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1

Chen, Li, I. Chen, Pei Chen, and Ping Huang. "Application of Butterfly Pea Flower Extract in Mask Development." Scientia Pharmaceutica 86, no. 4 (December 5, 2018): 53. http://dx.doi.org/10.3390/scipharm86040053.

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(1) Background: Clitoria ternatea (butterfly pea), a plant species belonging to the Leguminosae (Fabaceae) family, is useful for medical treatments and has been used in folk medicines and to cure different diseases. The antioxidation ability of the total phenolic compounds of butterfly pea is useful for preserving flavor, and colour and for preventing vitamin destruction in processed foods. In this study, a butterfly pea flower fermentation solution was added to cosmetics as a whiting ingredient. (2) Methods: After the phenolics, flavonoids and ascorbic acid content of the butterfly pea flower extraction had been determined, lactic acid bacteria fermented the extraction. The whitening and moisturizing effect was assayed by SSC3 and NF333 analyzers. (3) Results: This study demonstrated that the butterfly pea flower fermentation solution has free radical scavenging ability, a reducing power in high concentrations, a moisturizing effect, and a whiting effect. (4) Conclusions: The results showed that the butterfly pea flower fermentation solution not only inhibits redness, itching, allergies, and irritation to the skin, but also has antioxidation properties and promotes moisture retention and whitening effects, and the results increase as the concentration increases. Therefore, butterfly bean flowers may be suitable as a raw material for natural beauty care products.
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2

Burchmore, JJ, DA Pollard, MJ Middleton, JD Bell, and BC Pease. "Biology of four species of Whiting (Pisces: Sillaginidae) in Botany Bay, NSW." Marine and Freshwater Research 39, no. 6 (1988): 709. http://dx.doi.org/10.1071/mf9880709.

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Four species of whiting (Family Sillaginidae) were collected from Botany Bay, New South Wales, between 1977 and 1979: Sillago ciliata (sand whiting), S. maculata maculata (trumpeter whiting), S. robusta (stout whiting) and S. bassensis flindersi (eastern school whiting). Sillago ciliata was the most abundant species over-all. Sillago ciliata was caught in greatest numbers in Zostera seagrass and shallow sandy habitats, whereas S. m. maculata, S. robusta and S. b. flindersi were most abundant over deeper muddy and sandy habitats. Sillago ciliata and S. b. flindersi were present mainly as juveniles. Gonosomatic indices and gonadal maturity stages of S. ciliata and S. m. maculata peaked around February. These species probably spawn within the Bay. Length to caudal fork at first maturity was 24 cm for male and female S. ciliata, 19 cm for male and female S. m. maculata, 17 cm for male and 18 cm for female S. robusta, and 14 cm for male and female S. b. flindersi. Although all species fed mainly on polychaetes and crustaceans, there was little overlap in specific dietary items between species. Variations observed in diet were due to fish size and temporal and spatial habitat differences within and among species.
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3

Nadash, Pamela, Rani Snyder, and Eileen Tell. "Policy Series: Family Caregiving Policies: Where We Are Now." Innovation in Aging 5, Supplement_1 (December 1, 2021): 63. http://dx.doi.org/10.1093/geroni/igab046.242.

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Abstract This session reviews prospects for advancing family caregiving policy under the Biden Administration, by reporting on the RAISE (Recognize, Assist, Include, Support, and Engage) Family Caregivers Act, enacted in January 2018. The Act directs the Secretary of HHS to develop a national family caregiving strategy, and supports research and consensus-building activities, in collaboration with The John A. Hartford Foundation. It aims to identify actions that communities, providers, government, and others may take to recognize and support family caregivers. To this end, the Administration for Community Living (ACL) has convened an Advisory Council, comprising 15 voting members from various stakeholder groups, to guide the effort; the project also commissioned primary data collection on caregiver priorities and recommendations, using a Request for Information (RFI) in the Federal Register garnering roughly 1600 responses, 12 focus groups with diverse family caregivers, and listening sessions with stakeholder groups. Wendy Fox-Grage, of the National Academy on State Health Policy, which supports RAISE Act activities, will describe the project’s scope of work and activities to date. Pamela Nadash from the LeadingAge LTSS Center @UMass Boston, who leads the data analysis component, will present findings from the commissioned research, while Molly Evans, (MA Executive Office of Elder Affairs) will review the current state of state-level policies aimed at supporting family caregivers. The symposium will conclude with Grace Whiting, CEO of the National Alliance for Caregiving, who will present an advocate’s perspective on the status of family caregiving policy. Eileen Tell, of ET Consultants, will act as discussant.
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Prudencio, Gabriela, and Laura Gitlin. "Family Caregiver Assessments: What Have We Learned From Assessments Across Populations and Health Conditions?" Innovation in Aging 4, Supplement_1 (December 1, 2020): 689–90. http://dx.doi.org/10.1093/geroni/igaa057.2410.

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Abstract This symposium will bring together research on assessments of family caregivers for older individuals with different health conditions and discuss the components of effective assessments. Comprehensive characterizations of caregivers are essential due to an increase in the demand on caregivers, and how intense care contexts contribute to the caregiver’s decline in health and diminished capacity to provide quality care. According to Caregiving in the U.S. 2020 (n=1,400), only 13% of caregivers were asked by healthcare professionals what they needed to take care of themselves. Peer-reviewed studies have reported that caregivers are often reluctant to self-identify and to ask for the help that they need for themselves and those in their care. Since supports to caregivers have historically relied on this self-identification, the first presentation (Grace Whiting) will focus on the work NAC has done to build pathways between caregivers and supportive services to increase availability, accessibility, and patient-centeredness. The second presentation (Esther Friedman) will identify and discuss the barriers to fully incorporating family caregivers into the health care team, as well as the solutions for removing barriers. The next two presentations, respectively, will focus on characterizing the prevalence, burden, and unmet needs of caregivers of cancer patients (Erin Kent), and the unmet needs of families of adults with intellectual and development disabilities (Tamar Heller). The final presentation will explore caregiver readiness in dementia care using the Tailored Activity Program (TAP) and how TAP interventionists can use readiness scores to determine caregiver’s capacity (Katherine Marx).
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5

Williams, Richard. "Rituals in Families and Family Therapy. Edited by Evan Imber-Black, Janine Roberts and Richard Whiting. London: W. W. Norton. 1989. 414 pp. £24.50." British Journal of Psychiatry 156, no. 1 (January 1990): 140–41. http://dx.doi.org/10.1192/s0007125000060839.

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6

Roques, Severine, Clive J. Fox, Maria I. Villasana, and Ciro Rico. "The complete mitochondrial genome of the whiting, Merlangius merlangus and the haddock, Melanogrammus aeglefinus: A detailed genomic comparison among closely related species of the Gadidae family." Gene 383 (November 2006): 12–23. http://dx.doi.org/10.1016/j.gene.2006.06.018.

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7

Debenedetti, Ángela, Elena Madrid, María Trelis, Francisco Codes, Florimar Gil-Gómez, Sandra Sáez-Durán, and Màrius Fuentes. "Prevalence and Risk of Anisakid Larvae in Fresh Fish Frequently Consumed in Spain: An Overview." Fishes 4, no. 1 (February 21, 2019): 13. http://dx.doi.org/10.3390/fishes4010013.

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Anisakidosis is a fish-borne zoonosis caused by parasitic nematodes of the family Anisakidae, of which the species belonging to Anisakis simplex complex are the most representative. It is considered an emerging disease in Spain. The objective of this study is to analyse the presence of larvae in fish frequently consumed in Spanish supermarkets, inferring the risk of infection. In total 1,786 specimens of 9 different fish species, from two geographical origins (Atlantic and Mediterranean), acquired fresh and not eviscerated were examined for anisakid nematodes. Analysis showed that 33.7% of the samples were parasitized by Anisakis larvae. The horse mackerel (Trachurus trachurus) presented the highest total prevalence (66.0%), followed by the silver hake (Merluccius bilinearis) (59.5%), the mackerel (Scomber scombrus) (58.4%), the blue whiting (Micromesistius poutassou) (53.9%) and the European hake (Merlucius merlucius) (45.0%). In general, the prevalence was higher in Atlantic than in Mediterranean fish. In all the species analysed, a higher presence of the parasite was detected in the viscera than in the flesh, although in the most parasitized species a noteworthy prevalence and abundance was observed in the flesh. In conclusion, risk factors, like fish species and origin, should be considered by consumers, in addition of following the recommendations established by Commission Regulation (EU) No1276/2011 and the Spanish Royal Decree 1420/2006.
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8

Aung, Tim, Devita Surjana, and Manisha Singh. "Whitish genital lesions." Australian Journal of General Practice 50, no. 1-2 (February 1, 2021): 55–59. http://dx.doi.org/10.31128/ajgp-02-20-5247.

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9

Lücking, Robert. "Additions and Corrections to the Foliicolous Lichen Flora of Costa Rica. The Family Gyalectaceae." Lichenologist 31, no. 4 (July 1999): 359–74. http://dx.doi.org/10.1006/lich.1999.0205.

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AbstractThis paper provides a revision of the foliicolous representatives of the Gyalectaceae in Costa Rica. Five species of Coenogonium and 13 of Dimerella are distinguished. Coenogonium interplexum, C. interpositum, C. leprieurii, C. linkii and Dimerella vezdana are ubiquitous as to the choice of their substratum, whereas C. moniliforme and Dimerella lutea are facultatively foliicolous. The remainder are typically foliicolous taxa but may occasionally be found on bark. The following species are for the first time reported as foliicolous from Costa Rica: Coenogonium interplexum, C. interpositum, C. leprieurii, C. moniliforme, Dimerella fallaciosa, D lisowskii, and D. aff. pilifera. Three new species are described: Dimerella isidiifera sp. nov. with disciform isidia, D. subzonatasp. nov. with small, bright yellow, dentate apothecia and a whitish prothallus, and D. siquirrensis sp. nov. with large, orange apothecia and a thin whitish prothallus. A key is presented for neotropical foliicolous Gyalectaceae, and notes on the distribution and ecology of the species are given.
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10

Milton, DA. "Genetic-Evidence for Sympatric Differentiation Between 2 Color Morphs of the Skink Egernia-Whitii." Australian Journal of Zoology 38, no. 2 (1990): 117. http://dx.doi.org/10.1071/zo9900117.

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The viviparous skink Egernia whitii is dimorphic for dorsal colour pattern. Both patterned and plain morphs coexist throughout the species' range. Adults live in family groups beneath exfoliating granite rocks. The closely related E. modesta also coexists in similar habitats in the northern part of the range of E. whitii. The plain E. whitii morph is intermediate in colour pattern between patterned E. whitii and E. modesta. Three populations of E. whitii and two populations of E. modesta were examined electrophoretically to assess the status of the plain morph of E. whitii. There were no fixed differences between the two morphs of E. whitii at any of the 55 loci examined, and loci polymorphic in both rnorphs of E. whitii showed no evidence of linkage disequilibria. Although heterozygosity values (H=0.017�0.002) and the level of polymorphism (P 0.95=0.015) were low, there were highly significant allele frequency differences between sympatric samples of the two morphs of E. whitii. This indicated that the two morphs were conspecific, yet they were not interbreeding at random. The established frequency of gene exchange between the two colour morphs in the three populations sampled varied from 3.6 to 6 individuals per generation. Reproductive data confirmed that both colour morphs of E. whitii produced young of the same dorsal colour pattern as their own in much greater frequency than random. However, females of both colours can and do breed with males of the other colour in very low frequency. Analysis of the lateral colour pattern of the two E. whitii morphs and E. modesta suggests that the colour patterns of the two E. whitii morphs are very similar, yet differ slightly from the colour pattern of E. modesta in the region of geographic overlap of these species. These results suggest that behavioural or microhabit differences between the two morphs may be involved in mate recognition.
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11

ARDILA-CAMACHO, ADRIAN, and CALEB C. MARTINS. "First record of spongillaflies (Neuroptera: Sisyridae) from Colombia." Zootaxa 4276, no. 1 (June 9, 2017): 129. http://dx.doi.org/10.11646/zootaxa.4276.1.8.

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The family Sisyridae (spongillaflies) is a small group of neuropterans distributed in all Biogeographic realms (Cover & Resh 2008). As in Nevrorthidae, Sisyridae is distinguished among other Neuroptera families by their strictly aquatic larvae (Wichard et al. 2002). The phylogenetic relationships of Sisyridae have been controversial i.e. the family was recovered at different positions within the Neuropterida phylogeny as a basal group among members of Neuroptera or whitin the suborder Hemerobiiformia with a very variable placement (Randolf et al. 2013). Currently the species richness of this group reaches 70 representatives in four genera, namely Climacia McLachlan, 1869 (New World), Sisyra Burmeister, 1839 (cosmopolitan), Sisyrina Banks, 1939 (Africa, Asia and Australia), and Sisyborina Monserrat, 1981 (endemic to Africa) (Parfin & Gurney 1956; Cover & Resh 2008).
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12

Moon, Sung Ho, Euihyun Kim, Hye-In Kim, Soo-Yun Kim, Hyo-Hyun Seo, Jeong Hun Lee, Min-Sup Lee, Seung-Ki Lee, Sang Hyun Moh, and Seunghee Bae. "Skin-Whitening Effect of a Callus Extract of Nelumbo nucifera Isolate Haman." Plants 12, no. 23 (November 21, 2023): 3923. http://dx.doi.org/10.3390/plants12233923.

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The sacred lotus (Nelumbo nucifera Gaertn. Isolate Haman, in the family Nelumbonaceae) used in this study originated from the Haman region of Korea, and lotus seeds dating back to the Goryeo Dynasty (650–760 years ago) were accidentally discovered. Lotus is known to possess antioxidant, anti-inflammatory, and soothing properties. Instead of using the lotus alone, we obtained extracts using Haman region lotus-derived callus (HLC), which allowed for a controlled, quantitative, and infinite supply. Based on the reported effects of the lotus, we formulated a hypothesis to investigate the skin-whitening effect of the HLC extract (HLCE). The HLCE was first obtained by extraction with distilled water and using 5% propanediol as a solvent and subsequently verified for the whitening effect (melanin content tests) using mammalian cells in vitro. Its efficacy at the molecular level was confirmed through real-time polymerase chain reaction (PCR) using melanin-related genes. Furthermore, clinical trials with 21 volunteers confirmed the significant whitening effect of cosmetics containing the HLCE. In conclusion, we found that the HLCE not only has anti-inflammatory, antioxidant, and skin-soothing properties but also plays an essential role in skin whitening. Therefore, we propose that the HLCE has the potential to become a new raw material for the cosmetic industry.
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13

Khan, AK, SA Khan, Na Muhammad, No Muhammad, J. Ahmad, H. Nawaz, A. Nasir, S. Farman, and S. Khan. "Mutation in Phospholipase C, δ1 (PLCD1) gene underlies hereditary leukonychia in a Pashtun family and review of the literature." Balkan Journal of Medical Genetics 21, no. 1 (October 29, 2018): 69–72. http://dx.doi.org/10.2478/bjmg-2018-0001.

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AbstractHuman hereditary leukonychia is a rare nail disorder characterized by nail plates whitening on all finger and toe nails. Inheritance pattern is both autosomal dominant and recessive. To date, the only gene, phospholipase C, δ1 (PLCD1), on chromosome 3p22.2 has been reported to be involved in hereditary leukonychia. In the present study, a family of Pakhtun ethnicity, carrying leukonychia phenotype was investigated. The family inherited the phenotype in an autosomal dominant fashion. Affected individuals exhibited characteristic features of hereditary leukonychia with involvement of nails on both the hands and feet. Sequence analysis of DNA detected a p.Cys209Arg mutation, reported for the first time in a Pakistani Pashtun family.
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14

Calvopiña, Manuel, and Jacob Bezemer. "Case Report: Evidence of Tungiasis in the Amazon Rain Forest of Ecuador." American Journal of Tropical Medicine and Hygiene 105, no. 3 (September 15, 2021): 698–700. http://dx.doi.org/10.4269/ajtmh.21-0207.

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ABSTRACT. Tungiasis occurs in tropical and subtropical areas in Central and South America and sub-Saharan Africa and is a Neglected Tropical Disease. We diagnosed three cases of tungiasis in a Dutch family visiting indigenous communities in the Amazon basin of Ecuador. Eight days after returning, they presented papular, pruritic, and painful lesions on the feet, with a whitish halo and a blackish central point with abundant whitish eggs upon extraction. For the first time, we demonstrate that Tunga spp. transmission is present in remote indigenous communities in the Amazon rainforest of Ecuador. It will be important to investigate the occurrence of tungiasis and associated morbidity among local inhabitants and consider prevention measures among locals and travelers to these areas.
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Mohamedkhair, Suha Gafar, Lafi Munira, Ahmed Mohammed Alamin, and Pramon Viwattanakulvanid. "Factors Associated with Adverse Events Related to Topical Whitening Products Used among College Female Students in Sudan." Contagion: Scientific Periodical Journal of Public Health and Coastal Health 6, no. 1 (January 22, 2024): 1. http://dx.doi.org/10.30829/contagion.v6i1.17927.

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<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em>This study aimed to explore the factors associated with adverse events related to topical whitening products used and to explore the reasons for using topical whitening products among female students in Sudan. A cross-sectional study was conducted from September to October 2023 in Sudan. The Medicine and Pharmacy programs were purposively selected as the study area. The total sample size was 208 participants. The self-administered questionnaire was constructed with a total of seventeen questions. For data analysis, we performed descriptive statistics analysis, bivariate analysis with simple logistic regression, and multivariable analysis with binary logistic regression presenting with adjusted odds ratio (AOR) and 95% confidence interval (95% CI). The results imply that students with middle household income were 93% less likely to get adverse events compared to those students with low household income with p-value = 0.030 (AOR: 0.07, 95% CI: 0.06 ,0.77). Students who have tested the topical whitening products before using them were 99.9% less likely to get adverse events compared to those who do not test, with p-value = &lt;0.001 (AOR: 0.001, 95% CI: 0.001,0.00). Students who shared whitening products with family/friends were 89% less likely to get adverse events than those who do not share with p-value = 0.009 (AOR: 0.11, 95% CI: 0.021, 0.57). Furthermore, students who used whitening products with added water or other agents to whitening products were 95% less likely to get adverse events compared to those who did not use with p-value = 0.038 (AOR: 0.05, 95% CI:0.02, 0.84). The top two reasons respondents for using topical whitening products were acne (26.9%) and for beautification (24.5%). The study suggested the local government and health sectors should educate and raise the awareness of the safety of whitening products use among female students.</em></p><p><em><br /></em></p></td></tr></tbody></table></div><strong><em>Keywords: Adverse events, female students, Sudan, Whitening topical products</em></strong>
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JOSHI, Santosh, Udeni JAYALAL, Soon-Ok OH, Young Jin KOH, Thi Thuy NGUYEN, Nguyen Anh DZUNG, and Jae-Seoun HUR. "New species and new records in the family Graphidaceae (Ascomycota: Ostropales) from Vietnam." Lichenologist 45, no. 5 (August 23, 2013): 599–609. http://dx.doi.org/10.1017/s002428291300025x.

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AbstractAcanthothecis salazinica and Diorygma archeri are described from Vietnam. The former is characterized by having a leprose thallus, creamish to whitish, entire, epruinose labia, a slit-like disc, a hyaline to brown, entire proper exciple, warty periphysoids, 8-spored asci, and 28–30-loculate, hyaline, I− ascospores, 70–120×7–14 µm in size. The latter has a greenish grey thallus, a poorly developed, hyaline to pale or brownish proper exciple, 1-spored asci, hyaline, muriform ascospores, and produces protocetraric acid. Acanthothecis corcovadensis, Diorygma erythrellum, D. junghuhnii, D. macgregorii, Platygramme platyloma, Pliariona montagnei and Thecaria quassiicola are recorded for the first time from the country.
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Wu, Hao, Yunpeng Lian, Bin Liu, Yanling Ren, Peisheng Qin, and Fuchang Huang. "Thermotunica guangxiensis gen. nov., sp. nov., isolated from mushroom residue compost." International Journal of Systematic and Evolutionary Microbiology 64, Pt_5 (May 1, 2014): 1593–99. http://dx.doi.org/10.1099/ijs.0.057562-0.

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A novel thermophilic actinomycete, designated AG2-7T, was isolated from mushroom residue compost in Guangxi University, Nanning, China. The strain grew optimally at 45–60 °C, at pH 7.0 and with 0–3.0 % (w/v) NaCl. Vegetative mycelia were branched and whitish to pale yellow without fragmentation. Aerial mycelium was abundant, whitish and differentiated into long chains of spores, with a membranous structure or tunica partially covering the surface of aerial hyphae. The non-motile spores were oval in shape with a ridged surface. Strain AG-27T contained meso-diaminopimelic acid as the diagnostic diamino acid, and the whole-cell sugars were galactose and ribose. Major fatty acids were iso-C16 : 0 (27.51 %), iso-C17 : 0 (10.47 %) and anteiso-C17 : 0 (12.01 %). MK-9(H4) was the predominant menaquinone. The polar phospholipids were diphosphatidylglycerol, ninhydrin-positive glycophospholipid, phosphatidylinositol, phosphatidylinositol mannoside, phosphatidylethanolamine, phosphatidylmethylethanolamine, an unknown phospholipid and unknown glucosamine-containing phospholipids. The G+C content of the genomic DNA was 63.6 mol%. 16S rRNA gene sequence analysis showed that the organism belonged to the family Pseudonocardiaceae , suborder Pseudonocardineae and showed more than 5 % divergence from other members of the family. Based on the phenotypic and phylogenetic data, strain AG2-7T represents a novel species of a new genus in the family Pseudonocardiaceae , for which the name Thermotunica guangxiensis gen. nov., sp. nov. is proposed. The type strain of the type species is AG2-7T ( = ATCC BAA-2499T = CGMCC 4.7099T).
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18

Lin, Yi Yang, and Lynette Wei Yi Wee. "Pediatric Leukonychia Totalis: A Case Report and Review of Literature." Asian Journal of Pediatric Dermatology 2, no. 1 (January 2024): 15–19. http://dx.doi.org/10.4103/ajpd.ajpd_2_24.

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Abstract Leukonychia totalis, a rare condition characterized by complete whitening of the nails, presents an intriguing diagnostic challenge, particularly when it occurs in pediatric patients without an established family history. We discuss a case of an 8-year-old boy with leukonychia totalis, involving all fingernails but sparing his toenails, in the absence of familial predisposition. This report aims to discuss the etiopathogenesis, differential diagnosis, and diagnostic approach in pediatric leukonychia totalis.
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Won, Yu Rim, Kyung Jong Won, Do Yoon Kim, Mi Jung Kim, Bok Sil Hong, and Hwan Myung Lee. "Chemical Composition of Impatiens textori Miq. Flower Absolute and Its Potential Wound Repair and Anti-Melanogenesis-Promoting Activities in Skin Cells." Pharmaceuticals 15, no. 11 (November 13, 2022): 1397. http://dx.doi.org/10.3390/ph15111397.

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Impatiens textori Miq. (ITM; family Balsaminaceae) is a traditional medicinal plant with many biological activities, which include anti-allergic, anti-inflammatory, and anti-pruritic properties. However, it remains to be determined whether ITM affects biological activities in the skin. Thus, we investigated the effects of ITM flower absolute (ITMFAb) extract on the biological activities of skin, especially those related to skin wound repair and whitening. ITMFAb was extracted with hexane, and its composition was determined through GC/MS. The biological activities of ITMFAb on HaCaT keratinocytes and B16BL6 melanoma cells were analyzed using a water-soluble tetrazolium salt, 5-bromo-2′-deoxyuridine incorporation, a Boyden chamber, an ELISA, a sprouting assay, and by immunoblotting. These analyses were performed in a range of ITMFAb concentrations that did not inhibit the viability of the cells (HaCaT, ≤400 µg/mL; B16BL6, ≤200 µg/m). Forty components were identified in ITMFAb. ITMFAb stimulated proliferation, migration, sprout outgrowth, and type I and IV collagen synthesis and upregulated the activations of ERK1/2, JNK, p38 MAPK, and AKT in HaCaT cells. In addition, ITMFAb attenuated the serum-induced proliferation of B16BL6 cells. ITMFAb inhibited melanin synthesis, tyrosinase activity, and expressions of MITF and tyrosinase in α-MSH-exposed B16BL6 cells. These findings indicate that ITMFAb has beneficial effects on wound repairing and whitening-linked responses in the skin and suggest the potential use of ITMFAb as a natural material for the development of skin wound repair and whitening agents.
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Ludwig, Lars R., Gintaras Kantvilas, Andy R. Nilsen, David A. Orlovich, Yoshihito Ohmura, Tina C. Summerfield, Karina Wilk, and Janice M. Lord. "A molecular-genetic reassessment of the circumscription of the lichen genus Icmadophila." Lichenologist 52, no. 3 (May 2020): 213–20. http://dx.doi.org/10.1017/s0024282920000122.

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AbstractThe circumscription of the lichenized ascomycete genus Icmadophila Trevis. in the family Icmadophilaceae Triebel was investigated. Sequences of the internal transcribed spacer (ITS) region and large subunit of nuclear ribosomal DNA (nuLSU) were generated for the five Icmadophila species and additional members of Icmadophilaceae from the genera Dibaeis, Endocena, Knightiella, Siphula, Siphulella and Thamnolia. Phylogenetic analyses indicate that three Icmadophila species are closely related: the type, I. ericetorum (L.) Zahlbr., which is widespread in Eurasia and North America, I. aversa (Nyl.) Rambold & Hertel from Central and South America, and I. japonica (Zahlbr.) Rambold & Hertel, which is restricted to Far East Russia and Japan. The genus Knightiella Müll. Arg. is reinstated to accommodate I. splachnirima (Hook.f. & Taylor) D. J. Galloway emend. L. Ludw., which occurs in New Zealand and Australia. Two further species of Knightiella, K. eucalypti (Kantvilas) Kantvilas and K. queenslandica Kantvilas, are found to be unrelated to K. splachnirima, and are accommodated in two newly described genera, Knightiellastrum and Siphulopsis respectively. Knightiellastrum L. Ludw. & Kantvilas is characterized by a squamulose, erhizinate, whitish to pale grey thallus with a green, coccoid photobiont and by containing thamnolic acid. Siphulopsis Kantvilas & A. R. Nilsen is similarly characterized by an erhizinate, whitish to pale grey thallus, with a green, coccoid photobiont and containing thamnolic acid, but is instead fruticose. This study reveals considerable diversity within Australasian Icmadophilaceae; ongoing work in the Southern Hemisphere and tropical regions may reveal additional species in this family and clarify the relationships of these newly described genera.
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Turki, Ola Hameed, and Zainab Juma Jafar. "Whitening Effect of Juglans regia Dry Husk Extract on Primary and Permanent Teeth." International Journal of Biomaterials 2023 (July 21, 2023): 1–6. http://dx.doi.org/10.1155/2023/1037661.

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Walnut is a common member of the family Juglandaceae. Recently, the evaluation of the phenolic content and antioxidant activity of the parts of walnut has received increased interest. Many reasons are responsible for teeth discolouration because teeth can absorb ingredients from tea, coffee, and food. Stains from these ingredients could stay in the porous enamel layer. Traditional whitening chemicals have some side effects, the most common of which is tooth sensitivity and mild or moderate gingival irritation. The aims of this comparative experimental study were to evaluate the whitening effect of Juglans regia dry husk extract and compare it with that of traditional prophylactic pumice. Forty human teeth were collected. Amongst these teeth, 20 were permanent, and the other 20 were primary. Each group was randomly divided into a study group (treated with dry husk extract) and a control group (treated with traditional pumice). Tooth colour was measured with Easy VitaShade Advanced 4.0, and the readings of lightness, chroma, and hue ( a ∗ represents the green to red axis and b ∗ represents the blue to yellow axis) were documented for each tooth before and after polishing. A statistical analysis was performed using the Statistical Package for Social Science (version 22; Chicago, Illinois, USA). Data were analysed using Shapiro–Wilk, Wilcoxon sum rank, and Wilcoxon signed rank tests, and the level of significance was set to 0.05. A normality test was conducted using the Shapiro–Wilk test, and it showed that the colour variables were not normally distributed. With regard to tooth lightness, significant differences were observed in the primary and permanent teeth and Juglans regia exerted a much better whitening effect than pumice at p < 0.05 . This study supports the use of Juglans regia dry husk extract in dentistry as a natural product with a whitening effect. It has utilisation potential in dentistry due to its beneficial properties and highly active components.
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Batiha, Gaber El-Saber, Hazem M. Shaheen, Esraa A. Elhawary, Nada M. Mostafa, Omayma A. Eldahshan, and Jean-Marc Sabatier. "Phytochemical Constituents, Folk Medicinal Uses, and Biological Activities of Genus Angelica: A Review." Molecules 28, no. 1 (December 28, 2022): 267. http://dx.doi.org/10.3390/molecules28010267.

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Genus Angelica is one of the widely distributed and well-known genera of family Umbelliferae. It is utilized mainly by Chinese and Korean populations especially in their folk medicine. Angelica comprises a lot of medicinally important phytoconstituents such as coumarins, furanocoumarins, flavonoids, essential oils, verbascosides, polysaccharides, etc. Members of this genus play important roles, namely antioxidant, anti-inflammatory, anti-microbial, anti-diabetic, skin-whitening, cytotoxic, hepatoprotective, and many others. This review draws attention to many species of genus Angelica with much focus on A. dahurica being one of the highly medicinally used species within this genus.
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Zhang, Tao, Chang Liu, Jingliang He, Yanwei Kang, Feng Wang, and Shaowei Li. "Cornea guttata associated with special phenotypic variants of granular corneal dystrophy type 2 in a Chinese family." European Journal of Ophthalmology 30, no. 3 (March 14, 2019): 469–74. http://dx.doi.org/10.1177/1120672119832176.

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Purpose: The aim of this study was to analyze the relevant gene mutations in a Chinese family with special phenotypic variants of granular corneal dystrophy type 2 with cornea guttata. Methods: A total of 11 individuals from the affected family underwent complete ophthalmic examination. Genomic DNA was extracted from peripheral leukocytes of affected and unaffected family members. High-throughput sequencing was performed to screen for mutations in 290 genes associated with inherited ophthalmic diseases. Results were validated by bidirectional Sanger sequencing. Results: An Arg124His (R124H) mutation of the transforming growth factor beta-induced gene was identified in three members of the affected family: the proband (II-1), his mother (I-2), and his son (III-1). The eyes of the proband and his mother had bilateral superficial whitish ring patches with clear centers occupying their central corneas and appeared to be discoid or ring shaped. In addition, specular microscopic examination showed the presence of dark, round bodies. In vivo confocal microscopy showed some hyporeflective round images (cornea guttata), containing occasionally central highlight, in the proband, his mother, and one of his elder sisters. Conclusion: We report, for the first time, atypical granular corneal dystrophy type 2 with cornea guttata associated with a single R124H mutation in a Chinese family. Our findings emphasize that genotyping is essential for the accurate diagnosis and classification of granular corneal dystrophy type 2.
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Atick, Joseph J., and A. Norman Redlich. "What Does the Retina Know about Natural Scenes?" Neural Computation 4, no. 2 (March 1992): 196–210. http://dx.doi.org/10.1162/neco.1992.4.2.196.

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By examining the experimental data on the statistical properties of natural scenes together with (retinal) contrast sensitivity data, we arrive at a first principle, theoretical hypothesis for the purpose of retinal processing and its relationship to an animal's environment. We argue that the retinal goal is to transform the visual input as much as possible into a statistically independent basis as the first step in creating a redundancy reduced representation in the cortex, as suggested by Barlow. The extent of this whitening of the input is limited, however, by the need to suppress input noise. Our explicit theoretical solutions for the retinal filters also show a simple dependence on mean stimulus luminance: they predict an approximate Weber law at low spatial frequencies and a De Vries-Rose law at high frequencies. Assuming that the dominant source of noise is quantum, we generate a family of contrast sensitivity curves as a function of mean luminance. This family is compared to psychophysical data.
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Kaushik, Neha, June-Hyun Kim, Linh Nhat Nguyen, Nagendra Kumar Kaushik, and Kyung-A. Choi. "Characterization of Bioactive Compounds Having Antioxidant and Anti-Inflammatory Effects of Liliaceae Family Flower Petal Extracts." Journal of Functional Biomaterials 13, no. 4 (December 8, 2022): 284. http://dx.doi.org/10.3390/jfb13040284.

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Beneficial natural products utilized in cosmetics formulation and pharmaceutical applications are of enormous interest. Lily (Lilium) serves as an essential edible and medicinal plant species with wide classification. Here, we have performed the screening of various extracts that were prepared from flower petals grown from the bulbs of eight Lilium varieties, with a viewpoint to their applicability as a viable source of natural anti-inflammatory and antioxidants agent. Interestingly, our findings indicated that all ethanol and water extracts exhibited a substantially differential spectrum of antioxidant as well as anti-inflammatory properties. Specifically, Serrano showed a close similarity among ethanol and water extracts among all tested lily petal extracts. Therefore, to obtain a detailed analysis of chemical compounds, liquid chromatography–mass spectroscopy was performed in ethanolic and water extracts of Serrano petals. Together, our preliminary results indicated that lily petals extracts used in this study could serve as a basis to develop a potential new whitening agent with powerful antioxidant and anti-inflammatory properties for medicinal, functional food, and cosmetic applications.
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Wawrzyńczak, Agata. "Cosmetic and Pharmaceutic Products with Selected Natural and Synthetic Substances for Melasma Treatment and Methods of Their Analysis." Cosmetics 10, no. 3 (June 2, 2023): 86. http://dx.doi.org/10.3390/cosmetics10030086.

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Melasma is a fairly common condition that is the result of hyperpigmentation caused by increased melanin secretion. In the course of melasma, certain areas of the skin become darker than the rest of the epidermis. Although the pathogenesis remains incompletely clarified, several contributing factors have been identified, namely exposure to ultraviolet and visible light, family predisposition, pregnancy, and the use of exogenous hormones. Since current beauty standards associate healthy skin with its flawless and uniform color, people strive to eliminate any unaesthetic discoloration. Cosmetic and pharmaceutical products containing active substances with a whitening effect then become helpful. The most commonly used for this purpose are hydroquinone, arbutin, retinoids, organic acids (e.g., kojic, azelaic, and ellagic), and vitamins (B3, C, and E). However, the undesirable side effects they cause and the drive to replace synthetic chemicals with their natural counterparts have resulted in numerous reports on extracts of natural origin that exhibit skin-whitening effects. The purpose of this paper is to review the most recent scientific literature, which presents active substances of natural and synthetic origin with potential for the treatment of melasma. In addition, analytical techniques that can be used for qualitative and quantitative analysis of these substances present in cosmetic and pharmaceutical products will also be presented.
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VOLYNKIN, ANTON V. "Siccia imana, a new species from Rwanda (Lepidoptera: Erebidae: Arctiinae)." Zootaxa 4571, no. 2 (March 26, 2019): 285. http://dx.doi.org/10.11646/zootaxa.4571.2.11.

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The genus Siccia Walker, 1854 is a member of the subtribe Cisthenina Bendib & Minet of the tribe Lithosiini Billberg (family Erebidae Leach, subfamily Arctiinae Leach) being widely distributed in the Afrotropics. Members of the genus are small or medium-sized moths with similar external appearance (whitish or grey wing coloration with blackish pattern consisting of spots and transverse lines). The check-list of the genus was provided by Kühne (2007), two additional species were described by Ivinskis & Saldaitis (2008). Currently the genus includes 20 valid species with very different male and female genitalia structures, and the generic and subgeneric structure of this group needs revision (Volynkin & László, in prep.).
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Anand, P., J. Michael Israel, Ankit Bachhawat, Vandana Garima Gujadhur, Chriss K. George, and P. U. Antony. "A Comparative Study on Mite Infected Coconut Trees in Christ College Campus." Mapana - Journal of Sciences 5, no. 1 (August 29, 2006): 60–64. http://dx.doi.org/10.12723/mjs.8.8.

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Cocon ut mite Aceno (Eriophyes) guerreronis (Keifer) Of the family Eriophyi±e has been posing serious problems to the production OF coconut in Keralc from 1997 onwards. From an infestation which was confined to a few plantations in Ermkukrn District in 1997, the pest has now spread extensively in the State. The attack has caused drastic reduction in coconut production, pioying havoc to the coconut based economy Of Kerala. Of lofe the problem is widespread in many pans o/ Karnataka Ond the whole of south India. Coconut perianth mite is a microscopic, whitish organism, 0.20 - 0.25 mm long and cylindrical. The species and genus is distinguished by the presence Of c median pit just posterior to the prodorsa' shield.
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de Borja Domínguez-Serrano, Francisco, Marina Soto-Sierra, María González-del Pozo, María José Morillo-Sánchez, Manuel Ramos-Jiménez, Mireia López-Domínguez, Beatriz Ponte-Zuñiga, Guillermo Antiñolo-Gil, and Enrique Rodríguez de la Rúa-Franch. "X-linked Retinoschisis Associated with Retinitis Punctata Albescens Caused by a Mutation in the RS1 Gene: A Family Study." Open Ophthalmology Journal 15, no. 1 (October 5, 2021): 201–5. http://dx.doi.org/10.2174/1874364102115010201.

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Purpose: To describe the clinical and genetic characteristics (mutation in RS1 gene) of a Spanish family with X-linked retinoschisis (XLRS) associated with retinitis punctata albescens (RPA). Methods: The detailed ophthalmological examination included best corrected visual acuity (BCVA), colour and autofluorescence photography, fluorescein angiography, optical coherence tomography and electrophysiology tests. A next-generation sequencing (NGS) strategy was applied to the index patient, and then sequenced in an Illumina NextSeq500 system. Candidate variants considered to be disease-causing in the patient were confirmed and segregated in the family by Sanger sequencing. Results: We have studied three siblings of 54, 59 and 50 years old. Two of them presented with macular foveoschisis and a whitish mottling of the pigment epithelium in the peripheral and equatorial retina, while the other had macular atrophy. Electroretinography revealed a reduced b-wave, while a-wave remained unchanged. Mutation in RS1 (c.98G>A; p.Trp33*) was identified as the cause of the disease. Conclusion: XLRS is a genetic disease that leads to irreversible visual loss. We describe an unusual phenotype manifestation of a known mutation.
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Lee, Min-Kyeong, Heeyeon Ryu, Ji Yun Lee, Hyeon Hak Jeong, Jiwon Baek, Ji Yun Van, Myeong-Jin Kim, Won-Kyo Jung, and Bonggi Lee. "Potential Beneficial Effects of Sargassum spp. in Skin Aging." Marine Drugs 20, no. 8 (August 22, 2022): 540. http://dx.doi.org/10.3390/md20080540.

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Seaweeds are receiving much attention as a rich source of bioactive compounds with cosmeceutical potential. Recent studies have revealed that Sargassum spp., a genus of brown algae in the family Sargassaceae, has multiple functions in preventing and improving skin aging. Sargassum spp. contains many bioactive compounds, such as fucoidan, fucoxanthin, terpenoids, flavonoids, and meroterpenoids. These Sargassum spp. extracts and derivative compounds have excellent potential for skincare, as they exhibit skin health-promoting properties, including antioxidants, anti-inflammation, whitening, skin barrier repair, and moisturizing. Therefore, searching for bioactive compounds in marine resources such as Sargassum spp. could be an attractive approach to preventing and improving skin aging. The current review focused on the various biological abilities of Sargassum extracts or derived compounds for anti-skin aging.
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Pal, Anjila, Alok Atreya, Nabina Maharjan, Monika Mahat, and Rabin Bom. "Human Ocular Thelaziasis: A Case Report." Journal of Nepal Medical Association 59, no. 242 (October 23, 2021): 924–26. http://dx.doi.org/10.31729/jnma.6447.

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Thelaziasis is a zoonotic disease which affects the eye of domestic and wild carnivores caused by the nematode Thelazia. It is transmitted to humans by secretophagous arthropod-borne zoophilic nonbiting flies of the family Drosophilidae. Human thelaziasis is rare and occurs in poor socio-economic families of the rural locations where people live in close proximity with animals. A one and halfyear-old was presented to the outpatient ophthalmology clinic after her mother noticed a whitish, thread-like worm in her right eye. A total of four worms were mechanically removed from her right eye. All the collected worms were gravid female nematodes of Thelazia species. The present case of human ocular thelaziasis from Palpa, Nepal is presented for its rarity.
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Barbhuiya, Hussain Ahmed. "Neotypification of Brachyscome assamica C.B. Clarke (Asteraceae)." Phytotaxa 164, no. 3 (April 8, 2014): 200. http://dx.doi.org/10.11646/phytotaxa.164.3.6.

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Brachyscome assamica C.B. Clarke (1876: 40) is a small shrubby herb, restricted to Assam State of northeast India and it is the only known species of the genus Brachyscome Cassini (1816: 199) occurring in India. It can be readily recognized by its 1–2-seriate elliptic involucral bracts with scarious margins, longer, whitish, violet-tinged ligules, beaked achenes, and the absence of a pappus. Clarke (1876) described the species based on material seen at the Calcutta Herbarium (CAL) collected from Dihing River Rocks, Namsang, in Upper Assam, India. Hooker (1881: 249) mentioned that he knew “nothing of this plant, which exists only in the Calcutta Herbarium, where Clarke described it”. Hajra (1995: 102), in revision of the family Asteraceae in “Flora of India”, indicated that no relevant material could be found at the CAL.
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Chrishantha C, Joybell, Darshini Indhu E, and Shiny Sheeba Jeba J. "Say Goodbye to Bad Breath and Hello to Confidence - Unlocking the World of Mouth Rinse." International Journal of Current Research and Review 15, no. 12 (2023): 01–03. http://dx.doi.org/10.31782/ijcrr.2023.151201.

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Fresh breath is a sign of good oral hygiene, not to mention, family and friends appreciate it. Luckily, we have many options to choose from to help us keep that breath smelling great. Some people use mouthwash to battle bad breath, while others use it to prevent tooth decay and gingivitis. Mouthwash also helps with overall tooth and gum health and can even help whiten teeth. Mouthwash, otherwise called an oral rinse, does not substitute brushing and flossing. It is a liquid product used to rinse the teeth and gums. With there being so many different types of mouthwashes, this review article throws light on the various available mouth washes for children.
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YOSUVA, MARIASINGARAYAN, HSUAN-CHING HO, DANARAJ JEYAPRAGASH, and AYYAPPAN SARAVANAKUAMR. "Parapercis annamalai sp. nov., a new sandperch from southwestern India (Family Pinguipedidiae)." Zootaxa 4786, no. 4 (June 4, 2020): 555–64. http://dx.doi.org/10.11646/zootaxa.4786.4.7.

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A new sandperch is described from 3 specimens from off Parangipettai, southeastern India. It can be separated from its congeners in having a combination of dorsal-fin rays V, 21‒22; anal-fin rays I, 17‒18; pectoral-fin rays 17‒18; pored lateral-line scales 53‒54; median predorsal scales 7; transverse scale rows 4/13; gill rakers on 1st gill arch 15‒17; single row of stout teeth on vomer; no teeth on palatine; 3 pairs of enlarged canines at front of lower jaw; opercle uniformly dark brownish; blade-like patch on cheek, the patch orange dorsally and reddish ventrally, fading entirely in preservative; dorsal fins light grayish with 2 rows of spots; a whitish longitudinal band just above lateral axis of body; dorsal surface of body with 8 irregular blackish saddles and lower half with 7 reddish bars and black dots on upper half of each bar; lower half of anal fin reddish; caudal fin grayish with upper and lower portion darker and vertical rows of orange dots on yellowish bands. The new species is most similar to Parapercis somaliensis and Parapercis kentingensis morphologically and genetically, but differs in coloration, serrations on the opercle, and body proportions. The establishment of the new species is also supported by DNA barcoding analysis.
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Hapsari, Windya Tri, Indri Wahyuni, and Rozalina Loebis. "Comprehensive Management of Congenital Cataract in Dizygotic Twin Babies." Vision Science and Eye Health Journal 1, no. 1 (November 28, 2021): 17–21. http://dx.doi.org/10.20473/vsehj.v1i1.2021.17-21.

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Introduction: One of the leading causes of infant blindness is cataract. The prevalence of congenital cataract has been estimated in the range between 1 and 15 per 10.000 children globally. Congenital cataract in twin babies is a rare case. This case will report the outcome of comprehensive management of congenital cataract in dizygotic twin babies. Case presentation: Eight months old dizygotic twin babies came to our clinic with the primary complaint of whitish appearance in the pupil of both eyes since birth. They were born aterm with cesarean delivery. The birth weight was 2.700 g and 3.100 g respectively. They were the fourth and fifth children in the family. There was no family history of congenital cataract. The visual acuity of both eyes was positive response to light stimuli. The cataract was bilateral and dense on both babies. Fundus reflex and TORCH examinations were negative. Ultrasonography (USG) of the retina was normal on both babies. Conclusions: Isolated congenital cataract in twin babies is an unusual condition that should be treated comprehensively. Congenital cataract may cause deprivation amblyopia, refractive amblyopia, and permanent vision impairment. Early diagnosis and quick treatment, such as surgical timing and visual rehabilitation, are critical to perform successful management. Comprehensive care is required to monitor the visual result of cataract surgery.
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Manoja, K. G. D., B. S. M. S. Siriwardena, P. R. Jayasooriya, D. J. L. Siriwardane, and W. M. Tilakaratne. "A Rare Clinical Presentation of Intraoral Darier's Disease." Case Reports in Pathology 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/181728.

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Darier's disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules primarily affecting seborrheic areas on the head, neck, thorax, and less frequently the oral mucosa. When oral manifestations are present, the palatal and alveolar mucosae are primarily affected. They usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions present as suprabasal clefts in the epithelium with acantholytic and dyskeratotic cells represented by “corps ronds and grains.” This paper reports a case of an adult male patient who presented with painful whitish lesions on buccal mucosa with crusty lips as the only clinical sign of Darier's disease. As this patient did not have skin lesions or family history, an intraoral biopsy confirmed the diagnosis of Darier's disease by a multidisciplinary team.
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Rinné, Susanne, Aytug K. Kiper, Constanze Schmidt, Beatriz Ortiz-Bonnin, Simone Zwiener, Guiscard Seebohm, and Niels Decher. "Stress-Kinase Regulation of TASK-1 and TASK-3." Cellular Physiology and Biochemistry 44, no. 3 (2017): 1024–37. http://dx.doi.org/10.1159/000485402.

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Background/Aims: TASK channels belong to the two-pore-domain potassium (K2P) channel family. TASK-1 is discussed to contribute to chronic atrial fibrillation (AFib) and has been together with uncoupling protein 1 found as a marker protein of brown adipose tissue (BAT) fat. In addition, TASK-1 was linked in a genome-wide association study to an increased body mass index. A recent study showed that TASK-1 inhibition is causing obesity in mice by a BAT whitening and that these effects are linked to the mineralocorticoid receptor pathway, albeit the mechanism remained elusive. Therefore, we aimed to probe whether K2P channels are regulated by serum- and glucocorticoid-inducible kinases (SGKs) which are known to modify many cellular functions by modulating ion channels. Methods: To this end we used functional co-expression studies and chemiluminescence-assays in Xenopus oocytes, together with fluorescence imaging and quantitative PCR experiments. Results: SGKs and proteinkinase B (PKB) induced a strong, dose- and time-dependent current reduction of TASK-1 and TASK-3. SGK co-expression reduced the surface expression of TASK-1/3, leading to a predominant localization of the channels into late endosomes. The down regulation of TASK-3 channels was abrogated by the dynamin inhibitor dynasore, confirming a role of SGKs in TASK-1/3 channel endocytosis. Conclusion: Stress-mediated changes in SGK expression pattern or activation is likely to alter TASK-1/3 expression at the surface membrane. The observed TASK-1 regulation might contribute to the pathogenesis of chronic AFib and provide a mechanistic link between increased mineralocorticoid levels and TASK-1 reduction, both linked to BAT whitening.
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Sanskruti Pawar, Shubhangi Manikpuriya, and Gajanan Sanap. "The Phytochemical and Pharmacological Screening of Withania Coagulans." World Journal of Biology Pharmacy and Health Sciences 16, no. 3 (December 30, 2023): 109–17. http://dx.doi.org/10.30574/wjbphs.2023.16.3.0501.

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In ancient system of the drug, colorful shops shows to cure colorful health disordes and conditions. Withania coagulans Dunal, Is generally known as ‘ Indian bubbish maker ’ Or ‘ Vegetable Rennet ’ because The part of withaniai.E fruits and Leaves are used as a coagulant. Withania coagulans(Withania coagulans) dunal belongs To Family solanaceae.Withania coagulans dunal Is a argentine- whitish In colour, It's small under shrub It Is distributed In east of The mediterranean region. It Isone Of The most important medicinal factory and It's veritably useful In ayurveda. In ayurvedic system Of drug,Withania coagulans Is fxtensively Used In diabetic Cases, antimicrobial, antitumour and also shows other colorful exertion. Coagulin H Insulated FromWithania coagulans displayed effect On The vulnerable response. The Dried Flowers were uprooted consecutively by methanol and water. Withania coagulans Show remedial effect Of The Part of whole factory Withania coagulans dunal Is A Rigid, argentine- whitish Small Shrub, about 30- 150 Cm Altitudinous. The leaves are about2.5-7.5 Cm long and1.5 Cm broad. The Seeds Are Dark Brown, Observance Shaped, rough with sharp Fruity smell. dunal Flower may contain nioactive element to Treat colorful conditions. Withania coagulans is pharmacological Important remedial Factory, generally Known As Rishyagandha. It's used In treatment of colorful conditions like Indigestion, diabetes mellitus, liver diseases, sanctification Of blood and controls blood Pressure. In addition, It's reported To control tube glucose situations and precluding renal complications. A standard protocol was Followed For The birth Of Withania coagulans. The fruits of Withania coagulans 0.28 G/ 100 Ml) Were Soaked In distilled water overnight followed by a mechanical dissipation using A sterile cotton wood and filtration through rubbish cloth.
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Al-Samman, Deena, and Mohammed Attar Bashi. "IATROSACEA FOLLOWING ABUSE OF TOPICAL STEROIDS AS A FACE-WHITENING CREAM IN MOSUL CITY." International Research Journal of Pharmacy 12, no. 2 (February 27, 2021): 5–10. http://dx.doi.org/10.7897/2230-8407.1202119.

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Objectives: To highlight the knowledge, frequency, types, and the clinical aspects of overusing TCs on the face as well as the motivation for such practice, with the aim of rising the public awareness in Mosul City. Methods: This prospective observational study included 180 patients aged 13-53 years, with steroid dermatitis resembling rosacea "Iatrosacea" with history of using TCs on face > 1 month, were evaluated at Al-Qudis Health Center for Family Medicine. Patients contradicted using TCs, or with classical rosacea were excluded. Results: The majority were females (90%). Duration was 2 months to 7 years. The motives were fairness (55%) and melasma (19%). The commonly abused drug was Betamethasone Valerate (35%). The reported side effects were facial erythema (84%), telangiectasia (79%), rebound phenomenon (66%), rosacea (56%), and acne (42%). The exacerbation on stopping TCs (63%) and skin lightening (37%) were the main reasons behind continued use; 59% were unaware about side effects of TCs; 42% obtained the products from cosmetic shop/Beautician and 27% from nurse clinic. In spite of observable side effects, 74% of abusers didn't feel guilty for applying them for protracted periods. Conclusion: Inappropriate use of TCs for cosmetic purposes is still commonly encountered in our environment, with believe TCs will correct any facial imperfection. As fair skin is correlated with beauty and social privilege, both genders of different ages, social, and educational status are indulged in this practice that exposed them to medical and social problems. It is a multiphase issue necessitates collaboration of different sectors to raise public awareness and control their easy availability to overcome this dilemma.
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Quadros, Rosileia Marinho de, Sandra Márcia Tietz Marques, Márcia Sangaletti LAVINA, and Jary André CARNEIRO JUNIOR. "FIRST REPORT OF Amblyomma brasiliense (Acari: Ixodidae) AMONG Myocastor coypus (MOLINA, 1782) IN THE PLATEAU REGION OF SANTA CATARINA, BRAZIL." Science And Animal Health 7, no. 1 (December 11, 2019): 34. http://dx.doi.org/10.15210/sah.v7i1.14109.

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This short communication reports ectoparasitism on a Myocastor coypus specimen found lifeless, killed by motor vehicles in the municipality of Lages, Santa Catarina, Brazil, near the SC-438 highway. Necropsy examination revealed the presence of ticks of the Ixodidae family on the ventral region of the animal’s body. Fourteen female specimens were collected and identified as Amblyomma brasiliense, with the following phenotypic characteristics: ornate scutum with whitish spots, strong spines on coxa I, spines on the internal border shorter than on the external border, half of the article length, and spines on the internal boarder on coxae II to IV were short and not very evident. The use of wild animals killed by motor vehicles on highways has proven to be relevant to the study of parasitic fauna. Although the occurrence of A. brasiliense among rodents has been previously reported, this is the first report in the literature of that species among M. coypus.
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Lee, Man-Gang, Su-Yu Kuo, Shih-Yu Yen, Hsia-Fen Hsu, Chung-Hang Leung, Dik-Lung Ma, Zhi-Hong Wen, and Hui-Min David Wang. "Evaluation ofCinnamomum osmophloeumKanehira Extracts on Tyrosinase Suppressor, Wound Repair Promoter, and Antioxidant." Scientific World Journal 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/303415.

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Cinnamomum osmophloeumKanehira belongs to the Lauraceae family of Taiwan’s endemic plants. In this study,C. osmophloeumKanehira extract has shown inhibition of tyrosinase activity on B16-F10 cellular system first. Whether extracts inhibited mushroom tyrosinase activity was tested, and a considerable inhibition of mushroom tyrosinase activity byin vitroassays was presented. Animal experiments ofC. osmophloeumKanehira were carried out by observing animal wound repair, and the extracts had greater wound healing power than the vehicle control group (petroleum jelly with 8% DMSO, w/v). In addition, the antioxidant capacity ofC. osmophloeumKanehira extractsin vitrowas evaluated. We measuredC. osmophloeumKanehira extract’s free radical scavenging capability, metal chelating, and reduction power, such as biochemical activity analysis. The results showed that a high concentration ofC. osmophloeumKanehira extract had a significant scavenging capability of free radical, a minor effect of chelating ability, and moderate reducing power. Further exploration of the possible physiological mechanisms and the ingredient components of skincare product for skin-whitening, wound repair, or antioxidative agents are to be done.
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sri, Ennesta A., and Jessica Herlianez Saiful. "A Rare Case of Pachydermodactyly in 25 years Old Male." International Journal of ChemTech Research 12, no. 6 (2019): 41–45. http://dx.doi.org/10.20902/ijctr.2019.120606.

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Pachydermodactyly is a rare digital fibromatosis that can be misdiagnosed with inflammatory rheumatic diseases. So far in the literature only about 150 cases of PDD have been reported. A prompt clinical diagnosis of the disease would prevent inappropriate treatment and unnecessary expensive diagnostic procedures such as biopsy or magnetic resonance imaging. Gold standard therapy for pachydermodactyly is not established yet.A rare case of a 25 years-old male patient with pachydermodactyly is reported. He complained swelling and thhickening around joints in both hands since 7 months ago. He denied having any pain or morning stiffness of the joints and was also free other symptomatic symptomps. Family history was not significant. Dermatological state showed skin colouredhyperkeratotic patches. Laboratory showed no abnormalities. Radiology results shows no bone and joint abnormalities. Dermoscopy examination on lesion shows whitish scaling and cobblestone appearance. Diagnosis of pachydermodactyly is based on anamnesis, physical examination, laboratory findings, and plain radiograph. Early and correct diagnosis is important to prevent unnececessary, expensive, and invasive diagnostic procedure
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43

Leasa, Elias Zadrach. "Aspek Legal Spirit Undang-Undang Nomor 23 Tahun 2004 Tentang Penghapusan Kekerasan Dalam Rumah Tangga." SASI 24, no. 2 (February 28, 2019): 168. http://dx.doi.org/10.47268/sasi.v24i2.131.

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Families are places where everyone in the family feels safe and comfortable from acts o violence, but in reality violence also accurs whitin the family. The enactment of Law No. 23 of 2004 on the abolition of domestic violence (hereinafter referred to as the Law of Domestic Violence) aims to prevent all forms of domestic violence, protect domestic violence victims, prosecute domestic violence perpetrators, and maintain wholeness harmonious and prosperous households. In handling it is sometimes resolved peacefully. This raises the question of whether the Law on Elimination of Domestic Violence has guaranteed the settlement of Domestic Violence according to its objectives? All forms of violence against women and children constitute a violation of human rights, so it is necessary to be protected by their dignity and dignity and guaranteed their right to life in accordance with their nature and nature without discrimination. The Criminal Act contained in Article 5 of the Act states that prohibited violence is physical violence, psychological violence, sexual violence, or neglect of the household. Many cases of domestic violence are reported but not a few are repealed by the victim for various reasons, such as still loving the perpetrator, and the perpetrator is the breadwinner in the household. The resolution of cases of domestic violence is also up to the court's decision, but this certainly brings the consequences of the objective of the Law on Elimination of Domestic Violence. Despite all forms of prevention of domestic violence, protecting the victim, prosecuting the perpetrator is reached but if the case is passed on to the court decision whether the goal of maintaining a harmonious and prosperous household unity can be achieved. The resolution of domestic violence requires the wisdom of the Law Enforcers (Police, Prosecutors, Judges).
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44

Assis, Mariana Santos de. "Quem (não) tem medo da literatura negra? O amor negro no combate ao genocídio do branqueamento." Cadernos de Literatura Comparada, no. 43 (2020): 233–53. http://dx.doi.org/10.21747/21832242/litcomp43a14.

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Historically, the idea has been constructed that the literary canon is a selection based solely on the quality of the text. Such a perspective, in addition to ignoring the undeniable power relations involved in the process, also ends up hampering the creative possibilities of many artists. In this work we will discuss some aspects of these conflicts, mainly associated with the importance of the struggle for the valorization of black litera-ture, not only as a fundamental artistic manifestation, but also as an instrument to fight the genocide of the black population, undertaken now through the defense of the miscegenation myth redemptive, the basis of the policy of whitening the Brazilian population since the end of slavery, now for the idea of a homogene-ous nationalism common to all. We understand that the best way to combat this process of extermination is to value love and the black family and only literature is capable of giving a new meaning to the centuries of brutalization and animalization of black bodies and affections.
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45

Taddeo, Vito, Francesco Epifano, Francesca Preziuso, Serena Fiorito, Nicolas Caron, Arnaud Rives, Philippe de Medina, Marc Poirot, Sandrine Silvente-Poirot, and Salvatore Genovese. "HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris." Molecules 24, no. 3 (January 30, 2019): 501. http://dx.doi.org/10.3390/molecules24030501.

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Umbelliprenin has recently been shown to have great potential as a skin whitening agent. Wishing to investigate the same effect in plant species known to biosynthesize this coumarin, three plants belonging to the Apiaceae family, namely Anethum graveolens L. (dill), Pimpinella anisum L. (anise), and Ferulago campestris (Besser) Grecescu (field ferula) were screened by HPLC analysis for their respective content of umbelliprenin in extracts obtained with different solvent mixtures and by maceration and ultrasound-assisted processes. EtOH was shown to be the best solvent, providing umbelliprenin yields ranging from 1.7% to 14.4% (with respect to the total amount of extract obtained). Extracts with the highest content of this farnesyloxycoumarin were then assayed as modulators of melanogenesis in cultured murine Melan A cells employing the same umbelliprenin obtained by chemical synthesis as the reference. A parallelism between the content of the coumarin and the recorded depigmenting effect (60% for the EtOH extract of F. campestris as the best value) was revealed for all plants extracts when applied at a dose of 100 μg/mL. Our results demonstrate that the same potential of umbelliprenin can be ascribed also to umbelliprenin-enriched plant extracts which reinforces enforce the widespread use of phyto-preparations for cosmetic purposes (e.g., A. graveolens).
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46

Santos, Leilani R. "Occupational Risk Factors of Work Stress and Family Life of on Site Workers amidst COVID 19 Pandemic: Basis for Psychological Counseling and Intervention Program." EAS Journal of Psychology and Behavioural Sciences 5, no. 05 (September 6, 2023): 111–34. http://dx.doi.org/10.36349/easjpbs.2023.v05i05.001.

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This study is intended is to identify the occupational risk factors of work stress and family life of onsite workers amidst Covid -9 Pandemic. Work stress is linked between the employee and the employer since the employee's performance is impacted by his or her stress level, which in turn impacts the company's performance. The majority of respondents were between the ages of 18 and 25, and the majority of them were female. There is not a significant relationship between the respondents' degree of occupational stress and their profile. Regardless of the potential for enormous growth, on-site workers continue to suffer from a high level of whittling down caused by factors such as high levels of stress and a lack of opportunities for advancement. The examination of the study's findings allows the researcher to provide a few critical recommendations that the onsite workers in the Philippines should evaluate and adopt to lessen workplace stressors. Performance awards are linked to the appropriate amount of supervision and training. Both of these factors are required for positive job behavior and the smooth operation of an organization. Despite the fact that there were more variables that could be considered as indicators of onsite workers' workplace stressor based on external and internal factors, the present study was only able to work on three of them because the literature supported these factors more extensively.
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47

SIADÉN, LUIS E. CHIRA, KEVIN C. WAKEMAN, STEPHEN C. WEBB, KAZUNORI HASEGAWA, and HIROSHI KAJIHARA. "Morphological and molecular diversity of rissoellids (Mollusca, Gastropoda, Heterobranchia) from the Northwest Pacific island of Hokkaido, Japan." Zootaxa 4551, no. 4 (February 3, 2019): 415. http://dx.doi.org/10.11646/zootaxa.4551.4.2.

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This study deals with four species of marine microgastropods of the family Rissoellidae. Rissoella elatior (Golikov, Gulbin & Sirenko, 1987), R. golikovi (Gulbin, 1979), R. japonica n. sp., and Rissoella sp. 1 were collected in different locations around the island of Hokkaido, Japan. Light and scanning electron microscopy (SEM) were used to study the general morphology of the shell and radula, and a region of the mitochondrial cytochrome c oxidase subunit I (COI) gene was amplified for 26 specimens. Rissoella elatior is morphologically characterized by a highly asymmetrical radula with a deep notch encircled by 10–13 minute secondary cusps on the left dorsal margin of the central tooth. Rissoella golikovi is characterized by a skeneiform shell and possession of three teeth per row on the radula. Rissoella japonica n. sp. shows five teeth per row on the radula; central tooth higher than wide; lateral and marginal teeth narrow with an outer lateral projection at the base; all teeth presenting numerous small cusps on the cutting edge. Rissoella sp. 1 is distinguished from R. japonica n. sp. in having i) very short oral lobes, ii) a mantle with a large, black patch and whitish blotches inside, and iii) different color patterns associated with the visceral mass. Although Rissoella sp. 1 probably represents an undescribed species, additional specimens are needed to complete its description. This study represents a first molecular approach to the family Rissoellidae. Studies of traditional morphological characters indicated four species, the addition of COI data raised the count to eight potential species, suggesting the occurrence of cryptic species among rissoellids.
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48

Hota, Sourabh Ranjan, Sonali Sahoo, Manojita Dash, Avishek Pahari, Bijayendranath Mohanty, and Niranjana Sahoo. "Molecular detection of Murshidia linstowi in a free-ranging dead elephant calf." Journal of Threatened Taxa 12, no. 3 (February 26, 2020): 15359–63. http://dx.doi.org/10.11609/jott.4961.12.3.15359-15363.

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Gastrointestinal helminths are ubiquitous in both domestic and wild animals. Infections are often sub-clinical except in circumstances of destabilization of host-parasite equilibrium by innate or environmental factors. The present case deals with microscopic and molecular diagnosis of Murshidia linstowi recovered from an elephant. A post-mortem examination of a free-ranging juvenile male elephant calf that had died of electrocution in Athagarh Wildlife Division revealed the presence of slender, whitish nematodes in the stomach. No gross lesions were noticed either in the site of predilection or any other internal organs. The average length of the parasites was 3.8cm. These parasites were collected for further gross as well as microscopic examination following routine parasitological techniques. Temporary mounts prepared after cleaning the nematodes in lactophenol were observed under a microscope. Morphological features such as a well-developed mouth collar, large and globular buccal capsule with fine tubercles, cone shaped oesophageal funnel, short bursa having indistinctly divided lobes and closely apposed ventral rays and stout spicules with club shaped tips bent dorsally corroborated with that of M.linstowi (male). Amplification of the rDNA from the internal transcribed spacer (ITS) region using universal nematode primers NC2 and NC5 revealed a product size of 870bp. The PCR product was subjected to sequencing followed by NCBI-BLAST which revealed 98% homology with M. linstowi. A phylogenetic study showed a maximum similarity with M.linstowi recovered from elephants in Kenya. This particular nematode species belonging to the family Strongylidae and sub-family Cyathostominae appears to be the first documented report in India.
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49

Shaw, Richard. "A Tale of Two Stories: Unsettling a Settler Family’s History in Aotearoa New Zealand." Genealogy 5, no. 1 (March 23, 2021): 26. http://dx.doi.org/10.3390/genealogy5010026.

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On the morning of the 5 November 1881, my great-grandfather stood alongside 1588 other military men, waiting to commence the invasion of Parihaka pā, home to the great pacifist leaders Te Whiti o Rongomai and Tohu Kākahi and their people. Having contributed to the military campaign against the pā, he returned some years later as part of the agricultural campaign to complete the alienation of Taranaki iwi from their land in Aotearoa New Zealand. None of this detail appears in any of the stories I was raised with. I grew up Pākehā (i.e., a descendant of people who came to Aotearoa from Europe as part of the process of colonisation) and so my stories tend to conform to orthodox settler narratives of ‘success, inevitability, and rights of belonging’. This article is an attempt to right that wrong. In it, I draw on insights from the critical family history literature to explain the nature, purposes and effects of the (non)narration of my great-grandfather’s participation in the military invasion of Parihaka in late 1881. On the basis of a more historically comprehensive and contextualised account of the acquisition of three family farms, I also explore how the control of land taken from others underpinned the creation of new settler subjectivities and created various forms of privilege that have flowed down through the generations. Family histories shape the ways in which we make sense of and locate ourselves in the places we live, and those of us whose roots reach back to the destructive practices of colonisation have a particular responsibility to ensure that such narratives do not conform to comfortable type. This article is an attempt to unsettle my settler family narrative.
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50

Chung, You Chul, Jung No Lee, Bong Seok Kim, and Chang-Gu Hyun. "Anti-Melanogenic Effects of Paederia foetida L. Extract via MAPK Signaling-Mediated MITF Downregulation." Cosmetics 8, no. 1 (March 15, 2021): 22. http://dx.doi.org/10.3390/cosmetics8010022.

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In this study, in order to explore the anti-melanogenic effect of PFE (Paederia foetida L. extract) and suggest its availability, B16F10 cells, which are murine melanoma cells, were stimulated with alpha-Melanocyte-stimulating hormone (α-MSH) to conduct an in vitro experiment. Treatment with PFE in B16F10 cells with activated melanogenesis due to stimulants showed that PFE significantly inhibits melanin content as well as intracellular tyrosinase activity within a range that does not cause cytotoxicity. In addition, Western blot assay demonstrated that PFE strongly inhibited the protein expression of not only tyrosinase-related protein (TRP)-1, -2, and tyrosinase, but also microphthalmia-associated transcription factor (MITF). Moreover, mechanism studies have shown that PFE processing inhibited the activation of melanin production by regulating the phosphorylation of each mitogen-activated protein kinase (MAPK) family in the MAPK signaling pathway. To test the biocompatibility of PFE on human skin, a primary skin irritation test was performed. The results revealed that PFE did not have any side effects on human skin. These findings suggest that PFE holds great potential as a skin whitening agent and in the prevention of hyperpigmentation disorders.
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