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Journal articles on the topic 'Yumiko'

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Published: 10 December 2022
Last updated: 29 January 2023

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1

Dobson, Hugo. "Masculinity and Japan’s Foreign Relations by Yumiko Mikanagi." Journal of Japanese Studies 40, no. 1 (2014): 259–62. http://dx.doi.org/10.1353/jjs.2014.0009.

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2

Benedek, Dezsõ. "Poetry of Ryuichi Tamura.Translated by Samuel Grolmes and Yumiko Tsumura." Translation Review 59, no. 1 (March 2000): 62–65. http://dx.doi.org/10.1080/07374836.2000.10524090.

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3

Endo, Masako. "Book Review: Masculinity and Japan’s Foreign Relations, written by Yumiko Mikanagi." Journal of American-East Asian Relations 21, no. 1 (March 12, 2014): 93–94. http://dx.doi.org/10.1163/18765610-02003004.

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4

Tomita, Ikuko. "Tamura Ryuichi Poems 1946–1998.by Samuel Grolmes and Tsumura Yumiko." Translation Review 64, no. 1 (September 2002): 90–95. http://dx.doi.org/10.1080/07374836.2002.10524113.

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5

Kamiya, Hiroyuki, Teruaki Ushijima, Chikako Ikeda, and Go Watanabe. "Gastroepiploic artery graft angiography via brachial approach using a Yumiko catheter." Catheterization and Cardiovascular Interventions 61, no. 3 (2004): 350–53. http://dx.doi.org/10.1002/ccd.10798.

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6

Ficet, Joël. "Masculinity and Japan’s Foreign Relations, Yumiko Mikanagi, 2011, Boulder, co, Lynne Rienner, 139 p." Études internationales 43, no. 4 (2012): 649. http://dx.doi.org/10.7202/1013363ar.

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7

Ramazzina Ghirardi, Ana Luiza. "LINGUAGEM MANGÁ E LINGUAGEM LITERÁRIA: NOVAS CONFIGURAÇÕES, NOVOS PRODUTOS MIDIÁTICOS." Scripta Uniandrade 19, no. 3 (December 11, 2021): 1–22. http://dx.doi.org/10.55391/2674-6085.2021.2215.

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Este artigo analisa a transposição midiática de uma narrativa em linguagem verbal, do século XIX para uma narrativa em linguagem multimodal do mangá contemporâneo. Para isso, tomam-se dois fragmentos do romance Madame Bovary (1873), de Gustave Flaubert, e realiza-se um cotejo com sua adaptação no mangá Madame Bovary (2013/1997), de Yumiko Igarashi. Considerando que a linguagem mangá prioriza o apelo imagético em seu sistema interno, o artigo sugere que o processo de reconstrução do tecido narrativo é desenvolvido através de traços simples e de uma simbologia característicos desse produto de mídia. O papel do receptor neste processo é aqui considerado crucial. Ele representa parte integrante e central do funcionamento da nova mídia que tece em suas teias estruturais pistas para a apreensão do novo produto.
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8

Andrew Hock Soon Ng. "Confronting the Modern: Kōbō Abe's The Box Man and Yumiko Kurahashi's "The Witch Mask"." Criticism 51, no. 2 (2010): 311–31. http://dx.doi.org/10.1353/crt.0.0103.

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9

Kim, Moo Hyun, Kwang Soo Cha, Hye Jin Kim, and Jong Seong Kim. "Bilateral selective internal mammary artery angiography via right radial approach: Clinical experience with newly designed Yumiko catheter." Catheterization and Cardiovascular Interventions 54, no. 1 (2001): 19–24. http://dx.doi.org/10.1002/ccd.1232.

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10

Ozawa, Terutomo. "Japan's Trade Policy: Action or Reaction?. By Yumiko Mikanagi. London and New York: Routledge, 1996. 163 pp. £40.00." Journal of Asian Studies 56, no. 4 (November 1997): 1103–5. http://dx.doi.org/10.2307/2658335.

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11

Shibamoto-Smith, Janet S. "Patrick Heinrich & Yumiko Ohara, Routledge handbook of Japanese sociolinguistics. London: Routledge, 2019. Pp. xxii, 464. Hb £190." Language in Society 49, no. 5 (July 9, 2020): 781–85. http://dx.doi.org/10.1017/s0047404520000238.

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12

Miwa, Yumiko. "An international comparative study of the influence of investment funds on enterprise management." Impact 2021, no. 3 (March 29, 2021): 41–43. http://dx.doi.org/10.21820/23987073.2021.3.41.

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In the world of business nowadays there is a focus on shareholders, and a lack of separation between ownership and management. Innovations in investment technology have led to a growth in the assets of institutional investors and an increased influence of investors. Indeed, many investors have assumed the role of 'speaking shareholder' for the companies in question. This is referred to as hedge fund activism, with once silent investors becoming shareholders and, as a result, individuals and hedge funds are able to dominate the activities of companies. From the late 1990s to the early 2000s this situation was centred around pension funds but now revolves around hedge funds. Professor Yumiko Miwa, Graduate School of Commerce, Meiji University, Japan, is conducting an international comparative study of the influence of investment funds on enterprise management. This research investigates anti-takeover measures, preferential treatments and addresses potential conflicts of interest. In other research, Miwa is working to address the stance taken by some companies that women are socially disadvantaged. The topic of this research is Women Working in the Capital Markets.
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13

Cahyadi, Anastasia, and Suzy Azeharie. "Penyingkapan Diri Pasangan Lesbian di Instagram (Studi Tentang Pandangan Generasi Z pada Akun @just.yumi)." Koneksi 6, no. 1 (March 2, 2022): 69. http://dx.doi.org/10.24912/kn.v6i1.15456.

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As social beings, humans have a desire to create interpersonal relationships and communication. Interpersonal communication is also often created in the use of social media. However, this can lead to the merging of private space with public space so that private activities can be disseminated, including sexual orientation. One person who dares to reveal her sexual orientation is Yumi. In the @just.yumi account, she shows a lesbian relationship with her girlfriend. For this reason, this study wants to know the views of Generation Z on self-disclosure of lesbian couples on Yumi’s Instagram account. The theory used in this research are interpersonal communication and self-disclosure. The author uses a qualitative research approach with a case study method. The research data were obtained through interviews with six sources and one expert resource, simple surveys, documentation and literature studies. The results showed that Generation Z didn’t mind with Yumi’s content. According to them it is a right and freedom of expression. However, the majority of generation Z also said that Yumi's content could have a negative impact on Instagram users.Sebagai makhluk sosial, manusia mempunyai keinginan untuk menciptakan hubungan dan komunikasi interpersonal. Komunikasi interpersonal ini juga sering tercipta dalam penggunaan media sosial. Namun hal ini dapat menyebabkan bersatunya ruang pribadi dengan ruang publik sehingga kegiatan yang bersifat pribadi dapat disebarluaskan, termasuk mengenai orientasi seksual. Salah satu orang yang berani menyingkapkan orientasi seksualnya ialah Yumi, dalam akun @just.yumi, di mana pemilik akun memperlihatkan hubungan lesbian dengan pasangannya. Untuk itu penelitian ini ingin mengetahui pandangan generasi Z pada penyingkapan diri pasangan lesbian dalam akun Instagram. Teori yang digunakan dalam penelitian ini adalah teori komunikasi interpersonal dan penyingkapan diri. Penulis menggunakan pendekatan penelitian kualitatif dengan metode studi kasus. Data hasil penelitian didapatkan melalui wawancara dengan enam narasumber dan satu narasumber ahli, survei sederhana, dokumentasi serta studi kepustakaan. Hasil penelitian menunjukkan bahwa generasi Z tidak mempermasalahkan konten Yumi karena dinilai sebagai hak dan kebebasan berekspresi. Namun mayoritas generasi Z juga mengatakan bahwa konten Yumi bisa berdampak negatif pada pengguna Instagram.
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14

Hadase, Mitsuyoshi, Tatsuya Kawasaki, Satoshi Asada, Tadaaki Kamitani, Shingo Kawasaki, and Hiroki Sugihara. "The YUMIKO™ catheter: a useful tool for angiography of the right internal mammary artery via a right brachial approach." International Journal of Cardiovascular Interventions 5, no. 2 (January 2003): 98–101. http://dx.doi.org/10.1080/14628840310003325.

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15

ENDO, Ginro, Hiromoto KOSHIKAWA, Naoko INOUE, Yumiko OHKOUCHI, and Yutaka TERASHIMA. "Application of Immobilization to E. coli Carrying Recombinant Plasmid Coding Dehalogenase Gene Hiromoto KOSHIKAWA, Naoko INOUE, Yumiko OHKOUCHI and Yutaka TERASHIMA." Doboku Gakkai Ronbunshu, no. 713 (2002): 193–96. http://dx.doi.org/10.2208/jscej.2002.713_193.

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16

Miyake, Yumiko, Teruo Inoue, Shigenori Morooka, Hiroshi Ando, and Minoru Shimizu. "A novel method for angiography of the left internal thoracic artery from a right arm approach using a YUMIKO-LITA catheter." American Journal of Cardiology 89, no. 8 (April 2002): 984–86. http://dx.doi.org/10.1016/s0002-9149(02)02254-3.

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17

Motegi, Yuji, Masaru Kawakami, Yosuke Watanabe, Jun Ogawa, Ajit Khosla, Nahin Islam Shiblee, and Hidemitsu Furukawa. "(Digital Presentation) 3D Chocolate Printing for Shape and Texture Control." ECS Meeting Abstracts MA2022-01, no. 57 (July 7, 2022): 2373. http://dx.doi.org/10.1149/ma2022-01572373mtgabs.

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Food 3D printing is expected to be a technology to create foods with different tastes and hardness depending on individual preferences and to solve the problem of food loss problems. In this study, we focus on the 3D printing of chocolate, whose product value is greatly affected by its appearance, entertainment and texture. Although 3D printers of chocolate are gradually appearing in the market, most of them only focus on the modeling of shape, and there are quite few printers that can form chocolate with designed texture. We develop a chocolate 3D printer using two chocolate materials. In addition to the syringe type extruder, we introduce the gear pump type extruder, which has a fine and stable extrusion. We 3d print chocolates with various internal structures using two chocolate materials and evaluate the differences in their textures by equipment measurement and by sensory tests. In addition, the melt-in-mouth feeling and the snappiness, which are important for the texture of chocolate, are investigated. In this presentation, we report the results of texture tests of black chocolate formed by a single syringe type 3D printer. References: Kodama, Mai, Yumiko Takita, Hideaki Tamate, Azusa Saito, Jin Gong, Masato Makino, Ajit Khosla, Masaru Kawakami, and Hidemitsu Furukawa. "Novel Soft Meals Developed by 3D Printing." Future Foods (2017): 161-181. Suzuki, Shunsuke, Jun Ogawa, Yosuke Watanabe, MD Nahin Islam Shiblee, Ajit Khosla, Masaru Kawakami, Jun Nango, and Hidemitsu Furukawa. "Texture Control of 3D Printing: Effect of Internal Structure of 3D Printed Foods on their Fracture Process in Compression." ECS Transactions 98, no. 13 (2020): 59. https://doi.org/10.1149/09813.0059ecst Rahman, Julkarnyne M. Habibur, MD Nahin Islam Shiblee, Kumkum Ahmed, Ajit Khosla, Masaru Kawakami, and Hidemitsu Furukawa. "Rheological and mechanical properties of edible gel materials for 3D food printing technology." Heliyon 6, no. 12 (2020): e05859. https://doi.org/10.1016/j.heliyon.2020.e05859
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18

Virginia, Prima. "Karakter Animasi Kecerdasan Emosional sebagai Media Komunikasi Interaksionisme Simbolik." Jurnal Komunikasi Global 11, no. 1 (June 28, 2022): 112–38. http://dx.doi.org/10.24815/jkg.v11i1.24717.

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Animasi tidak lagi sekedar menampilkan karikatur lucu berteknologi 3D, tapi juga karakter yang biasanya sulit dilihat kasat mata, yakni Emotional Intelligence atau kecerdasan emosional yang digambarkan di film animasi Inside Out dan drama Korea Selatan Yumi’s Cells. Karakter animasi kecerdasan emosional yang menghuni otak manusia mampu divisualisasikan saling berkomunikasi dan berinteraksi sehingga merepresentasikan konsep teori Interaksionisme Simbolik. Penelitian kualitatif dengan pendekatan analisis percakapan ini menawarkan hal baru tentang hubungan dan urutan proses terbentuknya komunikasi interaksionisme simbolik dari tiga konsep dalam teori interaksionisme simbolik dari dua versi yakni George Herbert Mead dan Herbert Blummer melalui interaksi karakter animasi dalam film Inside Out dan drama Yumi’s Cells. Hasil penelitian menunjukkan bahwa karakter animasi sel kecerdasan emosional yang digambarkan pada film Inside Out dan drama Yumi’s Cells mampu mendominasi representasi konsep interaksionis simbolik dengan memberikan visualisasi perasan dan emosi.Animation is not only about the presentation of 3D caricatures but also about something beyond the scope of aesthetics, such as Emotional Intelligence which is portrayed in the animated film Inside Out and South Korean drama series Yumi’s Cells. The animated emotional intelligence characters who ‘lives inside the human brain’ are visualized as communicating and interacting with each other, representing the concept of Symbolic Interactionism Theory. This qualitative research, with a conversation analysis approach, offered a new point about the relationship and sequence process in the formation of three concepts in symbolic interactionism theory from George Herbert Mead and Herbert Blummer through the interactions of the animated characters in the film Inside Out and drama Yumi’s Cells. The results of the study showed that the characters of animated cells with emotional intelligence in the animated films Inside Out and Yumi's Cells could dominate the representation of the symbolic interactionist concepts by visualizing emotions and feelings.
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19

Taupier, Richard. "The Resurgence of “Buddhist Government”: Tibetan-Mongolian Relations in the Modern World. By Yumiko Ishihama, with Makoto Tachibana, Ryosuke Kobayashi, and Takehiko Inoue. Osaka, Japan: Union Press, 2019. xiv, 242 pp. ISBN: 9784946428890 (cloth)." Journal of Asian Studies 78, no. 4 (November 2019): 906–7. http://dx.doi.org/10.1017/s0021911819001360.

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20

Wu, Lan. "Shinchō to Chibetto Bukkyō: bosatsuō to natta Kenryūtei [The Qing Dynasty and the Tibetan Buddhist World: The Qianlong Emperor Who Became a Buddhist King]. By Yumiko Ishihama. Tokyo: Waseda University Press, 2011. 330 pp. ¥7,000 (cloth)." Journal of Asian Studies 71, no. 4 (November 2012): 1133–35. http://dx.doi.org/10.1017/s0021911812001477.

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21

Umekita, K., Y. Hashiba, R. Kudou, S. Miyauchi, M. Kimura, M. Matsuda, C. Iwao, et al. "AB0268 HUMAN T-CELL LEUKAEMIA VIRUS TYPE 1 MAY INVALIDATE T-SPOT.TB RESULTS AMONG RHEUMATOID ARTHRITIS PATIENTS: A RETROSPECTIVE OBSERVATIONAL STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1432.1–1433. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1588.

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Background:In clinical rheumatology, interferon-γ release assays (IGRAs) have been reported as a useful diagnostic test for latent tuberculosis infection (LTBI) before beginning the administration of biologics such as anti-TNF therapies (1). CD4-positive T cells are the main target in Human T-cell leukaemia virus type 1 (HTLV-1) infection. Several reports suggest that the reaction of tuberculin skin test (TST) is attenuated in HTLV-1-positive individuals compared with that in HTLV-1-negative individuals (2). However, it remains unclear whether IGRAs are reliable for detecting TB infection among HTLV-1-positive RA patients.Objectives:The present study aimed to investigate the usefulness of the T-SPOT.TBassay in HTLV-1-positive RA patients. In addition, the association between the existence of IFN-γ producing T cells and HTLV-1 proviral loads (PVLs) in HTLV-1-positive RA patients was analysed on the basis of the T-SPOT.TBassay results.Methods:We reviewed the medical records of 75 HTLV-1-negative and 29 HTLV-1-positive RA patients were suspected cases of LTBI and evaluated using the T-SPOT.TBassay as a clinical practice from April 2012 to July 2019. The results of T-SPOT.TBwere collected from medical records, retrospectively. Peripheral blood samples were obtained from HTLV-1-positive RA patients for the analysis of HTLV-1 PVLs values. The study protocol was approved by the research ethics committees of our hospitals.Results:Approximately 55% of the HTLV-1-positive RA patients showed invalid results for the T-SPOT.TBassay (p < 0.0001); the cause of invalid results was a spot-forming count of >10 spots in the negative controls of the T-SPOT.TBassay among HTLV-1-positive RA patients. Among HTLV-1-positive RA patients, HTLV-1 PVL values were significantly higher in 16 patients who showed invalid results than in 13 patients who did not (p = 0.003). There were no between-group differences in female patient ratio, age, RA disease activity and therapeutic regimens. IFN-γ producing cells were detected in the peripheral blood of HTLV-1-positive RA patients without stimulation with TB-specific antigens.Conclusion:The incidence of invalid results for the T-SPOT.TBassay has been reported to be as low as 0.6% (3). The results of this assay for screening of LTBI in HTLV-1-positive RA patients should be interpreted with caution. Furthermore, our results show that an increase in IFN-γ producing T cell numbers due to HTLV-1 infection in RA patients may affect the pathogenesis of RA.References:[1]Iannone, F., et al.J. Rheumatol. Suppl.91, 41-46 (2014).[2]Tachibana, N., et al.Int. J. Cancer42, 829-831 (1988).[3]Rego, K., et al.Tuberculosis (Edinb.)108, 178-185 (2018).Acknowledgments:We would like to thank Dr Yuki Hashikura and Ms Yuki Kaseda of the University of Miyazaki for their technical support in this work. We would also like to acknowledge Ms Yumiko Kai at the Institute of Rheumatology, Zenjinkai Shimin-no-Mori Hospital, for her help in data management.A part this work was supported by a grant from the Practical Research Project for Rare/Intractable Diseases of the Japan Agency for Medical Research and Development (Grant No. JP19ek0109356), a Health and Labor Sciences Research Grant on Rare and Intractable Diseases from the Ministry of Health, Labor and Welfare of Japan (Grant No. 19FC1007), and a Grant-in-Aid for Clinical Research from Miyazaki University Hospital.Disclosure of Interests:Kunihiko Umekita Paid instructor for: Astellas Pharma Inc. Chugai Pharma Inc. Tanabe-Mitsubishi Pharma Inc., Speakers bureau: Bristol-Myers Squibb, Yayoi Hashiba: None declared, Risa Kudou: None declared, Shunichi Miyauchi: None declared, Masatoshi Kimura: None declared, Motohiro Matsuda: None declared, Chihiro Iwao: None declared, Yumi Kariya: None declared, Takeshi Kawaguchi: None declared, Katoko Takajo: None declared, Koushou Iwao: None declared, Yuuki Rikitake: None declared, Ichiro Takajo: None declared, Toshihiko Hidaka Paid instructor for: Astellas Pharma Inc. Chugai Pharma Inc. Tanabe-Mitsubishi Pharma Inc., Speakers bureau: Astellas Pharma Inc. Chugai Pharma Inc. Tanabe-Mitsubishi Pharma Inc., Akihiko Okayama: None declared
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22

Supendi, Supendi, Muhamad Rizki Maulana, and Samsul Fajar. "SISTEM YUMINA-BUMINA ALIRAN ATAS UNTUK PEMELIHARAAN IKAN BAUNG (Hemibagrus nemurus)." Buletin Teknik Litkayasa Akuakultur 19, no. 2 (November 1, 2021): 89. http://dx.doi.org/10.15578/blta.19.2.2021.89-92.

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Sistem yumina-bumina merupakan kombinasi teknis budidaya antara pemeliharaan ikan dengan tanaman sayur dan buah secara terpadu. Sistem ini mampu meningkatkan produktivitas baik pada ikan maupun tanamannya. Kelebihan lain dari sistem ini adalah dapat dilakukan di lahan yang terbatas dan hemat air. Tujuan kegiatan ini adalah mengaplikasikan teknik budidaya dengan sistem yumina-bumina aliran atas pada budidaya ikan baung bersama dengan tanaman pakcoy dan tomat. Metode kegiatan ini di mulai dari perakitan sistem yumina-bumina aliran atas, penyemaian tanaman, penanaman bibit tanaman, penebaran benih ikan, serta pemeliharaan sistem yumina-bumina, baik pada ikan, tanaman maupun sistem budidaya yang digunakan. Hasil kegiatan budidaya ikan dengan sistem yumina-bumina aliran atas mendapatkan jumlah panen ikan baung sebanyak 296 ekor, setara dengan sintasan sebesar 98,68% dengan biomassa ikan 4,56 kg. Selain mendapatkan ikan, juga didapatkan panen tanaman pakcoy sebanyak 3,6 kg dan tomat 4,6 kg. Secara umum, sistem yumina-bumina aliran atas ini berhasil memberikan keuntungan ganda kepada pembudidaya, yaitu berupa ikan baung, serta tanaman sayuran dan buah.
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23

Mustika, Indrayana, and Rani Rahmayani. "PEMANTAUAN KUALITAS AIR BOT (BAHAN ORGANIK TOTAL) DAN TAN (TOTAL AMONIAK NITROGEN) DALAM OPTIMALISASI TEKNOLOGI YUMINA-BUMINA." Buletin Teknik Litkayasa Akuakultur 15, no. 1 (September 27, 2017): 33. http://dx.doi.org/10.15578/blta.15.1.2017.33-36.

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Yumina-bumina adalah teknik budidaya yang memadukan antara sayuran (yu) dengan ikan (mina), dan buah-buahan (bu) dengan ikan (mina). Parameter kualitas air yang penting sistem yumina-bumina antara lain adalah BOT (bahan organik total) dan TAN (total amoniak nitrogen). Jika nilai parameter-parameter tersebut melampaui batas, dapat membahayakan kehidupan ikan yang dipelihara. Kegiatan ini bertujuan untuk memantau kualitas air pada parameter BOT dan TAN dalam kegiatan optimalisasi sistem yumina-bumina dengan unit proses pengendapan dan biofiltrasi yang berbeda yang dilakukan melalui sampling setiap dua minggu sekali selama delapan minggu. Hasil pengukuran tersebut menunjukkan bahwa nilai kadar BOT pada unit yumina-bumina yang memiliki satu buah bak pengendapan (unit A), satu buah bak pengendapan dan satu buah bak biofilter (unit B), serta dua buah bak pengendapan dan satu buah bak biofilter (unit C) mengalami kenaikan yang pada sampling keempat, sedangkan kadar TAN cenderung mengalami penurunan. Nilai kadar BOT dan TAN pada unit A cenderung lebih besar daripada unit B dan C, sedangkan unit C memiliki kadar BOT dan TAN yang terendah. Dengan demikian, kualitas air parameter BOT dan TAN pada unit yumina-bumina yang memiliki dua buah bak pengendapan dan satu buah bak biofilter lebih baik daripada unit yumina-bumina yang memiliki satu buah bak pengendapan dan satu buah bak biofilter maupun unit yumina-bumina yang hanya memiliki satu buah bak pengendapan.
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Supendi, Supendi, Muhammad Rizki Maulana, and Samsul Fajar. "PENAMBAHAN FILTER AIR PADA BUDIDAYA SISTEM YUMINA–BUMINA." Buletin Teknik Litkayasa Akuakultur 15, no. 1 (September 27, 2017): 15. http://dx.doi.org/10.15578/blta.15.1.2017.15-18.

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Yumina-bumina adalah teknik budidaya yang memadukan antara sayuran (yu) dengan ikan (mina) atau buah-buahan (bu) dengan ikan (mina). Sayuran dalam yumina adalah tanaman sayuran daun. Adapun bumina adalah yang menghasilkan tanaman sayuran buah. Pada kegiatan ini dilakukan uji sistem yumina–bumina melalui penambahan filter air dengan perlakuan A (1 bak pengendapan), B (1 bak pengendapan 1 bak biofilter), C (2 bak pengendapan 1 bak biofilter). Tujuan dari kegiatan ini adalah untuk mendapatkan informasi efektivitas penambahan filter air dalam sistem yumina-bumina terhadap produksi ikan dan tanaman. Berdasarkan hasil pengamatan, biomassa panen terbesar diperoleh dari perlakuan C yang menghasilkan ikan 108,85 kg; pakcoi 466,67 g; caisin 266,67 g; kailan 300 g; tomat 853,33 g; dan terong 255 g.
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25

Romanchuk, Oleksandr, and Vasyl Hanitkevych. "The influence of the Yumeiho therapy procedure on central hemodynamics and its assessment." Physical rehabilitation and recreational health technologies 7, no. 3 (September 30, 2022): 96–103. http://dx.doi.org/10.15391/prrht.2022-7.20.

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The purpose of the study was to determine changes in central hemodynamics under the influence of the Yumeiho therapy procedure and to develop criteria for their evaluation Material & Methods: 55 people who received Yumeiho therapy procedures at the "Yumeiho" center in Lviv were under supervision. Of them, 29 women aged 38.7 (32.0; 52.4) years and 26 men aged 35.8 (29.0; 46.6) years. The average age of the examinees was 37.5 (31.5; 47.2) years. All individuals had non-specific signs of manifestations of osteochondrosis of the spine. The methodology for the study of the indicators of the cardiovascular system involved the recording of blood pressure (BP) and heart rate (HR) in the supine position after 5 minutes of rest before the procedure, as well as after 5 minutes of rest in the supine position after the completion of the Yumeiho therapy Results: stroke volume (SV, cm3), cardiac output (CO, dm3), general peripheral vascular resistance (GPVR, dyn/s/cm−5), cardiac index (CI, dm3/m2) and stroke index (SI, cm3/m2) were calculated according to known formulas. The analysis of changes in hemodynamic parameters during 1014 procedures was carried out. It is shown that in the Yumeiho-therapy procedure, there is a significant decrease in SV, CO, CI, SI and an increase in GPRV, both in men and in women. There is a decrease in the kinetics of blood circulation to the hypokinetic level. Conclusions: the conducted study made it possible to establish that under the influence of Yumeiho therapy in patients there is a significant decrease in SV (cm3), CO (dm3), CI (dm3/m2), SI (cm3/m2), and a significant increase in GPRV (dyn/s/cm–5). According to the apriori data of the percentile analysis of changes in hemodynamic parameters, the limits of pronounced deviations, which may indicate an inadequate reaction of the body to the procedure, are established. That is, the obtained results can be useful during operational control of the effect of the Yumeiho therapy procedure on the patient's body. In the future, it is possible to consider the use of Yumeiho therapy in cardiac patients.
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Iwata, Hiroji, Aditya Bardia, Simon Lord, Hannah M. Linden, Mario Campone, Kenji Tamura, Kan Yonemori, et al. "Abstract CT517: Amcenestrant, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/HER2- advanced breast cancer (aBC): combined biomarker analyses from a Phase 1/2 study in postmenopausal women and a Phase 1 study in postmenopausal Japanese women." Cancer Research 82, no. 12_Supplement (June 15, 2022): CT517. http://dx.doi.org/10.1158/1538-7445.am2022-ct517.

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Abstract Background: Amcenestrant is an optimized oral SERD that has shown safety and clinical benefit in patients (pts) with wild-type (WT) and mutated ESR1 aBC. Here we provide a pooled analysis of biomarkers from two studies in heavily-pretreated, postmenopausal women with ER+/HER2- aBC. Methods: Pooled analysis included study data from AMEERA-1 (NCT03284957), in which pts received single-agent amcenestrant in dose escalation (20-600 mg QD or 300 mg BID) and dose expansion (400 mg QD), and from AMEERA-2 (NCT03816839), in which Japanese pts received single-agent amcenestrant at 400 mg QD or 300 mg BID. Mutational profiling of plasma circulating cell-free DNA was conducted by droplet digital polymerase chain reaction (ddPCR) for 12 pathogenic ESR1 mutations at baseline (BL) and on treatment (OT; Cycle 2, Day 28), and by next-generation sequencing (NGS; 77-gene panel) at BL and end of treatment (EOT). Clinical benefit (CB; complete response + partial response [PR] + stable disease ≥ 24 weeks) was assessed in pooled pts who received amcenestrant≥ 150 mg QD or BID. In tumor tissue, ER, progesterone receptor (PgR), Ki67 and Bcl-2 expression levels over time were assessed by immunohistochemistry; functional ER pathway activity was assessed by gene set variation analysis with RNA-seq data (ER activity score). Results: Among pts with data for ESR1 mutation status at BL (N = 80; ddPCR), 41 pts were WT and 39 pts had at least one ESR1 mutation, with D538G and Y537S the most prevalent. CB was observed in pts with both WT (13 pts) and mutated ESR1 (12 pts) at BL. The most frequent pathogenic mutations detected in pts (N = 79; NGS) at BL were ESR1 (49%), followed by PI3KCA (46%)and TP53 (33%). In response-evaluable pts with ESR1 mutational profiling at BL and OT (N = 40; ddPCR), 17 of 19 pts with ESR1 mutation at BL showed a decrease in ESR1 mutation allele frequency, independently of clinical benefit. Eight pts showed an increase (7/25 no CB and 1/15 CB). Among 17 pts with biopsies, pts with ER or PgR -/low (H-score: 0-3) at BL did not derive benefit from treatment. In the remaining patients with ER high (H-score ≥ 140), no difference between pts with and without CB was observed in ER, Bcl-2 or ER activity score, while pts with CB had a tendency for lower Ki67. ER and PgR decreased upon treatment independently of CB, while ER activity score and Ki67 mostly decreased in pts with CB and mostly increased in pts without CB. Conclusions: In postmenopausal women with ER+/HER2- aBC treated with single-agent amcenestrant, low Ki67 at BL and the pharmacodynamic decrease of Ki67 and ER activation score by amcenestrant trended toward an association with CB, whereas increase in ESR1 mutation allele frequency on treatment trended toward an association with lack of CB. Clinical benefit was observed in both pts with WT and mutated ESR1 at BL. Citation Format: Hiroji Iwata, Aditya Bardia, Simon Lord, Hannah M. Linden, Mario Campone, Kenji Tamura, Kan Yonemori, Toru Mukohara, Cécile Combeau, Nils Ternes, Dimitri Carene, Jeff Ming, Joon Sang Lee, Marina Celanovic, Anne-Laure Bauchet, Monsif Bouaboula, Tomoyuki Tanaka, Yumiko Kawabata, Sarat Chandarlapaty. Amcenestrant, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/HER2- advanced breast cancer (aBC): combined biomarker analyses from a Phase 1/2 study in postmenopausal women and a Phase 1 study in postmenopausal Japanese women [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr CT517.
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Tsujikawa, Takahiro, Kazuchika Ohno, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, et al. "Abstract 5210: Tumor immune characterization identifies age-stratified biomarkers for nivolumab in patients with head and neck squamous cell carcinoma: A nationwide collaborative study in Japan." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5210. http://dx.doi.org/10.1158/1538-7445.am2022-5210.

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Abstract Background: Biomarkers predicting therapeutic response to immunotherapy have been widely explored via monitoring the liquid and tissue-derived components. Increasing treatment options for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) mandates prediction of the therapeutic response of anti-PD-1 antibody alone as well as optimization of the treatment sequence. In view of improving biomarkers predicting the efficacy of immunotherapy for R/M HNSCC, we hypothesized that biomarkers can be personalized depending on clinicopathological backgrounds and treatment sequence. Methods: In this study, we retrospectively included formalin-fixed paraffin-embedded (FFPE) samples, peripheral blood cell counts at treatment, clinicopathological information, and outcome data for patients with R/M HNSCC receiving nivolumab across 22 institutions in Japan (N = 100). FFPE samples were subjected to 14-marker multiplex immunohistochemistry (IHC) and image cytometry analysis (Tsujikawa T et al. Cell Reports, 2017) to quantitatively evaluate CD8+ T cells, helper T cells, regulatory T cells, B cells, natural killer (NK) cells, macrophages, dendritic cells, CD66b+ granulocytes, mast cells, programmed death ligand 1 (PD-L1) and PD-1 expression in a single slide. Intratumoral and circulating immune cell frequencies were comparatively analyzed between responders (CR, n = 14; PR, n = 39) and non-responders (SD, n = 2; PD, n = 45). Results: Of 100 patients included, responders had significantly lower smoking and alcohol index, higher incidence of immune related adverse events, and higher PD-L1 expression in immune cells as well as PD-L1 combined positive score (CPS) than non-responders. Next, focusing on the history of prior therapy, stratified analysis revealed that the frequency of NK cells was associated with nivolumab response in patients with prior cetuximab use, but not in cetuximab-naïve status. Furthermore, stratified analysis by patient age revealed that nivolumab response was significantly associated with high CPS and lymphoid-inflamed profiles based on cell densities of nine immune cell lineages in the group aged 65 years or older, but not in the group under 65 years of age. On the contrary, the neutrophil/lymphocyte ratios (NLR) in peripheral blood counts at nivolumab treatment were significantly lower in responders (mean 4.96) than those in non-responders (mean 10.46) in the group under 65 years of age, but not in those over 65 years of age (7.41 versus 8.47). Conclusions: Using peripheral blood data and tumor tissue profiling stratified by patient age and prior treatment might provide better predictive biomarkers in nivolumab response to HNSCC. Further preclinical and clinical studies elucidating immune mechanisms in different patient backgrounds will be warranted. Citation Format: Takahiro Tsujikawa, Kazuchika Ohno, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Gaku Ohmura, Akihito Arai, Hiroshi Ogi, Saya Shibata, Yosuke Ariizumi, Akihisa Tasaki, Ryosuke Takahashi, Yumiko Tateishi, Hiroaki Kawabe, Sadakatsu Ikeda, Kei-ichi Morita, Tatsuhiko Tsunoda, Takumi Akashi, Morito Kurata, Issei Imoto, Yasushi Shimizu, Akihito Watanabe, Yukinori Asada, Ryuichi Hayashi, Yuki Saito, Hiroyuki Ozawa, Kiyoaki Tsukahara, Nobuhiko Oridate, Arata Horii, Takashi Maruo, Nobuhiro Hanai, Hidenori Inohara, Hiroshi Iwai, Takashi Fujii, Ken-ichi Nibu, Shigemichi Iwae, Tsutomu Ueda, Ryuji Yasumatsu, Hirohito Umeno, Muneyuki Masuda, Kyoko Itoh, Shigeru Hirano, Takahiro Asakage. Tumor immune characterization identifies age-stratified biomarkers for nivolumab in patients with head and neck squamous cell carcinoma: A nationwide collaborative study in Japan [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5210.
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Sakaeda, Kanako, Koji Kurose, Minoru Fukuda, Nanae Sugasaki, Akitoshi Kinoshita, Takashi Kitazaki, Masaaki Fukuda, et al. "Abstract A61: Development of automated immunoassay to detect serum biomarkers predicting response to immune checkpoint inhibitors in NSCLC." Cancer Immunology Research 10, no. 12_Supplement (December 1, 2022): A61. http://dx.doi.org/10.1158/2326-6074.tumimm22-a61.

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Abstract Introduction: Immunotherapy with immune checkpoint inhibitors (ICI) is the standard of care for advanced non-small-cell lung cancer (NSCLC) without driver gene alterations. However, survival benefits with ICI are limited to a small subset of NSCLC patients, and particularly ICI combinations with cytotoxic agents produce serious physical and large financial toxicities. Tumor PD-L1 expression levels/proportion score (TPS) are universally used as predictive biomarkers in ICI monotherapy response and outcomes. However, PD-L1/TPS assays are imperfect because of low analytical validity and reproducibility due to the visual-scoring system by pathologists. Therefore, additional biomarkers are urgently needed to predict ICI therapy response and outcomes. Recently, we reported that serum antibodies (Abs) against NY-ESO-1 and XAGE1 cancer-testis antigens were probably useful biomarkers in the prediction of clinical benefits with anti-PD-1 monotherapy for NSCLC (J Thorac Oncol, 2019). Additionally, we developed a fully automated immunoassay system (HISCLTM) to measure the Abs easily and rapidly (Sakai Y, et al. Clin Chim Acta 2021). In this study, we retrospectively examined whether the Abs measured by HISCLTM predict the clinical benefits with ICI monotherapy for NSCLC.Patients and Methods: Sera were obtained from controls of non-malignant lung diseases (n=75) and healthy subjects (n=100), and advanced NSCLC patients (n=263) to to determine a cutoff value in HISCLTM. In NSCLC patients analyzed here (n=78), sera were obtained before anti-PD-1 monotherapy with nivolumab in second-line or later settings. The serum NY-ESO-1/XAGE1 Abs were measured by HISCLTM, and we examined the relationships between the Abs levels, objective response rate (ORR), progression free survival (PFS), and overall survival (OS) after nivolumab monotherapy.Results: NY-ESO-1/XAGE1 Abs levels in NSCLC patients (n=263) were significantly higher than those in the controls (n=175). A cutoff value was determined as the Abs level of 10 SU/mL, calculated from the Abs values in the controls. The Abs (≥ 10 SU/mL) were detected in 21/78 (27%) of the NSCLC patients treated with nivolumab, and one patient had both NY-ESO-1 and XAGE1 Ab. An ORR was 62%, 16%, and 29% in the Abs-positives, the Abs-negatives, and overall, respectively. The Abs levels in responders were significantly higher than those in non-responders. The NSCLC patients with high-Abs values (≥ 10 SU/mL) had significantly better survivals with nivolumab monotherapy than those with low-Abs (PFS, HR 0.51, 95%CI 0.31-0.83, p &lt; 0.01; OS, HR 0.51, 95%CI 0.31-0.84, p &lt; 0.01). Interestingly, a few NSCLC patients with both high-Abs and driver genes responded well to nivolumab.Conclusions: Serum NY-ESO-1/XAGE1 Abs measured by HISCLTM are potential biomarkers that predict clinical benefits with anti-PD-1 monotherapy for NSCLC, even including driver genes. These findings warrant further biomarker studies using NY-ESO-1/XAGE1 Abs in clinical trial and practice of NSCLC immunotherapy. Citation Format: Kanako Sakaeda, Koji Kurose, Minoru Fukuda, Nanae Sugasaki, Akitoshi Kinoshita, Takashi Kitazaki, Masaaki Fukuda, Takeshi Masuda, Noboru Hattori, Yusuke Atarashi, Yumiko Sakai, Yasuhiro Irino, Mami Yamaki, Toshiyuki Sato, Hiroshi Mukae, Toru Oga, Mikio Oka. Development of automated immunoassay to detect serum biomarkers predicting response to immune checkpoint inhibitors in NSCLC [abstract]. In: Proceedings of the AACR Special Conference: Tumor Immunology and Immunotherapy; 2022 Oct 21-24; Boston, MA. Philadelphia (PA): AACR; Cancer Immunol Res 2022;10(12 Suppl):Abstract nr A61.
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Chen, Feng, Jin-Liang Feng, Hai-Ping Hu, and Ping Wang. "Mid-Holocene palaeohydrochemistry and palaeohydrology of Yamdrok Yumtso, southern Tibetan Plateau, reconstructed from δ18O and δ13C of fossil shells of the gastropod Radix auricularia." Holocene 30, no. 12 (August 18, 2020): 1741–51. http://dx.doi.org/10.1177/0959683620950426.

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Palaeohydrochemical and palaeohydrological changes of lakes have seldom been reconstructed from the fossil shells of the gasropod Radix auricularia, which is a new, and potentially high-resolution environnmental archive. We conducted a geochemical and stable isotope study of the shells of Radix from the exposed fluvio-lacustrine sediments near Lake Yamdrok Yumtso in the southern Tibetan Plateau. Our aims were to determine the sedimentary environment, palaeo-lake hydrochemistry and hydrological status. AMS 14C and OSL dating indicates that a lake-level stage of Yamdrok Yumtso higher than that of today occurred during ~4.7–1.2 cal. kyr BP. Results of Sr/Ca, δ13C and δ18O analysis of the fossil shells of Radix auricularia indicate that the lake-level fluctuations were mainly controlled by changes of the Indian Summer Monsoon; decreasing evaporation during the mid- to late-Holocene was also responsible. In addition, based on the geochemical relationship between Radix sp. shells and the ambient water in lakes, the values of δ18OPalaeo-water and Sr/CaPalaeo-water reconstructed using the fossil shells of Radix auricularia are −8.2‰ to −5.1‰ and 0.0012 to 0.0057, respectively. Further, based on the values of δ18Oshell, together with geomorphological evidence, we infer that Yamdrok Yumtso was a closed lake system, and we estimate its possible extent during the interval of high lake-level. In addition, we speculate that the water level of Yamdrok Yumtso at this time exceeded 4448.9 m a.s.l., but was less than 4451 m a.s.l., and that the major separation of various components of the Yamdrok Yumtso system occurred after 1.2 kyr BP.
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Mehraban, Z., and L. Alizadeh. "114 YUMEIHO THERAPY AND MENOPAUSE." Maturitas 71 (March 2012): S54. http://dx.doi.org/10.1016/s0378-5122(12)70225-6.

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Pratama, Aditya, Rakhmawati Oktavianna, and Sulistiyani Sulistiyani. "KONTRIBUSI KOLAM IKAN "YUMINA BUMINA" SEBAGAI UPAYA PENINGKATAN PENDAPATAN KELUARGA DIDESA JAMPANG BOGOR." Economy Deposit Journal (E-DJ) 1, no. 2 (December 28, 2019): 74–80. http://dx.doi.org/10.36090/e-dj.v1i2.572.

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Desa Jampang adalah salah satu desa dalam wilayah kecamatan Kemang dan masuk dalam kabupaten Bogor. Desa Jampang dinobatkan sebagai desa penghasil budidaya ikan terbesar di Kabupaten Bogor. Budidaya ikan merupakan sumber mata pencarian terbesar bagi penduduk Desa Jampang. Banyaknya masyarakat sebagai pelaku budidaya ikan air tawar mampu menghasilkan beberapa inovasi dalam penggunaan kolam yang diberi nama kolam YUMINA (sayur dan ikan) BUMINA (buah dan ikan). Kolam YUMINA BUMINA merupakan kolam yang tidak hanya menghasilkan ikan air tawar tetapi juga mampu menghasilkan sayuran dan buah-buahan tertentu dengan memanfaatkan tempat budidaya ikan air tawar. Adapun rumusan masalah dalam penelitian ini yaitu: Bagaimana kontribusi kolam ikan "YUMINA BUMINA" sebagai upaya peningkatan pendapatan keluarga di Desa Jampang Bogor?. Tujuan penelitian untuk menganalisis kontribusi kolam ikan "YUMINA BUMINA" sebagai upaya peningkatan pendapatan keluarga di Desa Jampang Bogor. Metode analisis data pada penelitian ini memiliki beberapa tahapan yang harus terpenuhi. Tahapan yang pertama adalah tahap observasi, dengan tahapan ini merupakan tahap pengumpulan data dengan menggunakan teknik observasi,teknik wawancara dan dokumentasi. Tahap yang kedua ialah tahap reduksi data,dengan tahap ini sebagai proses seleksi dan pemfokusan data yang ada dilapangan. Tahap ke tiga yaitu tahap penyajian data, tahapan ini merangkai semua informasi yang telah dikumpulkan. Tahap ke empat yaitu tahap penarikan kesimpulan, tahap ini merupakan tahap terakhir daari analisis data. Lokasi penelitian ini berada pada Desa Jampang, Bogor dan sampel penelitian ini adalah Para pembudidaya ikan kelompok pintu air di Desa Jampang, Bogor.
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Sunaryo, Ade, and Yenni Nuraini. "Diseminasi teknologi budidaya Yumina Bumina Ikan Herbivora mendukung ketahanan pangan masyarakat Desa Cisaladah Kecamatan Cigombong Kabupaten Bogor, Jawa Barat." Unri Conference Series: Community Engagement 3 (November 18, 2021): 340–45. http://dx.doi.org/10.31258/unricsce.3.340-345.

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Dissemination is one form of activity to obtain information aimed at individuals or target groups who meet the qualifications. This activity aims to apply the dissemination of aquaculture technology with community nutrition self-help activities through side dishes and vegetables produced from the Yumina-Bumina fish farming method. In addition, the existence of Yumina-Bumina cultivation technology is expected to provide convenience for the community, especially stunting areas, to increase their livelihoods by carrying out fish cultivation activities that do not require a large place and a lot of water. This activity was carried out in three groups of fish farmers in Cisaladah Village, Cigombong District, Bogor Regency. The stages of activities carried out in community service activities include socialization, training and mentoring. The dissemination activities of Yumina-Bumina aquaculture technology products to the community that have been carried out have been carried out thanks to the collaboration of the service team, village officials and fish cultivator groups in creating and developing a productive herbivorous fish farming business, so as to encourage community economic improvement
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Erdal ÖZAYDIN, Tahir POLAT, and Mustafa OKANT. "Bazı Buğdaygil Çim Türü ve Çeşitlerinin Adaptasyonları İle Çim Alan Özelliklerinin Belirlenmesi." ISPEC Journal of Agricultural Sciences 5, no. 1 (March 9, 2021): 48–56. http://dx.doi.org/10.46291/ispecjasvol5iss1pp48-56.

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Bu araştırma Şanlıurfa'da 2015-2016 yaz yetiştirme sezonunda, Harran Üniversitesi Osman Bey yerleşkesi Ziraat Fakültesi araştırma ve uygulama alanında yürütülmüştür. Araştırmada; kamışsı yumak (Festuca arundinaceae), İngiliz çimi (Lolium perenne), rizomsuz kırmızı yumak (Festuca rubra L. subsp. Commutate), rizomlu kırmızı yumak (Festuca rubra L. subsp. rubra), koyun yumağı (Festuca ovina), çayır salkım otu (Poa pratensis) materyal olarak kullanılmış, tesadüf blokları deneme desenine göre 3 tekerrürlü olacak şekilde kurulmuştur. Bu çalışmada; çim yaş ot verimi (kg/da), çim kuru ot verimi (kg/da), çıkış hızı (gün), kışa dayanıklılık (1-9), kaplama hızı (gün), kaplama derecesi (%), yaprak dokusu (1-9), kardeş sayısı (1-5) ve seyrekleşme derecesi (1-9) gibi karakterler incelenmiştir. Deneme bulgularına göre; Şanlıurfa ekolojik şartları için önerilebilecek sıcak mevsim çim tür çeşitlerinin pek çok özellik açısından kamışsı yumak (Festuca arundinaceae) Golden Gate çeşidinin kullanılması uygun olacaktır.
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이청. "A Study of Joung Yumi’s Picture Books." Korean Journal of Arts Studies ll, no. 22 (December 2018): 277–99. http://dx.doi.org/10.20976/kjas.2018..22.012.

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Spolsky, Bernard. "Li Yuming (2015): Language Planning in China." Language Policy 18, no. 1 (April 21, 2018): 155–57. http://dx.doi.org/10.1007/s10993-018-9466-6.

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Kondo, Y., Y. Kaneko, S. Saito, Y. Ohta, K. Sakata, Y. Inoue, C. Takahashi, K. Hiramoto, J. Inamo, and T. Takeuchi. "SAT0113 DISCORDANCE OF CLINICAL REMISSION AND IMAGING REMISSION BY ULTRASONOGRAPHY IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH BIOLOGIC AGENTS." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 990.2–990. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5048.

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Background:Residual synovitis can be detected by sensitive modalities such as ultrasonography in patients with rheumatoid arthritis in clinical remission. On the other hand, a previous study has shown that ultrasound-guided treatment provides modest benefit compared to a conventional strategy aiming clinical remission in early patients. It is still unclear how discordant clinical remission is from imaging remission by ultrasonography in patients treated with biologic agentsObjectives:To clarify the discordance between clinical remission and imaging remission in patients with rheumatoid arthritis treated with biologic agents.Methods:Patients with rheumatoid arthritis who were treated with biologic agents and in clinical remission defined as disease activity score for 28 joints (DAS28)<2.6 were enrolled. All patients were performed comprehensive ultrasound examination of 44 joints as well as physical examinations. Ultrasound images of gray scale (GS) and power doppler (PD) were evaluated with a semi-quantitative score of 0-3. Imaging remission with ultrasound was defined as no PD signal detected in any joints. Clinical information was collected from their medical charts.Results:A total of 41 patients were enrolled with 22 patients treated with tumor necrosis factor (TNF)-α inhibitors and 19 with interleukin (IL)-6 inhibitors. The mean age, female ratio, the mean disease duration, and the mean duration of clinical remission were 60 years old, 87%, 5.1 years and 11.5 years. The imaging remission by ultrasonography was observed only in 51.2 %. When patients were divided according to biologic agents, baseline characteristics including median age, disease duration and clinically remission duration were comparable between both groups, while the rates of seropositivity and the stage of radiological progression was higher in IL-6 group (seropositivity, p=0.04; radiological progression, p=0.02). The mean DAS28 was 1.93 in the TNFα group and 1.02 in the IL-6 group. The discordance of clinical remission and imaging remission was observed in 28.6% of the TNFα group and 71.4% of the IL-6 group (p=0.03). The residual synovitis scores of GS and PD in 44 joints were significantly lower in the TNFα than the IL-6 group (GS, 1.1±1.8 vs 4.7 ± 4.6, p<0.01; PD, 0.6 ± 1.3 vs 3.3 ± 3.5, p<0.01, respectively). A receiver operating characteristic curve demonstrated an optimal score of DAS28 that discriminated imaging remission as 1.89 in the TNFα group and 1.25 in the IL-6 group.Conclusion:Our results showed that there was substantial discordance between clinical remission and imaging remission, especially in the patients treated with IL-6 inhibitors. In patients treated with biologic agents, clinical remission should be assessed more stringently than the usual 2.6, and ulltrasound-guided management may be useful.References:[1]Smolen JS, et al. Ann Rheum Dis 2020;0:1–15.[2]Iwamoto T, et al. Arthritis Care Res (Hoboken). 2014;66(10):1576-81[3]Tanaka Y. Ann Rheum Dis 2010;69:1286 –91[4]Kaneko Y, et al. Ann Rheum Dis 2018;77:1268–1275[5]Brown AK, et al. Arthritis Rheum 2008;58: 2958 – 67.Acknowledgments:We would like to thank Harumi Kondo for their assistance.Disclosure of Interests:Yasushi Kondo: None declared, Yuko Kaneko Speakers bureau: Dr. Kaneko reports personal fees from AbbVie, personal fees from Astellas, personal fees from Ayumi, personal fees from Bristol-Myers Squibb, personal fees from Chugai, personal fees from Eisai, personal fees from Eli Lilly, personal fees from Hisamitsu, personal fees from Jansen, personal fees from Kissei, personal fees from Pfizer, personal fees from Sanofi, personal fees from Takeda, personal fees from Tanabe-Mitsubishi, personal fees from UCB, Shuntaro Saito: None declared, Yuichiro Ohta: None declared, Komei Sakata: None declared, Yumiko Inoue: None declared, Chihiro Takahashi: None declared, Kazuoto Hiramoto: None declared, Jun Inamo: None declared, Tsutomu Takeuchi Grant/research support from: Eisai Co., Ltd, Astellas Pharma Inc., AbbVie GK, Asahi Kasei Pharma Corporation, Nippon Kayaku Co., Ltd, Takeda Pharmaceutical Company Ltd, UCB Pharma, Shionogi & Co., Ltd., Mitsubishi-Tanabe Pharma Corp., Daiichi Sankyo Co., Ltd., Chugai Pharmaceutical Co. Ltd., Consultant of: Chugai Pharmaceutical Co Ltd, Astellas Pharma Inc., Eli Lilly Japan KK, Speakers bureau: AbbVie GK, Eisai Co., Ltd, Mitsubishi-Tanabe Pharma Corporation, Chugai Pharmaceutical Co Ltd, Bristol-Myers Squibb Company, AYUMI Pharmaceutical Corp., Eisai Co., Ltd, Daiichi Sankyo Co., Ltd., Gilead Sciences, Inc., Novartis Pharma K.K., Pfizer Japan Inc., Sanofi K.K., Dainippon Sumitomo Co., Ltd.
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ERTEKİN, İbrahim, Şaban YILMAZ, and Ersin CAN. "Determination of Responses to Salt Stress of Some Fescue (Festuca spp.) Species at Germination and Seedling Stages." Mustafa Kemal Üniversitesi Tarım Bilimleri Dergisi 27, no. 2 (July 26, 2022): 266–71. http://dx.doi.org/10.37908/mkutbd.1087363.

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Amaç: Bu çalışma farklı tuz dozları (kontorl/0, 50 mM, 100 mM, 150 mM ve 200 mM) altında bazı çim türlerinin (Festuca arundinaceae L. (kamışsı yumak), Festuca rubra L. subsp. rubra (rizomlu kırmızı yumak) ve Festuca rubra L. subsp. commutata (rizomsuz kırmızı yumak)) performaslarını belirlemek için yürütülmüştür. Yöntem ve Bulgular: Çalışmada farklı tuz dozlarını oluşturmak için NaCl2 kullanılmıştır. Tuz dozlarına göre hazırlanan solüsyonlar çim türlerinin çimlenme ortamına 8 mL olarak ilave edilmiş ve çim türleri 10 gün boyunca iklim dolabında çimlenme ve fide gelişimine bırakılmıştır. Bu sürenin sonunda çimlenme oranı, çimlenme indeksi, ortalama çimlenme süresi, sürgün ve kök uzunluğu ve fide yaş ağırlığı özellikleri incelenmiştir. Çim türlerinin tuz dozlarından çimlenme oranı, çimlenme indeksi ve ortalama çimlenme süresi etkilenmezken, sürgün ve kök uzunluğu ve fide yaş ağırlığı özellikleri etkilenmiştir. Genel Yorum: Elde edilen sonuçlara göre çim türlerinin farklı tuz dozlarındaki fide gelişimi özelliklerinin farklılık gösterdiği sonucuna varılmıştır. Çalışmada kullanılan Festuca rubra L. subsp. rubra (rizomlu kırmızı yumak) türünün diğer türlere kıyasla tuz stresine karşı daha toleransı olduğu belirlenmiştir. Çalışmanın Önemi ve Etkisi: Festuca cinsine ait çim türlerin farklı tuz stresi altında incelenmesi, yeşil alan tesis etmek için yapılan çalışmalarda özelliklede tuzluluk sıkıntısı olan bölgeler için yol gösterici olması amaçlanmıştır. Ayrıca bu çalışma yapılacak bilimsel çalışmalara kaynak olma niteliği taşımaktadır.
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38

Human Rights Case Digest, Editors. "Yumak and Sadak v. Turkey." Human Rights Case Digest 18, no. 11-12 (October 3, 2008): 1107–10. http://dx.doi.org/10.1163/15718131-90000064.

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39

Gómez Sánchez, Julián Andrés, Orlando Posada Orrego, and Jenny Marcela Ramírez García. "Análisis de los tributos e ingresos verdes del municipio de Yumbo - Valle del Cauca, Colombia, evaluados desde la perspectiva de la política pública ambiental y la política fiscal." Cuadernos de Contabilidad 21 (December 19, 2020): 1–11. http://dx.doi.org/10.11144/javeriana.cc21.ativ.

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El objetivo del presente artículo consiste en explicar la función paliativa de los tributos verdes en relación con el deterioro ambiental, tomando como caso de análisis el municipio de Yumbo, Valle del Cauca. La pregunta que guía la investigación es: ¿la ejecución de políticas públicas en materia ambiental y fiscal permite que las autoridades y ciudadanía del municipio de Yumbo conviertan el manejo de los tributos e ingresos medioambientales en una alternativa que mitigue la contaminación ambiental durante el período 2015 al 2019? Se utilizó una metodología de carácter cualitativo, descriptivo y documental, en correlación con los métodos de investigación deductivo y analítico. Se determinó que el municipio de Yumbo destinó un promedio anual de 1,36% del total de su presupuesto a la mitigación de la contaminación ambiental. Se concluye que los tributos verdes creados para la financiación de la gestión del medio ambiente son insuficientes para disminuir la contaminación y, en consecuencia, el país está lejos de cumplir los Objetivos de Desarrollo Sostenible
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40

Clerici, Nathen. "Yumeno Kyūsaku and the Spirit of the Local." Japanese Studies 39, no. 1 (January 2, 2019): 75–94. http://dx.doi.org/10.1080/10371397.2019.1576295.

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41

Saby, Brianna. "The LettersBy Kazumi Yumoto, Translated by Cathy Hirano." Journal of Intergenerational Relationships 8, no. 4 (November 24, 2010): 420. http://dx.doi.org/10.1080/15350770.2010.521082.

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42

Biskop, S., F. Maussion, P. Krause, and M. Fink. "Differences in the water-balance components of four lakes in the southern-central Tibetan Plateau." Hydrology and Earth System Sciences 20, no. 1 (January 18, 2016): 209–25. http://dx.doi.org/10.5194/hess-20-209-2016.

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Abstract. The contrasting patterns of lake-level fluctuations across the Tibetan Plateau (TP) are indicators of differences in the water balance over the TP. However, little is known about the key hydrological factors controlling this variability. The purpose of this study is to contribute to a more quantitative understanding of these factors for four selected lakes in the southern-central part of the TP: Nam Co and Tangra Yumco (increasing water levels), and Mapam Yumco and Paiku Co (stable or slightly decreasing water levels). We present the results of an integrated approach combining hydrological modeling, atmospheric-model output and remote-sensing data. The J2000g hydrological model was adapted and extended according to the specific characteristics of closed-lake basins on the TP and driven with High Asia Refined analysis (HAR) data at 10 km resolution for the period 2001–2010. Differences in the mean annual water balances among the four basins are primarily related to higher precipitation totals and attributed runoff generation in the Nam Co and Tangra Yumco basins. Precipitation and associated runoff are the main driving forces for inter-annual lake variations. The glacier-meltwater contribution to the total basin runoff volume (between 14 and 30 % averaged over the 10-year period) plays a less important role compared to runoff generation from rainfall and snowmelt in non-glacierized land areas. Nevertheless, using a hypothetical ice-free scenario in the hydrological model, we indicate that ice-melt water constitutes an important water-supply component for Mapam Yumco and Paiku Co, in order to maintain a state close to equilibrium, whereas the water balance in the Nam Co and Tangra Yumco basins remains positive under ice-free conditions. These results highlight the benefits of linking hydrological modeling with atmospheric-model output and satellite-derived data, and the presented approach can be readily transferred to other data-scarce closed lake basins, opening new directions of research. Future work should go towards a better assessment of the model-chain uncertainties, especially in this region where observation data are scarce.
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43

Jun, Ji Hae, Jung Hyun Kwon, Eun Young Nam, Kyeong Ho Chung, Ik Koo Yun, Seok Kyu Yun, Yong Bum Kwack, Sung Jong Kim, and Sang Jo Kang. "‘Yumi’ Peach." HortScience 48, no. 11 (November 2013): 1416–17. http://dx.doi.org/10.21273/hortsci.48.11.1416.

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44

Aoyama, Tomoko. "Dismembered but Not Disembodied: The Girl'sBodyin Yumeno Kyūsaku's Stories." Asian Studies Review 32, no. 3 (September 2008): 307–21. http://dx.doi.org/10.1080/10357820802294115.

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45

Biskop, S., F. Maussion, P. Krause, and M. Fink. "What are the key drivers of regional differences in the water balance on the Tibetan Plateau?" Hydrology and Earth System Sciences Discussions 12, no. 4 (April 29, 2015): 4271–314. http://dx.doi.org/10.5194/hessd-12-4271-2015.

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Abstract. Lake-level fluctuations in closed basins on the Tibetan Plateau (TP) indicate climate-induced changes in the regional water balance. However, little is known about the region's key hydrological parameters, hampering the interpretation of these changes. The purpose of this study is to contribute to a more quantitative understanding of these controls. Four lakes in the south-central part of the TP were selected to analyze the spatiotemporal variations of water-balance components: Nam Co and Tangra Yumco (indicating increasing water levels), and Mapam Yumco and Paiku Co (indicating stable or slightly decreasing water levels). We present the results of an integrated approach combining hydrological modeling, atmospheric-model output and remote-sensing data. The hydrological model J2000g was adapted and extended according to the specific characteristics of closed lake basins on the TP and driven with "High Asia Refined analysis (HAR)" data at 10 km resolution for the period 2001–2010. Our results reveal that because of the small portion of glacier areas (1 to 7% of the total basin area) the contribution of glacier melt water accounts for only 14–30% of total runoff during the study period. Precipitation is found to be the principal factor controlling the water-balance in the four studied basins. The positive water balance in the Nam Co and Tangra Yumco basins was primarily related to larger precipitation amounts and thus higher runoff rates in comparison with the Paiku Co and Mapam Yumco basins. This study highlights the benefits of combining atmospheric and hydrological modeling. The presented approach can be readily transferred to other ungauged lake basins on the TP, opening new directions of research. Future work should go towards increasing the atmospheric model's spatial resolution and a better assessment of the model-chain uncertainties, especially in this region where observational data is missing.
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46

Wada, Akinori. "Experience Bali in Japan: A Short Trip to Nasu Highland." Bali Tourism Journal 4, no. 3 (December 5, 2020): 49–53. http://dx.doi.org/10.36675/btj.v4i3.49.

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COVID-19 outbreak around the world made overseas travel almost impossible. Thus, for this summer holiday, Nasu may be opted as destination to spend freetime with family. Located in the northeast of Tochigi prefecture, Nasu is a rural town set in a vast mountain range. The area is famous for its attractions such as onsen, themed park and winter sports. There is also a historical sightseeing Sessho-seki, Nasu Yumoto Onsen, and Imperial villa. Those who wish to experience overseas experience may visit the mini theme park of the Asian old bazaar, located on Nasu Road in Tsumujiga-daira Yumoto, Nasu Town. There we can find shopping complexes with Asian themes such as Vietnam, India, Nepal, Thailand and Bali. Ubudo Restaurant, a restaurant decorated with Balinese architecture, offers a variety of Balinese culinary specialties. The Balinese vibe is strongly-felt right after entering the restaurant's Candi Bentar gate, which perfected the dining experience in Bali. The visitor may also visit many favorite spots such as Nasu ropeway, Minamigaoka Bokujo, the Monkey Park, the Museum of Cars, the Teddy Bear Museum, and the Animal Kingdom tourist park that should not be missed.
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47

Kun, Tara. "Missing: Yumi Itō." Massachusetts Review 60, no. 2 (2019): 355–71. http://dx.doi.org/10.1353/mar.2019.0055.

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48

Clerici, Nathen. "Madness, mystery and abnormality in the writing of Yumeno Kyūsaku." Japan Forum 28, no. 4 (March 18, 2016): 439–64. http://dx.doi.org/10.1080/09555803.2016.1147484.

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49

Zhou, Yang, Wei Leng, and Zhifeng Du. "Professor Yumao Du’s Experience in Treating Chronic Nephritis." Proceedings of Anticancer Research 5, no. 4 (July 29, 2021): 30–33. http://dx.doi.org/10.26689/par.v5i4.2317.

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Chronic nephritis is a common clinical kidney disease, with insidious onset and long course, which can eventually develop into chronic renal failure. In Chinese medicine, it belongs to the categories of “edema,” “back pain,” “deficiency,” and “vertigo.” Professor Du Yumao is a well-known Chinese medicine doctor and a well-known nephropathy expert in China. He has rich clinical experience and unique insights into the treatment of chronic nephritis. He believes that insufficient kidney yin is the key to this disease, and water dampness and blood stasis are important pathological factors. Appropriate change of method according to the situation and flexible use of medicine often lead to good clinical outcomes.
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50

GÜL, İsmail. "Diyarbakır Koşullarında Bazı Yumak Türlerinin Çim Alan Performansları." Journal of Agricultural Faculty of Gaziosmanpasa University 32, no. 2015-1 (January 1, 2015): 1–9. http://dx.doi.org/10.13002/jafag829.

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