To see the other types of publications on this topic, follow the link: Whole food plant-based diet (WFPD).
Journal articles on the topic 'Whole food plant-based diet (WFPD)'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Whole food plant-based diet (WFPD).'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Adair, Kathleen E., and Rodney G. Bowden. "Ameliorating Chronic Kidney Disease Using a Whole Food Plant-Based Diet." Nutrients 12, no. 4 (April 6, 2020): 1007. http://dx.doi.org/10.3390/nu12041007.
Full textAbstract:
Novel approaches to ameliorating chronic kidney disease (CKD) are warranted as most patients are undiagnosed until they begin displaying symptoms of kidney failure. There is increasing evidence that a whole food plant-based (WFPB) diet may offer benefits that slow the progression of CKD, decrease the incidence cardiovascular disease, decrease rates of diabetes and obesity, and reduce inflammation and cholesterol, which in turn can delay kidney failure and the initiation of dialysis. While animal-based protein ingestion promotes an acidic environment, inflammation and renal hyperfiltration, study authors report plant-based protein can be alkaline-producing and anti-inflammatory and can contain renoprotective properties. Although there may be benefits to adopting a WFPB diet, macronutrient and micronutrient content should be carefully considered and adjusted to avoid malnutrition in CKD patients. Further research needs to be done in order to establish the biological plausibility and feasibility of a WFPB in individuals with diagnosed CKD.
2
McGoey-Smith, Kate J., Caldwell B. Esselstyn, and Andrew David McGoey-Smith. "Reversal of Pulmonary Hypertension, Diabetes, and Retinopathy after Adoption of a Whole Food Plant-Based Diet." International Journal of Disease Reversal and Prevention 1, no. 2 (September 18, 2019): 10. http://dx.doi.org/10.22230/ijdrp.2019v1n2a41.
Full textAbstract:
BACKGROUND: The whole food plant-based (WFPB) diet has been shown to be successful in reversing and preventing cardiovascular disease, type 2 diabetes, and some types of cancers. Here we report a case study of a patient showing significant reversal of both pulmonary hypertension (PH) and retinopathy, and total reversal of type 2 diabetes. This occurred 15 months after switching from a flexitarian diet to a WFPB diet. Furthermore, these reversals have now been maintained for a period of over six years without the use of targeted pharmaceutical interventions nor daytime oxygen. In particular, the patient’s six-minute walk test (6MWT) mean distance, visual acuity, and A1c measurements changed from 220 m, 20/200 ft and 15% respectively within three months of PH diagnosis to 409 m, 20/46 ft and 5.6% at 15 months after commencement of the WFPB diet. A total of 6 right heart catheterization procedures were performed: her mean pulmonary arterial pressure (mPAP) was 55 mmHg on the day of diagnosis and her last mPAP measurement was 40 mmHg, which was taken towards the beginning of the WFPB diet period. The reversals reported herein have been now maintained for a period of 6 years, without the use of targeted pharmaceuticals nor daytime oxygen. Although the patient was treated to several combinations PH drug interventions, spanning all three available biological pathways for promoting vasodilation, none of these combinations of drugs was as effective as the WFPB diet alone on her quality of life.CASE HISTORY: A 51-year-old Caucasian female voluntarily admitted herself in February 2007 to a local acute care facility exhibiting symptoms of type 2 diabetes, significant edema in her lower extremities; dyspnea at rest with exertion and during sleep, recurrent syncope, and neuropathic pain in both feet. Immediately after admission, the patient was treated with metformin and replaglinide to control her diabetes. In December 2007, the patient was diagnosed with idiopathic pulmonary arterial hypertension (IPAH) and commenced a series of targeted therapeutic drug interventions to treat her IPAH while consuming a flexitarian diet. None of these drug combinations was successful in improving her 6MWT result beyond 369m. After commencing two of thepharmaceutical interventions she experienced adverse side effects: loss of visual acuity to the point of legal blindness, 80 lb of fluid retention within 2 months. After five years post diagnosis of IPAH, the patient commenced consuming a WFPB diet that resulted in the disease reversals detailed above.CONCLUSIONS: Consumption of a WFPB diet resulted in better treatment outcomes for IPAH, retinopathy, and type 2 diabetes for the patient in this study compared with targeted drug interventions. is observation adds credence to the hypothesis that a WFPB diet is a viable method of ameliorating symptoms for PH patients. It is also consistent with recent animal model studies on ameliorating PH with consumption of dietary nitrates and a short-term clinical trial. While these data are hypothesis generating, a prospective clinical trial, including both 6MWT and cardiopulmonary hemodynamic measurements, is needed to fully demonstrate the efficacy of a WFPB diet on PH patient health.
3
Cheung, Joseph, Kripa Patel, and Melanie Lawson. "0590 Effect of a whole-food plant-based diet on daytime sleepiness in patients with obstructive sleep apnea." SLEEP 46, Supplement_1 (May 1, 2023): A259. http://dx.doi.org/10.1093/sleep/zsad077.0590.
Full textAbstract:
Abstract Introduction Consumption of diet rich in high saturated fats has been associated with a higher degree of daytime sleepiness. A whole-food, plant-based (WFPB) dietary pattern, which is low in saturated fat, has been shown to be beneficial in weight loss and other health conditions. Patients with obstructive sleep apnea (OSA) frequently experience excessive daytime sleepiness despite treatment. This study aims to assess the effect of a short term (21 days) WFPB diet on daytime sleepiness in patients with obstructive sleep apnea. Methods Patients were recruited from the Mayo Clinic Jacksonville sleep clinic who have a diagnosis of OSA who are on PAP therapy but have daytime sleepiness with Epworth Sleepiness Scale (ESS) score of 5 or above. Participants were asked to follow a strict WFPB diet for 21 days using the Fork Over Knives handbook as a guide. They were also asked to complete ESS before switching to and after completing a WFPB diet for 21 days. Results A total of 10 participants completed the 21-day WFPB diet. Eight out of ten participants had reported a reduction in daytime sleepiness. Overall, we found a mean decrease in ESS score of 3.8 in all participants, with 3 patients had a significant decrease in ESS score of ≥ 7. All participants completed the study with ≥ 90% adherence to a WFPB diet. In addition, participants also reported a mean weight loss of 4.2 kg. Two participants noted headaches during this 21-day period. Conclusion Significant improvement with daytime sleepiness was found in patients who switched to a WFPB diet for 21 days. No significant correlation between improvement in ESS and weight loss was found. Support (if any)
4
McGuire, Jeremy, Thomas Campbell, Nikesha Gilmore, Eva Culakova, Lindsey Jean Mattick, Michelle Christine Janelsins, Luke Joseph Peppone, and Erin Campbell. "A whole-food, plant-based dietary intervention and cognitive function in women with metastatic breast cancer." Journal of Clinical Oncology 41, no. 16_suppl (June 1, 2023): e24160-e24160. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e24160.
Full textAbstract:
e24160 Background: Disease-specific quality of life (QOL) is consistently regarded as one of the most important outcomes by women with metastatic breast cancer (mBC), and it predicts survival. Treatment-related symptoms such as cognitive impairment greatly impact QOL in women with mBC. Patients undergoing treatment for breast cancer are highly interested in diet and nutrition, but despite this high level of interest, very few trials have tested dietary interventions in women receiving systemic breast cancer therapy and; the majority of research has been conducted in survivors who have completed primary treatment. Given the limited treatment options for cognitive impairment we evaluated whether our results show a whole food plant based (WFPB) dietary intervention might improve perceived cognitive function (CF) in women undergoing treatment for metastatic breast cancer. Methods: Patients with stage 4 breast cancer receiving treatment were randomized 2:1 into 2 arms: 1) WFPB diet (n = 20) or 2) usual care (n = 10) for 8 weeks with assessments at baseline, and 8 weeks. Our WFPB diet consisted of an ad libitum whole-food, plant-based diet; 3 meals/day were provided, which included fruits, vegetables, whole grains, nuts/seeds and excluded meat, dairy, eggs, added oils, solid fats and most sugars. Patient reported outcomes for perceived CF were collected using FACT- COG and EORTC-QLQ-C30. Paired t-tests were used to assess within group changes from baseline to week 8. The between group difference (WFPB diet vs control) was assessed by ANCOVA model. Results: Patients on the WFPB diet began with a mean baseline score of 140.8 on the FACT-COG which significantly improved to 156.6 (p = 0.005) at 8-weeks post intervention. The reported minimally important difference (MID) between groups is (9.6) and we observed a clinically significant difference of 17.1 (p = 0.03). Similar results in CF were observed for EORTC-QLQ-C30. The baseline mean score of 73.3 was improved to 84.7 (p = 0.004) at 8-weeks post intervention. The reported MID between groups is (4) and we observed a clinically significant difference of 12.6 (p = 0.07), with no significant changes in perceived CF for the control group. Conclusions: Our 8-week WFPB diet resulted in clinically meaningful and statistically significant improvements in perceived cognitive function in women with metastatic breast cancer. A phase 3 clinical trial is needed to confirm the results of this novel intervention. Funding: 3UG1CA189961. Clinical trial information: NCT03045289 .[Table: see text]
5
Karlsen, Micaela, Gail Rogers, Akari Miki, Alice Lichtenstein, Sara Folta, Christina Economos, Paul Jacques, Kara Livingston, and Nicola McKeown. "Theoretical Food and Nutrient Composition of Whole-Food Plant-Based and Vegan Diets Compared to Current Dietary Recommendations." Nutrients 11, no. 3 (March 14, 2019): 625. http://dx.doi.org/10.3390/nu11030625.
Full textAbstract:
Public interest in popular diets is increasing, in particular whole-food plant-based (WFPB) and vegan diets. Whether these diets, as theoretically implemented, meet current food-based and nutrient-based recommendations has not been evaluated in detail. Self-identified WFPB and vegan diet followers in the Adhering to Dietary Approaches for Personal Taste (ADAPT) Feasibility Survey reported their most frequently used sources of information on nutrition and cooking. Thirty representative days of meal plans were created for each diet. Weighted mean food group and nutrient levels were calculated using the Nutrition Data System for Research (NDSR) and data were compared to DRIs and/or USDA Dietary Guidelines/MyPlate meal plan recommendations. The calculated HEI-2015 scores were 88 out of 100 for both WFPB and vegan meal plans. Because of similar nutrient composition, only WFPB results are presented. In comparison to MyPlate, WFPB meal plans provide more total vegetables (180%), green leafy vegetables (238%), legumes (460%), whole fruit (100%), whole grains (132%), and less refined grains (−74%). Fiber level exceeds the adequate intakes (AI) across all age groups. WFPB meal plans failed to meet the Recommended Dietary Allowances (RDA)s for vitamin B12 and D without supplementation, as well as the RDA for calcium for women aged 51–70. Individuals who adhere to WFBP meal plans would have higher overall dietary quality as defined by the HEI-2015 score as compared to typical US intakes with the exceptions of calcium for older women and vitamins B12 and D without supplementation. Future research should compare actual self-reported dietary intakes to theoretical targets.
6
Jakše, Boštjan, Barbara Jakše, Stanislav Pinter, Jernej Pajek, and Nataša Fidler Mis. "Characteristics of Slovenian Adults in Community-Based Whole-Food Plant-Based Lifestyle Program." Journal of Nutrition and Metabolism 2020 (August 1, 2020): 1–13. http://dx.doi.org/10.1155/2020/6950530.
Full textAbstract:
Objective. Adopting a plant-based diet (PBD) and lifestyle is healthy, sustainable, and increasingly popular, while also demanding. Individuals might face challenges to maintain this lifestyle. We aimed to determine the anthropometric values and lifestyle factors and motives of adults to adopt a whole-food, plant-based (WFPB) lifestyle by joining our ongoing, community-based, WFPB lifestyle program 0.5–10 years ago. Methods. We measured body mass index (BMI) and body fat percentage status (BF%) using bioimpedance. Lifestyle status was obtained by standardized electronic questionnaires. For evaluating the motives for following strict PBD, the participants were asked to rank 8 different motives (i.e., 8: the most-, 1: the least important). Setting. A cross-sectional study in Slovenia. Participants. A total of 151 healthy adults with an average age of 39.6 years (SD: 12.5 years). Results. The participants had an average BMI of 23.9 kg/m2 (SD: 3.8 kg/m2) and an average BF% of 22.3% (SD: 7.3%), were physically very active, with an average Long International Physical Activity Questionnaire (L-IPAQ) score of 5541.2 metabolic equivalents (METs) min/week (SD: 4677.0 METs min/week), having good sleep quality, with an average Pittsburgh Sleep Quality Index (PSQI) score of 2.7 (SD: 1.8), perceiving low stress, and with an average Perceived Stress Questionnaire (PSQ) score of 0.29 (SD: 0.1). We discovered no significant differences in lifestyle between participants who were involved in our WFPB lifestyle program for short, medium, or long periods of time. The motives for WFPB lifestyle included health benefits (score: 7.9/8), body mass management (6.3), eating to satiety (4.9), convenience (4.3), environmental concerns (4.1), affordability (3.7), animal ethics (3.6), and religious reasons (1.1). Conclusion. A WFPB lifestyle program for any length of time that includes an extensive support system provides favorable, long-term lifestyle changes.
7
Perzia, Brittany Marie, Joshua L. Dunaief, and David M. Dunaief. "Chronic migraine reversal and prevention with the LIFE diet: a nutrient dense whole food plant-based diet (WFPBD)." BMJ Case Reports 14, no. 12 (November 18, 2021): e243987. http://dx.doi.org/10.1136/bcr-2021-243987.
Full textAbstract:
We report a case of a 60-year-old man who struggled with frequent migraines for 12.5 years, which were refractory to all conventional therapies. Six months before initial consultation, these migraines become chronic. The patient was then advised to follow the Low Inflammatory Foods Everyday (LIFE) diet, a nutrient-dense, dark green leafy vegetable-rich, whole food plant-based diet. Within 2 months, his headache frequency declined from 18 to 24 headache days per month to 1, and he discontinued his preventive and abortive migraine medications. After 3 months, the patient had no headaches. These results far exceed the goal of migraine treatment with medication, which is to reduce migraine frequency by >50% per month. In addition, the results were durable; this patient has been migraine-free for 7.5 years. Serum beta-carotene more than tripled after the patient started the LIFE diet, consistent with its high content of dark green leafy vegetables. Weight, high-sensitivity C-reactive protein (hsCRP), complete blood count (CBC), hydration status, sodium and other electrolytes remained constant throughout the study.
8
Kim, Peter, Matthew Arnold, and Jasmine Gunti. "Five-Month Trial of Whole-Food Plant-Based Diet in a Patient With Coexisting Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome." American Journal of Lifestyle Medicine 15, no. 3 (February 16, 2021): 230–37. http://dx.doi.org/10.1177/1559827621993748.
Full textAbstract:
Introduction: Nutritional intervention, such as a whole-food plant-based (WFPB) diet, is suggested to improve symptoms of autoimmune disorders. Its effects on neuromuscular junction (NMJ) diseases are less known. Case Description: A 56-year-old female with a combined myasthenia gravis and Lambert-Eaton myasthenic syndrome presented with persistent musculoskeletal weakness and pain, fatigue, and diminished concentration. Methods: A WFPB diet was implemented for 5 months in this case study. Functionality, biometrics, and quality of life were assessed at regular intervals via blood work, vital signs, and patient surveys. Results: After 10 weeks, 2 medications were de-prescribed due to improvement in blood glucose levels and blood pressure readings. Neuromuscular symptoms lessened as measured by the Myasthenia Gravis Illness Index. Weight loss of 18.7 pounds was achieved. No deterioration in physical activity was reported throughout the 5-month trial of WFPB diet. Discussion: Our results have implications that an individualized dietary strategy may be considered as one component of management of NMJ diseases. The effects of WFPB diet on NMJ diseases remain inconclusive.
9
Karlsen, Micaela C., Alice H. Lichtenstein, Christina D. Economos, Sara C. Folta, Remco Chang, Gail Rogers, Paul F. Jacques, Kara A. Livingston, and Nicola M. McKeown. "Participant characteristics and self-reported weight status in a cross-sectional pilot survey of self-identified followers of popular diets: Adhering to Dietary Approaches for Personal Taste (ADAPT) Feasibility Survey." Public Health Nutrition 23, no. 15 (July 27, 2020): 2717–27. http://dx.doi.org/10.1017/s1368980020001330.
Full textAbstract:
AbstractObjective:To describe characteristics of self-identified popular diet followers and compare mean BMI across these diets, stratified by time following diet.Design:Cross-sectional, web-based survey administered in 2015.Setting:Non-localised, international survey.Participants:Self-selected followers of popular diets (n 9019) were recruited to the survey via social media and email announcements by diet community leaders, categorised into eight major diet groups.Results:General linear models were used to compare mean BMI among (1) short-term (<1 year) and long-term (≥1 year) followers within diet groups and (2) those identifying as ‘try to eat healthy’ (TTEH) to all other diet groups, stratified by time following the specific diet. Participants were 82 % female, 93 % White and 96 % non-Hispanic. Geometric mean BMI was lower (P < 0·05 for all) among longer-term followers (≥1 year) of whole food, plant-based (WFPB), vegan, whole food and low-carb diets compared with shorter-term followers. Among those following their diet for 1–5 years (n 4067), geometric mean BMI (kg/m2) were lower (P < 0·05 for all) for all groups compared with TTEH (26·4 kg/m2): WFPB (23·2 kg/m2), vegan (23·5 kg/m2), Paleo (24·6 kg/m2), vegetarian (25·0 kg/m2), whole food (24·6 kg/m2), Weston A. Price (23·5 kg/m2) and low-carb (24·7 kg/m2).Conclusion:Our findings suggest that BMI is lower among individuals who made active decisions to adhere to a specific diet, particularly more plant-based diets and/or diets limiting highly processed foods, compared with those who simply TTEH. BMI is also lower among individuals who follow intentional eating plans for longer time periods.
10
Campbell, Erin, Thomas Campbell, Eva Culakova, Nellie Wixom, Joseph Guido, Lisa Blanchard, James Fetten, Michelle Janelsins, Karen Mustian, and Luke Peppone. "Abstract P4-07-31: A whole food, plant-based (WFPB) dietary intervention to improve cardiometabolic and cancer-related outcomes in women with breast cancer." Cancer Research 83, no. 5_Supplement (March 1, 2023): P4–07–31—P4–07–31. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-07-31.
Full textAbstract:
Abstract Background: With dramatically rising obesity rates in the US, obesity at breast cancer diagnosis is common; further compounding the problem is that breast cancer treatment often results in additional weight gain. Among women undergoing breast cancer treatment, both obesity at diagnosis and post-diagnosis weight gain are associated with increased all-cause mortality and increased breast cancer mortality. We tested a WFPB dietary intervention in metastatic breast cancer patients to improve cardiometabolic and cancer-related outcomes, as it has been shown to reduce weight and improves cardiometabolic health in overweight and obese individuals. Methods: Women with stage 4 breast cancer receiving treatment were randomized 2:1 into 2 arms: 1) a WFPB diet (N=21) or 2) usual diet (N=11) for 8 weeks with assessments at baseline, 4, and 8 weeks. Our WFPB diet consisted of an ad libitum whole food, plant-based diet; 3 meals/day were provided to WFPB subjects, which included fruits, vegetables, whole grains, nuts and seeds, and excluded meat, dairy, eggs, and added oils/solid fats. WFPB subjects received weekly education regarding diet. Subjects in the usual care group were asked to continue their usual diet for the next 8 weeks. Outcomes include cardiometabolic risk factors, related sex hormones, and cancer progression markers. Effects of the WFPB diet on the outcomes were assessed by comparing marginal means by arm estimated at 8 weeks from the analysis of covariance model controlling for the baseline value. Results: Of the 32 subjects randomized, 30 subjects (20 WFPB and 10 usual care) completed all 3 assessments. Reductions in weight, BMI, total cholesterol, and LDL cholesterol were statistically significant as well as clinically meaningful, both within the WFPB group and between the groups. In the WFPB group, subjects lost a mean of 6.2% of their body weight versus 0.7% body weight loss in the control group (p< 0.01). LDL cholesterol was reduced by a mean of 20.0% in the WFPB subjects versus a 10.6% increase in control subjects (p< 0.01). Reductions in insulin and HOMA-IR, a measure of insulin sensitivity, were statistically significant within the WFPB group and trended towards significance between the groups. Sex hormone binding globulin (SHBG) levels increased significantly both within the WFPB group and between groups. There was a significant decrease in both IGF-1 and free testosterone within the WFPB group from baseline to week 8. Conclusions: Our WFPB intervention resulted in improvements in several cardiometabolic and hormonal markers. The intentional weight loss, which was clinically large given the duration of the trial, was accompanied by reduced cholesterol, insulin resistance, free testosterone, and IGF-1. Given the moderate to large effect sizes noted, further study is warranted to evaluate the sustainability of benefits over time and to assess their potential impact on cancer-related outcomes. Table 1: Cardiometabolic and Cancer-Related Outcomes Citation Format: Erin Campbell, Thomas Campbell, Eva Culakova, Nellie Wixom, Joseph Guido, Lisa Blanchard, James Fetten, Michelle Janelsins, Karen Mustian, Luke Peppone. A whole food, plant-based (WFPB) dietary intervention to improve cardiometabolic and cancer-related outcomes in women with breast cancer [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P4-07-31.
11
Gerber, Suzannah, Gail Rogers, Kara Staffier, Micaela Karlsen, Sara Folta, Paul Jacques, Elena Naumova, and Nicola McKeown. "Adherence, Compliance, and Diet Quality Among Popular Diet Followers." Current Developments in Nutrition 6, Supplement_1 (June 2022): 364. http://dx.doi.org/10.1093/cdn/nzac054.019.
Full textAbstract:
Abstract Objectives 1. To compare diet quality of vegan, vegetarian, paleo, and whole-food plant-based (WFPB) diets; 2. To examine how adherence varies by diet and relates to quality and diet duration; 3. To examine how compliance varies by diet and relates to quality, adherence, and duration. Methods Analysis was conducted on a subsample of ADAPT participants (n = 1392) who completed a demographics and food frequency questionnaire (FFQ; DHQ-II). After excluding implausible energy intake (600 ≤ KCAL < 5,000), the final sample was 1291 (vegan [n = 355]; vegetarian [n = 90]; WFPB [n = 710]; paleo [n = 136]). Diet quality was measured with HEI and AHEI. Duration was categorized as short [<2 years (n = 501)]; moderate [2 to <7 y (n = 200)]; and long-term [7–10 + y (n = 592)]. A self-report adherence score was derived from questions targeting commitment to diet, ranging from 0–32. Compliance score for each diet was derived from reported intakes and DHQ-II (i.e., diet-specific restrictions), and data were %-based standardized. Models were adjusted for age and sex; select models were adjusted for diet duration. Results Mean (SD) HEI score was high in all plant-based diets, highest for WFPB 76.7(5.8), vegan 75.7 (6.5), vegetarian 72.6 (9.2), compared to paleo 62.5 (8.5); and with a similar ranking for AHEI. Vegans had highest mean adherence 23.5 (2.8) and paleos the lowest 20.0 (3.3). Vegetarians had highest mean compliance 71% (9) and WFPB lowest 53% (10). Compliance was positively associated with HEI score for WFPB and vegan with one percentage point of compliance associated with a 6.4-point increase in HEI for WFPB (SE ± 2, p < .004) and 17.1 for vegan (SE ± 4, p < .0001). For every point increase in compliance, adherence improved (5.4 ± 0.8, p < .0001) in the full sample, and by diet group. Diet duration was significantly associated with adherence in all but vegetarian. No relationship was observed between duration and compliance within diet. Conclusions WFPB and vegan diets had the highest diet quality; all four had higher mean HEI than reported average in US adults (HEI = 59). Findings suggest that even imperfect compliance to plant-based diets is associated with greater diet quality. Diet adherence is a complex component of eating behavior, however reported adherence appears to predict higher compliance and longer maintenance. Funding Sources USDA Cooperative Agreements; NIFA National Needs Fellowship.
12
Jakše, Boštjan, Barbara Jakše, Uroš Godnov, and Stanislav Pinter. "Ongoing Community-Based Whole-Food, Plant-Based Lifestyle Effectively Preserves Muscle Mass during Body Mass Loss." Obesities 2, no. 2 (April 3, 2022): 157–70. http://dx.doi.org/10.3390/obesities2020014.
Full textAbstract:
Body fat and muscle mass showed opposing associations with mortality. The results of research on the effectiveness of popular body mass (BM) loss diets in obese subjects showed 20 to 30% loss of muscle mass within the total BM loss; conversely, when the subjects used a whole-food, plant-based (WFPB) diet, the loss was up to 42%. Therefore, we suggest an improvement. The aim of this retrospective analysis of data was to examine the assessment of changes in the body composition of 217 participants from all over Slovenia who joined our ongoing, community-based WFPB lifestyle programme from 2016 to 2021 and underwent two successive measurements of medically approved bioelectrical impedance. The WFPB lifestyle programme consisted of (i) nutrition, (ii) physical activity (PA) and (iii) a support system. The primary outcomes included the (vector of) change of body fat mass (BFM) per body height (BH), fat-free mass (FFM) per BH and whole-body phase angle (PhA) from the initial values to the first follow-up (FU) of the whole sample and for both sexes. Further, we examined the FFM change within the total BM loss according to their BMI classification and depending on how much BM they lost (5 kg < BM ≥ 5 kg) within the FU time (103.6 ± 89.8 day). Participants experienced a decrease in BFM per BH (−0.02 ± 0.02 kg/cm, p < 0.001), no change in FFM and an increase in PhA (0.2 ± 0.7°, p < 0.001). Importantly, the participants in the obesity BMI class achieved only partial FFM preservation (−1.5 ± 3.6 kg, p = 0.032 of FFM loss (20%) within −7.5 ± 6.1 kg, p < 0.001 of BM loss). However, the participants who lost BM < 5 kg had a significantly increased FFM (0.8 ± 3.2 kg, p = 0.001 of FFM (57%) within −1.4 ± 1.8 kg, p < 0.001 of BM loss), whereas the participants who lost BM ≥ 5 kg experienced a decrease in FFM (−2.2 ± 3.9 kg, p < 0.001 of FFM (−25%) within −8.8 ± 5.2 kg, p < 0.001 of BM loss). To conclude, the WFPB lifestyle, on average, effectively preserved FFM during BM and/or BFM loss among the normal and pre-obesity BMI classes but only partially among the obese BMI class and those who lost ≥ 5 kg of BM. Importantly, a customized PA strategy is needed for obese BMI class participants, where general resistance training is not possible or safe in order to preserve their muscle mass more effectively. In addition, muscle mass preservation is important for further improvements of BM, body composition and visual body image.
13
Smith, Morgen, Nicholas Wright, Patrick McHugh, and Bruce Duncan. "Remission of long-standing livedoid vasculopathy using a whole foods plant-based diet with symptoms recurrent on re-challenge with standard Western diet." BMJ Case Reports 14, no. 2 (February 2021): e237895. http://dx.doi.org/10.1136/bcr-2020-237895.
Full textAbstract:
A 63-year-old woman presented with ulcerations of both lower legs. Symptom onset was 2006. In 2013 she saw a dermatologist and a biopsy suggested livedoid vasculopathy. In 2016 a whole food plant-based diet (WFPB) was advised as a potential treatment in the community setting. The patient changed her diet accordingly, but was not otherwise treated. The symptoms remitted completely with close adherence to the WFPB diet and recurred on multiple occasions associated with poor dietary adherence. There was a self-identified dose–response relationship with degree of adherence and number and intensity of flares. There were no known adverse side effects from the diet change, although the patient felt adherence to be difficult at times. The mechanism is not completely clear; we speculate that the dietary changes directly affect vascular endothelial health, which in turn affects propensity towards a prothrombotic state. More research is needed to elucidate potential mechanisms.
14
Campbell, Thomas, Erin Campbell, Eva Culakova, Nellie Wixom, Joseph Guido, Lisa Blanchard, Michelle Janelsins, Karen Mustian, James Fetten, and Luke Peppone. "Abstract P5-07-07: Feasibility of a Whole-Food, Plant-Based Intervention Among Women with Metastatic Breast Cancer and its Effect on Patient-Reported Outcomes." Cancer Research 83, no. 5_Supplement (March 1, 2023): P5–07–07—P5–07–07. http://dx.doi.org/10.1158/1538-7445.sabcs22-p5-07-07.
Full textAbstract:
Abstract Background: Women diagnosed with breast cancer commonly gain weight during and after treatment; this obesity/weight change is associated with decreased quality of life (QOL) and other patient-reported outcomes (PROs) such as cognitive dysfunction. Whole-food, plant-based (WFPB) dietary interventions lead to weight loss and cardiometabolic improvements, but their feasibility among metastatic breast cancer patients and their effect on cancer-related PROs have not previously been studied. Methods: Women with stage 4 breast cancer and stable disease were randomized 2:1 into: 1) a WFPB dietary intervention (N=21) or 2) usual care (N=11) for 8 weeks with assessments at baseline, 4 and 8 weeks. Our WFPB diet consisted of weekly educational visits and an ad libitum whole-food, plant-based diet. Three prepared meals a day were provided for the duration of the trial. The diet included fruits, vegetables, whole grains, legumes, nuts and seeds and excluded meat, dairy, eggs, and added oils/solid fats. Effects of the WFPB diet on the outcomes were assessed by comparing marginal means by arm estimated at 8 weeks from the analysis of covariance model controlling for baseline. Results: Of 32 subjects randomized, 20 intervention subjects and 10 control subjects completed all 3 assessments. Baseline and week 8 dietary intake among the intervention subjects is shown in table 1. Cognitive function, as measured by the Functional Assessment of Cancer Therapy – Cognitive Function (FACT-COG) questionnaire and a modified MD Anderson Symptom Inventory (MDASI), showed significant improvement within the intervention group as well as in comparison to the control group (Table 2). Overall quality of life, emotional and physical wellbeing, and breast cancer-specific symptoms, as measured by Functional Assessment of Cancer Therapy – Breast (FACT-B) questionnaire improved significantly within the intervention group. Mean fatigue was lower at 8 weeks within the intervention group as measured by the Brief Fatigue Inventory (BFI), but this did not reach statistical significance (p=0.10). When intervention subjects were asked, “On a scale from 1 to 10 [1 being “would not recommend” and 10 being “highly recommend”], how strongly would you recommend that other cancer patients be given this type of nutrition and support intervention if they were able and willing to participate?” participants’ mean score was 9.5. Conclusion: Our WFPB intervention was feasible and acceptable, with high compliance despite asking subjects to make major changes in dietary intake. Clinically and statistically significant improvements in several PROs, including cognitive function, overall QOL, physical and emotional wellbeing were noted for those in the WFPB group. Given the benefits to QOL and PROs, longer studies are required to demonstrate durability of behavior changes and outcomes. Table 1: Nutrient Intake of the Intervention Group (n=19*) *One participant was missing one three-day food record Table 2. Patient-Reported Outcomes Citation Format: Thomas Campbell, Erin Campbell, Eva Culakova, Nellie Wixom, Joseph Guido, Lisa Blanchard, Michelle Janelsins, Karen Mustian, James Fetten, Luke Peppone. Feasibility of a Whole-Food, Plant-Based Intervention Among Women with Metastatic Breast Cancer and its Effect on Patient-Reported Outcomes [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P5-07-07.
15
Jakše, Boštjan, Barbara Jakše, Stanislav Pinter, Borut Jug, Uroš Godnov, Jernej Pajek, and Nataša Fidler Mis. "Dietary Intakes and Cardiovascular Health of Healthy Adults in Short-, Medium-, and Long-Term Whole-Food Plant-Based Lifestyle Program." Nutrients 12, no. 1 (December 24, 2019): 55. http://dx.doi.org/10.3390/nu12010055.
Full textAbstract:
An effective lifestyle strategy to reduce cardiovascular diseases risk (CVD) factors is needed. We examined the effects of a whole-food plant-based (WFPB) lifestyle program on dietary intake and cardiovascular (CV) risk factors in 151 adults (mean 39.6 (SD 12.5) years). Adherence was categorised into short-, medium- and long-term (years: (0.5–<2), (2–<5) and (5–10)), for both genders separately. Dietary intakes were assessed, fasting blood lipids and blood pressure (BP) were measured, and % participants reaching guideline recommended targets for LDL-cholesterol, triglycerides and BP in the primary CVD prevention was assessed. There were no statistically significant differences in intakes of energy and most nutrients among participants (both genders), that were short-, medium- and long term in our program. Diet was mainly composed of unprocessed vegetables/fruits, whole grains, legumes, potatoes, and nuts/seeds. LDL-cholesterol, triglycerides, systolic and diastolic BP were within targets for: 93%, 97%, 88% and 95% participants, respectively. In females (vs. males), total- and HDL-cholesterol were higher (mean): 3.8 (SD 0.7) vs. 3.4 (SD 0.9), p = 0.002 and 1.5 (SD 0.3) vs. 1.1 (SD 0.2) mmol/L, p < 0.001), systolic BP was lower (113 (SD 11) vs. 120 (SD 10) mmHg, p = 0.001), while there was no difference in diastolic BP (71 (SD 9) vs. 72 (SD 8) mmHg, p = 0.143). More females vs. males reached target triglycerides (99% vs. 91%, p = 0.021) and systolic BP (92% vs. 79%, p = 0.046), while similar females and males reached target LDL-cholesterol (94% vs. 91%, p = 0.500) and diastolic BP (93% vs. 100%, p = 0.107). Participation in our WFPB lifestyle program is associated with favourable dietary intakes, safety markers, and CV risk factor profiles.
16
Toso, Shawn, Julie Kurtz, William Reichert, Raymond Migrino, and Diane Parrington. "Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors in Veterans (Part 1)." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1352. http://dx.doi.org/10.1093/cdn/nzaa059_069.
Full textAbstract:
Abstract Objectives A short-term intervention designed to test the feasibility of Veterans to adopt a whole-food, plant-based (WFPB) diet has not been tested. The specific aims of this study were to (1) determine the feasibility of Veterans adopting a WFPB diet within four weeks, following a plant-strong protocol, (2) determine the effectiveness on participant's cardiovascular risk factors and dietary patterns and (3) compare the results to Veterans following the American Heart Association or Diabetic Diets. Methods Prospective, nonrandomized, pilot study of overweight or obese hyperlipidemic Veterans naive to lipid lowering drugs. The first 4 participants were assigned the control group, the next 6 were assigned the intervention. Participants in the control group who met inclusion/exclusion criteria after completion of control intervention could cross-over into the intervention group. The intervention was a four-week program which included individual education on a WFBP diet, (including menu planning and making grocery lists), a grocery store tour, cooking skills, substitutions and food preparation, and challenges dining out. Participants in the control arm received the standard of care. Anthropometrics, biochemical measures, and dietary intake patterns were obtained at baseline and five weeks. Results Eight male Veterans (mean 57 years old) completed the study, (n = 4 control, n = 6 intervention, 2 crossed over). Ability to adopt a WFBP diet was 83%. Data from diet adopters were compared to the control. Both groups had a significant decrease in LDL from baseline (12% control and 19% in intervention, P = 0.04 each). Veterans in the intervention group had a significant decrease in weight (3%, P = 0.04) and reported: gassiness, better digestion, more energy and better sleep. Conclusions Veterans were able to adopt a WFBP diet and experienced a favorable change in LDL cholesterol. Resources needed to conduct the intervention preclude widespread implementation. Further research is needed to determine if less resource intensive programs are feasible and effective for long-term sustainability and determine which Veterans may benefit most. Funding Sources Carl T Hayden Medical Research Foundation.
17
Jacobs, Nicole, Katie Hootman, Victoria Fischer, Nadja Pinnavaia, Karen Sfanos, Jones T. Nauseef, Ana M. Molina, et al. "Whole-food plant-based diet (WFPBD) to control weight and metabo-inflammation in overweight/obese men with prostate cancer (PC) receiving androgen deprivation therapy (ADT): A multi-center randomized control trial." Journal of Clinical Oncology 41, no. 16_suppl (June 1, 2023): TPS5098. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.tps5098.
Full textAbstract:
TPS5098 Background: Obesity promotes a chronic inflammatory state that is associated with PC progression. ADT can cause significant side effects including weight gain, accumulation of body fat, insulin resistance, and an increased risk of diabetes and cardiovascular disease. A WFPBD has been shown to promote weight loss, decrease chronic inflammation, and shift gut microbial profiles to a microbiome that promotes insulin sensitivity. We hypothesize that a WFPBD and behavior intervention will promote weight loss and a reduction in adiposity in overweight/obese patients with PC on ADT and will decrease biomarkers of metabo-inflammation; and that a WFPBD, which is enriched in fiber, will modulate the fecal microbiota and metabolites, and alter study participants’ serum metabolome. Correlative studies will offer insight into the impact of nutrition on metabolic pathways that are known to be affected by PC, ADT and/or excess body fat, including steroid metabolism, ketogenesis, and fatty acid metabolism. Methods: Key eligibility criteria include pts with PC with a BMI ≥ 27 receiving ADT with an LHRH/GnRH analogue for >24 weeks pre-study (+ androgen receptor pathway inhibitor for >3 mos) with anticipation of >26 more weeks of ADT. 60 patients randomized 1:1 between two cohorts. Cohort 1: pts receive 12 prepared meals (provided by Plantable) per weeks 1-4 and 6 meals weeks 5-8 plus Plantable coaching, nutritional counseling and education to assist in self-prepping plant-based meals (weeks 9-26); Cohort 2 (control): pts receive general nutritional counseling from a Registered Dietician weekly for 8 weeks, then monthly x 4. Collection of baseline and serial measurements (pre-intervention, weeks 4, 8 and 26) including weight, serum carotenoid levels (to monitor dietary compliance), dual energy x-ray absorptiometry (DXA) scans, MnSOD polymorphisms, and biomarkers of inflammation and metabolism. The primary comparison is weight loss at 4 weeks (with an 80% power to detect an effect size 0.74 standard deviations with a 2-sided significance level of 0.05 using a two-sample t-test). Secondary objectives will assess and compare changes in: a) biomarkers of metabolic disorders (Hemoglobin A1c, fasting insulin/glucose) and cardiovascular risk (LDL cholesterol, HDL cholesterol, triglycerides); b) pro-inflammatory markers (IL-6, hsCRP) and adipokines (leptin, adiponectin); c) fecal microbiota; and d) quality of life measurements. Exploratory objectives will assess the effects of a WFPBD on serum and fecal metabolomics and on clonal hematopoiesis. Trial is open at Weill Cornell Medicine (WCM), John Hopkins University and Columbia University. First pt enrolled at WCM September 2022. Funding support from the Prostate Cancer Foundation; PC Clinical Trials Consortium c22-301. Clinical trial information: NCT05471414 .
18
Clinton, Chelsea M., Shanley O’Brien, Junwen Law, Colleen M. Renier, and Mary R. Wendt. "Whole-Foods, Plant-Based Diet Alleviates the Symptoms of Osteoarthritis." Arthritis 2015 (February 28, 2015): 1–9. http://dx.doi.org/10.1155/2015/708152.
Full textAbstract:
Objective. To evaluate the effectiveness of a whole-foods, plant-based diet (WFPB) to reduce symptoms of osteoarthritis. Methods. Six-week, prospective randomized open-label study of patients aged 19–70 with osteoarthritis. Participants were randomized to a WFPB (intervention) or continuing current diet (control). Outcomes were assessed by mixed models analysis of participant self-assessed weekly SF-36v2 domain t scores, weekly Patient Global Impression of Change (PGIC) scales, and mean weekly Visual Analog Scale (VAS) pain assessment. Mixed models analysis also evaluated pre-post change from baseline level for standard clinical measures: weight, BMI, body temperature, pulse, and blood pressure. Results. Forty participants were randomized. Thirty-seven of them, 18 control and 19 intervention, completed the study. The intervention group reported a significantly greater improvement than the control group in SF-36v2 energy/vitality, physical functioning, role physical, and the physical component summary scale. The differences between the intervention and control PGIC scales were statistically significant over time. Intervention group improvement in VAS weekly mean was also significantly greater than that of the control group from week 2 onward. Conclusion. Study results suggest that a whole-foods, plant-based diet significantly improves self-assessed measures of functional status among osteoarthritis patients.
19
Shah, Urvi A., Daniel Alicea, Peter A. Adintori, Miranda Burge, Jenna Blaslov, Andriy Derkach, Sham Mailankody, et al. "A Pilot Plant-Based Dietary Intervention in Overweight and Obese Patients with Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma- the Nutrition Prevention (NUTRIVENTION) Study." Blood 138, Supplement 1 (November 5, 2021): 4759. http://dx.doi.org/10.1182/blood-2021-151049.
Full textAbstract:
Abstract Background and Scientific Rationale: Multiple myeloma (MM) is often preceded by the premalignant conditions monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). Obesity, low adiponectin levels, and diets high in inflammatory, insulinemic foods or lacking plant-based foods are known risk factors for the development of MGUS/SMM, as well as for progression to MM. Therefore, there is an opportunity to study a dietary intervention in cancer progression among patients with MGUS/SMM, for which the standard of care is observation even though some patients will eventually progress to MM. This is a pilot nutrition-based intervention study of a whole food, plant-based diet (WFPBD) in overweight and obese MGUS and SMM patients to enable weight loss, assess associated changes in disease biomarkers, epigenetics, and the gut microbiome. We expect that the findings will enable larger lifestyle-based studies of prevention and survivorship in plasma cell disorders. Study Design and Methods: This is a single-arm, single-center pilot study of a WFPBD for 12 weeks and nutrition counseling for 24 weeks which will enroll 20 patients (Figure). Clinical trial registry number: NCT04920084, actively recruiting. Study Population and Inclusion Criteria i) SMM or MGUS ii) Body mass index ≥25 iii) Monoclonal protein spike ≥0.2 g/dL or abnormal free light chain ratio with increased level of the appropriate involved light chain iv) ECOG performance status 0-3 v) Willingness to comply with study-related procedures Statistical Methods: The average weight loss from baseline at 12 weeks will be reported as sample mean along with 95% confidence interval. Adherence will be estimated by sample proportion, with confidence intervals based on exact binomial distribution. Patients who have completed evaluation at 12 weeks will be evaluable for the weight loss outcome. All patients who have received at least one WFPBD intervention will be evaluable for adherence assessment. We will consider this intervention promising if 1) we detect weight loss at 12 weeks and 2) estimated adherence to the intervention is ≥70%. Study Treatment: For 12 weeks, patients will receive two premade meals per day, for lunch and dinner for 6 days per week, prepared and shipped by Plantable. The meals will have a low glycemic index and contain vegetables, whole grains, and plant-based fats that have undergone minimal processing. Detailed recommendations for snacks and breakfasts meeting the standard of a WFPBD will also be given to supplement their daily calorie needs with access to an online portal or phone application from Plantable which contains education materials and access to a coach daily for 24 weeks. Patients will receive dietary education and counseling from a research dietitian every 2 weeks for the 12-week intervention period. Endpoints: Primary: - To determine the feasibility of a WFPBD, as measured by weight loss and adherence at 12 weeks. Secondary: - To determine the feasibility of a WFPBD, as measured by safety, and quality of life. - To assess weight loss at 24, and 52 weeks. - To assess alterations in metabolic, and myeloma markers. Exploratory: - To assess alterations in T cell and plasma cell epigenetic markers - To assess alterations in the fecal microbiome - To assess changes in body composition as determined by PET imaging and correlate with weight change as well as disease markers. Figure 1 Figure 1. Disclosures Shah: Janssen: Research Funding; Celgene/BMS: Research Funding. Adintori: Vidafuel Inc.: Current holder of stock options in a privately-held company. Mailankody: Jansen Oncology: Research Funding; Physician Education Resource: Honoraria; Bristol Myers Squibb/Juno: Research Funding; Plexus Communications: Honoraria; Fate Therapeutics: Research Funding; Takeda Oncology: Research Funding; Allogene Therapeutics: Research Funding; Legend Biotech: Consultancy; Evicore: Consultancy. Korde: Medimmune: Membership on an entity's Board of Directors or advisory committees; Amgen: Research Funding. Hultcrantz: Intellisphere LLC: Consultancy; Amgen: Research Funding; GlaxoSmithKline: Membership on an entity's Board of Directors or advisory committees, Research Funding; Daiichi Sankyo: Research Funding; Curio Science LLC: Consultancy. Hassoun: Celgene, Takeda, Janssen: Research Funding. D'Souza: Sanofi, Takeda, Teneobio, CAELUM, Prothena: Research Funding; Imbrium, Pfizer, BMS: Membership on an entity's Board of Directors or advisory committees; Janssen, Prothena: Consultancy. Giralt: AMGEN: Membership on an entity's Board of Directors or advisory committees; PFIZER: Membership on an entity's Board of Directors or advisory committees; JAZZ: Membership on an entity's Board of Directors or advisory committees; GSK: Membership on an entity's Board of Directors or advisory committees; SANOFI: Membership on an entity's Board of Directors or advisory committees; Actinnum: Membership on an entity's Board of Directors or advisory committees; JENSENN: Membership on an entity's Board of Directors or advisory committees; BMS: Membership on an entity's Board of Directors or advisory committees; CELGENE: Membership on an entity's Board of Directors or advisory committees. Iyengar: Novartis: Consultancy; Seattle Genetics: Consultancy; Novartis: Research Funding. Landgren: Janssen: Other: IDMC; Janssen: Honoraria; Amgen: Honoraria; Celgene: Research Funding; Janssen: Research Funding; Amgen: Research Funding; Takeda: Other: IDMC; GSK: Honoraria. van den Brink: Pluto Therapeutics: Current holder of stock options in a privately-held company, Other: has consulted, received honorarium from or participated in advisory boards ; Novartis (Spouse): Other: has consulted, received honorarium from or participated in advisory boards; Forty-Seven, Inc.: Honoraria; MagentaTherapeutics: Honoraria; Da Volterra: Other: has consulted, received honorarium from or participated in advisory boards; Wolters Kluwer: Patents & Royalties; Ceramedix: Other: has consulted, received honorarium from or participated in advisory boards ; Notch Therapeutics: Honoraria; DKMS (nonprofit): Other; Pharmacyclics: Other; Kite Pharmaceuticals: Other; GlaskoSmithKline: Other: has consulted, received honorarium from or participated in advisory boards; Lygenesis: Other: has consulted, received honorarium from or participated in advisory boards ; Nektar Therapeutics: Honoraria; Rheos: Honoraria; Seres: Other: Honorarium, Intellectual Property Rights, Research Fundingand Stock Options; Amgen: Honoraria; Therakos: Honoraria; WindMILTherapeutics: Honoraria; Juno Therapeutics: Other; Merck & Co, Inc: Honoraria; Frazier Healthcare Partners: Honoraria; Priothera: Research Funding; Synthekine (Spouse): Other: has consulted, received honorarium from or participated in advisory boards; Jazz Pharmaceuticals: Honoraria. Lesokhin: pfizer: Consultancy, Research Funding; Genetech: Research Funding; Trillium Therapeutics: Consultancy; Behringer Ingelheim: Honoraria; Serametrix, Inc: Patents & Royalties; bristol myers squibb: Research Funding; Janssen: Honoraria, Research Funding; Iteos: Consultancy.
20
Abdul Aziz, Muhammad, Zahid Ullah, Muhammad Adnan, Renata Sõukand, and Andrea Pieroni. "The Fading Wild Plant Food–Medicines in Upper Chitral, NW Pakistan." Foods 10, no. 10 (October 18, 2021): 2494. http://dx.doi.org/10.3390/foods10102494.
Full textAbstract:
The subject of food–medicines (foods ingested in order to obtain a therapeutic activity or to prevent diseases) is garnering increasing attention from both ethnobiologists and ethnopharmacologists as diet-related chronic diseases are one of the major problems resulting in a large proportion of deaths globally, which calls for interest from the scientific community to make sensible decisions in the field of food and medicine. In this regard, the current study is an important attempt at providing baseline data for developing healthy and curative food ingredients. This study aimed at recording the culinary and medicinal uses of wild food plants (WFPs) in the remote Mastuj Valley, located at the extreme north of Chitral District, Pakistan. An ethnobotanical survey was completed via 30 in-depth semi-structured interviews with local knowledge holders to record the food and medicinal uses of WFPs in the study area. A total of 43 WFPs were recorded, most of which were used as cooked vegetables and raw snacks. Leaves were the most frequently used plant part. A remarkable proportion (81%) of use reports for the recorded wild plant taxa were quoted as food–medicines or medicinal foods, while very few were reported as either food or medicines, without any relationship between uses in these two domains. Previous ethnomedicinal studies from nearby regions have shown that most of the recorded wild plants have been used as medicines, thus supporting the findings of the current study. A literature survey revealed that many of the reported medicinal uses (33%) for the quoted WFPs were not verifiable on PubMed as they have not been studied for their respective medicinal actions. We observed that most of the plants quoted here have disappeared from the traditional food and medicinal system, which may be attributed to the invasion of the food market and the prevalence of allopathic medicine. However, knowledge of these wild plants is still alive in memory, and women are the main holders of cultural knowledge as they use it to manage the cooking and processing of WFPs. Therefore, in this context, we strongly recommend the preservation of local biocultural heritage, promoted through future development and educational programs, which could represent a timely response to the loss of cultural and traditional knowledge.
21
Hoffmeister, Ellen. "Whole-Food, Plant-Based Diet May Alleviate Osteoarthritis Symptoms." Lippincottʼs Bone and Joint Newsletter 21, no. 7 (2015): 73–77. http://dx.doi.org/10.1097/01.bonej.0000469142.83530.d2.
Full text
22
Manley-Casco, Dario, and Paul Berkowitz. "A Whole Food Plant-Based Diet With a Novel Potassium-Binding Resin in a Patient With Advanced Chronic Kidney Disease." American Journal of Lifestyle Medicine 14, no. 6 (August 29, 2020): 592–94. http://dx.doi.org/10.1177/1559827620951036.
Full textAbstract:
Chronic kidney disease (CKD) is a major health problem with substantial morbidity and mortality. Plant-based diets decrease the incidence of CKD and progression of kidney disease and help prevent and treat the important comorbidities of obesity, type 2 diabetes, hypertension, and cardiovascular disease. However, in patients with CKD, there is concern that a plant-based diet may contribute to life-threatening hyperkalemia. We present a patient with CKD secondary to hypertensive glomerulosclerosis that worsened despite standard of care treatment. Shared decision making was used to initiate a whole food plant-based diet along with a potassium-binding resin (Patiromer) to control the potassium levels. The patient was able to be maintained on the whole food plant-based diet and an angiotensin-converting enzyme inhibitor without the development of hyperkalemia. This case shows that patients with CKD may be able to enjoy the benefits of a whole food plant-based diet while decreasing the risk of hyperkalemia by using the new potassium binders.
23
Lassen, Anne D., Lene M. Christensen, and Ellen Trolle. "Development of a Danish Adapted Healthy Plant-Based Diet Based on the EAT-Lancet Reference Diet." Nutrients 12, no. 3 (March 11, 2020): 738. http://dx.doi.org/10.3390/nu12030738.
Full textAbstract:
Plant-based diets have been linked to both health benefits and a lower climate impact. However, plant-based diets may represent both healthy and unhealthy dietary practices. The present study aimed to develop a nationally adapted healthy plant-based diet based on the global EAT-Lancet reference diet. Development took place in a series of steps. First, the original EAT-Lancet reference diet was evaluated based on food availability, i.e., using Danish food data (Model 1). Then, the model was further modified to reflect national food based dietary guidelines (FBDG) and characteristics of current consumption pattern, e.g., by including processed food, discretionary foods and beverages in the diet (Model 2). The contents of macronutrients, vitamins and minerals, except for vitamin D and iodine, were found to be sufficient for Model 2, according to the recommended nutrient density to be used for planning diets for groups of individuals aged 6–65 years. In addition, the study gave an insight into the nutrients and foods to be aware of in planning a predominantly plant-based diet, thereby providing directions for future revisions of sustainable FBDGs. These include a stronger emphasis on the intake of legumes, nuts and seeds, fruit and vegetables including dark green vegetables, whole-grain products and vegetable oils as well as lowering meat intake.
24
Greger, Michael. "A Whole Food Plant-Based Diet Is Effective for Weight Loss: The Evidence." American Journal of Lifestyle Medicine 14, no. 5 (April 3, 2020): 500–510. http://dx.doi.org/10.1177/1559827620912400.
Full textAbstract:
What does the best available balance of scientific evidence show is the optimum way to lose weight? Calorie density, water content, protein source, and other components significantly influence the effectiveness of different dietary regimes for weight loss. By “walling off your calories,” preferentially deriving your macronutrients from structurally intact plant foods, some calories remain trapped within indigestible cell walls, which then blunts the glycemic impact, activates the ileal brake, and delivers prebiotics to the gut microbiome. This may help explain why the current evidence indicates that a whole food, plant-based diet achieves greater weight loss compared with other dietary interventions that do not restrict calories or mandate exercise. So, the most effective diet for weight loss appears to be the only diet shown to reverse heart disease in the majority of patients. Plant-based diets have also been found to help treat, arrest, and reverse other leading chronic diseases such as type 2 diabetes and hypertension, whereas low-carbohydrate diets have been found to impair artery function and worsen heart disease, the leading killer of men and women in the United States. A diet centered on whole plant foods appears to be a safe, simple, sustainable solution to the obesity epidemic.
25
Massera, Daniele, Tarique Zaman, Grace E. Farren, and Robert J. Ostfeld. "A Whole-Food Plant-Based Diet Reversed Angina without Medications or Procedures." Case Reports in Cardiology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/978906.
Full textAbstract:
A 60-year-old man presented with typical angina and had a positive stress test. He declined both drug therapy and invasive testing. Instead, he chose to adopt a whole-food plant-based diet, which consisted primarily of vegetables, fruits, whole grains, potatoes, beans, legumes, and nuts. His symptoms improved rapidly, as well as his weight, blood pressure, and cholesterol levels. Plant-based diets have been associated with improved plasma lipids, diabetes control, coronary artery disease and with a reduction in mortality. Adoption of this form of lifestyle therapy should be among the first recommendations for patients with atherosclerosis.
26
Zaki, Timothy A., Gaurav Sharma, Lilian M. Correa, Krisann Polito-Moller, Sapana Shah, Shivam Joshi, Michelle M. McMacken, and Andrew M. Freeman. "Treatment of Type 2 Diabetes Mellitus with a Whole-Food, Plant-Based Diet." International Journal of Disease Reversal and Prevention 2, no. 1 (March 4, 2020): 6. http://dx.doi.org/10.22230/ijdrp.2020v2n1a117.
Full textAbstract:
We report the case of a 41-year-old male with severe obesity, hypertension, and an 8-year history of type 2 diabetes mellitus who achieved dramatic glycemic improvement following a 10-week low-fat, whole-food, plant based diet. Improvements in weight, blood pressure, and lipid values were noted as well.
27
Rivers, Desiree, Kay Umeakunne, Muhammad Mubasher, Brian Rivers, and Tiffany Carson. "Abstract C099: Examining the role of a whole food, plant-based diet on the gut microbiome, intramuscular fat, adiposity and risk for breast cancer in obese, post-menopausal African American women." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (January 1, 2023): C099. http://dx.doi.org/10.1158/1538-7755.disp22-c099.
Full textAbstract:
Abstract Background: Obese postmenopausal African American (AA) women are at increased risk of breast cancer. Obesity and aging have been associated with changes in the gut microbiota. Plant-based diets, such as soy isoflavone consumption may protect against breast cancer development. Methods: Participant inclusion and exclusion criteria informed active recruitment and sampling methods for study participants. A mixed-methods, lifestyle study was conducted to evaluate adoption of a culturally tailored, whole food, plant-based diet and changes in risk for breast cancer among obese, post-menopausal African American women. In the qualitative phase, we examined acceptability and feasibility of adopting a whole-food, plant-based diet. In the clinical research, we examined the effect of the whole food, plant-based diet on reductions in weight, adiposity, inflammation, circulating estrogen, and gut microbiome profile. Results: In five focus group discussions, 20 African American women described their knowledge of breast cancer risk factors, attitude toward a plant-based diet, experience with making lifestyle changes, and preferences for plant-based alternatives to traditional meat-based meals. Twelve African American women completed the 4-week whole food, plant-based diet feeding study, regular DEXA body composition scans, and provided blood and stool samples analyses. Women in the qualitative phase, reported being pleased with the whole-food, plant-based selections; document adherence to the meals with food tracking; and experience an average of a five pound weight loss. Biomarker examination is underway. Conclusion: This study addresses knowledge gaps in breast cancer risk and behavioral modifications affecting risk among an aging, obese, post-menopausal African American female population. Discussion will be provided describing how the outcomes of adiposity, inflammation, circulating estrogen, and gut microbiome profile are measured. As well, explanation of the relationship between these mechanistic outcomes will be explored. Lessons learned and insight regarding attrition and the number of women who dropped out or declined to participate will be shared. The long-term goal of this program of research will shed light on the mechanisms involved in the gut microbiome, tissue integrity and function with aging, and the contributions of changes to these systems on declining health and function in obese, postmenopausal African American women at risk for breast cancer. Citation Format: Desiree Rivers, Kay Umeakunne, Muhammad Mubasher, Brian Rivers, Tiffany Carson. Examining the role of a whole food, plant-based diet on the gut microbiome, intramuscular fat, adiposity and risk for breast cancer in obese, post-menopausal African American women [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr C099.
28
Campbell, Thomas M., and Scott E. Liebman. "Plant-based dietary approach to stage 3 chronic kidney disease with hyperphosphataemia." BMJ Case Reports 12, no. 12 (December 2019): e232080. http://dx.doi.org/10.1136/bcr-2019-232080.
Full textAbstract:
A 69-year-old man with type 2 diabetes, hypertension and stage 3 chronic kidney disease (CKD), hyperphosphataemia and borderline hyperkalaemia presented to an office visit interested in changing his diet to improve his medical conditions. He adopted a strict whole-foods, plant-based diet, without calorie or portion restriction or mandated exercise, and rapidly reduced his insulin requirements by >50%, and subsequently saw improvements in weight, blood pressure and cholesterol. His estimated glomerular filtration rate (eGFR) increased from 45 to 74 mL/min after 4.5 months on the diet and his microalbumin/creatinine ratio decreased from 414.3 to 26.8 mg/g. His phosphorus level returned to the normal range. For individuals with CKD, especially those with obesity, hypertension, or diabetes, a strict, ad libitum whole-food, plant-based diet may confer significant benefit, although one must consider potential limitations of a creatinine-based GFR equation in the face of significant weight loss.
29
Chuter, Robyn. "Reversal of Gestational Diabetes with a Low-Fat, Wholefood Plant-Based Diet." International Journal of Disease Reversal and Prevention 2, no. 2 (June 10, 2020): 7. http://dx.doi.org/10.22230/ijdrp.2020v2n2a177.
Full textAbstract:
Gestational diabetes mellitus (GDM) is a pathological disturbance in blood glucose regulation that is first detected during pregnancy. Pregnancy hormones, especially human placental lactogen, induce insulin resistance. a low-fat, whole-food, plant-based diet has been found to improve insulin sensitivity in prediabetes and type 1 and type 2 diabetes. Brooke was diagnosed with GDM despite having been on a 100% plantbased diet for 6 years prior to becoming pregnant; however, her diet was relatively high in fat. Within 10 days of reducing her fat intake to < 10% of daily energy, she achieved normal blood glucose readings.
30
Soto-Aguilar, Francisca, Javier Webar, and Ismael Palacios. "Whole food plant based diet: its mechanisms for the prevention and treatment of obesity." Revista de la Facultad de Medicina Humana 22, no. 1 (December 31, 2021): 162–70. http://dx.doi.org/10.25176/rfmh.v22i1.3616.
Full textAbstract:
Obesity is a metabolic condition with a continuous increasing rate, being considered today a “pandemic”. Due to this and the vast number of diseases it is associated with, there is a need for a treatment of this condition that is both effective and healthy in a comprehensive way. In this context, the concepts of lifestyle medicine and plant-based diets have emerged in medicine and in scientific research, and the latter have demonstrated benefits in all these areas and are being part of several scientific association’s recommendations today. In this article, a plant-based diet is briefly defined, and the mechanisms by which this type of diet provides benefits for the control of body weight are explored, including the satiety it generates and its characteristic low caloric density, the higher thermic effect of foods, the positive modulation of the gut microbiota, its effects on the insulin sensitivity, the absence of animal protein and how this affects the body weight, and the effects it has on the leptin hormone. Plant-based diets has been studied both in observational and interventional studies and positioned as a great alternative for the prevention and treatment of obesity, in addition to being a safe and health dietary pattern. We hope that in the future, more health professionals consider this evidence and incorporate it as part of their therapeutic tools.
31
Liu, Yuan. "Potential Application of Mediterranean Diet and DASH Diet and Plant-Based Diet in Solving the Problem of Hypertension in Women." Highlights in Science, Engineering and Technology 109 (July 24, 2024): 127–32. http://dx.doi.org/10.54097/f212pd59.
Full textAbstract:
The food industry is thriving due to economic prosperity. People's food requirements have expanded beyond mere sustenance to include a desire for diversity. However, long-term pressure from heavy work or family responsibilities may cause women to develop irregular dietary habits, leading to obesity and related health issues. As hypertension is a significant contributor to cardiovascular disease, this paper compares the advantages and disadvantages of three popular diets: the Mediterranean diet, the DASH diet, and the plant- based diet. The paper discusses the pros and cons of each diet to determine which one is more suitable for the female to prevent and alleviate hypertension symptoms. By comparing the regional, quantitative, nutritional value and public acceptance of three different diets, it is concluded that the plant-based diet which consists of fruits and vegetables in addition to nuts, seeds, whole grains, and legumes, is more suitable as a daily diet for women to alleviate hypertension symptoms.
32
Isaacs, Sydeena, Marisa Howell, Melinda Bogardus, Martie Thompson, and Shenghui Wu. "Development of a Theory-Based Three-week Whole-Food Plant-Based Diet Intervention for College Students." Journal of Nutrition Education and Behavior 55, no. 7 (July 2023): 68–69. http://dx.doi.org/10.1016/j.jneb.2023.05.151.
Full text
33
Päivärinta, Essi, Suvi T. Itkonen, Tiina Pellinen, Mikko Lehtovirta, Maijaliisa Erkkola, and Anne-Maria Pajari. "Replacing Animal-Based Proteins with Plant-Based Proteins Changes the Composition of a Whole Nordic Diet—A Randomised Clinical Trial in Healthy Finnish Adults." Nutrients 12, no. 4 (March 28, 2020): 943. http://dx.doi.org/10.3390/nu12040943.
Full textAbstract:
Increased consumption of plant-based foods and decreased consumption of animal-based foods is recommended for healthy diets and sustainable food production. We investigated the effects of partial replacement of dietary animal proteins with plant-based ones on intake of energy-yielding nutrients, fibre, and plasma lipoproteins. This 12-week randomised clinical intervention comprised 107 women and 29 men (20–69 years) in three diet groups with different dietary protein compositions (“ANIMAL”: Animal 70%/plant 30%; “50/50”: Animal 50%/plant 50%; “PLANT”: Animal 30%/plant 70%; all: Protein intake 17 E%). Nutrient intakes were assessed by 4-day food records. Saturated fat intake (E%) was lower and polyunsaturated fatty acid intake (E%) higher in the PLANT and 50/50 groups compared to the ANIMAL group (p < 0.001 for all). Fibre intake was higher in the PLANT (p ˂ 0.001) and 50/50 (p = 0.012) groups. Total and LDL cholesterol were lower in the PLANT than in the ANIMAL group (p = 0.003 for both) but no differences in HDL cholesterol or triglycerides were observed (p > 0.05). Replacing animal protein with plant protein sources in the diet led to an increased fibre intake and improved dietary fat quality as well as blood lipoprotein profile. Flexitarian diets could provide healthy and more sustainable alternatives for the current, predominantly animal-based diets.
34
Lin, Annie, Adrian Cornely, Faiza Kalam, Sougata Sen, Jennifer Makelarski, Christopher Colvin, Danielle Ward, and Grace Mirsky. "Prediction of Diet Quality Based on Day-Level Meal Pattern: A Preliminary Analysis Using Decision Tree Modeling." Current Developments in Nutrition 6, Supplement_1 (June 2022): 417. http://dx.doi.org/10.1093/cdn/nzac055.006.
Full textAbstract:
Abstract Objectives Previous studies have investigated if meal timing is associated with energy and macronutrient intake. However, few focus on the combination of food intake and meal timing and their association with diet quality. We use machine learning to examine how day-level meal patterns (food group intake, meal timing) predict diet quality among adults. Methods We analyzed diet data from interviewer-administered 24-hour recalls from the NHANES 2015–2016 and 2017–2018 cycles (N = 9761). Fifteen food groups were examined: fruit, fruit juice, vegetables, whole grains, meats (red, cured, poultry, seafood), eggs, plant protein, dairy, oils, solid fats, added sugar, and alcohol. Proportion of intake for each food group per participant - relative to that participant's total daily intake of that food group - was included as input parameters for each meal (breakfast, lunch, dinner). Diet quality was computed using the Healthy Eating Index 2015 (HEI-2015); higher scores represented better diet quality. Cutoff threshold for a higher vs. lower quality diet was defined by the 75th percentile of HEI-2015 for the dataset (cutoff = 59.24). Decision tree modeling identified the inputs that contributed to the highest information gain and the optimal classification threshold for each input. Results On average, participants consumed 0.4 ± 0.8 cup equivalents of fruits and 0.6 ± 1.2 ounce equivalents of whole grains. These two food groups contributed most to the diet quality prediction model, which had a 78% classification accuracy for the dataset. Lower quality diets were associated with: a) < 2% of both total fruit and whole grain intake at breakfast; b) >2% of total fruit but < 2% of total whole grain intake at breakfast; or c) >2% of total whole grain intake at breakfast but < 2% of total fruit intake at breakfast and lunch. Higher quality diets were associated with: a) >2% of both total fruit and whole grain intake at breakfast or b) < 2% of total fruit intake at breakfast but > 2% of both total whole grain intake at breakfast and fruit intake at lunch. Food group intake at dinner was not a top predictor in the preliminary model. Conclusions Preliminary analyses revealed that the timing of fruit and whole grain consumption are important predictors of diet quality. Future studies should test the preliminary model on additional datasets and should include snacking episodes in the analyses. Funding Sources None.
35
Trautwein, Elke A., and Sue McKay. "The Role of Specific Components of a Plant-Based Diet in Management of Dyslipidemia and the Impact on Cardiovascular Risk." Nutrients 12, no. 9 (September 1, 2020): 2671. http://dx.doi.org/10.3390/nu12092671.
Full textAbstract:
Convincing evidence supports the intake of specific food components, food groups, or whole dietary patterns to positively influence dyslipidemia and to lower risk of cardiovascular diseases (CVD). Specific macro- and micro-components of a predominantly plant-based dietary pattern are vegetable fats, dietary fibers, and phytonutrients such as phytosterols. This review summarizes the current knowledge regarding effects of these components on lowering blood lipids, i.e., low-density lipoprotein cholesterol (LDL-C) and on reducing CVD risk. The beneficial role of a plant-based diet on cardiovascular (CV) health has increasingly been recognized. Plant-based dietary patterns include a Mediterranean and Nordic diet pattern, the dietary approaches to stop hypertension (DASH), and Portfolio diet, as well as vegetarian- or vegan-type diet patterns. These diets have all been found to lower CVD-related risk factors like blood LDL-C, and observational study evidence supports their role in lowering CVD risk. These diet patterns are not only beneficial for dyslipidemia management and prevention of CVD but further contribute to reducing the impact of food choices on environmental degradation. Hence, the CV health benefits of a predominantly plant-based diet as a healthy and environmentally sustainable eating pattern are today recommended by many food-based dietary as well as clinical practice guidelines.
36
Jakše, Boštjan, Uroš Godnov, Zlatko Fras, and Nataša Fidler Mis. "Associations of Dietary Intake with Cardiovascular Risk in Long-Term “Plant-Based Eaters”: A Secondary Analysis of a Cross-Sectional Study." Nutrients 16, no. 6 (March 11, 2024): 796. http://dx.doi.org/10.3390/nu16060796.
Full textAbstract:
A plant-based diet rich in whole foods and fiber is beneficial for cardiovascular (CV) health. This impact is often linked to specific food groups and their preparation methods, reflecting the overall dietary pattern. However, research on the long-term effects of a carefully designed plant-based diet on adults transitioning from a typical Western lifestyle is limited. Notably, studies on people managing CV risk factors effectively are scarce. As part of a cross-sectional study, we examined 151 individuals committed to a long-term, well-designed plant-based diet and active lifestyle. We investigated how specific food groups and macronutrient intake are related to various CV health markers. In this secondary analysis, our comprehensive approach encompassed several methods: 3-day weighted dietary records, fasting blood lipid and blood pressure measurements, body composition assessments, and evaluations of lifestyle status. We adjusted our analysis for multiple variables, such as age, sex, current body mass index, smoking status, physical activity, and time (years) following the plant-based diet. Our findings revealed several associations between macronutrient intake (per 50 g) and CV risk markers, although these associations were generally weak. Individuals who consumed more whole grains and fruits had lower levels of total, low-density lipoprotein (LDL-C), and high-density lipoprotein (HDL-C) cholesterol. We also found associations between the intake of legumes and nuts/seeds and reduced HDL-C levels. These findings suggested that these food groups might influence the lipid profile, contributing to CV health in a plant-based diet. A greater intake of spices/herbs was associated with lower uric acid levels, while diets rich in plant-based fast food and pasta (made from white flour) were associated with higher uric acid levels. A greater intake of various macronutrients, such as fiber, carbohydrates (from whole-food sources), proteins, and different types of fats (saturated fatty acids [SFAs], monounsaturated fatty acids [MUFAs], and polyunsaturated fatty acids [PUFAs]), was associated with lower levels of total cholesterol, LDL-C (only for carbohydrates), and HDL-C. We found a unique negative correlation between PUFA intake and LDL-C, suggesting that PUFAs might significantly affect LDL-C levels. In contrast, increased fiber, protein and SFA consumption were associated with increased uric acid levels. These findings support the impact of dietary patterns on CV risk factors, highlighting that even small amounts of unhealthy food groups can significantly influence specific CV risk markers, regardless of the overall diet.
37
Liebman, Scott E., and Shivam Joshi. "Plant-Based Diets and Peritoneal Dialysis: A Review." Nutrients 14, no. 6 (March 19, 2022): 1304. http://dx.doi.org/10.3390/nu14061304.
Full textAbstract:
Whole food plant-based diets are gaining popularity as a preventative and therapeutic modality for numerous chronic health conditions, including chronic kidney disease, but their role and safety in end-stage kidney disease patients on peritoneal dialysis (PD) is unclear. Given the general public’s increased interest in this dietary pattern, it is likely that clinicians will encounter individuals on PD who are either consuming, considering, or interested in learning more about a diet with more plants. This review explores how increasing plant consumption might affect those on PD, encompassing potential benefits, including some specific to the PD population, and potential concerns.
38
Rivers, Desiree A., Regina Leonis, Zakirah A. Abdul-Hameed, Shaliesh A. Singh, and Brian A. Rivers. "Abstract B100: Using a plant-based diet and exercise to improve outcomes in African American postmenopausal breast and endometrial cancer survivors." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (December 1, 2023): B100. http://dx.doi.org/10.1158/1538-7755.disp23-b100.
Full textAbstract:
Abstract Background: Obese postmenopausal African American (AA) women with breast and endometrial cancer are at increased risk of recurrence. Obesity and aging have been associated with changes in the gut microbiota. Plant-based diets, such as soy isoflavone consumption may protect against breast and endometrial cancer. Methods: A mixed-methods, lifestyle intervention study was conducted to evaluate adoption of a whole-food plant-based diet, physical activity, and changes in risk for breast and endometrial cancer among obese, post-menopausal AA women. We examined acceptability and feasibility of adopting a whole-food, plant-based diet and the effect of the diet on reductions in weight, adiposity, inflammation, circulating estrogen, and gut microbiome profile. Results: In 5 focus group discussions, 20 AA women described their knowledge of breast and endometrial cancer risk factors, attitude toward a plant-based diet, experience with making lifestyle changes, and preferences for plant-based alternatives to traditional meat-based meals. This feedback was used to tailor the 4-weeks of plant-based produce boxes provided to the women. Women report being pleased with the food selections; document adherence to the meals and physical activity with food and exercise tracking. Gut microbiome analysis is underway. Conclusion: This study addresses knowledge gaps in breast and endometrial cancer risk and behavioral modifications affecting risk among an obese, post-menopausal AA female population. The long-term goal of this program of research will shed light on the mechanisms involved in the gut microbiome and the contributions of changes to these systems on declining health. Citation Format: Desiree A. Rivers, Regina Leonis, Zakirah A. Abdul-Hameed, Shaliesh A. Singh, Brian A. Rivers. Using a plant-based diet and exercise to improve outcomes in African American postmenopausal breast and endometrial cancer survivors [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr B100.
39
Plotnikoff, Gregory A., Linda Dobberstein, and Susan Raatz. "Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions." Nutrients 15, no. 6 (March 13, 2023): 1387. http://dx.doi.org/10.3390/nu15061387.
Full textAbstract:
Plant-based diets, both vegan and vegetarian, which emphasize grains, vegetables, fruits, legumes, nuts, and seeds are increasingly popular for health as well as financial, ethical, and religious reasons. The medical literature clearly demonstrates that whole food plant-based diets can be both nutritionally sufficient and medically beneficial. However, any person on an intentionally restrictive, but poorly-designed diet may predispose themselves to clinically-relevant nutritional deficiencies. For persons on a poorly-designed plant-based diet, deficiencies are possible in both macronutrients (protein, essential fatty acids) and micronutrients (vitamin B12, iron, calcium, zinc, and vitamin D). Practitioner evaluation of symptomatic patients on a plant-based diet requires special consideration of seven key nutrient concerns for plant-based diets. This article translates these concerns into seven practical questions that all practitioners can introduce into their patient assessments and clinical reasoning. Ideally, persons on plant-based diets should be able to answer these seven questions. Each serves as a heuristic prompt for both clinician and patient attentiveness to a complete diet. As such, these seven questions support increased patient nutrition knowledge and practitioner capacity to counsel, refer, and appropriately focus clinical resources.
40
Rajaram, Sujatha, Julie Jones, and Grace J. Lee. "Plant-Based Dietary Patterns, Plant Foods, and Age-Related Cognitive Decline." Advances in Nutrition 10, Supplement_4 (November 1, 2019): S422—S436. http://dx.doi.org/10.1093/advances/nmz081.
Full textAbstract:
ABSTRACT The aging population is expanding, as is the prevalence of age-related cognitive decline (ARCD). Of the several risk factors that predict the onset and progression of ARCD, 2 important modifiable risk factors are diet and physical activity. Dietary patterns that emphasize plant foods can exert neuroprotective effects. In this comprehensive review, we examine studies in humans of plant-based dietary patterns and polyphenol-rich plant foods and their role in either preventing ARCD and/or improving cognitive function. As yet, there is no direct evidence to support the benefits of a vegetarian diet in preventing cognitive decline. However, there is emerging evidence for brain-health–promoting effects of several plant foods rich in polyphenols, anti-inflammatory dietary patterns, and plant-based dietary patterns such as the Mediterranean diet that include a variety of fruits, vegetables, legumes, nuts, and whole grains. The bioactive compounds present in these dietary patterns include antioxidant vitamins, polyphenols, other phytochemicals, and unsaturated fatty acids. In animal models these nutrients and non-nutrients have been shown to enhance neurogenesis, synaptic plasticity, and neuronal survival by reducing oxidative stress and neuroinflammation. In this review, we summarize the mounting evidence in favor of plant-centered dietary patterns, inclusive of polyphenol-rich foods for cognitive well-being. Randomized clinical trials support the role of plant foods (citrus fruits, grapes, berries, cocoa, nuts, green tea, and coffee) in improving specific domains of cognition, most notably frontal executive function. We also identify knowledge gaps and recommend future studies to identify whether plant-exclusive diets have an added cognitive advantage compared with plant-centered diets with fish and/or small amounts of animal foods.
41
Valdez, Elizabeth Salerno, Heidi Pottinger, Angela Urbon-Bonine, and Burris Duncan. "Feasibility of engaging college students in a 10-day plant-based diet." Health Education Journal 77, no. 8 (July 6, 2018): 952–63. http://dx.doi.org/10.1177/0017896918785933.
Full textAbstract:
Objective: This study sought to determine the feasibility of (a) engaging college students in experiential learning through a 10-day whole foods plant-based diet intervention, (b) bringing pertinence to the course topics that had an emphasis on chronic conditions and (c) understanding how the intervention influenced students’ perceptions and behaviours. Design: Quasi-experimental design. Biomarkers, dietary perceptions and behaviours were collected at baseline and 11-day post-intervention. Setting: The study was implemented in the context of an undergraduate/graduate public health course. Method: We assessed the feasibility of the intervention using an acceptability focus, including participant retention in the intervention, and participant self-reported experience with the plant-based diet. We also utilised an implementation research focus, concerning the extent, likelihood and manner in which an intervention can be fully implemented as planned and proposed. Results: The intervention was determined to be feasible. Participants learned that their diet can affect multiple health conditions and all changed their diet in some way or another as a result. Of the 10 participants, mean change in total cholesterol was −26 mg/dL, high-density lipoprotein (HDL) cholesterol was −6.1 mg/dL and low-density lipoprotein (LDL) cholesterol was −21.6 mg/dL, all with p values <.05. Conclusion: Findings suggest that through experiential learning, students will consider a whole food plant-based diet and/or make some personal lifestyle changes as a result.
42
Gibbs, Joshua, and Francesco P. Cappuccio. "Plant-Based Dietary Patterns for Human and Planetary Health." Nutrients 14, no. 8 (April 13, 2022): 1614. http://dx.doi.org/10.3390/nu14081614.
Full textAbstract:
The coronavirus pandemic has acted as a reset on global economies, providing us with the opportunity to build back greener and ensure global warming does not surpass 1.5 °C. It is time for developed nations to commit to red meat reduction targets and shift to plant-based dietary patterns. Transitioning to plant-based diets (PBDs) has the potential to reduce diet-related land use by 76%, diet-related greenhouse gas emissions by 49%, eutrophication by 49%, and green and blue water use by 21% and 14%, respectively, whilst garnering substantial health co-benefits. An extensive body of data from prospective cohort studies and controlled trials supports the implementation of PBDs for obesity and chronic disease prevention. The consumption of diets high in fruits, vegetables, legumes, whole grains, nuts, fish, and unsaturated vegetable oils, and low in animal products, refined grains, and added sugars are associated with a lower risk of all-cause mortality. Meat appreciation, health concerns, convenience, and expense are prominent barriers to PBDs. Strategic policy action is required to overcome these barriers and promote the implementation of healthy and sustainable PBDs.
43
Miller, Melissa Farmer, Zhongyu Li, and Melissa Habedank. "A Randomized Controlled Trial Testing the Effectiveness of Coping with Cancer in the Kitchen, a Nutrition Education Program for Cancer Survivors." Nutrients 12, no. 10 (October 15, 2020): 3144. http://dx.doi.org/10.3390/nu12103144.
Full textAbstract:
Following a diet rich in whole grains, vegetables, fruit, and beans may reduce cancer incidence and mortality. The aim of this study was to investigate the effect of Coping with Cancer in the Kitchen (CCK), an 8 week in-person program offering education, culinary demonstrations and food tasting, and psychosocial group support, compared to receiving CCK printed materials by mail on knowledge, confidence, and skills in implementing a plant-based diet. A total of 54 adult cancer survivors were randomly assigned to intervention (n = 26) and control groups (n = 27) with assessments at baseline, 9, and 15 weeks via self-administered survey. The response rate was 91% at 9 weeks and 58% at 15 weeks. The majority of our study participants were female breast cancer survivors (58%) who had overweight or obesity (65%). Compared with the control, there were significant (p < 0.05) increases in intervention participants’ knowledge about a plant-based diet at weeks 9 and 15, reductions in perceived barriers to eating more fruits and vegetables at week 9, and enhanced confidence and skills in preparing a plant-based diet at week 15. There was a significant reduction in processed meat intake but changes in other food groups and psychosocial measures were modest. Participation in CCK in person increased knowledge, skills, and confidence and reduced barriers to adopting a plant-based diet. Positive trends in intake of plant-based foods and quality of life warrant further investigation in larger-scale studies and diverse populations.
44
Estell, Madeline, Jaimee Hughes, and Sara Grafenauer. "Plant Protein and Plant-Based Meat Alternatives: Consumer and Nutrition Professional Attitudes and Perceptions." Sustainability 13, no. 3 (February 1, 2021): 1478. http://dx.doi.org/10.3390/su13031478.
Full textAbstract:
Plant-based and flexitarian eating patterns are increasingly popular, and the food supply system has responded with a wide range of convenience products despite a lack of understanding regarding consumer views. The aim of this study was to explore consumer and nutrition professional (NP) perceptions and attitudes to plant protein, including plant-based meat alternatives (PBMA) within an Australian context. Using an online survey promoted via social media, 679 responses (89% completion rate), achieved an even spread across key age groups. A total of sixty percent reported following a special diet, with 25% vegan and 19% flexitarian. ‘Health’ was a key driver for diet type among the NPs (53.3%) and they were less likely to follow a special diet, while “ethical” reasons were cited by consumers (69%). Plant-based eating was considered a vegan dietary pattern and the most frequently consumed plant-based proteins were whole grains. Most (74%) had tried PBMA, but they were more frequently chosen by consumers, with burger patties then sausages and mince selected as a ‘trendy’ choice; taste was very important across both groups. Products mimicking chicken and fish were of less interest. Plant-based claims were observed by 78% but these were also of greater interest to consumers. Participants reported looking for whole ingredients and iron content and expected that both iron and vitamin B12 would be comparable to red meat. Sodium was the nutrient of greatest interest to NPs and, together, these results help inform the direction for product innovation, while also highlighting the need to assess the adequacy of the dietary pattern when promoting sustainable plant-based eating.
45
Campbell, Erin K., Mohammad Fidahusain, and Thomas M. Campbell II. "Evaluation of an Eight-Week Whole-Food Plant-Based Lifestyle Modification Program." Nutrients 11, no. 9 (September 3, 2019): 2068. http://dx.doi.org/10.3390/nu11092068.
Full textAbstract:
Poor diet quality is the leading cause of death both in the United States and worldwide, and the prevalence of obesity is at an all-time high and is projected to significantly worsen. Results from an eight-week group program utilizing an ad-libitum whole-food plant-based dietary pattern, were reviewed. There were 79 participants, all self-referred from the community, including 24 (30.4%) who were already vegetarian or vegan at baseline. Seventy-eight participants (98.7%) completed the eight-week program. Among completers, those with higher BMI at baseline lost a larger percentage of their body weight (total body weight loss of 3.0 ± SD 2.1%, 5.8 ± 2.8%, and 6.4 ± 2.5% for participants who had baseline BMI in normal, overweight, and obese range, respectively). The average weight loss for all the completers was 5.5 ± 3.0 kg (p < 0.0001). Final blood pressure and plasma lipids were reduced compared to baseline (SBP decreased 7.1 ± 15.5 mmHg (p = 0.0002), DBP decreased 7.3 ± 10.9 mmHg (p < 0.0001), total cholesterol decreased 25.2 ± 24.7 mg/dL (p < 0.0001), LDL decreased 15.3 ± 21.1 mg/dL (p < 0.0001)). Twenty-one (26.9%) participants were able to decrease or stop at least one chronic medication compared to two (2.6%) participants who required an increased dose of a chronic medication. Participants who were already vegetarian or vegan at baseline experienced statistically significant weight loss and reductions in total and LDL cholesterol. There was a non-significant trend toward less weight loss in these participants compared to participants who were non-vegetarian at baseline. Reductions in total and LDL cholesterol were not significantly different when comparing vegetarian or vegan and non-vegetarian participants. A whole-food plant-based dietary intervention may provide significant short-term benefits for both non-vegetarian, vegetarian, and vegan individuals.
46
Behisht, Nujba, and Navaneetha R. "Impact of Plant- Based Diet in Prevention of Non-Communicable Diseases." International Journal for Research in Applied Science and Engineering Technology 10, no. 7 (July 31, 2022): 1015–19. http://dx.doi.org/10.22214/ijraset.2022.45428.
Full textAbstract:
Abstract: Plant-Based diet includes fruits , vegetables, nuts, seeds, oils, whole grains, legumes, and beans. A vegan diet excludes all animal products. A plant-based diet provides necessary proteins, fats, carbohydrates, vitamins , minerals as well as abundant fibre and phytonutrients required for optimal health, Essential nutrients present in plant diet helps to alleviate inflammation in our bodies. The covid pandemic has prompted many people to switch to a more organic, plant-based diet that includes nutraceuticals or supplements. This trend is gaining popularity globally. A literature search of plant based protein, food sources, nutritional composition and health benefits, effect on cardiovascular risk, insulin resistance, benefits of plant protein intake vs animal protein in the prevention and management of cancer , effect of vegan diet on coronary heart disease was carried out. As per the literature, studies were conducted on functional and bioactive properties of soy protein in terms of reducing disorder risk, modulating inflammation and their systemic effects. Dual X-ray Absorptiometry assessed body composition, Homeostasis Model Assessment (HOMA-IR) assessed insulin resistance, and a linear regression model was used to find out effect of plant based diets on weight loss. Using a data from Nurses Health Study 2, substituting 5% energy intake from vegetarian protein for animal protein was associated with 23% lower risk of type-2 diabetes mellitus. The study involved a supervised resistance educational programme was conducted twice a week for 12 weeks to compare a vegan diet with omnivores diet. This review article gives an overview of plant based diet and emphasises the benefits of a plant based diet, and its impact on the body and mind
47
Isaacs, Sydeena, Melinda Bogardus, Alli Young, Martie Thompson, and Shenghui Wu. "Changes in Diet Quality and Adherence in College Students After a 3-Week Whole-Food Plant-Based Vegan Diet Intervention." Journal of Nutrition Education and Behavior 56, no. 8 (August 2024): S15—S16. http://dx.doi.org/10.1016/j.jneb.2024.05.037.
Full text
48
Ganguli, Subhas C., Lindsey A. Russell, and Keith S. Tsoi. "Implementation of a Whole Food Plant Based Diet in a Food as Prevention Program in a Resource Constrained Environment." Journal of Lifestyle Medicine 12, no. 3 (September 30, 2022): 148–52. http://dx.doi.org/10.15280/jlm.2022.12.3.148.
Full text
49
Appah, N. E., K. P. Adeosun, and B. T. Omonona. "Awareness and willingness to consume whole plant-based food in Ibadan North Local Government Area of Oyo State, Nigeria." Journal of Agriculture and Food Sciences 19, no. 2 (February 27, 2022): 75–85. http://dx.doi.org/10.4314/jafs.v19i2.8.
Full textAbstract:
Food is an essential entity that supports life and is required in the right quantity and quality in all living things which includes man and animals. Food contains nutrients which would be used in the body of an organism to sustain growth, aid vital processes and to furnish energy. Even though some foods are important for growth and development, the factors influencing households to purchase is yet unknown in the literature. More so, low consumption of plant based food can lead to poor nutrition which impairs daily health and wellbeing. Thus, this study examines factors that influencing the willingness to consume plant-based whole foods. Data were obtained from primary source from households in Ibadan, Oyo State through the use of structured questionnaire with the adoption of multistage sampling procedure. Data were analysed using the Descriptive Statistics, Ordinary Least Squares Regression Model, Logistic Regression, Probit Regression Model. The findings from the study show that marital status, educational level and household size are the important determinants of the level of awareness of whole plant-based diet by households. Likewise, results show that marital status, education and income are the variables that influence the willingness of households to consume whole plant food. The study concludes that the consumption of whole plant-based foods is of great benefit to households as the prevalence of non-communicable diseases would be drastically reduced. The study recommends that households should be educated on the benefits of whole plant food through focused group discussion and media channels to increase the willingness to consume it. Government should place taxes on highly processed food to discourage their purchase and consumption.
50
Hernáez, Álvaro, and Ramón Estruch. "The Mediterranean Diet and Cancer: What Do Human and Molecular Studies Have to Say about It?" Nutrients 11, no. 9 (September 9, 2019): 2155. http://dx.doi.org/10.3390/nu11092155.
Full textAbstract:
Mediterranean diet (MD) is a well-known healthy dietary pattern, linked to: (1) high intakes of olive oil as main the culinary fat, plant-based foods (fruits, vegetables, legumes, whole grains, tree nuts, and seeds), and fish; and (2) a moderate consumption of white meat, eggs, dairy products such as yogurt and cheese, and wine always with meals [...]