Journal articles on the topic 'XIAP inhibitors'
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Löder, Sandra, Melanie Fakler, Irmela Jeremias, Klaus-Michael Debatin, and Simone Fulda. "XIAP Inhibitors Present a Promising New Strategy to Sensitize Childhood Acute Leukemia Cells for Chemotherapy-Induced Apoptosis." Blood 114, no. 22 (November 20, 2009): 3791. http://dx.doi.org/10.1182/blood.v114.22.3791.3791.
Loeder, Sandra, Thorsten Zenz, Andrea Schnaiter, Daniel Mertens, Dirk Winkler, Hartmut Döhner, Klaus-Michael Debatin, Stephan Stilgenbauer, and Simone Fulda. "A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia." Blood 114, no. 22 (November 20, 2009): 731. http://dx.doi.org/10.1182/blood.v114.22.731.731.
Fakler, Melanie, Sandra Löder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, and Simone Fulda. "Small Molecule XIAP Inhibitors Cooperate with TRAIL to Trigger Apoptosis in Childhood Acute Leukemia Cells and Overcome Bcl-2-Mediated Resistance." Blood 112, no. 11 (November 16, 2008): 857. http://dx.doi.org/10.1182/blood.v112.11.857.857.
Schimmer, Aaron D., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober, et al. "Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples." Blood 104, no. 11 (November 16, 2004): 759. http://dx.doi.org/10.1182/blood.v104.11.759.759.
Schimmer, Aaron D., and Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy." Hematology 2005, no. 1 (January 1, 2005): 215–19. http://dx.doi.org/10.1182/asheducation-2005.1.215.
Schimmer, Aaron D., and Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy." Hematology 2005, no. 1 (January 1, 2005): 215–19. http://dx.doi.org/10.1182/asheducation.v2005.1.215.215.
Fakler, Melanie, Sandra Loeder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, and Simone Fulda. "Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistance." Blood 113, no. 8 (February 19, 2009): 1710–22. http://dx.doi.org/10.1182/blood-2007-09-114314.
Seno, Saki, Minori Kimura, Yuki Yashiro, Ryutaro Kimura, Kanae Adachi, Aoi Terabayashi, Mio Takahashi, et al. "β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells." Medicines 8, no. 6 (June 2, 2021): 26. http://dx.doi.org/10.3390/medicines8060026.
Cillessen, Saskia A. G. M., John C. Reed, Kate Welsh, Clemencia Pinilla, Richard Houghten, Erik Hooijberg, José Deurhof, et al. "Small-molecule XIAP antagonist restores caspase-9–mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells." Blood 111, no. 1 (January 1, 2008): 369–75. http://dx.doi.org/10.1182/blood-2007-04-085480.
Gaponova, Tatyana, Andrey Misurin, Larisa Mendeleeva, Elena Varlamova, Elena Parovichnikova, and Valeryi Savchenko. "Expression of XIAP in Multiple Myeloma Patients." Blood 112, no. 11 (November 16, 2008): 5118. http://dx.doi.org/10.1182/blood.v112.11.5118.5118.
Polykretis, Panagis, Enrico Luchinat, Alessio Bonucci, Andrea Giachetti, Melissa A. Graewert, Dmitri I. Svergun, and Lucia Banci. "Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach." IUCrJ 6, no. 5 (August 23, 2019): 948–57. http://dx.doi.org/10.1107/s205225251901073x.
Ding, Dongshen, Liang Hong, and Chang Shu. "MicroRNA-5100 Modulates Lung Cancer Cell Proliferation and Apoptosis via Inhibiting X-Linked Inhibitor of Apoptosis Protein (XIAP) Expression." Journal of Biomaterials and Tissue Engineering 11, no. 10 (October 1, 2021): 2037–43. http://dx.doi.org/10.1166/jbt.2021.2790.
Farag, Marc, Charline Kieffer, Nicolas Guedeney, Anne Sophie Voisin-Chiret, and Jana Sopkova-de Oliveira Santos. "Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain." Molecules 28, no. 13 (June 30, 2023): 5155. http://dx.doi.org/10.3390/molecules28135155.
Zou, Tongtong, Jaladanki N. Rao, Xin Guo, Lan Liu, Huifang M. Zhang, Eric D. Strauch, Barbara L. Bass, and Jian-Ying Wang. "NF-κB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion." American Journal of Physiology-Cell Physiology 286, no. 5 (May 2004): C1009—C1018. http://dx.doi.org/10.1152/ajpcell.00480.2003.
Carter, Bing Z., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober, et al. "Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells." Blood 105, no. 10 (May 15, 2005): 4043–50. http://dx.doi.org/10.1182/blood-2004-08-3168.
Kater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, John Ostresh, Richard Houghten, John C. Reed, Thomas J. Kipps, and Clemencia Pinilla. "Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis." Blood 104, no. 11 (November 16, 2004): 3474. http://dx.doi.org/10.1182/blood.v104.11.3474.3474.
Leverkus, Martin, Martin R. Sprick, Tina Wachter, Thilo Mengling, Bernd Baumann, Edgar Serfling, Eva-B. Bröcker, Matthias Goebeler, Manfred Neumann, and Henning Walczak. "Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation." Molecular and Cellular Biology 23, no. 3 (February 1, 2003): 777–90. http://dx.doi.org/10.1128/mcb.23.3.777-790.2003.
Park, Cheol-Min, Chaohong Sun, Edward T. Olejniczak, Alan E. Wilson, Robert P. Meadows, Stephen F. Betz, Steven W. Elmore, and Stephen W. Fesik. "Non-peptidic small molecule inhibitors of XIAP." Bioorganic & Medicinal Chemistry Letters 15, no. 3 (February 2005): 771–75. http://dx.doi.org/10.1016/j.bmcl.2004.11.010.
Hatton, Olivia, Stacie Lambert, Sheri Krams, and Olivia Martinez. "Syk survival signals in Epstein-Barr virus + B cell lymphomas (165.27)." Journal of Immunology 186, no. 1_Supplement (April 1, 2011): 165.27. http://dx.doi.org/10.4049/jimmunol.186.supp.165.27.
Prager, Gerald W., Judit Mihaly, Patrick M. Brunner, Yuri Koshelnick, Gunilla Hoyer-Hansen, and Bernd R. Binder. "Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein." Blood 113, no. 6 (February 5, 2009): 1383–90. http://dx.doi.org/10.1182/blood-2008-06-164210.
Haug, Jessica, Vijay G. Ramakrishnan, Teresa Kimlinger, Timothy Halling, Linda Wellik, S. Vincent Rajkumar, and Shaji Kumar. "Significant In Vitro Activity of a Novel Inhibitor of Apoptosis (IAP) Inhibitor LC161 In Multiple Myeloma." Blood 116, no. 21 (November 19, 2010): 2998. http://dx.doi.org/10.1182/blood.v116.21.2998.2998.
Cillessen, Saskia A. G. M., John C. Reed, Clemencia Pinilla, Chris J. L. M. Meijer, Erik Hooijberg, Corine J. Hess, Kitty C. M. Castricum, Pim Kortman, Gert J. Ossenkoppele, and Joost J. Oudejans. "Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large B-Cell Lymphoma Cells." Blood 110, no. 11 (November 16, 2007): 803. http://dx.doi.org/10.1182/blood.v110.11.803.803.
Denault, Jean-Bernard, Brendan P. Eckelman, Hwain Shin, Cristina Pop, and Guy S. Salvesen. "Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9." Biochemical Journal 405, no. 1 (June 13, 2007): 11–19. http://dx.doi.org/10.1042/bj20070288.
Mohapatra, Subhra, Baoky Chu, Xiuhua Zhao, Jianguo Tao, Eduardo Sotomayor, and W. Jack Pledger. "Combined Inhibition of CDK and PI3K/Akt Pathways Induces Apoptosis of Mantle Cell Lymphoma." Blood 110, no. 11 (November 16, 2007): 1384. http://dx.doi.org/10.1182/blood.v110.11.1384.1384.
Ho, Andrew T., Qin H. Li, Hitoshi Okada, Tak W. Mak, and Eldad Zacksenhaus. "XIAP Activity Dictates Apaf-1 Dependency for Caspase 9 Activation." Molecular and Cellular Biology 27, no. 16 (June 11, 2007): 5673–85. http://dx.doi.org/10.1128/mcb.00188-07.
Lucas, H., P. M. Bartold, A. A. S. S. K. Dharmapatni, C. A. Holding, and D. R. Haynes. "Inhibition of Apoptosis in Periodontitis." Journal of Dental Research 89, no. 1 (November 30, 2009): 29–33. http://dx.doi.org/10.1177/0022034509350708.
He, Yanjuan, Joan Cain, Lee Ratner, and Leon Bernal-Mizrachi. "Targeting xIAP Is More Important Than Bcl-Xl in Lymphomas with Constitutive Activation of NF-kB." Blood 108, no. 11 (November 1, 2006): 2390. http://dx.doi.org/10.1182/blood.v108.11.2390.2390.
Seca, Hugo, Liliana Santos, Joana Figueiredo, Raquel T. Lima, Jose E. Guimaraes, Clara Sambade, and M. Helena Vasconcelos. "Targeting XIAP for Chemosensitization Purposes: Different Effect with Different Cytotoxic Drugs." Blood 112, no. 11 (November 16, 2008): 1597. http://dx.doi.org/10.1182/blood.v112.11.1597.1597.
Kater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, Richard Houghten, John Ostresh, Adel Nefzi, John C. Reed, Clemencia Pinilla, and Thomas J. Kipps. "Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis." Blood 106, no. 5 (September 1, 2005): 1742–48. http://dx.doi.org/10.1182/blood-2005-02-0695.
Lethier, Mathilde, Karine Huard, Michael Hons, Adrien Favier, Bernhard Brutscher, Elisabetta Boeri Erba, Derek W. Abbott, Stephen Cusack, and Erika Pellegrini. "Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface." Life Science Alliance 6, no. 11 (September 6, 2023): e202201784. http://dx.doi.org/10.26508/lsa.202201784.
Carter, Bing Z., Tae Kon Kim, Duncan H. Mak, Wei Hu, Clemencia Pinilla, John C. Reed, and Michael Andreeff. "AML Progenitor/Stem Cells Overexpress XIAP and Are Sensitive to the Small Molecular XIAP Inhibitor 1396-11." Blood 108, no. 11 (November 16, 2006): 2586. http://dx.doi.org/10.1182/blood.v108.11.2586.2586.
Carter, Bing Z., Steven M. Kornblau, Twee Tsao, Rui-Yu Wang, Wendy D. Schober, Michele Milella, Hsi-Guang Sung, John C. Reed, and Michael Andreeff. "Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis." Blood 102, no. 12 (December 1, 2003): 4179–86. http://dx.doi.org/10.1182/blood-2003-03-0960.
Runckel, Kyle L., Cory Mavis, Joseph Skitzki, Juan J. Gu, Francisco J. Hernandez-Ilizaliturri, and Myron S. Czuczman. "Targeting the X-Linked Inhibitor of Apoptosis Protein (XIAP) Can Promote Tumor Cell Death, and Increase the Cytotoxic Effects of Chemotherapy Agents in in Vitro and In Vivo Models of Rituximab-Resistant Lymphoma." Blood 126, no. 23 (December 3, 2015): 590. http://dx.doi.org/10.1182/blood.v126.23.590.590.
Rajapakse, Hemaka. "Small Molecule Inhibitors of the XIAP Protein-Protein Interaction." Current Topics in Medicinal Chemistry 7, no. 10 (May 1, 2007): 966–71. http://dx.doi.org/10.2174/156802607780906816.
Abbas, Ruqaia, and Sarit Larisch. "Targeting XIAP for Promoting Cancer Cell Death—The Story of ARTS and SMAC." Cells 9, no. 3 (March 9, 2020): 663. http://dx.doi.org/10.3390/cells9030663.
Khan, Sumera, Kyle Runckel, Cory Mavis, Matthew J. Barth, and Francisco J. Hernandez-Ilizaliturri. "Targeting XIAP Via Degradation of MDM-2 By MX69 in Aggressive Lymphomas." Blood 132, Supplement 1 (November 29, 2018): 5379. http://dx.doi.org/10.1182/blood-2018-99-118480.
Toubai, Tomomi, Corinne Rossi, Katherine Oravecz-Wilson, Cynthia Zajac, Hideaki Fujiwawa, Stuart Brabbs, Julia Wu, Yaping Sun, John M. Magenau, and Pavan R. Reddy. "IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)." Blood 128, no. 22 (December 2, 2016): 810. http://dx.doi.org/10.1182/blood.v128.22.810.810.
RYAN, Ciara A., Henning R. STENNICKE, Victor E. NAVA, Jennifer B. BURCH, J. Marie HARDWICK, and Guy S. SALVESEN. "Inhibitor specificity of recombinant and endogenous caspase-9." Biochemical Journal 366, no. 2 (September 1, 2002): 595–601. http://dx.doi.org/10.1042/bj20020863.
Akbar, Rozmeen, Mati Ur Rehman, Asra Khan, Numair Belgaumi, Iman M. Farooqui, Aafia S. Arain, Azhar Hussain Rajabali, and Kulsoom Ghias. "Abstract 2549: Targeting PI3Kinase AKT pathway and anti-apoptotic protein XIAP in chemotherapy-resistant colorectal cancer cells." Cancer Research 83, no. 7_Supplement (April 4, 2023): 2549. http://dx.doi.org/10.1158/1538-7445.am2023-2549.
Kater, Arnon P., Roman Rieger, Kate Welsh, Adel Nefzi, Richard Houghten, John C. Reed, Clemencia Pinilla, and Thomas J. Kipps. "Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells." Blood 104, no. 11 (November 16, 2004): 3475. http://dx.doi.org/10.1182/blood.v104.11.3475.3475.
Cho, Seung-Ju, Young-Jong Kim, Young-Joon Surh, B. Moon Kim, and Seung-Ki Lee. "Ibulocydine Is a Novel Prodrug Cdk Inhibitor That Effectively Induces Apoptosis in Hepatocellular Carcinoma Cells." Journal of Biological Chemistry 286, no. 22 (April 8, 2011): 19662–71. http://dx.doi.org/10.1074/jbc.m110.209551.
Eyrisch, Susanne, Jose L. Medina-Franco, and Volkhard Helms. "Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors." Journal of Molecular Modeling 18, no. 5 (August 30, 2011): 2031–42. http://dx.doi.org/10.1007/s00894-011-1217-y.
Van Themsche, Céline, Isabelle Mathieu, Sophie Parent, and Eric Asselin. "Transforming Growth Factor-β3 Increases the Invasiveness of Endometrial Carcinoma Cells through Phosphatidylinositol 3-Kinase-dependent Up-regulation of X-linked Inhibitor of Apoptosis and Protein Kinase C-dependent Induction of Matrix Metalloproteinase-9." Journal of Biological Chemistry 282, no. 7 (December 6, 2006): 4794–802. http://dx.doi.org/10.1074/jbc.m608497200.
Gu, Juan J., Samuel J. Thompson, Cory Mavis, Matthew J. Barth, Pallawi Torka, and Francisco J. Hernandez-Ilizaliturri. "Targeting MDM2 and XIAP By Idasanutlin in Diffuse Large B-Cell Lymphoma." Blood 134, Supplement_1 (November 13, 2019): 5301. http://dx.doi.org/10.1182/blood-2019-129009.
Huerta-Yepez, Sara, Mario Vega, Dorina Gui, Jonathan Said, and Benjamin Bonavida. "Analysis of YY1 and XIAP Expression, Proteins That Regulate Resistance, in AIDS-NHL Tissue Arrays." Blood 106, no. 11 (November 16, 2005): 1933. http://dx.doi.org/10.1182/blood.v106.11.1933.1933.
Kawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi, et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation." Blood 94, no. 11 (December 1, 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.
Kawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi, et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation." Blood 94, no. 11 (December 1, 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.423a24_3847_3854.
Kitada, Shinichi, Juan M. Zapata, Michael Andreeff, and John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia." Blood 96, no. 2 (July 15, 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.
Kitada, Shinichi, Juan M. Zapata, Michael Andreeff, and John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia." Blood 96, no. 2 (July 15, 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.014k47_393_397.
Todorovic, Lidija, Gorana Stamenkovic, Biljana Vucetic-Tadic, Kazuo Umezawa, Ana Bozovic, Shunichi Yamashita, and Boban Stanojevic. "Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2." Archives of Biological Sciences, no. 00 (2020): 55. http://dx.doi.org/10.2298/abs201010055t.