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Journal articles on the topic 'Wound care device'

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Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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1

Sloan, Brian K., Haroon Mohammad, Nader S. Abutaleb, and Mohamed N. Seleem. "Comparison between a novel tap water wound irrigation device with sterile saline device in an open traumatic wound animal model." Trauma 22, no. 3 (June 25, 2019): 176–81. http://dx.doi.org/10.1177/1460408619857399.

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Study objective Open traumatic wounds present to US emergency departments at a rate of approximately 12 million per year. Tap water wound irrigation usage has not been adopted by providers thus negating a potential cost saving of approximately US$65,600,000 per year when compared to saline irrigation. A novel tap water wound irrigation device can reduce bacterial counts in rats inoculated with MRSA as effectively as a commonly used sterile saline wound irrigation system. Methods Two groups of six Sprague–Dawley rats were used for this study. Two 3 cm incisions were made into the dorsum of each Sprague–Dawley rat and each incision was inoculated with 100 µl of MRSA. One wound served as the control, the other wound was either irrigated with the sterile saline wound irrigation system or a novel tap water wound irrigation device. The wounds were homogenized, plated, and bacterial colonies were enumerated to determine the final concentration of bacteria in each wound. Results There was no significant statistical difference in the reduction of MRSA in wounds treated with the sterile saline system relative to wounds treated with tap water (one-way ANOVA with post hoc Dunnet's test). Conclusion The novel tap water wound irrigation device is as effective as the sterile saline wound irrigation device at reducing bacterial counts in a rat laceration model when compared to non-irrigated controls. Adopting the use of a convenient, effective, and inexpensive wound irrigation system using tap water could help save the health care system millions of dollars in direct costs, shipping cost, and would not be affected by saline shortages.
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2

O'Callaghan, Suzanne, Paul Galvin, Conor O'Mahony, Zena Moore, and Rosemarie Derwin. "‘Smart’ wound dressings for advanced wound care: a review." Journal of Wound Care 29, no. 7 (July 2, 2020): 394–406. http://dx.doi.org/10.12968/jowc.2020.29.7.394.

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Hard-to-heal wounds are a common side-effect of diabetes, obesity, pressure ulcers and age-related vascular diseases, the incidences of which are growing worldwide. The increasing financial burden of hard-to-heal wounds on global health services has provoked technological research into improving wound diagnostics and therapeutics via ’smart’ dressings, within which elements such as microelectronic sensors, microprocessors and wireless communication radios are embedded. This review highlights the progress being made by research groups worldwide in producing ‘smart’ wound device prototypes. Significant advances have been made, for example, flexible substrates have replaced rigid circuit boards, sensors have been printed on commercial wound dressing materials and wireless communication has been demonstrated. Challenges remain, however, in the areas of power supply, disposability, low-profile components, multiparametric sensing and seamless device integration in commercial wound dressings.
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Wong, Victor W., Bill Beasley, John Zepeda, Reinhold H. Dauskardt, Paul G. Yock, Michael T. Longaker, and Geoffrey C. Gurtner. "A Mechanomodulatory Device to Minimize Incisional Scar Formation." Advances in Wound Care 2, no. 4 (May 2013): 185–94. http://dx.doi.org/10.1089/wound.2012.0396.

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4

Townsend, Katy L., Jen Akeroyd, Duncan S. Russell, Jamie J. Kruzic, Bria L. Robertson, and William Lear. "Comparing the Tolerability of a Novel Wound Closure Device Using a Porcine Wound Model." Advances in Wound Care 7, no. 6 (June 2018): 177–84. http://dx.doi.org/10.1089/wound.2017.0777.

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5

Vu, Hong, Ashwin Nair, Lan Tran, Suvra Pal, Jon Senkowsky, Wenjing Hu, and Liping Tang. "A Device to Predict Short-Term Healing Outcome of Chronic Wounds." Advances in Wound Care 9, no. 6 (June 1, 2020): 312–24. http://dx.doi.org/10.1089/wound.2019.1064.

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6

Choo, Bryan Peide, Jeremy Ting En Low, Hong Choon Oh, Ling Ong, Jocelyn Kaibin Loh, and Gek Kheng Png. "Evaluation of a Mobile Wound Care Device for Assessment of Wounds: A Time Motion Study." Journal of Wound Management and Research 18, no. 3 (October 31, 2022): 170–77. http://dx.doi.org/10.22467/jwmr.2022.01991.

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Background: Comprehensive wound assessments are critical in identifying potential complications that affect wound healing and determining appropriate interventions for the patient. A wound care device (WCD) comprising a mobile device integrated with multi-spectral sensors that can capture stereoscopic and thermal images was recently introduced. A trial was conducted to assess potential productivity gains of the device.Methods: A total of 30 inpatients who required wound care were recruited and assessed via a time motion study. For every patient recruited in this study, wound measurements and documentation steps were repeated twice for a total of 55 wounds, once using the WCD and the other using a conventional manual process, with the order of assessment determined using a random group assignment generator. A t-test was used for statistical analysis.Results: The use of the WCD had a mean process time 4.86 minutes shorter than the conventional manual process (P<0.001). This constituted an increase in productivity by 44% for wound measurement, photography, and documentation. With estimated time savings of 5 minutes per patient, this amounts to 6,631 hours per year or a total of 3.42 nursing full-time equivalent savings per year based on an estimated load of 218 patients per day requiring wound care at an acute care institution in Singapore.Conclusion: The adoption of a mobile WCD has potential to improve work productivity and result in full-time equivalent savings for wound care nurses. Most importantly, the WCD could provide clinically beneficial outcomes for the patient by enhancing the management and documentation of wound care.
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7

Klein, Robert. "Managing Wound Dehiscence With Mechanical Negative Pressure Wound Therapy: A Case Report." Wounds : a compendium of clinical research and practice 34, no. 1 (January 10, 2021): E75—E78. http://dx.doi.org/10.25270/wnds/2021.e7578.

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Mechanical negative pressure wound therapy (mNPWT) is commonly used in the management of a variety of wounds, including diabetic foot ulcerations, surgical wounds, venous ulcerations, and wound dehiscence. This mechanically powered, disposable modality can be used to manage wounds in the outpatient setting and has been shown to be an effective wound care option when transitioning patients from the inpatient to outpatient setting and continuing NPWT for wound care. Mechanical NPWT helps promote wound healing by decreasing edema and via removal of tissue debris and exudate. Traditional NPWT is bulky, is often noisy, and requires a power source. A mechanically powered, disposable, easily applied, off-the-shelf mNPWT device is available for patients with small- to medium-sized wounds with mild to moderate exudate. The disposable mNPWT device provides −125 mm Hg pressure, is silent and small, can be worn under clothes, and allows the patient to be fully ambulatory, thus, more mobile. The mNPWT device tubing can be cut to fit to enable safer ambulation than the powered system and to enable the patient to work and enjoy social activities without a medical device showing. This single case study of a patient with chronic diabetic foot ulcerations of the medial first metatarsal head and dorsal proximal interphalangeal joints of the second and third toes of the left foot, which had not been successfully treated with conservative care and had been present for more than 1 year.
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8

Pena, Guilherme, Beatrice Kuang, Zygmunt Szpak, Prue Cowled, Joseph Dawson, and Robert Fitridge. "Evaluation of a Novel Three-Dimensional Wound Measurement Device for Assessment of Diabetic Foot Ulcers." Advances in Wound Care 9, no. 11 (November 1, 2020): 623–31. http://dx.doi.org/10.1089/wound.2019.0965.

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9

MacKay, Brendan J., Anthony N. Dardano, Andrew M. Klapper, Selene G. Parekh, Mohsin Q. Soliman, and Ian L. Valerio. "Multidisciplinary Application of an External Tissue Expander Device to Improve Patient Outcomes: A Critical Review." Advances in Wound Care 9, no. 9 (September 1, 2020): 525–38. http://dx.doi.org/10.1089/wound.2019.1112.

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10

Hoyo, Javier, Arnau Bassegoda, Guillem Ferreres, Dolores Hinojosa-Caballero, Manuel Gutiérrez-Capitán, Antoni Baldi, César Fernández-Sánchez, and Tzanko Tzanov. "Rapid Colorimetric Detection of Wound Infection with a Fluidic Paper Device." International Journal of Molecular Sciences 23, no. 16 (August 15, 2022): 9129. http://dx.doi.org/10.3390/ijms23169129.

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Current procedures for the assessment of chronic wound infection are time-consuming and require complex instruments and trained personnel. The incidence of chronic wounds worldwide, and the associated economic burden, urge for simple and cheap point-of-care testing (PoCT) devices for fast on-site diagnosis to enable appropriate early treatment. The enzyme myeloperoxidase (MPO), whose activity in infected wounds is about ten times higher than in non-infected wounds, appears to be a suitable biomarker for wound infection diagnosis. Herein, we develop a single-component foldable paper-based device for the detection of MPO in wound fluids. The analyte detection is achieved in two steps: (i) selective immunocapture of MPO, and (ii) reaction of a specific dye with the captured MPO, yielding a purple color with increasing intensity as a function of the MPO activity in infected wounds in the range of 20–85 U/mL. Ex vivo experiments with wound fluids validated the analytic efficiency of the paper-based device, and the results strongly correlate with a spectrophotometric assay.
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11

Buchanan, Krysti, Neil Bernstein, Elizabeth A. Ayello, and Daniel K. O'Neill. "Cardiac Device Interrogation for Safer Care of Surgical Wound Patients." Advances in Skin & Wound Care 24, no. 11 (November 2011): 507–14. http://dx.doi.org/10.1097/01.asw.0000407649.97584.9c.

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12

Minteer, Danielle M., Patsy Simon, Donald P. Taylor, Wenyan Jia, Yuecheng Li, Mingui Sun, and J. Peter Rubin. "Pressure Ulcer Monitoring Platform—A Prospective, Human Subject Clinical Study to Validate Patient Repositioning Monitoring Device to Prevent Pressure Ulcers." Advances in Wound Care 9, no. 1 (January 1, 2020): 28–33. http://dx.doi.org/10.1089/wound.2018.0934.

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13

Nuutila, Kristo, Josh Grolman, Lu Yang, Michael Broomhead, Stuart Lipsitz, Andrew Onderdonk, David Mooney, and Elof Eriksson. "Immediate Treatment of Burn Wounds with High Concentrations of Topical Antibiotics in an Alginate Hydrogel Using a Platform Wound Device." Advances in Wound Care 9, no. 2 (February 1, 2020): 48–60. http://dx.doi.org/10.1089/wound.2019.1018.

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14

Hurley, Ciaran M., Pat McClusky, Ryan M. Sugrue, James A. Clover, and Jason E. Kelly. "Efficacy of a bacterial fluorescence imaging device in an outpatient wound care clinic: a pilot study." Journal of Wound Care 28, no. 7 (July 2, 2019): 438–43. http://dx.doi.org/10.12968/jowc.2019.28.7.438.

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Objective: Subsurface bacterial burden can be missed during standard wound examination protocols. The real-time bacterial fluorescence imaging device, MolecuLight i:X, visualises the presence of potentially harmful levels of bacteria through endogenous autofluorescence, without the need for contrast agents or contact with the patient. The intended use of the imaging device is to assist with the management of patients with wounds by enabling real-time visualisation of potentially harmful bacteria. The aim of this study was to establish the accuracy of the wound imaging device at detecting pathogenic bacteria in wounds. Methods: A single-centre, prospective observational study was conducted in Cork University Hospital in an outpatient plastic surgery wound care clinic. Patients had their wounds photographed under white and autofluorescent light with the imaging device. Auto-fluorescent images were compared with the microbiological swab results. Results: A total of 33 patients and 43 swabs were included, of which 95.3% (n=41) were positive for bacteria growth. Staphylococcus aureus was the most common bacterial species identified. The imaging device had a sensitivity of 100% and specificity of 78% at identifying pathological bacteria presence in wounds on fluorescent light imaging. The positive predictive value (PPV) was 95.4%. The negative predictive value (NPV) was 100%. It demonstrated a sensitivity and specificity of 100% at detecting the presence of Pseudomonas spp. Conclusion: The imaging device used could be a safe, effective, accurate and easy-to-use autofluorescent device to improve the assessment of wounds in the outpatient clinic setting. In conjunction with best clinical practice, the device can be used to guide clinicians use of antibiotics and specialised dressings.
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15

Phillips, Tania J., and Hee-Young Park. "Warm-up™ wound care device reduces the growth inhibitory activity in chronic wound fluid." Journal of Dermatological Science 16 (March 1998): S63. http://dx.doi.org/10.1016/s0923-1811(98)83372-0.

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16

Landsman, Adam. "Analysis of the SNaP™ Wound Care System, a Negative Pressure Wound Device for Treatment of Diabetic Lower Extremity Wounds." Journal of Diabetes Science and Technology 4, no. 4 (July 2010): 831–32. http://dx.doi.org/10.1177/193229681000400410.

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17

Kim, J. Y., D. M. Dunham, D. M. Supp, C. K. Sen, and H. M. Powell. "Novel burn device for rapid, reproducible burn wound generation." Burns 42, no. 2 (March 2016): 384–91. http://dx.doi.org/10.1016/j.burns.2015.08.027.

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18

Evans, Martin, Stephen Kralovic, Gary Roselle, Karen Lipscomb, and Linda Flarida. "Potential Impact of CDC’s Enhanced Barrier Precautions Recommendations on Veterans’ Affairs Long-Term Care Facilities." Infection Control & Hospital Epidemiology 41, S1 (October 2020): s19—s20. http://dx.doi.org/10.1017/ice.2020.494.

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Background: We previously showed that ~25% of Veterans’ Affairs (VA) long-term care facility (LTCF) residents had 1 or more indwelling medical devices. Of these devices, 36% were indwelling urinary catheters, 18% were percutaneous gastrostomy tubes, 12% were peripherally inserted central catheters, 8% were suprapubic urinary catheters, and 6% were peripheral intravenous catheters. Approximately 11% of those with an indwelling device developed an LTCF-acquired infection, compared to 3.5% of those without a device. Methicillin-resistant Staphylococcus aureus (MRSA) is a targeted multidrug-resistant organism (MDRO) in all VA LTCFs nationwide. All admissions to VA LTCFs are screened for MRSA carriage upon admission and, since 2013, those that screen positive (~21%) are placed in VA enhanced barrier precautions (EBPs). VA EBPs require that all healthcare workers entering a resident’s bedroom don gowns and gloves for specific activities likely to be associated with contamination of the worker’s hands and clothes. With proper hand hygiene and clean clothing, the colonized resident is encouraged to leave their bedroom and participate fully in all LTCF activities. In July 2019, the US Centers for Disease Control and Prevention (CDC) recommended the use of EBPs for all residents in LTCFs with a wound or device regardless of their colonization status if a resident is identified within the facility with novel or targeted MDROs including panresistant organisms, carbapenemase-producing gram-negative bacteria, and Candida auris. Methods: We assessed the potential impact of this recommendation on VA LTCFs by asking our 133 LTCFs to do a 1-day point-prevalence survey. Results: In total, 63 sites (47%) responded. On the survey day, there were 4,777 residents in the participating facilities, of whom 891 (18.7%) were under EBPs or contact precautions (CPs) for MRSA or other MDROs. Moreover, 963 (20.2%) residents (not already in EBP or CP) had a wound or an indwelling device such as central venous catheter, urinary catheter, feeding tube, tracheostomy or were on a ventilator (if >1 device, resident counted only once). If newly published CDC recommendations were implemented for novel or targeted MDRO precautions in VA LTCFs nationwide, 1,854 residents (38.8%) in VA LTCFs would be placed under EBPs or CPs. Conclusions: In VA LTCFs, adopting the CDC recommendation to place all patients with wounds or indwelling devices under EBPs regardless of colonization status would increase the percentage of residents on transmission-based precautions to ~40% (nearly doubling those in an isolation precaution status).Funding: NoneDisclosures: None
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19

Diekmann, Judy M., Jane M. Smith, and Joan R. Wilk. "Wound Care Forum: A Double Life for a Dental Irrigation Device." American Journal of Nursing 85, no. 10 (October 1985): 1157. http://dx.doi.org/10.2307/3425214.

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20

Raizman, Rose, Danielle Dunham, Liis Lindvere-Teene, Laura M. Jones, Kim Tapang, Ron Linden, and Monique Y. Rennie. "Use of a bacterial fluorescence imaging device: wound measurement, bacterial detection and targeted debridement." Journal of Wound Care 28, no. 12 (December 2, 2019): 824–34. http://dx.doi.org/10.12968/jowc.2019.28.12.824.

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Objective: Diagnostics which provide objective information to facilitate evidence-based treatment decisions could improve the chance of wound healing. Accurate wound measurements, objective bacterial assessment, and the regular, consistent tracking of these parameters are important aspects of wound care. This study aimed to assess the accuracy, clinical incorporation and documentation capabilities of a handheld bacterial fluorescence imaging device (MolecuLight i:X). Method: Benchtop wound models with known dimensions and clinical wound images were repeatedly measured by trained clinicians to quantify accuracy and intra/inter-user coefficients of variation (COV) of the imaging device measurement software. In a clinical trial of 50 wounds, wound dimensions were digitally measured and fluorescence images were acquired to assess for the presence of bacteria at moderate-to-heavy loads. Finally, fluorescence imaging was implemented into the routine assessment of 22 routine diabetic foot ulcers (DFU) to determine appropriate debridement level and location based on bacterial fluorescence signals. Results: Wound measurement accuracy was >95% (COV <3%). In the clinical trial of 50 wounds, 72% of study wounds demonstrated positive bacterial fluorescence signals. Levine sampling of wounds was found to under-report bacterial loads relative to fluorescence-guided curettage samples. Furthermore, fluorescence documentation of bacterial presence and location(s) resulted in more aggressive, fluorescence-targeted debridement in 17/20 DFUs after standard of care debridement failed to eliminate bacterial fluorescence in 100% of DFU debridements. Conclusion: The bacterial fluorescence imaging device can be readily implemented for objective, evidenced-based wound assessment and documentation at the bedside. Bedside localisation of regions with moderate-to-heavy bacterial loads facilitated improved sampling, debridement targeting and improved wound bed preparation.
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21

Bass, Ellen J., Justine S. Sefcik, Elease McLaurin, and Rose Ann DiMaria-Ghalili. "Considerations for Translating Medical Devices Under Development From the Clinic to the Home: A Case Study in Providing Chronic Wound Care." Proceedings of the International Symposium on Human Factors and Ergonomics in Health Care 10, no. 1 (June 2021): 238–42. http://dx.doi.org/10.1177/2327857921101173.

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A prototype medical device and protocol that work well in a clinic would not necessarily work reliably in the home setting. The goal of this work is to identify factors to consider when translating a device evaluated in a clinic for use by home caregivers providing chronic wound care for persons living with dementia. One must consider the current device, the associated bundle, the protocol and how they may need to be modified. Semi-structured interviews with the research assistants who have applied a prototype device were conducted to generate a list of known issues with the current clinical protocol in terms of ultrasound application The researchers performed a set of specified tasks by following the current device protocol and explaining any difficulties with use\execution. They embellished the descriptions with details about what had happened with actual patients in the clinic. Using thematic analysis, analysts identified themes and subthemes. Issues potentially relevant to translating medical devices to the home are discussed.
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Whitcomb, Emily, Nina Monroe, Jennifer Hope-Higman, and Penny Campbell. "Demonstration of a Microcurrent-Generating Wound Care Device for Wound Healing Within a Rehabilitation Center Patient Population." Journal of the American College of Clinical Wound Specialists 4, no. 2 (June 2012): 32–39. http://dx.doi.org/10.1016/j.jccw.2013.07.001.

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23

Al-Jalodi, Omar, Laura M. Serena, Kristy Breisinger, Keyur Patel, Khristina Harrell, and Thomas E. Serena. "A novel debridement device for the treatment of hard-to-heal wounds: a prospective trial." Journal of Wound Care 30, Sup5 (May 1, 2021): S32—S36. http://dx.doi.org/10.12968/jowc.2021.30.sup5.s32.

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Objective: Debridement, the removal of nonviable tissue, forms the foundation of wound care practice. Clinicians have a variety of debridement methods at their disposal: sharp, biologic, enzymatic, autolytic and mechanical. The choice of debridement technique depends on the patient care setting, ulcer type and the clinician's experience, training, comfort level and licensure. This prospective study evaluated a novel debridement instrument, EZ-Debride (MDM Ventures, US). Cutting flutes on the head of the tool permit uniform removal of dead tissue while lessening the risk of deeper injury. It may also minimise pain during the debridement procedure. Method: Subjects with hard-to-heal wounds, drawn from a single wound care centre, participated in this institutional review board-approved prospective clinical study. Pain was measured before, during and after debridement using a numerical scale. Assessment of bacterial burden using fluorescence imaging (MolecuLight, Canada) was performed before and after debridement. Results: Enrolment of 10 male and 12 female subjects, with a total of 28 wounds, was carried out over a two-month period by two investigators at a single institution. The average age of subjects was 64 years (range: 22–95 years). The average wound duration was 29 weeks (range: 6–142 weeks). Wound types included diabetic foot, venous leg and pressure ulcers, post-surgical and traumatic wounds. The average pain score at the time of enrolment was 3.9. Subjects reported an average increase in pain with debridement of 0.6 points (range: 0–8). Fluorescence imaging demonstrated a reduction in bacterial load in 69% of cases, with complete resolution in 19% of wounds. Haemostasis was achieved with direct pressure in all cases and the only adverse event was a wound infection that occurred four days after debridement. Conclusion: The results suggest that this novel debridement tool can safely remove nonviable tissue with minimal discomfort and reduce bacterial burden similar to results achieved by sharp debridement.
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Vaienti, L., A. Marchesi, G. Palitta, R. Gazzola, P. C. Parodi, and F. Leone. "Limb trauma: the use of an advanced wound care device in the treatment of full-thickness wounds." Strategies in Trauma and Limb Reconstruction 8, no. 2 (July 30, 2013): 111–15. http://dx.doi.org/10.1007/s11751-013-0165-8.

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25

Mckee, Jessica L., Prasanna Lakshminarasimhan, Ian Atkinson, Anthony J. LaPorta, and Andrew W. Kirkpatrick. "Evaluation of Skin Damage from Accidental Removal of a Hemostatic Wound Clamp (The iTClamp)." Prehospital and Disaster Medicine 32, no. 6 (August 24, 2017): 651–56. http://dx.doi.org/10.1017/s1049023x17006926.

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AbstractBackgroundControlling bleeding early in the prehospital and military setting is an extremely important and life-saving skill. Wound clamping is a newly introduced technique that may augment both the effectiveness and logistics of wound packing with any gauze product. As these devices may be inadvertently removed, the potential consequences of such were examined in a simulated, extreme, inadvertent disengagement.MethodsThe wound clamp used was an iTClamp (Innovative Trauma Care; Edmonton, Alberta, Canada) that was applied and forcefully removed (skin-pull) from the skin of both a human cadaver and swine. Sixty skin-pull tests were sequentially performed to measure the pull weight required to remove the device, any potential skin and device damage, how the device failed, and if the device could be re-applied.ResultsObservations of the skin revealed that other than the expected eight small needle holes from device application, no other damage to the skin was sustained in 98.3% of cases. Conversely, of the 60 devices pulled, 93.3% of the devices sustained no damage and all could be re-applied. Four (6.7%) of the devices remained in place despite a maximum pull weight >22lbF (pound-force). The mean pull weights for pin bar pull were (lbF): vertical 9.2 (SD=5.0); perpendicular 2.5 (SD=1.7); and parallel 5.3 (SD=3.1). For the encompassed pull position group, mean pull weights were (lbF): vertical 5.7 (SD=2.3); perpendicular 3.0 (SD=2.5); and parallel 14.5 (SD=3.5). The overall mean for all groups was 6.7 (SD=5.2). The two main reasons that the iTClamp was pulled off were because the friction lock let go or the needles slipped out of one side of the skin due to the angle of the pull.ConclusionInadvertent, forcible removal of the iTClamp created essentially no skin damage seen when the wound clamp was forcibly removed from either cadaver or swine models in a variety of positions and directions. Thus, the risks of deployment in operational environments do not seem to be increased.MckeeJL, LakshminarasimhanP, AtkinsonI, LaPortaAJ, KirkpatrickAW. Evaluation of skin damage from accidental removal of a hemostatic wound clamp (the iTClamp). Prehosp Disaster Med. 2017;32(6):651–656.
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Suyanto, Suyanto, and Ahmad Ikhlasul Amal. "MODERN WOUND IRRIGATION DEVICE (MWID) REDUCE THE NUMBER OF BACTERIA IN DIABETIC ULCER PATIENTS." INDONESIAN NURSING JOURNAL OF EDUCATION AND CLINIC (INJEC) 2, no. 1 (August 31, 2017): 105. http://dx.doi.org/10.24990/injec.v2i1.125.

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Background and Purpose: One of the micro-vascular complications in patients with diabetes mellitus is a diabetic ulcer. One of he goals of care in diabetic ulcers is to reduce infection in the wound area by doing a cleansing method particularly utilizing irrigation techniques. Irrigation technique aims to reduce the number of bacteria in the wound, so that the inflammatory process is expected to be more quickly achieved. Many diabetic ulcer care-related research but researches on irrigation tools on diabetic ulcers are very minimal. This study aims to determine the effect of Modern Wound Irrigation Device (MWID) to decrease the amount of bacteria on patients with diabetic ulcers. Method: This study was utilized quasi-experimental post test only with control group design. A total of 20 respondents in this study were divided into 10 respondents for intervention group that was given wound care using MWID. 10 respondents as control group that was given manual irrigation wound care. Results: The average number of bacteria in intervention group is 30,4x109 colonies/ml, while the average number of bacteria for control group is 59x109 colonies/ml. Analysis with independent t test was found that there is no significant difference between the average number of bacteria on the intervention and control groups with p value of (0.001 < 0.005). Conclusion and recommendation: the use of MWID for current wound irrigation is proven can reduce the amount of bacteria on diabetic ulcers as compared with manual irrigation technique. Further developmental researches utilize MWID tool is to modify the output of irrigation to reduce anaerobic bacteria for gangrene wound.Key words: Diabetic Ulcer, Wound irrigation, amount of bacteria
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Sun, Xianyou, Yanchi Zhang, Chiyu Ma, Qunchen Yuan, Xinyi Wang, Hao Wan, and Ping Wang. "A Review of Recent Advances in Flexible Wearable Sensors for Wound Detection Based on Optical and Electrical Sensing." Biosensors 12, no. 1 (December 23, 2021): 10. http://dx.doi.org/10.3390/bios12010010.

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Chronic wounds that are difficult to heal can cause persistent physical pain and significant medical costs for millions of patients each year. However, traditional wound care methods based on passive bandages cannot accurately assess the wound and may cause secondary damage during frequent replacement. With advances in materials science and smart sensing technology, flexible wearable sensors for wound condition assessment have been developed that can accurately detect physiological markers in wounds and provide the necessary information for treatment decisions. The sensors can implement the sensing of biochemical markers and physical parameters that can reflect the infection and healing process of the wound, as well as transmit vital physiological information to the mobile device through optical or electrical signals. Most reviews focused on the applicability of flexible composites in the wound environment or drug delivery devices. This paper summarizes typical biochemical markers and physical parameters in wounds and their physiological significance, reviews recent advances in flexible wearable sensors for wound detection based on optical and electrical sensing principles in the last 5 years, and discusses the challenges faced and future development. This paper provides a comprehensive overview for researchers in the development of flexible wearable sensors for wound detection.
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28

Pasquier, Pierre, Brice Malgras, and Stéphane Mérat. "Application of negative-pressure wound therapy in improvised explosive device–related pelviperineal injuries." Journal of Trauma and Acute Care Surgery 73, no. 6 (December 2012): 1630. http://dx.doi.org/10.1097/ta.0b013e3182751bad.

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Koehler, Christian, Andreas D. Niederbichler, Florian J. Jung, Thomas Scholz, Ludwig Labler, Daniel Perez, Abed Jandali, Maurice Comber, Walter Kuenzi, and Volker Wedler. "Wound Therapy Using the Vacuum-Assisted Closure Device: Clinical Experience with Novel Indications." Journal of Trauma: Injury, Infection, and Critical Care 65, no. 3 (September 2008): 722–31. http://dx.doi.org/10.1097/01.ta.0000249295.82527.19.

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Hatch, David, and Michael Lavor. "Decreasing Pain and Increasing the Rate of Chronic Wound Closure With the Use of a Noninvasive Bioelectronic Medical Device: A Case Series." Wounds : a compendium of clinical research and practice 33, no. 5 (May 10, 2021): 119–26. http://dx.doi.org/10.25270/wnds/2021.119126.

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Introduction. Chronic wounds are a source of significant morbidity. Medical and scientific efforts are ongoing to further therapeutic modalities improving pain scores and augmenting healing while decreasing complications and reducing the social and economic burden of wounds. Electrical current therapy, or electrical stimulation (ES), has been shown to decrease and modulate both acute and chronic pain; however, understanding of the role of ES in wound closure is limited. Objective. This single-center case series reports use of a topical ultrahigh frequency ES (UHF-ES) therapy to decrease wound pain and improve the rate of closure in difficult-to-heal wounds in 9 patients. Materials and Methods. Initially, each patient underwent individualized care of their chronic wounds for a minimum of 8 weeks, after which adjunct UHF-ES therapy was provided 3 times per week for an average of 8 additional weeks. Wound size and pain level were documented for the period before and after UHF-ES. Results. Overall, pain improved across the 9 patients. One patient was insensate, and another experienced an increase in pain during treatment. Of the 8 patients with sensation, 7 (88%) experienced a decrease in wound pain, with an average 3.4-point reduction per 10-point visual analog scale. Average pain level was 4.14 before treatment and 0.71 after. The average wound size was 5.70 cm2 ± 5.23 cm2 approximately 8 weeks before the initiation of treatment, 4.34 cm2 ± 4.51 cm2 at the time of treatment, and 1.2 cm2 ± 1.75 cm2 at the conclusion of treatment. The average percentage of wound closure with individualized wound care alone was 23.77%, which increased to 64.58% with the addition of UHF-ES therapy. The weekly percentage of wound closure was statistically significant (P = .0027) between the 2 treatment methods. Conclusions. While additional research into the use of ES (namely, UHF-ES in wound healing) is warranted, the device reported herein may be an effective, safe, and low-cost adjunct treatment in the care of chronic, difficult-to-heal wounds.
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Janssen, Alexandra HJ, Johannes A. Wegdam, Tammo S. de Vries Reilingh, Anne M. Eskes, and Hester Vermeulen. "Negative pressure wound therapy for patients with hard-to-heal wounds: a systematic review." Journal of Wound Care 29, no. 4 (April 2, 2020): 206–12. http://dx.doi.org/10.12968/jowc.2020.29.4.206.

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Objective: Despite the lack of evidence, negative pressure wound therapy (NPWT) is commonly used in patients with hard-to-heal wounds. In our medical centre, one third of patients with abdominal wounds infected postoperatively end this therapy prematurely due to negative experiences and prefer standard wound care. This study was designed to explore the effects of NPWT on quality of life (QoL). Method: A search from 2000 to 2019 in eight databases was performed to identify qualitative studies of patients treated with NPWT. Studies were selected by two independent reviewers, who appraised the methodological quality, extracted and structured the data and performed content analysis. Results: A total of five qualitative studies with good methodological quality, incorporating 51 individual patients, were included. After content analysis, four major themes emerged: reduced freedom of movement caused by an electric device; decreased self-esteem; increased social and professional dependency; and gaining self-control. Conclusion: NPWT has major effects on the physical, psychological and social domains of QoL. Knowledge of these effects may lead to improved treatment decisions for patients with hard-to-heal wounds regarding use of NPWT or standard wound care.
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Queen, Douglas. "Impact of COVID ‐19 on the medical device companies who serve wound care." International Wound Journal 18, no. 3 (May 11, 2021): 247–48. http://dx.doi.org/10.1111/iwj.13609.

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Kim, Hosan, Soon Park, Greggory Housler, Vanessa Marcel, Sue Cross, and Mina Izadjoo. "An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device." Military Medicine 181, no. 5S (May 2016): 184–90. http://dx.doi.org/10.7205/milmed-d-15-00157.

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Leonhard, Lucas, Joseph Roche, Aaron Wieland, and G. Mark Pyle. "The Temporoparietal Fascia Flap is an Effective Strategy for Cochlear Implant Wound Coverage." Annals of Otology, Rhinology & Laryngology 129, no. 2 (September 27, 2019): 135–41. http://dx.doi.org/10.1177/0003489419877429.

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Objective: To report the rate of major soft tissue complications after cochlear implantation and to describe the use of the temporoparietal fascia (TPF) flap for such complications. Study Design: Retrospective case series. Setting: Tertiary care, University Hospital. Subjects and Methods: Chart review of all patients who underwent cochlear device implantation over a 5-year period to identify patients and to determine the rate of soft tissue complications. Five patients with major soft tissue complications underwent TPF flap with device salvage or explantation/reimplantation. Results: The rate of major skin complications was 6 out of 281 (2.1%) over 5 years, with 5 patients undergoing TPF flap. The average follow-up was 25.8 months (range, 5-58 months). TPF flap represented the definitive, successful solution for all 5 patients. One postoperative hematoma occurred after TPF flap, with no long-term sequelae. The average hospital length of stay was 2.2 nights (range, 1-5 nights). One patient required IV antibiotics for 4 weeks; the remaining patients were treated with a postoperative course of oral antibiotics. The original device remained in place for 4 patients, while one case required device explantation and staged re-implantation. Post-TPF flap hearing results were equal to if not superior to their preoperative results. Conclusion: Major soft tissue complications following cochlear device implantation are rare. The temporoparietal fascia flap is an excellent option for reconstruction of device site soft tissue dehiscences when local wound care and primary closure are not sufficient, and can potentially prevent explantation of a functional implant.
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Kuan, Ya-Ting, Tze-Fang Wang, Chao-Yu Guo, Fu-In Tang, and I.-Ching Hou. "Wound Care Knowledge, Attitudes, and Practices and Mobile Health Technology Use in the Home Environment: Cross-Sectional Survey of Social Network Users." JMIR mHealth and uHealth 8, no. 3 (March 26, 2020): e15678. http://dx.doi.org/10.2196/15678.

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Background Injury causing wounds is a frequent event. Inadequate or inappropriate treatment of injuries can threaten individual health. However, little is known about wound care knowledge, attitudes, and practices and mobile health (mHealth) use in the home environment in Taiwan. Objective This study aimed to evaluate wound care knowledge, attitudes, and practices and mHealth technology use among social network users. Methods A cross-sectional survey on social media platforms was conducted on adults aged 20 years and older. Data were collected from social network users in the home environment. Results A total of 361 participants were enrolled. The mHealth technology use of participants was positively correlated with wound care knowledge (r=.132, P=.01), attitudes (r=.239, P<.001), and practices (r=.132, P=.01). Participants did not have adequate knowledge (correct rate 69.1%) and were unfamiliar with the guidelines of proper wound care (correct rate 74.5%). Most participants had positive attitudes toward wound care and mHealth technology use. A total of 95.6% (345/361) of participants perceived that the use of mHealth technology can improve wound care outcomes, and 93.9% (339/361) perceived that wound care products should be optimized to be used with a mobile device. However, 93.6% (338/361) of participants had no experience using mHealth technology for wound care. Conclusions Our study shows the potential of mHealth technology to enhance wound care knowledge among social network users. Thus, government agencies and medical institutions in Taiwan should provide easy-to-use information products that enhance wound care knowledge, promote adequate behavior toward wound care, and prevent unpredictable or undesirable outcomes.
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Wikkeling, Marald, Judith Mans, and Timothy Styche. "Single use negative pressure wound therapy in vascular patients: clinical and economic outcomes." Journal of Wound Care 30, no. 9 (September 2, 2021): 705–10. http://dx.doi.org/10.12968/jowc.2021.30.9.705.

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Objective: Surgical site complications (SSCs) such as dehiscence and infection are a common issue within vascular surgeries and are a key concern to payers and clinicians. It is estimated that occurrence of complications in vascular surgery can increment length of stay by 9.72 days and costs by £3776 per episode. The objective of this research was to determine the clinical and economic impact of the prophylactic use of single use negative pressure wound therapy (sNWPT) in postoperative femoral endarterectomy incisions within a single centre in the Netherlands. Method: Data were extracted retrospectively from the medical notes of patients consecutively treated for femoral endarterectomy between January 2013 and December 2019 in a single centre in the Netherlands. Since August 2016, patients were treated with the sNPWT device and their data were compared with that of patients treated before the introduction of the device. Data were extracted on SSCs and associated healthcare resource use, with comparisons made between the two patient groups. Results: The study included a cohort of 108 patients. Data of patients treated by standard care (n=64) showed 32 (50%) patients developed complications. This reduced significantly in patients treated with the sNPWT device (n=44) of whom eight (18.2%) developed a postoperative complication (p=0.0011). Average postoperative costs per patient were €3119 for those in the standard care group and €2630 where the sNPWT device was used. Conclusion: sNPWT provided clinical and economic benefits over standard care in the treatment of femoral endarterectomy patients, significantly reducing rate of complication and their associated costs.
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DasGupta, Tracey, Laura Rashleigh, Kevin Zhou, Liz Williamson, Susan Schneider, Sukaina Muhammad, Manry Xu, et al. "Use of a Fluorescence Imaging Device to Detect Elevated Bacterial Loads, Enhance Antimicrobial Stewardship, and Increase Communication Across Inpatient Complex Wound Care Teams." Wounds: a compendium of clinical research and practice 34, no. 8 (2022): 201–8. http://dx.doi.org/10.25270/wnds/21076.

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Introduction. Wounds are increasing in number and complexity within the hospital inpatient system, and coordinated and dedicated wound care along with the use of emerging technologies can result in improved patient outcomes. Objective. This prospective implementation study at 2 hospital inpatient sites examines the effect of bedside fluorescence imaging of wounds in the detection of elevated bacterial loads and its location in/around the wound on the inpatient wound population. Materials and Methods. Clinical assessment and fluorescence imaging assessments were performed on 26 wounds in 21 patients. Treatment plans were recorded after the clinical assessment and again after fluorescence imaging, and any alterations made to the treatment plans after imaging were noted. Results. Prior to fluorescence imaging, antimicrobial use in this patient population was common. An antimicrobial dressing, a topical antibiotic, or an oral antibiotic was prescribed in 23 wounds (88% of assessments), with antimicrobial dressings prescribed 73% of the time. Based on clinical assessment, more than half of the treated wounds were deemed negative for suspected infection. In 12 of 26 wounds, the fluorescence imaging information on bacterial presence had the potential to prompt a change in whether an antimicrobial dressing was prescribed. Five of these 12 wounds were fluorescence imaging-positive and an antimicrobial drug was not prescribed, whereas 7 of the 12 wounds were negative upon fluorescence imaging and clinical assessment but antimicrobial dressing was prescribed. Overall, fluorescence imaging detected 70% more wounds, with bacterial fluorescence indicating elevated bacterial loads, compared with clinical assessment alone, and use of imaging resulted in altered treatment plans in 35% of cases. Conclusions. Fluorescence imaging can aid in antimicrobial stewardship goals by supporting evidence-based decision-making at the point of care. In addition, use of such imaging resulted in increased communication, enhanced efficiency, and improved continuity of care between wound care providers and hospital sites.
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Baxter, Ronald D., Jeffrey E. Carter, Christopher K. Craig, Jeffrey W. Williams, and James H. Holmes. "92 Improved Burn Healing Classification via Artificial Intelligence." Journal of Burn Care & Research 41, Supplement_1 (March 2020): S60—S61. http://dx.doi.org/10.1093/jbcr/iraa024.095.

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Abstract Introduction Current methods of assessment for burn severity and healing potential are insufficient but this determination remains critical in providing optimal burn care. A novel device using multispectral imaging and artificial intelligence (AI) has shown prior success aiding in this process. Promising initial results of this proof-of-concept case series have been presented previously, invoking much interest from the burn care community. These results reflect the final results of this study and provide support for continued investigation with this device for the treatment of burn wounds. Methods Subjects with thermal burns were enrolled within 72 hours of injury. The goal was to enroll at least 12 burn wounds from each category of severity: 1°; superficial 2°; deep 2°; and 3°. Upon enrollment burns were imaged with the study device serially for up to 7 days post-burn. The true healing potential of each imaged burn area was determined using either healing assessment at 21 days post-burn or multiple punch biopsies of the burn wound taken at time of excision and grafting. This ground truth was used to train the AI algorithm to automatically identify the margins of non-healing burn tissue within device images. Accuracy of the study device to identify and differentiate healing and non-healing burn tissue within the captured wound area was computed. Results Data from 38 subjects with 58 total burns and 393 wound images were obtained during this study. Following completion of training, AI predictions achieved 90.7% sensitivity with 87.5% specificity in predicting non-healing burn tissue using cross-validation. Results improved throughout the study as more wound images were used in AI training (Figure 1). Conclusions The AI algorithm trained on 58 burn wounds (38 subjects) had an area under the curve of 0.955 and has continued to improve with the addition of more burn wounds. Expansion of this study has been initiated at multiple burn centers to continue collecting data for AI algorithm training. Applicability of Research to Practice These results demonstrate feasibility of utilizing AI-assisted diagnosis in burn wounds and possible application in the management of burn patients.
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Ernst, Jennifer, Murat Tanyeli, Thomas Borchardt, Moses Ojugo, Andreas Helmke, Wolfgang Viöl, Arndt F. Schilling, and Gunther Felmerer. "Effect on healing rates of wounds treated with direct cold atmospheric plasma: a case series." Journal of Wound Care 30, no. 11 (November 2, 2021): 904–14. http://dx.doi.org/10.12968/jowc.2021.30.11.904.

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Objective: The response of different critical acute and hard-to-heal wounds to an innovative wound care modality—direct application of cold atmospheric plasma (CAP)—was investigated in this clinical case series. Method: Over an observation period of two years, acute wounds with at least one risk factor for chronification, as well as hard-to-heal wounds were treated for 180 seconds three times per week with CAP. CAP treatment was additional to standard wound care. Photographs were taken for wound documentation. The wound sizes before the first CAP treatment, after four weeks, after 12 weeks and at wound closure/end of observation time were determined using image processing software, and analysed longitudinally for the development of wound size. Results: A total of 27 wounds (19 hard-to-heal and eight acute wounds) with a mean wound area of 15cm2 and a mean wound age of 49 months were treated with CAP and analysed. All (100%) of the acute wounds and 68% of the hard-to-heal wounds healed after an average treatment duration of 14.2 weeks. At the end of the observation period, 21% of hard-to-heal wounds were not yet closed but were reduced in size by >80%. In 11% of the hard-to-heal wounds (n=2) therapy failed. Conclusion: The results suggested a beneficial effect of additional CAP therapy on wound healing. Declaration of interest: This work was carried out within the research projects ‘Plasma for Life’ (funding reference no. 13FH6I04IA) with financial support from the German Federal Ministry of Education and Research (BMBF). In the past seven years AFS has provided consulting services to Evonik and has received institutional support by Heraeus, Johnson & Johnson and Evonik. There are no royalties to disclose. The Department for Trauma Surgery, Orthopaedics and Plastic Surgery received charitable donations by CINOGY GmbH. CINOGY GmbH released the di_CAP devices and electrodes for the study. WV and AH were involved in the development of the used di_CAP device (Plasmaderm, CINOGY GmbH). WV is shareholder of the outsourced start-up company CINOGY GmbH.
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Smith, N. Robinson, N. Wrightson, G. MacGowan, T. Butt, F. Oezalp, K. Gould, and S. Schueler. "27 Improving Patient Satisfaction in Wound Care of Left Ventricular Assist Device Exit Sites." Journal of Heart and Lung Transplantation 31, no. 4 (April 2012): S18. http://dx.doi.org/10.1016/j.healun.2012.01.030.

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Godwin, Zachary R., Jennifer C. Bockhold, Luke Webster, Stephanie Falwell, Laura Bomze, and Nam K. Tran. "Development of novel smart device based application for serial wound imaging and management." Burns 39, no. 7 (November 2013): 1395–402. http://dx.doi.org/10.1016/j.burns.2013.03.021.

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Mullins, Sydney, Sarah Bernardy, Marianne MacLachlan, Maureen Evans, Anna Olszewski, Kara N. Kidd, Angela Maroon, et al. "807 Implementation of an Evidence-based Wound Care Process at a Regional Burn Center Reduces Hospital Acquired Infections." Journal of Burn Care & Research 41, Supplement_1 (March 2020): S241—S242. http://dx.doi.org/10.1093/jbcr/iraa024.384.

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Abstract Introduction Central line associated blood stream infection (CLABSI) rates in burn patients exceeds the national average. The purpose of this study was to determine if implementation of an evidence-based process for wound care and central line management reduce infections. Methods A protocol for central line and wound care was developed in conjunction with another burn center with lower CLABSI rates and a care bundle, based on colorectal surgical literature. The new protocol required hand to elbow washing prior to wound care, separating the dirty and clean steps of the wound care process, changing protective gear when going from dirty to clean and performing the Hospital Acquired Infection (HAI) bundle elements separate from wound care. CLABSI and Ventilator Associated Pneumonia (VAP) rates were then compared with the previous year. Results Following implementation of the new wound care guidelines, the number of CLABSIs declined from 10 in 2017 to 2 in 2018 and 1 so far in 2019 (through August 2019). The median number of CLABSIs per 1000 days was 0 (range of 0 to 11) before the bundle and 0 (range of 0 to 4.2) after implementation of the bundle. Using the Wilcox rank sum test, there was no significant difference (p=0.09) between the CLABSI rate per 1000 device days between the time period before the bundle implementation and after the bundle implementation, however this may be due to the small sample size. Although the CLABSI rate did not show a statistically significant decrease, the proportion of positive blood cultures decreased by 50% after implementation of the bundle. The number of VAPs declined from 8 in 2017 to 6 in 2018 and so far in 2019 no VAPs have been reported (through August 2019). There was no difference in device days between groups. Conclusions Creating a wound care process that clearly defines and separates clean and dirty steps, similar to colorectal surgical bundles in the reduction of Surgical Site Infection, reduced CLABSI and HAI rates in a clinically significant, if not statistically significant way in the Burn Intensive Care Unit. Further study is needed to increase the power of this study to possibly detect statistically significant differences. Applicability of Research to Practice Implementation of an evidence-based, standardized practice for wound care improved infection rates at one regional burn center. It would be beneficial for this process to be replicated at other centers to further test correlation with infection reduction.
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Buck de Oliveira Ruiz, Paula, Nadia Antonia Aparecida Poletti, and Antônio Fernandes Costa Lima. "PROFILE OF THE PATIENTS TREATED IN A COMPREHENSIVE WOUND CARE UNIT." Cogitare Enfermagem, no. 27 (July 26, 2022): 1–10. http://dx.doi.org/10.5380/ce.v27i0.86902.

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Objective: to analyze the demographic, clinical and therapeutic profiles of the patients treated in a Comprehensive Wound Care Unit. Method: a quantitative and retrospective study that analyzed management reports and medical records of patients with chronic wounds treated at a Comprehensive Wound Care Unit in Vitória da Conquista-Bahia, Brazil. The data, collected in February 2020, were submitted to descriptive and inferential analysis, and the Chi-square test with p-value<0.05 was used for the association between variables. Results: the mean age among the 176 patients was 71.4 years old (SD±16.5). There was a statistical association between fecal incontinence and stage two Pressure Injury (p=0.018); Diabetes Mellitus and stage three Pressure Injury (p<0.001); Alzheimer’s disease and medical device-related injury (p=0.028); Diabetes Mellitus and Diabetic Ulcer (p<0.001); and between vascular insufficiency and Venous Ulcer (p<0.001). Conclusion: knowledge about the profiles provides the basis for the comprehensive assistance provided by a non-hospital unit specialized in wounds.
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Raizman, Rose, William Little, and Allie Clinton Smith. "Rapid Diagnosis of Pseudomonas aeruginosa in Wounds with Point-Of-Care Fluorescence Imaing." Diagnostics 11, no. 2 (February 11, 2021): 280. http://dx.doi.org/10.3390/diagnostics11020280.

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Pseudomonas aeruginosa (PA) is a common bacterial pathogen in chronic wounds known for its propensity to form biofilms and evade conventional treatment methods. Early detection of PA in wounds is critical to the mitigation of more severe wound outcomes. Point-of-care bacterial fluorescence imaging illuminates wounds with safe, violet light, triggering the production of cyan fluorescence from PA. A prospective single blind clinical study was conducted to determine the positive predictive value (PPV) of cyan fluorescence for the detection of PA in wounds. Bacterial fluorescence using the MolecuLight i:X imaging device revealed cyan fluorescence signal in 28 chronic wounds, including venous leg ulcers, surgical wounds, diabetic foot ulcers and other wound types. To correlate the cyan signal to the presence of PA, wound regions positive for cyan fluorescence were sampled via curettage. A semi-quantitative culture analysis of curettage samples confirmed the presence of PA in 26/28 wounds, resulting in a PPV of 92.9%. The bacterial load of PA from cyan-positive regions ranged from light to heavy. Less than 20% of wounds that were positive for PA exhibited the classic symptoms of PA infection. These findings suggest that cyan detected on fluorescence images can be used to reliably predict bacteria, specifically PA at the point-of-care.
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Wu, Yu-Feng, Yu-Chen Lin, Hung-Wei Yang, Nai-Chen Cheng, and Chao-Min Cheng. "Point-of-Care Wound Blotting with Alcian Blue Grading versus Fluorescence Imaging for Biofilm Detection and Predicting 90-Day Healing Outcomes." Biomedicines 10, no. 5 (May 22, 2022): 1200. http://dx.doi.org/10.3390/biomedicines10051200.

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Biofilm infection has been identified as a crucial factor of the pathogenesis of chronic wound, but wound biofilm diagnosis remains as an unmet clinical need. We previously proposed a modified wound blotting technique using Alcian blue staining for biofilm detection that was characterized as being non-invasive, time-saving, non-expansive, and informative for biofilm distribution. In this study, we adapted a novel Alcian blue grading method as the severity of biofilm infection for the wound blotting technique and compared its biofilm detection efficacy with MolecuLight i:X- a point-of-care florescence imaging device to detect bacteria and biofilm in wounds. Moreover, their predictive value of complete wound healing at 90 days was analyzed. When validated with wound culture results in the 53 enrolled subjects with chronic wounds, the modified wound blotting method showed a strong association with wound culture, while MolecuLight i:X only exhibited a weak association. In predicting 90-day wound outcomes, the modified wound blotting method showed a strong association (Kendall’s tau value = 0.563, p < 0.001), and the wound culture showed a moderate association (Spearman’s rho = 0.535, p < 0.001), but MolecuLight i:X exhibited no significant association (p = 0.184). In this study, modified wound blotting with the Alcian blue grading method showed superior value to MolecuLight i:X both in biofilm detection and predictive validity in 90-day wound-healing outcomes.
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Lerman, Bruce, Leslie Oldenbrook, Justin Ryu, Kenton D. Fong, and Peter J. Schubart. "The SNaP™ Wound Care System: A Case Series Using a Novel Ultraportable Negative Pressure Wound Therapy Device for the Treatment of Diabetic Lower Extremity Wounds." Journal of Diabetes Science and Technology 4, no. 4 (July 2010): 825–30. http://dx.doi.org/10.1177/193229681000400409.

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Chapman-Jones, David, and Joanne Lusher. "Possible implications and clinical value of commercially sponsored evaluations: discussion on research methodology." Journal of Wound Care 28, no. 8 (August 2, 2019): 501–9. http://dx.doi.org/10.12968/jowc.2019.28.8.501.

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This paper is written in response to a publication in the Journal of Wound Care in 2018 by Guest et al., ‘Cost-effectiveness of an electroceutical device in treating non-healing venous leg ulcers: results of an RCT’. The publication and subsequent analysis of the paper provides a vehicle for a wider debate about the care of people with wounds, including who manages the wound, how resources are allocated and the use of supplemental technologies. It also raises a further important issue regarding whether the outcomes from a single randomised controlled trial (RCT) provides a more reliable level of evidence than the findings of previous investigations involving observational trials. This article analyses the results from the cited study, comparing clinical outcomes from previous published studies, and evaluates whether a conclusion may be reached as to the most appropriate and reliable method to assess the efficacy of such medical devices used in wound care. It discusses why the assessment of clinical evidence can be a problem when there is variance of outcomes in studies which use different research methodologies. The hierarchy of evidence lies at the heart of the appraisal process; and within health-care it is common that smaller commercial companies present small-scale observational trials as evidence for the efficacy of the product they are promoting. We question whether this level of data promoted as evidence for clinical efficacy should be dismissed. Guest et al. reported that, in the UK within wound care, clinical practice is inconsistent with significant regional variations; therefore, unless clinical practice guidelines are strictly enforced in a study, which then may be unrepresentative of clinical practice, does it mean that any results produced could not be transferred to the clinical environment? We discuss the conundrum.
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Kaile, Kacie, Christian Fernandez, and Anuradha Godavarty. "Development of a Smartphone-Based Optical Device to Measure Hemoglobin Concentration Changes for Remote Monitoring of Wounds." Biosensors 11, no. 6 (May 21, 2021): 165. http://dx.doi.org/10.3390/bios11060165.

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Telemedicine (TM) can revolutionize the impact of diabetic wound care management, along with tools for remote patient monitoring (RPM). There are no low-cost mobile RPM devices for TM technology to provide comprehensive (visual and physiological) clinical assessments. Here, a novel low-cost smartphone-based optical imaging device has been developed to provide physiological measurements of tissues in terms of hemoglobin concentration maps. The device (SmartPhone Oxygenation Tool—SPOT) constitutes an add-on optical module, a smartphone, and a custom app to automate data acquisition while syncing a multi-wavelength near-infrared light-emitting diode (LED) light source (690, 810, 830 nm). The optimal imaging conditions of the SPOT device were determined from signal-to-noise maps. A standard vascular occlusion test was performed in three control subjects to observe changes in hemoglobin concentration maps between rest, occlusion, and release time points on the dorsal of the hand. Hemoglobin concentration maps were compared with and without applying an image de-noising algorithm, single value decomposition. Statistical analysis demonstrated that the hemoglobin concentrations changed significantly across the three-time stamps. Ongoing efforts are in imaging diabetic foot ulcers using the SPOT device to assess its potential as a smart health device for physiological monitoring of wounds remotely.
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Tamir, Eran, Timothy R. Daniels, Aharon Finestone, and Matityahu Nof. "Off-Loading of Hindfoot and Midfoot Neuropathic Ulcers Using a Fiberglass Cast with a Metal Stirrup." Foot & Ankle International 28, no. 10 (October 2007): 1048–52. http://dx.doi.org/10.3113/fai.2007.1048.

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Background: This study was designed to assess the effectiveness of a method of off-loading large neuropathic ulcers of the hindfoot and midfoot. The device used is composed of a fiberglass cast with a metal stirrup and a window around the ulcer. Methods: A retrospective study of 14 diabetic and nondiabetic patients was performed. All had chronic plantar hindfoot or midfoot neuropathic ulcers that failed to heal with conventional treatment methods. A fiberglass total contact cast with a metal stirrup was applied. A window was made over the ulcer to allow daily ulcer care. Results: The average duration of ulcer before application of the metal stirrup was 26 + 13.2 (range 7 to 52) months. The ulcer completely healed in 12 of the 14 patients treated. The mean time for healing was 10.8 weeks for midfoot ulcers and 12.3 weeks for heel ulcers. Complications developed in four patients: three developed superficial wounds and one developed a full-thickness wound. In three of these four patients, local wound care was initiated, and the stirrup cast was continued to complete healing of the primary ulcer. Conclusions: A fiberglass cast with a metal stirrup is an effective off-loading device for midfoot and hindfoot ulcers. It is not removable and does not depend on patient compliance. The window around the ulcer allows for daily wound care, drainage of the ulcer and the use of vacuum-assisted closure (VAC) treatment. The complication rate is comparable to that of total contact casting.
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Silva, Marcelo Henrique da, Maria Cristina Pinto de Jesus, Deíse Moura de Oliveira, and Miriam Aparecida Barbosa Merighi. "Unna's boot: experience of care of people with venous ulcers." Revista Brasileira de Enfermagem 70, no. 2 (April 2017): 349–56. http://dx.doi.org/10.1590/0034-7167-2016-0219.

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ABSTRACT Objective: to understand the experience of care of people with venous ulcers using an Unna's boot. Method: a qualitative study, based on the social phenomenology by Alfred Schütz, was carried out with 12 adults interviewed in 2015. The statements were analyzed and organized in thematic categories. Results: the following categories emerged: "Unna's boot annoyance versus wound improvement", "Difficulties for accessing care with the Unna's boot", "Care for healing and preventing recurrence", and "Receiving more attention from the healthcare professional". Conclusion: the experience of care of people using an Unna's boot revealed the annoyance caused by this device, which was overcome due to the wound improvement. However, access to care was compromised by the lack of structure at the service, frustrating the patients' expectations regarding wound healing. The issues of these people's intersubjective universe should be considered in the management of care of venous ulcers.
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