptorium, v. 1, n. 1 jul-dez/2015b, p. 1-5. BRASIL, Luiz Antonio de Assis et. al. Percepções e perspectivas discentes nos cursos de pós-graduação em Escrita Criativa da PUCRS. Navegações, Porto Alegre, v. 10, n. 2, p. 149-155, 2017. COUTINHO, Eduardo. A contribuição de Afrânio Coutinho para os estudos literários no Brasil. In: FIGUEIREDO, Carmen Lúcia Negreiros de, et. al. (orgs.) Crítica e Literatura. Rio de Janeiro: De Letras, 2011, p. 185-196. DAWSON, Paul. Creative writing and the new humanities. Abingdon: Routledge, 2004. DONNELLY, Diane J. Establishing creative writing as an academic discipline. Bristol: Multilingual Matters, 2012. DOURADO, Autran. Uma poética de romance: matéria de carpintaria. Rio de Janeiro: Difel, 1976. EUROPEAN ASSOCIATION OF CREATIVE WRITING PROGRAMMES. Institutional members. Disponível em: https://eacwp.org/members/. Acesso em: 13 set. 2021. FORTUNATO, Márcia V. Autoria e aprendizagem da escrita. Tese (Doutorado em Educação) – Programa de pós-graduação em Educação - Área de concentração: linguagem e educação, Universidade de São Paulo, São Paulo, 2009. GERMANO, Tiago. Breve panorama da escrita criativa no nordeste. In: TENÓRIO, Patricia Gonçalves (org.). Sobre a escrita criativa II. Recife: Raio de Sol, 2018. p. 334-355. GOMEZ, Dimas. Oficineiros e suas oficinas: proseando pela Paulicéia. Amazon Digital Services: 2015. JORDAN-BAKER, Craig. The philosophy of creative writing. New Writing, v. 12, n. 2, p. 238-248, jul./dez. 2015. JUNQUEIRA, Maria Aparecida. Samir Curi Meserani. Coleção Sapientia – Grandes Mestres da PUC-SP. São Paulo: EDUC, 2017. MACVEAN, Kendall Elizabeth. Expansion and inclusion of creative writing: a course for academic writers. Monografia (Bachelor of Arts) – Appalachian State University. Orientadora: Elizabeth Carroll. Carolina do Norte, 2016. MANCELOS, João de. Uma nova abordagem interdisciplinar: da escrita criativa aos estudos crítico-criativos. Carnets: Revista Eletrônica De Estudos Franceses, p. 257-265, Outono/Inverno 2009. MANCELOS, João de. Um pórtico para a Escrita Criativa. Pontes & Vírgulas: Revista municipal de cultura. Ano 2, n. 5, p. 14-15, primavera de 2007. MCGURL, Mark. The program era: postwar fiction and the rise of creative writing. Cambridge (Massachussets) e Londres: Harvard University, 2009. MESERANI, Samir Curi. Quem conta um conto (v. 1-6). São Paulo: Atual, 1989. MEYERS, David Gershom. The elephants teach: creative writing since 1880. Chicago: University of Chicago, 1996 MINÉ, Elza (2003). Criatividade: Homenagem ao Prof. Samir Curi Meserani. Videoteca PUC-SP. PUC 1554: Parte I e II (gravação realizada em 25/08/1999). PEREZ, Marcelo Spalding & ASSIS BRASIL, Luiz Antonio. A escrita criativa nos cursos de Pós-Graduação. Revista do Programa de Pós-Graduação em Letras da Universidade de Passo Fundo, v. 14, n. 2, p. 207-220, maio/ago. 2018. POE, Edgar Allan. A filosofia da composição. Rio de Janeiro: 7 Letras, 2011. PUBLISHNEWS. Unisinos cria curso superior para escritores. Disponivel em: https://www.publishnews.com.br/materias/2006/05/18/21723-unisinos-cria-curso-superior-para-escritores. Acesso em: 16 set. 2021. POSTAY, Andrezza. Por que estudar escrita criativa. In: TENÓRIO, Patricia Gonçalves (org.). Sobre a escrita criativa II. Recife: Raio de Sol, 2018, p. 69-77. RODRIGUES, Flávio Luis Freire. Os recentes manuais de escrita criativa publicados no Brasil entre 2005 e 2019. Miguilim – Revista Eletrônica do Netlli, Crato, v. 9, n. 3, p. 661-679, set./dez. 2020. SAUNDERS, G. A Mini-Manifesto. In: HARBACH, C. (Ed.). MFA vs NYC: the Two Cultures of American Fiction. New York: Faber and Faber, 2014. p. 31-38. SIQUEIRA, Yan P. B. Oficina literária de escrita criativa. Dissertação (Mestrado em Letras) – Universidade Federal do Espírito Santo, Centro de Ciências Humanas e Naturais. Orientador: Paulo Roberto Sodré. Vitória, 2016. XAVIER, Leila Pinheiro. Formação para a escrita literária no ensino superior brasileiro. In: Seminário Interlinhas, 2014.1 (14 e 15 de agosto de 2014, Alagoinhas, BA) / Anais: Org. Gislene Alves da Silva, Luane Tamires dos Santos Martins e Sheila Rodrigues dos Santos; Universidade do Estado da Bahia – Programa de Pós-Graduação em Crítica Cultural. Alagoinhas: Fábrica de Letras, 2014. p. 153-162.
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MD Yusof, M. Y., J. Robinson, V. Davies, D. Wild, M. Morgan, J. Taylor, Y. El-Sherbiny, et al. "OP0190 COMPREHENSIVE GENETIC AND FUNCTIONAL ANALYSES OF Fc GAMMA RECEPTORS EXPLAIN RESPONSE TO RITUXIMAB THERAPY FOR AUTOIMMUNE RHEUMATIC DISEASES." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 126–27. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2615.
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BackgroundRituximab is widely used to treat rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) but clinical response varies. Efficacy is determined by the efficiency of depletion, which may depend on a variety of Fc gamma receptor (FcγR)-dependent mechanisms. Previous research was limited by complexity of the FCGR locus, not integrating copy number variation with functional SNP, and small sample size.ObjectivesThe study objectives were to assess the effect of the full range of FcγRs variants on depletion, clinical response and functional effect on NK-cell-mediated killing in two rheumatic diseases with a view to personalised B-cell depleting therapies.MethodsA prospective longitudinal cohort study was conducted in 873 patients [RA=611; SLE=262] from four cohorts (BSRBR-RA and BILAG-BR registries, Leeds RA and Leeds SLE Biologics). For RA, the outcome measures were 3C-DAS28CRP and 2C-DAS28CRP at 6 (+/-3) months post-rituximab (adjusted for baseline DAS28). For SLE, major clinical response (MCR) was defined as improvement of active BILAG-2004 domains to grade C/better at 6 months. B-cell depletion was evaluated by highly-sensitive flow cytometry. Qualitative and quantitative polymorphisms for five major FcγRs were measured using a commercial multiplex ligation-dependent probe amplification. Median NK cell FcγRIIIa expression (CD3-CD56+CD16+) and NK-cell degranulation (CD107a) in the presence of rituximab-coated Daudi/Raji B-cell lines were assessed using flow cytometry.ResultsIn RA, for FCGR3A, carriage of V allele (coefficient -0.25 (SE 0.11); p=0.02) and increased copies of V allele (-0.20 (0.09); p=0.02) were associated with greater 2C-DAS28 response. Irrespective of FCGR3A genotype, increased gene copies were associated with a better response. In SLE, 177/262 (67.6%) achieved BILAG response [MCR=34.4%; Partial=33.2%]. MCR was associated with increased copies of FCGR3A-158V allele, OR 1.64 (95% CI 1.12-2.41) and FCGR2C-ORF allele 1.93 (1.09-3.40). Of patients with B-cells data in the combined cohort, 236/413 (57%) achieved complete depletion post-rituximab. Only homozygosity for FCGR3A-158V and increased FCGR3A-158V copy number were associated with increased odds of complete depletion. Patients with complete depletion had higher NK cell FcγRIIIa expression at rituximab initiation than those with incomplete depletion (p=0.04) and this higher expression was associated with improved EULAR response in RA. Moreover, for FCGR3A, degranulation activity was increased in V allele carriers vs FF genotype in the combined cohort; p=0.02.ConclusionFcγRIIIa is the major low affinity FcγR and increased copies of the FCGR3A-158V allele, encoding the allotype with a higher affinity for IgG1, was associated with clinical and biological responses to rituximab in two autoimmune diseases. This was supported by functional data on NK cell-mediated cytotoxicity. In SLE, increased copies of the FCGR2C-ORF allele was also associated with improved response. Our findings indicate that enhancing FcγR-effector functions could improve the next generation of CD20-depleting therapies and genotyping could stratify patients for optimal treatment protocols.ReferencesNoneAcknowledgementsThis research was funded/supported by the joint funding from the Medical Research Council (MRC) and Versus Arthritis of MATURA (grant codes 36661 and MR/K015346/1). MASTERPLANS was funded by the MRC (grant code MR/M01665X/1). The Leeds Biologics Cohort was part funded by programme grants from Versus Arthritis (grant codes 18475 and 18387), the National Institute for Health Research (NIHR) Leeds Biomedical Research Centre (BRC) and Diagnostic Evaluation Co-operative and the Ann Wilks Charitable Foundation. The BILAG-BR has received funding support from Lupus UK, and unrestricted grants from Roche and GSK.The functional studies were in part supported through a NIHR/HEFCE Clinical Senior Lectureship and a Versus Arthritis Foundation Fellowship (grant code 19764) to AWM, the Wellcome Trust Institutional Strategic Support Fund to JIR and MYMY (204825/Z/16/Z), NIHR Doctoral Research Fellowship to MYMY (DRF-2014-07-155) and NIHR Clinician Scientist to EMV (CS-2013-13-032). . AWM, INB, JDI and PE were supported by NIHR Senior Investigator awards. Work in JDI’s laboratory is supported by the NIHR Newcastle BRC, the Research Into Inflammatory Arthritis Centre Versus Arthritis, and Rheuma Tolerance for Cure (European Union Innovative Medicines Initiative 2, grant number 777357). INB is funded by the NIHR Manchester BRC.This article/paper/report presents independent research funded/supported by the NIHR Leeds BRC and the NIHR Guy’s and St Thomas’ BRC. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.Disclosure of InterestsMd Yuzaiful Md Yusof: None declared, James Robinson: None declared, Vinny Davies: None declared, Dawn Wild: None declared, Michael Morgan: None declared, John Taylor: None declared, Yasser El-Sherbiny: None declared, David Morris: None declared, Lu Liu: None declared, Andrew Rawstron: None declared, Maya H Buch: None declared, Darren Plant: None declared, Heather Cordell: None declared, John Isaacs: None declared, Ian N. Bruce: None declared, Paul Emery Speakers bureau: Roche, Consultant of: Roche, Grant/research support from: Roche, Anne Barton: None declared, Timothy Vyse: None declared, Jennifer Barrett: None declared, Edward Vital Consultant of: Roche, Grant/research support from: Roche, Ann Morgan Speakers bureau: Roche/Chugai, Consultant of: GSK, Roche, Chugai, AstraZeneka, Regeneron, Sanofi, Vifor, Grant/research support from: Roche, Kiniksa Pharmaceuticals
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Allers, Eugene, Christer Allgulander, Sean Exner Baumann, Charles L. Bowden, P. Buckley, David J. Castle, Beatrix J. Coetzee, et al. "13th National Congress of the South African Society of Psychiatrists, 20-23 September 2004." South African Journal of Psychiatry 10, no. 3 (October 1, 2004): 17. http://dx.doi.org/10.4102/sajpsychiatry.v10i3.150.
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List of abstacts and authors:1. Integrating the art and science of psychiatryEugene Allers2. Chronic pain as a predictor of outcome in an inpatient Psychiatric populationEugene Allers and Gerhard Grundling3. Recent advances in social phobiaChrister Allgulander4. Clinical management of patients with anxiety disordersChrister Allgulander5. Do elephants suffer from Schizophrenia? (Or do the Schizophrenias represent a disorder of self consciousness?) A Southern African perspectiveSean Exner Baumann6. Long term maintenance treatment of Bipolar Disorder: Preventing relapseCharles L. Bowden7. Predictors of response to treatments for Bipolar DisorderCharles L. Bowden8. Aids/HIV knowledge and high risk behaviour: A Geo-graphical comparison in a schizophrenia populationP Buckley, S van Vuuren, L Koen, J E Muller, C Seller, H Lategan, D J H Niehaus9. Does Marijuana make you go mad?David J Castle10. Understanding and management of Treatment Resistant SchizophreniaDavid J Castle11. Workshop on research and publishingDavid J Castle12. From victim to victor: Without a self-help bookBeatrix Jacqueline Coetzee13. The evaluation of the Gender Dysphoric patientFranco Colin14. Dissociation: A South African modelA M Dikobe, C K Mataboge, L M Motlana, B F Sokudela, C Kruger15. Designated smoking rooms...and other "Secret sins" of psychiatry: Tobacco cessation approaches in the severely mentally illCharl Els16. Dual diagnosis: Implications for treatment and prognosisCharl Els17. Body weight, glucose metabolism and the new generation antipsychoticsRobin Emsley18. Neurological abnormalities in first episode Schizophrenia: Temporal stability and clinical and outcome correlatesRobin Emsley, H Jadri Turner, Piet P Oosthuizen, Jonathan Carr19. Mythology of depressive illnesses among AfricansSenathi Fisha20. Substance use and High school dropoutAlan J. Flisher, Lorraine Townsend, Perpetual Chikobvu, Carl Lombard, Gary King21. Psychosis and Psychotic disordersA E Gangat 22. Vulnerability of individuals in a family system to develop a psychiatric disorderGerhard Grundling and Eugene Allers23. What does it Uberhaupt mean to "Integrate"?Jürgen Harms24. Research issues in South African child and adolescent psychiatryS M Hawkridge25. New religious movements and psychiatry: The Good NewsV H Hitzeroth26. The pregnant heroin addict: Integrating theory and practice in the development and provision of a service for this client groupV H Hitzeroth, L Kramer27. Autism spectrum disorderErick Hollander28. Recent advances and management in treatment resistanceEric Hollander29. Bipolar mixed statesM. Leigh Janet30. Profile of acute psychiatric inpatients tested for HIV - Helen Jospeh Hospital, JohannesburgA B R Janse van Rensburg31. ADHD - Using the art of film-making as an education mediumShabeer Ahmed Jeeva32. Treatment of adult ADHD co-morbiditiesShabeer Ahmed Jeeva33. Needs and services at ward one, Valkenberg HospitalDr J. A. Joska, Prof. A.J. Flisher34. Unanswered questions in the adequate treatment of depressionModerator: Dr Andre F JoubertExpert: Prof. Tony Hale35. Unanswered questions in treatment resistant depressionModerator: Dr Andre F JoubertExpert: Prof. Sidney Kennedy36. Are mentally ill people dangerous?Sen Z Kaliski37. The child custody circusSean Z. Kaliski38. The appropriatenes of certification of patients to psychiatric hospitalsV. N. Khanyile39. HIV/Aids Psychosocial responses and ethical dilemmasFred Kigozi40. Sex and PsychiatryB Levinson41. Violence and abuse in psychiatric in-patient institutions: A South African perspectiveMarilyn Lucas, John Weinkoove, Dean Stevenson42. Public health sector expenditure for mental health - A baseline study for South AfricaE N Madela-Mntla43. HIV in South Africa: Depression and CD4 countM Y H Moosa, F Y Jeenah44. Clinical strategies in dealing with treatment resistant schizophreniaPiet Oosthuizen, Dana Niehaus, Liezl Koen45. Buprenorphine/Naloxone maintenance in office practice: 18 months and 170 patients after the American releaseTed Parran Jr, Chris Adelman46. Integration of Pharmacotherapy for Opioid dependence into general psychiatric practice: Naltrexone, Methadone and Buprenorphine/ NaloxoneTed Parran47. Our African understanding of individulalism and communitarianismWillie Pienaar48. Healthy ageing and the prevention of DementiaFelix Potocnik, Susan van Rensburg, Christianne Bouwens49. Indigenous plants and methods used by traditional African healers for treatinf psychiatric patients in the Soutpansberg Area (Research was done in 1998)Ramovha Muvhango Rachel50. Symptom pattern & associated psychiatric disorders in subjects with possible & confirmed 22Q11 deletional syndromeJ.L. Roos, H.W. Pretorius, M. Karayiorgou51. Duration of antidepressant treatment: How long is long enough? How long is too longSteven P Roose52. A comparison study of early non-psychotic deviant behaviour in the first ten years of life, in Afrikaner patients with Schizophrenia, Schizo-affective disorder and Bipolar disorderMartin Scholtz, Melissa Janse van Rensburg, J. Louw Roos53. Treatment, treatment issues, and prevention of PTSD in women: An updateSoraya Seedat54. Fron neural networks to clinical practiceM Spitzer55. Opening keynote presentation: The art and science of PsychiatryM Spitzer56. The future of Pharmacotherapy for anxiety disordersDan J. Stein57. Neuropsychological deficits pre and post Electro Convulsive Therapy (ECT) thrice a week: A report of four casesUgash Subramaney, Yusuf Moosa58. Prevalence of and risk factors for Tradive Dyskinesia in a Xhosa population in the Eastern CapeDave Singler, Betty D. Patterson, Sandi Willows59. Eating disorders: Addictive disorders?Christopher Paul Szabo60. Ethical challenges and dilemmas of research in third world countriesGodfrey B. Tangwa61. The interface between Neurology and Psychiatry with specific focus on Somatoform dissociative disordersMichael Trimble62. Prevalence and correlates of depression and anxiety in doctors and teachersH Van der Bijl, P Oosthuizen63. Ingrid Jonker: A psychological analysisL. M. van der Merwe64. The strange world we live in, and the nature of the human subjectVasi van Deventer65. Art in psychiatry: Appendix or brain stem?C W van Staden66. Medical students on what "Soft skills" are about before and after curriculum reformC W van Staden, P M Joubert, A-M Bergh, G E Pickworth, W J Schurink, R R du Preez, J L Roos, C Kruger, S V Grey, B G Lindeque67. Attention deficit hyperactivity disorder (ADHD) - Medical management. Methylphenidate (Ritalin) or Atomoxetine (Strattera)Andre Venter68. A comprehensive guide to the treatment of adults with ADHDW J C Verbeeck69. Treatment of Insomnia: Stasis of the Art?G C Verster70. Are prisoners vulnerable research participants?Merryll Vorster71. Psychiatric disorders in the gymMerryl Vorster72. Ciprales: Effects on anxiety symptoms in Major Depressive DisorderBruce Lydiard
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Goyal, Rakesh, Nicole Nasrah, Dan Johnson, and William Ho. "548 Phase 2 study of FLX475 in combination with ipilimumab in advanced melanoma." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A578. http://dx.doi.org/10.1136/jitc-2021-sitc2021.548.
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BackgroundRegulatory T cells (Treg) can dampen antitumor immune responses in the tumor microenvironment (TME) and have been shown to correlate with poor clinical outcome. Translational studies have demonstrated an accumulation of Treg in tumors after treatment with immunotherapies including CAR-T cells and anti-CTLA-4, which could potentially reflect a mechanism of adaptive immune resistance.1–2 CCR4, the receptor for the chemokines CCL17 and CCL22, is the predominant chemokine receptor on human Treg and is responsible for the migration and accumulation of Treg in the TME. Preclinical studies with orally available CCR4 antagonists have demonstrated potent inhibition of Treg migration into tumors, an increase in the intratumoral Teff/Treg ratio, and antitumor efficacy as a single agent and in combination with checkpoint inhibitors, including anti-CTLA-4.3 In a first-in-human trial conducted in healthy volunteers, the oral CCR4 antagonist FLX475 was demonstrated to be well tolerated with outstanding pharmacokinetic and pharmacodynamic properties.4 An ongoing Phase 1/2 clinical trial of FLX475 is examining the safety and preliminary antitumor activity of FLX475 as monotherapy and in combination with pembrolizumab in subjects with several types of advanced cancer.5 Given the preclinical data demonstrating a significant enhancement of the antitumor activity of anti-CTLA-4 when combined with FLX475, a Phase 2 study investigating the combination of FLX475 and ipilimumab is now being conducted in subjects with advanced melanoma.MethodsThis clinical trial is a Phase 2, multicenter, open-label, single-arm study to determine the antitumor activity of FLX475 in combination with ipilimumab in subjects with advanced melanoma previously treated with an anti-PD-1 or anti-PD-L1 agent. The primary objectives of the study are to evaluate objective response rate, and the safety and tolerability of this combination. The study will first examine the safety of the combination of the 100 mg PO QD recommended Phase 2 dose of FLX475 and the approved 3 mg/kg IV Q3W dose of ipilimumab as part of a safety run-in phase, prior to examining the degree of antitumor activity in approximately 20 subjects. Evidence of an overall response rate (ORR) notably greater than the expected ORR of ipilimumab monotherapy alone in such subjects, which has been shown to be approximately 14%,6 would provide preliminary clinical evidence in support of the clinical hypothesis that CCR4 blockade by FLX475 can significantly enhance the antitumor activity of an anti-CTLA-4 checkpoint inhibitor.Trial RegistrationClinicalTrials.gov Identifier: NCT04894994ReferencesO’Rourke D, Nasrallah M, Desai A, Melenhorst J, Mansfield K, Morrissette J, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey S, Navenot J, Zheng Z, Levine B, Okada H, June C, Brogdon J, Maus M. A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma. Sci Transl Med 2017;9:eaaa0984. doi: 10.1126/scitranslmed.aaa0984.Sharma A, Subudhi S, Blando J, Vence L, Wargo J, Allison JP, Ribas A, Sharma P. Anti-CTLA-4 immunotherapy does not deplete FOXP3+ regulatory T cells (Tregs) in human cancers-Response. Clin Cancer Res 2019;25:1233–1238.Marshall L, Marubayashi S, Jorapur A, Jacobson S, Zibinsky M, Robles O, Hu D, Jackson J, Pookot D, Sanchez J, Brovarney M, Wadsworth A, Chian D, Wustrow D, Kassner P, Cutler G, Wong B, Brockstedt D, Talay O. Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4. J Immunother Cancer 2020;8:e000764.van Marle S, van Hoogdalem E, Johnson D, Okal A, Kassner P, Wustrow D, Ho W, Smith S. Pharmacokinetics, pharmacodynamics, and safety of FLX475, an orally-available, potent, and selective small-molecule antagonist of CCR4, in healthy volunteers. J Immunother Cancer 2018; 6(Suppl 1):P484(SITC 2018).Powderly J, Chmielowski B, Brahmer J, Piha-Paul S, Bowyer S, LoRusso P, Catenacci D, Wu C, Barve M, Chisamore M, Nasrah N, Johnson D, Ho W. Phase I/II dose-escalation and expansion study of FLX475 alone and in combination with pembrolizumab in advanced cancer. Journal of Clinical Oncology 2020;38(15_suppl): TPS3163 (ASCO 2020).Long G, Mortier L, Schachter J, Middleton M, Neyns B, Sznol M, Zhou H, Ebbinghaus S, Ibrahim N, Arance A, Ribas A, Blank C and Robert C. Society for Melanoma Research 2016 Congress. Pigment Cell & Melanoma Research 2017;30:76–156.Ethics ApprovalThis study has been approved by the Institutional Review Board at each investigational site.
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Hill, J. H., R. Alleman, D. B. Hogg, and C. R. Grau. "First Report of Transmission of Soybean mosaic virus and Alfalfa mosaic virus by Aphis glycines in the New World." Plant Disease 85, no. 5 (May 2001): 561. http://dx.doi.org/10.1094/pdis.2001.85.5.561c.
Full textAbstract:
The recent discovery of the soybean aphid, Aphis glycines Matsamura, in the North Central region of the United States is significant because it is the first time that a soybean-colonizing aphid has been detected in the New World. Although the aphid has the potential to cause physiological loss of up to 52% on soybeans (4), it can also transmit Soybean mosaic virus (SMV). Transmission of Alfalfa mosaic virus (AMV) has not been reported. SMV, and less commonly AMV, are found in soybeans in the North Central states and are transmitted by numerous aphids in a nonpersistent manner (2; Grau, unpublished). For SMV, potential exists for specificity of transmission between virus strain and aphid species (3). For these reasons, it was important to determine if an endemic isolate of these viruses could be transmitted by this introduced species of aphid in the North Central region. Transmission experiments were conducted as described (3), using 3, 5, and 10 aphids per plant. Ten plants of the soybean cultivar Williams 82 were used for each treatment. To preclude confounding results by possible seed transmission, plants used in all tests were grown from seeds harvested from virus-indexed plants grown in the greenhouse. For experiments involving SMV, the aphid-transmissible field isolate Al5 (GeneBank Accession no. AF242844) and, as a negative control, the non-aphid transmissible isolate N (GeneBank Accession no. D500507) were used. For experiments involving AMV, a field isolate of AMV, confirmed by ELISA and host range, was used. The aphid species Myzus persicae was maintained on broad bean and A. glycines was maintained on virus-free soybean. The protocol for transmission studies of AMV was identical to that used in the SMV study, except only A. glycines was tested. For experiments, plants were periodically observed for symptom development and tested by ELISA 4 to 5 weeks after inoculation access. No transmission of SMV-N occurred in any tests, which together involved 180 aphids each of M. persicae or A. glycines. For the Al5 isolate, transmission efficiencies of 30, 50, and 50% were obtained with 3, 5, and 10 individuals, respectively, of M. persicae per plant. Efficiencies for A. glycines were 30, 40, and 40%. Transmission levels by the two aphid species did not differ significantly (t-test, P = 0.01). For AMV, corresponding transmission efficiencies were 0, 0, and 20%. The data suggest that the introduced A. glycines can be an efficient vector of SMV, but a less efficient vector of AMV, in the North Central region. Transmission of AMV by M. persicae has been documented (1) but was not examined in this study. Transmission of SMV and AMV by A. glycines is of concern because it may increase SMV and AMV incidence. With the recent outbreak of Bean pod mottle virus (BPMV) in the region, the potential for synergism of SMV and BPMV is increased (2). References: (1) M. B. Castillo and G. G. Orlob. Phytopathology 56:1028, 1966. (2) G. L. Hartman et al., eds. 1999. Compendium of Soybean Diseases, 4th Ed. American Phytopathological Society, St. Paul, MN. (3) B. S. Lucas and J. H. Hill. Phytopathol. Z. 99:47, 1980. (4) C. L. Wang et al. Plant Prot. 20:12, 1994.
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Triani, Lili, Sofia Hartati, and R. Sri Martini Meilani. "Tueak Serembeak: The Role of Parenting in Early Character Development and Education." JPUD - Jurnal Pendidikan Usia Dini 15, no. 2 (November 30, 2021): 281–99. http://dx.doi.org/10.21009/jpud.152.05.
Full textAbstract:
The challenge of implementing character education has an impact on the development of children's character. This study aims to describe the form of parenting using tueak serembeak in early character development and education in the Rejang tribe. This qualitative research uses a case study method with two male respondents. Data was collected by documentation, interviews, observations, and field notes and analysed using the Miles and Huberman stages. The theoretical study as the basis of research shows that tueak serembeak can form twelve characters in early childhood, responsibility, courage to take decisions, sharing, caring, survival, tenacity, cooperation, hard work, never give up, keep the spirit, dare to accept challenges, and be patient in dealing with problems. However, the findings in the field show that there are only four characters that appear, being responsible, sharing, caring and patient in dealing with problems. Other characters that appear not based on the teachings of tueak serembeakare independent, creative, and friendly characters. This happens because of the influence of external intervention, education in Air Raman Village, which has developed, advanced technology and open community life. A suggestion for further research, is experimental research based on tueak serembeak teachings that can explain more clearly the influence of this teaching on other aspects of child development.
Keywords: Early Character Development, Parenting, Tueak Serembeak
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Azevedo, Mário Luiz Neves de. "Bem público, teoria do capital humano e mercadorização da educação: aproximações conceituais e uma apresentação introdutória sobre "público" nas Declarações da CRES-2008 e CRES-2018 (Public good, human capital theory and commodification of education)." Revista Eletrônica de Educação 13, no. 3 (September 2, 2019): 873. http://dx.doi.org/10.14244/198271993591.
Full textAbstract:
The purpose of this article is to analyze the so-called human capital theory and to clarify the concept of public good, as well as the frequency of the expression "public" in the Declarations adopted at the Regional Conferences of Higher Education in Latin America and the Caribbean in 2008 and 2018. For this, in methodological terms, this article analyzes documents from certain International Organizations (UNESCO, World Bank and OECD) and seeks theoretical support in Reinhart Koselleck's History of Concepts and other authors such as Roger Dale, Susan Robertson, Bob Jessop, Stephen Gill, Paul Samuelson , Karl Polanyi and Pierre Bourdieu.ResumoO presente artigo tem o objetivo de analisar a chamada teoria do capital humano e precisar o conceito de bem público, bem como a frequência da expressão “público” nas Declarações aprovadas nas Conferências Regionais de Educação Superior na América Latina e Caribe, em 2008 e 2018. Para isto, em termos metodológicos, o presente artigo analisa documentos de determinadas Organizações Internacionais (UNESCO, Banco Mundial e OCDE) e busca apoio na História dos Conceitos de Reinhart Koselleck e em autores como Roger Dale, Bob Jessop, Stephen Gill, Paul Samuelson, Karl Polanyi, Pierre Bourdieu.Keywords: Public good, Human capital theory, Commodification, Education, CRES 2008 and CRES 2018.Palavras-chave: Bem público, Teoria do capital humano, Mercadorização, Educação, CRES 2008 e CRES 2018.ReferencesALVES, Giovanni. O que é o precariado? Blog da Boitempo. Extraído de <https://blogdaboitempo.com.br/2013/07/22/o-que-e-o-precariado/>, 22 Jul 2013, acesso em 28 fev 2019.ARENDT, Hannah. A crise na educação. In: Entre o passado e o futuro. Tradução: Mauro W. Barbosa de Almeida. 3ª reimpressão da 5ª ed. de 2000. São Paulo: Perspectiva, 2005.AUDITORIA CIDADÃ DA DÍVIDA. Dividômetro: quanto pagamos (juros e amortizações) – dívida pública federal. Auditoria Cidadã da Dívída. 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Кючуков, Хрісто. "“Parno Sar Papin – White as a Swan”, Or How Metaphors Help Roma Children to Acquire Grammatical Categories in Romani." East European Journal of Psycholinguistics 4, no. 1 (June 27, 2017): 100–113. http://dx.doi.org/10.29038/eejpl.2017.4.1.kyu.
Full textAbstract:
The paper presents the process of language socialization and acquisition of grammatical categories through the Roma oral culture in which metaphors are extensively used. Roma children who grow up in extended Roma families and community learn the language through communication with speakers of different registers. Research with 22 Roma children between three and six years of age from Croatia was carried in order to find out what grammatical categories are learned in this period of the life of children. The children were tested with a specially designed language assessment test in Romani (Kyuchukov & de Villiers, 2014b). The results show that Roma boys perform the test much better than Roma girls. Boys learn Romani from folkloristic genres which are rich in metaphors and this helps them to acquire complex grammatical categories.
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Akmal, Yenina, Hikmah, Astari, and Ichtineza Halida Hardono. "Preparing for Parenthood; Parenting Training Module on six Child Development Aspect in East Jakarta." JPUD - Jurnal Pendidikan Usia Dini 13, no. 2 (December 12, 2019): 371–85. http://dx.doi.org/10.21009/jpud.132.12.
Full textAbstract:
The age period of 0-8 years is the most important moment for every human being to develop all the developmental features supported by parents at home and teachers / tutors at the Early Childhood Education Institute (ECE). In parenting, six main aspects must be known and applied by each parent. Lack of education, nutritional knowledge, care and care, and aspects of clean-living habits in the family can have an impact on children's growth and development processes. This study aims to develop a module 6 aspects of child development for parental guidance. This study uses a research and development approach to test the effectiveness of the posttest design. Respondents in this study are parents who have children up to 5 years and early childhood educators. The findings show that from these six main aspects, it seems that parents and ECE tutors do not yet understand the ECE concept. In another perspective, there is still a lack of knowledge about these 6 main aspects which require training and parenting modules to develop the 6 aspects of child development.
Keywords: Early Childhood Education, Child Development Aspect, Parenting Training Module
References:
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Rahman, Md Naimur. "Urban Expansion Analysis and Land Use Changes in Rangpur City Corporation Area, Bangladesh, using Remote Sensing (RS) and Geographic Information System (GIS) Techniques." Geosfera Indonesia 4, no. 3 (November 25, 2019): 217. http://dx.doi.org/10.19184/geosi.v4i3.13921.
Full textAbstract:
This study aim to attempt mapping out the Land Use or Land Cover (LULC) status of Regional Project Coordination Committee (RPCC) between 2009-2019 with a view of detecting the land consumption rate and the changes that has taken place using RS and GIS techniques; serving as a precursor to the further study on urban induced variations or change in weather pattern of the cityn Rangpur City Corporation(RCC) is the main administrative functional area for both of Rangpur City and Rangpur division and experiencing a rapid changes in the field of urban sprawl, cultural and physical landscape,city growth. These agents of Land use or Land cover (LULC) varieties are responsible for multi-dimensional problems such as traffic congestion, waterlogging, and solid waste disposal, loss of agricultural land. In this regard, this study fulfills LULC changes by using Geographical Information Systems (GIS) and Remote Sensing (RS) as well as field survey was conducted for the measurement of change detection. The sources of data were Landsat 7 ETM and landsat 8 OLI/TIRS of both C1 level 1. Then after correcting the data, geometrically and radiometrically change detection and combined classification (supervised & unsupervised) were used. The study finds LULC changes built-up area, water source, agricultural land, bare soil in a change of percentage is 17.23, 2.58, -9.94, -10.19 respectively between 2009 and 2019. Among these changes, bare soil is changed to a great extent, which indicates the expansion of urban areas is utilizing the land to a proper extent.
Keywords: Urban expansion; land use; land cover; remote sensing; geographic information system (GIS); Rangpur City Corporation(RCC).
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Grignani, Giovanni, Piotr Rutkowski, Celeste Lebbe, Natalie Prinzi, Jean-jaques Grob, Enrica Teresa Tanda, Michele Guida, et al. "545 A phase 2 study of retifanlimab in patients with advanced or metastatic merkel cell carcinoma (MCC) (POD1UM-201)." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A574—A575. http://dx.doi.org/10.1136/jitc-2021-sitc2021.545.
Full textAbstract:
BackgroundRetifanlimab (INCMGA00012) is a humanized, hinge-stabilized immunoglobulin G4 kappa (IgG4κ), anti-programmed cell death protein (PD)-1 monoclonal antibody with safety and clinical pharmacology that are characteristic for the class. Evaluation of retifanlimab in solid tumors is under investigation in phase 2 and 3 studies. POD1UM-201 is an open-label, single-arm, multicenter, phase 2 study evaluating the efficacy and safety of retifanlimab in patients with chemotherapy-naïve or chemotherapy-refractory advanced/metastatic Merkel cell carcinoma (MCC). Updated results from the chemotherapy-naïve cohort are reported here.MethodsEligible patients were ≥18 years of age, had metastatic or recurrent unresectable loco-regional MCC, Eastern Cooperative Oncology Group performance status ≤1, measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, and had not received prior systemic treatment for MCC. Retifanlimab 500 mg IV every 4 weeks (Q4W) was administered for up to 2 years. The primary endpoint was overall response rate (ORR) assessed by independent central review per RECIST v1.1. Secondary endpoints included duration of response, disease control rate (DCR; defined as proportion of patients with either an objective response or stable disease lasting at least 6 months), progression-free survival, overall survival, safety, and pharmacokinetics.ResultsAs of April 16, 2021, 87 patients with chemotherapy-naïve advanced/metastatic MCC had received retifanlimab. Per protocol, the primary efficacy analyses are based on the first 65 patients assessed. At the data cutoff, 34 of these 65 patients (52.3%) were on treatment; 4 (6.2%) had completed treatment; and 27 (41.5%) had discontinued treatment for reasons including disease progression (18 [27.7%]), adverse event (AE; 7 [10.8%]), death (1 [1.5%]), and physician decision (1 [1.5%]). The ORR in these patients was 46.2% (n=30: complete response, 8 [12.3%]; partial response, 22 [33.8%]). The DCR was 53.8% (n=35). Other secondary efficacy results are not yet mature. Among all treated patients (n=87), 66 (75.9%) had a treatment-emergent AE (TEAE), 25 (28.7%) had a grade ≥3 TEAE, and 12 (13.8%) had a grade ≥3 treatment-related AE. Twenty-three patients (26.4%) had an immune-related AE (irAE), and 8 (9.2%) had a grade ≥3 irAE. Four patients (4.6%) discontinued treatment due to irAEs (peripheral sensorimotor neuropathy, pancreatitis, eosinophilic fasciitis, and polyarthritis [each n=1]). One patient (1.1%) had a grade 3 infusion reaction.ConclusionsThese data from the POD1UM-201 trial show that retifanlimab monotherapy at 500 mg Q4W continues to demonstrate promising clinical activity and safety in patients with advanced/metastatic chemotherapy-naïve MCC. Updated results will be presented at the meeting.AcknowledgementsThe study is sponsored by Incyte Corporation (Wilmington, DE). Statistical support was provided by Xiaohan Xu of Incyte Corporation. Editorial assistance was provided by Matthew Bidgood of Envision Pharma Group (Philadelphia, PA, USA).Trial RegistrationClinicaltrials.gov NCT03599713; EudraCT 2018-001627-39Ethics ApprovalThe study was approved by institutional review boards or independent ethics committees in Canada (McGill University Health Center-Research Ethics Board [MP-37-2019-5103, MEO-37-2019-1616]; Ontario Cancer Research Ethics Board [1728]; Health Research Ethics Board of Alberta – Cancer Committee [HREBA.CC-19-0004, HREBA.CC-19-0020]); Czech Republic (Eticka komise Fakultni nemocnice Kralovske Vinohrady, Eticka komise IKEM a FTNsP, Eticka komise Nemocnice Na Bulovce, Statni ustav pro kontrolu leciv, Eticka komise FN a LF UP Olomouc [169/18MEK24, LEK/04/07/2018, (L-18-85) 8522/23.3.2021, 22.3.2021/9965/EK-Z]); France (Comité de Protection des Personnes Ile de France X [CNRIPH : 18.11.19.49212/Id. 2043]; Agence Nationale de Sécurité du Médicament et des Produits de Santé); Germany (Ethik-Kommission der Medizinischen Fakultaet der Universitaet Duisburg-Essen [18-8371-AF]; Bundesamt fuer Strahlenschutz; Paul-Ehrlich Institute); Hungary (Egeszsegugyi Tudomanyos Tanacs Klinikai Farmakologiai Etikai Bizottsaga [IV/2407-0/2021-EKL, OGYÉI/11697-2/2021]; Orszagos Gyogyszereszeti es Elelmezes-egeszsegugyi Intezet); Italy (Comitato Etico IRCCS Pascale Napoli [116/21 E - 87/18]; Comitato Etico IRCCS di Candiolo [232/2021]; Istituto Tumori Giovanni Paolo II IRCCS Ospedale Oncologico Bari [736/CE]; Comitato Etico Locale per la Sperim. Clin. dei Medicinali dell’Az. Osp.ra Univ.ria Senese di Siena [14107]; Comitato Etico dell’IRCCS Istituto Nazionale per la Ricerca sul Cancro di Genova [389/2018 - 24/05/2021]; Comitato etico degli IRCCS Istituto Europeo di Oncologia e Centro Cardiologico Monzino [IEO 948 - RE3065/IB Edition 7 dated 10Nov2020 (SA7)]; Comitato Etico, Fondazione IRCCS Istituto Nazionale dei Tumori, .c. Medicina Oncologica 1 – Fondazio [INT 01/19]; Comitato Etico IRCCS Istituto Oncologico Veneto di Padova [EM 109/2021]; Comitato Etico dell’IRCCS Istituto Dermopatico dell’Immacolata Ospedale Generale S. Carlo di Roma [550/7]; AIFA – Agenzia Italiana del Farmaco [0040152-01/04/2021-AIFA-AIFA_USC-P]; Comitatao Etico Policlinico di Modena [1017/2018/FARM/AOUMO - EMENDAMENTO SOSTANZIALE IB EDIZIONE 7 DEL 10/11/20 (201800162739-010) (p. 9869/21)]); Poland (Komisja Bioetyczna przy Centrum Onkologii [no. 55/2019]; Office for Registration of Medicinal Products, Medical Devices and Biocidal Products [UR/DBL/D/328/2019]); Spain (CEIC Hospital General Universitario Gregorio Marañon [280/18]; Agencia Española del Medicamento y Productos Sanitarios); Switzerland (Kantonale Ethikkommission Zürich (KEK-Zürich) [2019-00200]; Swissmedic [2019DR2035]); United Kingdom (North East – York Research Ethics Committee [248465]; Medicines and Healthcare products Regulatory Agency; Health Research Authority); United States (Copernicus Group IRB; Western Institutional Review Board [20181738, Work order number -– IQV1-18-309]; Roswell Park Cancer Institute IRB [STUDY00000802/P 75918]; Inova Institutional Review Board, Human Research Protection Program; Stanford IRB Research Compliance Office [48198]; Rush University Medical Center [18072304-IRB01]; University of Miami IRB; Mayo Clinic IRB – Rochester).
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Ahmad Sabri. "Trends of “Tahfidz House” Program in Early Childhood Education." JPUD - Jurnal Pendidikan Usia Dini 14, no. 1 (April 30, 2020): 71–86. http://dx.doi.org/10.21009/jpud.141.06.
Full textAbstract:
The enthusiasm in the Tahfidz House (TH) education program especially for children shows an increasing trend in Padang, a modeling city in developing Islāmic character for children. The purpose of this study was to investigate the Tahfidz House program trends development in early childhood in Padang. This study uses qualitative methods with data collection tools, namely inter- views, direct observation, and document analysis. The results showed that: First, the Tahfidz House program attracted public interest because it offered dimensions of character formation such as in- creasing Intelligence Quotient, Emotional Quotient, and Spiritual Quotient. Second, there is a theo- logical reason in the landscape of local people to think that the Qur'an offers a blessing concept in our lives. Third, Tahfidz House existences as non-formal education has two dominant affiliations, namely pure education and based on market interests or capitalization.
Keywords: Early Childhood Education, Tahfidz House Program, Market Interest
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Марченко, Олег. "РИСИ СУСПІЛЬНО-ПОЛІТИЧНИХ ТРАНСФОРМАЦІЙ В РОСІЙСЬКІЙ ІМПЕРІЇ ПОЧАТКУ XVIIІ СТ." Уманська старовина, no. 9 (December 23, 2022): 27–39. http://dx.doi.org/10.31499/2519-2035.9.2022.269855.
Full textAbstract:
Ключові слова: Російська імперія першої половини XVIIІ ст., реформи Петра І, самодержавство,абсолютна монархія, мілітаризм.
На основі аналізу історичних досліджень поданий неупереджений погляд на передумови, хід, наслідкиспроб Петра І модернізувати Російську державу й суспільство на початку XVIIІ ст. Аналізується еволюціяпоглядів істориків різних епох щодо особистості Петра, причин, умов, характеру, мотиваційних чинників, щовпливали на прийняття ним тих чи інших рішень щодо проведення реформ.У результаті проведеного дослідження визначені основні риси суспільно-політичних трансформацій вРосійській імперії першої половини XVIIІ ст., акцентовано увагу на спростування радянських та сучаснихросійських міфів щодо розвитку імперської, самодержавної моделі Росії, показані тенденції в економіці,державному управлінні, характері влади, взаєминах між владою та її підданими, у культурі, ментальності, яківизначали поведінку тодішньої «еліти» та населення країни, і надалі є характерними для сучасної Росії(імперське мислення, неповага до закону, обмеження прав і свобод громадян, панування в суспільстві страху,насилля, віри в непогрішність влади, культурне невігластво тощо).
Посилання
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Adas Saliba, Tania, Lia Borges de Mattos Custodio, Lourenço Vieira Tereza Canevari, Nemre Adas Saliba, and Suzely Adas Saliba Moimaz. "Escova dentária: a escolha do consumidor." ARCHIVES OF HEALTH INVESTIGATION 9, no. 6 (December 16, 2020): 609–13. http://dx.doi.org/10.21270/archi.v9i6.4743.
Full textAbstract:
A higiene bucal, parte integrante dos cuidados corporais, é realizada com o auxílio de dispositivos, em especial, a escova dental. Com a evolução tecnológica, as escovas dentais passaram a ser fabricadas com diferentes materiais. Objetivou-se investigar as marcas e modelos de escovas dentárias disponíveis no mercado brasileiro; analisar a legislação vigente sobre a produção e verificar as informações fornecidas pelo fabricante ao consumidor final. Trata-se de um estudo transversal, descritivo, qualitativo, de análise documental. Foi realizado levantamento nas páginas eletrônicas da Agencia Nacional de Vigilância Sanitária e do Instituto Nacional de Metrologia, Qualidade e Tecnologia sobre a legislação vigente, que estabelece as características exigidas para produção e comercialização de escovas dentárias. Foram pesquisadas marcas e modelos disponíveis no mercado brasileiro, nas páginas eletrônicas das empresas, fabricantes ou importadoras e em pontos de vendas para o consumidor final para verificar as informações disponíveis nas embalagens. A Resolução N° 54/17 da Diretoria Colegiada da ANVISA, estabelece algumas características físicas, tais como: largura máxima da cabeça e comprimento mínimo da escova dentária. Foram incluídos nesta pesquisa 20 marcas comerciais, as quais distribuem 108 modelos no mercado brasileiro. Apenas 2 modelos (1,85%) apresentaram todas as informações exigidas pela resolução da ANVISA, sendo a “supervisão do adulto” e “orientação do dentista” os itens menos contemplados. Não apresentaram indicação para uso adulto ou infantil 44,4% do total. Conclui-se, que existem muitas marcas e modelos no mercado brasileiro, porém faltam informações importantes para o profissional realizar a indicação apropriada e o paciente, a aquisição consciente.
Descritores: Escovação Dentária; Higiene Bucal; Saúde Bucal.
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Rezaeipour, Mohammadreza. "Rejection of vaccination against the COVID-19 virus will increase morbidity and mortality." International Journal of Endocrinology: Diabetes and Metabolism 1, no. 1 (November 10, 2021): 1–2. http://dx.doi.org/10.55124/ijde.v1i1.134.
Full textAbstract:
It has been about two years since the first COVID-19 epidemic began,now it coincides with the fifth peak of epidemic infection in some countries. Over the years we have experienced many ups and downs of this virus(1, 2). It has been about two years since the first COVID-19 epidemic began,now it coincides with the fifth peak of epidemic infection in some countries. Over the years we have experienced many ups and downs of this virus(1, 2). Some people are still with us, but unfortunately, some have left us in the middle of their lives, and they have become victims of the COVID-19 pandemic(3). A virus that when it got into the world of people, many said: "It does not last long and when it reaching warm seasons of the year, it will die prematurely and does not survive." However, the virus has survived to this today. Efforts have been made around the world to shine the bright rays of hope and life in the shady cornerscreated by it(4, 5). One of these constructive efforts is to obtain a vaccine against COVID-19. COVID-19 vaccination rates have still not been optimal in some countries(6, 7). While China, India, and the United States have had the highest vaccination rates (over 100%) since August 4, 2021, the statistics are disappointing in some other countries(8). For example, approximately 1.16% of Iranians received vaccinations at the same time(6-8). This is not sufficient to achieve so-called herd immunity, and hospitals have become more crowded due to the serious spread of the more contagious type of delta. In addition to the lack of appropriate vaccines due to economic sanctions following the political tensions in some countries,such as Iran(9, 10), the reasons for refusing free injections and neglecting preventive measures are also different(5). The covid-19 virus survived and mutant and increased mortality. However, still, some people don't hear and look at these facts. The efforts of medical staff across the globe have not yet been properly heard(5). What remains are the challenges that have endangered human life on earth, and we seem to be counting it down. These barriers must be identified in a short time. The workload of medical staff has grown significantly. In addition, journalists and the press have come to their aid, reporting and promoting the views of professors, experts, and heads of the health care system in the press, and enlightenment efforts have reached the point where politicians are talking about COVID-19 in election campaigns(11). Although an unknown and difficult path has been taken so far, it seems that this path is still ahead(7). In addition to government agencies, removing these barriers requires residents' campaigns to get vaccinated for their health, for their grandparents, for their neighbors, or to use free incentives(5, 12). Failure to do so will result in significant health costs for governments and economies.Failure to get COVID-19 vaccination in most cases leads to hospitalization and usually leads to large bills. These expenses will be higher for the uninsured person. It also enhances the likelihood of re-globalization pandemic with its mutant strains(13). References: Ferrer, R COVID-19 Pandemic: the greatest challenge in the history of critical care. Medicina intensiva. 2020;44(6):323. He, J.; Chen, G.; Jiang, Y.; Jin, R.; Shortridge, A.; Agusti, S et al. Comparative infection modeling and control of COVID-19 transmission patterns in China, South Korea, Italy and Iran. Science of the Total Environment. 2020;747:141447. Stock, AD.; Bader, ER.; Cezayirli, P.; Inocencio, J.; Chalmers SA, Yassari R, et al. COVID-19 infection among healthcare workers: serological findings supporting routine testing. Frontiers in medicine. 2020;7:471. Rezaeipour, M COVID-19-Related Weight Gain in School-Aged Children. International Journal of Endocrinology and Metabolism. 2021;19(1). Lazarus, JV.; Ratzan, SC.; Palayew, A.; Gostin, LO.; Larson, HJ.; Rabin, K et al. A global survey of potential acceptance of a COVID-19 vaccine. Nature medicine. 2021;27(2):225-8. Basiri N, Koushki M. Study of Vaccine Production Abroad and Scientific and Research Challenges of COVID-19 Vaccine Production in Iran. Annals of the Romanian Society for Cell Biology. 2021:17249-56. 7.Maserat, E.; Keikha, L.; Davoodi, S.; Mohammadzadeh, Z. E-health roadmap for COVID- 19 vaccine coverage in Iran. BMC Public Health. 2021;21(1):1-11. Mathieu, E.; Ritchie, H.; Ortiz-Ospina, E.; Roser, M.; Hasell, J.; Appel, C et al. A global database of COVID-19 vaccinations. Nature human behaviour. 2021:1-7. Rustamovich, KM The Impact of Economic Sanctions on Well-being of Vulnerable Populations of Target Countries. International Journal on Economics, Finance and Sustainable Development. 2019;1(1):17-20. Setayesh, S.; Mackey, TK.; Addressing the impact of economic sanctions on Iranian drug shortages in the joint comprehensive plan of action: promoting access to medicines and health diplomacy. Globalization and health. 2016;12(1):1-14. Aten, M.; Transnational Kleptocracy and the COVID-19 Pandemic How to Contain the Spread? Transnational Kleptocracy and the COVID-19 Pandemic Containing the Spread. 2021:4. Paul, E.; Steptoe, A.; Fancourt, D.; Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications. The Lancet Regional Health-Europe. 2021;1:100012. Desapriya, E.; Parisa, K.; Gunatunge, K. RE: Global deaths from COVID-19 have surpassed 3 million in mid of April, 2021. 2021.
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Montero Fenollós, Juan-Luis. "De Mari a Babilonia: ciudades fortificadas en la antigua Mesopotamia." Vínculos de Historia Revista del Departamento de Historia de la Universidad de Castilla-La Mancha, no. 11 (June 22, 2022): 15–32. http://dx.doi.org/10.18239/vdh_2022.11.01.
Full textAbstract:
Las ciudades mesopotámicas estaban amuralladas desde sus orígenes. Muralla y ciudad, símbolo de civilización, eran dos conceptos inseparables. Por mandato de los dioses, el rey era el responsable de la fundación de las ciudades y de la construcción de sus sistemas de defensa, que fueron evolucionando como respuesta a los cambios producidos en el arte de la guerra en el Próximo Oriente antiguo. En este artículo se analiza, en particular, la documentación arqueológica y textual de dos modelos de ciudad fortificada: Mari (III-II milenio a. C.), en el norte, y Babilonia (II-I milenio a. C.), en el sur. Se realiza una nueva propuesta de interpretación del recinto defensivo interior de Babilonia. Palabras clave: Ciudades mesopotámicas, fortificacionesTopónimos: Habuba Kabira, Mari, BabiloniaPeríodo: IV-I milenio a. C. ABSTRACTMesopotamian cities were walled from their origins. Wall and city, a symbol of civilisation, were two inseparable concepts. By mandate of the gods, the king was responsible for the foundation of the cities and the construction of their defence systems, which evolved in response to changes in the art of warfare in the ancient Near East. This article analyses, in particular, the archaeological and textual documentation of two models of fortified cities: Mari (3rd-2nd millennium B.C.), in the north, and Babylon (2nd-1st millennium B.C.), in the south. A new approach to the interpretation of the inner wall of Babylon is proposed. Keywords: Mesopotamian cities, fortificationsPlace names: Habuba Kabira, Mari, BabylonPeriod: IVth-Ist millennium B. C. REFERENCIASAbrahami, Ph. (1997), L’armée à Mari, tesis doctoral, Université de Paris I (inédita).al-Rawi, F.N.H. (1985), “Nabopolassar’s Restoration Work on the Wall Imgur-Enlil at Babylon”, Iraq, 47, pp. 1-9.Aurenche, O. (dir.) (1977), Dictionnaire illustré multilingue de l’architecture du Proche Orient Ancien, Lyon, MOM.Azara, P. (dir.) 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Ungureanu, James C. "Science, Religion, and the Protestant Tradition: Retracing the Origins of Conflict." Perspectives on Science and Christian Faith 73, no. 3 (September 2021): 173–75. http://dx.doi.org/10.56315/pscf9-21ungureanu.
Full textAbstract:
SCIENCE, RELIGION, AND THE PROTESTANT TRADITION: Retracing the Origins of Conflict by James C. Ungureanu. Pittsburgh, PA: University of Pittsburgh Press, 2019. x + 358 pages. Hardcover; $50.00. ISBN: 9780822945819. *Mythical understandings about historical intersections of Christianity and science have a long history, and persist in our own day. Two American writers are usually cited as the architects of the mythology of inevitable warfare between science and religion: John William Draper (1811-1882) and Andrew Dickson White (1832-1919). Draper was a medical doctor, chemist, and historian. White was an academic (like Draper), a professional historian, and first president of the nonsectarian Cornell University. Ungureanu's objective is to show how Draper and White have been (mis)interpreted and (mis)used by secular critics of Christianity, liberal theists, and historians alike. *Ungureanu opens by critiquing conflict historians as misreading White and Draper. The conflict narrative emerged from arguments within Protestantism from the sixteenth through nineteenth centuries, and, as taken up by Draper and White, was intended not to annihilate religion but to reconcile religion with science. Consequently, the two were not the anti-religious originators of science-versus-religion historiography. Rather, the "warfare thesis" began among sixteenth- and seventeenth-century Protestant historians and theologians attacking both Roman Catholics and each other. By the early nineteenth century, the purpose of conflict polemics was not to crush religion in the name of science but to clear intellectual space for preserving a "purified" and "rational" religion reconciled to science. Widespread beliefs held by liberal Protestant men of science included "progressive" development or evolution in history and nature as found, for example, in books by Lamarck in France and Robert Chambers in Britain. For Draper, English chemist and Unitarian minister Joseph Priestley (1733-1804) was a model of faith without the burden of orthodoxy. *So conflict rhetoric arose not, as we've been taught before, in post-Darwinian controversies, but in contending narratives within generations of earlier Protestant reformers who substituted personal judgment for ecclesial authority. Victorian scientific naturalists and popularizers often rejected Christian theological beliefs in the name of a "natural" undogmatic "religion" (which could slip into varieties of Unitarianism, deism, agnosticism, or pantheism). In effect, the conflict was not between science and religion, but between orthodox Christian faith and progressive or heterodox Christian faith--a conflict between how each saw the relationship between Christian faith and science. Draper, White, and their allies still saw themselves as theists, even Protestant Christians, though as liberal theists calling for a "New Reformation." Given past and present anti-Christian interpretations of these conflict historians with actual religious aims, this is ironic to say the least. *Ungureanu's thesis shouldn't be surprising. In the Introduction to his History of the Warfare, White had written: "My conviction is that Science, though it has evidently conquered Dogmatic Theology based on biblical texts and ancient modes of thought, will go hand in hand with Religion … [i.e.] 'a Power in the universe, not ourselves, which makes for righteousness' [quoting without attribution Matthew Arnold, who had actually written of an 'eternal power']." *As science advanced, so would religion: "the love of God and of our neighbor will steadily grow stronger and stronger" throughout the world. After praising Micah and the Epistle of James, White looked forward "above all" to the growing practice of "the precepts and ideals of the blessed Founder of Christianity himself" (vol. 1, p. xii). Ungureanu quotes White that the "most mistaken of all mistaken ideas" is the "conviction that religion and science are enemies" (p. 71). *This echoed both Draper's belief that "true" religion was consistent with science, and T. H. Huxley's 1859 lecture in which he affirmed that the so-called "antagonism of science and religion" was the "most mischievous" of "miserable superstitions." Indeed, Huxley affirmed that, "true science and true religion are twin-sisters" (p. 191). *Chapter 1 locates Draper in his biographical, religious, and intellectual contexts: for example, the common belief in immutable natural laws; the "new" Protestant historiography expressed in the work of such scientists as Charles Lyell and William Whewell; and various species of evolutionism. Comte de Buffon, Jean Baptiste Lamarck, John Herschel, Thomas Dick, Robert Chambers, and Darwin are some of the many writers whose work Draper used. *Chapter 2 examines White's intellectual development including his quest for "pure and undefiled" religion. He studied Merle d'Aubigné's history of the Reformation (White's personal library on the subject ran to thirty thousand items) and German scholars such as Lessing and Schleiermacher who cast doubt on biblical revelation and theological doctrines, in favor of a "true religion" based on "feeling" and an only-human Jesus. As he worked out his history of religion and science, White also absorbed the liberal theologies of William Ellery Channing, Horace Bushnell, Henry Ward Beecher, and Lyman Abbott, among others. *The resulting histories by Draper and White were providential, progressive, and presentist: providential in that God still "governed" (without interfering in) nature and human history; progressive, even teleological, in that faith was being purified while science grew ever closer to Truth; and presentist in that the superior knowledge of the present could judge the inferiority of the past, without considering historical context. *Chapters 3 and 4 situate Draper and White in wider historiographic/polemical Anglo-American contexts, from the sixteenth-century Reformation to the late nineteenth century. Protestant attacks on Roman Catholic moral and theological corruption were adapted to nineteenth-century histories of religion and science, with science as the solvent that cleansed "true religion" of its irrational accretions. Ungureanu reviews other well-known Christian writers, including Edward Hitchcock, Asa Gray, Joseph Le Conte, and Minot Judson Savage, who sought to accommodate their religious beliefs to evolutionary theories and historical-critical approaches to the Bible. *Chapter 5 offers a fascinating portrait of Edward Livingston Youmans--the American editor with prominent publisher D. Appleton and Popular Science Monthly--and his role in promoting the conflict-reconciliation historiography of Draper and White and the scientific naturalism of Huxley, Herbert Spencer, and John Tyndall. *In chapter 6 and "Conclusions," Ungureanu surveys critics of Draper's and White's work, although he neglects some important Roman Catholic responses. He also carefully analyzes the "liberal Protestant" and "progressive" writers who praised and popularized the Draper-White perspectives. Ungureanu is excellent at showing how later writers--atheists, secularists, and freethinkers--not only blurred distinctions between "religion" and "theology" but also appropriated historical conflict narratives as ideological weapons against any form of Christian belief, indeed any form of religion whatsoever. Ultimately, Ungureanu concludes, the conflict-thesis-leading-to-reconciliation narrative failed. The histories of Draper and White were widely, but wrongly, seen as emphatically demonstrating the triumph of science over theology and religious faith, rather than showing the compatibility of science with a refined and redefined Christianity, as was their actual intention. *Draper's History of the Conflict, from the ancients to the moderns, suggested an impressive historical reading program, as did his publication of A History of the Intellectual Development of Europe (rev. ed., 2 vols., 1875 [1863]). But one looks in vain for footnotes and bibliographies to support his controversial claims. White's two-volume study, however, landed with full scholarly apparatus, including copious footnotes documenting his vivid accounts of science conquering theological belief across the centuries. What Ungureanu doesn't discuss is how shoddy White's scholarship could be: he cherrypicked and misread his primary and secondary sources. His citations were not always accurate, and his accounts were sometimes pure fiction. Despite Ungureanu's recovery of German sources behind White's understanding of history and religion, he does not cite Otto Zöckler's Geschichte der Beziehungen zwischen Theologie und Naturwissenschaft (2 vols., 1877-1879), which, as Bernard Ramm noted in The Christian View of Science and Scripture (1954), served as "a corrective" to White's history. *Ungureanu certainly knows, and refers to some of, the primary sources in the large literature of natural theology. I think he underplays the roles of Victorian natural theologies and theologies of nature in reflecting, mediating, criticizing, and rejecting conflict narratives. Ungureanu seems to assume readers' familiarity with the classic warfare historians. He could have provided more flavor and content by reproducing some of Draper's and White's melodramatic and misleading examples of good scientists supposedly conquering bad theologians. (One of my favorite overwrought quotations is from White, vol. 1, p. 70: "Darwin's Origin of Species had come into the theological world like a plough into an ant-hill. Everywhere those thus rudely awakened … swarmed forth angry and confused.") *Ungureanu's is relevant history. Nineteenth-century myth-laden histories of the "warfare between Christianity and science" provide the intellectual framework for influential twenty-first century "scientific" atheists who have built houses on sand, on misunderstandings of the long, complex and continuing relations between faith/practice/theology and the sciences. *This is fine scholarship, dense, detailed, and documented--with thirty-seven pages of endnotes and a select bibliography of fifty pages. It is also well written, with frequent pauses to review arguments and conclusions, and persuasive. Required reading for historians, this work should also interest nonspecialists curious about the complex origins of the infamous conflict thesis, its ideological uses, and the value of the history of religion for historians of science. *Reviewed by Paul Fayter, who taught the history of Victorian science and theology at the University of Toronto and York University, Toronto. He lives in Hamilton, ON.
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Hidayatulloh, Taufik, Elindra Yetti, and Hapidin. "Movement and Song Idiom Traditional to Enhance Early Mathematical Skills: Gelantram Audio-visual Learning Media." JPUD - Jurnal Pendidikan Usia Dini 14, no. 2 (November 30, 2020): 215–30. http://dx.doi.org/10.21009/jpud.142.02.
Full textAbstract:
Many studies have shown a link between being competent in early mathematics and achievement in school. Early math skills have the potential to be the best predictors of later performance in reading and mathematics. Movement and songs are activities that children like, making it easier for teachers to apply mathematical concepts through this method. This study aims to develop audio-visual learning media in the form of songs with a mixture of western and traditional musical idioms, accompanied by movements that represent some of the teaching of early mathematics concepts. The stages of developing the ADDIE model are the basis for launching new learning media products related to math and art, and also planting the nation's cultural arts from an early age. These instructional media products were analyzed by experts and tested for their effectiveness through experiments on five children aged 3-4 years. The qualitative data were analyzed using transcripts of field notes and observations and interpreted in a descriptive narrative. The quantitative data were analyzed using gain score statistics. The results showed that there was a significant increase in value for early mathematical understanding of the concepts of geometry, numbers and measurement through this learning medium. The results of the effectiveness test become the final basis of reference for revision and complement the shortcomings of this learning medium. Further research can be carried out to develop other mathematical concepts through motion and song learning media, and to create experiments with a wider sample.
Keywords: Early Mathematical Skills, Movement and Song Idiom Traditional, Audio-visual Learning Media
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