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Journal articles on the topic 'WebMD'

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Published: 4 June 2021
Last updated: 1 February 2022

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1

Carr, Alan F. "WebMD." Health Care on the Internet 5, no. 4 (December 2001): 75–78. http://dx.doi.org/10.1300/j138v05n04_08.

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Evans, Nicola. "WebMD Allergy app." Nursing Standard 29, no. 2 (September 16, 2014): 31. http://dx.doi.org/10.7748/ns.29.2.31.s39.

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Guidotti, T. L. "WebMD Scientific American Medicine." JAMA: The Journal of the American Medical Association 287, no. 17 (May 1, 2002): 2292–93. http://dx.doi.org/10.1001/jama.287.17.2292.

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Rivas, Ryan, Shouq A. Sadah, Yuhang Guo, and Vagelis Hristidis. "Classification of Health-Related Social Media Posts: Evaluation of Post Content–Classifier Models and Analysis of User Demographics." JMIR Public Health and Surveillance 6, no. 2 (April 1, 2020): e14952. http://dx.doi.org/10.2196/14952.

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Background The increasing volume of health-related social media activity, where users connect, collaborate, and engage, has increased the significance of analyzing how people use health-related social media. Objective The aim of this study was to classify the content (eg, posts that share experiences and seek support) of users who write health-related social media posts and study the effect of user demographics on post content. Methods We analyzed two different types of health-related social media: (1) health-related online forums—WebMD and DailyStrength—and (2) general online social networks—Twitter and Google+. We identified several categories of post content and built classifiers to automatically detect these categories. These classifiers were used to study the distribution of categories for various demographic groups. Results We achieved an accuracy of at least 84% and a balanced accuracy of at least 0.81 for half of the post content categories in our experiments. In addition, 70.04% (4741/6769) of posts by male WebMD users asked for advice, and male users’ WebMD posts were more likely to ask for medical advice than female users’ posts. The majority of posts on DailyStrength shared experiences, regardless of the gender, age group, or location of their authors. Furthermore, health-related posts on Twitter and Google+ were used to share experiences less frequently than posts on WebMD and DailyStrength. Conclusions We studied and analyzed the content of health-related social media posts. Our results can guide health advocates and researchers to better target patient populations based on the application type. Given a research question or an outreach goal, our results can be used to choose the best online forums to answer the question or disseminate a message.
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Krauskopf, Patricia Biller. "CDC Contraception and WebMD Pregnancy Mobile Apps." Journal for Nurse Practitioners 14, no. 10 (November 2018): e221-e222. http://dx.doi.org/10.1016/j.nurpra.2018.08.010.

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Au, Anson. "Why Physician Guidance Matters: A Night of Neuralgia, Meningitis, and WebMD." Annals of Family Medicine 17, no. 5 (September 2019): 462–64. http://dx.doi.org/10.1370/afm.2414.

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Swallow, Jennylee S., Jacob R. Joseph, Kylene Willsey, Andrea A. Almeida, Matthew T. Lorincz, Paul Park, Nicholas J. Szerlip, and Steven P. Broglio. "Online postconcussion return-to-play instructions." Journal of Neurosurgery: Pediatrics 21, no. 1 (January 2018): 44–48. http://dx.doi.org/10.3171/2017.7.peds17180.

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OBJECTIVEThe authors of recent concussion guidelines have sought to form a consensus on injury management, but it is unclear if they have been effective in conveying this information to the public. Many parents and athletes obtain medical recommendations via the Internet. This review is aimed at evaluating consistency between online resources and published guideline statements in postconcussion return-to-play (RTP) decisions.METHODSFive websites were selected through a Google search for RTP after concussion, including a federal government institution (Centers for Disease Control and Prevention) website, a national high school association (National Federation of State High School Associations) website, a popular nationally recognized medical website for patients (WebMD), a popular parent-driven website for parents of children who participate in sports (MomsTeam), and the website of a private concussion clinic (Sports Concussion Institute), along with a university hospital website (University of Michigan Medicine). Eight specific items from the Zurich Sport Concussion Consensus Statement 2012 were used as the gold standard for RTP recommendations. Three independent reviewers graded each website for each of the 8 recommendations (A = states guideline recommendations appropriately; B = mentions guideline recommendation; C = does not mention guideline recommendation; F = makes inappropriate recommendation).RESULTSA grade of A was assigned for 45.8% of the recommendations, B for 25.0%, C for 25.0%, and F for 4.2%. All the websites were assigned an A grade for the recommendation of no RTP on the day of injury. Only 1 website (WebMD) mentioned medication usage in conjunction with the Zurich statement, and only 2 websites (Sports Concussion Institute and University of Michigan Medicine) mentioned appropriate management of persistent symptoms. None of these websites commented correctly on all 8 guideline recommendations.CONCLUSIONSOnline resources are inconsistent in relaying guideline recommendations for RTP and provide a potential source of confusion in the management of concussion for athletes and their parents, which can result in inappropriate RTP decisions.
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Swallow, Jennylee S., Jacob R. Joseph, Kylene Willsey, Paul Park, Nicholas J. Szerlip, and Steven P. Broglio. "349 Online Resources Provide Inconsistent Return To Play Instructions Following Concussion." Neurosurgery 64, CN_suppl_1 (August 24, 2017): 279. http://dx.doi.org/10.1093/neuros/nyx417.349.

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Abstract INTRODUCTION While recent guidelines have hoped to form consensus regarding management of concussion, it is unclear if they have been effective in conveying this information to the public. Many parents and athletes obtain medical recommendations via the internet. This study aims to evaluate consistency between online resources and guideline statements in post-concussion return to play (RTP) decisions. METHODS Five websites were selected through a Google search for return to play after concussion. These websites represented a federal government institution (Centers for Disease Control, CDC); a national high school association website (National Federation of State High School Associations, NFHS); a popular nationally-recognized medical website for patients (WebMD); a University hospital (University of Michigan, UM); a popular parent-driven website for sports parents (MomsTeam, MT); as well as a website for a private concussion clinic (Sports Concussion Institute, SCI). The Zurich Sport Concussion Consensus Statement was used as the gold standard for RTP recommendations, and eight specific items identified. Three independent reviewers graded each website for each of the eight recommendations (A = states guideline recommendations appropriately; B = mentions guideline recommendation; C = does not mention guideline recommendation; F = inappropriate recommendation made). RESULTS >A grade of A was assigned for 45.8% of recommendations, B for 25.0%, C for 25.0%, and F for 4.2%. All websites were assigned grade A for recommendation of no return to play on the day of injury. Only 1 website (WebMD) commented on medication usage in conjunction with the Zurich Statement, and only 2 websites (SCI, UM) commented on management of persistent symptoms. No website correctly commented on all eight guideline recommendations. CONCLUSION Online resources are inconsistent in relaying guideline recommendations for RTP. This is a potential source of confusion in management of concussion for athletes and their parents which may result in inappropriate RTP.
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Gilbert, Stephen, Alicia Mehl, Adel Baluch, Caoimhe Cawley, Jean Challiner, Hamish Fraser, Elizabeth Millen, et al. "How accurate are digital symptom assessment apps for suggesting conditions and urgency advice? A clinical vignettes comparison to GPs." BMJ Open 10, no. 12 (December 2020): e040269. http://dx.doi.org/10.1136/bmjopen-2020-040269.

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ObjectivesTo compare breadth of condition coverage, accuracy of suggested conditions and appropriateness of urgency advice of eight popular symptom assessment apps.DesignVignettes study.Setting200 primary care vignettes.Intervention/comparatorFor eight apps and seven general practitioners (GPs): breadth of coverage and condition-suggestion and urgency advice accuracy measured against the vignettes’ gold-standard.Primary outcome measures(1) Proportion of conditions ‘covered’ by an app, that is, not excluded because the user was too young/old or pregnant, or not modelled; (2) proportion of vignettes with the correct primary diagnosis among the top 3 conditions suggested; (3) proportion of ‘safe’ urgency advice (ie, at gold standard level, more conservative, or no more than one level less conservative).ResultsCondition-suggestion coverage was highly variable, with some apps not offering a suggestion for many users: in alphabetical order, Ada: 99.0%; Babylon: 51.5%; Buoy: 88.5%; K Health: 74.5%; Mediktor: 80.5%; Symptomate: 61.5%; Your.MD: 64.5%; WebMD: 93.0%. Top-3 suggestion accuracy was GPs (average): 82.1%±5.2%; Ada: 70.5%; Babylon: 32.0%; Buoy: 43.0%; K Health: 36.0%; Mediktor: 36.0%; Symptomate: 27.5%; WebMD: 35.5%; Your.MD: 23.5%. Some apps excluded certain user demographics or conditions and their performance was generally greater with the exclusion of corresponding vignettes. For safe urgency advice, tested GPs had an average of 97.0%±2.5%. For the vignettes with advice provided, only three apps had safety performance within 1 SD of the GPs—Ada: 97.0%; Babylon: 95.1%; Symptomate: 97.8%. One app had a safety performance within 2 SDs of GPs—Your.MD: 92.6%. Three apps had a safety performance outside 2 SDs of GPs—Buoy: 80.0% (p<0.001); K Health: 81.3% (p<0.001); Mediktor: 87.3% (p=1.3×10-3).ConclusionsThe utility of digital symptom assessment apps relies on coverage, accuracy and safety. While no digital tool outperformed GPs, some came close, and the nature of iterative improvements to software offers scalable improvements to care.
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Farmer, S. E. J., M. Bernardotto, and V. Singh. "How good is Internet self-diagnosis of ENT symptoms using Boots WebMD symptom checker?" Clinical Otolaryngology 36, no. 5 (October 2011): 517–18. http://dx.doi.org/10.1111/j.1749-4486.2011.02375.x.

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Huh, Jina, Rebecca Marmor, and Xiaoqian Jiang. "Lessons Learned for Online Health Community Moderator Roles: A Mixed-Methods Study of Moderators Resigning From WebMD Communities." Journal of Medical Internet Research 18, no. 9 (September 8, 2016): e247. http://dx.doi.org/10.2196/jmir.6331.

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McGrady, Tyler, David Mannino, Elisha Malanga, Byron Thomashow, John Walsh, Robert Sandhaus, and James Stoller. "Characteristics of Chronic Obstructive Pulmonary Disease (COPD) Patients Reporting Alpha-1 Antitrypsin Deficiency in the WebMD Lung Health Check Database." Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 2, no. 2 (2014): 141–51. http://dx.doi.org/10.15326/jcopdf.2.2.2014.0160.

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Naderi, Hamid, Sina Madani, Behzad Kiani, and Kobra Etminani. "Similarity of medical concepts in question and answering of health communities." Health Informatics Journal 26, no. 2 (October 22, 2019): 1443–54. http://dx.doi.org/10.1177/1460458219881333.

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The ability to automatically categorize submitted questions based on topics and suggest similar question and answer to the users reduces the number of redundant questions. Our objective was to compare intra-topic and inter-topic similarity between question and answers by using concept-based similarity computing analysis. We gathered existing question and answers from several popular online health communities. Then, Unified Medical Language System concepts related to selected questions and experts in different topics were extracted and weighted by term frequency -inverse document frequency values. Finally, the similarity between weighted vectors of Unified Medical Language System concepts was computed. Our result showed a considerable gap between intra-topic and inter-topic similarities in such a way that the average of intra-topic similarity (0.095, 0.192, and 0.110, respectively) was higher than the average of inter-topic similarity (0.012, 0.025, and 0.018, respectively) for questions of the top 3 popular online communities including NetWellness, WebMD, and Yahoo Answers. Similarity scores between the content of questions answered by experts in the same and different topics were calculated as 0.51 and 0.11, respectively. Concept-based similarity computing methods can be used in developing intelligent question and answering retrieval systems that contain auto recommendation functionality for similar questions and experts.
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Maloney, Erin K., Thomas A. D'Agostino, Alexandra Heerdt, Maura Dickler, Yuelin Li, Jamie S. Ostroff, and Carma L. Bylund. "Sources and types of online information that breast cancer patients read and discuss with their doctors." Palliative and Supportive Care 13, no. 2 (November 4, 2013): 107–14. http://dx.doi.org/10.1017/s1478951513000862.

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AbstractObjectives:Most research examining the impact of patients seeking online health information treats internet information homogenously, rather than recognizing that there are multiple types and sources of available information. The present research was conducted to differentiate among sources and types of internet information that patients search for, intend to discuss with their doctors, and recall discussing with their doctors, and to determine how accurate and hopeful patients rate this information.Methods:We surveyed 70 breast cancer patients recruited from the waiting rooms of breast medical oncology and surgery clinics. The main variables in the study were as follows: (1) the sources and types of online information patients have read, intended to discuss, and actually discussed with their doctors, and (2) how accurately and hopefully they rated this information to be.Results:Patients read information most frequently from the websites of cancer organizations, and most often about side effects. Patients planned to discuss fewer types of information with their doctors than they had read about. They most often intended to discuss information from cancer organization websites or WebMD, and the material was most often about alternative therapies, side effects, and proven or traditional treatments. Some 76.8% of total participants rated the information they had read as very or somewhat accurate, and 61% rated the information they had read as very or somewhat hopeful.Significance of Results:Internet information varies widely by source and type. Differentiating among sources and types of information is essential to explore the ways in which online health information impacts patients' experiences.
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Rao, Allison J., Christopher J. Dy, Charles A. Goldfarb, Mark S. Cohen, and Robert W. Wysocki. "Patient Preferences and Utilization of Online Resources for Patients Treated in Hand Surgery Practices." HAND 14, no. 2 (January 5, 2018): 277–83. http://dx.doi.org/10.1177/1558944717744340.

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Background: The Internet is a widely used resource by patients however, objective data on details such as frequency of usage and specific sites visited is lacking. We surveyed patients from hand surgery practices to describe patient preferences and utilization patterns for online resources. Methods: From October 2015 to June 2016, we enrolled patients presenting to 4 orthopedic hand surgeons at 2 academic institutions. Patients completed a survey, with questions related to their preference for learning about their diagnosis and Internet utilization both before and after the visit. Results: A total of 226 patients were enrolled in the study. Forty-five percent of the patients had done online research prior to the office visit, and 81% preferred to learn about their diagnosis through verbal communication, as opposed to only 8% who listed Web site information. Fifty percent indicated that there was a greater than 50% chance or they would definitely seek additional information on the Internet after the office visit. When asked to choose from a list of Web sites to visit, the most popular Web site was WebMD. Specialty society Web sites (American Society for Surgery of the Hand and American Academy of Orthopaedic Surgeons) were less popular. Conclusions: This survey-based study found that a majority of patients utilize the Internet both before and after the office visit; however, they often utilize unregulated sites for information. This information can help physicians guide patients to high-quality Web sites for information on their clinical diagnosis and treatment.
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Promislow, Steven, John R. Walker, Mohammad Taheri, and Charles N. Bernstein. "How Well Does the Internet Answer Patients’ Questions about Inflammatory Bowel Disease?" Canadian Journal of Gastroenterology 24, no. 11 (2010): 671–77. http://dx.doi.org/10.1155/2010/957264.

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BACKGROUND: The Internet is an increasingly important source of health information.OBJECTIVE: To assess how well common websites answered patients’ questions regarding inflammatory bowel disease (IBD).METHODS: Thirty websites were identified and evaluated. Based on a previous survey of patient information needs, a comprehensive question list was developed in the three following areas: medical information (seven items), medical treatment (six items) and self-management (eight items). The websites were evaluated for the amount of information they provided to answer each question using two standard measures of information quality – the DISCERN and the Ensuring Quality Information for Patients scales.RESULTS: Four particularly strong websites, scoring highest (on a scale from 1 to 5) in terms of IBD information, were the Crohn’s and Colitis Foundation of America (mean information score 4.3), About.com (4.2), HealthCentral (3.8) and WebMD (3.8). These websites also scored well on the DISCERN and the Ensuring Quality Information for Patients quality scales. Most websites provided at least adequate information on common symptoms, complications, treatments and what is known (or not known) about the causes of IBD. However, many web-sites did not provide adequate information about prognosis, possible side effects of treatment and risks of developing cancer. Information regarding self-management was covered to a very limited extent.CONCLUSION: Websites could be strengthened by providing more of the information patients deem to be important, and by more clearly identifying sources of information and the date the information was updated. Most websites would benefit from more attention given to reducing the reading level and improving the organization of material.
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Hughes, Shannon E., and Alicia Matheson. "Subjectively Experienced Benefits and Harms of Antipsychotics According to Users’ Firsthand Accounts on the Internet." Ethical Human Psychology and Psychiatry 18, no. 3 (2016): 196–217. http://dx.doi.org/10.1891/1559-4343.18.3.196.

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This study used an analytic framework emphasizing psychotropic drugs’ subjectively experienced psychoactive properties to reframe the helpfulness and burden of antipsychotics’ effects and impacts on users’ lives. Methods: User-reported effects of aripiprazole, lurasidone, and quetiapine within 819 user reviews on two popular websites (WebMD, Ask a Patient) were examined within the drug-centered model of drug action, cited in the literature as an alternative to the conventional disease-centered model. Independent coders used QDA Miner Version 4.1.22 to code 16 physical, mental, and emotional effects, layered with codes indicating the desirability and burden of effects from users’ perspectives. Results: Most (70%) users were female, 57.5% reported taking the reviewed antipsychotic for less than 6 months, most commonly (69.1%) for a mood disorder. Antipsychotics’ benefits included improved mood stability (14.4%) and depression (13.6%); worsened anxiety/agitation was the most frequent harm (15.3%). One quarter of undesirable effects were extremely burdensome. Aripiprazole and lurasidone demonstrated activating effects, with lurasidone users reporting the highest rates of akathisia (19.5%) and worsened anxiety (19.1%). Quetiapine’s sedating effects were often helpful (28.1%) but also produced excessive sleepiness (33.3%) and poor concentration/memory (13.9%). Users appear to subjectively experience antipsychotics’ overall activating or sedating effects as a mixture of interconnected desirable and undesirable changes occurring along a continuum of burden. Conclusions and Implications for Practice: Subjective experiences of users should be central to assessing the benefits and harms of antipsychotic drugs. Reconceptualizing the role of medications in recovery is likely needed in light of mixed and variable firsthand treatment experiences.
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Talwar, PharmD, Sonia R., Amarita S. Randhawa, PharmD, Erica H. Dankiewicz, PharmD, Nancy T. Crudele, PharmD, and J. David Haddox, DDS, MD. "Caveat emptor: Erroneous safety information about opioids in online drug-information compendia." Journal of Opioid Management 12, no. 4 (July 1, 2016): 281. http://dx.doi.org/10.5055/jom.2016.0343.

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Background: Healthcare professionals and consumers refer to online drug-information compendia (eg, Epocrates and WebMD) to learn about prescription medications, including opioid analgesics. With the significant risks associated with opioids, including abuse, misuse, and addiction, any of which can result in life-threatening overdose, it is important for those seeking information from online compendia to have access to current, accurate, and complete drug information to help support clinical treatment decisions. Although compendia are informative, readily available, and user friendly, studies have shown that they may contain errors.Objective: To review and identify misinformation in drug summaries of online drug-information compendia for selected opioid analgesic products and submit content corrections to the respective editors.Methods: Between 2011 and 2013, drug summaries for Purdue's prescription opioid analgesic products from seven leading online drug-information compendia were systematically reviewed, and the requests for corrections were retrospectively categorized and classified. At least 2 months following requests, the same compendia were then reexamined to assess the degree of error resolution.Results: A total of 859 errors were identified, with the greatest percentage in Safety and Patient Education categories. Across the seven compendia, the complete or partial resolution of errors was 34 percent; therefore, nearly two thirds of the identified errors remain.Conclusion: The results of this analysis, consistent with past studies, demonstrate that online drug-information compendia may contain inaccurate information. Healthcare professionals and consumers must be informed of potential misinformation so they may consider using multiple resources to obtain accurate and current drug information, thereby helping to ensure safer use of prescription medications, such as opioids.
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Shetty, Kunal Ramanand, Rita Yu Wang, Anisha Shetty, Jessica Levi, and Nicole Leigh Aaronson. "Quality of Patient Education Sections on Otitis Media Across Different Website Platforms." Annals of Otology, Rhinology & Laryngology 129, no. 6 (January 24, 2020): 591–98. http://dx.doi.org/10.1177/0003489420902183.

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Objective: To determine the quality, content, and readability of patient education materials pertaining to otitis media across several popular online platforms focused on otolaryngology and pediatric primary care education. Methods: Online patient materials related to otitis media and directed toward parents were collected from the American Association for Family Practice (AAFP), ENT-Health section of the American Academy of Otolaryngology—Head and Neck Surgery, Healthychildren.org from the American Academy of Pediatrics, KidsHealth from Nemours, WebMD, and Wikipedia. Materials were analyzed for quality, content, and readability. The DISCERN instrument was used to score quality. A unique content score was generated based on the information provided on each website and on the medical and surgical management of otitis media. Readability scores were calculated using the Flesch-Kincaid Grade Level, Flesch Reading Ease Score, Gunning-Fog Index, Simple Measure of Gobbledygook, Coleman-Liau Index, and Automated Readability Index. Results: Overall, content was well-balanced. Information from AAFP and Healthychildren.org was focused more on medical management than other sources. The average DISCERN scores showed all sources to be of good quality with minimal shortcomings. The AAFP and KidsHealth websites had some readability scores around the 8th-grade reading level, the National Institute of Health’s upper limit recommended for public health information; however, most websites were above this recommended reading level. Conclusion: Patient education materials related to otitis media on academic and certain popular internet sites are good sources to obtain high-quality information on the topic. Patient educational background, prior knowledge and understanding of otitis media, and physician-patient partnership goals should be taken into account when referring patients to online materials.
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Marcath, Lauren A., Jingyue Xi, Emily K. Hoylman, Kelley M. Kidwell, Shawna L. Kraft, and Daniel L. Hertz. "Comparison of Nine Tools for Screening Drug-Drug Interactions of Oral Oncolytics." Journal of Oncology Practice 14, no. 6 (June 2018): e368-e374. http://dx.doi.org/10.1200/jop.18.00086.

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Purpose: Patients with cancer are an especially vulnerable population to potential drug-drug interactions (DDIs). This makes it important to adequately screen them for DDIs. The objective of this study was to compare the abilities of nine DDI screening tools to detect clinically relevant interactions with oral oncolytics. Methods: Subscription-based tools (ie, PEPID, Micromedex, Lexicomp, Facts & Comparisons) and free tools (ie, Epocrates Free, Medscape, Drugs.com, RxList, WebMD) were compared for their abilities to detect clinically relevant DDIs for 145 drug pairs including an oral oncology agent. Clinical relevance was determined by a pharmacist using Stockley’s Drug Interactions. Descriptive statistics were calculated for each tool, including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), and then compared grouped by free or subscription-based tools for the secondary analysis and analyzed via generalized estimating equations. Results: For individual metrics, PPV had overall higher values (0.88 to 0.97) relative to the low values included for sensitivity (0.65 to 0.96), specificity (0.53 to 0.93) and NPV (0.38 to 0.83). The top-performing subscription and free tools, Lexicomp and Drugs.com, had no statistically significant differences in performance. Overall, subscription tools had a significantly higher sensitivity (0.85 ± 0.017 v 0.78 ± 0.017; P = .0082) and NPV (0.57 ± 0.039 v 0.48 ± 0.032; P = .031) than free tools. No differences were observed between the specificity and PPV. Conclusion: Due to the low performance of some tools for sensitivity, specificity, and NPV, individual performance should be examined and prioritized on the basis of the intended use when selecting a DDI tool. If a strong-performing subscription-based tool is unavailable, a strong-performing free option, like Drugs.com, is available.
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Kim, Catherine, Gary Chisholm, Abby Bevolo, Beverly Shelton, Leslie Kian, Carol M. Lewis, Elizabeth A. Garcia, Randal S. Weber, and Michael Frumovitz. "Comparison of Internal Patient Satisfaction Scores at a Cancer Center With Star Ratings on Online Physician-Rating Websites." JCO Oncology Practice 17, no. 8 (August 2021): e1181-e1188. http://dx.doi.org/10.1200/op.20.00564.

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PURPOSE: Patients have been increasingly using physician-rating websites (PRWs); however, few studies have analyzed the validity of star ratings on PRWs. We aimed to compare PRW patient satisfaction scores with internally generated patient satisfaction scores (internal scores) of physicians at a large quaternary cancer center. METHODS: We collected internal scores and PRW scores for physicians at MD Anderson Cancer Center. Internal scores were based on patient responses to the Clinician and Group Consumer Assessment of Healthcare Providers and Systems patient experience (CG-CAHPS) survey. Only physicians with an internal score on the basis of ≥ 30 patient reviews were included. The median numbers of reviews and median scores were compared between internal data and four PRWs (Google, HealthGrades, Vitals, and WebMD). Both internally and on PRWs, possible scores ranged from 1 (least satisfied) to 5 (most satisfied). RESULTS: Of 640 physicians with an internal score, 510 (79.7%) met the inclusion criteria. For these 510 physicians, the median (IQR) number of internal reviews was 49.5 (30-93) and the median (IQR) internal score was 4.89 (4.81-4.93); the median number of reviews on PRWs ranged from 2 to 7, and the median score on PRWs ranged from 4.40 to 5.00. No physician had an internal score < 4, but the proportions with score < 4 on PRWs ranged from 16% to 30%. CONCLUSION: Internal patient satisfaction scores were higher and calculated from more reviews than PRW patient satisfaction scores and correlated weakly with PRW scores. Given that patients rely on PRWs when evaluating potential physicians, we recommend publishing internal scores online to give patients more complete information regarding physician performance.
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Shakeel, Faisal, Fang Fang, Kelley M. Kidwell, Lauren A. Marcath, and Daniel L. Hertz. "Comparison of eight screening tools to detect interactions between herbal supplements and oncology agents." Journal of Oncology Pharmacy Practice 26, no. 8 (February 19, 2020): 1843–49. http://dx.doi.org/10.1177/1078155220905009.

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Introduction Patients with cancer are increasingly using herbal supplements, unaware that supplements can interact with oncology treatment. Herb–drug interaction management is critical to ensure optimal treatment outcomes. Several screening tools exist to detect drug–drug interactions, but their performance to detect herb–drug interactions is not known. This study compared the performance of eight drug–drug interaction screening tools to detect herb–drug interaction with anti-cancer agents. Methods The herb–drug interaction detection performance of four subscription (Micromedex, Lexicomp, PEPID, Facts & Comparisons) and free (Drugs.com, Medscape, WebMD, RxList) drug–drug interaction tools was assessed. Clinical relevance of each herb–drug interaction was determined using Natural Medicine and each drug–drug interaction tool. Descriptive statistics were used to calculate sensitivity, specificity, positive predictive value, and negative predictive value. Linear regression was used to compare performance between subscription and free tools. Results All tools had poor sensitivity (<0.20) for detecting herb–drug interaction. Lexicomp had the highest positive predictive value (0.98) and best overall performance score (0.54), while Medscape was the best performing free tool (0.52). The worst subscription tools were as good as or better than the best free tools, and as a group subscription tools outperformed free tools on all metrics. Using an average subscription tool would detect one additional herb–drug interaction for every 10 herb–drug interactions screened by a free tool. Conclusion Lexicomp is the best available tool for screening herb–drug interaction, and Medscape is the best free alternative; however, the sensitivity and performance for detecting herb–drug interaction was far lower than for drug–drug interactions, and overall quite poor. Further research is needed to improve herb–drug interaction screening performance.
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Nowrouzi, Behdin, Basem Gohar, Behnam Nowrouzi-Kia, Martyna Garbaczewska, and Keith Brewster. "An Examination of Scope, Completeness, Credibility, and Readability of Health, Medical, and Nutritional Information on the Internet: A Comparative Study of Wikipedia, WebMD, and the Mayo Clinic Websites." Canadian Journal of Diabetes 39 (April 2015): S71. http://dx.doi.org/10.1016/j.jcjd.2015.01.267.

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Inklebarger J, James Inklebarger J., Mr Giles Gyer, Nikiforos Galanis, Mr Jimmy Michael, and Dr Ghulam Adel. "Cinchona Bark For The Treatment Of Covid-19 Pnemonia: A Modern Review Of The Potential Anti-Viral Therapuetic Applications Of An Old Treatment." International Journal of Medical Science and Clinical invention 7, no. 05 (May 1, 2020): 4795–801. http://dx.doi.org/10.18535/ijmsci/v7i05.02.

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PURPOSE: The Coronavirus 2019 (COVID-19) pandemic is an international public health emergency. Vaccines, and acute infection drugs are currently unknown, and when available, expense and distribution issues may impede distribution in undeserved areas. The aim of this systematic review was to summarize the evidence regarding cinchona bark (CB) for its potential anti-viral properties against COVID-19 STUDY DESIGN: A current literature and historical text review was conducted, limited to articles having full text or abstracts available in English, using Google Scholar, Pubmed-NCBI, ScienceDirect, and WebMD, and online book publications, with key search words, including synthetic CB analogues: chloroquine-hydroxychloroquine (CQ/HCQ) derivatives. RESULTS: Several related in-vitro studies, editorials, and expert consensus papers on quinine analogue anti-viral treatment papers and historical treatises have been published. A March 2020 CQ drug trial ongoing in China, has just reported breakthrough efficacy evidence for COVID-19 pneumonia. However, there are severe CQ shortages and direct evidence for the anti-viral therapeutic use of CB is sparse, several centuries old, and controversial. CONCLUSION: CB was for centuries known to be a natural source of quinine from which modern synthetically manufactured analogues anti-viral purposed drugs such as CQ/HCQ are based. CB may also possess anti COVID-19 activity as its historical derivatives, but with the same potential for life-threatening adverse reactions and severe drug interaction complications akin to its analogues. Issues with herbal quality control, prescriber dose inexperience, perceived risk underestimation by self-prescribers, and a misinformed propensity for consumer fraud are other concerns. However, analogue drug risk-benefit ratios indicate CB may also have some value for acute COVID-19 (cytokine storm) infection management. The existing evidence and evolving breakthrough CQ efficacy findings in China, shadowed by CQ shortage, highlight a need for modern and timely investigation of CB as cost-effective alternative COVID-19 pneumonia monotherapy.
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Aboueid, Stephanie, Samantha Meyer, James R. Wallace, Shreya Mahajan, and Ashok Chaurasia. "Young Adults’ Perspectives on the Use of Symptom Checkers for Self-Triage and Self-Diagnosis: Qualitative Study." JMIR Public Health and Surveillance 7, no. 1 (January 6, 2021): e22637. http://dx.doi.org/10.2196/22637.

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Background Young adults often browse the internet for self-triage and diagnosis. More sophisticated digital platforms such as symptom checkers have recently become pervasive; however, little is known about their use. Objective The aim of this study was to understand young adults’ (18-34 years old) perspectives on the use of the Google search engine versus a symptom checker, as well as to identify the barriers and enablers for using a symptom checker for self-triage and self-diagnosis. Methods A qualitative descriptive case study research design was used. Semistructured interviews were conducted with 24 young adults enrolled in a university in Ontario, Canada. All participants were given a clinical vignette and were asked to use a symptom checker (WebMD Symptom Checker or Babylon Health) while thinking out loud, and were asked questions regarding their experience. Interviews were audio-recorded, transcribed, and imported into the NVivo software program. Inductive thematic analysis was conducted independently by two researchers. Results Using the Google search engine was perceived to be faster and more customizable (ie, ability to enter symptoms freely in the search engine) than a symptom checker; however, a symptom checker was perceived to be useful for a more personalized assessment. After having used a symptom checker, most of the participants believed that the platform needed improvement in the areas of accuracy, security and privacy, and medical jargon used. Given these limitations, most participants believed that symptom checkers could be more useful for self-triage than for self-diagnosis. Interestingly, more than half of the participants were not aware of symptom checkers prior to this study and most believed that this lack of awareness about the existence of symptom checkers hindered their use. Conclusions Awareness related to the existence of symptom checkers and their integration into the health care system are required to maximize benefits related to these platforms. Addressing the barriers identified in this study is likely to increase the acceptance and use of symptom checkers by young adults.
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Patell, Rushad, David Johnson Einstein, Eric James Miller, Jennifer Halleck, Laura Dodge, and Mary K. Buss. "“Where did you read that?” External sources of information and patients perceptions of prognostic goals." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e24166-e24166. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e24166.

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e24166 Background: Patients receiving palliative cancer treatment frequently misperceive likelihood of benefits/toxicity. Physicians fear that external sources of information regarding treatment enhance misperceptions and complicate decision-making. We investigated the sources of external information used, how much it affects patients' misperception and influences their treatment choices. Methods: We prospectively surveyed patients with advanced solid cancers and their oncologists regarding benefits/risks of palliative therapies including likelihood of tumor response and toxicity. Patients reported information-seeking behavior pre-treatment. We compared patients’ perceptions of benefits/risks to that of their oncologists. Results: Across four disease groups, 119 eligible patients enrolled. Their median age was 65 years (range 59–73), 55% were male, and 56% had undergone prior treatment. Treatments included chemotherapy (61%), targeted therapy (15%), and immunotherapy (24%). Over two thirds, 69% of participants stated that they wanted as much as possible information from their oncologist, and nearly all (95%) stated that they felt the amount of information provided by their clinician was “just right.” However, 60% wanted at least a moderate amount of information from external sources, and 58% reported obtaining information from sources other than their oncologist. The most common external sources of information used by participants were printed materials (35%), word of mouth (26%), the American Cancer Society (24%), and WebMD (21%). Nearly one in 3 (31%) of participants felt the information from external sources influenced their decisions more than a small amount. There was no correlation between self-education and misperception of tumor response (coefficient -0.04 p = 0.6) or of treatment toxicity (coefficient 0.05, p = 0.6) relative to their treating physicians’ estimates. Conclusions: While many patients sought information from external sources, most felt they were not substantially influenced by this information. Almost all felt their oncologists provided them with adequate information. Information-seeking behavior was not associated with greater misperception regarding the treatment goals/expectations. Thus, despite a common concern about misinformation in external information sources, oncologists should support patients who seek such sources and discuss their findings.
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Yaseen, Maria, Misbah Bano, and Masood Jawaid. "Medical students utilization of e-learning re-sources; is it an informal curriculum?" International Journal of Medicine 5, no. 1 (May 3, 2017): 132. http://dx.doi.org/10.14419/ijm.v5i1.7503.

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Background: E-learning refers to the use of Internet technologies to deliver a broad range of solutions that enhance knowledge and per-formance of learners. This mode of learning can be used by institutions to improve the efficiency and effectiveness of educational inter-ventions in the face of the social, scientific, and pedagogical challenges. Worldwide, it has gained popularity in the past few decades; however, its use is highly variable among the medical schools of Pakistan. Currently, a very few number of institutions have adopted it officially in their curriculum. Despite this, many students use different E Learning resources to enhance their learning.Objective: To find out about the online resources utilized by the medical students in addition to their traditional medical curriculum to enhance their learning.Method: In this cross-sectional study, 300 participants from Dow Medical College and Jinnah Sindh Medical Universities were included after taking informed consent. A self-administered questionnaire which consists of demographic information, years of study and online resources with their usage details by the students for different subjects of basic and clinical sciences were documented.Results: Almost all the students reported to use some form of eLearning to enhance their medical understanding. The most frequently used electronic resources were Google images (61.7%) and Wikipedia (50.3%). Mostly, the students used YouTube (25.7%) for animations; Kaplan (27%) and Dr. Najeeb (15.6%) for video lectures. However, Audio lecture by Goljan (17.7%) was the only resource for podcast learning. Among discussion forums, Facebook groups (16.3%) were most popular and among static websites, Medscape (4.3%), PubMed (2.5%), WebMD (1.3%) were the most commonly used ones.Conclusion: All of the medical students used some form of eLearning in medical education in addition to their formal curriculum. This way of learning should be further implemented in the form of formal curriculum as e-learning modules for basic and clinical sciences to make learning easier, engaging and innovative for the 21st century learners.
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Alasmari, Ashwag, and Lina Zhou. "Share to Seek: The Effects of Disease Complexity on Health Information–Seeking Behavior." Journal of Medical Internet Research 23, no. 3 (March 24, 2021): e21642. http://dx.doi.org/10.2196/21642.

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Background Web-based question and answer (Q&A) sites have emerged as an alternative source for serving individuals’ health information needs. Although a number of studies have analyzed user-generated content in web-based Q&A sites, there is insufficient understanding of the effect of disease complexity on information-seeking needs and the types of information shared, and little research has been devoted to the questions concerning multimorbidity. Objective This study aims to investigate seeking of health information in Q&A sites at different levels of disease complexity. Specifically, this study investigates the effects of disease complexity on information-seeking needs, types of information shared, and stages of disease development. Methods First, we selected a random sample of 400 questions separately from each of the Q&A sites: Yahoo Answers and WebMD Answers. The data cleaning resulted in a final set of 624 questions from the two sites. We used a mixed methods approach, including qualitative content analysis and quantitative statistical analysis. Results The one-way results of ANOVA showed significant effects of disease complexity (single vs multimorbid disease questions) on two information-seeking needs: diagnosis (F1,622=5.08; P=.02) and treatment (F1,622=4.82; P=.02). There were also significant differences between the two levels of disease complexity in two stages of disease development: the general health stage (F1,622=48.02; P<.001) and the chronic stage (F1,622=54.01; P<.001). In addition, our results showed significant effects of disease complexity across all types of shared information: demographic information (F1,622=32.24; P<.001), medical diagnosis (F1,622=11.04; P<.001), and treatment and prevention (F1,622=14.55; P<.001). Conclusions Our findings present implications for the design of web-based Q&A sites to better support health information seeking. Future studies should be conducted to validate the generality of these findings and apply them to improve the effectiveness of health information in Q&A sites.
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Yang, Xiao Ping, Wei Ping Hu, and Jing Jing Wang. "Discussion on Modeling Approach of 3-Dimensional Models Based on Web3D." Applied Mechanics and Materials 300-301 (February 2013): 261–64. http://dx.doi.org/10.4028/www.scientific.net/amm.300-301.261.

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Web3D can be understood as 3D model displaying for the Internet browser. In the regard of Web3D technology, to name a few, modeling of 3D models, texture mapping of 3D models, interactive design will pose influence on the final on-line displaying. The paper discusses feasibility of Web3D technology development from modeling methods for Web3D models.
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Childs, Timothy, and Don Brutzman. "Web3D roundUP." ACM SIGGRAPH Computer Graphics 34, no. 2 (May 2000): 35–36. http://dx.doi.org/10.1145/351440.351449.

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Vale, Felipe Campos, Ernani Tiaraju de Santa-Helena, Maria Altenfelder Santos, Wania Maria do Espirito Santo Carvalho, Paulo Rossi Menezes, Caritas Relva Basso, Mariliza Henrique Silva, Ana Maroso Alves, and Maria Ines Battistella Nemes. "Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy." Revista de Saúde Pública 52 (May 22, 2018): 62. http://dx.doi.org/10.11606/s1518-8787.2018052000337.

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OBJECTIVE: To present the development and validation of the WebAd-Q Questionnaire, a self-report instrument to monitor adherence to antiretroviral therapy in HIV/AIDS centers in Brazil. METHODS: The WebAd-Q is an electronic questionnaire that has three questions about the use of antiretrovirals in the last week. It was constructed from interviews and focus groups with 38 patients. Its validity was tested in a study with a sample of 90 adult patients on antiretroviral therapy for at least three months. We used electronic monitoring bottles, pill counting, and self-report interview to compare adherence. The WebAd-Q was answered on the sixtieth day, twice, with at least one hour of interval. The viral load of the patients was obtained from the service records. We have analyzed the agreement between the answers to the WebAd-Q, the associations, and the correlations with viral load and performance compared to other measures of adherence. RESULTS: Among the invited patients, 74 (82.2%) answered the WebAd-Q. No difficulties were reported to answer the questionnaire. The average answer time was 5 min 47 sec. The set of three questions of the WebAd-Q obtained agreement of 89.8%, with Kappa of 0.77 (95%CI 0.61–0.94). The non-adherence answers of the WebAd-Q were associated with detectable viral load. We obtained moderate viral load correlations with the non-adherence scale according to the WebAd-Q. For the three questions of the WebAd-Q, patients with non-adherence answers were also reported as less adherent according to the other measures of adherence. CONCLUSIONS: The WebAd-Q answered all the issues considered relevant in the validation of questionnaires, was well understood by patients, was associated with viral load, and obtained good agreement and good performance compared to the other measures. The feasibility analysis of its implementation still depends on a national study on its applicability.
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Findling, R., R. Goldman, J. Cucchiaro, L. Deng, and A. Loebel. "The Efficacy and Safety of Lurasidone in Adolescent Patients with Schizophrenia: Results of Functional and Quality of Life Measures from a 6-week, Double-blind, Placebo-controlled Study." European Psychiatry 41, S1 (April 2017): S94. http://dx.doi.org/10.1016/j.eurpsy.2017.01.292.

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IntroductionLurasidone, an atypical antipsychotic, demonstrated efficacy and safety in adults with schizophrenia.Objective/AimsTo evaluate the efficacy and safety of lurasidone in adolescent patients with schizophrenia.MethodsAdolescents (13–17 years old) with schizophrenia were randomly assigned to six weeks of double-blind treatment with lurasidone 37 mg/day, 74 mg/day or placebo. An ANCOVA using an LOCF approach was performed to assess change from baseline on secondary study endpoints: Pediatric Quality of Life Enjoyment and Satisfaction Questionnaire (PQ-LES-Q) and Children's Global Assessment Scale (CGAS).ResultsPatients were randomized to lurasidone 37 mg/d (n = 108), 74 mg/day (n = 106), or placebo (n = 112). Placebo-adjusted LS mean improvement at week 6 on the PQ-LES-Q was 5.3 (P = 0.001) and 5.8 (P < 0.001) for the 37 mg/day and 74 mg/day groups, respectively; and, on the CGAS was 4.6 (P = 0.002) and 4.9 (P < 0.001) for the 37 mg/day and 74 mg/d groups, respectively. The most common adverse events occurring at ≥ 5% in either lurasidone group and at least twice the rate of placebo were: nausea, somnolence, akathisia, vomiting and sedation. Mean change in weight at week 6 for placebo, 37 mg/day, and 74 mg/day groups was 0.05 kg, 0.17 kg, and 0.49 kg, respectively. Lurasidone treated patients did not show clinically meaningful differences from placebo on laboratory measures of cholesterol, triglycerides, glucose, and prolactin.ConclusionsAdolescent patients with schizophrenia treated with lurasidone demonstrated significant improvement in quality of life and function. Lurasidone was generally well-tolerated and associated with minimal changes in weight and metabolic parameters. Sponsored by Sunovion Pharmaceuticals Inc. ClinicalTrials.gov identifier: NCT01911429.Disclosure of interestDr. Findling receives or has received research support, acted as a consultant and/or served on a speaker's bureau for Alcobra, American Academy of Child & Adolescent Psychiatry, American Physician Institute, American Psychiatric Press, Bracket, CogCubed, Cognition Group, Coronado Biosciences, Dana Foundation, Elsevier, Forest, Guilford Press, Ironshore, Johns Hopkins University Press, Jubilant Clinsys, KemPharm, Lundbeck, Merck, NIH, Neurim, Novartis, Otsuka, Oxford University Press, Pfizer, Physicians Postgraduate Press, Purdue, Rhodes Pharmaceuticals, Roche, Sage, Shire, Sunovion, Supernus Pharmaceuticals, Transcept Pharmaceuticals, Tris, Validus, and WebMD. Drs. Goldman, Cucchiaro, Deng, and Loebel are employees of Sunovion Pharmaceuticals Inc.
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Wang, Tao, and Wen Guang An. "The Application Research of Web3D-Based Virtual Reality Technology in Modern Distance Education." Applied Mechanics and Materials 66-68 (July 2011): 2216–19. http://dx.doi.org/10.4028/www.scientific.net/amm.66-68.2216.

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Web3D technology is an implementation of virtual reality technology in the form. This paper researches the theory and mainstream technology of the virtual reality based on Web3D technology, and explores the application of virtual reality technology in distance education, thus to further promote the development of online teaching.
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Olmedo, Héctor, Karle Olalde, and Beñat García. "MotoStudent and the Web3D." Procedia Computer Science 75 (2015): 84–94. http://dx.doi.org/10.1016/j.procs.2015.12.220.

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Riedl, Andreas. "Web3D: Entwicklung, Standards, Formate." KN - Journal of Cartography and Geographic Information 52, no. 5 (September 2002): 214–20. http://dx.doi.org/10.1007/bf03544918.

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Klima, Ivan. "Lunar landing in Web3D." ACM SIGGRAPH Computer Graphics 34, no. 2 (May 2000): 57–58. http://dx.doi.org/10.1145/351440.351583.

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Moreno, N., A. Vallecillo, and P. Fraternali. "WebML modelling in UML." IET Software 1, no. 3 (June 1, 2007): 67–80. http://dx.doi.org/10.1049/iet-sen:20060067.

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Wakita, Akira, and Fumio Matsumoto. "Information visualization with Web3D." ACM SIGGRAPH Computer Graphics 37, no. 3 (August 2003): 29–33. http://dx.doi.org/10.1145/941572.941579.

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39

Yan, Qi, Katherine J. Jensen, Rose Thomas, Alyssa R. Field, Zheng Jiang, Christian Goei, and Mark G. Davies. "Digital Footprint of Academic Vascular Surgeons in the Southern United States on Physician Rating Websites: Cross-sectional Evaluation Study." JMIR Cardio 5, no. 1 (February 24, 2021): e22975. http://dx.doi.org/10.2196/22975.

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Background The internet has become a popular platform for patients to obtain information and to review the health care providers they interact with. However, little is known about the digital footprint of vascular surgeons and their interactions with patients on social media. Objective This study aims to understand the activity of academic vascular surgeons on physician rating websites. Methods Information on attending vascular surgeons affiliated with vascular residency or with fellowships in the Southern Association for Vascular Surgery (SAVS) was collected from public sources. A listing of websites containing physician ratings was obtained via literature reviews and Google search. Open access websites with either qualitative or quantitative evaluations of vascular surgeons were included. Closed access websites were excluded. Ranking scores from each website were converted to a standard 5-point scale for comparison. Results A total of 6238 quantitative and 967 qualitative reviews were written for 287 physicians (236 males, 82.2%) across 16 websites that met the inclusion criteria out of the 62 websites screened. The surgeons affiliated with the integrated vascular residency and vascular fellowship programs in SAVS had a median of 8 (IQR 7-10) profiles across 16 websites, with only 1 surgeon having no web presence in any of the websites. The median number of quantitative ratings for each physician was 17 (IQR 6-34, range 1-137) and the median number of narrative reviews was 3 (IQR 2-6, range 1-28). Vitals, WebMD, and Healthgrades were the only 3 websites where over a quarter of the physicians were rated, and those rated had more than 5 ratings on average. The median score for the quantitative reviews was 4.4 (IQR 4.0-4.9). Most narrative reviews (758/967, 78.4%) were positive, but 20.2% (195/967) were considered negative; only 1.4% (14/967) were considered equivocal. No statistical difference was found in the number of quantitative reviews or in the overall average score in the physician ratings between physicians with social media profiles and those without social media profiles (departmental social media profile: median 23 vs 15, respectively, P=.22; personal social media profile: median 19 vs 14, respectively, P=.08). Conclusions The representation of vascular surgeons on physician rating websites is varied, with the majority of the vascular surgeons represented only in half of the physician rating websites The number of quantitative and qualitative reviews for academic vascular surgeons is low. No vascular surgeon responded to any of the reviews. The activity of vascular surgeons in this area of social media is low and reflects only a small digital footprint that patients can reach and review.
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Yang, Rui, WenJie Fan, and Jingrong Sun. "Application in the Training of Automatic Weather Station Based on Web3D Technology." International Journal of Emerging Technologies in Learning (iJET) 10, no. 4 (September 22, 2015): 34. http://dx.doi.org/10.3991/ijet.v10i4.4630.

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Automatic weather station, one of the most significant observation instruments in China, has several particular characteristics, including precise parts, complex structure and various failures. Traditional training mode always relies on physical instruments which need large amounts of investment with long update cycle. During process of training, it is subject to making damage to instruments and trainees, which leads to ineffective even terminated training. Therefore, one new training mode is badly in need. Based on Web3D technology, this paper proposes one feasible virtual training application which takes into account particular characteristics of training for automatic weather station. It also describes an overall training plan, technology architecture, major module design and detailed implementation. This application has filled the blank of virtual Web3D training for automatic weather station, and opened up one new training approach. Also, the application scope of Web3D technology has been extended, especially into virtual training of specialized instruments.
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Huang, G. Q., J. B. Zhao, and K. L. Mak. "Early Supplier Involvement in New Product Development With WeBid: A Case Study on Video Conferencing System." Journal of Computing and Information Science in Engineering 3, no. 4 (December 1, 2003): 363–65. http://dx.doi.org/10.1115/1.1618818.

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WeBid is a prototype web-based framework developed for supporting and facilitating early supplier involvement in new product development on the Internet. It provides a suite of rigorous and yet pragmatic constructs for establishing and managing the customer-supplier relationships in new product development process. This paper reports on some insights and experience gained from a real-life case study using WeBid system and approach in the tendering process of developing a Video Conferencing System (VCS).
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Zhanping Li. "WEB3D Technology Research and Application." INTERNATIONAL JOURNAL ON Advances in Information Sciences and Service Sciences 4, no. 16 (September 15, 2012): 374–80. http://dx.doi.org/10.4156/aiss.vol4.issue16.44.

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Raman, Niranjan V., and John D. Leckenby. "Factors affecting consumers’ “Webad” visits." European Journal of Marketing 32, no. 7/8 (August 1998): 737–48. http://dx.doi.org/10.1108/03090569810224128.

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Jiang, Kai, and Shan Hong Zhu. "Online Virtual Exhibition Hall Design Based on Augmented Reality." Applied Mechanics and Materials 513-517 (February 2014): 1135–38. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.1135.

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Augmented reality (AR) technology is one of the hot issues in the field of computer vision, There are many technologies for the development of online virtual display, Such as Flash, Java and Web3D technology. Web3D technology is an emerging network3D technology, in which VRML and Cult3D technologies are commonly used. This paper chooses a convenient interactive technologyCult3D, Cult3D Designer platform is given in a 3D virtual scene and product display of the implementation process, through a set of instructions to achieve user interactions with the product and the virtual museum roaming.
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Vastag, B. "WebM&M Launched." JAMA: The Journal of the American Medical Association 289, no. 7 (February 19, 2003): 833—c—833. http://dx.doi.org/10.1001/jama.289.7.833-d.

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Sitges-Serra, A. "ACS Surgery, Principles and Practice. W. W. Souba, M. P. Fink, G. J. Jurkovich, K. R. Kaiser, W. H. Pearce, J. H. Pemberton and N. J. Soper (eds). 223 × 286 mm. Pp. 1622. Illustrated. 2005. WebMD Professional Publishing: Danbury, Connecticut." British Journal of Surgery 92, no. 11 (2005): 1456. http://dx.doi.org/10.1002/bjs.5190.

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Zhang, Bing. "A Study of Construction and Function of Digitalized Platform of Museum." Advanced Materials Research 971-973 (June 2014): 1974–77. http://dx.doi.org/10.4028/www.scientific.net/amr.971-973.1974.

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Museum digitalization has broken a lot of limitations of physical museum. The rising of new media platform and the maturity and application of digital technology and mobile communication technology, especially the Web3D technology, have provided sufficient condition and broad foundation for the digitalization of museum. Based on the analysis of the status quo of the development of museum digitalization, this article briefly discusses the practical significance and value of the construction of digitalized platform of museum, and conducts in-depth exploration on the construction of digitalized platform of museum based on the Web3D technology, the three main function modules and other issues.
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Frelinger, Andrew L., Deepak L. Bhatt, Ronald D. Lee, Darcy J. Mulford, Jingtao Wu, Sai Nudurupati, Anu Nigam, et al. "Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function." Blood 120, no. 21 (November 16, 2012): 4356. http://dx.doi.org/10.1182/blood.v120.21.4356.4356.

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Abstract Abstract 4356 Background: Platelet inhibition by clopidogrel is highly variable. Patients with reduced inhibition have increased risk for major adverse cardiovascular events. The aim of this study was to determine whether known genetic, drug, dietary, compliance and lifestyle factors affecting clopidogrel absorption and metabolism fully account for the variability in clopidogrel pharmacokinetics and pharmacodynamics. Methods and Results: Healthy subjects (n=160; age 20–53; homozygous CYP2C19 extensive metabolizer genotype; no nicotine 6 weeks, prescription drugs 4 weeks, over-the-counter drugs 2 weeks, caffeine and alcohol 72 hours; confined; restricted diet) received clopidogrel 75 mg daily for 9 days. At steady-state, clopidogrel active metabolite (clopidogrelAM) pharmacokinetics varied widely between subjects (CVs 33.8% and 40.2% for clopidogrelAM AUCt and Cmax, respectively). On-treatment pharmacodynamic endpoints VASP P2Y12 platelet reactivity index (PRI), maximal platelet aggregation (MPA) to ADP, and VerifyNow P2Y12 platelet response units (PRU) also varied widely (CVs 32 – 53%). All identified factors together accounted for only 18% of inter-subject variation in pharmacokinetic parameters and 32 – 64% of inter-subject variation in PRI, MPA, and PRU. High on-treatment platelet reactivity was present in 45% of healthy, homozygous CYP2C19 extensive metabolizer subjects, free of nicotine, alcohol, and co-medications, with witnessed clopidogrel 75 mg/d treatment for 9 days. Conclusions: Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite rigorous exclusion or control of known disease, polymorphisms (CYP2C19, CYP3A5, ABCB1, PON1), non-compliance, co-medications, diet, smoking, alcohol, demographics, and pre-treatment platelet hyperreactivity. Thus, as yet unidentified factors contribute to high on-treatment platelet reactivity with its known increased risk of major adverse cardiovascular events. Disclosures: Frelinger: Takeda Pharmaceuticals: Research Funding; GLSynthesis: Research Funding. Bhatt:Medscape Cardiology: Membership on an entity's Board of Directors or advisory committees; Boston VA Research Institute: Membership on an entity's Board of Directors or advisory committees; Society of Chest Pain Centers: Membership on an entity's Board of Directors or advisory committees; American Heart Association Get With The Guidelines Science Subcommittee: Chair, Chair Other; American College of Cardiology: Editor, Clinical Trials, Cardiosource Other; Duke Clinical Research Institute: clinical trial steering committees, clinical trial steering committees Other; Slack Publications: Chief Medical Editor, Cardiology Today Intervention Other; WebMD: CME steering committees, CME steering committees Other; Amarin, AstraZeneca, Bristol-Myers Squibb, Eisai, Ethicon, Medtronic, Sanofi Aventis, The Medicines Company: Research Funding; PLx Pharma, Takeda: unfunded research Other. Lee:Takeda Global Research & Development Center, Inc: Employment. Mulford:Takeda Global Research & Development Center, Inc: Employment. Wu:Takeda Global Research & Development Center, Inc: Employment. Nudurupati:Takeda Global Research & Development Center, Inc: Employment. Michelson:Eli Lilly: Data monitoring committee and idependent external monitor of clinical trials, Research Funding; Takeda: Research Funding; Oxygen Biotherapeutics: Research Funding; Alexion: Research Funding; Omthera: Research Funding.
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Figueiredo, Mauro, José I. Rodrigues, Ivo Silvestre, and Cristina Veiga-Pires. "A Topological Framework for Interactive Queries on 3D Models in the Web." Scientific World Journal 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/920985.

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Several technologies exist to create 3D content for the web. With X3D, WebGL, and X3DOM, it is possible to visualize and interact with 3D models in a web browser. Frequently, three-dimensional objects are stored using the X3D file format for the web. However, there is no explicit topological information, which makes it difficult to design fast algorithms for applications that require adjacency and incidence data. This paper presents a new open source toolkit TopTri (Topological model for Triangle meshes) for Web3D servers that builds the topological model for triangular meshes of manifold or nonmanifold models. Web3D client applications using this toolkit make queries to the web server to get adjacent and incidence information of vertices, edges, and faces. This paper shows the application of the topological information to get minimal local points and iso-lines in a 3D mesh in a web browser. As an application, we present also the interactive identification of stalactites in a cave chamber in a 3D web browser. Several tests show that even for large triangular meshes with millions of triangles, the adjacency and incidence information is returned in real time making the presented toolkit appropriate for interactive Web3D applications.
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Yao, Wen Long. "The Development of Interactive Marine Incinerator Operational Training System Based on Web3D." Advanced Materials Research 989-994 (July 2014): 4277–80. http://dx.doi.org/10.4028/www.scientific.net/amr.989-994.4277.

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Abstract:
In this paper, the design scheme, technical route and system structure of the interactive marine incinerator operation training system based on Web3D are proposed based on the study of the marine engine room simulator project. The virtual reality technique, visual C# and IE real-time interaction technology are introduced to the marine incinerator operation training system and the development thoughts of the interactive marine incinerator operation training system based on Web3D are elaborated based on the 3D modeling optimization and real-time interaction technology. This study is a new type of marine engineering training mode, it can better meet the STCW convention in Manila amendments on incinerator equipment management requirements.
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