Academic literature on the topic 'Voie du MEP'
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Journal articles on the topic "Voie du MEP"
Sanjaya Putri, Elsa, Mohammad Fadhli, and Martinus Mujur Rose. "Voice Over Internet Protocol (VoIP) User Location Detection Application." Jurnal E-Komtek (Elektro-Komputer-Teknik) 5, no. 2 (December 30, 2021): 230–42. http://dx.doi.org/10.37339/e-komtek.v5i2.655.
Full textMaciejko, Waldemar. "The Effect of Voice over IP Transmission Degradations on MAP-EM-GMM Speaker Verification Performance." Archives of Acoustics 40, no. 3 (September 1, 2015): 407–17. http://dx.doi.org/10.1515/aoa-2015-0042.
Full textNohara, Hiroatsu. "Le capitalisme japonais en voie de reconfiguration." Mondes en développement 129, no. 1 (2005): 107. http://dx.doi.org/10.3917/med.129.0107.
Full textNesterova, T. B., N. A. Mazurok, N. V. Rubtsova, A. A. Isaenko, and S. M. Zakian. "The Vole Gene Map." ILAR Journal 39, no. 2-3 (January 1, 1998): 138–44. http://dx.doi.org/10.1093/ilar.39.2-3.138.
Full textMancini, Elena, and Roberta Martina Zagarella. "Dare voce ai pazienti nella ricerca sulle malattie rare e sui famaci orfani / Giving patients a voice in the rare diseases and orphan drugs research." Medicina e Morale 67, no. 1 (March 23, 2018): 25–40. http://dx.doi.org/10.4081/mem.2018.526.
Full textG. Eriksen, Stefka. "Medieval Literary Voices: Embodiment, Materiality and Performance, ed. Louise D’Arcens and Sif Ríkharðsdóttir. Manchester: Manchester University Press, 2022, 298 pp." Mediaevistik 36, no. 1 (January 1, 2023): 330–32. http://dx.doi.org/10.3726/med.2023.01.45.
Full textBertho, Elara. "Med Hondo, une voix anticoloniale." Cahiers d’histoire. Revue d’histoire critique, no. 142 (July 1, 2019): 139–44. http://dx.doi.org/10.4000/chrhc.11034.
Full textJany-Catrice, Florence. "Nature des services rendus aux entreprises dans les pays en voie de développement." Mondes en développement 195, no. 3 (September 22, 2021): 159–60. http://dx.doi.org/10.3917/med.195.0159.
Full textStone, W. Ross. "An editorial: Do something different: Vote!" IEEE Antennas and Propagation Magazine 56, no. 3 (June 2014): 12. http://dx.doi.org/10.1109/map.2014.6867673.
Full textSchermerhorn, Janse, Shelby Wilcox, Stephen Durning, Joseph Costello, Candace Norton, and Holly Meyer. "Graduate health professions education programs as they choose to represent themselves: A website review." MedEdPublish 13 (March 3, 2023): 13. http://dx.doi.org/10.12688/mep.19498.1.
Full textDissertations / Theses on the topic "Voie du MEP"
Simonet, Basile. "Synthèse d'outils moléculaires pour l'étude des enzymes de la voie du MEP." Electronic Thesis or Diss., Reims, 2024. http://www.theses.fr/2024REIMS023.
Full textThe MEP pathway is present in a majority of pathogen bacteria, Apicomplexa parasites and in the plastid of chlorophyllian vegetal cells to produce isoprenoids naturally. This synthetic pathway is absent from animals metabolism, therefore its seven consecutive enzymes constitute interesting targets for the development of innovative anti-infective drugs. Our project focuses on two enzymes from this pathway: the metalloenzyme IspG, an iron-sulfur clustered enzyme, which catalyzes the conversion of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate (MEcPP) into 4-hydroxy-3-methylbut-2-enyl 4-pyrophosphate (HMBPP); and the enzyme IspD, which catalyzes the conversion of 2-C-methyl-D-erythritol 4-phosphate (MEP) into 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME). In order to study the relationship between substrate MEcPP structural modifications and inhibition of the enzyme IspG, we describe therein the synthesis of trifluoromethylated analogues and mimics of the activated complex. These molecules are designed to inhibit different steps of the reaction catalyzed by IspG (carbocation formation, successive reductions, dihydroxylation). On the other hand, we describe the synthesis of MEP analogues designed as fraudulent substrates recognized by IspD. Lastly, the results of enzymatic assays testing these molecules on enzymes IspG and IspD are described
Bianchino, Gabriella ines. "La métalloenzyme IspH, une source pour la découverte de nouveaux agents antimicrobiens." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAF016.
Full textOne way to tackle the arising antimicrobial resistance is to focus on underexploited series of target enzymes. In most bacteria and some parasites, the isoprenoid precursors are synthesized via the 2C-methyl-d-erythritol 4-phosphate (MEP) pathway, which is absent in humans, and it thus represents an interesting target for the development of novel anti-infectives. IspH is an oxidoreductase containing an oxygen-sensitive [4Fe-4S]2+ cluster that catalyzes the last step of the MEP pathway converting HMBPP into IPP and DMAPP. A multidisciplinary strategy has been applied for the discovery of new classes of inhibitors against IspH from Pseudomonas aeruginosa, Mycobacterium tuberculosis and Plasmodium falciparum. A method was developed to produce the IspH orthologs as holoenzymes, followed by the development of the enzymatic assay which was used for an in vitro screening campaign of different chemical libraries. The latter led to the discovery of a novel potent inhibitor targeting the three orthologs object of this study. Moreover, a prodrug approach has been exploited for an already known E. coli IspH inhibitor ((E)-4-amino-3-methylbut-2-en-1-yl diphosphate) with the goal of reaching antibacterial, antitubercular, and antimalarial activity
Ponaire, Sarah. "Synthèse d'analogues de substrats ou d'inhibiteurs d'enzymes de la voie du 2-C-méthyl-D-érythritol 4-phosphate (MEP) pour la synthèse des isoprénoïdes." Strasbourg, 2010. https://publication-theses.unistra.fr/public/theses_doctorat/2010/PONAIRE_Sarah_2010_ED222.pdf.
Full textIsoprenoïds are components of the vast family of « natural compounds » present in all living organisms. They are biosynthetically obtained by two distinct pathways: the mevalonate pathway and the 2-C-methylerithritol 4-phosphate pathway; the latter is present in numerous pathogenous microorganisms and parasites. Growing microorganism resistance to antibiotics and antiparasitics forces us to identify new therapeutic targets to fight against pathogens. The great advantage of the 2-C-methylerithritol 4-phosphate pathway is that it is absent in humans thus being the ideal target to discover new antibiotics. To that end, we decided to synthesize six prodrugs derived from two phosphonic acids previously obtained in our research group. The latter, directly related to fosmidomycin were proven to be potent inhibitors of E. Coli’s DXR enzyme. The new prodrugs were tested on tobacco cell cultures, on BY-2 as well on Mycobacterium smegmatis. Results obtained on BY-2 show that our prodrugs are stronger inhibitors than fosmidomycin. Moreover, they still have an inhibitory effect on very low concentrations were fosmidomycin does not. In addition, organic synthesis of 2-C-methylerithritol 4-phosphate was studied. Though various protecting groups of the phosphate moiety were used and numerous protection / deprotection steps were tested, 2-C-methylerithritol 4-phosphate was never obtained. We then pursued our efforts on synthesizing dihydroyacetone phosphate, a small organic compound found in various metabolic pathways. The organic synthesis we propose surpasses all others by its simplicity and efficiency. Finally, we tried to synthesize L-glyceraldehyde 3-phosphate; this compound is the enantiomericaly pure substrate of DXS (deoxyxylulose phosphate synthase). Though many different synthetic schemes were tested, none of them yielded the desired product
Ginis, Olivia. "Identification de facteurs de transcription régulateurs de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques chez Catharanthus roseus." Thesis, Tours, 2012. http://www.theses.fr/2012TOUR4014/document.
Full textCatharanthus roseus is a tropical plant producing specifically monoterpene indole alkaloids (MIA) of high interest due to their therapeutical values. In C. roseus cells, the terpenoid branch including the methyl erythritol phosphate pathway (MEP) provides the MIA terpenoid moiety and is regarded as limited for MIA biosynthesis. This branch presents a coordinated transcriptional regulation in response to hormonal signals leading to MIA production. In this context, bioinformatic analysises and functional characterization of MEP pathway gene promoters allowed the identification of new transcription factor families involved in the MIA pathway regulation. Members of ZCT proteins, WRKY and type B RR families specifically interact with the hds promoter from the MEP pathway and regulate its activity. This work permits to gain into insight the transcriptional network controlling the MIA biosynthesis. It is possible now to consider using transcription factor that act as activators and target genes from the terpenoid branch to increase the accumulation of alkaloids of pharmaceutical interest in C. roseus by metabolic engineering approaches
Guirimand, Grégory. "Organisation cellulaire et subcellulaire de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques de Catharantus roseus." Thesis, Tours, 2011. http://www.theses.fr/2011TOUR4014/document.
Full textCatharanthus roseus is a tropical plant from the Apocynaceae family with a great therapeutic value due to its ability to synthesize monoterpene indole alkaloids (MIA) used in cancer treatment. The yields of these molecules in planta are very low due to a very high level of compartmentation of the biosynthetic pathway at both cellular and subcellular levels. While the cellular compartmentation was widely characterized, very few in situ subcellular localization data were available at the beginning of this PhD. An accurate knowledge of this compartmentation is necessary to identify intermediate metabolites transport events from one compartment to another one, in order to increase the MIA biosynthesis yield by metabolic engineering approaches. In this context we have proceed to the exhaustive study of the subcellular localization of these enzymes by in vivo GFP imaging in C. roseus cells transformed by biolistic. Potential interprotein interactions of these enzymes have also been studied by BiFC. Altogether, our results enabled us to draw an integrated model of the cellular and subcellular organization of MIA biosynthesis in situ
Chebbi, Mouadh. "Implication de facteurs de transcription de type doigt de zinc et de la famille des WRKY dans la régulation de la voie du MEP et de la biosynthèse des alcaloïdes indoliques monoterpéniques de Catharanthus roseus." Thesis, Tours, 2015. http://www.theses.fr/2015TOUR3801/document.
Full textMonoterpene indole alkaloids (MIA) are molecules with anti-cancer properties from Catharanthus roseus. Their production cost and the important need in chemiotherapy make them major targets for the research of more efficient production strategies. The aim of this work is to identify new transcription factors (TF) that regulate MIA production. This study focuses especially on the functional characterization and the involvement in the MIA biosynthesis regulation, of proteins previously isolated in the EA2106 “Plant Biocompounds and Biotechnology” laboratory: 3 proteins that belong to the WRKY family (CrWRKYs) and 3 zinc finger proteins named ZCTs. Our experiments revealed that among them, CrWRKY22, CrWRKY32, ZCT1 and ZCT2 act as transcription factors and more specifically interact with the promoter of Crhds gene. Crhds encodes an enzyme of the methyl erythritol phosphate (MEP) pathway that is considered as limiting for MIA production. Our work allowed identifying new TFs targeting the MEP pathway those regulation through TFs is mostly unknown. Using such transcription factors in metabolic engineering could be now considered increasing MIA production by the modulation of terpenoid flux in C. roseus
Sippelli, Simona. "Nouvelle Voie d'isolement du RM6P : Biosynthèse et synthèse de dérivés du M6P." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS157.
Full textThe cation-indipendent mannose-6-phosphate receptor (CI-MPR) is a trans membrane glycoprotein implicated in numerous biological processes such as the transporting of the lysosomal enzymes to the lysosomes and in the phenomenon known as angiogenesis.The analogues of M6P have proven themselves to be effectors of tumour angiogenesis.The synthesis new bidentates derivatives, functionalised with analogues derivatives of M6P, opens the way to a new method to isolate the CI-MPR.These “biological antennae” will be used to study binding affinity with the receptor CI-MPR. In prospective, a new class of Sepharose derivatives, functionalised with ours bidentates ligands, will be generated to be used in the traditional technique of purifying proteins
Garcia, Cécile. "Synthèse de nanoparticules par voie électrochimique." Toulouse 3, 2006. http://www.theses.fr/2006TOU30179.
Full textThis thesis deals with the synthesis of metallic (Ni-Co alloy) and oxide (Fe3O4), nanoparticles elaborated by an electrochemical process in ethanol medium. The study and the optimization made on the process lead to produce bimetallic nanoparticles of Ni/Co stabilized by surfactant with a rod-like morphology. A systematic experimental study shows clear relation between the synthesis parameters (current density, water percentage in ethanol, synthesis time, reagent concentration) and the morphology and structure of these Ni/Co nano-rods or wires. Magnetite (Fe3O4) nanoparticles were also obtained using a new process based on direct electro-precipitation of an oxide in a dry solvent. This very simple process allows to produce quasi-monodisperse spherical nanoparticles (2-5 nm) in an ethanol medium without any stabilizing agent. To characterize these various nanoparticles, we systematically used transmission electron microscopy and wide-angle X-ray scattering
Yang, Chenguang. "Security in Voice Authentication." Digital WPI, 2014. https://digitalcommons.wpi.edu/etd-dissertations/79.
Full textHadj-Kacem, Imed. "Allocation de ressources : optimisation des symboles pilotes et de la voie de retour." Thesis, Cergy-Pontoise, 2011. http://www.theses.fr/2011CERG0522/document.
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Books on the topic "Voie du MEP"
Finnegan, Erin. Sotto voce. [United States]: Interlude Press, 2014.
Find full textYamimaru, Enjin. Voice or noise. [Calif.]: Blu, 2007.
Find full textHarel, Jean-Pierre. Silences à voix haute. Montréal: Quinze, 1985.
Find full textHarel, Jean-Pierre. Silences à voix haute. Montréal: Les Quinze, 1985.
Find full textSmith, Curt. The voice: Mel Allen's untold story. Chicago, Ill: Triumph Books, 2006.
Find full textEdwardson, Åke. Voile de pierre: Roman. Paris: Jc Lattès, 2006.
Find full textMaya, Slater, ed. Women voice men: Gender in European culture. Exeter, England: Intellect, 1997.
Find full textFebick, Walter. Different voices: A different voice and other stories. San Francisco: GLB Publishers, 1999.
Find full textFøltved, Lis. Vore sociale rettigheder: Med oversigt over sociale takster. 5th ed. København: Idag, 1987.
Find full textVII, Université de Paris, ed. James Agee: Let us now praise famous men, ou, La voie du réel. Lille: A.N.R.T, Université de Lille III, 1989.
Find full textBook chapters on the topic "Voie du MEP"
Robert, Jacques. "La voie des MAP kinases." In Signalisation cellulaire et cancer, 45–58. Paris: Springer Paris, 2010. http://dx.doi.org/10.1007/978-2-8178-0028-8_3.
Full textMcCarthy, Barry, and Emily J. McCarthy. "The War Between Women and Men." In Finding Your Sexual Voice, 1–14. New York, NY : Routledge, 2019.: Routledge, 2018. http://dx.doi.org/10.4324/9780429446078-1.
Full textMcCarthy, Barry, and Emily J. McCarthy. "Women and Men as Intimate and Erotic Allies." In Finding Your Sexual Voice, 145–57. New York, NY : Routledge, 2019.: Routledge, 2018. http://dx.doi.org/10.4324/9780429446078-11.
Full textLaing, Sarah J. "Map-Do-Review." In The Theory and Practice of Voice in Early Childhood, 19–34. London: Routledge, 2022. http://dx.doi.org/10.4324/9780429259630-4.
Full textSmith, Rosalind. "‘In a mirrour clere’: Protestantism and Politics in Anne Lok’s Miserere mei Deus." In ‘This Double Voice’, 41–60. London: Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62888-9_3.
Full textDovchin, Sender, Alastair Pennycook, and Shaila Sultana. "Transglossia and Sports: Men Talk and Masculinity." In Popular Culture, Voice and Linguistic Diversity, 111–37. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-61955-2_5.
Full textXiao, Shuangjin. "In Search of a Varied Voice." In Two English-Language Translators of Jin Ping Mei, 103–45. London: Routledge, 2024. http://dx.doi.org/10.4324/9781003472674-3.
Full textMargrave, Christie. "Reading the Absence: The Shaping of Male Characters and Their Crises in the Void." In Women Writing Men, 56–74. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003274001-5.
Full textLarsen, Eirinn. "Earning the Vote with Honour. Suffrage, Economic Independence, and Gender in Norway, ca. 1814–1919." In Suffrage, Capital, and Welfare, 35–57. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-69864-4_2.
Full textFaulkner, Robert. "Icelandic Men, Male Voice Choirs and Masculine Identity." In Perspectives on Males and Singing, 215–31. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2660-4_14.
Full textConference papers on the topic "Voie du MEP"
Islam, Rumana, and Mohammed Tarique. "Spectrogram and Mel-Spectrogram Based Dysphonic Voice Detection Using Convolutional Neural Network." In 2024 International Conference on Electrical, Computer and Energy Technologies (ICECET), 1–5. IEEE, 2024. http://dx.doi.org/10.1109/icecet61485.2024.10698112.
Full textYadav, Shailaja, and Dinkar Yadav. "Dysarthria Voice Disorder Detection Using Mel Frequency Logarithmic Spectrogram and Deep Convolution Neural Network." In 2024 First International Conference on Electronics, Communication and Signal Processing (ICECSP), 1–6. IEEE, 2024. http://dx.doi.org/10.1109/icecsp61809.2024.10698732.
Full textEmektar, Miraç, Furkan Günaydın, and Fatih Mehmet Harmancı. "Mind Map-Based Testing Strategies in VoIP Systems: A Case Study on SIP Pbx Products." In 2024 9th International Conference on Computer Science and Engineering (UBMK), 1127–32. IEEE, 2024. https://doi.org/10.1109/ubmk63289.2024.10773600.
Full textTeja, Beeram Bhanu, Madan Lal Saini, Edupalli Greeshmanth Kumar, and Syed Abbas Khadar Ali. "Utilizing Artificial Neural Networks and Mel-Frequency Cepstral Coefficients for Gender Identification from Voice Data." In 2024 8th International Conference on Computational System and Information Technology for Sustainable Solutions (CSITSS), 1–6. IEEE, 2024. https://doi.org/10.1109/csitss64042.2024.10816760.
Full textGerhana, Yana Aditia, Muhammad Reza Abdul Fatah, Agung Wahana, Muhammad Insan Al Amin, and Ichsan Budiman. "Classification of Human Voice Types Using Convolutional Neural Network Algorithm with Extraction of Mel-Frequency Cepstral Coefficients." In 2024 12th International Conference on Cyber and IT Service Management (CITSM), 1–6. IEEE, 2024. https://doi.org/10.1109/citsm64103.2024.10775826.
Full textNorhizat, Mohd Taufiq, Nurul Azira Mohd Zorkifli, Hazlinda Hakimie, and Norashidah Md Din. "VoIP over MYREN." In 2nd Malaysia Conferenced on Photonics (MCP). IEEE, 2008. http://dx.doi.org/10.1109/nctt.2008.4814281.
Full textHosseini, Pegah T., Farshad Almasganj, and Mansour R. Darabad. "Pathological voice classifcation using local discriminant basis and genetic algorithm." In Automation (MED 2008). IEEE, 2008. http://dx.doi.org/10.1109/med.2008.4602260.
Full textFrigui, Imed, and Attahiru S. Alfa. "Three buffer-allocation schemes for a MAP/PH/1/K priority queue with vacations and an application to ATM networks." In Voice, Video, and Data Communications, edited by Seyhan Civanlar and Indra Widjaja. SPIE, 1997. http://dx.doi.org/10.1117/12.290465.
Full textElshamy, Elsayed M., Hamdy M. Kelash, Aziza I. Hussein, Hesham F. A. Hamed, M. A. Abdelghany, and M. A. Abdelghany. "Secure VoIP System Based on Biometric Voice Authentication and Nested Digital Cryptosystem using Chaotic Baker's map and Arnold's Cat Map Encryption." In 2017 International Conference on Computer and Applications (ICCA). IEEE, 2017. http://dx.doi.org/10.1109/comapp.2017.8079739.
Full textChang, H. M. "Augmented phonetic map for voice verification." In [Proceedings] ICASSP-92: 1992 IEEE International Conference on Acoustics, Speech, and Signal Processing. IEEE, 1992. http://dx.doi.org/10.1109/icassp.1992.226093.
Full textReports on the topic "Voie du MEP"
Jerkeby, Stefan. I Lacans ateljé: 11 föreläsningar om förklarandets innebörder. Karlstad University, 2024. http://dx.doi.org/10.59217/isvk1693.
Full textKang, George S., and David A. Heide. Transcoding Between Two DoD Narrowband Voice Encoding Algorithms (LPC-10 and MELP). Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/adb248890.
Full textBoyer, Marcel, Hicham El Moussaoui, and Valentin Petkantchin. Le microentrepreneuriat et l’accès à l’eau potable dans les quartiers précaires d’Abidjan (Côte d’Ivoire). CIRANO, November 2024. http://dx.doi.org/10.54932/lyeb4146.
Full textRamnath, Rishabh, Neale Kinnear, Sritika Chowdhury, and T. Hyatt. Interacting with Android Auto and Apple CarPlay when driving: The effect on driver performance. TRL, January 2020. http://dx.doi.org/10.58446/sjxj5756.
Full textZankina, Emilia. Populism and Polycrisis in Bulgaria on the Eve of the 2024 European Parliament Elections. European Center for Populism Studies (ECPS), October 2024. http://dx.doi.org/10.55271/rp0063.
Full textKarlsson, Milla, Jens Sundström, Anna Berlin, and Erik Andreasson. Möjliga tillämpningar av nya genomiska tekniker inom integrerat växtskydd. Swedish University of Agricultural Sciences, 2023. http://dx.doi.org/10.54612/a.3n00ebeumo.
Full textBiscaia, Afonso, and Susana Salgado Salgado. The 2024 European Elections and Right-wing Populism in Portugal. European Center for Populism Studies (ECPS), October 2024. http://dx.doi.org/10.55271/rp0080.
Full textBaluga, Anthony, and Bruno Carrasco. The Role of Geography in Shaping Governance Performance. Asian Development Bank, December 2020. http://dx.doi.org/10.22617/wps200378.
Full textSietins, Jennifer, Ngon Tran, Daniel Knorr Jr, Jason Cain, and Keaton Klaff. Porosity and Void Size Quantification in Carbon Materials with X-ray-Computed Tomography (XCT)and Mercury Infiltration Porosimetry(MIP). Aberdeen Proving Ground, MD: DEVCOM Army Research Laboratory, August 2022. http://dx.doi.org/10.21236/ad1177018.
Full textLazo, Jeff, and Brian Mills. Weather-Water-Climate Value Chain(s): Giving VOICE to the Characterization of the Economic Benefits of Hydro-Met Services and Products. American Meteorological Society, September 2021. http://dx.doi.org/10.1175/weather-water-climate-value-chain-voice-2021.
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