Dissertations / Theses on the topic 'WINNER II'

This project aimed to classified artificiality gener-ated,fake, and authentic,true, telecommunication signals, basedupon their frequency response, using methods from deep learn-ing. Another goal was to accomplish this with the least amountof dimension of data possible. The datasets used contained of anequal amount of measured, provided by Ericsson, and generated,by a WINNER II implementation in Matlab, frequency responses.It was determined that a normalized version of the absolute valueof the complex frequency response was enough information for afeedforward network to do a sufficient classification. To improvethe accuracy of the network we did a hyperparameter search,which allowed us to reach an accuracy of 90 percent on our testdataset. The results show that it is possible for neural networksto differentiate between true and fake telecommunication signalsbased on their frequency response, even if it is hard for a humanto tell the difference.<br>Målet med det här projektet var att klassificera artificiellt genererade signaler, falska, och riktiga, sanna, telekommunikation signaler med hjälp av signalernas frekvens- svar med djup inlärningsmetoder, deep learning. Ett annat mål med projektet var att klassificera signalerna med minsta möjliga antalet dimensioner av datan. Datasetet som användes bestod av till hälften av uppmät data som Ericsson har tillhandahållit, och till hälften av generad data ifrån en WINNER II modell implementerad i Matlab. En slutsats som kunde dras är att en normaliserad version av beloppet av det komplexa frekvenssvaret innehöll tillräckligt med information för att träna ett feedforward nätverk till att uppnå en hög klassificeringssäkerhet. För att vidare öka tillförlitligheten av nätverket gjordes en hyperparametersökning, detta ökade tillförligheten till 90 procent för testdataseten. Resultaten visar att det är möjligt för neurala nätverk att skilja mellan sanna och falska telekommunikations- signaler baserat på deras frekvenssvar, även om det är svårt för människor att skilja signalerna åt.<br>Kandidatexjobb i elektroteknik 2020, KTH, Stockholm

This thesis first presents a least squares regression model to identify the in-game statistics that help explain the variation in point spread for NCAA Division II Women’s Basketball Tournament games. Then a logistic regression model is presented to estimate the probability of a team winning a tournament game based on the differences in significant in-game statistics. Differences in the following variables are significant in both models: field goal percentage, 3-point field goal percentage, free throw percentage, offensive rebounds, personal fouls and turnovers. Difference in assists is only significant in the point spread model. Both models are validated using the in-game statistics for the 2015 tournament, indicating a prediction accuracy as high as 95.24%. Seasonal averages for the 2014 - 2015 season are then used to predict game results in the 2015 tournament. The prediction accuracies are 60.32% and 66.67% for the point spread model and the logistic regression model, respectively.

Made available in DSpace on 2014-12-17T15:42:28Z (GMT). No. of bitstreams: 1 MonicaRO_TESE.pdf: 4155777 bytes, checksum: 6bff63b5cb0f37e64dfe6fcb144dae79 (MD5) Previous issue date: 2014-01-23<br>The environmental impact due to the improper disposal of metal-bearing industrial effluents imposes the need of wastewater treatment, since heavy metals are nonbiodegradable and hazardous substances that may cause undesirable effects to humans and the environment. The use of microemulsion systems for the extraction of metal ions from wastewaters is effective when it occurs in a Winsor II (WII) domain, where a microemulsion phase is in equilibrium with an aqueous phase in excess. However, the microemulsion phase formed in this system has a higher amount of active matter when compared to a WIII system (microemulsion in equilibrium with aqueous and oil phases both in excess). This was the reason to develop a comparative study to evaluate the efficiency of two-phases and three-phases microemulsion systems (WII and WIII) in the extraction of Cu+2 and Ni+2 from aqueous solutions. The systems were composed by: saponified coconut oil (SCO) as surfactant, n-Butanol as cosurfactant, kerosene as oil phase, and synthetic solutions of CuSO4.5H2O and NiSO4.6H2O, with 2 wt.% NaCl, as aqueous phase. Pseudoternary phase diagrams were obtained and the systems were characterized by using surface tension measurements, particle size determination and scanning electron microscopy (SEM). The concentrations of metal ions before and after extraction were determined by atomic absorption spectrometry. The extraction study of Cu+2 and Ni+2 in the WIII domain contributed to a better understanding of microemulsion extraction, elucidating the various behaviors presented in the literature for these systems. Furthermore, since WIII systems presented high extraction efficiencies, similar to the ones presented by Winsor II systems, they represented an economic and technological advantage in heavy metal extraction due to a small amount of surfactant and cosurfactant used in the process and also due to the formation of a reduced volume of aqueous phase, with high concentration of metal. Considering the reextraction process, it was observed that WIII system is more effective because it is performed in the oil phase, unlike reextraction in WII, which is performed in the aqueous phase. The presence of the metalsurfactant complex in the oil phase makes possible to regenerate only the surfactant present in the organic phase, and not all the surfactant in the process, as in WII system. This fact allows the reuse of the microemulsion phase in a new extraction process, reducing the costs with surfactant regeneration<br>O impacto ambiental gerado pelo descarte de efluentes industriais carregados de metais pesados imp?e a necessidade do tratamento desses rejeitos, uma vez que s?o t?xicos e n?o biodegrad?veis, podendo causar s?rios danos ? popula??o e ao meio ambiente. O processo de extra??o de c?tions met?licos utilizando microemuls?es ? eficaz quando acontece em WII, onde a fase microemulsionada encontra-se em equil?brio com uma fase aquosa em excesso. No entanto, a microemuls?o formada nesse sistema possui uma maior quantidade de mat?ria ativa quando comparada ao equil?brio de WIII (microemuls?o em equil?brio com fases aquosa e oleosa, ambas em excesso), ainda pouco estudado, motivando, assim, o desenvolvimento de um estudo comparativo da efici?ncia de extra??o dos ?ons Cu2+ e Ni2+ por sistemas microemulsionados bif?sicos e trif?sicos (WII e WIII). Os constituintes utilizados nos sistemas de extra??o foram: ?leo de coco saponificado - OCS (Tensoativo), n- Butanol (Cotensoativo), querosene (Fase Oleosa) e solu??es sint?ticas de CuSO4.5H2O e NiSO4.6H2O com NaCl 2% (fases aquosas). Foram obtidos os diagramas de fases pseudotern?rios e os sistemas microemulsionados foram caracterizados atrav?s das t?cnicas de tens?o superficial, tamanho de part?culas e microscopia eletr?nica de varredura (MEV). A concentra??o dos ?ons foi determinada por espectrometria de absor??o at?mica. O estudo da extra??o dos c?tions met?licos Cu2+ e Ni2+ na regi?o de WIII contribuiu para um melhor entendimento dos processos de extra??o por microemuls?o, elucidando os v?rios comportamentos apresentados na literatura para esses sistemas. Al?m disso, uma vez que houve uma alta efici?ncia de extra??o, similar aos sistemas de Winsor II, o sistema trif?sico (WIII), por apresentar uma menor quantidade de tensoativo e cotensoativo, e um menor volume de fase aquosa ap?s a extra??o, levou a uma maior concentra??o do metal, representando uma vantagem econ?mica e tecnol?gica do processo. Assim, a extra??o em sistema trif?sico ? vi?vel e, apesar dos percentuais de extra??o em WII e WIII serem semelhantes, o sistema de WIII leva a uma maior concentra??o do metal na fase extrato. O presente trabalho mostrou, ainda, que a etapa de reextra??o para os sistemas em WIII ? mais eficaz pois, diferentemente da extra??o em Winsor II, ela ? realizada na fase oleosa, onde est? depositado o complexo metal/tensoativo, regenerando somente o tensoativo que complexa com o metal na fase org?nica, e n?o todo o tensoativo utilizado, como ? o caso do equil?brio em Winsor II. Este fato viabiliza a reutiliza??o da fase microemuls?o no processo de extra??o, diminuindo os custos de regenera??o do tensoativo

Rezensiertes Werk: Rehse, Birgit: Die Supplikations- und Gnadenpraxis in Brandenburg-Preußen : eine Untersuchung am Beispiel der Kurmark unter Friedrich Wilhelm II. (1786 - 1797) / von Birgit Rehse. - Berlin : Duncker & Humblot, c 2008. - 676 S. : Ill. - (Quellen und Forschungen zur brandenburgischen und preußischen Geschichte ; 35) Zugl.: Berlin, Freie Univ., Diss., 2006 ISBN-10 3-428-12591-6 <A href='www.pickitisbn:3-428-12591-6'><img style='border: 0px none' src='https://www.citavi.com/softlink?linkid=findit' title='Titel anhand dieser ISBN in Citavi-Projekt übernehmen'/></A> ISBN-13 978-3-428-12591-3 <A href='www.pickitisbn:978-3-428-12591-3'><img style='border: 0px none' src='https://www.citavi.com/softlink?linkid=findit' title='Titel anhand dieser ISBN in Citavi-Projekt übernehmen'/></A>

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-02-01T21:27:07Z No. of bitstreams: 1 EmilyCintiaTossiDeAraujoCosta_TESE.pdf: 2216846 bytes, checksum: 5f38e382d8ae3c1bfe9f3db58b62a672 (MD5)<br>Approved for entry into archive by Elisangela Moura (lilaalves@gmail.com) on 2016-02-02T21:24:40Z (GMT) No. of bitstreams: 1 EmilyCintiaTossiDeAraujoCosta_TESE.pdf: 2216846 bytes, checksum: 5f38e382d8ae3c1bfe9f3db58b62a672 (MD5)<br>Made available in DSpace on 2016-02-02T21:24:40Z (GMT). No. of bitstreams: 1 EmilyCintiaTossiDeAraujoCosta_TESE.pdf: 2216846 bytes, checksum: 5f38e382d8ae3c1bfe9f3db58b62a672 (MD5) Previous issue date: 2013-09-23<br>A contamina??o de ?guas naturais por metais tornou-se assunto de interesse p?blico mundial por serem considerados biocumulativos. A determina??o e o monitoramento de contaminantes met?licos em ?guas ? uma tarefa que deve ser cont?nua e por isto a import?ncia do desenvolvimento, modifica??o e otimiza??o de metodologias anal?ticas capazes de realizar a determina??o dos v?rios contaminantes met?licos em ambientes naturais, pois em muitos casos, a instrumenta??o dispon?vel n?o apresenta sensibilidade anal?tica suficiente para a determina??o de tra?os. Neste estudo, um m?todo de extra??o e pr?-concentra??o utilizando um sistema microemulsionado, no equil?brio de Winsor II foi testado e otimizado para a determina??o dos metais Co, Cd, Pb, Tl, Cu e Ni por Espectrometria de absor??o at?mica de alta resolu??o com fonte cont?nua e atomiza??o em forno de grafite e chama (HR-CS AAS). A otimiza??o do programa de temperatura para o forno de grafite foi realizada atrav?s de curvas de pir?lise e atomiza??o para cada analito sem e com o uso de diferentes modificadores qu?micos. Cd e Pb tiveram condi??es ?timas com modificador permanente Ru, pir?lise em 700?C e atomiza??o em 1700?C, para Tl solu??o Pd/Mg foi o melhor modificador, temperaturas 600?C e 1700?C de pir?lise e atomiza??o, respectivamente e para o Co pir?lise em 800?C e atomiza??o ? 2400?C sem uso de modificador qu?mico, por?m W foi empregado como modificador permanente a fim de se prolongar o tempo de vida ?til do forno. Cu e Ni foram analisados na chama ap?s pr?-concentra??o. Avaliou-se tamb?m fatores que influenciam a efici?ncia de extra??o, atrav?s do efeito salting out. Como compromisso, 6 g L-1 de Na e 1% de HNO3 (v/v) foi definido. Para determina??o do ponto ?timo de extra??o, um planejamento centroide-simplex foi aplicado, sendo escolhido como compromisso as seguintes propor??es: 70% fase aquosa, 10% fase ?leo e 20% Cotensoativo/Tensoativo (C/T = 4). Ap?s extra??o, os metais foram determinados e as Figuras de m?rito obtidas para o m?todo proposto foi: 0,1 a 10 ?g L-1 de faixa linear, LOD 0,094, 0,011, 0,057 e 0,050 ?g L-1 para Pb, Cd, Tl e Co, respectivamente. Testes de adi??o e recupera??o na amostra certificada apresentaram valores de recupera??o ap?s extra??o de 105 e 101% para Pb e Cd, respectivamente, e nas amostras fortificadas a recupera??o para os analitos ficou entre 107 e 108% comprovando que o m?todo proposto pode ser utilizado na extra??o, possibilitou a separa??o dos metais de matrizes complexas, e ainda com bom fator de pr?-concentra??o.<br>The determination and monitoring of metallic contaminants in water is a task that must be continuous, leading to the importance of the development, modification and optimization of analytical methodologies capab le of determining the various metal contaminants in natural environments, because, in many cases, the ava ilable instrumentation does not provide enough sensibility for the determination of trace values . In this study, a method of extraction and pre- concentration using a microemulsion system with in the Winsor II equilibrium was tested and optimized for the determination of Co, Cd, P b, Tl, Cu and Ni through the technique of high- resolution atomic absorption spectrometry using a continuum source (HR-CS AAS). The optimization of the temperature program for the graphite furnace (HR-CS AAS GF) was performed through the pyrolysis and atomization curves for the analytes Cd, Pb, Co and Tl with and without the use of different chemical modifiers. Cu and Ni we re analyzed by flame atomization (HR-CS F AAS) after pre-concentr ation, having the sample introduction system optimized for the realization of discrete sampling. Salinity and pH levels were also analyzed as influencing factors in the efficiency of the extraction. As final numbers, 6 g L -1 of Na (as NaCl) and 1% of HNO 3 (v/v) were defined. For the determination of the optimum extraction point, a centroid-simplex statistical plan was a pplied, having chosen as the optimum points of extraction for all of the analytes, the follo wing proportions: 70% aqueous phase, 10% oil phase and 20% co-surfactant/surfactant (C/S = 4). After extraction, the metals were determined and the merit figures obtained for the proposed method were: LOD 0,09, 0,01, 0,06, 0,05, 0,6 and 1,5 ?g L -1 for Pb, Cd, Tl, Co, Cu and Ni, re spectively. Line ar ranges of ,1- 2,0 ?g L -1 for Pb, 0,01-2,0 ?g L -1 for Cd, 1,0 - 20 ?g L -1 for Tl, 0,1-5,0 ?g L -1 for Co, 2-200 ?g L -1 and for Cu e Ni 5-200 ?g L -1 were obtained. The enrichment factors obtained ranged between 6 and 19. Recovery testing with the certified sample show ed recovery values (n = 3, certified values) after extraction of 105 and 101, 100 and 104% for Pb, Cd, Cu and Ni respectively. Samples of sweet waters of lake Jiqui, saline water from Potengi river and water produced from the oil industry (PETROBRAS) were spiked and the recovery (n = 3) for the analytes were between 80 and 112% confirming th at the proposed method can be used in the extraction. The proposed method enabled the sepa ration of metals from complex matrices, and with good pre-concentration factor, consistent with the MPV (allowed limits) compared to CONAMA Resolution No. 357/2005 which regulat es the quality of fresh surface water, brackish and saline water in Brazil.

In this study, we explore models for optimal bidding in auctions on the bond market using data gathered from the Bloomberg Fixed Income Trading platform and MIFID II reporting. We define models that aim to fulfill two purposes. The first is to hit the best competitor price, such that a dealer can win the trade with the lowest possible margin. This model should also take into account the phenomenon of the Winner's Curse, which states that the winner of a common value auction tends to be the bidder who overestimated the value. We want to avoid this since setting a too aggressive bid could be unprofitable even when the dealer wins. The second aim is to define a model that estimates a quote that allows the dealer to win a certain target ratio of trades. We define three novel models for these purposes that are based on the best competitor prices for each trade, modeled by a Skew Exponential Power distribution. Further, we define a proxy for the Winner's Curse, represented by the distance of the estimated price from a reference price for the trade calculated by Bloomberg which is available when the request for quote (RFQ) arrives. Relevant covariates for the trades are also included in the models to increase the specificity for each trade. The novel models are compared to a linear regression and a random forest regression method using the same covariates. When trying to hit the best competitor price, the regression models have approximately equal performance to the expected price method defined in the study. However, when incorporating the Winner's Curse proxy, our Winner's Curse adjusted models are able to reduce the effect of the Winner's Curse as we define it, which the regression methods cannot. The results of the models for hitting a target ratio show that the actual hit ratio falls within an interval of 5% of the desired target ratio when running the model on the test data. The inclusion of covariates in the models does not impact the results as much as expected, but still provide improvements with respect to some measures. In summary, the novel methods show promise as a first step towards building algorithmic trading for bonds, but more research is needed and should incorporate more of the growing data set of RFQs and MIFID II recorded transaction prices.<br>I denna studie utforskar vi modeller för optimal budgivning för auktioner på obligationsmarknaden med hjälp av data som samlats in från plattformen Bloomberg Fixed Income Trading och MIFID II-rapportering. Vi definierar modeller som ämnar att uppfylla två syften. Det första är att träffa det bästa konkurrentpriset så att en handlare kan vinna auktionen med minsta möjliga marginal. Denna modell bör också ta hänsyn till fenomenet Winner's Curse, som innebär att vinnaren av en så kallad common value auction tenderar att vara den budgivare som överskattat värdet. Vi vill undvika detta eftersom det kan vara olönsamt att skicka ett alltför aggressivt bud även om handlaren vinner. Det andra syftet är att definiera en modell som uppskattar ett pris som gör det möjligt för handlaren att vinna en viss andel av sina obligationsaffärer. Vi definierar tre nya modeller för dessa ändamål som bygger på de bästa konkurrentpriserna för varje transaktion vi har data på. Dessa modelleras av en Skew Exponential Power-fördelning. Vidare definierar vi en variabel som indirekt mäter fenomenet Winner's Curse, representerad av budprisets avstånd från ett referenspris för transaktionen beräknad av Bloomberg som är tillgänglig när en request for quote (RFQ) anländer. Relevanta kovariat för transaktionen implementeras också i modellerna för att öka specificiteten för varje transaktion. De nya modellerna jämförs med en linjärregression och en random forest-regression som använder samma kovariat. När målet är att träffa det bästa konkurrentpriset ger regressionsmodellerna ungefär samma resultat som expected price-modellen som definieras i denna studie. När man däremot integrerar effekten av Winner's Curse med den definierade indirekta variablen kan vår Winner's Curse-justerade modell minska effekten av Winner's Curse, vilket regressionsmetoderna inte kan. Resultaten av modellerna som ämnar vinna en förbestämd andel av transaktionerna visar att den faktiska andelen transaktioner som man vinner faller inom ett intervall på 5% kring den önskade andelen när modellen körs på testdata. Att inkludera kovariat i modellerna påverkar inte resultaten till den grad som uppskattades, men ger mindre förbättringar med avseende på vissa mättal. Sammanfattningsvis visar de nya metoderna potential som ett första steg mot att bygga algoritmisk handel för obligationer, men mer forskning behövs och bör utnyttja mer av den växande datamängden av RFQs och MIFID II-rapporterade transaktionspriser.

Tandis que la Drôle de Guerre est l’occasion d’une première confrontation avec la réglementation et la réquisition, la signature de l’armistice marque pour les entreprises de la Gironde occupée le début d’un dialogue complexe et fécond avec le gouvernement de Vichy et les autorités allemandes. Celles-ci font face à une polycratie franco-allemande, imposant des nouveaux cadres, administratifs et territoriaux, à leur activité. L’entreprise devient un enjeu réel de pouvoir. Apparaissent à la fois des réels points de convergence (aryanisation des « entreprises juives », rémunérations du travail) et d’importantes surfaces de tension (contrôle du port, concentration de la production, départ d’ouvriers pour l’Allemagne). Par ailleurs, le régime de Vichy ne lésine pas sur les moyens, en vue de faire de l’entreprise une vitrine idéologique (Révolution nationale) : cérémonies collectives, structures d’entraide, corporatismes, associations politiques, mouvements collaborationnistes. Armé d’un redoutable arsenal législatif et répressif, il parvient – avec le soutien des Allemands – à en faire un lieu d’exclusion, d’où sont violemment extraits les éléments jugés indésirables, que ce soit pour leurs activités politiques (les communistes) ou pour leur appartenance religieuse abusivement qualifiée de « raciale » (les juifs). À l’inverse, la stratégie consistant à faire de chaque établissement un lieu d’intégration à ses idéaux, ne rencontre qu’un succès mitigé. L’attachement des acteurs de l’entreprise à la personne même du maréchal Pétain, réel au début de la période, s’estompe sous l’effet des épreuves et des sujétions dont sont victimes les Girondins. De ce point de vue, la politique sociale de l’État français (Charte du travail et comités sociaux) ne lui permet pas – sauf exception – de « ramener » patrons et ouvriers dans le giron vichyste. Dans un contexte de graves pénuries (matières premières, main-d’œuvre, moyens de transport), les entreprises girondines cherchent bien des alternatives à ce qu’on appelle communément la « collaboration économique » : utilisation de produits de remplacement, reconversion des activités, réadaptation de l’appareil productif, essor des pratiques illicites (marché noir). Mais rares sont les patrons à ne pas devoir se poser la question de l’opportunité de proposer une offre de services à l’occupant. Cette offre est largement répandue, mais variable selon les métiers, les branches et les temps de l’Occupation. Les occupants tirent ainsi profit des atouts du tissu économique local, puisqu’ils parviennent à intégrer à leur économie de guerre les industries anciennement mobilisées pour la Défense nationale et plus encore les richesses tirées du sol girondin : le bois, la résine, le vin<br>While the Phoney War occasioned a first confrontation with regulations and requisition, the signing of the Armistice marked the start of a complex period for the enterprises in occupied Gironde, in that it prompted a fruitful dialogue with the Vichy government and the German authorities. These enterprises faced a French German polycracy, which imposed new administrative and territorial executives on their activities. Enterprise became a real power issue. There were points of convergence (the aryanisation of “Jewish enterprises”, the remuneration of work) as there were of conflict (the control of the port, the concentration of production, the workers' departure for Germany). Moreover, the Vichy regime did all it could to make enterprise an ideological showcase (“Révolution Nationale”): ceremonies, support groups, corporatism, political associations, collaborationist movements. Armed with a formidable legislative and repressive arsenal, it managed – with the support of the Germans – to create a place of exclusion, from which were violently removed, any elements that were judged undesirable either for their political activities (communists) or for their religious affiliation, abusively qualified as “racial” (Jews). On the contrary, the strategy which consisted in making each establishment a place of integration of its ideals, was not met with much success. The attachment that the actors of the enterprises had for Maréchal Pétain himself, which was very real in the beginning, soon faded with the trials and constraints that the people of Gironde had to suffer. From this point of view, the social policy of the French State (“Charte du Travail”) did not allow it – with some exceptions – to “bring” employers and workers back to the Vichy realm. In a context of severe shortage (primary goods, labour and means of transport), enterprises in Gironde looked for alternatives to what we commonly call the “economic collaboration”: use of products of replacement, reconversion of activities, readjustment of the productive machine, development of illicit practices (black market). Few entrepreneurs, however, missed the business opportunity that lay in offering their services to the occupying forces. These services were widespread, but varied according to jobs, fields of activity and times of the Occupation. In this way, the occupying forces benefited, from the strengths of the local economic fabric, since they managed to integrate into their war economy not only the industries that had earlier been mobilized for the “Défense Nationale” but also the natural resources of the land: wood, resin, wine

碩士<br>國立東華大學<br>電機工程學系<br>106<br>The current status of spectrum usage has been an uneven allocation, so we are in more urgent need of Cognitive Radio (CR) which is proposed to probing for spectrum holes to effectively make unlicensed users access the licensed bands so the idle periods of spectrum can be cut down. Hence, the spectrum bands will be effectively utilized. In this thesis, WINNER II path loss model is applied as an example for the simulation of wireless system. By using the antenna diversity, the cooperative spectrum sensing observes the probabilities of false alarm and detection between the primary user and cognitive relays. Then, a relay-assisted method over cognitive relays is applied to enhance the received signals in fusion center so that some signals in cognitive relays farther from fusion center can be relayed through the nearer cognitive relays and the overall bit error rate in fusion center can be improved. Finally, the decision fusion with different rules including AND, OR and Majority is applied to improve the accuracy of decision fusion.

Adaptive designs can improve the efficiency of drug development, but further research is needed before some are more widely implemented. One such design is a treatment-selection design, which begins with k treatment arms, but only a subset is carried forward after an interim analysis. The final analysis of the selected arm(s) is then performed using the data from both stages of the study. One issue with this design is ensuring the Type I error rate is controlled, but there have been a number of proposals that largely address this. A second drawback that has not yet been fully addressed is that the maximum likelihood estimate of the selected arm at the final analysis is often biased upward due to the selection method. Unbiased estimators already exist for this design, but methods with an acceptable balance between bias and mean squared error (MSE) are lacking. In this dissertation, two estimation approaches are proposed. The first is a parametric bootstrap resampling method in which the level of bias adjustment applied is driven by a comparison of the observed results to those expected when all arms have equal true means. The second approach is an empirical Bayes estimator that implements a novel limited translation function. These methods are compared to previously proposed approaches with respect to bias and MSE for studies that have either a normal or binomial endpoint. Both proposed methods are shown to exhibit reduced bias with reasonable MSE in some simulated scenarios, but the resampling method consistently shows similar, or improved, performance compared to previous approaches across the examined scenarios. The utility of this resampling method is further demonstrated by showing that it can be implemented when the arm with the second largest mean is selected for stage 2. It is also shown that the resampling method can be extended to when more than one arm is selected in stage 1, when there is a futility analysis, or when the study has a time-to-event endpoint. Recommendations on confidence intervals are also provided. The results demonstrate that the parametric bootstrap resampling method is a viable estimation approach for treatment-selection designs.