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Academic literature on the topic 'Vnd-its'

Author: Grafiati
Published: 26 July 2024

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Journal articles on the topic "Vnd-its"

1

Skeath, J. B., G. F. Panganiban, and S. B. Carroll. "The ventral nervous system defective gene controls proneural gene expression at two distinct steps during neuroblast formation in Drosophila." Development 120, no. 6 (June 1, 1994): 1517–24. http://dx.doi.org/10.1242/dev.120.6.1517.

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Within the Drosophila embryo, the formation of many neuroblasts depends on the functions of the proneural genes of the achaete-scute complex (AS-C): achaete (ac), scute (sc) and lethal of scute (l'sc), and the gene ventral nervous system defective (vnd). Here, we show that vnd controls neuroblast formation, in part, through its regulation of the proneural genes of the AS-C. vnd is absolutely required to activate ac, sc and l'sc gene expression in proneural clusters in specific domains along the medial column of the earliest arising neuroblasts. Using ac-lacZ reporter constructs, we determined that vnd controls proneural gene expression at two distinct steps during neuroblast formation through separable regulatory regions. First, vnd is required to activate proneural cluster formation within the medial column of every other neuroblast row through regulatory elements located 3′ to ac; second, through a 5′ regulatory region, vnd functions to increase or maintain proneural gene expression in the cell within the proneural cluster that normally becomes the neuroblast. By following neuroblast segregation in vnd mutant embryos, we show that the neuroectoderm forms normally and that the defects in neuroblast formation are specific to particular proneural clusters.
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2

Le, Dung C. "Assessment of the willingness of households to pay for clean water use in Cang Long district, Tra Vinh province." Journal of Agriculture and Development 02 (April 29, 2019): 12–18. http://dx.doi.org/10.52997/jad.2.02.2019.

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This study aimed to estimate the willingness of households to pay for domestic clean water use against its price in rural areas of Cang Long district, Tra Vinh province. This research also identified the possibility and factors affecting the willingness to pay for a given price of 6,500 VND or above per m3 of clean water. A contingent valuation method with multiple prices (bidding game) ranging from VND 5,000 to VND 9,000 per m3 of clean water was applied to interview 120 households in Cang Long district. Results showed that the mean willingness to pay was VND 6,200 for each m3 of clean water used. The income positively affected the willingness to pay against the price of 6,500 VND or above whereas the household size had a negative impact on this parameter. It is suggested that the service provider should consider to extent the minimum volume of water used up to 10 m3/month instead of 4 m3/month in accordance with the minimum price of 5,700 VND per m3 of water used.
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3

Pekel, Engin, and Selin Soner Kara. "Solving Capacitated Location Routing Problem by Variable Neighborhood Descent and GA-Artificial Neural Network Hybrid Method." PROMET - Traffic&Transportation 30, no. 5 (November 9, 2018): 563–78. http://dx.doi.org/10.7307/ptt.v30i5.2640.

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This paper aims to find the optimal depot locations and vehicle routings for spare parts of an automotive company considering future demands. The capacitated location-routing problem (CLRP), which has been practiced by various methods, is performed to find the optimal depot locations and routings by additionally using the artificial neural network (ANN). A novel multi-stage approach, which is performed to lower transportation cost, is carried out in CLRP. Initially, important factors for customer demand are tested with an univariate analysis and used as inputs in the prediction step. Then, genetic algorithm (GA) and ANN are hybridized and applied to provide future demands. The location of depots and the routings of the vehicles are determined by using the variable neighborhood descent (VND) algorithm. Five neighborhood structures, which are either routing or location type, are implemented in both shaking and local search steps. GA-ANN and VND are applied in the related steps successfully. Thanks to the performed VND algorithm, the company lowers its transportation cost by 2.35% for the current year, and has the opportunity to determine optimal depot locations and vehicle routings by evaluating the best and the worst cases of demand quantity for ten years ahead.
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4

Huynh, Minh Thuan, Van Nhan Truong, Duong Hai Le, Ngoc Thanh Tran, Van Chuong Bui, Quang Hieu Pham, Hong Hoa Pham, and Minh Hieu Nguyen. "Evaluating the digitalization capability and display of KPIs for two fertilizer plants of Petrovietnam." Petrovietnam Journal, no. 2 (December 25, 2023): 68–76. http://dx.doi.org/10.47800/pvsi.2023.02-08.

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The study partially funded by the Vietnam Oil and Gas Group (Petrovietnam) assesses the infrastructure, OT/IT systems, and data handling at two fertilizer plants. Although well-equipped with automation control technology, the plants lack seamless integration, connectivity, and encounter limitations in communication between systems. To address these issues, the study advocates for the integration of digital technology, emphasizing its potential for enhancing efficiency, facilitating optimal management, and guiding strategic direction. Following an assessment of infrastructure, key performance indicator (KPI) system requirements, and data management, the study proposes an initial application of digital technology to link KPI displays. The outlined scope, initial costs, investment phases, and implementation schedule indicate a total initial investment of around VND 37 - 39 billion, accompanied by annual maintenance costs ranging from VND 3.7 to 4.1 billion. Expected economic and social benefits involve improved management at both Petrovietnam and plant levels through the KPI system, with an estimated energy cost savings of 1%, equivalent to roughly VND 44.6 billion. The project aims to position the fertilizer plants and Petrovietnam as leaders in technology, contributing to sustainability and enhancing their global industry reputation.
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5

Yoo, Si-Uk. "Kinetic analysis of Drosophila Vnd protein containing homeodomain with its target sequence." BMB Reports 43, no. 6 (June 30, 2010): 407–12. http://dx.doi.org/10.5483/bmbrep.2010.43.6.407.

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6

Chen, Shifeng, Rong Chen, and Jian Gao. "A Modified Harmony Search Algorithm for Solving the Dynamic Vehicle Routing Problem with Time Windows." Scientific Programming 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/1021432.

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The Vehicle Routing Problem (VRP) is a classical combinatorial optimization problem. It is usually modelled in a static fashion; however, in practice, new requests by customers arrive after the initial workday plan is in progress. In this case, routes must be replanned dynamically. This paper investigates the Dynamic Vehicle Routing Problem with Time Windows (DVRPTW) in which customers’ requests either can be known at the beginning of working day or occur dynamically over time. We propose a hybrid heuristic algorithm that combines the harmony search (HS) algorithm and the Variable Neighbourhood Descent (VND) algorithm. It uses the HS to provide global exploration capabilities and uses the VND for its local search capability. In order to prevent premature convergence of the solution, we evaluate the population diversity by using entropy. Computational results on the Lackner benchmark problems show that the proposed algorithm is competitive with the best existing algorithms from the literature.
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7

Maghfiroh, Meilinda Fitriani Nur, and Anak Agung Ngurah Perwira Redi. "Tabu search heuristic for inventory routing problem with stochastic demand and time windows." Jurnal Sistem dan Manajemen Industri 6, no. 2 (November 23, 2022): 111–20. http://dx.doi.org/10.30656/jsmi.v6i2.4813.

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This study proposes the hybridization of tabu search (TS) and variable neighbourhood descent (VND) for solving the Inventory Routing Problems with Stochastic Demand and Time Windows (IRPSDTW). Vendor Managed Inventory (VMI) is among the most used approaches for managing supply chains comprising multiple stakeholders, and implementing VMI require addressing the Inventory Routing Problem (IRP). Considering practical constraints related to demand uncertainty and time constraint, the proposed model combines multi-item replenishment schedules with unknown demand to arrange delivery paths, where the actual demand amount is only known upon arrival at a customer location with a time limit. The proposed method starts from the initial solution that considers the time windows and uses the TS method to solve the problem. As an extension, the VND is conducted to jump the solution from its local optimal. The results show that the proposed method can solve the IRPSDTW, especially for uniformly distributed customer locations.
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8

Galibina, Natalia A., Tatiana V. Tarelkina, Olga V. Chirva, Yulia L. Moshchenskaya, Kseniya M. Nikerova, Diana S. Ivanova, Ludmila I. Semenova, Aleksandra A. Serkova, and Ludmila L. Novitskaya. "Molecular Genetic Characteristics of Different Scenarios of Xylogenesis on the Example of Two Forms of Silver Birch Differing in the Ratio of Structural Elements in the Xylem." Plants 10, no. 8 (August 2, 2021): 1593. http://dx.doi.org/10.3390/plants10081593.

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Silver birch (Betula pendula Roth) is an economically important species in Northern Europe. The current research focused on the molecular background of different xylogenesis scenarios in the birch trunks. The study objects were two forms of silver birch, silver birch trees, and Karelian birch trees; the latter form is characterized by the formation of two types of wood, non-figured (straight-grained) and figured, respectively, while it is currently not clear which factors cause this difference. We identified VND/NST/SND genes that regulate secondary cell wall biosynthesis in the birch genome and revealed differences in their expression in association with the formation of xylem with different ratios of structural elements. High expression levels of BpVND7 accompanied differentiation of the type of xylem which is characteristic of the species. At the same time, the appearance of figured wood was accompanied by the low expression levels of the VND genes and increased levels of expression of NST and SND genes. We identified BpARF5 as a crucial regulator of auxin-dependent vascular patterning and its direct target—BpHB8. A decrease in the BpARF5 level expression in differentiating xylem was a specific characteristic of both Karelian birch with figured and non-figured wood. Decreased BpARF5 level expression in non-figured trees accompanied by decreased BpHB8 and VND/NST/SND expression levels compared to figured Karelian birch trees. According to the results obtained, we suggested silver birch forms differing in wood anatomy as valuable objects in studying the regulation of xylogenesis.
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9

Huy, Huynh, Luu Thi, Nguyen Khang, and Nguyen Trinh. "Estimating the economic value of the ecotourism destination: The case of Tra Su Melaleuca Forest Natural Park in Viet Nam." Journal of the Geographical Institute Jovan Cvijic, SASA 73, no. 3 (2023): 379–86. http://dx.doi.org/10.2298/ijgi2303379h.

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In this article, the application of the Individual Travel Cost Method (ITCM) aims at providing a deeper insight into visitors? preferences and their expenses on marketed and non-marketed services when travelling to the Tra Su Melaleuca Forest Natural Park, an ecotourism destination in An Giang Province of Viet Nam. The empirical findings from the survey of 237 visitors in 2022 showed that the frequency of trips to this recreational site was 1.3 per year on average and relied strongly on the travel costs. Additionally, the estimate of tourism revenues for 2022 of this site was 82,3 billion Viet Nam Dong (VND; equivalent to 3,5 million USD). Meanwhile, its economic value calculated by the ITCM application reaches 206,2 billion VND (or 8,8 million USD). It is obvious that a greater economic value over the monetary amount of revenue also raises several ideas of managerial implications dedicated to the recreational site. It includes building a marketing team for developing recreational services and digital marketing performance, expanding tour services like transportation, lodging, local guides. Finally, enabling local people to engage in dialogues, decision-making, and interest shares is also necessary for the sustainable development of ecotourism.
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10

Wei, Ming, Guan Long Deng, Zhen Hao Xu, and Xing Sheng Gu. "Parallel Machine Tardiness Scheduling Based on Improved Discrete Differential Evolution." Advanced Materials Research 459 (January 2012): 266–70. http://dx.doi.org/10.4028/www.scientific.net/amr.459.266.

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To study the identical parallel machine scheduling problem with total tardiness objective, an improved discrete differential evolution DDE_VND is presented. The proposed algorithm hybridizes discrete differential evolution (DDE) with variable neighborhood descent (VND) to enhance its local search ability. Moreover, a constructive heuristic MDD is employed to generate an initial solution in the algorithm to accelerate the convergence of the algorithm. At last, the experimental results based on 50 benchmark instances validate the effectiveness of the DDE_VND algorithm
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