Relevant bibliographies by topics / Xestospongia testudinaria

Academic literature on the topic 'Xestospongia testudinaria'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Xestospongia testudinaria"

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Asniar Pascayantri, Adryan Fristiohady,Prahedi Setya Ibrahim. "Review Artikel : Aktivitas Antikanker dari Spons Laut Genus Xestospongia." Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) 4, no. 1 (July 6, 2021): 11. http://dx.doi.org/10.35799/pmj.4.1.2021.34519.

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Abstract The discovery of novel agents in the treatment of cancer is still being conducted, one of them is by developing the marine natural resources as an anti-cancer drug. Sponges like the genus Xestospongia, are natural marine resources that have potential as anti-cancer. Thus,, this review aims to showing the potential of the genus Xestospongia as an anticancer. This review was carried out by collecting the literature from various databases from 2014 to 2019. Results obtained that marin sponge Xestospongia, including Xestospongia testudinaria, Xestospongia exigua, Xestospongia muta and Xestospongiawiedemayeri, were used as anticancer. These compounds such as Quinolizidine, Aragusterol, Araguspic and many more.Keywords— Xestospongia, anticancer, cytotoxicity Abstrak Penemuan obat baru dalam pengobatan kanker masih intensif dilakukan, salah satunya dengan pengembangan sumber daya alam laut sebagai obat anti kanker. Spons seperti genus Xestospongia, merupakan sumber daya alam laut yang memiliki potensi sebagai anti kanker. Oleh karena itu, review ini bertujuan untuk menunjukkan potensispons genus Xestospongia sebagai antikanker. Review ini dilakukan dengan mengumpulkan pustaka dari berbagai database dari tahun 2014 hingga 2019. Hasil yang didapatkan bahwa spesies dari Xestospongia seperti Xestospongia testudinaria, Xestospongia exigua, Xestospongia muta dan Xestospongia wiedemayeri tercatat berpotensi sebagai antikanker. Senyawa-senyawa tersebut seperti Quinolizidine, Aragusterol, Araguspic dan masih banyak lagi.Kata Kunci— Xestospongia, antikanker, sitotoksisitas
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Balansa, Walter, and Frets Rieuwpassa. "BERBEDA TAPI SAMA: PLASTISITAS MORFOLOGI SPONGE XESTOSPONGIA TESTUDINARIA DARI PERAIRAN KABUPATEN SITARO DAN SANGIHE?" Jurnal Ilmiah Tindalung 8, no. 1 (December 21, 2022): 17–23. http://dx.doi.org/10.54484/jit.v8i1.493.

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Plastisitas morfologi sponge telah lama menjadi tantangan berat dalam identifikasi jenis sponge dan mempunyai implikasi penting di bidang konservasi spesies, penemuan bahan bioaktif maupun biomaterial berpotensi medis dari invertebrata laut ini. Peran ekologis, kandungan senyawa bioaktif maupun variasi genetik dari X. testudinaria, sponge ikonik di terumbu karang Sulawesi Utara dan Indo-Pasifik ini, telah seringkali dilaporkan. Tetapi penelitian tentang plastisitas X. testudinaria masih sangat terbatas. Untuk menentukan plastisitias X. testudinaria dari Kabupaten Sitaro dan Sangihe, kami membandingkan karakteristik morfologi (contoh, warna, bentuk pertumbuhan, permukaan tubuh, ukuran dan bentuk spikula). Sejauh ini, tiga morfotipe sponge jenis Xestospongia testudinaria telah ditemukan di Kepulauan Sitaro dan Sangihe; (1) morfotipe digitate di Pulau Mahumu, (2) morfotipe lamellate di perairan Enepahembang dan Bebalang dan (3) morfotipe licin di Ulu Siau. Berbeda dengan studi plastisitas X. testudinaria sebelumnya, penelitian kami tidak menunjukkan adanya dominasi dari salah satu morfotipe ini di wilayah di sekitar pelabuhan laut dan daerah dengan masukan sedimentasi tinggi. Kami juga membahas implikasi dari penelitian ini untuk mendapatkan gambaran lebih baik mengenai distribusi berbagai morfotipe X. testudinaria di perairan Nusa Utara. Morphological plasticity in sponge has become a serious challenge in sponge identification and has an important implication in species conservation. Ecological roles, bioactive compounds, and genetic variation of X. testudinaria, the iconic sponge from the coral reef in North Sulawesi and even Indo-Pacific, have been frequently reported. However, research on the plasticity of X. testudinaria remains limited. To determine the plasticity of this species from Sitaro and Sangihe Islands, we compared the morphological characteristics (e.g. color, growth form, surface, size and the style of spicule). So far, three morphotypes of X. testudinaria have been found in Sitaro and Sangihe Island regencies; digitate, lamellate and smooth surfaces. Different from earlier study on plasticity in X. testudinaria, our research did not show domination of any morphotype in areas near seaport and high sedimentation. We also discussed the implication of this research to get a better understanding of the distribution of X. testudinaria with different morphotypes in Nusa Utara waters.
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Ibraham, Ardyansyah, Rudiyansyah Rudiyansyah, and Andi Hairil Alimuddin. "KARAKTERISASI STRUKTUR LIPID DARI SPONS XESTOSPONGIA TESTUDINARIA." Indonesian Journal of Pure and Applied Chemistry 4, no. 1 (April 30, 2021): 30. http://dx.doi.org/10.26418/indonesian.v4i1.45537.

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The aim of this study is to isolate and characterize the structure of metabolite compounds of the sponge Xestospongia testudinaria, which grows in West Kalimantan. 3000 grams of sponges were analyzed through a preparation and extraction process, which produced a methanol-dissolved extract with a mass of 77.2 grams. The methanol-dissolved extract of was parted using n-hexane and dichloromethane as solvents. Based on the results of phytochemical testing, it can be concluded that the dissolved fraction of dichloromethane contains alkaloids and terpenoids or steroids. The purification process was carried out on 2.4 grams of dichloromethane-dissolved fraction by means of vacuum liquid chromatography, and ten separation fractions were obtained with eluated ethyl acetate : n-hexane as eluent. The separation fractions of FD 3, FD 4, FD 5 and FD 6, which have the same chromatogram characteristics were combined to be purified by means of preparative chromatography. The preparative process was carried out with chloroform : methanol 98:2 eluent, and three chromatogram isolates were produced. The chromatogram isolates with Rf = 0.44 and a mass of 8 milligrams were analyzed by FTIR spectroscopy using pellet KBr and 1H-NMR spectroscopy using CD3OD solvent. Based on the results of data analysis, it is concluded that the predicted content of metabolite compound of the Xestospongia testudinaria sponge sample growing in West Kalimantan waters is propyl-6,7,8-trihydroxy-4-pentadecenoate compound, which is a compound of the fat or lipid ester group with a typical IR absorption peak of the C = O group and C – O at wave numbers 1735.93 – 1766.80 cm-1 and 1111.00 – 1315.45 cm-1 and the containing 11 environments of hydrogen atoms scattered in the 1H-NMR chemical shift from 0.85 ppm to 3.97 ppm.
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Bourguet-Kondracki, M. L., M. T. Rakotoarisoa, M. T. Martin, and M. Guyot. "Bioactive bromopolyacetylenes from the marine sponge Xestospongia testudinaria." Tetrahedron Letters 33, no. 2 (January 1992): 225–26. http://dx.doi.org/10.1016/0040-4039(92)88056-b.

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Magadmi, Rania, Kariman Borouk, Diaa T. A. Youssef, Lamiaa A. Shaala, Aziza R. Alrafiah, Rasheed A. Shaik, and Sameer E. Alharthi. "Neuroprotective Effect of Red Sea Marine Sponge Xestospongia testudinaria Extract Using In Vitro and In Vivo Diabetic Peripheral Neuropathy Models." Pharmaceuticals 15, no. 11 (October 24, 2022): 1309. http://dx.doi.org/10.3390/ph15111309.

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Diabetic peripheral neuropathy (DPN) is a common complication of diabetes. Oxidative stress plays an important role in the pathophysiology of DPN. Red Sea marine sponge Xestospongia testudinaria extract has a promising neuroprotective effect, presumably owing to its antioxidant and anti-inflammatory properties. Thus, this study aimed to investigate the neuroprotective effect of the sponge X. testudinaria extract on in vitro and in vivo models of DPN. Mice dorsal root ganglia (DRG) were cultured with high glucose (HG) media and used as an in vitro model of DPN. Some of the DRGs were pre-treated with 2 mg/mL of X. testudinaria. The X. testudinaria extract significantly improved the HG-induced decreased neuronal viability and the neurite length. It improved the oxidative stress biomarkers in DRG cultures. The DPN model was induced in vivo by an injection of streptozotocin at a dose of 150 mg/kg in mice. After 35 days, 0.75 mg/kg of the X. testudinaria extract improved the hot hyperalgesia and the DRG histology. Although the sponge extract did not reduce hyperglycemia, it ameliorated the oxidative stress markers and pro-inflammatory markers in the DRG. In conclusion, the current study demonstrates the neuroprotective effect of Red Sea sponge X. testudinaria extract against experimentally induced DPN through its antioxidant and anti-inflammatory mechanisms.
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Swantara, Made Dira, Wiwik Susanah Rita, Nyoman Suartha, and Kadek Karang Agustina. "Anticancer activities of toxic isolate of Xestospongia testudinaria sponge." Veterinary World 12, no. 9 (September 2019): 1434–40. http://dx.doi.org/10.14202/vetworld.2019.1434-1440.

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Aim: The purposes of this study were to determine the anticancer activity of Xestospongia testudinaria sponge isolate and identify the responsible compounds. Materials and Methods: The metabolites were extracted using methanol maceration at room temperature. The separation and purification of metabolites were performed using fractionation and column chromatography. The toxicity was examined using the brine shrimp lethality assay, and the toxic isolates were tested for anticancer activity against HeLa cells. Gas chromatography-mass spectrometry analysis was used to identify the compounds in the isolate. Results: When the methanol extract was partitioned with n-hexane, chloroform, and n-butanol, the chloroform fraction was the most toxic, with a concentration that results in 50% lethality (LC50) value of 39.81 ppm. After separation of the chloroform extract, fraction B (FB) was the most toxic, with an LC50 value of 44.67 ppm. The isolate from FB showed anticancer activity with a concentration at which 50% of growth was inhibited (IC50) of 2.273 ppm. In total, 21 compounds were identified in anticancer isolates: Nonanedioic acid; tetradecanoic acid; trans-phytol; 2-pentadecanone- 6,10,14-trimethyl; pentadecanoic acid; 2-hexadecen-1-ol, 3,7,11,15-tetramethyl-; pentadecanoic acid; 2-hexadecen-1-ol, 3,7,11,15-tetramethyl-; 2,3,7-trimethyloctanal; palmitic acid; docosanoic acid, ethyl ester; 1,E-11,Z-13-octadecatriene; chloromethyl 4-chlorododecanoate; 1-tricosene; 9,12-octadecadienoic acid; 4,8,12,16-tetramethylheptadecan-4-olide; 1-docosene; heneicosane; phosphonic acid, dioctadecyl ester; dodecane,4,6-dimethyl-; n-tetratriacontane; 1-iodohexadecane; and n-heneicosane. Conclusion: These findings indicate that the isolate of X. testudinaria can be used as a natural anticancer toward HeLa cell.
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Akiyama, Takuya, Kentaro Takada, Tsutomu Oikawa, Nobuyasu Matsuura, Yuji Ise, Shigeru Okada, and Shigeki Matsunaga. "Stimulators of adipogenesis from the marine sponge Xestospongia testudinaria." Tetrahedron 69, no. 32 (August 2013): 6560–64. http://dx.doi.org/10.1016/j.tet.2013.06.007.

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Liew, Yi Jin, Taewoo Ryu, Manuel Aranda, and Timothy Ravasi. "miRNA Repertoires of Demosponges Stylissa carteri and Xestospongia testudinaria." PLOS ONE 11, no. 2 (February 12, 2016): e0149080. http://dx.doi.org/10.1371/journal.pone.0149080.

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9

Quinn, Ronald J., and David J. Tucker. "Further Acetylenic Acids from the Marine Sponge Xestospongia testudinaria." Journal of Natural Products 54, no. 1 (January 1991): 290–94. http://dx.doi.org/10.1021/np50073a037.

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10

El-Gamal, Ali, Shaza Al-Massarani, Lamiaa Shaala, Abdulrahman Alahdald, Mansour Al-Said, Abdelkader Ashour, Ashok Kumar, Maged Abdel-Kader, Wael Abdel-Mageed, and Diaa Youssef. "Cytotoxic Compounds from the Saudi Red Sea Sponge Xestospongia testudinaria." Marine Drugs 14, no. 5 (April 26, 2016): 82. http://dx.doi.org/10.3390/md14050082.

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Dissertations / Theses on the topic "Xestospongia testudinaria"

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Tucker, David John, and n/a. "An Investigation of the Chemical Constituents of Two Species of Marine Sponge." Griffith University. Division of Science and Technology, 1990. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20050826.155059.

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An investigation of the dichioromethane extract of the sponge, Xestospongia testudinaria indicated that the extract was composed of approximately 40% sterols, 30% saturated fatty acids, 10% mono-unsaturated fatty acids and 20% poly-unsaturated acids. The sterol profile was found to vary between two collections of the sponge. In the first collection the major sterol was the C30 compound, xestosterol (4), which had not previously been reported to occur in this species. In the second collection there was a wider distribution of components with cholesterol (2a) being a major constituent and xestosterol being present in a much lower percentage than in the first collection. The poly-unsaturated acid fraction contained an extremely complex mixture. The novel brominated bisacetylenic C18 (47) and brominated C28 (65) acids were found to be the major components. Another six novel brominated acetylenic acids, which were very unstable, were also identified as well as an ester of 4 with 47. The method developed for the separation of the poly-unsaturated acids from the other classes of metabolites and for the isolation of the pure compounds is discussed and their structural elucidation, largely on the basis of NIMR spectroscopy is described. From the hexane extract of Carteriospongia foliascens, two novel bisalkylated norscalarane derivatives (114 and 116) and a bisalkylated scalarane derivative (130) have been isolated. By use of high field NMR and multipulse NMR techniques a complete assignment of the 111 and 13C NMR spectra of 130 has been achieved on 1.5mg of material. This represents the first report of a complete assignment of the 1J4 NMR spectrum of a scalarane derivative. The C-4 stereochemistry of 130 was determined by use of 1H NMR spectroscopic techniques, which gave results in agreement with the previously used 13C NMR method.
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Tucker, David John. "An Investigation of the Chemical Constituents of Two Species of Marine Sponge." Thesis, Griffith University, 1990. http://hdl.handle.net/10072/367459.

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An investigation of the dichioromethane extract of the sponge, Xestospongia testudinaria indicated that the extract was composed of approximately 40% sterols, 30% saturated fatty acids, 10% mono-unsaturated fatty acids and 20% poly-unsaturated acids. The sterol profile was found to vary between two collections of the sponge. In the first collection the major sterol was the C30 compound, xestosterol (4), which had not previously been reported to occur in this species. In the second collection there was a wider distribution of components with cholesterol (2a) being a major constituent and xestosterol being present in a much lower percentage than in the first collection. The poly-unsaturated acid fraction contained an extremely complex mixture. The novel brominated bisacetylenic C18 (47) and brominated C28 (65) acids were found to be the major components. Another six novel brominated acetylenic acids, which were very unstable, were also identified as well as an ester of 4 with 47. The method developed for the separation of the poly-unsaturated acids from the other classes of metabolites and for the isolation of the pure compounds is discussed and their structural elucidation, largely on the basis of NIMR spectroscopy is described. From the hexane extract of Carteriospongia foliascens, two novel bisalkylated norscalarane derivatives (114 and 116) and a bisalkylated scalarane derivative (130) have been isolated. By use of high field NMR and multipulse NMR techniques a complete assignment of the 111 and 13C NMR spectra of 130 has been achieved on 1.5mg of material. This represents the first report of a complete assignment of the 1J4 NMR spectrum of a scalarane derivative. The C-4 stereochemistry of 130 was determined by use of 1H NMR spectroscopic techniques, which gave results in agreement with the previously used 13C NMR method.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
Division of Science and Technology
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Wooster, Michael. "Carbon Flux Through the Giant Barrel Sponge Xestospongia testudinaria in the Red Sea." Thesis, 2017. http://hdl.handle.net/10754/627888.

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Sponges have important ecological functions on coral reefs because they are regionally abundant, competitively dominant, and process large volumes of seawater. The sponge loop hypothesis proposes that sponges consume dissolved organic carbon (DOC) and then releases the carbon as shed cellular detritus back to the reef benthos. Within this context, we examined the carbon flux mediated by the giant barrel sponge, Xestospongia testudinaria, on reefs in the Red Sea, where sponge abundance is comparatively low relative to coral reefs elsewhere, such as the Caribbean. Seawater samples were collected from the incurrent and excurrent (In-Ex) flow of 40 sponges from inshore, mid-shelf, and offshore reefs between 18° and 22°N latitude off the coast of Saudi Arabia. Concentrations of DOC and living particulate organic carbon (LPOC) were significantly higher in incurrent (ambient) seawater on inshore reefs than mid-shelf and offshore reefs. Consistent with studies of X. muta in the Caribbean, the diet of X. testudinaria is comprised primarily of DOC; mean values of the nutritional components across all sites were 60.5% DOC, 35.7% detritus, and 3.8% LPOC. Taking into account the specific filtration rates of nutritional components and oxygen consumption of sponges across the inshore-offshore gradient, there is evidence (1) of a threshold concentration of DOC below which sponges cease to be net consumers of DOC, and (2) that sponges on offshore reefs are food-limited. Contrary to the sponge loop hypothesis, there was no evidence that X. testudinaria, returned DOC to the benthos in the form of detritus, but was, instead, a net consumer of detritus from the water column. Unlike the cryptic, interstitial sponges that were studied to advance the sponge-loop hypothesis, emergent sponges may have an alternate pathway for returning DOC to the benthos by converting it to sponge biomass rather than sponge detritus.
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Conference papers on the topic "Xestospongia testudinaria"

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Subagio, Iwenda Bella, Edwin Setiawan, Sucipto Hariyanto, and Bambang Irawan. "Spicule size variation in Xestospongia testudinaria Lamarck, 1815 at Probolinggo-Situbondo coastal." In PROCEEDING OF INTERNATIONAL BIOLOGY CONFERENCE 2016: Biodiversity and Biotechnology for Human Welfare. Author(s), 2017. http://dx.doi.org/10.1063/1.4985425.

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