Relevant bibliographies by topics / Xiong and guo model / Journal articles

Journal articles on the topic 'Xiong and guo model'

To see the other types of publications on this topic, follow the link: Xiong and guo model.
Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Xiong and guo model.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Cai, Sui Xiong, Ning Ma, Xiaozhu Wang, Jie Ma, Mingchuan Guo, Ruiyu Zhou, Lan Liu, Chih-Yi Hsieh, and Ye Edward Tian. "Abstract 1051: Combination of senaparib with temozolomide for the treatment of cancer." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1051. http://dx.doi.org/10.1158/1538-7445.am2022-1051.

Full text
Abstract:
Abstract Poly (ADP-ribose) polymerase (PARP) is a critical enzyme for DNA repair and PARP inhibitors have been found to be efficacious against cancers with defects in DNA repair pathways such as with BRCA mutations. In addition, in vitro and in vivo studies have found that for PARP inhibitors with good trapping activity, combination with temozolomide (TMZ) produced the best synergetic effects among different types of chemotherapies. Several clinical combination studies of PARP inhibitors with TMZ have been reported, such as the combination of olaparib with TMZ in small cell lung cancer (SCLC). In this presentation, we will report in vitro and in vivo studies of PARP inhibitor senaparib (IMP4297) in combination with TMZ. Synergetic effects were observed when senaparib was combined with TMZ in vitro against human SCLC NCI-H209 cells. In vivo studies of high-dose senaparib in combination with low-dose TMZ once a day continuously in human SCLC NCI-H209 xenograft model was found to be highly synergetic and well tolerated. A clinical study of senaparib in combination with TMZ in patients with advanced solid tumors and SCLC is ongoing (ClinicalTrials.gov Identifier: NCT04434482). Citation Format: Sui Xiong Cai, Ning Ma, Xiaozhu Wang, Jie Ma, Mingchuan Guo, Ruiyu Zhou, Lan Liu, Chih-Yi Hsieh, Ye Edward Tian. Combination of senaparib with temozolomide for the treatment of cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1051.
APA, Harvard, Vancouver, ISO, and other styles
2

Cai, Sui Xiong, Ning Ma, Xiaozhu Wang, Yangzhen Jiang, Mingchuan Guo, Chih-Yi Hsieh, and Ye Edward Tian. "Abstract 1399: Discovery and development of PARP inhibitor senaparib." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1399. http://dx.doi.org/10.1158/1538-7445.am2022-1399.

Full text
Abstract:
Abstract Poly (ADP-ribose) polymerase (PARP) is a key enzyme for DNA repair. PARP inhibitors have been shown to be effective against cancers with DNA repair defects, such as with BRCA1 or BRCA2 mutations. Several PARP inhibitors, including olaparib, rucaparib, niraparib, talazoparib, fluzoparib and pamiparib have been approved for the treatment of several types of cancer. In this presentation, we will report our discovery and development of senaparib (IMP4297) as a potent PARP inhibitor. We will present studies led to the identification of senaparib as a clinical candidate, as well as IND enabling in vitro and in vivo characterization of senaparib. Preclinical data indicated that senaparib had a wide therapeutic window (single agent effective dose of 2.5-21 mg/kg QD, in a BRCA1 mutated MDA-MB-436 human breast cancer xenograft model), which was confirmed in clinical studies (effective dose of 20-120 mg QD, and no DLT was found up to 150 mg QD). Senaparib is currently in several phase I/II, phase II and phase III clinical studies for the treatment of multiple tumor types either as single agent or in combination with temozolomide (TMZ). The most advanced study of senaparib is a phase III study as maintenance therapy in platinum-sensitive advanced ovarian cancer patients following first-line chemotherapy (ClinicalTrials.gov Identifier: NCT04169997). Citation Format: Sui Xiong Cai, Ning Ma, Xiaozhu Wang, Yangzhen Jiang, Mingchuan Guo, Chih-Yi Hsieh, Ye Edward Tian. Discovery and development of PARP inhibitor senaparib [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1399.
APA, Harvard, Vancouver, ISO, and other styles
3

Xie, Heng Xing. "Analysis of Water Environmental Quality Using BP Artificial Neural Network in Weihe River Baoji Segment." Applied Mechanics and Materials 401-403 (September 2013): 2147–50. http://dx.doi.org/10.4028/www.scientific.net/amm.401-403.2147.

Full text
Abstract:
The BP artificial neural network model in type 7-5-5 was constructed with the surface water quality standard (GB3838-2002) and the surface water quality items such as BOD5 (5 day biochemical oxygen demand), COD (chemical oxygen demand), permanganate index, fluoride, NH3-N, TP (total phosphorus) and TN (total nitrogen), and the water environmental quality evaluation was conducted using the trained BP artificial neural network with the water contamination concentration data in 6 sections of Weihe river Baoji segment in year 2009. Results showed that the water quality were GradeIand GradeII in Lin Jia Cun section and Sheng Li Qiao section, and Grade III in the rest section (Wo Long Si Bridge, Guo Zhen Bridge, Cai Jia Po Bridge and Chang Xing Bridge).
APA, Harvard, Vancouver, ISO, and other styles
4

Liang, jiaqi, Dai Cheng, Yali Guo, xiaobin zhang, Xipan Liu, Jia Fu, Qiang Ding, et al. "Abstract 2568: ARTS-021 is a potent and selective CDK2 inhibitor that demonstrates anti-cancer activity in preclinical cancer models with CCNE1 amplification." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2568. http://dx.doi.org/10.1158/1538-7445.am2022-2568.

Full text
Abstract:
Abstract Cyclin E1 amplification is prevalent in cancers with high unmet medical need such as high grade serous ovarian cancer, stomach cancer and esophageal cancer. Cancer cell lines with high expression level of cyclin E1 gene exhibited profound sensitivity to CDK2 gene depletion, suggesting CDK2 selective inhibitors have the potential to treat patients harboring Cyclin E1 alterations. Here we report the development and preclinical characterization of ARTS-021, an orally bioavailable small molecule CDK2 selective inhibitor. In enzymatic assay against a panel of different CDKs, ARTS-021 potently inhibits the activity of CDK2/CyclinE1 complex with 50% inhibitory concentration (IC50) in the sub-nanomolar range, displaying superior selectivity against other CDKs (CDK1,4,6,7,9). Very low hit rate (S(10)=0.022, at 1uM) is observed when ARTS-021 is assessed in whole Kinome profiling, further revealing the selectivity of this compound. ARTS-021 also demonstrates potent CDK2 inhibition and selectivity against other CDK family members (CDK1,4,6,9) in a series of cellular assays. Consistent with genetic CDK2 dependence data, cell lines with CCNE1 amplification are particularly sensitive to ARTS-021. Double nanomolar ARTS-021 inhibits Rb phosphorylation and blocks G1/S transition, leading to cell growth arrest specifically in CCNE1 amplified cell lines. This CDK2 dependent anti-tumor activity is further validated in vivo, where daily ARTS-021 administration leads to tumor stasis in CCNE1 amplified but not wild type xenograft models. Taken together, these data demonstrate ARTS-021 as a promising CDK2 selective inhibitor with strong potential towards the development of effective therapies for CCNE1 altered cancer. Citation Format: jiaqi Liang, Dai Cheng, Yali Guo, xiaobin zhang, Xipan Liu, Jia Fu, Qiang Ding, Wen Xiong, Fang Li, Yaoyu Chen, Qing Sheng. ARTS-021 is a potent and selective CDK2 inhibitor that demonstrates anti-cancer activity in preclinical cancer models with CCNE1 amplification [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2568.
APA, Harvard, Vancouver, ISO, and other styles
5

Coles, Benjamin. "Guo Xiang and the Problem of Self-Cultivation in Daoist Naturalism." Religions 10, no. 6 (June 18, 2019): 388. http://dx.doi.org/10.3390/rel10060388.

Full text
Abstract:
Recent research on Daoism has distinguished various models of self-cultivation present in the tradition, in particular those which aim at returning humanity to a natural, spontaneous form of existence (often associated with early pre-Qin “philosophical” Daoism), and those which aim at transcending human nature through technical practices (often associated with later “religious” Daoism). During the Wei-Jin period, organized Daoist religion was still in its early stages, yet the difference between the two models was very much an issue in the Dark Learning (xuanxue) thought of the intellectual elite. In this paper, I trace this debate as expressed in Wei-Jin thinker Guo Xiang’s Commentary to the Zhuangzi, in particular in Guo’s criticisms of the desire or attempt to exceed the limits (ji) of one’s inherent nature and his reinterpretation of the Zhuangzi’s criticisms of technical practices. While Guo follows Xiang Xiu in rejecting many of the claims of radical transcendence through self-cultivation, I argue that this does not imply that he lacks any positive conception of self-cultivation, but rather that he sees such cultivation as only possible through an immanent historical process in which both natural spontaneity and artificial techniques have a role to play.
APA, Harvard, Vancouver, ISO, and other styles
6

Liu, Xing, Cunxiang Ju, Hongyan Sun, Jing Zhao, Xiang Gao, and Zhiying Li. "Abstract 1665: Humanized mice for preclinical efficacy evaluation of drugs targeting CD73." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1665. http://dx.doi.org/10.1158/1538-7445.am2022-1665.

Full text
Abstract:
Abstract CD73 expressed in Treg surface facilities the hydrolysis of AMP into adenosine which inhibits the activation, expansion and homing of T effector cells.Therapeutic efficiency of CD73 mAb had been studied in C57BL/6 and BALB/C mice xenografted with several murine cancer cell lines. However, for human CD73 mAb with no binding to murine CD73, CD73 humanized mouse models are essential for medicinal development.We established CD73 humanized mouse model (hCD73) on C57BL/6 and BALB/c background in which the mCD73 was replaced with hCD73. Similar expression level of hCD73 in peripheral blood was observed compared with mCD73 in wildtype mice. Besides, the proportion of T, B and NK cells in spleen of hCD73 mice were also analogy to that in wildtype mice. After treating with anti-hCD73 antibody, tumor growth was inhibited in our CT-26-hCD73 tumor model.Furthermore, hPD1/hPDL1/hCD73 mouse models were also established on C57BL/6 and BALB/c backgrounds based on hCD73 mice. However, a better anti-tumor effect of anti-CD73 antibody was found on BALB/c-hPD1/hPDL1/hCD73 bearing CT26 than that on B6-hPD1/hPDL1/hCD73 bearing MC38. Besides, Combination of anti-CD73 and anti-PD1 significant elevated anti-tumor effect comparing with anti-CD73 and anti-PD1 mono therapy in BALB/c-hPD1/hPDL1/hCD73 mice bearing CT26-hPDL1hCD73.In conclusion, BALB/c-hPD1/hPDL1/hCD73 is a well efficient mouse model for therapeutic effect study of anti-CD73 and relevant combination therapy. Citation Format: Xing Liu, Cunxiang Ju, Hongyan Sun, Jing Zhao, Xiang Gao, Zhiying Li. Humanized mice for preclinical efficacy evaluation of drugs targeting CD73 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1665.
APA, Harvard, Vancouver, ISO, and other styles
7

Zhang, J., X. Guo, Q. Bu, X. Shen, and Z. Feng. "AB0082 ANTI-INFLAMMATORY EFFECTS OF TOTAL SAPONINS OF PANAX JAPONICUS ON RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1173.1–1173. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3460.

Full text
Abstract:
BackgroundRheumatoid arthritis (RA) is a common autoimmune disease with inflammation[1]. Total saponins of Panax japonicus (TSPJs) are effective components extracted from Panax japonicus[2]. They are known to exhibit anti-inflammatory and immunosuppressoive properties, but their effect of anti-inflammation in collagen-induced arthritis (CIA) remains unclear.ObjectivesTo investigate the anti-inflammatory targets of TSPJ predicted by bioinformatics and the verification in CIA mice.MethodsThe targets of RA are obtained in the GeneCards database. we used Cytoscape 3.7.2 software to construct a protein-protein interactions (PPI) network and obtain the hub genes. There are four effective components of TSPJ: Araloside A, chikusetsusaponin IVa, ginsenoside Rg2, and ginsenoside Ro. Through molecular docking between the screened hub genes and the four effective components of TSPJ, the possibility of TSPJ treating CIA mice can be predicted. The collagen II (CII) and complete Freund’s adjuvant (CFA) were used to induce the CIA model. After establishing the model, 32 DBA1/J mice were divided into C group (n=8), M group (n=8), L group(n=8), and H group(n=8). The L and H groups were gavaged with TSPJ at 30 mg/kg or 150 mg/kg, and the C and M groups were gavaged with normal saline. The thickness of the hind paw, number of swollen joints, and arthritis index were evaluated. After 11 days of treatment, all the mice were sacrificed after anesthesia. Sera were collected to centrifuge tubes and the levels of inflammatory factor were determined by the ELISA kit following the instruction.ResultsA gene list that enriches 263 genes was obtained by searching RA from the GeneCards database. The hub genes of the top 3 obtained from Cytoscape 3.7.2 software were tumor necrosis factor (TNF), interleukin-1β (IL-1β), and interleukin-6 (IL-6). In addition, interleukin-17A (IL-17A), a classical inflammatory index in the top 10, was selected and included in the predicted target. The results of molecular docking between the predicted target and the components of TSPJ showed that the combined pose has good stability. The numerical value of hind paw thickness, swollen joint counts, and arthritis index in the intervention groups were lower than those in the M group, suggesting TSPJ played a critical role in improving pathological changes. Compared to those of the C group, the serum levels of TNF-α, IL-1β, IL-6, and IL-17A were increased in the M group. Compared to those of the M group, the levels of TNF-α, IL-1β, IL-6, and IL-17A in the L and H groups were decreased. Compared to those of the L group, the levels of TNF-α, IL-1β, IL-6, and IL-17A in the H group were decreased. The results suggested that TSPJ may decrease the levels of TNF-α, IL-1β, IL-6, and IL-17A in CIA mice. These results suggest that TSPJ may inhibit the inflammatory effects of CIA mice.ConclusionCurrent study demonstrated a novel inhibitory effect of TSPJ on inflammation in CIA mice, and TSPJ can act on the targets predicted by bioinformatics of CIA mice, suggesting the potential of TSPJ as a therapeutic agent for RA and providing new ideas for the clinical treatment of RA.References[1]Scherer HU, Haupl T, Burmester GR. The etiology of rheumatoid arthritis. J Autoimmun[J]. 2020;110:102400[2]Guo X, Ji J, Jose Kumar Sreena GS, et al. Computational Prediction of Antiangiogenesis Synergistic Mechanisms of Total Saponins of Panax japonicus Against Rheumatoid Arthritis. Front Pharmacol[J]. 2020;11:566129AcknowledgementsJingkai Zhang: Preparation, data presentation, and specifically writing the initial draft. Xiang Guo: Application of statistical, Verification. Qinpeng Bu and Xiaolan Shen: Conducting a research and investigation process, Provision of study materials. Zhitao Feng: Ideas, Design of methodology, and including mentorship external to the core team.Disclosure of InterestsNone declared
APA, Harvard, Vancouver, ISO, and other styles
8

Augusto, Pedro E. D., Alberto C. Miano, and Meliza Lindsay Rojas. "Evaluating the Guo-Campanella viscoelastic model." Journal of Texture Studies 49, no. 1 (September 10, 2017): 121–28. http://dx.doi.org/10.1111/jtxs.12297.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Cheng, L., S. X. Zhang, S. Song, C. Zheng, X. Sun, S. Feng, T. Kong, et al. "POS0458 IDENTIFICATION OF HUB GENES AND MOLECULAR PATHWAYS IN PATIENTS WITH RHEUMATOID ARTHRITIS BY BIOINFORMATICS ANALYSIS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 460.1–460. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1938.

Full text
Abstract:
Background:Rheumatoid arthritis (RA) is a chronic, inflammatory synovitis based systemic disease of unknown etiology1. The genes and pathways in the inflamed synovium of RA patients are poorly understood.Objectives:This study aims to identify differentially expressed genes (DEGs) associated with the progression of synovitis in RA using bioinformatics analysis and explore its pathogenesis2.Methods:RA expression profile microarray data GSE89408 were acquired from the public gene chip database (GEO), including 152 synovial tissue samples from RA and 28 healthy synovial tissue samples. The DEGs of RA synovial tissues were screened by adopting the R software. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed. Protein-protein interaction (PPI) networks were assembled with Cytoscape software.Results:A total of 654 DEGs (268 up-regulated genes and 386 down-regulated genes) were obtained by the differential analysis. The GO enrichment results showed that the up-regulated genes were significantly enriched in the biological processes of myeloid leukocyte activation, cellular response to interferon-gamma and immune response-regulating signaling pathway, and the down-regulated genes were significantly enriched in the biological processes of extracellular matrix, retinoid metabolic process and regulation of lipid metabolic process. The KEGG annotation showed the up-regulated genes mainly participated in the staphylococcus aureus infection, chemokine signaling pathway, lysosome signaling pathway and the down-regulated genes mainly participated in the PPAR signaling pathway, AMPK signaling pathway, ECM-receptor interaction and so on. The 9 hub genes (PTPRC, TLR2, tyrobp, CTSS, CCL2, CCR5, B2M, fcgr1a and PPBP) were obtained based on the String database model by using the Cytoscape software and cytoHubba plugin3.Conclusion:The findings identified the molecular mechanisms and the key hub genes of pathogenesis and progression of RA.References:[1]Xiong Y, Mi BB, Liu MF, et al. Bioinformatics Analysis and Identification of Genes and Molecular Pathways Involved in Synovial Inflammation in Rheumatoid Arthritis. Med Sci Monit 2019;25:2246-56. doi: 10.12659/MSM.915451 [published Online First: 2019/03/28][2]Mun S, Lee J, Park A, et al. Proteomics Approach for the Discovery of Rheumatoid Arthritis Biomarkers Using Mass Spectrometry. Int J Mol Sci 2019;20(18) doi: 10.3390/ijms20184368 [published Online First: 2019/09/08][3]Zhu N, Hou J, Wu Y, et al. Identification of key genes in rheumatoid arthritis and osteoarthritis based on bioinformatics analysis. Medicine (Baltimore) 2018;97(22):e10997. doi: 10.1097/MD.0000000000010997 [published Online First: 2018/06/01]Acknowledgements:This project was supported by National Science Foundation of China (82001740), Open Fund from the Key Laboratory of Cellular Physiology (Shanxi Medical University) (KLCP2019) and Innovation Plan for Postgraduate Education in Shanxi Province (2020BY078).Disclosure of Interests:None declared
APA, Harvard, Vancouver, ISO, and other styles
10

Xiong, Wen, Haoyue Ma, Zhu Zhang, Meilan Jin, Jian Wang, Yuwei Xu, and Zili Wang. "Retraction: Icariin enhances intestinal barrier function by inhibiting NF-κB signaling pathways and modulating gut microbiota in a piglet model." RSC Advances 13, no. 4 (2023): 2402. http://dx.doi.org/10.1039/d3ra90005c.

Full text
Abstract:
Retraction of ‘Icariin enhances intestinal barrier function by inhibiting NF-κB signaling pathways and modulating gut microbiota in a piglet model’ by Wen Xiong et al., RSC Adv., 2019, 9, 37947–37956, https://doi.org/10.1039/C9RA07176H.
APA, Harvard, Vancouver, ISO, and other styles
11

Xia, Qi, Chun Xiang Xu, and Yong Yu. "Key Replacement Attack on Two Certificateless Signature Schemes without Random Oracles." Key Engineering Materials 439-440 (June 2010): 1606–11. http://dx.doi.org/10.4028/www.scientific.net/kem.439-440.1606.

Full text
Abstract:
Liu et al. proposed the first certificateless signature scheme without random oracles in 2007. However, Xiong et al. showed that Liu et al.'s scheme is insecure against a malicious-but-passive KGC attack and proposed an improved scheme. In ISA 2009, Yuan et al. also proposed a new certificateless signature scheme without random oracles. Although they claimed that the two schemes are secure in the standard model, this paper shows that both Xiong et al.'s improved scheme and Yuan et al.'s new scheme are vulnerable to key replacement attack, where an adversary, obtaining a signature on a message and replacing the public key of a signer, can forge valid signatures on the same message under the replaced public key. We also give the corresponding modifications of the two schemes to resist key replacement attack.
APA, Harvard, Vancouver, ISO, and other styles
12

Li, Yanan, Zengti Li, and Chuanzheng Li. "A Continuous-Time Version of a Delegated Asset Management Problem." Mathematical Problems in Engineering 2020 (November 30, 2020): 1–8. http://dx.doi.org/10.1155/2020/9097321.

Full text
Abstract:
This paper develops a continuous-time model to study the widely used investment mandates in the institutional asset management industry. In this paper, just like He and Xiong (2013), we suppose that the asset management industry has a two-layered incentive structure, and fund families charging investors fixed management fees while compensating individual fund managers based on fund performance. Different from He and Xiong (2013), we suppose that the fund family aims to select an optimal incentive strategy to maximize its terminal benefits, while the fund manager needs to select the optimal effort level and the optimal investment portfolio to maximize his terminal net discounted compensation in a continuous-time model. By using dynamic programming principle and stochastic differential game theory, the optimal strategies and value functions of both sides are derived. At last, numerical studies are provided to illustrate the effects of all the parameters on the optimal strategies. The result reveals that the optimal incentive mechanism will redistribute both the benefit of the fund families and the cost of the fund managers’ effort.
APA, Harvard, Vancouver, ISO, and other styles
13

Artyushenko, V. M., and D. Y. Vinogradov. "The analysis is geometrically stable orbits of spacecraft remote sensing of the Еarth." Informacionno-technologicheskij vestnik 15, no. 1 (March 30, 2018): 12–22. http://dx.doi.org/10.21499/2409-1650-2018-1-12-22.

Full text
Abstract:
The article reviewed and analyzed the class of geometrically stable orbits (GUO). The conditions of stability in the model of the geopotential, taking into account the zonal harmonics. The sequence of calculation of the state vector of GUO in the osculating value of the argument of the latitude with the famous Ascoli-royski longitude of the ascending node, inclination and semimajor axis. The simulation is obtained the altitude profiles of SEE regarding the all-earth ellipsoid model of the gravitational field of the Earth given 7 and 32 zonal harmonics.
APA, Harvard, Vancouver, ISO, and other styles
14

Hong, Haoyuan, Biswajeet Pradhan, Maher Ibrahim Sameen, Wei Chen, and Chong Xu. "Spatial prediction of rotational landslide using geographically weighted regression, logistic regression, and support vector machine models in Xing Guo area (China)." Geomatics, Natural Hazards and Risk 8, no. 2 (November 25, 2017): 1997–2022. http://dx.doi.org/10.1080/19475705.2017.1403974.

Full text
APA, Harvard, Vancouver, ISO, and other styles
15

Liu, Hong Yan, and Ping Wang. "A Short Remark on WAN Model for Electrospinning and Bubble Electrospinning and Its Development." International Journal of Nonlinear Sciences and Numerical Simulation 16, no. 1 (February 1, 2015): 1–2. http://dx.doi.org/10.1515/ijnsns-2014-0024.

Full text
Abstract:
AbstractThis paper points out that the Bratu-like equation for the charged jet in electrospinning process (Yu-Qin Wan, Qian Guo & Ning Pan, International Journal of Nonlinear Sciences and Numerical Simulation, 5(1), pp. 5–8) requires much improvement.
APA, Harvard, Vancouver, ISO, and other styles
16

Guo, Shijie, Guichang Liu, Qi Zhang, Fang Zhao, and Guomin Ding. "Retraction: Guo, S., et al. Improvement in the Poverty Status of Ecological Migrants under the Urban Resettlement Model: An Empirical Study in China. Sustainability 2020, 12, 2084." Sustainability 12, no. 24 (December 18, 2020): 10595. http://dx.doi.org/10.3390/su122410595.

Full text
APA, Harvard, Vancouver, ISO, and other styles
17

Mishra, Akshaya Kumar, and Ashutosh Kumar. "Modified Guo viscosity model for heavier hydrocarbon components and their mixtures." Journal of Petroleum Science and Engineering 182 (November 2019): 106248. http://dx.doi.org/10.1016/j.petrol.2019.106248.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Chen, Yan, and Yan Zhang. "A NOTE ON TARIFF POLICY, INCREASING RETURNS, AND ENDOGENOUS FLUCTUATIONS." Macroeconomic Dynamics 15, no. 2 (December 14, 2009): 279–91. http://dx.doi.org/10.1017/s1365100509090610.

Full text
Abstract:
We show that the introduction of a constant tariff or subsidy levied on foreign energy can lead to a rich set of endogenous fluctuations around the unique steady state, including stable 2-, 4-, 8-, and 15-cycles, quasiperiodic orbits, and chaos. This is demonstrated in a standard neoclassical growth model with social increasing returns to scale. Numerical exercises could be viewed from a methodological perspective as illustrating that capital income taxes and tariffs are equivalent in generating endogenous fluctuations because Guo and Lansing [Guo, J.T. and K.J. Lansing (2002) Fiscal policy, increasing returns and endogenous fluctuations. Macroeconomic Dynamics 6, 633–664] show that a constant capital tax or subsidy has the same effect on the model dynamics in a one-sector closed economy.
APA, Harvard, Vancouver, ISO, and other styles
19

Wang, Juan, and Yinghui Zhang. "Optimal decay rate for higher–order derivatives of solution to the 3D compressible quantum magnetohydrodynamic model." Advances in Nonlinear Analysis 11, no. 1 (January 1, 2022): 830–49. http://dx.doi.org/10.1515/anona-2021-0219.

Full text
Abstract:
Abstract We investigate optimal decay rates for higher–order spatial derivatives of strong solutions to the 3D Cauchy problem of the compressible viscous quantum magnetohydrodynamic model in the H 5 × H 4 × H 4 framework, and the main novelty of this work is three–fold: First, we show that fourth order spatial derivative of the solution converges to zero at the L 2 - rate ( 1 + t ) - 11 4 {L^2} - {\rm{rate}}\,{(1 + t)^{- {{11} \over 4}}} , which is same as one of the heat equation, and particularly faster than the L 2 - rate ( 1 + t ) - 5 4 {L^2} - {\rm{rate}}\,{(1 + t)^{- {5 \over 4}}} in Pu–Xu [Z. Angew. Math. Phys., 68:1, 2017] and the L 2 - rate ( 1 + t ) - 9 4 {L^2} - {\rm{rate}}\,{(1 + t)^{- {9 \over 4}}} , in Xi–Pu–Guo [Z. Angew. Math. Phys., 70:1, 2019]. Second, we prove that fifth–order spatial derivative of density ρ converges to zero at the L 2 - rate ( 1 + t ) - 13 4 {L^2} - {\rm{rate}}\,{(1 + t)^{- {{13} \over 4}}} , which is same as that of the heat equation, and particularly faster than ones of Pu–Xu [Z. Angew. Math. Phys., 68:1, 2017] and Xi–Pu–Guo [Z. Angew. Math. Phys., 70:1, 2019]. Third, we show that the high-frequency part of the fourth order spatial derivatives of the velocity u and magnetic B converge to zero at the L 2 - rate ( 1 + t ) - 13 4 {L^2} - {\rm{rate}}\,{(1 + t)^{- {{13} \over 4}}} , which are faster than ones of themselves, and totally new as compared to Pu–Xu [Z. Angew. Math. Phys., 68:1, 2017] and Xi–Pu–Guo [Z. Angew. Math. Phys., 70:1, 2019].
APA, Harvard, Vancouver, ISO, and other styles
20

Fu, Shishuo, Jiaxi Lu, and Yuanzhe Ding. "A skeleton model to enumerate standard puzzle sequences." Electronic Research Archive 30, no. 1 (2021): 179–203. http://dx.doi.org/10.3934/era.2022010.

Full text
Abstract:
<abstract><p>Guo-Niu Han [Sémin. Lothar. Comb. 85 (2021) B85c (electronic)] has introduced a new combinatorial object named standard puzzle. We use digraphs to show the relations between numbers in standard puzzles and propose a skeleton model. By this model, we solve the enumeration problem of over fifty thousand standard puzzle sequences. Most of them can be represented by classical numbers, such as Catalan numbers, double factorials, secant numbers and so on. Also, we prove several identities for standard puzzle sequences.</p></abstract>
APA, Harvard, Vancouver, ISO, and other styles
21

Šalamon, Dragica, Alen Džidić, Neven Antunac, Stanko Ivanković, and Vinko Batinić. "Evaluation of lactation models in pasture-based dairy ewes in Bosnia and Herzegovina." Mljekarstvo 70, no. 4 (September 22, 2020): 275–83. http://dx.doi.org/10.15567/mljekarstvo.2020.0405.

Full text
Abstract:
Milk of Kupres, Privor and Stolac dairy ewe breeds is used for the production of the fine cheese varieties. To the best of our knowledge there are no information about milk production and milk composition of these pasture-based dairy ewes. The aim was to determine the best lactation curve model in autochthonous pasture-based dairy ewes in Bosnia and Herzegovina. Milk production was recorded and milk composition sampled (milk fat and protein) during early, mid and late lactation in 129 Kupres, 141 Privor and 129 Stolac pramenka ewes. Four lactation models (Wilmink, Cubic, Ali-Shaeffer and Guo-Swalve) were compared and selected based on the lowest coefficient of determination and root mean square error. The Guo-Swalve model described all of the measured variables most successfully. Kupres pramenka dairy ewe was the highest producing breed with 139 kg of milk during 175 days of lactation (0.79 kg/d; between lactation day 50 to 225) and showed the standard lactation curve. Privor pramenka produced 118 kg of milk during 175 days of lactation (0.67 kg/d) and Stolac pramenka 101 kg of milk during 175 days of lactation (0.58 kg/d). Both showed atypical constantly decreasing shape of the lactation curve common in low producing dairy ewes. The prediction of milk yield and milk composition from the Guo-Swalve model could be used by the national breeding program for the Kupres, Privor and Stolac pramenka sheep breeds. Additional research during a more stable management conditions is recommended for Privor and Stolac pramenka.
APA, Harvard, Vancouver, ISO, and other styles
22

Guo, Y. M., L. B. Guo, Z. Q. Hao, Y. Tang, S. X. Ma, Q. D. Zeng, S. S. Tang, X. Y. Li, Y. F. Lu, and X. Y. Zeng. "Correction: Accuracy improvement of iron ore analysis using laser-induced breakdown spectroscopy with a hybrid sparse partial least squares and least-squares support vector machine model." Journal of Analytical Atomic Spectrometry 35, no. 7 (2020): 1487. http://dx.doi.org/10.1039/d0ja90040k.

Full text
Abstract:
Correction for ‘Accuracy improvement of iron ore analysis using laser-induced breakdown spectroscopy with a hybrid sparse partial least squares and least-squares support vector machine model’ by Y. M. Guo et al., J. Anal. At. Spectrom., 2018, 33, 1330–1335, DOI: 10.1039/C8JA00119G.
APA, Harvard, Vancouver, ISO, and other styles
23

Zhu, Fang, Cunxiang Ju, Hongyan Sun, Weiwei Yu, Chao Ju, Shuai Li, Yunlong Jiang, et al. "Abstract 930: Novel orthotopic pancreatic cancer cell lines derived from B6-KPC mice." Cancer Research 82, no. 12_Supplement (June 15, 2022): 930. http://dx.doi.org/10.1158/1538-7445.am2022-930.

Full text
Abstract:
Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies due to its late diagnosis and limited response to treatment. B6-KPC mice ( LSL-KrasG12D/+, LSL-Trp53R172H/+, Pdx1-Cre) generate spontaneous PDAC which could recapitulate the pathogenesis and genomic features of human PDAC. Although B6-KPC model is a wildly used for the exploration of the mechanisms of PDAC, some drawbacks of the model, such as long time for tumorigenesis, individual variation and difficulties in tumor observation, limit its application in cancer therapy. It is necessary to develop the pancreatic tumor cell lines from these models. In this study, we successfully established and well-characterized the luciferase-labled cell line mPAKPC-Luciferase. This cells carried the KrasG12D and Trp53R172H mutation. The orthotopic mPAKPC-Luciferase tumor model was well established by implanting tumor cell line into pancreas of B6 wild type mice and the tumor growth was traced by in vivo imaging. Moreover, Gemcitabine or combined with CD40 agonist presented significant tumor growth inhibition in B6 bearing mPAKPC-Luciferase orthotopic mouse models. While anti-PD1 or anti-OX40 had no anti-tumor effects in this model accordance with the low T cell infiltration of mPAKPC modle as a “cold” tumor. In addition, the immune profiling of this cell line showed highly expressed of potential therapeutic targets, including Claudin 18.2, CD47, CD73. Thus, mPAKPC-Luciferase cell lines are valuable models for the PDAC preclinical therapies. Citation Format: Fang Zhu, Cunxiang Ju, Hongyan Sun, Weiwei Yu, Chao Ju, Shuai Li, Yunlong Jiang, Dongjing Jia, Steve Smith, Zhiying Li, Jing Zhao, Xiang Gao. Novel orthotopic pancreatic cancer cell lines derived from B6-KPC mice [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 930.
APA, Harvard, Vancouver, ISO, and other styles
24

Gao, Chong Yang, and Wei Ran Lu. "Thermomechanical Response of Commercially Pure Titanium under Large Plastic Deformation at High Strain Rates." Advanced Materials Research 548 (July 2012): 174–78. http://dx.doi.org/10.4028/www.scientific.net/amr.548.174.

Full text
Abstract:
By using a dislocation-based plastic constitutive model for hcp metals developed by us recently, the dynamic thermomechanical response of an important industrial material, commercially pure titanium (CP-Ti), was described at different temperatures and strain rates. The constitutive parameters of the material are determined by an efficient optimization method for a globally optimal solution. The model can well predict the dynamic response of CP-Ti by the comparison with experimental data and the Nemat-Nasser-Guo model.
APA, Harvard, Vancouver, ISO, and other styles
25

Yuan, Xuzheng, Xuechuan Wang, Guohui Zhao, and Sujie Jiang. "Models for assessment of volatile organic compound diffusivities in leather or leather imitates by mercury intrusion porosimetry test." Journal of Engineered Fibers and Fabrics 14 (January 2019): 155892501984322. http://dx.doi.org/10.1177/1558925019843223.

Full text
Abstract:
Recent studies have been conducted on the characteristics of volatile organic compound emissions; most of them are focused on wood-based building materials, scarcely mentioned about leather or leather imitates. The volatile organic compound emissions of these products may cause poor indoor (vehicle cabins included) air quality. This article takes formaldehyde as an example to study its diffusion in leather. The porous structure of leather was characterized by carrying out mercury intrusion porosimetry test. The formaldehyde diffusivities in leather was assessed by Blondeau et al.’s, Ataka et al.’s, and Xiong et al.’s models which represent parallel, equivalent, and series interconnection of pores, respectively, and validated through independent liquid inner tube diffusion film emission experiments. The results demonstrated that the fractal dimension of leather is 2.19, which indicated it is a porous medium with self-similar pore structure. Most of the pores in leather were macro pores with average diameter 16.56 μm which contributed to 95.9% of whole porosity and the meso pore with average diameter 0.60 μm which contributed to 4.1%. As far as the liquid inner tube diffusion film emission experiment shows, the Xiong model agrees much better with the experimental results than the other two. The two kinds of pores were considered to be serially connected. It is useful for predicting volatile organic compounds diffusion coefficient in a short time and can be applied to the design and development of low volatile organic compound emission leather or leather imitates within further research.
APA, Harvard, Vancouver, ISO, and other styles
26

GERSHUN, NATALIA, and SHARON G. HARRISON. "ASSET PRICING IN DYNAMIC STOCHASTIC GENERAL EQUILIBRIUM MODELS WITH INDETERMINACY." Macroeconomic Dynamics 12, no. 1 (October 1, 2007): 50–71. http://dx.doi.org/10.1017/s1365100507060373.

Full text
Abstract:
We explore asset pricing in the context of the one-sector Benhabib-Farmer-Guo (BFG) model with increasing returns to scale in production and compare our results with financial implications of the standard dynamic stochastic general equilibrium (DSGE) model. Our main goal is to determine the effects of local indeterminacy and the presence of sunspot shocks on asset pricing. We find that the BFG model does not adequately represent key stylized facts of U.S. capital markets and does not improve on the asset-pricing results obtained in the standard DSGE model.
APA, Harvard, Vancouver, ISO, and other styles
27

Rezapour, Shahram, Mohammed Said Souid, Zoubida Bouazza, Azhar Hussain, and Sina Etemad. "On the Fractional Variable Order Thermostat Model: Existence Theory on Cones via Piece-Wise Constant Functions." Journal of Function Spaces 2022 (March 24, 2022): 1–11. http://dx.doi.org/10.1155/2022/8053620.

Full text
Abstract:
In the current manuscript, we intend to investigate the existence, uniqueness, and the stability of positive solution in relation to a fractional version of variable order thermostat model equipped with nonlocal boundary values in the Caputo sense. In fact, we will get help from the constant piece-wise functions for transforming our variable order model into an auxiliary standard model of thermostat. By Guo-Krasnoselskii’s fixed point theorem on cones, we derive the required conditions ensuring the existence property for positive solutions. An example is illustrated to examine the validity of the observed results.
APA, Harvard, Vancouver, ISO, and other styles
28

Loomes, Graham. "Quantitative tests of the Perceived Relative Argument Model: Reply to Guo and Regenwetter (2014)." Psychological Review 121, no. 4 (2014): 706–10. http://dx.doi.org/10.1037/a0037841.

Full text
APA, Harvard, Vancouver, ISO, and other styles
29

Andréani, Tony, and Rémy Herrera. "Which Economic Model for China?—Review ofLa Voie chinoiseby Michel Aglietta and Guo Bai." International Critical Thought 5, no. 1 (January 2, 2015): 111–25. http://dx.doi.org/10.1080/21598282.2015.996053.

Full text
APA, Harvard, Vancouver, ISO, and other styles
30

Li, Hang, Yong Hong Liu, Ya Zhou Wang, and Jian Ming Ma. "Numerical Simulation of Flow around Cylinder Using the Lattice Boltzmann Method Based on Guo Boundary Condition." Key Engineering Materials 474-476 (April 2011): 422–27. http://dx.doi.org/10.4028/www.scientific.net/kem.474-476.422.

Full text
Abstract:
In this paper, the lattice Boltzmann Method is applied to simulate incompressible steady flow around a cylinder. The simulation model is based on D2Q9 lattice model and Guo boundary condition. Different Reynolds number and cylinder position in the flow field is considered to acquire corresponding velocity, vorticity, pressure and kinetic energy. The conclusions demonstrated in this paper could be useful for the project like construction of ocean platform, cooling tower or high chimney and so on.
APA, Harvard, Vancouver, ISO, and other styles
31

Yabuuchi, Yoshiyuki, and Junzo Watada. "Japanese Economic Analysis by Possibilistic Regression Model Building Through Possibility Maximization." Journal of Advanced Computational Intelligence and Intelligent Informatics 16, no. 5 (July 20, 2012): 576–80. http://dx.doi.org/10.20965/jaciii.2012.p0576.

Full text
Abstract:
A possibilistic regression model illustrates the potential possibilities inherent in the target system by including all data in the model. Tanaka and Guo employ exponential possibility distribution to build a model, while Inuiguchi et al. and Tajima are independently working on coinciding between the center of a possibility distribution and the center of a possibilistic regression model. Typically, samples influence and distort the shape of the model if they are far from the center of data. Yabuuchi and Watada have developed a model for describing the system possibility using the center of a possibilistic fuzzy regression model and an approach that mends the distortion of the model. The objective of this paper is to analyze the Japanese economy using our model, and to show the usefulness of our model by analysis results.
APA, Harvard, Vancouver, ISO, and other styles
32

Koçak, Ö., and B. Ekiz. "Comparison of different lactation curve models in Holstein cows raised on a farm in the south-eastern Anatolia region." Archives Animal Breeding 51, no. 4 (October 10, 2008): 329–37. http://dx.doi.org/10.5194/aab-51-329-2008.

Full text
Abstract:
Abstract. The objective of this study was to compare the goodness of fit of seven mathematical models (including the gamma function, the exponential model, the mixed log model, the inverse quadratic polynomial model and their various modifications) on daily milk yield records. The criteria used to compare models were mean R2, root mean squared errors (RMSE) and difference between actual and predicted lactation milk yields. The effect of lactation number on curve parameters was significant for models with three parameters. Third lactation cows had the highest intercept post-calving, greatest incline between calving and peak milk yield and greatest decline between peak milk yield and end of lactation. Latest peak production occurred in first lactation for all models, while third lactation cows had the earliest day of peak production. The R2 values ranged between 0.590 and 0.650 for first lactation, between 0.703 and 0.773 for second lactation and between 0.686 and 0.824 for third lactation, depending on the model fitted. The root mean squared error values of different models varied between 1.748 kg and 2.556 kg for first parity cows, between 2.133 kg and 3.284 kg for second parity cows and between 2.342 kg and 7.898 kg for third parity cows. Lactation milk yield deviations of Ali and Schaeffer, Wilmink and Guo and Swalve Models were close to zero for all lactations. Ali and Schaeffer Model had the highest R2 for all lactations and also yielded smallest RMSE and actual and predicted lactation milk yield differences. Wilmink and Guo and Swalve Models gave better fit than other three parameter models.
APA, Harvard, Vancouver, ISO, and other styles
33

Song, Zhiyao, Zhuo Zhang, and Ling Li. "QUANTIFICATION OF TIDAL WATERTABLE OVERHEIGHT DUE TO THE SLOPING BEACH IN UNCONFINED AQUIFERS." Coastal Engineering Proceedings 1, no. 32 (February 1, 2011): 33. http://dx.doi.org/10.9753/icce.v32.currents.33.

Full text
Abstract:
Based on a liberalized one-dimensional Boussinesq model and the previous study results, this paper provides two experience solutions to quantify the tidal groundwater overheight behind arbitrary sloping beaches. One solution is obtained with an asymptotic matching method advanced by Guo, and the other solution is origined by the analytical solution as perturbation parameter less than unity, the errors of both solutions compared with numerical solution are small and acceptive for the application.
APA, Harvard, Vancouver, ISO, and other styles
34

Artiushin, S., J. F. Timoney, J. Nally, and A. Verma. "Host-Inducible Immunogenic Sphingomyelinase-Like Protein, Lk73.5, of Leptospira interrogans." Infection and Immunity 72, no. 2 (February 2004): 742–49. http://dx.doi.org/10.1128/iai.72.2.742-749.2004.

Full text
Abstract:
ABSTRACT Leptospira interrogans causes a variety of clinical syndromes in animals and humans. Although much information has accumulated on the importance of leptospiral lipopolysaccharide in protective antibody responses, relatively little is known about proteins that participate in immune responses. Identification of those proteins induced only in the host is particularly difficult. Using a novel double-antibody screen designed to identify clones in a gene library of L. interrogans serovar Pomona expressing host-inducible proteins, we have characterized a gene (lk75.3) encoding a sphingomyelinase-like preprotein of 648 amino acids with cytotoxic activity for equine pulmonary endothelial cells and weak hemolytic activity for equine and rabbit erythrocytes. lk73.5 was found as a single gene copy in all serovars of L. interrogans but not in other Leptospira spp. except L. inadai. The open reading frame (ORF) for Lk73.5 is followed by another partially homologous sequence containing an ORF (sph-like 2) for a 28.7-kDa peptide. Lk73.5 and Sph-like 2 share 95.1 and 97.7% amino acid identity with putative sphingomyelinases Sph2 and Sph1 (N terminus) from L. interrogans serovar Lai (S.-X. Ren, G. Fu, X.-G. Jiangk, R. Zeng, Y.-G. Miao, H. Xu, Y.-X. Zhang, H. Xiong, G. Lu, L.-F. Lu, H.-Q. Jiang, J. Jia, Y.-F. Tu, J.-X. Jiang, W.-Y. Gu, Y.-Q. Zhang, Z. Cai, H.-H. Sheng, H.-F. Yin, Y. Zhang, G.-F. Zhu, M. Wank, H.-L. Huangk, Z. Qian, S.-Y. Wang, Wei Ma, Z.-J. Yao, Y. Shen, B.-Q. Qiang, Q.-C. Xia, X.-K. Guo, A. Danchinq, I. S. Girons, R. L. Somerville, Y.-M. Wen, M.-H. Shik, Z. Chen, J.-G. Xuk, and G.-P. Zhao, Nature 422:88-893, 2003). Substantial homologies to sphingomyelinases from other leptospiras and other bacteria are also present. Lk73.5 was not detected in leptospiras cultured at 30 or 37°C. The recombinant protein reacted strongly with sera from recently infected mares but not with sera from horses vaccinated with commercial pentavalent bacterin. The host-inducible immunogenic Lk73.5 should have value in distinguishing vaccine from infection immune response.
APA, Harvard, Vancouver, ISO, and other styles
35

Yang, He, Minggao Tang, Qiang Xu, Zhengfeng Gong, Xiaolin Fu, Andres Alonso-Rodriguez, Huajin Li, and Yangjian Cao. "Characteristics and hysteresis of saturated-unsaturated seepage of soil landslides in the Three Gorges Reservoir Area, China." Open Geosciences 11, no. 1 (July 16, 2019): 298–312. http://dx.doi.org/10.1515/geo-2019-0024.

Full text
Abstract:
Abstract The characteristics and hysteresis of seepage are critical for assessing the stability of creeping soil landslides after reservoir impoundment. First, field and laboratory tests were conducted to obtain the saturated permeability coefficient of 396 soil landslides within the Three Gorges Reservoir area and trends among these results were obtained through basic statistics. Second, geological surveys show that these soil landslides are mainly composed of mixed soil-rock structures. Thus, a pressure plate instrument was used for estimating the soil-water characteristic parameters of this unsaturated soil-rock mixture. Finally, the seepage characteristics and hysteresis of the soil landslides was analyzed through numerical simulation based on obtained permeability parameters. The results of this research show that the permeability level of the soil landslides in the Three Gorges Reservoir Area is, in overall terms, good and moderate, and the permeability of the soil landslides has certain spatial distribution characteristics. Also, it was found that the parameters a and m of the unsaturated Fredlund-Xing model became larger with increasing gravel particle size, dry density, and plasticity index of the soil particle; all with decreasing gravel content. Behavior of the n parameter shows an opposite trend. Furthermore, more than 90% of landslides show seepage hysteresis as their hysteresis parameter is less than 35. Finally, it was found that the hysteresis coefficient and slope gradient are the key parameters conditioning the hysteresis of soil landslides.
APA, Harvard, Vancouver, ISO, and other styles
36

Wang, Ling-Ban, Jin-Long Cui, Chang-Yu Sun, Qing-Lan Ma, Shuan-Shi Fan, Xiao-Hui Wang, and Guang-Jin Chen. "Review on the Applications and Modifications of the Chen–Guo Model for Hydrate Formation and Dissociation." Energy & Fuels 35, no. 4 (February 7, 2021): 2936–64. http://dx.doi.org/10.1021/acs.energyfuels.0c03977.

Full text
APA, Harvard, Vancouver, ISO, and other styles
37

Guo, Zhen‐Ren, and James J. Sharp. "Closure to “Numerical Model for Sea Outfall Hydraulics” by Zhen‐Ren Guo and James J. Sharp." Journal of Hydraulic Engineering 123, no. 9 (September 1997): 827. http://dx.doi.org/10.1061/(asce)0733-9429(1997)123:9(827.x).

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Zhang, Liangqi, Zhong Zeng, Haiqiong Xie, Zhouhua Qiu, Liping Yao, Yongxiang Zhang, and Yiyu Lu. "An Alternative Lattice Boltzmann Model for Incompressible Flows and its Stabilization." Communications in Computational Physics 21, no. 2 (February 2017): 443–65. http://dx.doi.org/10.4208/cicp.091014.030515a.

Full text
Abstract:
AbstractIn this paper, an alternative lattice Boltzmann (LB)model for incompressible flows is proposed. By modifying directly the moments of the equilibrium distribution function (EDF), the continuous expression of the EDF in tensor Hermite polynomials is derived using the moment expansion and then discretizedwith the discrete velocity vectors of the D2Q9 lattice. The present model as well as its counterpart, the incompressible LB model proposed by Guo, reproduces the incompressible Navier-Stokes (N-S) equations for both steady and unsteady flows. Besides, an alternative pressure formula, which represents the pressure as the diagonal part of the stress tensor, is adopted in the present model. Furthermore, in order to enhance the stability of the present LB model, an additional relaxation time pertaining to the non-hydrodynamic mode is added to the BGK collision operator. The present LB model is validated by two benchmark tests: the cavity flow with different Reynolds number (Re) and the flow past an impulsively started cylinder at Re=40 and 550.
APA, Harvard, Vancouver, ISO, and other styles
39

Zhang, Yu. "Non-Adiabatic Dynamics Simulation of Plasmon-Mediated Chemistry." ECS Meeting Abstracts MA2022-01, no. 36 (July 7, 2022): 1582. http://dx.doi.org/10.1149/ma2022-01361582mtgabs.

Full text
Abstract:
Localized surface plasmon resonances (LSPRs) have attracted much recent attention for their potential in promoting chemical reactions with light. However, the mechanism of LSPR-induced chemical reactions is still not clear and suffers from many controversies. This presentation will discuss the atomic-scale mechanism of plasmonic hot-carrier mediated chemical reaction exampled by H2 dissociation by employing time-dependent density functional calculations theory and non-adiabatic molecular dynamics. The key observation is that there are nested excited states corresponding to both hot-electron excitation and charge transfer [1]. These nested states cross, facilitating the transitions depicted in the desorption induced by the electronic transitions model and the surface hopping model. I believe this is the first time that such a connection has been made based on a first-principles calculation. Diabatization of these states shows that the charge transfer states are responsible for H2 dissociation, while the hot electron states do not. Previous works only identified the hot electron states, thus were unable to explain the dissociation in a convincing way. Moreover, we also found chemical reaction is tunable if the molecule is placed in the center of the plasmonic dimer [2]. The reaction rate can be either suppressed or enhanced depending on the geometry. [1] Q. Wu, L. Zhou, G. C. Schatz, Y. Zhang*, H. Guo*, J. Am. Chem. Soc. 2020, 142, 13090–13101. [2] Y. Zhang*, T. Nelson, S. Tretiak, H. Guo, G. C. Schatz. ACS Nano, 2018, 12, 8415-8422.
APA, Harvard, Vancouver, ISO, and other styles
40

Li, Peng, Na Zhao, Donghua Zhou, Min Cao, Jingjie Li, and Xinling Shi. "Multivariable Time Series Prediction for the Icing Process on Overhead Power Transmission Line." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/256815.

Full text
Abstract:
The design of monitoring and predictive alarm systems is necessary for successful overhead power transmission line icing. Given the characteristics of complexity, nonlinearity, and fitfulness in the line icing process, a model based on a multivariable time series is presented here to predict the icing load of a transmission line. In this model, the time effects of micrometeorology parameters for the icing process have been analyzed. The phase-space reconstruction theory and machine learning method were then applied to establish the prediction model, which fully utilized the history of multivariable time series data in local monitoring systems to represent the mapping relationship between icing load and micrometeorology factors. Relevant to the characteristic of fitfulness in line icing, the simulations were carried out during the same icing process or different process to test the model’s prediction precision and robustness. According to the simulation results for the Tao-Luo-Xiong Transmission Line, this model demonstrates a good accuracy of prediction in different process, if the prediction length is less than two hours, and would be helpful for power grid departments when deciding to take action in advance to address potential icing disasters.
APA, Harvard, Vancouver, ISO, and other styles
41

Gao, Yue, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G. j. g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, et al. "Abstract LB168: Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study." Cancer Research 82, no. 12_Supplement (June 15, 2022): LB168. http://dx.doi.org/10.1158/1538-7445.am2022-lb168.

Full text
Abstract:
Abstract Background: Morpho-physiological alternations of platelets provided a rationale to harness RNA sequencing of tumor-educated platelets (TEPs) for preoperative diagnosis of cancer. Timely, accurate, and non-invasive detection of ovarian cancer in women with adnexal masses presents a significant clinical challenge. Patients and Methods: This intercontinental, hospital-based, diagnostic study included 761 treatment-naïve inpatients with histologically confirmed adnexal masses and 167 healthy controls from nine medical centers (China, n=3; Netherlands, n=5; Poland, n=1) between September 2016 and May 2019. The main outcomes were the performance of TEPs and their combination with CA125 in two Chinese (VC1 and VC2) and the European (VC3) validation cohorts collectively and independently. Exploratory outcome was the value of TEPs in public pan-cancer platelet transcriptome datasets. Results: The AUCs for TEPs in the combined validation cohort, VC1, VC2, and VC3 were 0.918 (95% CI 0.889-0.948), 0.923 (0.855-0.990), 0.918 (0.872-0.963), and 0.887 (0.813-0.960), respectively. Combination of TEPs and CA125 demonstrated an AUC of 0.922 (0.889-0.955) in the combined validation cohort; 0.955 (0.912-0.997) in VC1; 0.939 (0.901-0.977) in VC2; 0.917 (0.824-1.000) in VC3. For subgroup analysis, TEPs exhibited an AUC of 0.858, 0.859, and 0.920 to detect early-stage, borderline, non-epithelial diseases and 0.899 to discriminate ovarian cancer from endometriosis. Analysis of public datasets suggested that TEPs had potential to detect multiple malignancies (Table 1). Conclusions: TEPs had robustness, compatibility, and universality for preoperative diagnosis of ovarian cancer since it withstood validations in populations of different ethnicities, heterogeneous histological subtypes, early-stage ovarian cancer as well as other malignancies. However, these observations warrant prospective validations in a larger population before clinical utilities. Table 1. Performance for TEPs in public pan-cancer datasets. Disease n Healthy Control AUC, area under the curve (95% CI) Women NSCLC (non-small-cell lung cancer) 126 77 0.758 (0.691-0.825) Breast cancer 38 77 0.817 (0.726-0.909) Colorectal cancer 18 77 0.973 (0.945-1.000) Pancreatic cancer 16 77 0.993 (0.981-1.000) Glioblastoma 10 77 0.923 (0.831-1.000) Men NSCLC 119 82 0.746 (0.677-0.815) Colorectal cancer 25 82 0.933 (0.884-0.982) Pancreatic cancer 22 82 0.993 (0.984-1.000) Glioblastoma 19 82 0.981 (0.959-1.000) All NSCLC 245 159 0.774 (0.728-0.820) Colorectal cancer 40 159 0.978 (0.961-0.996) Breast cancer 38 159 0.821 (0.736-0.906) Pancreatic cancer 35 159 0.987 (0.974-0.999) Glioblastoma 35 159 0.931 (0.890-0.972) Hepatobiliary carcinomas 14 159 0.991 (0.978-1.000) Citation Format: Yue Gao, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G.j.g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, Guang-Yao Cai, Gui-Yan Xie, Shao-Qing Zeng, Yuan Wu, Jian-Hua Chi, Qiong Zhang, Xiao-Fei Jiao, Lin-Li Shi, Wan-Rong Lu, Wei-Guo Lv, Xing-Sheng Yang, Jurgen M.j. Piek, Cornelis D de Kroon, C.a.r. Lok, Anna Supernat, Sylwia Łapińska-Szumczyk, Anna Łojkowska, Anna J. Żaczek, Jacek Jassem, Bakhos A. Tannous, Nik Sol, Edward Post, Myron G. Best, Bei-Hua Kong, Xing Xie, Ding Ma, Thomas Wurdinger, An-Yuan Guo, Qing-Lei Gao. Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB168.
APA, Harvard, Vancouver, ISO, and other styles
42

Yu, Weiwei, Cunxiang Ju, Hongyan Sun, Mingkun Zhang, Honghong Bao, Shuai Li, Chao Ju, Jing Zhao, and Xiang Gao. "Abstract 5620: CD34+humanized huHSC-NCG mice engrafted with hematological malignancies models for preclinical study of anti-human CD19 therapeutic antibodies." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5620. http://dx.doi.org/10.1158/1538-7445.am2022-5620.

Full text
Abstract:
Abstract CD19, has become a vital immune and cellular therapeutic target to treat B-cell malignancies, as anti CD19 antibodies has produced remarkable clinical outcomes. Due to the lack of functional murine T cells, as well as B and NK cells, NCG mice engrafted with CDX or PDX models are well suited for evaluating CAR-T anti-tumor efficacy, but do not meet the needs of evaluating in vivo anti-tumor efficacy of anti-human CD19 bispecific or tri-specific antibodies that require functional human T cells.huHSC-NCG mice were established by the engraftment of CD34+ hematopoietic stem cells (HSC) into irradiated NCG mice. Among multi-lineages of human immune cells, the level of reconstituted human CD3+ T cells gradually increased in huHSC-NCG mice from 10 weeks after engraftment for long-term efficacy evaluation study. Both CD8+ cytotoxic and CD4+ helper T lymophocytes were detected by FACS in blood circulation. In this study, we established mice engrafted with Raji-Luciferase lymphoma and orthotopically engrafted with Nalm6-Luciferase leukemia cells. Both Blinatumomab and tri-specific antibodies displayed a pharmacological effect by reducing the proportion and total counts of B cells in circulation, showed significant tumor growth inhibition and prolonged the survival of xenograft huHSC-NCG mice. Taken together, huHSC-NCG mice is an ideal mouse model for preclinical study of bi-specific or tri-specific T cell engager therapeutic antibodies. Citation Format: Weiwei Yu, Cunxiang Ju, Hongyan Sun, Mingkun Zhang, Honghong Bao, Shuai Li, Chao Ju, Jing Zhao, Xiang Gao. CD34+humanized huHSC-NCG mice engrafted with hematological malignancies models for preclinical study of anti-human CD19 therapeutic antibodies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5620.
APA, Harvard, Vancouver, ISO, and other styles
43

Guo, Yanlin. "Prospects for the teaching of translation majors in the new era." APTIF 9 - Reality vs. Illusion 66, no. 4-5 (October 2, 2020): 867–81. http://dx.doi.org/10.1075/babel.00179.guo.

Full text
Abstract:
Abstract Since entering the new era, the translation model has gradually changed with the widespread application of machine translation technology and the rapid development of a translation industry. The mismatch between the demand of employers and the talents trained by universities has become a major problem facing the translation major nowadays. To this end, we should attach more importance to the readjustment of the existent curriculum; students’ practical ability in translation; grasp of the skill of detecting and correcting machine translation errors; combination of translation and relevant professional knowledge.
APA, Harvard, Vancouver, ISO, and other styles
44

Guo, Deyin, Fan Xing, Jingshu Xiao, and Jiaming liang. "Abstract LB537: CDK4/6 inhibition enhances oncolytic efficacy on refractory glioblastoma by potentiating tumor-selective cell killing and T cell activation." Cancer Research 82, no. 12_Supplement (June 15, 2022): LB537. http://dx.doi.org/10.1158/1538-7445.am2022-lb537.

Full text
Abstract:
Abstract Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain tumor. Although oncolytic virus (OV) therapy has been proposed as a potential approach to treat GBM, the resistance is frequently observed because GBM cells are usually nonpermissive to OV. Here, we describe a dual-step drug screen for identifying chemical enhancers of oncolytic virus in GBM. An inhibitor of the cyclin-dependent kinases 4/6 (CDK4/6) was identified as the top enhancer from 1416 FDA-approved drugs, selectively increasing potency of the two OV strains, including VSVΔ51 and Zika virus. Mechanistically, CDK4/6 inhibition promoted the autophagic degradation of MAVS, resulting in impaired antiviral responses and enhanced tumor-selective replication of VSVΔ51 in vitro and in vivo. CDK4/6 inhibition cooperated with VSVΔ51 to induce severe DNA damage stress, leading to the amplification of oncolysis. In GBM xenograft models, combination treatment of CDK4/6 inhibitor and VSVΔ51 significantly inhibited the tumor growth and prolonged the survival time of tumor-bearing mice. Further investigation revealed that CDK4/6 inhibitor and VSVΔ51 synergistically induced the immunogenic cell death and boosted the anti-tumor immunity. Together, our study features a promising approach of treating aggressive GBM through the combination of CDK4/6 inhibitor with OV. Citation Format: Deyin Guo, Fan Xing, Jingshu Xiao, Jiaming liang. CDK4/6 inhibition enhances oncolytic efficacy on refractory glioblastoma by potentiating tumor-selective cell killing and T cell activation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB537.
APA, Harvard, Vancouver, ISO, and other styles
45

Guo, Jindong, Liwen Xiong, Haibin Yuan, Mengna Hu, Bei Zhang, and Ding Zhang. "Abstract 6121: Correlation of tumor immune microenvironment status and driver genes alterations in Chinese non-small-cell lung cancer patients." Cancer Research 82, no. 12_Supplement (June 15, 2022): 6121. http://dx.doi.org/10.1158/1538-7445.am2022-6121.

Full text
Abstract:
Abstract Background: Patients with different driver genes show a variety of immunotherapy efficacy for non-small-cell lung cancer (NSCLC). In addition to PD-L1, the evaluation of the immune microenvironment contributes to a deeper understanding of the mechanisms of immunotherapy resistance. Methods: Tumor tissues from 2674 NSCLC patients were collected. Genetic alterations were profiled using targeted next-generation sequencing with 733 cancer-related genes panel. Immunohistochemistry was used to evaluate the PD-L1 tumor proportion score, (TPS) expression on the surface of tumor cells. Tumor-infiltrating immune cells of 120 tumor samples were labeled with multiple immunofluorescence staining. Results: Overall, CD8+ T cell infiltration level was negatively associated with both EGFR copy number gain (CNG, p &lt; 0.001) and ERBB2 CNG (p = 0.021). Also, the presence of EGFR or ERBB2 CNG was related with fewer natural killer cell infiltration (EGFR: p &lt; 0.001; ERBB2: p = 0.036) and a lower M1/M2 tumor-associated macrophages ratio compared to wild-type tumors (EGFR: p = 0.051; ERBB2: p = 0.036), suggesting a relatively weaker anti-tumor ability. In addition, we noted that KRAS CNV was negatively related to M2 macrophages (p = 0.027). Patients carrying ALK translocation (p &lt; 0.001), ROS1 translocation (p = 0.006), KRAS mutations (p &lt; 0.001) and MET (p &lt; 0.001) mutations had the elevated PD-L1 TPS expressions, while those harboring EGFR (p &lt; 0.001) and ERBB2 mutations (p = 0.001) had lower PD-L1 expression. Compared to the other EGFR mutations, PD-L1 expression in EGFR CNG tumors was higher, and no significant differences were found between CNG and other types of mutation in patients harboring ERBB2, KRAS, MET alterations. Conclusion: NSCLC patients with EGFR CNG and ERBB2 CNG had fewer invasion of cytotoxic T cells and NK cells and a lower M1/M2 macrophages ratio. EGFR CNG may intensively modify the tumor immune microenvironment, which is a possible mechanism contributing to EGFR-TKI resistance. Citation Format: Jindong Guo, Liwen Xiong, Haibin Yuan, Mengna Hu, Bei Zhang, Ding Zhang. Correlation of tumor immune microenvironment status and driver genes alterations in Chinese non-small-cell lung cancer patients [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 6121.
APA, Harvard, Vancouver, ISO, and other styles
46

Jiang, Chengzhi. "Bilingual representation of distance in visual-verbal sign systems: A case study of Guo Xi’s Early Spring." Semiotica 2018, no. 222 (April 25, 2018): 47–80. http://dx.doi.org/10.1515/sem-2015-0126.

Full text
Abstract:
AbstractThe purely cognitive semantic approach to verbal distance representation has recently been enriched from the perspective of visual perception theory. Focusing on visual pragmatic effects, the present paper will use distance cues as a set of analytical tools and adopt the cognitive-functional model proposed elsewhere to further explore the issue of visual-verbal coherence through Guo Xi’s Early Spring and the bilingual museum catalogue entries attached to it, in physical exhibitions or virtual museums, with a particular view to explaining how a linguistics- or stylistics-based analysis endorses the interpretation of a specific artwork on discursive and cultural levels.
APA, Harvard, Vancouver, ISO, and other styles
47

SCHULZE, ACHIM. "Existence and stability of static shells for the Vlasov–Poisson system with a fixed central point mass." Mathematical Proceedings of the Cambridge Philosophical Society 146, no. 2 (March 2009): 489–511. http://dx.doi.org/10.1017/s0305004108001916.

Full text
Abstract:
AbstractWe consider the Vlasov–Poisson system with spherical symmetry and an exterior potential which is induced by a point mass in the center. This system can be used as a simple model for a newtonian galaxy surrounding a black hole. For this system, we establish a global existence result for classical solutions with shell-like initial data, i.e. the support of the density is bounded away from the point mass singularity. We also prove existence and stability of stationary solutions which describe static shells, where we use a variational approach which was established by Y. Guo and G. Rein.
APA, Harvard, Vancouver, ISO, and other styles
48

GUO, S. J., G. Z. KANG, J. ZHANG, and Q. H. KAN. "EFFECTS OF TANGENT OPERATORS ON PREDICTION ACCURACY OF MESO-MECHANICAL CONSTITUTIVE MODEL OF ELASTO-PLASTIC COMPOSITES." International Journal of Computational Methods 11, no. 04 (August 2014): 1350064. http://dx.doi.org/10.1142/s0219876213500643.

Full text
Abstract:
With a newly developed homogenization cyclic constitutive model of particle reinforced metal matrix composites [Guo et al. (2011)], the effects of tangent operators, i.e., continuum and algorithmic tangent operators [defined by Doghri and Ouaar (2003)] on the accuracy of the developed meso-mechanical constitutive model to predict the monotonic tensile and uniaxial ratchetting deformations of SiC P /6061 Al composites were investigated in this work. The predictions were obtained by the developed model with the choices of different tangent operators and various magnitudes of load increments. Comparison of prediction accuracy and necessary error analysis on the results obtained by different tangent operators were conducted. It is shown that: the stress or strain difference in each load increment and produced by using different tangent operators will accumulate step by step; accurate prediction should be obtained by employing a load increment small enough, especially when the algorithmic tangent operator is used in predicting the uniaxial ratchetting of the composites.
APA, Harvard, Vancouver, ISO, and other styles
49

Guo, Gang, Xiangyu Guo, Yachun Wang, Xu Zhang, Shengli Zhang, Xizhi Li, Lin Liu, et al. "Estimation of genetic parameters of fertility traits in Chinese Holstein cattle." Canadian Journal of Animal Science 94, no. 2 (June 2014): 281–85. http://dx.doi.org/10.4141/cjas2013-113.

Full text
Abstract:
Guo, G., Guo, X., Wang, Y., Zhang, X., Zhang, S., Li, X., Liu, L., Shi, W., Usman, T., Wang, X., Du, L. and Zhang, Q. 2014. Estimation of genetic parameters of fertility traits in Chinese Holstein cattle. Can. J. Anim. Sci. 94: 281–285. The objective of this study was to estimate genetic parameters for fertility traits in Chinese Holstein heifers and cows. Data of 20169 animals with 42106 records over a period of 10 yr (2001–2010) were collected from Sanyuan Lvhe Dairy Cattle Center in Beijing, China. Traits included age at first service (AFS), number of services (NS), days from calving to first service (CTFS), days open (DO), and calving interval (CI). Genetic parameters were estimated with multiple-trait animal model using the DMU software. Heritability estimates for AFS, NS, CTFS, DO and CI were 0.100±0.012, 0.040±0.017, 0.034±0.011, 0.053±0.019 and 0.056±0.014, respectively. Genetic correlations between traits observed ranged from −0.13 to 0.99. Genetic correlations between AFS with NS, CTFS, DO and CI were −0.31, 0.15, −0.13 and −0.15, respectively. Calving interval was strongly correlated with NS, CTFS and DO (0.49–0.99), and DO showed strong correlation with NS and CTFS (0.49 and 0.58, respectively). The genetic correlation between CTFS and NS was negative moderate (−0.25). Results were in range with previous literature estimates and can be used in Chinese Holstein genetic evaluation for fertility traits.
APA, Harvard, Vancouver, ISO, and other styles
50

Wen, Zhu, Bin Jia, Tong Liu, and Jun Lin Tao. "The Numerical Simulation Experiment of Exploded in the Flat Box Sealed Structure." Advanced Materials Research 919-921 (April 2014): 262–66. http://dx.doi.org/10.4028/www.scientific.net/amr.919-921.262.

Full text
Abstract:
Basis on the theory of mechanics of explosion, according to nonlinear finite element method shows that dynamic analysis software ANSYS/ls-dyna , the explosion wave propagation in the flat box sealed structure and the distribution of overpressure on the wall is studied under the action of explosion. Combining the reality of [Guo Zhikun experiment and basic data , ANSYS/ls-dyna is used to establish a standard size 4 studio flat box experimental model, within the model corresponding to the positioning of the drug to 220 units of TNT. Through ANSYS/ls-dyna visualization process study the transmission mechanism of shock wave in a flat trunk, acquisition of some points on the wall of the overpressure peak data caused by explosion, combined with experiments of the proceeds of the actual data values were analyzed.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'Xiong and guo model' for other source types:
Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography