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&NA;. "WHO looks into QOL." Inpharma Weekly &NA;, no. 896 (July 1993): 9. http://dx.doi.org/10.2165/00128413-199308960-00017.
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Nwenyi, Emmanuel, Joan Leafman, Kathleen Mathieson, and Nkonye Ezeobah. "Differences in quality of life between pediatric sickle cell patients who used hydroxyurea and those who did not." International Journal of Health Care Quality Assurance 27, no. 6 (July 8, 2014): 468–81. http://dx.doi.org/10.1108/ijhcqa-01-2013-0008.
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Purpose – The purpose of this paper is to examine the differences in quality of life (QoL) between two groups of pediatric sickle cell patients: those who used hydroxyurea and those who chose not to use the medication to treat sickle cell disease. Design/methodology/approach – The study was a quantitative, non-randomized, cross-sectional, comparative study. In total, 100 children ages seven to 17 participated in the study. Parents of the patients completed a demographic questionnaire while the participants completed the Pediatric Quality of Life Inventory (Peds QoL) and Sickle Cell Disease Quality of Life Inventory (SCD QoL). Findings – The Ped QoL regression analysis revealed that hydroxyurea use and parental marital status accounted for a significant proportion of the variance in Ped QoL. The SCD QoL regression analysis also revealed that hydroxyurea and age accounted for a significant proportion of the variance in SCD QoL. Finally, the regression analysis revealed that SCD, parental marital status, parental income, sex, age, race and number of siblings did not account for a significant proportion of the variance in SCD crises per year. Originality/value – This paper proved a need to study the differences in QoL between those pediatric patients who used hydroxyurea and those who did not use the medication.
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Araújo, Hirla Vanessa Soares de, Thaisa Remigio Figueirêdo, Christefany Régia Braz Costa, Maria Mariana Barros Melo da Silveira, Rebeka Maria de Oliveira Belo, and Simone Maria Muniz da Silva Bezerra. "Quality of life of patients who undergone myocardial revascularization surgery." Revista Brasileira de Enfermagem 70, no. 2 (April 2017): 257–64. http://dx.doi.org/10.1590/0034-7167-2016-0201.
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ABSTRACT Objective: to evaluate the quality of life of patients who underwent revascularization surgery. Method: a descriptive, cross sectional study, with quantitative approach carried out with 75 patients. The questionnaire WHOQOL-Bref was used to evaluate the quality of life (QOL). Results: patients' QOL evaluation presented a moderate result, with need of improvement of all domains. Low income patients had the worst evaluation of QOL in the domain environment (p=0,021), and the ones from Recife/metropolitan area, in the domain social relationship (p=0,021). Smoker (p=0,047), diabetic (p=0,002) and alcohol consumption (p=0,035) patients presented the worst evaluation of the physical domain. Renal patients presented the worst evaluation of QOL in the physical (P=0,037), psychological (p=0,008), social relationship (p=0,006) domains and total score (p=0,009). Conclusion: the improvement of QOL depends on the individual's process of behavioral change and the participation of health professionals is essential to formulate strategies to approach these patients, especially concerning health education.
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Santos-García, D., T. de Deus Fonticoba, E. Suárez Castro, A. Aneiros Díaz, and D. McAfee. "5-2-1 Criteria: A Simple Screening Tool for Identifying Advanced PD Patients Who Need an Optimization of Parkinson’s Treatment." Parkinson's Disease 2020 (March 24, 2020): 1–6. http://dx.doi.org/10.1155/2020/7537924.
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Objective. 5- (5 times oral levodopa tablet taken/day) 2- (2 hours of OFF time/day) 1- (1 hour/day of troublesome dyskinesia) criteria have been proposed by a Delphi expert consensus panel for diagnosing advanced Parkinson’s disease (PD). The aim of the present study is to compare quality of life (QoL) in PD patients with “5-2-1 positive criteria” vs QoL in PD patients without “5-2-1 positive criteria” (defined as meeting ≥1 of the criteria). Methods. This is a cross-sectional, observational, monocenter study. Three different instruments were used to assess QoL: the 39-Item Parkinson’s Disease Quality of Life Questionnaire Summary Index Score (PDQ-39SI); a subjective rating of perceived QoL (PQ-10); and the EUROHIS-QOL 8-Item Index (EUROHIS-QOL8). Results. From a cohort of 102 PD patients (65.4 ± 8.2 years old, 53.9% males; disease duration 4.7 ± 4.5 years), 20 (19.6%) presented positive 5-2-1 criteria: 6.9% for 5, 17.6% for 2, and 4.9% for 1. 37.5% (12/32) and 25% (5/20) of patients with motor complications and dyskinesia, respectively, presented 5-2-1 negative criteria. Both health-related (PDQ-39SI, 25.6 ± 14 vs 12.1 ± 9.2; p<0.0001) and global QoL (PQ-10, 6.1 ± 2 vs 7.1 ± 1.3; p=0.007; EUROHIS-QOL8, 3.5 ± 0.5 vs 3.7 ± 0.4; p=0.034) were worse in patients with 5-2-1 positive criteria. Moreover, nonmotor symptoms burden (Non-Motor Symptoms Scale total score, 64.8 ± 44.8 vs 39.4 ± 35.1; p<0.0001) and autonomy for activities of daily living (ADLS scale, 73.5 ± 13.1 vs 89.2 ± 9.3; p<0.0001) were worse in patients with 5-2-1 positive criteria. Patient’s principal caregiver’s strain (Caregiver Stain Index, 4.3 ± 3 vs 1.5 ± 1.6; p<0.0001), burden (Zarit Caregiver Burden Inventory, 28.4 ± 12.5 vs 10.9 ± 9.8; p<0.0001), and mood (Beck Depression Inventory II, 12.2 ± 7.2 vs 6.2 ± 6.1; p<0.0001) were worse in patients with 5-2-1 positive criteria as well. Conclusions. QoL is worse in patients meeting ≥1 of the 5-2-1 criteria. This group of patients and their caregivers are more affected as a whole. These criteria could be useful for identifying patients in which it is necessary to optimize Parkinson’s treatment.
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Yuko Akagawa, Sachiko Makabe, Tomoko Ito, Yutaka Kimura, and Hideaki Andoh. "Challenge and hope for parents who have cancer." International Journal of Science and Research Archive 3, no. 1 (August 30, 2021): 136–47. http://dx.doi.org/10.30574/ijsra.2021.3.1.0125.
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Parents who have cancer face particular problems in their relationships with children. This study aims to clarify 1) the current status of challenge/hope in parental cancer, 2) the factors related to challenge/hope, and 3) the relationship between challenge/hope and QOL/stress-coping ability. Cross-sectional national survey was conducted at designated cancer hospitals in Japan. Participants were undergoing cancer treatment and have children under 18 years old. The questionnaire included demographic data, QOL, ability to cope with stress, and challenge/hope. From 11 hospitals, 54 patients (response rate: 79.4%) participated. Majority of participants were female (72.2%) with the mean age of 39.3 ± 5.3 (SD). The total score was QOL (FACT-G: 50.4 ± 16.2), stress-coping ability (SOC: 46.7 ± 10.4). The main challenges were an inability to fulfill the parental role and children’s mental suffering due to loneliness. The main aspects of hope were the value of the children’s present self, being a parent, and strengthening family bonds. Gender and disease duration were significantly related with challenge/hope. Challenge was significantly related with QOL/stress-coping ability. Parents who have cancer derive hope from their relationship with their children, although they feel a gap between their ideal role/value as a parent and their current status.
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Eapen, Valsamma, Rudi Črnčec, Amelia Walter, and Kwok Ping Tay. "Conceptualisation and Development of a Quality of Life Measure for Parents of Children with Autism Spectrum Disorder." Autism Research and Treatment 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/160783.
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Parents of children with autism spectrum disorder (ASD) tend to experience greater psychological distress than parents of typically developing children or children with other disabilities. Quality of Life (QoL) is increasingly recognised as a critical outcome measure for planning and treatment purposes in ASD. There is a need for ASD-specific QoL measures as generic measures may not capture all relevant aspects of living with ASD. This paper describes the conceptualisation and development of an autism-specific measure of QoL, the Quality of Life in Autism Questionnaire (QoLA) for parents and caregivers of children with ASD, that is suitable to clinical and research settings. Preliminary psychometric properties (reliability and validity) of the measure are also presented. The QoLA has 48 items in two subscales: one comprising QoL items and the second a parent report of how problematic their child’s ASD symptoms are. A study involving 39 families suggested the QoLA has excellent internal consistency as well as good known-groups validity between parents of children with ASD and those who were typically developing. The QoLA also showed good convergent validity with other measures of QoL and ASD symptom severity, respectively. The QoLA may be a valuable assessment tool and merits further psychometric evaluation.
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Agnihotri, Kasturi, Shally Awasthi, Hem Chandra, Uttam Singh, and Savitri Thakur. "Validation of WHO QOL-BREF instrument in Indian adolescents." Indian Journal of Pediatrics 77, no. 4 (March 19, 2010): 381–86. http://dx.doi.org/10.1007/s12098-010-0041-1.
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Alonazi, Wadi B., and Shane A. Thomas. "Quality of Care and Quality of Life: Convergence or Divergence?" Health Services Insights 7 (January 2014): HSI.S13283. http://dx.doi.org/10.4137/hsi.s13283.
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The aim of this study was to explore the impact of quality of care (QoC) on patients’ quality of life (QoL). In a cross-sectional study, two domains of QoC and the World Health Organization Quality of Life-Bref questionnaire were combined to collect data from 1,059 pre-discharge patients in four accredited hospitals (ACCHs) and four non-accredited hospitals (NACCHs) in Saudi Arabia. Health and well-being are often restricted to the characterization of sensory qualities in certain settings such as unrestricted access to healthcare, effective treatment, and social welfare. The patients admitted to tertiary health care facilities are generally able to present themselves with a holistic approach as to how they experience the impact of health policy. The statistical results indicated that patients reported a very limited correlation between QoC and QoL in both settings. The model established a positive, but ultimately weak and insignificant, association between QoC (access and effective treatment) and QoL ( r = 0.349, P = 0.000; r = 0.161, P = 0.000, respectively). Even though the two settings are theoretically different in terms of being able to conceptualize, adopt, and implement QoC, the outcomes from both settings demonstrated insignificant relationships with QoL as the results were quite similar. Though modern medicine has substantially improved QoL around the world, this paper proposes that health accreditation has a very limited impact on improving QoL. This paper raises awareness of this topic with multiple healthcare professionals who are interested in correlating QoC and QoL. Hopefully, it will stimulate further research from other professional groups that have new and different perspectives. Addressing a transitional health care system that is in the process of endorsing accreditation, investigating the experience of tertiary cases, and analyzing deviated data may limit the generalization of this study. Global interest in applying public health policy underlines the impact of such process on patients’ outcomes. As QoC accreditation does not automatically produce improved QoL outcomes, the proposed study encourages further investigation of the value of health accreditation on personal and social well-being.
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Asano, Miho, Paula Rushton, William C. Miller, and Barry A. Deathe. "Predictors of quality of life among individuals who have a lower limb amputation." Prosthetics and Orthotics International 32, no. 2 (January 2008): 231–43. http://dx.doi.org/10.1080/03093640802024955.
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Objective: The purpose of this study was to identify factors that predict an individual's subjective quality of life (QoL) after having a lower limb amputation.Design: Cross-sectional descriptive study design.Subjects: A total of 415 unilateral, above knee (27.0%) and below knee (73.0%) amputees with an average age of 61.9 years (SD = 15.7) who had lost their limb related to vascular (53.0%) or non-vascular (47.0%) etiology.Methods: Medical chart review, questionnaires (Frenchay Activities Index, Interpersonal Support Evaluation List, the Center for Epidemiology Studies – Depression scale, Prosthetic Evaluation Questionnaire mobility subscale, and the Activities-specific Balance Confidence Scale) and a QoL Visual Analogue Scale were assessed using multiple linear regression analysis.Results: The analysis revealed seven significant factors (depression, perceived prosthetic mobility, social support, comorbidity, prosthesis problems, age and social activity participation) as predictors of subjects' perceived QoL. Depression explained 30% of the variation, while the full model explained 42% of the variation.Conclusion: Several modifiable characteristics influence QoL after lower limb amputation including depression and participation in daily living. This finding suggests the importance of addressing individuals' affective status to regain or maintain QoL.
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Trompenaars, Fons J., Erik D. Masthoff, Guus L. Van Heck, Paul P. Hodiamont, and Jolanda De Vries. "The WHO Quality of Life Assessment Instrument (WHOQOL-100)." European Journal of Psychological Assessment 22, no. 3 (January 2006): 207–15. http://dx.doi.org/10.1027/1015-5759.22.3.207.
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This study scrutinizes the ability of the WHO quality of life assessment instrument (WHOQOL-100) to discriminate (1) between psychiatric outpatients and the general population, and (2) between subgroups of psychiatric outpatients. A sample of Dutch adult psychiatric outpatients (N = 410) completed the WHOQOL-100. In addition, DSM-IV Axis-I and Axis-II diagnoses were obtained. Compared with the general population, psychiatric outpatients scored significantly lower on all aspects of self-reported quality of life (QOL). Within the group of outpatients, participants with DSM-IV diagnoses had lower scores than those without. Participants with diagnoses on both Axis-I and Axis-II of DSM-IV (comorbidity) had the lowest self-reported QOL. It is concluded that in psychiatric outpatients, outcome scores of self-reported QOL were negatively related to presence and degree of psychopathology. The WHOQOL-100 has good discriminant ability for psychiatric outpatients.
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Tanaka, Shigeharu, Tetsuya Amano, Yu Inoue, Ryo Tanaka, Hideyuki Ito, and Shinya Morikawa. "Does body mass index influence quality-of-life recovery in individuals who underwent total knee arthroplasty: A prospective study." Journal of Orthopaedics, Trauma and Rehabilitation 27, no. 2 (April 23, 2020): 107–12. http://dx.doi.org/10.1177/2210491720919433.
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Background/Purpose: To clarify the relationship between body mass index (BMI) and quality-of-life (QOL) recovery in individuals who underwent total knee arthroplasty (TKA). Methods: This prospective cohort study included 80 individuals who underwent TKA. The dependent variable was the Japanese Knee Osteoarthritis Measure used for assessing the QOL, and the independent variables were age, sex, BMI, and the Kellgren–Lawrence grade. A hierarchical multiple regression analysis was used to clarify whether BMI was a significant independent variable after accounting for other factors. Results: Sex was found to be the only significant predictor ( β = 0.29, p < 0.05), and BMI was not related to QOL recovery in individuals who underwent TKA. Conclusion: This result suggests that sex was related to QOL recovery and should be assessed and that BMI was not related to QOL recovery in individuals who underwent TKA. These results may help health-care providers to identify individuals who might struggle with QOL recovery.
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McKEE, KEVIN J., STUART G. PARKER, JENNIFER ELVISH, VINCE J. CLUBB, MEGUID EL NAHAS, DEBORAH KENDRAY, and NICOLA CREAMER. "The quality of life of older and younger people who receive renal replacement therapy." Ageing and Society 25, no. 6 (November 2005): 903–23. http://dx.doi.org/10.1017/s0144686x05004046.
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The use of age as a criterion for the allocation of medical resources has been extensively debated internationally. This paper describes a study of the significance of age for the quality of life (QoL) of older and younger people with end-stage renal failure (ESRF) and in receipt of renal replacement therapy (RRT). The study has two components: a structured literature review to characterise the QoL and health-status measurement instruments that have been developed for use with all or specifically older RRT patients; and a longitudinal survey of the QoL domains nominated by older RRT patients by their age and duration of treatment. The literature review found that no validated QoL instrument had been developed specifically for use with older RRT patients. Moreover, there was little correspondence between the QoL domains used in the instruments described in the published literature and those mentioned by the survey participants. Older and younger patients nominated different domains, and their nominations changed with the duration of treatment. No significant differences in QoL scores were found between older and younger patients, but the scores improved significantly between 6–12 and 18–24 months of treatment. The findings suggest that using older age as a criterion for refusing full access to healthcare resources in ESRF is a simplistic and potentially erroneous strategy.
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Hu, Rong, Ying Yang, Bin Wu, Ke Zhu, Miao Miao, Aijun Liao, Wei Yang, and Zhuogang Liu. "Evaluation of Chinese People Quality of Life Who Suffer From Hematologic Diseases." Blood 118, no. 21 (November 18, 2011): 4776. http://dx.doi.org/10.1182/blood.v118.21.4776.4776.
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Abstract Abstract 4776 Objective Now the medical model is transformed from simple biomedicine model to biomedical- psychological-social model and the clinical work also should pay more attention to the patients quality of life(QOL). To study physical function and health-related quality of life in Chinese people with hematologic diseases, we interviewed 64 patients in hematological department of Shengjing hospital. We used medical outcomes study 36-item short-form health survey(SF□ 36) to investigate hematologic patients' QOL and the influencing factors. Method All the data was collected between November 2009 to March 2010, after informed consent was obtained from all participants. We selected 64 patients who were interviewed face to face. They all over 14 years old, 39 males(60.9%) with a mean(SD) age of 43.23(16.71) years. They all suffer from hematologic disease and we listed 14 complications: fatigue, palpitation, insomnia, frequent micturition, anorexia, osteoporosis, night sweat, pain, diarrhea, nausea, constipation, cough, dyspnea and hemoptysis. The SF-36 consists of 36 items which were divided into eight different dimensions of health: physical function(PF), role limitations related to physical problems(RP), role limitations related to emotional problems (RE), social functioning (SF), mental health (MH), vitality (VT), bodily pain(BP) and general health (GH). The health concepts are described by scores ranging from 0 to 100, with higher scores indicating better health. Physical component (PCS) and mental component summary (MCS) scores are calculated from the 8 domains. Physical function was assessed querying limitations in 6 ADL including bathing, dressing, eating, transferring to and from chair, walking, and using the toilet. Each ADL limitation was categorized as any versus no limitation (dichotomous), and total ADL limitations ranging 0–6, categorized into “no”: 0 ADL, “moderate”: 1–2ADL, or “severe limitations”: ≥ 3ADL. As the total ADL can be divide into three degrees: first level is normal fuction: <16; second level is moderate limitations: 16–22; severe limitations of function: >or=22. Result The quality of life is remarkably lower than the normal people in all the aspects in China. The single factor analysis shows age, employment, education, complications and ADL degree have great effect on patients' quality of life. To exclude the interaction of these factors, further multivariable linear regressions indicate the main factors are age, education, complications and ADL degree. That means the above four factors are the independent factors which influence the hematologic patients in China. Conclusion This study found the QOL among hematologic patients was much lower than that among the Chinese general population in every dimension. Therefore, hematologic patients should be given more help to improve their QOL. We also try to find the factors such as gender, age, education, diseases, act influence the QOL. We hope to find a way to improve the QOL of hematologic patients. QOL is people's goal, expectation, standard and the life experiences; it is synthetic indictors to evaluate the burden of diseases. In this study we found age was inversely associated with PF. Educational level had different influence in patients social function and body pain. The patients who had lower educational level is better in SF and BP dimensions. Job status was found to be influence factor for RP. This may be because the patients who at work suffer much more pressure in daily life. Disease is also an important thing which can influence the patients' QOL. Through our investigation we found that activity of daily living is one of the important factors to influence the hematologic patients' QOL. On multivariable linear regressions analysis age, education, complications and ADL all retained an independent association with overall QOL. The hematologic diseases damage their QOL much stronger than others. All above status tell us that hematologic diseases have strong influence to patients' life quality. We should consider about the above four factors and pay more attention to them in order to improve patients' QOL. Disclosures: No relevant conflicts of interest to declare.
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Quirt, I., C. Robeson, C. Y. Lau, M. Kovacs, S. Burdette-Radoux, S. Dolan, S. C. Tang, M. McKenzie, and F. Couture. "Epoetin Alfa Therapy Increases Hemoglobin Levels and Improves Quality of Life in Patients With Cancer-Related Anemia Who Are Not Receiving Chemotherapy and Patients With Anemia Who Are Receiving Chemotherapy." Journal of Clinical Oncology 19, no. 21 (November 1, 2001): 4126–34. http://dx.doi.org/10.1200/jco.2001.19.21.4126.
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PURPOSE: To evaluate efficacy, safety, and quality of life (QOL) changes with epoetin alfa therapy for anemia in patients with nonmyeloid malignancies.PATIENTS AND METHODS: Anemic cancer patients were enrolled onto this prospective, open-label study from 34 centers across Canada. The trial had two cohorts: patients who were and were not receiving chemotherapy during the 16-week study. All patients initially received epoetin alfa 150 IU/kg subcutaneously three times per week. The dose was doubled after 4 weeks for patients who did not experience sufficient response.RESULTS: Of the 183 patients enrolled in the nonchemotherapy cohort, statistically significant and clinically relevant improvements in QOL were observed with epoetin alfa therapy using both the FACT-An questionnaire and linear analog scale assessment. Hemoglobin levels increased significantly (P < .001; mean increase 2.5 g/dL from baseline to end of study) and these increases were positively correlated with improved QOL and change in Eastern Cooperative Oncology Group (ECOG) scores. There was a significant reduction in the percentage of patients who required blood transfusions. The 218 patients in the chemotherapy cohort also experienced significant improvements in QOL, decreased transfusion use, and increased hemoglobin levels that correlated with QOL improvements and change in ECOG scores. Epoetin alfa was well-tolerated in both cohorts.CONCLUSION: Epoetin alfa administered to patients with cancer-related anemia for up to 16 weeks resulted in significantly improved QOL, increased hemoglobin levels, and decreased transfusion use. These benefits were observed in cancer patients who were not receiving chemotherapy as well as those who were.
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Medina-Franco, Heriberto, Miriam N. GarcÍA-Alvarez, Priscila Rojas-GarcÍA, Carolina Trabanino, MÓNica Drucker-Zertuche, and Denise Arcila Psych. "Body Image Perception and Quality of Life in Patients who Underwent Breast Surgery." American Surgeon 76, no. 9 (September 2010): 1000–1005. http://dx.doi.org/10.1177/000313481007600937.
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Quality of Life (QoL) has become a standard measure in assessing the effectiveness of medical interventions. We compared the differences between QoL and body image scale (BIS) in a group of patients who underwent breast surgery, including lumpectomy or conservative surgery, modified radical mastectomy and radical mastectomy with breast reconstruction. We included patients who underwent breast surgery between August of 2005 and June of 2006 in two tertiary referral centers in Mexico City. Two self-administered questionnaires assessing body image perception, BIS and quality of life (SF-36), were assigned and a physician-conducted interview was done. We stratified patients by age, marital status, and scholar grade. The sample comprised 202 patients. The BIS results yielded: the group with a benign lesion demonstrated favorable body image perception when compared with the malignant lesion group. A confirmed diagnosis of malignancy hinders QoL in older and younger age groups. Conservative surgery and breast reconstruction improves QoL in younger patients without significance in the older group. The most significant variable that hinders the BIS and QoL is the cancer diagnosis. Impact of conservative surgery and breast reconstruction in body image perception and quality of life is influenced by patient age and educational level.
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Kim, Suhee, and Junghee Kim. "Analysis of Factors Affecting Quality of Life of Workers in Korea Participating in Leisure Activities Using Quantile Regression." Global Journal of Health Science 9, no. 7 (April 26, 2017): 150. http://dx.doi.org/10.5539/gjhs.v9n7p150.
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INTRODUCTION: This study aimed to identify factors affecting the quality of life (QoL) of workers in Korea participating in leisure activities.METHODS: Cross-sectional survey data were collected from June 10 to June 20, 2013, examining QoL, job stress, social support, serious leisure, and health-related characteristics. Data from 101 participants were analyzed using t-tests, Pearson's correlation, multiple linear regression, and quantile regression.RESULTS: The workers’ mean QoL score was 23.10. Significant predictors of mean QoL score were job stress, social support, and serious leisure. Job stress correlated strongly with QoL in workers who were at 10% (QoL=17.00, p=.013) and 25% (QoL=20.00, p=.001) of the QoL distribution. Social support and serious leisure correlated significantly with QoL in workers who were at 50% (QoL=24.00) and 75% (QoL=27.00) of the QoL distribution.CONCLUSION: Quantile regression analysis identified factors affecting QoL in workers. Therefore, intervention strategies for increasing workers’ QoL should be tailored to workers’ QoL level.
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Datta, Sumona, Robert H. Gilman, Rosario Montoya, Luz Quevedo Cruz, Teresa Valencia, Doug Huff, Matthew J. Saunders, and Carlton A. Evans. "Quality of life, tuberculosis and treatment outcome; a case–control and nested cohort study." European Respiratory Journal 56, no. 2 (May 4, 2020): 1900495. http://dx.doi.org/10.1183/13993003.00495-2019.
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BackgroundGlobal tuberculosis policy increasingly emphasises broad tuberculosis impacts and highlights the lack of evidence concerning tuberculosis-related quality of life (QOL).MethodsParticipants were recruited in 32 Peruvian communities between July 13, 2016 and February 24, 2018 and followed-up until November 8, 2019. Inclusion criteria were age ≥15 years for “patients” (n=1545) starting treatment for tuberculosis disease in health centres; “contacts” (n=3180) who shared a patient's household for ≥6 h·week−1; and randomly selected “controls” (n=277). The EUROHIS-QOL questionnaire quantified satisfaction with QOL, health, energy, activities of daily living (ADL), self, relationships, money and living place.FindingsNewly diagnosed tuberculosis was most strongly associated with lower QOL scores (p<0.001). Patients initially had lower QOL than controls for all EUROHIS-QOL questions (p≤0.01), especially concerning health, ADL and self. Lower initial QOL in patients predicted adverse treatment outcomes and scores <13 points had 4.2-fold (95% CI 2.3–7.6) increased risk of death versus those with higher QOL scores (both p<0.001). Patient QOL was re-assessed 6 months later, and for patients with successful treatment QOL became similar to participants who had never had tuberculosis, whereas patients who did not complete treatment continued to have low QOL (p<0.001). Multidrug-resistant tuberculosis was associated with lower QOL before and during treatment (both p<0.001). Contacts had lower QOL if they lived with a patient who had low QOL score (p<0.0001) or were a caregiver for the patient (p<0.001).ConclusionsTuberculosis was associated with impaired psychosocioeconomic QOL which recovered with successful treatment. Low QOL scores predicted adverse treatment outcome. This brief EUROHIS-QOL eight-item questionnaire quantified the holistic needs of tuberculosis-affected people, potentially guiding patient-centred care.
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YAKUNINA, O. N. "Sociopsychological Status of Epileptic Patients Who Declined to Complete the WHO QOL-100 Technique." International Journal of Mental Health 33, no. 3 (October 2004): 11–17. http://dx.doi.org/10.1080/00207411.2004.11043377.
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Terashima, Kiyoko, Yoko Yoshimura, Kazuyoshi Hirai, and Yukinori Kusaka. "QOL-associated factors in elderly patients who underwent cardiovascular surgery." Environmental Health and Preventive Medicine 17, no. 2 (August 13, 2011): 131–38. http://dx.doi.org/10.1007/s12199-011-0230-1.
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Nilsen, Marci L., Lingyun Lyu, Michael A. Belsky, Leila J. Mady, Dan P. Zandberg, David A. Clump, Heath D. Skinner, Shyamal Das Peddada, Susan George, and Jonas T. Johnson. "Impact of Neck Disability on Health-Related Quality of Life among Head and Neck Cancer Survivors." Otolaryngology–Head and Neck Surgery 162, no. 1 (October 15, 2019): 64–72. http://dx.doi.org/10.1177/0194599819883295.
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Objective Although neck impairment has been described following surgical resection, limited studies have investigated its prevalence in nonsurgical treatment. The purpose of this study is to determine the prevalence and predictors of neck disability following head and neck cancer (HNC) treatment and to explore its association with quality of life (QOL). Study Design Cross-sectional study. Setting HNC survivorship clinic. Subjects and Methods We identified 214 survivors who completed treatment ≥1 year prior to evaluation in the clinic. Self-reported neck impairment was measured using the Neck Disability Index. QOL was measured using the University of Washington QOL Questionnaire, with physical and social subscale scores calculated. Regression analysis and trend tests were employed to explore associations. Results Over half of survivors (54.2%) reported neck disability. The odds of neck disability in survivors who received nonsurgical treatment and those who received surgery plus adjuvant treatment were 3.46 and 4.98 times higher compared to surgery alone ( P = .008, P = .004). Survivors who underwent surgery only had higher physical and social QOL than those who received nonsurgical treatment (physical QOL: P < .001, social QOL: P = .023) and those who received surgery plus adjuvant treatment (physical QOL: P < .001, social QOL: P = .039). Conclusion This study revealed a high prevalence of neck disability following nonsurgical treatment. While neck disability is an established sequela of surgical resection, the impact of nonsurgical treatment has gone unrecognized. Early identification and intervention to prevent progression of neck disability are crucial to optimize QOL.
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Yamashiro, Shigeo, Toru Nishi, Kazunari Koga, Tomoaki Goto, Daisuke Muta, Jun-ichi Kuratsu, and Shodo Fujioka. "Postoperative quality of life of patients treated for asymptomatic unruptured intracranial aneurysms." Journal of Neurosurgery 107, no. 6 (December 2007): 1086–91. http://dx.doi.org/10.3171/jns-07/12/1086.
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Object The aim of this study was to assess the quality of life (QOL) of patients who underwent surgery for asymptomatic unruptured intracranial aneurysms (UIAs). Methods The authors assessed QOL in 149 patients who had undergone microsurgical clipping of asymptomatic UIAs. They surveyed these patients using universal methods such as the 36-Item Short Form Health Survey (SF-36) for health-related QOL and the Hospital Anxiety and Depression Scale for anxiety and depression assessments. Results The patients' mean scores for each of the eight domains of SF-36 were comparable to those of a Japanese reference population. Analysis of data from the average-QOL and low-QOL subgroups showed that the low-QOL group contained a higher number of patients with preexisting heart diseases and restricted activities of daily living. Operative procedures and complications did not affect QOL. Conclusions Because 86% of the patients who underwent surgery manifested a QOL similar to the reference population, the authors suggest that elective surgery for asymptomatic UIAs is a reasonable treatment, especially in patients who are troubled by the risk of rupture. Postoperative decreases in QOL are not invariably attributable to the operation or its associated complications, but may be correlated with other chronic disorders. To select the appropriate treatment for asymptomatic UIAs, neurosurgeons and patients need information on the expected postoperative QOL.
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Ventegodt, Søren, Trine Flensborg-Madsen, Niels Jørgen Andersen, Mohammed Morad, and Joav Merrick. "Clinical Holistic Medicine: A Pilot Study on HIV and Quality of Life and a Suggested Cure for HIV and AIDS." Scientific World JOURNAL 4 (2004): 264–72. http://dx.doi.org/10.1100/tsw.2004.24.
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This study was undertaken to examine the association between the immunological impact of HIV (measured by CD4 count) and global self-assessed quality of life (QOL) (measured with QOL1) for people suffering from HIV, to see if the connection was large and statistically strong enough to support our hypothesis of a strong QOL-immunological connection through the nonspecific, nonreceptor-mediated immune system, and thus to give a rationale for a holistic cure for HIV. This cross-sectional population study in Uganda included 20 HIV infected persons with no symptoms of AIDS and a CD4 count above 200 mill./liter. The main outcome measures were CD4 count, global QOL measured with the validated questionnaire QOL1, translated to Luganda and translated back to English. We found a large, clinically significant correlation between the number of T-helper cells (CD4) and global self-assessed quality of life (QOL1) (r = 0.57, p = 0.021), when controlled for age, gender, and years of infection. Together with other studies and holistic medicine theory, the results have given rationale for a holistic cure for HIV. We suggest, based on our findings and theoretical considerations, that HIV patients who improve their global QOL, also will improve their CD4 counts. Using the technique of holistic medicine based on the life mission theory and the holistic process theory of healing, we hypothesize that the improvement of QOL can have sufficient biological effect on the CD4, which could avoid or postpone the development of AIDS. A holistic HIV/AIDS cure improving the QOL draws on hidden resources in the person and is thus affordable for everybody. Improving global QOL also means a higher consciousness and a more ethical attitude, making it more difficult for the HIV-infected person to pass on the infection.
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Lathan, Christopher S., Ruth N. Akindele, Ludmila Svoboda, and Daniel A. Gundersen. "Self-reported financial stress among patients evaluated at a community cancer program." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 6553. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.6553.
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6553 Background: Cancer related financial stress has been linked to a multitude of factors including socio-economic status, but its impact on the quality of life (QOL) for underserved populations is less well characterized. We evaluated patient reported financial stress, QOL, and quality of health (QOH) at an outreach cancer program located in a federally qualified health center. Methods: Study participants were interviewed at initial clinic visit for financial stress, QOH and QOL between January 2012 and December 2016. Demographic information, insurance coverage, clinical parameters, and comorbidities were abstracted from participants’ medical records. Responses to the financial stress index question “how difficult is it for you or your family to meet monthly payment of your/your family bills?” and overall QOL and QOH of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 were analyzed. Proportional odds logistic regression models were constructed for 5-point quality of life measures and three levels of financial toxicity. Results: Of the 288 participants analyzed, 52% and 12% reported somewhat and extreme financial stress. In an adjusted analysis, patients who reported financial stress were more likely to be younger in age (OR = 4.03, p < 0.001) unemployed (OR = 3.24, p = 0.002), have less than bachelor’s degree (OR = 0.035, p = 0.018), insured by Medicaid (OR = 3.22, p < 0.011), and were more likely to rate their QOL (OR = 3.76, p = 0.031) as poor, compared to those without financial stress. Race, gender, presence of cancer diagnosis and comorbidities were not associated with financial distress. Independent predictors of poor QOL were disability (OR = 3.12, p = 0.005), depression (OR = 2.12, p = 0.007) and extreme financial difficulty (OR = 2.57, p = 0.011). There was a nearly perfect positive correlation between overall QOL and QOH (r = 0.984, p < 0.001). Conclusions: There is a high prevalence of financial burden among underserved minority patients seeking cancer related care, and this is closely associated with poor quality of life. Interventions targeting cancer disparities need to assess financial stress in order to address this issue.
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Jiang, Tingting, Xin Zhou, Hui Wang, Mingyu Luo, Xiaohong Pan, Qiaoqin Ma, and Lin Chen. "Psychosocial Factors Associated with Quality of Life in Young Men Who Have Sex with Men Living with HIV/AIDS in Zhejiang, China." International Journal of Environmental Research and Public Health 16, no. 15 (July 25, 2019): 2667. http://dx.doi.org/10.3390/ijerph16152667.
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Objectives: To explore the quality of life (QOL) status and related factors in young human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) aged 16 to 24 years in Zhejiang province. Methods: A cross-sectional study was conducted in 22 counties of Zhejiang province, and 395 subjects took part in our research. A t-test, one-way Analysis of variance (ANOVA), and multivariate stepwise linear regression analysis were used to investigate the factors associated with QOL in young HIV-infected MSM. Results: The total score on the QOL was 86.86 ± 14.01. The multivariate stepwise linear regression analysis revealed that self-efficacy and discrimination were associated with all domains on the QOL assessment, monthly income was associated with QOL for all domains except spirituality and consistent condom use during oral sex with men in the past three months was associated with QOL for all domains except the relationship domain. Those individuals within the group of young HIV-infected MSM who have higher self-efficacy, a higher monthly income, greater social support, safer sexual behaviors, a higher level of education, and a higher cluster of differentiation 4 (CD4) count have a better QOL. Conclusions: These findings suggest that to improve the QOL of this population, greater emphasis should be placed on improving social support, self-efficacy, and antiviral therapy adherence and on reducing discrimination, disease progression, and high-risk behaviors.
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Bodner, E., S. Cohen-Fridel, and A. Yaretzky. "Perceived quality of life and ageism among elderly people living in sheltered housing and in the community." European Psychiatry 26, S2 (March 2011): 1172. http://dx.doi.org/10.1016/s0924-9338(11)72877-2.
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IntroductionAlthough there are studies on ageist attitudes and perceptions of quality of life (QoL) among elderly people, no publications exist that compare ageist attitudes and QoL perceptions among elderly people who live in private sector sheltered housing (PRSSH) and in the community.ObjectivesTo map the differences and understand the relations between QoL and negative social perceptions of one’s own age group among older adults, living in PRSSH and in the community.Aims(1) To examine if there are differences in ageist attitudes and perceptions of quality of life (QoL), and(2) to understand the role of QoL in explaining ageist attitudes among these two groups of elderly people.MethodsThe sample included 126 participants, aged 64–94, who live in PRSSH or in the community. The participants completed Fraboni et al. scale of ageism, a QoL inventory (SF-36 inventory), which provides scores on measures such as physical functioning, mental health and social functioning, and answered demographic questions.ResultsMultivariate analyses of covariance (MANCOVA) partially supported our hypotheses that elderly people who live in PRSSH will demonstrate more ageist attitudes towards people of their own age, and report a lower QoL than elderly people who live in the community.Gender also had a distinctive effect on ageism and QoL among individuals in PRSSH. These findings were supported by regression analyses.ConclusionsAlthough PRSSH may offer luxurious living conditions, the current study shows that living in an age segregated environment, may trigger negative self-perceptions of old age and decrease QoL.
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Takahashi, Shun, Tsunahiko Hirano, Kasumi Yasuda, Tomohiro Donishi, Kazuyoshi Suga, Keiko Doi, Keiji Oishi, et al. "Impact of Frailty on Hippocampal Volume in Patients with Chronic Obstructive Pulmonary Disease." Biomedicines 9, no. 9 (August 28, 2021): 1103. http://dx.doi.org/10.3390/biomedicines9091103.
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Brain frailty may be related to the pathophysiology of poor clinical outcomes in chronic obstructive pulmonary disease (COPD). This study examines the relationship between hippocampal subfield volumes and frailty and depressive symptoms, and their combined association with quality of life (QOL) in patients with COPD. The study involved 40 patients with COPD. Frailty, depressive symptoms and QOL were assessed using Kihon Checklist (KCL), Hospital Anxiety and Depression Scale (HADS), and World Health Organization Quality of Life Assessment (WHO/QOL-26). Anatomical MRI data were acquired, and volumes of the hippocampal subfields were obtained using FreeSurfer (version 6.0). Statistically, HADS score had significant association with WHO/QOL-26 and KCL scores. KCL scores were significantly associated with volumes of left and right whole hippocampi, presubiculum and subiculum, but HADS score had no significant association with whole hippocampi or hippocampal subfield volumes. Meanwhile, WHO/QOL-26 score was significantly associated with volume of the left CA1. There was a significant association between frailty, depression, and QOL. Hippocampal pathology was related to frailty and, to some extent, with QOL in patients with COPD. Our results suggest the impact of frailty on hippocampal volume and their combined associations with poor QOL in COPD.
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Miller, Deborah M., Francois Bethoux, David Victorson, Cindy J. Nowinski, Sarah Buono, Jin-Shei Lai, Katy Wortman, James L. Burns, Claudia Moy, and David Cella. "Validating Neuro-QoL short forms and targeted scales with people who have multiple sclerosis." Multiple Sclerosis Journal 22, no. 6 (August 3, 2015): 830–41. http://dx.doi.org/10.1177/1352458515599450.
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Background: Multiple sclerosis (MS) is a chronic, progressive, and disabling disease of the central nervous system with dramatic variations in the combination and severity of symptoms it can produce. The lack of reliable disease-specific health-related quality of life (HRQL) measures for use in clinical trials prompted the development of the Neurology Quality of Life (Neuro-QOL) instrument, which includes 13 scales that assess physical, emotional, cognitive, and social domains, for use in a variety of neurological illnesses. Objective: The objective of this research paper is to conduct an initial assessment of the reliability and validation of the Neuro-QOL short forms (SFs) in MS. Methods: We assessed reliability, concurrent validity, known groups validity, and responsiveness between cross-sectional and longitudinal data in 161 recruited MS patients. Results: Internal consistency was high for all measures (α = 0.81–0.95) and ICCs were within the acceptable range (0.76–0.91); concurrent and known groups validity were highest with the Global HRQL question. Longitudinal assessment was limited by the lack of disease progression in the group. Conclusions: The Neuro-QOL SFs demonstrate good internal consistency, test-re-test reliability, and concurrent and known groups validity in this MS population, supporting the validity of Neuro-QOL in adults with MS.
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Doran, Patty, Sorrel Burden, and Nick Shryane. "Older People Living Well Beyond Cancer: The Relationship Between Emotional Support and Quality of Life." Journal of Aging and Health 31, no. 10 (September 10, 2018): 1850–71. http://dx.doi.org/10.1177/0898264318799252.
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Objective: To investigate the influence of emotional support on the quality of life (QoL) of older cancer survivors. Method: We use data from the English Longitudinal Study of Ageing to assess the relationship between perceived emotional support and QoL, comparing people who were cancer survivors ( n = 533) to people without cancer ( n = 8,203). Results: Most people reported high emotional support and had good QoL ( M = 42.57, scale = 0-57). However, linear regression modeling showed cancer survivors had on average slightly lower QoL (–2.10 SE = 0.82). Those who reported having low support reported much poorer QoL; this relationship was similar for both cancer survivors and people without cancer. Discussion: The impact of low emotional support on QoL compounds with the independent detrimental effect of being a cancer survivor. Interventions that increase emotional support are likely to improve QoL for cancer survivors.
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Desai, Kanan T., Prakash B. Patel, Anupam Verma, and RK Bansal. "Environment and psychosocial factors are more important than clinical factors in determining quality of life of HIV-positive patients on antiretroviral therapy." Tropical Doctor 50, no. 3 (March 5, 2020): 180–86. http://dx.doi.org/10.1177/0049475520908180.
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Assessing quality of life (QOL) outcome helps to show the effect of antiretroviral therapy (ART) on the subjective perception of its benefits among patients with HIV. A cross-sectional assessment of QOL, using the World Health Organization WHOQOL-HIV, on 204 HIV patients taking ART in western India showed patients with HIV on ART as having the best QOL score in the spiritual domain and the worst in the environment domain. Patients who are single, highly educated, of higher occupational status, with no HIV-positive children, not undergoing frequent hospital admissions, with access to a counsellor for support, who are not stigmatised or discriminated against due to HIV status, who do not have guilt or suicidal ideas, and who are theist, tend to have a better QOL, irrespective of their clinical condition or ART regimen. Patients’ personal perceptions and feelings, societal support or stigma, and sociodemographic status have a more significant influence on QOL than clinical variables.
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Major, Piotr, Tomasz Stefura, Błażej Dziurowicz, Joanna Radwan, Michał Wysocki, Piotr Małczak, and Michał Pędziwiatr. "Quality of Life 10 Years After Bariatric Surgery." Obesity Surgery 30, no. 10 (June 13, 2020): 3675–84. http://dx.doi.org/10.1007/s11695-020-04726-7.
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Abstract Purpose Improvement of the quality of life after bariatric surgery is an important outcome of the treatment. Assessing the long-term QoL results provides better insights into the effectiveness of bariatric surgery. Materials and Methods This is a cohort study including patients who underwent bariatric surgery between June 2009 and May 2010 in one academic center. Patients underwent either laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB). Overall, 34 patients underwent LSG (52.3%) and 31 patients underwent LRYGB (47.7%). Preoperatively, and after 1 and 10 years, QoL was assessed using two standardized questionnaires: SF-36 and MA-QoLII. After 10 years, 72% of patients filled out these questionnaires. Results The global QoL score before surgery was 48.3 ± 20.6. At the 1-year follow-up, the global total QoL score was 79.7 ± 9.8. At the 10-year follow-up, the global total QoL score was 65.1 ± 21.4. There was a significant increase in total QoL between measurements before the operation and 10 years after surgery in the whole study group (p = 0.001) and for patients who underwent LSG (p = 0.001). There was no significant difference between total QoL prior to surgery and 10 years after for patients who underwent LRYGB (p = 0.450). Conclusion LSG led to significant improvement in QoL.
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Lin, Lilie L., Justin C. Brown, Saya Segal, and Kathryn H. Schmitz. "Quality of Life, Body Mass Index, and Physical Activity Among Uterine Cancer Patients." International Journal of Gynecologic Cancer 24, no. 6 (July 2014): 1027–32. http://dx.doi.org/10.1097/igc.0000000000000166.
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ObjectiveThe purpose of this study was to assess the independent and joint effects of body mass index (BMI) and physical activity (PA) on overall quality of life (QoL) in survivors of uterine cancer.MethodsWe conducted a survey among uterine cancer patients who received curative therapy at the University of Pennsylvania between 2006 and 2010. Surveys assessed the weight, height, PA (college alumnus survey), and QoL (Functional Assessment of Cancer Therapy–Gynecologic Oncology Group).ResultsThe response rate to the survey was 43%. Among 213 patients, the mean (SD) BMI was 31.1 (8.9) kg/m2, and 48% reported greater than or equal to 150 min·wk−1of PA. Higher BMI was independently associated with poorer overall QoL (P= 0.050), including physical (P= 0.002) and functional well-being (P= 0.008). Higher min·wk−1of PA was not independently associated with any QoL outcome. However, among patients who engaged in greater than or equal to 150 min·wk−1of PA, the negative association between BMI and overall QoL was attenuated (P= 0.558), whereas among patients who engaged in less than 150 min·wk−1of PA, the negative association between BMI and overall QoL persisted (P= 0.025). Among patients who engaged in greater than or equal to 150 min·wk−1of PA, the negative association between BMI and physical and functional well-being was attenuated (P= 0.765 andP= 0.284), whereas among patients who engaged in less than 150 min·wk−1of PA, the negative association between BMI and physical and functional well-being persisted (P< 0.001 andP= 0.010), respectively.ConclusionsBody mass index is associated with poorer QoL among uterine cancer patients. The findings from this cross-sectional study are consistent with the hypothesis that endometrial cancer survivors who are able to perform 150 min/wk of PA may be protected from the negative effects of BMI on QoL.
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Hargreaves, Shila Minari, Eduardo Yoshio Nakano, Heesup Han, António Raposo, Antonio Ariza-Montes, Alejandro Vega-Muñoz, and Renata Puppin Zandonadi. "Quality of Life of Vegetarians during the COVID-19 Pandemic in Brazil." Nutrients 13, no. 8 (July 30, 2021): 2651. http://dx.doi.org/10.3390/nu13082651.
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Health emergencies such as the COVID-19 pandemic can negatively impact quality of life (QoL) due to higher levels of stress, social isolation, and uncertainties. In this scenario, distinct population groups might react differently. Vegetarians, who follow a non-conventional dietary pattern, could be more vulnerable to the abrupt changes in normal life routine and economic instability. Therefore, this study aimed at evaluating if the current pandemic situation somehow affected vegetarians’ QoL. A cross-sectional study was carried out in Brazil between 28 July and 14 September 2020 to evaluate the QoL in vegetarians during the pandemic period. Vegetarian adults replied to an online survey that included the VEGQOL and WHOQOL-BREF instruments to evaluate QoL and questions related to the COVID-19 pandemic. A total of 1282 individuals participated. Only 3.8% had tested positive for COVID-19, but 39.9% affirmed having a family member who tested positive for the disease. Almost half (46.3%) of the sample had an income drop due to the pandemic. Results of QoL scores in the different subcategories of vegetarians were similar to previously published data. Individuals who had already tested positive for COVID-19 had lower QoL scores than those who did not test positive, but only in the VEGQOL. QoL was lower for the participants who declared that Sars-Cov-2 had already infected a family member for almost all the parameters evaluated. On the other hand, an income drop affected QoL only partially. Studying how vegetarians are influenced by such conditions contributes to the generation of relevant data that can be used to support healthcare and public policies in the future.
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Ratcliff, Chelsea G., Sarah Prinsloo, Michael Richardson, Laura Baynham-Fletcher, Richard Lee, Alejandro Chaoul, Marlene Z. Cohen, Marcos de Lima, and Lorenzo Cohen. "Music Therapy for Patients Who Have Undergone Hematopoietic Stem Cell Transplant." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/742941.
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Objectives. This study examines the short- and long-term QOL benefits of a music therapy intervention for patients recovering from hematopoietic stem cell transplantation (HSCT).Methods. Ninety allogeneic HSCT patients, after transplant, were randomized to receive ISO-principle (i.e., mood matching) based music therapy (MT;n=29), unstructured music (UM;n=30), or usual care (UC;n=31) for four weeks. The ISO principle posits that patients may shift their mood from one state to another by listening to music that is “equal to” the individual’s initial mood state and subsequently listening to music selections that gradually shift in tempo and mood to match the patient’s desired disposition. Participants in MT and UM groups developed two audio CDs to help them feel more relaxed and energized and were instructed to use the CDs to improve their mood as needed. Short-term effects on mood and long-term effects on QOL were examined.Results. MT and UM participants reported improved mood immediately after listening to CDs; the within-group effect was greater for UM participants compared to MT participants. Participant group was not associated with long-term QOL outcomes.Conclusions. Music listening improves mood acutely but was not associated with long-term benefits in this study.
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Morton, Emma, Venkat Bhat, Peter Giacobbe, Wendy Lou, Erin E. Michalak, Trisha Chakrabarty, Benicio N. Frey, et al. "Impacts on Quality of Life with Escitalopram Monotherapy and Aripiprazole Augmentation in Patients with Major Depressive Disorder: A CAN-BIND Report." Pharmacopsychiatry 54, no. 05 (March 2, 2021): 225–31. http://dx.doi.org/10.1055/a-1385-0263.
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ABSTRACT Introduction Many individuals with major depressive disorder (MDD) do not respond to initial antidepressant monotherapy. Adjunctive aripiprazole is recommended for treatment non-response; however, the impacts on quality of life (QoL) for individuals who receive this second-line treatment strategy have not been described. Methods We evaluated secondary QoL outcomes in patients with MDD (n=179). After 8 weeks of escitalopram, non-responders (<50% decrease in clinician-rated depression) were treated with adjunctive aripiprazole for 8 weeks (n=97); responders continued escitalopram (n=82). A repeated-measures ANOVA evaluated change in Quality of Life Enjoyment and Satisfaction Short Form scores. QoL was described relative to normative benchmarks. Results Escitalopram responders experienced the most QoL improvements in the first treatment phase. For non-responders, QoL improved with a large effect during adjunctive aripiprazole treatment. At the endpoint, 47% of patients achieving symptomatic remission still had impaired QoL. Discussion Individuals who were treated with adjunctive aripiprazole after non-response to escitalopram experienced improved QoL, but a substantial degree of QoL impairment persisted. Since QoL deficits may predict MDD recurrence, attention to ways to support this outcome is required.
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Detsyk, Oryna Z., Oleksandra P. Bratsyun, and Раvlo M. Babich. "QUALITY OF LIFE OF PATIENTS RECEIVING HOME-BASED PALLIATIVE CARE FROM FAMILY PHYSICIANS AND MOBILE PALLIATIVE CARE TEAM." Wiadomości Lekarskie 73, no. 8 (2020): 1681–89. http://dx.doi.org/10.36740/wlek202008118.
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The aim: To evaluate the quality of life (QoL) of palliative patients receiving general palliative care and the impact of palliative care provided by mobile palliative care team (MPCT) on their QoL. Materials and methods: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core30 (QLQ-C30) was used to evaluate QoL of 219 palliative patients receiving general palliative care from family physicians in the Center for primary health care of Uzhhorod city, Ukraine. In the second part of the study, the subgroup of 25 patients who had at least one of fifteen QLQ-C30 scales evaluated lower than 50 points were selected. They were provided with PC from the MPCT for 2 weeks and their QoL was measured again. Results: For the patients who received general palliative care from a family physicians mean m (SD) QoL value was 38.63 (16.9), and the main symptoms that affected QoL were fatigue 48.60 (23.30) and pain 46.11 (20.97). The most impact on QoL scores had role (rs=0,430;), emotional (0.321) and physical (0.301) functioning and such symptoms as pain (-0.392), insomnia (-0.311), dyspnoea (-0.294), financial difficulties (-0.255). For the patients who received palliative care from MPCT mean the mean QoL score increased by 30.0 points, mean pain score decreased by 42.22 points, fatigue score decreased by 38.0 points and level of financial difficulties also decreased by 76.0 points. Conclusions: The involvement of the MPCT could have a significant positive impact on the QoL of palliative patients.
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Wang, Qi Feng, Sarah Rouse, Margaret Hay, and Samuel Menahem. "Does Previous Cardiac Surgery Predict Impaired Quality of Life in Adults With Congenital Heart Disease?" World Journal for Pediatric and Congenital Heart Surgery 11, no. 3 (April 15, 2020): 304–9. http://dx.doi.org/10.1177/2150135120908185.
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Background: Improved survival of children with congenital heart disease (CHD) into adult life has led to further study of their quality of life (QoL) and its determinants. The QoL including the symptoms of anxiety and depression of adults with CHD was analyzed to determine the relationship, if any, between prior cardiac surgery and QoL. Methods: Adults with CHD who were recruited from a single community-based cardiology practice completed self-reported questionnaires on their QoL, which included symptoms of anxiety and depression. Standard linear regression analysis was used to determine whether prior cardiac surgery predicted lower QoL scores. Results: One hundred forty-nine adult patients with CHD were sent QoL questionnaires. Completed questionnaires were received from 135 patients: 71 (53%) males and 64 (47%) females, with a mean age of 26.3 years (standard deviation: 7.8, min: 17, max: 49). Respondents were assigned to two groups: those who had (n = 89, 66%) or had not (n = 46, 34%) previously undergone one or more cardiac surgical interventions. Results from standard linear regression analyses revealed no predictive relationship between history of previous cardiac surgery, whether one or more operations, and QoL. Conclusions: Among adult patients with CHD who completed QoL questionnaires, we observed no association between a patient’s history of prior cardiac surgery and self-reported QoL measures. This welcome and important finding may be a reflection of the good functional capacity of both groups (postsurgical and nonsurgical) irrespective of the original CHD diagnosis and need for surgical intervention.
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Tan, Siok Swan, Irene N. Fierloos, Xuxi Zhang, Elin Koppelaar, Tamara Alhambra-Borras, Tasos Rentoumis, Greg Williams, et al. "The Association between Loneliness and Health Related Quality of Life (HR-QoL) among Community-Dwelling Older Citizens." International Journal of Environmental Research and Public Health 17, no. 2 (January 17, 2020): 600. http://dx.doi.org/10.3390/ijerph17020600.
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Background: This study aimed to assess the association between loneliness and Health-Related Quality of Life (HR-QoL) among community-dwelling older citizens in five European countries. We characterize loneliness broadly from an emotional and social perspective. Methods: This cross-sectional study measured loneliness with the 6-item De Jong Gierveld Loneliness Scale and HR-QoL with the 12-Item Short-Form Health Survey. The association between loneliness and HR-QoL was examined using multivariable linear regression models. Results: Data of 2169 citizens of at least 70 years of age and living independently (mean age = 79.6 ± 5.6; 61% females) were analyzed. Among the participants, 1007 (46%) were lonely; 627 (29%) were emotionally and 575 (27%) socially lonely. Participants who were lonely experienced a lower HR-QoL than participants who were not lonely (p ≤ 0.001). Emotional loneliness [std-β: −1.39; 95%-CI: −1.88 to −0.91] and social loneliness [−0.95; −1.44 to −0.45] were both associated with a lower physical HR-QoL. Emotional loneliness [−3.73; −4.16 to −3.31] and social loneliness [−1.84; −2.27 to −1.41] were also both associated with a lower mental HR-QoL. Conclusions: We found a negative association between loneliness and HR-QoL, especially between emotional loneliness and mental HR-QoL. This finding indicates that older citizens who miss an intimate or intense emotional relationship and interventions targeting mental HR-QoL deserve more attention in policy and practice than in the past.
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Yu, Hyeong Won, Ah Reum An, Hye In Kang, Yong Joon Suh, Hyungju Kwon, Su-jin Kim, Young Jun Chai, et al. "Does Thyroidectomy Impact Quality of Life: Retrospective Case–Control Study of Post-Thyroidectomy Patients and Matched Individuals from the General Population." Medicina 56, no. 11 (November 10, 2020): 603. http://dx.doi.org/10.3390/medicina56110603.
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Background and objectives: The study assesses quality of life (QoL) in patients who underwent thyroidectomy compared to the general population. Materials and Methods: QoL data from post-thyroidectomy patients and individuals with no subjective health concerns, who had attended a routine health screening visit, were evaluated. QoL was assessed using the modified version of Korean Short Form 12 questionnaire (SF-12). Patients and controls were matched using the propensity score approach and a ratio of 1:4. Results: Data from a total of 105 patients and 420 controls were analyzed. For five SF-12 items, lower QoL was found in patients (p < 0.05). Multivariate analysis revealed that a follow-up duration of <1-year, female sex, and an age of >50 years were independent risk factors. No significant difference was found between controls and patients who were >1-year post-surgery. Conclusions: For specific SF-12 items, QoL was lower in post-thyroidectomy patients than in controls. No intergroup difference in QoL was found >1-year post-surgery.
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Brähler, Elmar, Holger Mühlan, Cornelia Albani, and Silke Schmidt. "Teststatistische Prüfung und Normierung der deutschen Versionen des EUROHIS-QOL Lebensqualität-Index und des WHO-5 Wohlbefindens-Index." Diagnostica 53, no. 2 (April 2007): 83–96. http://dx.doi.org/10.1026/0012-1924.53.2.83.
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Zusammenfassung. Der Beitrag berichtet über die teststatistische Prüfung und Normierung der deutschen Versionen des EUROHIS-QOL 8 Item Index (EUROHIS-QOL) zur Erfassung der generischen Lebensqualität und des Wohlbefindens-Index der WHO (WHO-5) zur Erfassung der Wohlbefindens aus Sicht der Befragten. Datengrundlage bildet eine repräsentative Stichprobe der bundesdeutschen Bevölkerung aus dem Jahr 2004. Die teststatistische Prüfung verweist auf gute psychometrische Eigenschaften des EUROHIS-QOL Index. Obgleich Modifikationsmöglichkeiten bestehen, wird die Selektion von Items ausgeschlossen, weil dies den komzeptuellen Vorgaben der Indexkonstruktion widersprechen würde. Die Ergebnisse der teststatistischen Prüfung des WHO-5 sind hinsichtlich der psychometrischen Eigenschaften als ausgezeichnet einzuschätzen. Erstmals werden geschlechts- und altersgruppenspezifische Normwerte für die deutschsprachigen Versionen der beiden Instrumente vorgelegt.
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Tay, Laura, Kia Chong Chua, Mark Chan, Wee Shiong Lim, Yue Ying Ang, Evonne Koh, and Mei Sian Chong. "Differential perceptions of quality of life (QoL) in community-dwelling persons with mild-to-moderate dementia." International Psychogeriatrics 26, no. 8 (April 23, 2014): 1273–82. http://dx.doi.org/10.1017/s1041610214000660.
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ABSTRACTBackground:Discordance between patient- and caregiver-reported quality of life (QoL) is well recognized. This study sought to (i) identify predictors of discrepancy between patient- and caregiver-rated QoL amongst community-dwelling persons with mild-to-moderate dementia, and (ii) differentiate between patients who systematically rate their QoL lower versus those who rate their QoL higher relative to their caregiver ratings.Methods:We recruited 165 patient–caregiver dyads with mild-to-moderate dementia. Quality of life in Alzheimer's disease (QoL-AD) scale was administered separately to patients and caregivers. Data on socio-demographics, interpersonal relationship, and disease-related characteristics (cognitive performance, mood, neuropsychiatric symptoms, functional ability, and caregiver burden) were collected. Patient–caregiver dyads were categorized based on whether patient-rated QoL was lower or higher than their respective caregiver ratings. Univariate analyses and multiple regression models were performed to identify predictors of dyadic rating discrepancy.Results:Mean patient-rated QoL was significantly higher than caregiver rating (mean difference: 3.8 ± 7.1, p < 0.001). Majority (111 (67.2%)) of patients had more positive self-perceived QoL (QoL-ADp (QoL-AD self rated by the patient) > QoL-ADc (QoL-AD proxy-rated by a caregiver)), compared with those (44 (26.7%)) with poorer self-perceived QoL (QoL-ADp < QoL-ADc). Patient's education level, depressive symptoms, and severity of neuropsychiatric symptoms predicted magnitude of discrepancy. Depression (OR = 1.17, 95% CI = 1.02–1.35) and being cared for by other relative (non-spouse/adult child; OR = 7.54, 95% CI = 1.07–53.03) predicted poorer self-perceived QoL.Conclusions:Dyadic rating discrepancy in QoL should draw the clinician's attention to patient depression and neuropsychiatric symptoms. Consideration should also be given to nature of patient–caregiver relationship when discordance between patient and caregiver assessments of QoL is observed.
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Hay-McCutcheon, Marcia, and Xin Yang. "Geographical Residency and Quality of Life in Adults with and without Hearing Loss." Innovation in Aging 4, Supplement_1 (December 1, 2020): 854. http://dx.doi.org/10.1093/geroni/igaa057.3143.
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Abstract There is an increased interest in the impact that hearing loss has on general well-being, including overall quality of life (QOL). The Quality of Life Inventory (QOLI), the Charlson Comorbidity Index and an Accessibility to Health Care questionnaire were administered to 108 participants. For adults with hearing loss who did not have access to hearing health care, lower QOL scores were reported compared to those with access to hearing health care, but this finding was not significant. Effect size calculations indicated that adults with hearing loss who lived in the most rural regions of Alabama, had lower reported QOL scores than their counterparts who had hearing within normal limits. Finally, those with higher incomes, who were older, and who had fewer physical disorders reported higher QOL compared to those with lower incomes, were younger, and who had more physical ailments. Part of a symposium sponsored by the Mental Health Practice and Aging Interest Group.
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Slovacek, Ladislav, Birgita Slovackova, Ladislav Jebavy, and Zuzana Macingova. "Psychosocial, health and demographic characteristics of quality of life among patients with acute myeloid leukemia and malignant lymphoma who underwent autologous hematopoietic stem cell transplantation." Sao Paulo Medical Journal 125, no. 6 (November 2007): 359–61. http://dx.doi.org/10.1590/s1516-31802007000600012.
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CONTEXT AND OBJECTIVE: This study evaluated the effect of selected psychosocial, health and demographic characteristics of quality of life (QOL) among patients treated with autologous hematopoietic stem cell transplantation (HSCT). DESIGN AND SETTING: This was a retrospective study at Charles University Hospital, Hradec Kralove. METHODS: The Czech version of the international generic European Quality-of-Life questionnaire (EQ-5D) was applied to evaluate QOL among patients with acute myeloid leukemia (AML) and malignant Hodgkin’s and non-Hodgkin’s lymphoma (ML). The total number of respondents was 36: 12 with AML (seven males and five females) and 24 with ML (11 males and 13 females). The mean age of AML respondents was 46 years and the mean age of ML respondents was 44.5 years. RESULTS: Age, smoking status and education level had statistically significant effects on QOL among AML respondents (p < 0.05), and age had a statistically significant effect on QOL among ML respondents (p < 0.05). The overall QOL among AML and ML respondents was generally good: the mean EQ-5D score among AML respondents was 71.5% and among ML respondents it was 82.7%. CONCLUSION: The QOL among AML and ML respondents treated with autologous HSCT was good. However, patients more than 50 years old, smokers and patients with lower education levels presented worse QOL. These findings need to be better evaluated in longitudinal studies, using large samples.
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Bodner, Ehud, Sara Cohen-Fridel, and Abraham Yaretzky. "Sheltered housing or community dwelling: quality of life and ageism among elderly people." International Psychogeriatrics 23, no. 8 (June 21, 2011): 1197–204. http://dx.doi.org/10.1017/s1041610211001025.
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ABSTRACTBackground: Previous studies have found correlations between negative perceptions of old age and perceived quality of life (QoL) among elderly people. It has also been suggested that a denial of aging mechanism is employed and might support ageist attitudes among private-sheltered housing tenants compared with elderly people who live in the community and experience intra-generational interactions. Therefore, we hypothesized that tenants of sheltered housing will report more ageist attitudes towards people of their own age, and report a lower QoL than elderly people who live in the community.Methods: The sample included 126 volunteers, aged between 64 and 94 years, who live in private-sheltered housing (n = 32) or in the community (n = 94). The participants completed the Fraboni scale of ageism, and a QoL Inventory (SF-36).Results: People, and men in particular, who live in sheltered housing, reported more intergenerational ageist attitudes than men and women who live in the community. Tenants in sheltered housing expressed lower evaluations of their mental health, but higher evaluations on “social functioning” (QoL scales). Women from sheltered housing reported better mental health than men. Gender and some QoL scales were associated with higher ageism.Conclusions: Differences in ageist attitudes between both dwelling places can be interpreted according to Social Identity Theory, which refers to the impact of the ingroup on social attitudes. Differences in QoL can be understood by the accessibility of social activities in private-sheltered housing. Gender differences in ageism and QoL can be explained by women's better social adjustment. Findings should be regarded with caution because of the small sample.
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Michelsen, Trond M., Anne Dørum, Claes G. Tropé, Sophie D. Fosså, and Alv A. Dahl. "Fatigue and Quality of Life After Risk-Reducing Salpingo-Oophorectomy in Women at Increased Risk for Hereditary Breast-Ovarian Cancer." International Journal of Gynecologic Cancer 19, no. 6 (July 2009): 1029–36. http://dx.doi.org/10.1111/igc.0b013e3181a83cd5.
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Background:Risk-reducing salpingo-oophorectomy (RRSO) is the safest intervention for prevention of ovarian cancer in women at increased risk for hereditary breast-ovarian cancer. Little is known about other effects of RRSO. The objective of this study was to investigate quality of life (QoL) and fatigue in a sample of women who had RRSO for increased cancer risk and to compare the findings with those of age-matched controls from the general population (NORM).Materials and Methods:In a cross-sectional follow-up mailed questionnaire design, 301 (67%) of 450 invited Norwegian women with RRSO attended. The questionnaire contained measures of QoL, fatigue, anxiety/depression, and body image, and questions about demography, lifestyle, and morbidity. The findings were compared with those of the NORM.Results:For RRSO women, mean age at survey was 53.7 years (SD, 9.2), mean age at RRSO was 48.4 years (SD 8.4), and median follow-up time was 5.0 years (range, 1-15 years). No clinically significant differences were observed between RRSO and NORM for any of the QoL or fatigue dimensions. In subgroup analyses of the RRSO group, no clinically significant differences in QoL and fatigue were observed between those who had surgery before or after age 50 years, or between BRCA1/2 carriers and women with unknown mutation statuses. Women who had cancer (32%), however, showed clinically significant lower levels of QoL and more fatigue than women without cancer.Conclusions:Women who had RRSO showed similar levels of QoL and fatigue as NORM. Women who had cancer before RRSO had lower levels of QoL and more fatigue.
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Pletikosić Tončić, Sanda, and Mladenka Tkalčić. "A Measure of Suffering in relation to Anxiety and Quality of Life in IBS Patients: Preliminary Results." BioMed Research International 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/2387681.
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Irritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) disorder with a severe impact on quality of life (QoL). We explored the relationship of a visual measure of suffering, the PRISM-RII, with quality of life (QoL) and anxiety measures in IBS patients. Participants were 44 IBS patients who completed several questionnaires and kept a symptom diary for two weeks. The measures used were PRISM-RII (self-illness separation (SIS); illness perception measure (IPM)); IBS-36 (IBS health related QoL); SF-36 (physical and mental health related QoL); State-Trait Anxiety Inventory (STAI-T); Visceral Sensitivity Index (VSI; GI-specific anxiety); and a symptom diary. SIS was negatively correlated to VSI, while IPM was negatively correlated to SIS and the physical component of SF-36 and positively to VSI and symptom severity. We found significant differences between participants who perceive their illness as small and those who perceive it as medium in SIS, symptom severity, VSI, and the mental component of SF-36. Participants, who perceived their illness as small, represented their illness as more distant, showed lower average symptom severity, and had lower GI-specific anxiety and higher QoL. The results indicate that IPM and SIS can be useful in discriminating patients with more prominent psychological difficulties and QoL impairment.
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Pruthi, Deep Shankar, Mushtaq Ahmad, Meenu Gupta, Saurabh Bansal, Vipul Nautiyal, and Sunil Saini. "Assessment of quality of life in resectable gastric cancer patients undergoing chemoradiotherapy as adjuvant treatmentLetter to the Editor." South Asian Journal of Cancer 07, no. 01 (January 2018): 16–20. http://dx.doi.org/10.4103/sajc.sajc_196_17.
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Abstract Introduction: Quality of life (QOL) is increasingly recognized as an important endpoint in cancer therapies. However, few data are available on QOL in patients who have received radiotherapy as adjuvant treatment for cancer stomach. Methods: Thirty patients who underwent curative resection were enrolled and received chemoradiotherapy (45 Gy in 25 fractions using three-dimensional conformal radiotherapy technique), together with 5-fluorouracil and leucovorin. The European Organization for Research and Treatment of Cancer QOL questionnaire C30 and STO Q22 was assessed at four time points: pre- and postchemoradiotherapy and at 1-month and 6-month follow-up. Results: Mean age of the patients was 54 years. Male:female ratio was 4:1. Stage II and Stage III disease was present in 60% and 30% of patients, respectively. All patients were able to complete the chemoradiotherapy protocol. Our study found out significant impairment in QOL for emotional functioning, fatigue, nausea and vomiting and dyspnea. Results showed that QOL levels decrease postchemoradiotherapy; however, QOL levels returned to baseline at 1-month and 6-month follow-up period. Conclusion: Chemoradiotherapy as adjuvant treatment for cancer stomach patients who have undergone resection with curative intent is a safe and well-tolerated regimen with respect to QOL.
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Artigas, Nathalie Ribeiro, Vera Lúcia Widniczck Striebel, Arlete Hilbig, and Carlos Roberto de Mello Rieder. "Evaluation of quality of life and psychological aspects of Parkinson's disease patients who participate in a support group." Dementia & Neuropsychologia 9, no. 3 (September 2015): 295–300. http://dx.doi.org/10.1590/1980-57642015dn93000013.
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Parkinson's disease (PD) is a neurodegenerative disorder that can dramatically impair patient quality of life (QoL). Objective: To analyze the QoL, motor capacity, depression, anxiety and social phobia of individuals who attended a patient support group (PSG) compared to non-participants. Methods: A cross-sectional study was performed. The sample consisted of 20 individuals with PD who attended a PSG and another 20 PD patients who did not attend a support group for PD patients, serving as the control group (nPSG). All patients answered questionnaires on motor capacity (UPDRS), QoL (Parkinson's Disease Questionnaire- PDQ-39), depression (Beck Depression Inventory), anxiety (Beck Anxiety Inventory) and social phobia (Liebowitz Social Anxiety Scale). To determine data distribution, the Shapiro-Wilk test was performed. For comparison of means, Student's t-test was applied. In cases of asymmetry, the Mann-Whitney test was employed. To assess the association between the scales, Pearson's correlation coefficient (symmetric distribution) and Spearman's coefficient (asymmetric distribution) were applied. For the association between qualitative variables, Pearson's Chi-squared test was performed. A significance level of 5% (p≤0.05) was adopted. Results: Individuals in the PSG had a significantly better QoL (p=0.002), and lower depression (p=0.026), anxiety (p<0.001) and social phobia (p=0.01) scores compared to the nPSG. Conclusion: The participation of PD patients in social activities such as support groups is associated with better QoL and fewer symptoms of depression, anxiety and social phobia.
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Smith, Sophia K., Deborah K. Mayer, Sheryl Zimmerman, Christianna S. Williams, Habtamu Benecha, Patricia A. Ganz, Lloyd J. Edwards, and Amy P. Abernethy. "Quality of Life Among Long-Term Survivors of Non-Hodgkin Lymphoma: A Follow-Up Study." Journal of Clinical Oncology 31, no. 2 (January 10, 2013): 272–79. http://dx.doi.org/10.1200/jco.2011.40.6249.
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Purpose Little is known about change in quality of life (QOL) among long-term cancer survivors. We examined change over time in QOL among long-term survivors of non-Hodgkin lymphoma and identified demographic, clinical, and psychosocial risk factors for poor outcomes. Methods Surveys were mailed to 682 lymphoma survivors who participated in a study 5 years earlier, when on average they were 10.4 years postdiagnosis. Standardized measures of QOL, perceptions of the impact of cancer, symptoms, medical history, and demographic variables were reported at both time points and examined using linear regression modeling to identify predictors of QOL over time. Results A total of 566 individuals participated (83% response rate) who were a mean of 15.3 years postdiagnosis; 52% were women, and 87% were white. One third of participants (32%) reported persistently high or improved QOL, yet a notable proportion (42%) reported persistently low or worsening QOL since the earlier survey. Participants who received only biologic systemic therapy reported improvement in physical health despite the passage of time. Older age, more comorbidity, and more or increasing negative and decreasing positive perceptions of cancer's impact were independent predictors of poor QOL. Lymphoma symptom burden, less social support, and having received a transplantation were related to negative perceptions of cancer's impact. Conclusion Moderate to severe symptom burden, limited social support, or having received a transplantation should alert the clinician to potential need for supportive services. Perceptions of cancer's impact are associated with QOL cross-sectionally and longitudinally; modifying these perceptions may thus provide a strategy for improving QOL.
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Johnson, Julene K., Jukka Louhivuori, Anita L. Stewart, Asko Tolvanen, Leslie Ross, and Pertti Era. "Quality of life (QOL) of older adult community choral singers in Finland." International Psychogeriatrics 25, no. 7 (April 11, 2013): 1055–64. http://dx.doi.org/10.1017/s1041610213000422.
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ABSTRACTBackground: Enhancing quality of life (QOL) of older adults is an international area of focus. Identifying factors and experiences that contribute to QOL of older adults helps promote optimal levels of functioning. This study examines the relationship between perceived benefits associated with choral singing and QOL among community-dwelling older adults.Methods: One hundred seventeen older adults who sing in community choirs in Jyväskylä, Finland, completed self-report measures of QOL (WHOQOL-Bref), depressive symptoms, and a questionnaire about the benefits of singing in choir. Correlational analyses and linear regression models were used to examine the association between the benefits of singing in choir and QOL.Results: Both correlation and regression analyses found significant relationships between the benefits of choral singing and three QOL domains: psychological, social relationships, and environment. These associations remained significant after adjusting for age and depressive symptoms. As hypothesized, older choral singers who reported greater benefits of choir singing had higher QOL in multiple domains. The older choral singers in the study also reported few symptoms of depression and high overall QOL and satisfaction with health.Conclusion: Results suggest that singing in a community choir as an older adult may positively influence several aspects of QOL. These results suggest that community choral singing may be one potential avenue for promoting QOL in older adults.
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Abraham, Sheela B., Aline Mazen Alsakka Amini, Noha Ehab Khorshed, and Manal Awad. "Quality of life of dentists." European Journal of Dentistry 12, no. 01 (January 2018): 111–15. http://dx.doi.org/10.4103/ejd.ejd_104_17.
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ABSTRACT Objective: An important determinant of job satisfaction and life fulfillment is the quality of life (QOL) of the individuals working in a particular field. Currently, in the United Arab Emirates (UAE), there is limited research pertaining to the QOL of dentists. The main objective of this study was to assess QOL of dentists in the UAE. Materials and Methods: The World Health Organization (WHO) QOL-BREF questionnaire (the World Health Organization abbreviated instrument for QOL assessment), which assesses QOL in physical, psychological, social, and environmental domains, was found to be a suitable instrument for use. A total of 290 questionnaires were distributed to general dental practitioners and specialists working in the private sector. The response rate was 46%. The completed questionnaires were coded and analyzed using the SPSS IBM software version 21. Results: QOL of specialists was significantly better than general practitioners (GPs) on all domains of the WHOQOL-BREF (P < 0.05). Married dentists had better QOL than singles on the social and environmental domains. Furthermore, specialists reported significantly better QOL compared to GPs after adjustment for sex, age, and marital status (P < 0.05) in the psychosocial and environmental domains. Conclusions: Among dentists who work in the UAE, QOL can be affected by several factors, one of them being whether dentist is a GP or a specialist.