Dissertations / Theses on the topic 'Vitamins in human nutrition'
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Wilkins, Jennie P. "Relationship between maternal prenatal vitamin use and infant iron status." Morgantown, W. Va. : [West Virginia University Libraries], 2002. http://etd.wvu.edu/templates/showETD.cfm?recnum=2381.
Full textTitle from document title page. Document formatted into pages; contains vi, 43 p. Vita. Includes abstract. Includes bibliographical references (p. 34-36).
Favret, Jenny C. "An incidence study of vitamin and mineral supplementation among infants in Southwest Virginia." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/101275.
Full textM.S.
Clarke, Michael William. "Vitamin E metabolism in humans." University of Western Australia. School of Medicine and Pharmacology, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0191.
Full textSyphard, James Eric. "Sports supplement database /." Link to this database on the INTERNET, 2003. http://sportsupplementdb.project.cisat.jmu.edu/.
Full textWolberg, Charlene. "The influence of vitamin D3 supplementation on the components of the metabolic syndrome." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/80088.
Full textENGLISH ABSTRACT: The possible advantages of vitamin D supplementation on various cardiometabolic conditions have been examined over the past few years. Vitamin D supplementation has possibly shown effects on each of the individual components of the metabolic syndrome i.e.: obesity, hypertension, dyslipidaemia and glucose intolerance. The aim of this systematic review was to ascertain whether or not vitamin D supplementation has any effect on any of the components of the metabolic syndrome. We searched the (Cochrane Central Register of Controlled Trails (Central), Medline, Science direct, ISI Web of knowledge and Scopus during 2010 (repeated search in 2012). We found four randomized controlled trials that met our inclusion and exclusion criteria. Three hundred and seventy three patients were included in these four randomized controlled trails comparing vitamin D supplementation with placebo. Duration of treatment was a minimum of 4 weeks, through to a maximum of on-year. The different trials looked at various components of the metabolic syndrome as outcomes. The results were not consistent amongst the trials and the results could not be combined in a meta-analysis due to heterogeneity in study design and outcomes measured. The current systematic review highlights the shortcomings in the published data and we recommend further trials be undertaken before vitamin D supplementation can be recommended as beneficial for patients with the metabolic syndrome.
AFRIKAANSE OPSOMMING: Die moontlike voordele van vitamien D-aanvullings op verskillende kardiometaboliese toestande is oor die afgelope paar jaar ondersoek. Daar is aangetoon dat vitamien Daanvullings uitwerkings het op elk van die individuele komponente van die metaboliese sindroom naamlik vetsug, hipertensie, dislipidemie en glukose-intoleransie. Die doel van hierdie sistematiese oorsig was om vas te stel of vitamien D-aanvullings enige uitwerking het op enige van die komponente van die metaboliese sindroom of nie. Ons het gedurende 2010 soektogte uitgevoer op die Cochrane Sentrale register van gekontroleerde proewe (Central), Medline, Science Direct, ISI Web of Knowledge en Scopus (soektog is in 2012 herhaal). Ons het vier verewekansigde gekontroleerde proewe wat aan ons insluiting- en uitsluitingskriteria voldoen het, opgespoor. Driehonderd drie en sewentig pasiënte is by die vier proewe ingesluit. Al vier proewe het vitamien D-aanvullings met plasebo vergelyk. Die duur van behandeling het van 4 weke tot een jaar gestrek. Die verskillende proewe het gekyk na verskillende komponente van die metaboliese sindroom as uitkomste. Die resultate van die onderskeie proewe was nie konsekwent nie. Die huidige sistematiese oorsig belig die tekortkominge in die gepubliseerde data en ons beveel aan dat verdere proewe onderneem word om vas te stel of dit nuttig is om vitamien D aanvullings vir pasiënte met die metaboliese sindroom aan te beveel, en of dit dalk skadelik kan wees.
Nelson, Monica. "Serum 25-Hydroxyvitamin D Response to Daily Oral Supplementation with 800 IU Cholecalciferol in Premenopausal Women Living in Maine." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/NelsonM2007.pdf.
Full textSimoneau, Nathalie. "Attributes of vitamin A and calcium-rich foods consumed in K'asho Got'ine, NWT." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27412.
Full textFradera, Ursula G. "Impact of vitamin A nutrified soybean oil on the vitamin A status of a selected community in Southern Brazil." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28986.
Full textLand and Food Systems, Faculty of
Graduate
Santos, Vanessa Lorenço Peresi dos [UNESP]. "Associação entre os polimorfismos do gene BCMO1 (β-caroteno 15,15'-monooxigenase 1) e as concentrações séricas de β-caroteno e retinol em diferentes etnias brasileiras." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/132849.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
A vitamina A tem importância na nutrição humana, uma vez que a sua deficiência é considerada um sério problema de saúde pública e de morbimortalidade infantil. Carotenóides pró-vitamina A, particularmente o β-caroteno proveniente de determinados alimentos de origem vegetal, são importantes fontes de vitamina A para muitas populações. Durante o processo de bioconversão os carotenóides são clivados pela enzima citossólica β-caroteno 15,15'-monooxigenase 1 (BCMO1). Dois polimorfismos (Single Nucleotide Polymorphisms - SNPs) no gene BCMO1, R267S: rs12934922 e A379V: rs7501331, foram identificados em populações de etnias Caucasiana, Japonesa e Chinesa, podendo causar redução da atividade enzimática da BCMO1 e justificar a ampla diferença inter-individual na bioconversão do β-caroteno em vitamina A. Os objetivos deste estudo foram identificar a frequência das variantes polimórficas A379V e R267S/A379V do gene BCMO1 em três grupos populacionais brasileiros (brancos, negros e japoneses) e avaliar a relação entre os SNPs com as concentrações séricas de β-caroteno e retinol entre os três diferentes grupos étnicos. Cada grupo foi composto de 100 indivíduos voluntários, com ancestralidades Europeia, Africana e Japonesa, sendo 50% do gênero feminino e 50% do gênero masculino. Foram avaliadas as concentrações séricas de β-caroteno, retinol, zinco eritrocitário, linfócitos, proteína C-reativa, α-1-glicoproteína ácida e a ingestão alimentar de Vitamina A. Amostras de saliva e esfoliado de células da mucosa oral foram coletadas para a extração de DNA com posterior genotipagem dos SNPs A379V: rs7501331 e R267S: rs12934922 por RT-PCR. As frequências das variantes alélicas R267S e A379V com, pelo menos, um alelo T para os indivíduos com ancestralidade Europeia foram 63,0% e 44,0%, respectivamente, com ancestralidade Africana, 48,0% e 18,0%, respectivamente, e com ancestralidade Japonesa, 21,0% e 27,0%,...
Vitamin A is important in human nutrition, since deficiency is considered a serious public health and child mortality. Provitamin A carotenoids, particularly β-carotene from certain plant foods are important sources of vitamin A for many populations. During the bioconversion process carotenoids are cleaved by cytosolic enzyme β-carotene 15,15'-monooxygenase 1 (BCMO1). Two polymorphisms (Single Nucleotide Polymorphisms - SNPs) in BCMO1 gene, R267S: rs12934922 and A379V: rs7501331, were identified in ethnic populations of Caucasian, Japanese and Chinese, and it may cause reduced enzyme activity BCMO1 and justify the wide inter-individual differences in bioconversion of β-carotene into vitamin A. The aims of this study were to identify the frequency of polymorphic variants A379V and R267S/A379V of BCMO1 gene in three population groups (whites, blacks and Japanese) and evaluate the relationship between SNPs with serum β-carotene and retinol among three different ethnic groups. Each group was composed of 100 volunteers, with European, African and Japanese ancestry, and 50% were female and 50% male. Were evaluated plasmatic concentrations of β-carotene, retinol, zinc erythrocyte, lymphocytes, C-reactive protein, α-1-acid glycoprotein and dietary intake of Vitamin A. Samples of saliva and oral mucosa exfoliated cells were collected for DNA extraction with subsequent genotyping of SNPs R267S: rs12934922 and A379V: rs7501331 by RT-PCR. The frequencies of allelic variants R267S and A379V at least one T allele for individuals with European ancestry were 63.0% and 44.0%, respectively, African ancestry, 48.0% and 18.0%, respectively, and Japanese ancestry, 21.0 % and 27.0%, respectively. The results show, so unique, that the frequencies of polymorphic variants of the polymorphic variants A379V and R267S BCMO1 gene in Brazilian population groups evaluated depend on ethnicity for both SNPs. The polymorphic variants observed do not seem to ...
FAPESP: 2011/07057-2
Santos, Vanessa Lorenço Peresi dos. "Associação entre os polimorfismos do gene BCMO1 (β-caroteno 15,15'-monooxigenase 1) e as concentrações séricas de β-caroteno e retinol em diferentes etnias brasileiras /." Botucatu, 2015. http://hdl.handle.net/11449/132849.
Full textCoorientador: Daisy Maria Favero Salvadori
Banca: Marcos Ferreira Minicucci
Banca: Maria Rita Marques de Oliveira
Banca: Mário Sérgio Mantovani
Banca: Raquel Alves dos Santos
Resumo: A vitamina A tem importância na nutrição humana, uma vez que a sua deficiência é considerada um sério problema de saúde pública e de morbimortalidade infantil. Carotenóides pró-vitamina A, particularmente o β-caroteno proveniente de determinados alimentos de origem vegetal, são importantes fontes de vitamina A para muitas populações. Durante o processo de bioconversão os carotenóides são clivados pela enzima citossólica β-caroteno 15,15'-monooxigenase 1 (BCMO1). Dois polimorfismos (Single Nucleotide Polymorphisms - SNPs) no gene BCMO1, R267S: rs12934922 e A379V: rs7501331, foram identificados em populações de etnias Caucasiana, Japonesa e Chinesa, podendo causar redução da atividade enzimática da BCMO1 e justificar a ampla diferença inter-individual na bioconversão do β-caroteno em vitamina A. Os objetivos deste estudo foram identificar a frequência das variantes polimórficas A379V e R267S/A379V do gene BCMO1 em três grupos populacionais brasileiros (brancos, negros e japoneses) e avaliar a relação entre os SNPs com as concentrações séricas de β-caroteno e retinol entre os três diferentes grupos étnicos. Cada grupo foi composto de 100 indivíduos voluntários, com ancestralidades Europeia, Africana e Japonesa, sendo 50% do gênero feminino e 50% do gênero masculino. Foram avaliadas as concentrações séricas de β-caroteno, retinol, zinco eritrocitário, linfócitos, proteína C-reativa, α-1-glicoproteína ácida e a ingestão alimentar de Vitamina A. Amostras de saliva e esfoliado de células da mucosa oral foram coletadas para a extração de DNA com posterior genotipagem dos SNPs A379V: rs7501331 e R267S: rs12934922 por RT-PCR. As frequências das variantes alélicas R267S e A379V com, pelo menos, um alelo T para os indivíduos com ancestralidade Europeia foram 63,0% e 44,0%, respectivamente, com ancestralidade Africana, 48,0% e 18,0%, respectivamente, e com ancestralidade Japonesa, 21,0% e 27,0%,...
Abstract: Vitamin A is important in human nutrition, since deficiency is considered a serious public health and child mortality. Provitamin A carotenoids, particularly β-carotene from certain plant foods are important sources of vitamin A for many populations. During the bioconversion process carotenoids are cleaved by cytosolic enzyme β-carotene 15,15'-monooxygenase 1 (BCMO1). Two polymorphisms (Single Nucleotide Polymorphisms - SNPs) in BCMO1 gene, R267S: rs12934922 and A379V: rs7501331, were identified in ethnic populations of Caucasian, Japanese and Chinese, and it may cause reduced enzyme activity BCMO1 and justify the wide inter-individual differences in bioconversion of β-carotene into vitamin A. The aims of this study were to identify the frequency of polymorphic variants A379V and R267S/A379V of BCMO1 gene in three population groups (whites, blacks and Japanese) and evaluate the relationship between SNPs with serum β-carotene and retinol among three different ethnic groups. Each group was composed of 100 volunteers, with European, African and Japanese ancestry, and 50% were female and 50% male. Were evaluated plasmatic concentrations of β-carotene, retinol, zinc erythrocyte, lymphocytes, C-reactive protein, α-1-acid glycoprotein and dietary intake of Vitamin A. Samples of saliva and oral mucosa exfoliated cells were collected for DNA extraction with subsequent genotyping of SNPs R267S: rs12934922 and A379V: rs7501331 by RT-PCR. The frequencies of allelic variants R267S and A379V at least one T allele for individuals with European ancestry were 63.0% and 44.0%, respectively, African ancestry, 48.0% and 18.0%, respectively, and Japanese ancestry, 21.0 % and 27.0%, respectively. The results show, so unique, that the frequencies of polymorphic variants of the polymorphic variants A379V and R267S BCMO1 gene in Brazilian population groups evaluated depend on ethnicity for both SNPs. The polymorphic variants observed do not seem to ...
Doutor
Tshihwanambi, T. P. "Consumption patterns of vitamin a-rich foods of 10-13 year old children living in a rural area in Venda." Pretoria : [s.n.], 2008. http://upetd.up.ac.za/thesis/available/etd-06132008-154920.
Full textChaomuangbon, Sunthorn. "The Response of Elderly People to a B-6 Supplement." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc500731/.
Full textNihan, Laura. "Conjunctival Impression Cytology Assessment of Vitamin A Status of Migrant Children." DigitalCommons@USU, 1995. https://digitalcommons.usu.edu/etd/5437.
Full textHenderson, Susan Ahlstrom. "Vitamin A Status, Anthropometric Measurements, and Food Practices of Women of Childbearing Age and Their Preschool Children in Northeast Brazil." DigitalCommons@USU, 1987. https://digitalcommons.usu.edu/etd/5354.
Full textChrisley, Barbara Mc. "Separation and quantitation of the seven forms of vitamin B-6 in plasma and 4-pyridoxic acid in urine of adolescent girls by reverse phase high performance liquid chromatography." Diss., Virginia Polytechnic Institute and State University, 1988. http://hdl.handle.net/10919/53934.
Full textPh. D.
Guenther, Isabel. "The relationship between serum leptin, 25-hydroxyvitamin D₃, and body composition." Connect to this title, 2008. http://scholarworks.umass.edu/theses/196/.
Full textHeffernan, Mary Elizabeth Peterson Catherine Ann. "The effects of regular tanning bed use and increased vitamin D status on bone mineral density and serum inflammatory markers in healthy women." Diss., Columbia, Mo. : University of Missouri--Columbia, 2007. http://hdl.handle.net/10355/5024.
Full textPowell, Lisa. "Effects of various diets on vitamin B-6 and cholesterol levels in ten men aged 21-37." Virtual Press, 1990. http://liblink.bsu.edu/uhtbin/catkey/722433.
Full textDepartment of Home Economics
Exebio, Joel. "The Effect of Vitamin D Supplementation on Cardiovascular Risk Factors among Minorities with Type 2 Diabetes." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2266.
Full textMorkel, Ryan Andrew. "Vitamin B12 and folate enrichment of kefir by Propionibacterium freudenreichii and Streptococcus thermophilus strains." Thesis, Cape Peninsula University of Technology, 2016. http://hdl.handle.net/20.500.11838/2339.
Full textIn South Africa malnutrition exists due to inadequate dietary intake of micronutrients which is one of the major causes of vitamin deficiencies leading to disease. The treatment of malnutrition over the past years has been a considerable burden on the South African economy. Therefore, food fortification is one of the current strategies used to minimize malnutrition by increasing the nutritional value of staple foods. Commercial dairy products and pharmaceutical nutritional products (food supplements) in South Africa have been developed and produced for affluent consumers. Hence the need to develop an affordable fortified dairy product for the majority of South Africans prompted this study aimed at using a “naturally” fortified kefir beverage with vitamin B12 and folate to increase B-vitamins levels. Since Propionibacterium freudenreichii and Streptococcus thermophilus are known to be good producers of vitamin B12 and folate, respectively, and propionibacteria has the ability to grow symbiotically in the presence of lactic acid bacteria, the inclusion of these organisms with the kefir grains was an achievable objective. In order to conduct the analysis of vitamin B12 and folate in the samples, sample extraction and HPLC assay techniques were developed. The extraction of vitamin B12 and folate were achieved by using KCN extraction buffer and the trienzymatic method, respectively. The samples were also subjected to purification and concentration using solid phase extraction for optimum results. All standards and samples were flushed with nitrogen gas and stored for a maximum of 2 weeks at –20°C to prevent B-vitamin deterioration. The HPLC assembly for the vitamin B12 analysis included a Luna C18 column and a diode array detector (DAD) for the detection and quantification. For the folate analysis it included a Zorbax SB-C18 and Luna C18 columns in tandem and the fluorescence detector (FLD) was used for the detection and quantification of THF, 5-CH3-THF and 5-CHO-THF, while the DAD was used for PGA and pteroyltri-γ-L-glutamic acid concentration in the samples.
Martini, Fabiana Cristina Camargo. "Comparação entre a disponibilidade de ferro na presença de vitamina A e beta-caroteno em alimentos e medicamentos." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/11/11141/tde-02012003-133746/.
Full textIron and vitamin A are essential nutrients for the development and maintenance of human body. This study aims to check the availability of iron in presence of vitamin A, in carrot, bean, bovine liver and in the medicines Arovit Neutrofer and Fer-In-Sol, as well as in their combinations. Also it aimed to quantify the proximate composition, minerals, antinutritionals, heme and nonheme iron, retinol and beta-carotene in foods and their combinations with medicines. The amount of medicines added to foods was figured based on a previous analysis of the iron and beta-carotene food composition. The amount of iron sulfate (Fer1) and iron aminoquelate (N1), corresponds to the amount of iron found in the bean samples. Fer2 and N2 correspond to the iron concentration found in the bovine liver samples. Vitamin A was figured through carrot beta-carotene conversion. The combination of foods and medicines showed: (C), (C+A1), (C+N1), (C+N2), (C+Fer1), (C+Fer2), (C+F), (F), (F+A1), (F+Fer2), (F+N2), (F+Fi), (Fi), (Fi+A1), (Fi+Fer1), (Fi+N1) and (Fi+C). The results obtained were analyzed statistically through the Tukey test (5%), making use of the SAS System. The carrot samples showed higher moisture (88,12 %) and beta-carotene (6,42 mg/100g). The bean samples showed higher concentration of carbohydrates (10,68 %), dietetic fiber (7,47 %), being also determined the tannins (0,05 %) and phytic acid (2,71 mg/g). The bovine liver samples showed higher concentration of ash (2,13 %), crude fat (7,01 %), proteins (31,35 %), being also determined vitamin A (71285 UI/100g), heme iron (31,85 mcg/g) and iron available. Mineral concentrations were also measured. The vitamin A concentrations ranged from 2247 UI/100g (C+F) to 71285 UI/100g (Fi) and it was figured through the conversion of the retinol and beta-carotene concentration of the samples. The heme and nonheme iron amount were determined only in the liver sample, and ranged from 13,06 mcg/g (F+Fi) to 31,85 mcg/g (Fi) and from 2,45 mcg/g (Fi+C) to 9,48 mcg/g (Fi+Fer1) respectively. The "in vitro" iron dialyse was used to quantify the amount of iron available in the samples. In the liver samples, it was considered the nonheme iron plus 25 % of the heme iron part. The iron available concentration ranged from 0,12 mg/kg (F) to 8,10 mg/kg (Fi). There was no minerals influence on the iron availability. The antinutricional tannins and phytic acid had an inhibitor effect on the iron availability. Vitamin A and beta-carotene had a positive effect on the iron availability. The carrot and bovine liver showed better iron dialyze percentage than their respective medicines of similar concentration. Therefore, it was concluded that vitamin A had a positive effect on the iron availability and, being the bovine liver samples the ones which showed better iron available concentration and are feasible to consume according to the daily needs of iron.
Natarajan, Radhika. "Vitamin D metabolites inhibit adipocyte differentiation in ₃T₃-L₁ preadipocytes." Connect to this title, 2008. http://scholarworks.umass.edu/theses/164/.
Full textZarini, Gustavo G. "The Effect of Vitamin D3 Supplementation on Kidney Function and Cardiovascular Disease Markers among Hispanics and African Americans with Type 2 Diabetes." FIU Digital Commons, 2017. http://digitalcommons.fiu.edu/etd/3376.
Full textScherf, Kayla K. "Vitamin D Status of American Adults Age 18 Years and Older: National Health And Nutrition Examination Survey 2001-2002 and 2003-2004." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1225454830.
Full textChávez, Verónica. "Determination of seric retinol levels in relation to consumed diet and the prevalence of anemia in preschool- and school-aged children in the communities of Cuambo and La Rinconada, Imbabura province." BYU ScholarsArchive, 2003. https://scholarsarchive.byu.edu/etd/5347.
Full textGermano, Romilda Maria de Arruda. "Disponibilidade de ferro na presença do B-Caroteno e o efeito dos interferentes em combinações de alimentos." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/11/11141/tde-19082002-152718/.
Full textIn the world, iron deficiency and vitamin A deficiency reach alarming numbers, affecting population with level economic-social lower as well as people in better positions. This research aims to estimate the iron availability in the presence of b-carotene in food mixtures irons sources (spinach, bean and egg) and b-carotenes sources (carrot, pumpkin and cabbage), with low prices, that have resulted nine mixtures, denominated: M1= egg and pumpkin; M2= spinach and pumpkin; M3= spinach and cabbage; M4= egg and cabbage; M5= spinach and carrot; M6= egg and carrot; M7= bean and carrot; M8= bean and pumpkin and M9= bean and cabbage. In this food mixtures, after cooking, were studied proximate composition, levels of oxalic acid, phytic acid, tannin, minerals, in vitro dialyzability of iron and levels of b-carotene. The statistical analysis was determinate (Tukey 5%) by SAS System. The food mixtures M1, M4, M6 showed low levels of dietetic fiber, 1,32, 1,35, 1,54 g/100g and the bigger results to protein 6,80, 7,13, 6,59 g/100g and to crude fat 4,77, 4,79, 5,73 g/100g, respectively. The oxalic acid ranges to 0,14 from 0,27%, with bigger results in food mixtures with spinach; phytic acid ranges to 0,00 from 1,03 mg/g, with high levels in beans samples; the tannin ranges to 0,01 from 0,14 with high levels in spinachs samples. b-carotene showed levels ranges to 4,62 from 26,10 mg/100g. With regard to minerals, its ranges to 0,19 from 1,00 g/Kg in phosphorus; to 0,82 from 1,37 g/Kg in potassium; to 0,17 from 0,92 g/Kg in calcium; to 0,03 from 0,18 g/Kg in magnesium; to 0,19 from 0,93g/Kg in sulfur; to 0,00 from 0,65 mg/Kg in cupper; to 6,87 from 14,99 mg/Kg in iron; 0,00 a 13,08 mg/Kg in manganese and to 2,88 from 7,16 mg/Kg in zinc. In vitro dialyzability of iron ranges to 3,39 from 31,11%, and the best result was M6. Its concluded that dietetic fiber was an inhibitor in the irons absorption. And, food mixtures with egg, mainly M6 (egg and carrot), increased iron availability and that crude protein and crude fat were more significant in absorptions increase than b-carotene.
Cruz-Espaillat, Grisseel A. "A Cross-Sectional Study: Dietary Micronutrient Levels in Allied Health and Nursing Students." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/350.
Full textOrton, Sarah-Michelle. "Environmental factors in multiple sclerosis susceptibility and outcome : a focus on vitamin D." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670043.
Full textMurphy, Stephanie A. "Effects of selenium and vitamin B-6 on growth of chemically- induced transplanted tumors in BALB/c inbred mice." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/43906.
Full textMaster of Science
Kam, May-sin, and 甘美倩. "Vitamin D and influenza in school children." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45172407.
Full textChapman, Laurie A. "Interactions of nutrients on methyl mercury toxicity in neuron X spinal chord hybrid cells (NSC-34) and human oligodendrocyte X rhabdomyosarcoma cells (MO3.13)." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36888.
Full textPoirier, Johanne 1959. "The effects of selenium and vitamin E intake on diet-induced oxidative stress and hyperlipidemia /." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31526.
Full textLeonard, Franciska. "Modulation of the intestinal vitamin D receptor and calcium ATPase activity by essential fatty acid supplementation." Diss., University of Pretoria, 1999. http://hdl.handle.net/2263/24269.
Full textGoetz, Hilary Jane. "Development and application of an HPLC-MS/MS method for the characterization and quantification of a-retinyl esters and vitamin A in human plasma after consumption of a-carotene." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1408551701.
Full textHashemi, Dana. "The role vitamins in human life." Thesis, Київський національний університет технологій та дизайну, 2019. https://er.knutd.edu.ua/handle/123456789/13181.
Full textBruno, Richard S. "The role of oxidative stress and vitamin C on vitamin E utilization in humans." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1085146668.
Full textTitle from first page of PDF file. Document formatted into pages; contains xiv,148 pages; also includes graphics Includes bibliographical references (p. 121-136). Available online via OhioLINK's ETD Center
Nälsén, Cecilia. "Measurement and Evaluation of Antioxidant Status and Relation to Oxidative Stress in Humans." Doctoral thesis, Uppsala University, Clinical Nutrition Research, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6742.
Full textNumerous diseases are associated with reduced antioxidant defence and oxidative stress. The antioxidant defence includes dietary and endogenous antioxidants and involves complex interactions between them. The effects of dietary factors on antioxidant status and oxidative stress of healthy humans were investigated in the studies described in this thesis. Assays of plasma antioxidant capacity encompass interactions between various antioxidants. Although uric acid has an unclear function as an antioxidant, it is a major determinant of antioxidant capacity. We measured antioxidant capacity in the presence and absence of uric acid to provide more information on the application of measures of antioxidant capacity. Individuals with high dietary intakes of various antioxidants and antioxidant rich foods, especially when combined, had higher plasma antioxidant capacities than those with lower antioxidant intakes. However, there were no associations between dietary intake of antioxidants or antioxidant rich foods and the plasma concentration of F2-isoprostanes, which is considered a reliable biomarker for oxidative stress. Intakes of various doses of a mixture of bilberry juice and black tea, rich in flavonoids for four weeks, increased antioxidant capacity in some groups, but urine levels of F2-isoprostanes were not affected. There were substantial individual variations in responses to the drinks related to baseline antioxidant capacity. Supplementation with eicosapentaenoic acid and docosahexaenoic acid decreased the plasma levels of F2-isoprostanes, but not prostaglandin F2α formation or antioxidant capacity.
It was concluded that a high intake of foods rich in antioxidants is related to improved antioxidant status. After intake of foods rich in antioxidants, the antioxidant status may increase, but with considerable individual variation in the responses, which warrants further investigation. Lipid peroxidation in vivo is not easily affected by dietary antioxidants in healthy humans. Although n-3 fatty acids are highly unsaturated, they reduce nonenzymatic free radical-catalyzed lipid peroxidation, but not enzymatic lipid peroxidation.
Gale, Catherine Rose. "Antioxidant vitamins, cerebrovascular disease and cognitive function in elderly people." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264648.
Full textFavaro, Patricia Barbosa. "Associação entre deficiência de cobalamina e folato e presença dos polimorfismos MTR A2756C e MTRR A66G em gestantes e seus recém nascidos." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-12012018-095817/.
Full textMethionine synthase reductase (MTRR) catalyzes the reductive reaction of oxidized cobalamin to methylcobalamin. When folate is present, methionine synthase (MTR) uses methylcobalamin cofactor at homocysteine to methionine methylation process. The aim of this study was to evaluate the effects of MTR A2756G and MTRR A66G polymorphisms on total homocysteine (tHcy), methylmalonic acid (MMA), S-adenosylmethionine (SAM) concentrations and SAM/SAH ratio in Brazilian pregnant women and their newborns. Genotypes of two polymorphisms were determined by PCR-RFLP. MTR 2756AA genotype was associated with higher tHcy and MMA levels in mothers and babies, respectivelly. Lower cobalamin concentrations associated with MTRR 66AG and GG genotypes increased risk to elevated tHcy levels in pregnant women. The SAM levels were lower in neonates with MTRR 66AG e GG genotypes. The polymorphisms MTR A2756G and MTRR A66G could affect cobalamin and folate dependent reactions in pregnant women and newborns.
Santschi, Debora. "Fate of B-complex vitamins in the gastrointestinal tract of dairy cows." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81432.
Full textWu, Jason H. Y. "Vitamin E and atherosclerosis : investigation of novel biological activities and metabolism of gamma-tocopherol in humans." University of Western Australia. School of Medicine and Pharmacology, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0019.
Full textWest, Virginia Anne. "Stability of Selected B Vitamins in Thermally-Treated Pinto Beans." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5769.
Full textGIORDANO, DEBORAH. "Transglutaminase, nutrition and human health." Doctoral thesis, Università degli Studi di Foggia, 2019. http://hdl.handle.net/11369/382619.
Full textBackground: transglutaminases (TGase) are a class of enzymes widely spread in eukaryotic and prokaryotic organisms. Enzymes of this family catalyze post-translational modifications in many proteins by acyl transfer reactions, deamidation and crosslinking (polymerisation) between protein intra- or inter-chain glutamine (acyl donor) and lysine (acyl acceptor) peptide residues. Due to its facility of expression and purification, the only TGase enzyme widely used for industrial applications is the microbial TGase extracted from Streptomyces mobaraensis (MTGase). Nowadays the MTGase is commercially available and widely used in biopolymers industry, in cosmetics, in clinical applications, in wool textiles, and above all in the food processing industry. Its ability to catalyze crosslinks on many different protein substrates is increasingly used not only for sausage, ham and cheese production but, very recently, also for flour detoxification, as a possible alternative therapy to the gluten free diet. It follows that nowadays the industrial applications of MTGase have increased, covering more and more fields producing a very active scientific research about this topic aimed at attempt to meet specific industrial needs, as the implementation of more efficient system for MTGase production, the research of alternative sources of microbial TGase, and safe source of recombinant enzymes. Aims of the doctorate project: the main aim of the project is the identification of novel forms of microbial TGases that could become an alternative to that in use. A depth screening of known sequences has been performed, with the aim of obtaining a classification of microbial TGases for their similarity to known forms. To select the best candidates to be active forms under appropriate conditions, molecular modelling and molecular simulations have been performed on selected sequences. To test the enzymatic activity, experimental assays have been performed with a novel form, and another novel form has been expressed. Results: the present work proposes at first an analysis, lacking so far, of the wide microbial transglutaminase world, developing the first classification of the microbial TGase based on their sequence features and their specific predicted secondary structures. In order to classify and analyze the structural features of all the sequences annotated as having a TGase core computational techniques involving sequence analyses, comparative studies, building of phylogenetic trees, homology models and molecular dynamic simulations have been used. From this approach, a preliminary classification of these sequences was done by dividing them in five main groups. Each group has been investigated from the sequence point of view to analyze the presence of specific motifs. For three of this five groups, also the secondary structures have been investigated and, from this analysis, features specific for each group have been detected. Moreover, two novel forms of microbial TGase (mTGase) have been investigated in the detail: K. albida mTGase and the hypothetical mTGase from SaNDy (organism not disclosed for patent opportunity). Molecular dynamics simulations and active site pocket analyses have been performed for the first, in comparison with MTGase. For the second, instead, experimental technique has been used to purify the hypothetical enzyme in order to test it on food related substrates. Experimental assays on both the proteins are still ongoing, to find the best enzymatic activity conditions and the best substrates of reaction. The molecular dynamic simulations performed on K. albida mTGase have suggested some explanations to the higher specificity of this enzyme than MTGase, experimentally demonstrated by Steffen et colleague, and several indications to change the activity conditions used to test it. Moreover, the substrates screening has allowed to find novel possible substrates, on which this enzyme could be employed for the allergenicity reduction. On the other hand, the enzyme extracted from SaNDy, showing a higher similarity with MTGase, could be less selective than K. albida mTGase for specific substrates, so it could be possible its application also on the gliadin substrate, but to prove it further experiments are necessary. Note: the present PhD work has been mainly performed in the Bioinformatics Laboratory at the CNR of Avellino under Dr. Facchiano’s supervision, however all the MD simulations have been performed at the Biochemistry Department of the University of Zurich, in the computational and structural biology laboratory under the supervision of Prof. A. Caflisch and his research group (compulsory abroad training period). Experimental activity assays on gliadin substrate have been performed by the spectrometry mass CeSMA-ProBio lab at the CNR of Avellino; and the hypothetical mTGase from SaNDy was instead cloned, expressed and purified in collaboration with the Laboratory for Molecular Sensing at the CNR of Avellino.
Agustiana, Agatha. "The dose-response effects of the amount of oil in salad dressing on the bioavailability of carotenoids and fat-soluble vitamins in salad vegetables." Thesis, Iowa State University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1596916.
Full textThe objectives of the study were to define the dose-response relation of the amount of added oil and: 1) the absorption of carotenoids, phylloquinone and tocopherols in salad vegetables and 2) the absorption of retinyl palmitate formed from the ingested provitamin A carotenoids, |A- and |A-carotene. Women (n = 12) each consumed 5 salads containing equivalent amounts of carrot, cherry tomato, romaine lettuce and spinach. The salads with salad dressings containing 0, 2, 4, 8 or 32 g tocopherol-stripped soybean oil were ingested in random order separated by !Y 2 weeks. Blood samples were collected at baseline and 2, 3.5, 5, 7, and 9.5 h postprandially. Chylomicron fractions were extracted and analyzed by HPLC with coulometric array electrochemical detection. When the salads were ingested with 0 g oil, there was negligible absorption of |A- and |A-carotenes, lutein, lycopene, phylloquinone, retinyl palmitate, |A- and |?-tocopherols. For |A- and |A-carotenes, lycopene, retinyl palmitate, and |A- and |?-tocopherols, absorption was increased with each amount of oil compared with 0 g oil (P <0.05). Starting from 4 g oil, all analytes (|A-carotene, |A-carotene, lutein, trans-lycopene, vitamin A, |A-tocopherol, |?-tocopherol, and vitamin K1) showed significant increases in absorption compared with 0 g oil salad dressing. The absorption of each carotenoid and fat-soluble vitamin was highest with 32 g ingested oil (P < 0.002).
REIS, ROGERIO A. de S. "Caracterização de componentes inorgânicos em suplementos nutricionais pelo método de análise por ativação com nêutrons." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11401.
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Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
Sullivan, Allison. "Dietary Nutrient Intake and Cytokines in Children with Asthma and Allergic Disease." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1573810939821528.
Full textRoberts, Kristen M. "Dietary Bioactives and Human Prostate Carcinogenesis." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429195549.
Full textMeglia, Guillermo Esteban. "Nutrition and immune response in periparturient dairy cows : with emphasis on micronutrients /." Uppsala : Dept. of Obstetric and Gynaecology, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v170.pdf.
Full textWeeden, Allisha Marie. "Associations among dietary supplement use, dietary intake, and chronic health conditions of older adults." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/893.
Full textNelson, Chailyn. "Dietary Folate, Other B-Vitamins and Incident Alzheimer's Disease: The Cache County Memory, Health, and Aging Study." DigitalCommons@USU, 2008. https://digitalcommons.usu.edu/etd/110.
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