Relevant bibliographies by topics / Winsaam

Academic literature on the topic 'Winsaam'

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Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Winsaam"

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Stefanovski, Darko, Peter J. Moate, and Raymond C. Boston. "WinSAAM: a windows-based compartmental modeling system." Metabolism 52, no. 9 (September 2003): 1153–66. http://dx.doi.org/10.1016/s0026-0495(03)00144-6.

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Park, Hyunjin, and Michael H. Green. "Parameter identifiability and Extended Multiple Studies Analysis of a compartmental model for human vitamin A kinetics: fixing fractional transfer coefficients for the initial steps in the absorptive process." British Journal of Nutrition 111, no. 6 (November 11, 2013): 1004–10. http://dx.doi.org/10.1017/s0007114513003450.

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In the existing compartmental models of human vitamin A metabolism, parameters related to the absorption of the isotopic oral dose have not been well identified. We hypothesised that fixing some poorly identified parameters related to vitamin A absorption would improve parameter identifiability and add statistical certainty to such models. In the present study, data for serum vitamin A kinetics in nine subjects given [2H8]retinyl acetate orally and a model with absorption fixed at 75 % were used to test this hypothesis. In addition to absorption efficiency, we fixed two other fractional transfer coefficients: one representing the initial processing of the ingested dose and the other representing the direct secretion of retinol bound to retinol-binding protein (RBP) from enterocytes into the plasma. The Windows version of Simulation, Analysis and Modeling software (WinSAAM) was used to fit serum tracer data v. time for each subject. Then, a population model was generated by WinSAAM's Extended Multiple Studies Analysis. All the parameters had fractional standard deviations < 0·5, and none of the pairs of parameters had a correlation coefficient >0·8 (accepted criteria for well-identified parameters). Similar to the values predicted by the original model, total traced mass for retinol was 1160 (sd 468) μmol, and the time for retinol to appear in the plasma bound to RBP was 31·3 (sd 4·4) h. In conclusion, we suggest that this approach holds promise for advancing compartmental modelling of vitamin A kinetics in humans when the dose must be administered orally.
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Green, Michael H. "Evaluation of the “Olson Equation”, an Isotope Dilution Method for Estimating Vitamin A Stores." International Journal for Vitamin and Nutrition Research 84, Supplement 1 (December 1, 2014): 9–15. http://dx.doi.org/10.1024/0300-9831/a000181.

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Isotope dilution methods have been successfully used to estimate vitamin A status in human populations as well as to evaluate the impact of vitamin A interventions. The most commonly applied isotope dilution method is the retinol isotope dilution technique, which is based on the 1989 “Olson equation” for estimating total body vitamin A stores (sometimes equated to liver vitamin A) after an oral dose of labeled vitamin A. The equation relies on several factors related to absorption and retention of the dose, the equilibration of label in plasma vs. liver, and timing of a blood sample for measurement of labeled vitamin A. Here, the assumptions underlying these factors are discussed, and new results based on applying model-based compartmental analysis [specifically, the Simulation, Analysis and Modeling software (WinSAAM)] to data on retinol kinetics in humans are summarized. A simplification of the Olson equation, in which plasma tracer is measured 3 days after administration of the oral dose and several factors are eliminated, is presented. The potential usefulness of the retinol isotope dilution technique for setting vitamin A requirements and assessing vitamin A status in children, as well as the confounding effects of inflammation and likely variability in vitamin A absorption, are also discussed.
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Cao, Sisi, Meryl E. Wastney, Pamela J. Lachcik, Hui-Hui Xiao, Connie M. Weaver, and Man-Sau Wong. "Both Oleanolic Acid and a Mixture of Oleanolic and Ursolic Acids Mimic the Effects of Fructus ligustri lucidi on Bone Properties and Circulating 1,25-Dihydroxycholecalciferol in Ovariectomized Rats." Journal of Nutrition 148, no. 12 (November 6, 2018): 1895–902. http://dx.doi.org/10.1093/jn/nxy242.

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ABSTRACT Background Oleanolic acid (OA) and ursolic acid (UA) are major chemical constituents found in Fructus ligustri lucidi (FLL), a Chinese herb previously shown to increase bone properties and modulate calcium-vitamin D metabolism in rats. OA and UA have been reported to exert osteoprotective effects in vitro. Objective The present study was designed to determine whether OA or OA + UA mimicked the effects of FLL on bone and calcium homeostasis using ovariectomized rats. Methods Three-month-old ovariectomized Sprague-Dawley rats were stabilized for 2 mo and randomly assigned to 4 groups offered the same amount (15–17 g/d) of a control diet or experimental diets containing FLL (18.8 g/kg), OA (0.67 g/kg), or OA (0.67 g/kg) + UA (0.22 g/kg) for 6 wk. Serum was obtained for measurement of 1,25-dihydroxycholecalciferol [1,25(OH)2D3] and bones were collected for micro-CT analysis. Calcium balance was measured at weeks 1 and 6. A calcium kinetic study using 45Ca was conducted at week 6 and modeled using WinSAAM software. Results Compared with the control group, rats fed the FLL-, OA-, and OA + UA-enriched diets had better bone properties and 51%, 31%, and 27% higher serum 1,25(OH)2D3 concentrations at week 6, respectively. These variables did not differ between the treatments. Calcium balance was not affected by diet at either week 1 or week 6. Kinetic modeling predicted that FLL and OA + UA diet-fed rats had 9% and 15% less endogenous excretion of calcium, respectively, compared with the control group. All 3 treatments resulted in a higher calcium mass of compartment 3 because of changes in transfer rate between compartments 2 and 3, and were positively associated with the serum 1,25(OH)2D3 concentration (R2 = 0.28; P < 0.01). Conclusion Similar to FLL, OA and OA + UA increase bone properties, serum 1,25(OH)2D3 concentration, and calcium use in ovariectomized rats, suggesting their potential role in management of osteoporosis.
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Ford, Jennifer Lynn, Joanne Balmer Green, Marjorie J. Haskell, Shaikh M. Ahmad, Dora Inés Mazariegos Cordero, Anthony Oxley, Reina Engle-Stone, Georg Lietz, and Michael H. Green. "Use of Model-Based Compartmental Analysis and a Super-Child Design to Study Whole-Body Retinol Kinetics and Vitamin A Total Body Stores in Children from 3 Lower-Income Countries." Journal of Nutrition 150, no. 2 (September 18, 2019): 411–18. http://dx.doi.org/10.1093/jn/nxz225.

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ABSTRACT Background Model-based compartmental analysis has been used to describe and quantify whole-body vitamin A metabolism and estimate total body stores (TBS) in animals and humans. Objectives We applied compartmental modeling and a super-child design to estimate retinol kinetic parameters and TBS for young children in Bangladesh, Guatemala, and the Philippines. Methods Children ingested [13C10]retinyl acetate and 1 or 2 blood samples were collected from each child from 6 h to 28 d after dosing. Temporal data for fraction of dose in plasma [13C10]retinol were modeled using WinSAAM software and a 6-component model with vitamin A intake included as weighted data. Results Model-predicted TBS was 198, 533, and 1062 μmol for the Bangladeshi (age, 9–17 mo), Filipino (12–18 mo), and Guatemalan children (35–65 mo). Retinol kinetics were similar for Filipino and Guatemalan groups and generally faster for Bangladeshi children, although fractional transfer of plasma retinol to a larger exchangeable storage pool was the same for the 3 groups. Recycling to plasma from that pool was ∼2.5 times faster in the Bangladeshi children compared with the other groups and the recycling number was 2–3 times greater. Differences in kinetics between groups are likely related to differences in vitamin A stores and intakes (geometric means: 352, 727, and 764 μg retinol activity equivalents/d for the Bangladeshi, Filipino, and Guatemalan children, respectively). Conclusions By collecting 1 or 2 blood samples from each child to generate a composite plasma tracer data set with a minimum of 5 children/time, group TBS and retinol kinetics can be estimated in children by compartmental analysis; inclusion of vitamin A intake data increases confidence in model predictions. The super-child modeling approach is an effective technique for comparing vitamin A status among children from different populations. These trials were registered at www.clinicaltrials.gov as NCT03000543 (Bangladesh), NCT03345147 (Guatemala), and NCT03030339 (Philippines).
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Green, Michael, Jennifer Ford, and Joanne Green. "Validation of a Method for Estimating Vitamin A Absorption Efficiency Based on Compartmental Analysis of Post-Prandial Plasma Retinyl Ester Kinetics." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 108. http://dx.doi.org/10.1093/cdn/nzaa041_012.

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Abstract Objectives Because good methods are not available to estimate vitamin A (VA) absorption, we evaluated an approach based on modeling retinyl ester response to an oral VA dose. Methods We generated data for 12 theoretical subjects, assigning values for VA absorption, stores, and kinetic parameters; we used WinSAAM (Simulation, Analysis and Modeling software) to simulate data (without and with 5% average error) for plasma chylomicron retinyl esters (RE) and retinol versus time (30 min to 8 h or 56 d, respectively) after ingestion of labeled VA; next we fit data to a previously-published 9-component model for VA metabolism to obtain “known” values for VA absorption. Then RE data only were modeled for each subject using a robust (n = 16 times) vs truncated sampling schedule (n = 10) and model-predicted absorptions were compared to known values. Areas under the plasma RE response curves (AUCs) were also calculated and compared to known absorption values. Results Known values for VA absorption based on modeling all data with error ranged from 54 – 92% (mean, 72%), VA stores from 160 – 1775 μmol, and chylomicron t1/2 from 6 – 12 min. Using the full sampling scheme for RE, the ratio of model-predicted to known absorption ranged from 0.927 – 1.06 (mean, 0.997); using the truncated scheme, the ratio was 0.814 – 1.13 (mean, 0.973). AUCs were not significantly correlated with known values for VA absorption (R2 = 0.112; P &gt; 0.05), presumably because absorption and chylomicron catabolism are occurring simultaneously. Conclusions By modeling chylomicron RE tracer data after ingestion of labeled VA, absorption efficiency was estimated accurately using error-free data; using data with 5% error, estimates were within 10% of known values (full sampling) or within 20% (truncated). If subjects, after an overnight fast, consume a breakfast containing some fat and a known amount of VA, then no tracer is required to estimate VA absorption using this modeling approach. By incorporating a population-based design, the method could be used in children. Funding Sources Supported by Bill & Melinda Gates Foundation (Project Number OPP1115464) and HarvestPlus (BH183438).
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Nolan, J. V., R. A. Leng, R. C. Dobos, and R. C. Boston. "The production of acetate, propionate and butyrate in the rumen of sheep: fitting models to 14C- or 13C-labelled tracer data to determine synthesis rates and interconversions." Animal Production Science 54, no. 12 (2014): 2082. http://dx.doi.org/10.1071/an14539.

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A procedure is described for solving an open, fully exchanging, three-compartment model representing ruminal volatile fatty acids (VFA) kinetics in sheep. This model was solved using results from a published study in which labelled VFA, viz. 1-14C-acetate (Ac), 1-14C-propionate (Pr) and 1-14C-butyrate (Bu), were infused individually at a constant rate for 240 min into the rumen of sheep on different occasions. During the tracer infusions, the sheep were given 75 g of lucerne (Medicago sativa) every hour. The patterns of increasing specific radioactivity (SA) during the infusions were described by differential equations that were solved using the computer software, WinSAAM. This linear kinetic analysis gave estimates of the rates of synthesis and absorption of Ac, Pr and Bu and the carbon interconversions between each acid. The sizes of the Ac, Pr and Bu compartments (10.5, 3.9 and 2.1 g C respectively), were also estimated, which is not possible with commonly used algebraic analyses. The model output showed that tracer : tracee equilibrium (plateau SA) had not been reached in the Ac, Pr and Bu compartments during the 240 min of tracer infusion and the algebraic method of analysis used in the original study was therefore compromised. The procedures described here eliminated this source of error; in addition, confidence in the model solution was improved because all data representing the build-up to plateau SA were used, rather than just estimates of ‘plateau’ SA. After accounting for VFA interconversions, the rates of VFA absorption (or incorporation into other materials such as microbial polymers or methane) were 85, 48 and 49 g C/day, or 78%, 91% and 73% of the total production of each VFA, respectively. The variability in the observed SA responses to the tracer infusions was relatively large and this is discussed. Model solutions using the linear kinetic analysis and the previously widely used algebraic analyses are compared. The effect of positional labelling in tracer VFA is also discussed in the light of evidence that the rate of absorption of Pr may be overestimated when [1-14C]-Pr rather than [2-14C]-Pr or uniformly labelled [14C]-Pr is used as the Pr tracer.
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Hodges, Joanna, Geoffrey Sasaki, and Richard Bruno. "Epigallocatechin Is Eliminated Faster From Plasma Than Epigallocatechin Gallate: Mathematical Modeling of Green Tea Catechin Metabolism in Healthy Adults." Current Developments in Nutrition 5, Supplement_2 (June 2021): 323. http://dx.doi.org/10.1093/cdn/nzab037_033.

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Abstract Objectives The predominant catechins [epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicatechin (EC), epicatechin gallate (ECG)] in green tea extract (GTE) vary in bioactivity. Our objective was to develop a physiologically relevant mathematical model of catechin metabolism and assess their fractional catabolic rates relative to their structural attributes, which may influence their bioactivities. Methods Pharmacokinetic data were collected from healthy adults (n = 18; 27 ± 7 y; 22 ± 2 kg/m2) after oral intake of 0.5 g GTE (EGCG: 290 mg, EGC: 87 mg, EC: 39 mg, ECG: 28 mg) delivered in 3 gelatin-based confections. Participants maintained a low-polyphenol diet for 3 d prior to the trial. Concentrations of deconjugated catechins were measured by LC-MS in plasma and urine collected at timed intervals over 12 and 24 h, respectively. A multi-compartment model of catechin metabolism was developed using the mean fraction of dose for all catechins. Data were fitted by iterative least squares regression analysis in WinSAAM software. Kinetic parameters for EGCG and EGC were compared using a Student t-test and one-way ANOVA. Results Observed data for each catechin were successfully fit into a 7-compartment model comprised of the gastrointestinal tract (stomach, small and large intestine), liver, plasma, extravascular tissues, and kidneys. Goodness of fit was ascertained by the estimated variability of parameters (FSD &lt; 0.5). Based on plasma response profiles, EGC and EC disappeared from plasma faster compared with EGCG and ECG. The highest fractional uptake was by the extravascular tissues (P &lt; 0.05) with no other between-organ differences. Compared with EGCG, EGC showed a higher fractional transfer from the liver to plasma (2.5 vs. 0.4 pools/h, P &lt; 0.001) and the uptake by kidneys (1.2 vs. 0.01 pools/h, P &lt; 0.001) with no difference in absorption. The fractional catabolic rate was also higher for EGC compared with EGCG (59.4 vs. 42.7 plasma pools/h, P &lt; 0.05), while its plasma transit time was shorter (0.9 vs. 1.3 min, P &lt; 0.05). Conclusions A 7-compartment model, to be validated in a future study, was successfully developed to demonstrate that EGC is eliminated faster compared with EGCG in healthy adults, suggesting that the gallate group may influence relative bioactivity of catechins. Funding Sources The Ohio State University and the National Institute of Food and Agriculture.
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Smith, Scott M., and David B. Whitlark. "WINSTAT 2.0 [Computer Software]." Journal of Marketing Research 31, no. 1 (February 1994): 141. http://dx.doi.org/10.2307/3151956.

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Divall, Colin. "(Alan) Winstan Bond, OBE." Journal of Transport History 30, no. 1 (June 2009): v—vii. http://dx.doi.org/10.7227/tjth.30.1.2.

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Dissertations / Theses on the topic "Winsaam"

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Herron, Fiona Michelle. "A study of digesta passage in rabbits and ringtail possums using markers and models." Thesis, The University of Sydney, 2002. http://hdl.handle.net/2123/483.

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The common ringtail possum (Pseudocheirus peregrinus), a member of the family Pseudocheiridae, is an arboreal folivorous marsupial that feeds predominantly on Eucalyptus foliage. Contrary to the expectation that small body size would inhibit utilisation of a diet containing such high levels of lignified fibre because of relatively low gut volume to body mass ratios and relatively high mass-specific metabolic rates and nutrient requirements (Hume 1999), the ringtail possum is able to survive solely on a diet of Eucalyptus foliage. The rabbit (Oryctolagus cuniculus) is a terrestrial herbivore and is a member of the family Leporidae that feeds predominantly on grasses. The rabbit was proposed as a digesta flow model for the ringtail possum since both are caecotrophic (periodically re-ingest caecal contents) and both are proposed to exhibit a colonic separation mechanism (CSM) where fluids and small, easily digested particles are preferentially returned to the caecum. The rabbit is of value for the modelling process since it is more accessible for experimental manipulation than the ringtail possum. This study investigated a proposal to use digesta passage through the gastrointestinal tract (GIT) of the rabbit as a model of digesta passage for the ringtail possum on the basis that both are caecotrophic caecum fermenters. A number of potential problems were identified with this proposal and investigation of these problems formed the basis for the research described in this thesis. Two main areas were identified as being potentially problematic: 1) fundamental flaws with the particulate markers used in digesta rate of passage studies; and 2) differences in animal behaviour and natural diet between the two subject species which suggested different digestive strategies and hence different patterns of digesta flow through the GIT. The proposed digesta passage markers were lanthanide metals (Dy, Tm, Eu and Yb) attached to either fibrous particles (1200 - 600�m) or formalin-fixed rumen bacteria (20 � 0.2�m). These markers were shown to not be of the assumed size classes and the extent of lanthanide metal binding differed between the four metals used. An effect due to method of dosing was also observed. The findings of marker inconsistencies caused major limitation to model development and further research is necessary to clarify these markers. The proposal to use digesta flow in the rabbit GIT as a model for digesta flow in the ringtail possum was shown to be idealistic due to the differences in anatomy and behaviour observed between the two herbivores. Laboratory observations, time series analysis and compartmental modelling confirmed the differences between the animals. This study showed: 1) the GIT of the rabbit was more complex both anatomically and functionally than that of the ringtail possum; 2) behaviour affecting digesta passage of the rabbit and ringtail were different and; 3) compartmental models confirmed the anatomical and behavioural findings. Digesta passage in the rabbit could not be modelled mathematically using data on digesta passage due to complexities of the system. In contrast, a basic model was constructed for digesta passage in the ringtail possum. On the basis of these findings, the research hypothesis "that digesta passage in rabbits is similar to that in ringtail possums" was rejected.
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Herron, Fiona Michelle. "A study of digesta passage in rabbits and ringtail possums using markers and models." University of Sydney. Biology, 2002. http://hdl.handle.net/2123/483.

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The common ringtail possum (Pseudocheirus peregrinus), a member of the family Pseudocheiridae, is an arboreal folivorous marsupial that feeds predominantly on Eucalyptus foliage. Contrary to the expectation that small body size would inhibit utilisation of a diet containing such high levels of lignified fibre because of relatively low gut volume to body mass ratios and relatively high mass-specific metabolic rates and nutrient requirements (Hume 1999), the ringtail possum is able to survive solely on a diet of Eucalyptus foliage. The rabbit (Oryctolagus cuniculus) is a terrestrial herbivore and is a member of the family Leporidae that feeds predominantly on grasses. The rabbit was proposed as a digesta flow model for the ringtail possum since both are caecotrophic (periodically re-ingest caecal contents) and both are proposed to exhibit a colonic separation mechanism (CSM) where fluids and small, easily digested particles are preferentially returned to the caecum. The rabbit is of value for the modelling process since it is more accessible for experimental manipulation than the ringtail possum. This study investigated a proposal to use digesta passage through the gastrointestinal tract (GIT) of the rabbit as a model of digesta passage for the ringtail possum on the basis that both are caecotrophic caecum fermenters. A number of potential problems were identified with this proposal and investigation of these problems formed the basis for the research described in this thesis. Two main areas were identified as being potentially problematic: 1) fundamental flaws with the particulate markers used in digesta rate of passage studies; and 2) differences in animal behaviour and natural diet between the two subject species which suggested different digestive strategies and hence different patterns of digesta flow through the GIT. The proposed digesta passage markers were lanthanide metals (Dy, Tm, Eu and Yb) attached to either fibrous particles (1200 - 600�m) or formalin-fixed rumen bacteria (20 � 0.2�m). These markers were shown to not be of the assumed size classes and the extent of lanthanide metal binding differed between the four metals used. An effect due to method of dosing was also observed. The findings of marker inconsistencies caused major limitation to model development and further research is necessary to clarify these markers. The proposal to use digesta flow in the rabbit GIT as a model for digesta flow in the ringtail possum was shown to be idealistic due to the differences in anatomy and behaviour observed between the two herbivores. Laboratory observations, time series analysis and compartmental modelling confirmed the differences between the animals. This study showed: 1) the GIT of the rabbit was more complex both anatomically and functionally than that of the ringtail possum; 2) behaviour affecting digesta passage of the rabbit and ringtail were different and; 3) compartmental models confirmed the anatomical and behavioural findings. Digesta passage in the rabbit could not be modelled mathematically using data on digesta passage due to complexities of the system. In contrast, a basic model was constructed for digesta passage in the ringtail possum. On the basis of these findings, the research hypothesis "that digesta passage in rabbits is similar to that in ringtail possums" was rejected.
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Fernández, Velásquez Rosa A. "Application of WinSLAMM to Evaluate the Effect of Green Infrastructure Implementation in Northern Utah." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7405.

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This study provides an evaluation of the performance of the WinSLAMM model in two cities of northern Utah, a region in which it has not been validated to date. Runoff volumes for a series of events from 2015 to 2017 were calculated for six study areas. These results were compared to model outputs to evaluate the prediction accuracy. The model performed poorly when default parameters where used, as expected. Thus, the calibration of runoff coefficient was done with local data. Total suspended solids (TSS), total phosphorus (TP) and total dissolved phosphorus (TDP) were also evaluated and calibrations were developed. The WinSLAMM model performed well for TSS prediction and TP and TDP estimations were calculated with the TP/TSS and TDP/TP ratios observed in the data for the Logan study areas. Three scenarios of GI implementation were analyzed; the treatment of 10%, 50% and 100% of connected impervious surfaces. For the 10% case, treating streets produced the greatest TSS reduction, while treating roofs yielded the greatest volume reduction. For the 50% case, there was a great difference in TSS reduction with varying surfaces. Implementing GI for streets produced the largest TSS reduction, followed by parking lots and then by roofs.
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Pinto, Viviane Machado. "Avaliação toxicológica da preparação fitoterápica contendo Piper methysticum Forst, piperaceae (Kava Kava ) sobre o desenvolvimento pré-natal de ratos winstar." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2004. http://hdl.handle.net/10183/6756.

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A kava kava (Piper methysticum Forst), pertencente à família Piperaceae, é utilizada para diminuir a ansiedade e medo e tratar distúrbios comportamentais. É um fitoterápico utilizado em vários países, entretanto pouco se sabe, sobre seus efeitos no desenvolvimento embrionário. O presente trabalho avaliou o possível efeito teratogênico da formulação fitoterápica contendo Piper methysticum Forst durante o período de organogênese em ratas Wistar. As ratas foram tratadas com 0mg.kg –1 (controle), 5mg.kg –1 ; 35mg.kg –1 e 50mg.kg –1 da preparação fitoterápica (kava kava®), por via oral, do 6° ao 15° dia de prenhez. Os resultados revelaram ausência de toxicidade sistêmica e reprodutiva nas variáveis avaliadas, fundamentados pela ausência de alterações no desenvolvimento ponderal, consumos de ração e água, na massa relativa dos órgãos, nas reabsorções embrionárias, na massa corporal, na vitalidade, no número de fetos por progenitora e nas alterações macroscópicas externas e esqueléticas dos fetos. Adicionalmente as enzimas alanina aminotrasferase (ALT) e fosfatase alcalina (FA) foram determinadas no soro das ratas tratadas, para avaliar o possível efeito hepatotóxico da preparação fitoterápica. Não houve alteração na atividade das enzimas ALT e FA, bem como alterações histopatológicas do fígado das ratas, não confirmando a hepatotoxicidade. Conclui-se que o fitoterápico kava kava, até 35mg.kg –1, não determina o aparecimento de teratogenicidade.
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Nazari, Saeid. "ASSESSMENT OF WATERSHED NUTRIENT LOADS AND EFFECTIVENESS OF BEST MANAGEMENT PRACTICES." UKnowledge, 2018. https://uknowledge.uky.edu/ce_etds/63.

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Several methods have been developed for use in estimating the water quality loads associated with urban and agricultural landuses and practices. These include the use of sophisticated computer models, typically based on using pollutant loading and runoff functions, regression equations, load export coefficients (LECs), and event mean concentrations (EMCs). This research has examined the feasibility of using a simple EMC approach with the Kentucky Nutrient Model (KYNM). The thesis includes an extensive literature review of EMCs and a synthesis of recommended values for a range of typical urban and agricultural landuses. The thesis also includes an extensive literature review of potential BMPs along with a summary of the typical removal efficiencies and costs associated with each type of BMP. The research also explored the potential to use the results from multiple applications of site specific BMP models like the Source Loading and Management Model (WinSLAMM) in the development of general functional relationships that could then be used to evaluate BMP performance on a more site-specific basis. The developed EMC table and the associated BMP performance curves should provide valuable tools for use in better managing nutrient loads for urban and agricultural watersheds.
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Lundell, Johan, and Gustav Sjögren. "Användarcentrerad utveckling av mobilt IT-stöd." Thesis, Jönköping University, JTH, Computer and Electrical Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-386.

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This exam paper has been a collaboration between the writers and SYSteam Utvecklingspartner in Huskvarna. The assignment was about finding a need for a mobile application, making a requirement specification document with design documents and parallel to this constructing a prototype. The assignment is summarized in the following questions:

• How can companies in the forest industry benefit from mobile information technology?

• How can a user centered perspective be used in the process of making the requirement specification document and the design documents?

• How do guidelines for usability apply to a mobile application?

Three visits to companies in the forest industry were made to find a need for mobile information technology solutions. After a small analysis of the different companies’ problems and conditions the decision was to use Tenhults Impregneringsverk AB in the case study.

We used the FA/SIM method in our job of finding the organization needs for change and the principles of User Centered Design in the work of constructing a prototype.

The result of our work is a requirement specification with design documents and a prototype. The final prototype is an application deployed on to a PDA with a barcode scanner.

Our conclusion is that the purpose of mobile information technology often is about making the torrent of information more effective by reducing the duplication of work and securing the quality of the information.

Using a user centered perspective in the development work has in general terms worked out pretty well for us. Requirements and demands of the application have become clearer to us after each iteration, and in the end the customer and the developer organization where on the same terms.

We have been able to apply the guidelines of usability on MobSaw (is the name of the application prototype that was made during the exam work). The principles are universal; the biggest difference is about input and screen size because the hardware’s capacity is limited. The advantages of the smaller frameworks for mobile devices is that the focus on usability increases.

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WANG, YU-AN, and 王雨安. "Application of Lean Method on Forging Process in Hand Tool Factory – A Case Study of WINSAM Company." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/e8975h.

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碩士
修平科技大學
精實生產管理碩士班
105
For a traditional metal processing industry, the number of defective products needed to be reduced, while the efficiency of the hand tool manufacturing process had to be enhanced. This study, aimed to reduce the defect rate by applying the Taguchi method in a hand tool factory, investigated whether the defect rate could be reduced by adjusting the forging process to reduce unnecessary costs. To this end, five techniques in a lean method were employed to determine the value, define the value process, smooth the process, establish a pull production system, and perfect and improve the factory environment and process. Based on the five techniques, we further resorted to a method where a Taguchi orthogonal table was used to find the signal-to-noise (S/N) ratio, and thus to identify the control factors, influencing factors, quality characteristics, parameter design, and defect rate, through which the optimal parameter combination was determined. In this study, A1-B1-C2-D2, which achieved the lowest S/N ratio, constituted the optimal combination, where the process control factors of forging temperature (A1), transfer speed (B1), and the number of cavities per mold were adjusted to 1100℃, 3 seconds, and 4, respectively, and the material of Chrome vanadium steel (40CRV) was employed. This combination could reduce the defect rate a little bit, and enhance the process efficiency.
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Books on the topic "Winsaam"

1

Coe, Jonathan. La famiglia Winshaw. Milano: Feltrini, 1996.

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Coe, Jonathan. The Winshaw legacy: Or, what a carve up! New York: Knopf, 1995.

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The Winshaw Legacy. Random House Value Publishing, 1996.

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Coe, Jonathan. La Famiglia Winshaw (Universale Economica). Feltrinelli, 2000.

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Legado da Família Winshaw, O. Record, 2002.

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Butts, Derrick, and Shaundale Rena. Make Every Day a Winsday. Independently Published, 2019.

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The Winshaw Legacy: Or, What a Carve Up! Vintage, 1996.

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Ltd, ICON Group, and ICON Group International Inc. WINSTAR COMMUNICATIONS, INC.: Labor Productivity Benchmarks and International Gap Analysis (Labor Productivity Series). 2nd ed. Icon Group International, 2000.

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Ltd, ICON Group. WINSTAR COMMUNICATIONS, INC.: International Competitive Benchmarks and Financial Gap Analysis (Financial Performance Series). 2nd ed. Icon Group International, 2000.

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Book chapters on the topic "Winsaam"

1

Novotny, Janet A., Peter Greif, and Raymond C. Boston. "WinSAAM: Application and Explanation of Use." In Advances in Experimental Medicine and Biology, 343–51. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9019-8_22.

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Greif, Peter, Meryl Wastney, Oscar Linares, and Ray C. Boston. "Balancing Needs, Efficiency, and Functionality in the Provision of Modeling Software: A Perspective of the NIH WinSAAM Project." In Advances in Experimental Medicine and Biology, 3–20. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-1959-5_1.

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Rogers, Kathleen Béres. "Jane Cave Winscom (1752–1812)." In The Routledge Companion to Romantic Women Writers, 172–76. London: Routledge, 2022. http://dx.doi.org/10.4324/9781315613536-20.

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Kostin, Alexander, and Ljudmila Ilushechkina. "Winsim: A Tool for Performance Evaluation of Parallel and Distributed Systems." In Advances in Information Systems, 312–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-30198-1_32.

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Wastney, Meryl E., Blossom H. Patterson, Oscar A. Linares, Peter C. Greif, and Ray C. Boston. "WinSAAM." In Investigating Biological Systems Using Modeling, 95–138. Elsevier, 1999. http://dx.doi.org/10.1016/b978-0-08-092645-2.50010-9.

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Carter, I. C., J. R. Claydon, and M. J. Hill. "Improving the watertightness of Winscar Reservoir." In Reservoirs in a Changing World, 415–30. Thomas Telford Publishing, 2002. http://dx.doi.org/10.1680/riacw.31395.0033.

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Wilson, A. C., and A. C. Robertshaw. "Winscar Dam: Investigations and repairs to asphaltic concrete membrane." In The prospect for reservoirs in the 21st century, 292–302. Thomas Telford Publishing, 1998. http://dx.doi.org/10.1680/tpfrit21c.27046.0025.

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"WinSAAM Dictionary**See also Fig 6.1 and Tables 6.3 and 6.4. I implies a compartment, n is not associated with a compartment. Only the first four letters of a command need to be entered, as indicated by capitals (e.g., ITER is the command for iterate)." In Investigating Biological Systems Using Modeling, 367–70. Elsevier, 1999. http://dx.doi.org/10.1016/b978-0-08-092645-2.50028-6.

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Kovacevic, N., P. Vaughan, and D. Potts. "A comparison between observed and predicted deformations of Winscar dam." In Numerical Models in Geomechanics, 565–71. Taylor & Francis, 2002. http://dx.doi.org/10.1201/9781439833797-c84.

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Kostin, Alexander. "Extremely Fast Heuristic Event-Driven Job Shop Scheduler With a New Class of Extended Petri Nets." In Advances in Marketing, Customer Relationship Management, and E-Services, 512–39. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-5077-9.ch025.

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Abstract:
A very fast scheduling system is proposed and experimentally investigated. The system consists of a job shop manager and dynamic models of machines. A schedule is created in the course of a close cooperation with models of the machines that generate driving events for the scheduler. The system is implemented with a new class of extended Petri nets and runs in the environment of the Petri-net tool WINSIM. The scheduler creates a schedule sequentially, without any form of enumerative search. To investigate the scheduler performance, a large number of experiments were conducted with the use of few strategies. Due to a unique mechanism of monitoring of triggering events in the Petri net, the developed scheduler runs at least hundreds of times faster than any known single-processor job shop scheduler.
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Conference papers on the topic "Winsaam"

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Pitt, Robert, Leila Talebi, Deborah O'Bannon, Dustin Bambic, Jason Wright, and Michelle Simon. "Comparison of WinSLAMM Modeled Results with Monitored Bioinfiltration Data during Kansas City Green Infrastructure Demonstration Project." In World Environmental and Water Resources Congress 2013. Reston, VA: American Society of Civil Engineers, 2013. http://dx.doi.org/10.1061/9780784412947.290.

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Kabbes, Karen C., Stephen McCracken, and John W. Hood. "Determining Cost Effective Pollution Reduction BMP Scenarios for Low Impact Redevelopment and a Watershed Plan Using WinSLAMM." In International Low Impact Development Conference 2008. Reston, VA: American Society of Civil Engineers, 2008. http://dx.doi.org/10.1061/41009(333)57.

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