Journal articles on the topic 'Wnt inhibitors'
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Pehlivan, Melek, Ceyda Caliskan, Zeynep Yuce, and Hakkı Ogun Sercan. "Forced expression of Wnt antagonists sFRP1 and WIF1 sensitizes chronic myeloid leukemia cells to tyrosine kinase inhibitors." Tumor Biology 39, no. 5 (May 2017): 101042831770165. http://dx.doi.org/10.1177/1010428317701654.
Full textWatanabe, K., and X. Dai. "Winning WNT: Race to Wnt signaling inhibitors." Proceedings of the National Academy of Sciences 108, no. 15 (March 30, 2011): 5929–30. http://dx.doi.org/10.1073/pnas.1103102108.
Full textRogaczewski, Patryk, Michał Janiak, Kamil Borysewicz, Tadeusz Głos, Navid Ahmadi, and Łukasz Szylberg. "Clinical significancy of WNT pathway inhibition in various cancers." Journal of Education, Health and Sport 12, no. 11 (November 3, 2022): 183–91. http://dx.doi.org/10.12775/jehs.2022.12.11.024.
Full textGriffiths, Elizabeth A., Craig M. Hooker, Michael A. McDevitt, Judith E. Karp, James G. Herman, and Hetty E. Carraway. "Acute Myeloid Leukemia Is Characterized by Wnt Pathway Inhibitor Promoter Methylation." Blood 112, no. 11 (November 16, 2008): 2253. http://dx.doi.org/10.1182/blood.v112.11.2253.2253.
Full textFilipovich, Alexandra, Iris Gehrke, Simon J. Poll-Wolbeck, and Karl-Anton Kreuzer. "Physiological inhibitors of Wnt signaling." European Journal of Haematology 86, no. 6 (May 17, 2011): 453–65. http://dx.doi.org/10.1111/j.1600-0609.2011.01592.x.
Full textRomán-Gómez, José, Lucia Cordeu, Xabier Agirre, Antonio Jiménez-Velasco, Edurne San José-Eneriz, Leire Garate, María José Calasanz, Anabel Heiniger, Antonio Torres, and Felipe Prosper. "Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia." Blood 109, no. 8 (December 5, 2006): 3462–69. http://dx.doi.org/10.1182/blood-2006-09-047043.
Full textElyamany, Ghaleb, Hassan Rizwan, Ariz Akhter, Mansour S. Aljabry, Sultan Alotaibi, Mohammad A. Hameed Albalawi, Meer-Taher Shabani-Rad, Tariq Mahmood Roshan, and Adnan Mansoor. "“Losing the Brakes”—Suppressed Inhibitors Triggering Uncontrolled Wnt/ß-Catenin Signaling May Provide a Potential Therapeutic Target in Elderly Acute Myeloid Leukemia." Current Issues in Molecular Biology 45, no. 1 (January 9, 2023): 604–13. http://dx.doi.org/10.3390/cimb45010040.
Full textLi, Bo, Jinxia Liang, Feng Lu, Guandi Zeng, Jindao Zhang, Yinxing Ma, Peng Liu, Qin Wang, Qian Zhou, and Liang Chen. "Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening." Molecules 25, no. 7 (April 6, 2020): 1680. http://dx.doi.org/10.3390/molecules25071680.
Full textYe, Zhen-Nan, Feng Yuan, Jie-Qing Liu, Xing-Rong Peng, Tao An, Xue Li, Ling-Mei Kong, Ming-Hua Qiu, and Yan Li. "Physalis peruviana-Derived 4β-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo." Molecules 24, no. 6 (March 22, 2019): 1146. http://dx.doi.org/10.3390/molecules24061146.
Full textMii, Yusuke, and Masanori Taira. "Secreted Wnt “inhibitors” are not just inhibitors: Regulation of extracellular Wnt by secreted Frizzled-related proteins." Development, Growth & Differentiation 53, no. 8 (October 2011): 911–23. http://dx.doi.org/10.1111/j.1440-169x.2011.01299.x.
Full textXiao, Yao, Thiago F. Amaral, Pablo J. Ross, Delia A. Soto, Kenneth E. Diffenderfer, Aimee R. Pankonin, Surawich Jeensuk, Paula Tríbulo, and Peter J. Hansen. "Importance of WNT-dependent signaling for derivation and maintenance of primed pluripotent bovine embryonic stem cells." Biology of Reproduction 105, no. 1 (April 23, 2021): 52–63. http://dx.doi.org/10.1093/biolre/ioab075.
Full textZhong, Yu, Paula Katavolos, Trung Nguyen, Ted Lau, Jason Boggs, Amy Sambrone, David Kan, et al. "Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1." Toxicologic Pathology 44, no. 2 (December 20, 2015): 267–78. http://dx.doi.org/10.1177/0192623315621192.
Full textZhao, Yuanyuan, Leilei Tao, Jun Yi, Haizhu Song, and Longbang Chen. "The Role of Canonical Wnt Signaling in Regulating Radioresistance." Cellular Physiology and Biochemistry 48, no. 2 (2018): 419–32. http://dx.doi.org/10.1159/000491774.
Full textChang, Chun-Chun, Sheng-Feng Pan, Min-Huang Wu, Chun-Tse Cheng, Yan-Rui Su, Shinn-Jong Jiang, and Hao-Jen Hsu. "Combinatorial Virtual Screening Revealed a Novel Scaffold for TNKS Inhibition to Combat Colorectal Cancer." Biomedicines 10, no. 1 (January 10, 2022): 143. http://dx.doi.org/10.3390/biomedicines10010143.
Full textKim, Yonghyo, Myoung-Hee Kang, and Yong-Hee Cho. "API-2-Induced Cell Migration Is Overcome by Small Molecular Approaches Inhibiting β-Catenin." Current Issues in Molecular Biology 44, no. 12 (November 29, 2022): 6006–14. http://dx.doi.org/10.3390/cimb44120409.
Full textHao, Jing, Xiangzi Han, Haidong Huang, xingjiang yu, Shideng Bao, Richard Prayson, and Jennifer Yu. "DDRE-15. Sema3C SIGNALING CONFERS RESISTANCE TO Wnt INHIBITION IN GLIOBLASTOMA." Neuro-Oncology 23, Supplement_6 (November 2, 2021): vi77. http://dx.doi.org/10.1093/neuonc/noab196.299.
Full textPredes, Danilo, Luiz F. S. Oliveira, Laís S. S. Ferreira, Lorena A. Maia, João M. A. Delou, Anderson Faletti, Igor Oliveira, et al. "The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation." Cancers 11, no. 12 (December 7, 2019): 1968. http://dx.doi.org/10.3390/cancers11121968.
Full textKazanskaya, O., A. Glinka, and C. Niehrs. "The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning." Development 127, no. 22 (November 15, 2000): 4981–92. http://dx.doi.org/10.1242/dev.127.22.4981.
Full textThorne, Curtis A., Bonnie Lafleur, Michelle Lewis, Alison J. Hanson, Kristin K. Jernigan, David C. Weaver, Kari A. Huppert, et al. "A Biochemical Screen for Identification of Small-Molecule Regulators of the Wnt Pathway Using Xenopus Egg Extracts." Journal of Biomolecular Screening 16, no. 9 (August 21, 2011): 995–1006. http://dx.doi.org/10.1177/1087057111416657.
Full textKulak, Ozlem, Hua Chen, Brody Holohan, Xiaofeng Wu, Huawei He, Dominika Borek, Zbyszek Otwinowski, et al. "Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells." Molecular and Cellular Biology 35, no. 14 (May 4, 2015): 2425–35. http://dx.doi.org/10.1128/mcb.00392-15.
Full textMa, Fen, Seiji Arai, Keshan Wang, Carla Calagua, Amanda R. Yuan, Larysa Poluben, Zhongkai Gu, et al. "Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer." Cancer Research 82, no. 8 (February 7, 2022): 1518–33. http://dx.doi.org/10.1158/0008-5472.can-21-1807.
Full textWu, Christina C. N., Michael Y. Choi, Fitzgerald Lao, Thomas J. Kipps, and Dennis A. Carson. "Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib." Blood 122, no. 21 (November 15, 2013): 5306. http://dx.doi.org/10.1182/blood.v122.21.5306.5306.
Full textCruciat, C. M., and C. Niehrs. "Secreted and Transmembrane Wnt Inhibitors and Activators." Cold Spring Harbor Perspectives in Biology 5, no. 3 (October 19, 2012): a015081. http://dx.doi.org/10.1101/cshperspect.a015081.
Full textWang, Siqing, Lei Shi, Hongwei Xu, Chunjiao Xu, Maurizio Zangari, Guido J. Tricot, and Fenghuang Zhan. "Combination of ATRA with a COX2 Inhibitor Induces Synergistic Effects On RARalpha2-Expressing Multiple Myeloma (MM) Cells." Blood 114, no. 22 (November 20, 2009): 2809. http://dx.doi.org/10.1182/blood.v114.22.2809.2809.
Full textZhang, Na, Junquan Lin, Jiah Shin Chin, Christian Wiraja, Chenjie Xu, Duncan Angus McGrouther, and Sing Yian Chew. "Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush." Journal of Tissue Engineering 13 (January 2022): 204173142210874. http://dx.doi.org/10.1177/20417314221087417.
Full textGunn, W. Grady, Ulf Krause, Narae Lee, and Carl A. Gregory. "Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma–induced bone disease in a novel murine plasmacytoma xenograft model." Blood 117, no. 5 (February 3, 2011): 1641–51. http://dx.doi.org/10.1182/blood-2010-09-308171.
Full textWeich, Alexander, Dorothee Rogoll, Sophia Gawlas, Lars Mayer, Wolfgang Weich, Judit Pongracz, Theodor Kudlich, Alexander Meining, and Michael Scheurlen. "Wnt/β-Catenin Signaling Regulates CXCR4 Expression and [68Ga] Pentixafor Internalization in Neuroendocrine Tumor Cells." Diagnostics 11, no. 2 (February 22, 2021): 367. http://dx.doi.org/10.3390/diagnostics11020367.
Full textFuentes, Rolly Garnace, Gio Martin A. Ocfemia, and Galileo Gregory Abrasaldo. "Antibacterial and Zebrafish-based Screening for Wnt Signal Inhibitory Activities of Syzygium polycephaloides (C.B. Robb. Merr.) Bark Extracts." ASM Science Journal 15 (May 17, 2021): 1–6. http://dx.doi.org/10.32802/asmscj.2021.438.
Full textKavalerchik, Edward, Jason Gotlib, Ifat Geron, Annelie Abrahamsson, Wolfgang Wrasidlo, Daniel Goff, Desheng Lu, et al. "Inhibition of Chronic Myelogenous Leukemia Stem Cells with Novel Wnt Antagonists." Blood 108, no. 11 (November 16, 2006): 238. http://dx.doi.org/10.1182/blood.v108.11.238.238.
Full textKim, Anthony S., Daniel H. Lowenstein, and Samuel J. Pleasure. "Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon." Mechanisms of Development 103, no. 1-2 (May 2001): 167–72. http://dx.doi.org/10.1016/s0925-4773(01)00342-2.
Full textJackson, Sadhana, Amelie Vezina, Nabanita Kundu, and Robert Robey. "BIOL-01. THE RELATIONSHIP OF BRAIN ENDOTHELIAL WNT SIGNAL INHIBITION ON BLOOD-TUMOR BARRIER INTEGRITY." Neuro-Oncology 23, Supplement_1 (June 1, 2021): i3. http://dx.doi.org/10.1093/neuonc/noab090.009.
Full textNemade, Harshal, Aviseka Acharya, Umesh Chaudhari, Erastus Nembo, Filomain Nguemo, Nicole Riet, Hinrich Abken, Jürgen Hescheler, Symeon Papadopoulos, and Agapios Sachinidis. "Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells." Cells 9, no. 3 (February 27, 2020): 554. http://dx.doi.org/10.3390/cells9030554.
Full textSonderegger, S., P. Haslinger, A. Sabri, J. V. Otten, C. Leisser, C. Fiala, and M. Knofler. "145. WINGLESS (WNT) 3A INDUCES TROPHOBLAST MIGRATION AND MATRIX METALLOPROTEINASE-2 SECRETION THROUGH CANONICAL WNT SIGNALLING AND PROTEIN KINASE B/AKT ACTIVATION." Reproduction, Fertility and Development 22, no. 9 (2010): 63. http://dx.doi.org/10.1071/srb10abs145.
Full textTan, Mengtian, Lai Jiang, Yinglei Li, and Wei Jiang. "Dual Inhibition of BMP and WNT Signals Promotes Pancreatic Differentiation from Human Pluripotent Stem Cells." Stem Cells International 2019 (December 1, 2019): 1–15. http://dx.doi.org/10.1155/2019/5026793.
Full textJanovská, Pavlína, Emmanuel Normant, Hari Miskin, and Vítězslav Bryja. "Targeting Casein Kinase 1 (CK1) in Hematological Cancers." International Journal of Molecular Sciences 21, no. 23 (November 27, 2020): 9026. http://dx.doi.org/10.3390/ijms21239026.
Full textKleszcz, Robert, and Jarosław Paluszczak. "The Wnt Signaling Pathway Inhibitors Improve the Therapeutic Activity of Glycolysis Modulators against Tongue Cancer Cells." International Journal of Molecular Sciences 23, no. 3 (January 23, 2022): 1248. http://dx.doi.org/10.3390/ijms23031248.
Full textAndrey Voronkov and Stefan Krauss. "Wnt/beta-Catenin Signaling and Small Molecule Inhibitors." Current Pharmaceutical Design 19, no. 4 (December 10, 2012): 634–64. http://dx.doi.org/10.2174/1381612811306040634.
Full textVoronkov, Andrey, and Stefan Krauss. "Wnt/beta-Catenin Signaling and Small Molecule Inhibitors." Current Pharmaceutical Design 19, no. 4 (February 1, 2013): 634–64. http://dx.doi.org/10.2174/138161213804581837.
Full textRay, Katrina. "Therapeutic strategies for cholangiocarcinoma—wishing on WNT inhibitors?" Nature Reviews Gastroenterology & Hepatology 12, no. 4 (March 10, 2015): 187. http://dx.doi.org/10.1038/nrgastro.2015.39.
Full textXu, Congdi, Xinyu Hu, Yantao Fan, Ling Zhang, Zhengliang Gao, and Chunhui Cai. "Wif1 Mediates Coordination of Bone Morphogenetic Protein and Wnt Signaling in Neural and Glioma Stem Cells." Cell Transplantation 31 (January 2022): 096368972211345. http://dx.doi.org/10.1177/09636897221134540.
Full textKoo, Bon-Kyoung, Johan H. van Es, Maaike van den Born, and Hans Clevers. "Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia." Proceedings of the National Academy of Sciences 112, no. 24 (May 28, 2015): 7548–50. http://dx.doi.org/10.1073/pnas.1508113112.
Full textShen, Chen, Anmada Nayak, Ricardo A. Melendez, Daniel T. Wynn, Joshua Jackson, Ethan Lee, Yashi Ahmed, and David J. Robbins. "Casein Kinase 1α as a Regulator of Wnt-Driven Cancer." International Journal of Molecular Sciences 21, no. 16 (August 18, 2020): 5940. http://dx.doi.org/10.3390/ijms21165940.
Full textBravo, Dalibel, Kristen L. Shogren, Scott M. Riester, Eric R. Wagner, James L. Herrick, Scott H. Okuno, Michael J. Yaszemski, and Avudaiappan Maran. "Wnt antagonists in osteosarcoma patients." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 10531. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.10531.
Full textFu, Wen-bin, Wei Eric Wang, and Chun-yu Zeng. "Wnt signaling pathways in myocardial infarction and the therapeutic effects of Wnt pathway inhibitors." Acta Pharmacologica Sinica 40, no. 1 (July 12, 2018): 9–12. http://dx.doi.org/10.1038/s41401-018-0060-4.
Full textZhang, Hao, Ya Bao, Chenglong Liu, Jianqi Li, Di Zhu, and Qingwei Zhang. "Recent advances in β-catenin/BCL9 protein–protein interaction inhibitors." Future Medicinal Chemistry 13, no. 10 (May 2021): 927–40. http://dx.doi.org/10.4155/fmc-2020-0357.
Full textHao, Jing. "Abstract 5348: SEMA3C signaling confers resistance to Wnt Inhibition in glioblastoma." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5348. http://dx.doi.org/10.1158/1538-7445.am2022-5348.
Full textCai, Zhen, and Jie Hu. "Construction of Wif1-IgG1/Fc Recombinant Vector and Characterization of Its Expression in CHO Cells." Blood 108, no. 11 (November 16, 2006): 5207. http://dx.doi.org/10.1182/blood.v108.11.5207.5207.
Full textA Harris, Jon, and Edward A Beutler. "Therapeutic window for Wnt-driven cancers: Role of Porcupine inhibitor." American Journal of BioMedicine 2, no. 2 (May 14, 2014): 78–86. http://dx.doi.org/10.18081/2333-5106/014-01/78-86.
Full textFunck-Brentano, Thomas, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H. Lerner, Antti Koskela, Juha Tuukkanen, Martine Cohen-Solal, Sofia Movérare-Skrtic, and Claes Ohlsson. "Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice." Journal of Endocrinology 238, no. 1 (July 2018): 13–23. http://dx.doi.org/10.1530/joe-18-0153.
Full textBisson, Sarah-Kim, Roth-Visal Ung, and Fabrice Mac-Way. "Role of the Wnt/β-Catenin Pathway in Renal Osteodystrophy." International Journal of Endocrinology 2018 (2018): 1–15. http://dx.doi.org/10.1155/2018/5893514.
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