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Relevant bibliographies by topics / Vitamin B6

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Academic literature on the topic 'Vitamin B6'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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Journal articles on the topic "Vitamin B6"

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Sugibayashi, Kenji, Yuya Yoshida, Ryuichiro Suzuki, Kota Yoshizawa, Kenji Mori, Shoko Itakura, Kozo Takayama, and Hiroaki Todo. "Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both Vitamins." Pharmaceutics 12, no. 5 (May 6, 2020): 427. http://dx.doi.org/10.3390/pharmaceutics12050427.

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A highly viscous substance was prepared by evaporating an ethanol solution containing two hydrophilic vitamins; vitamin C, and vitamin B6. The viscous substance and physical mixture of the two vitamins were tested using a differential scanning calorimeter and an X-ray diffractometer. The highly viscous substance was found to be a liquid crystal (LC) made of these two hydrophilic vitamins. Determination by proton nuclear magnetic resonance measurement suggested that intramolecular hydrogen bonding in vitamin B6 was eliminated by the LC formation. This LC compound showed high solubility in 1,3-butanediol (almost 87%). Much higher skin permeation of both vitamin C and B6 was also observed from the LC compound than that from the physical mixture. The present LC compound containing vitamin C and vitamin B6 may be useful for pharmaceutical and cosmeceutical applications.

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LEKLEM, JAMES E. "Vitamin B6." Nutrition Today 23, no. 5 (September 1988): 4–10. http://dx.doi.org/10.1097/00017285-198809000-00001.

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Jacobs, Peter, and Lucille Wood. "Vitamin B6." Disease-a-Month 49, no. 11 (November 2003): 666–72. http://dx.doi.org/10.1016/j.disamonth.2003.09.008.

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LEKLEM, JAMES E. "Vitamin B6." Annals of the New York Academy of Sciences 669, no. 1 (September 1992): 34–41. http://dx.doi.org/10.1111/j.1749-6632.1992.tb17087.x.

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Bender, David A. "Vitamin B6." Nutrition & Food Science 97, no. 4 (August 1997): 128–33. http://dx.doi.org/10.1108/00346659710179642.

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Ekanayake, Athula, and Philip E. Nelson. "An in vitro method for estimating biologically available vitamin B6 in processed foods." British Journal of Nutrition 55, no. 2 (March 1986): 235–44. http://dx.doi.org/10.1079/bjn19860030.

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1. An in vitro method which used enzymic digestion of the food matrix to release biologically available vitamin B6 is described.2. Vitamin B6-fortified liquid model foods were thermally processed. After these foods had been freeze-dried, one part was subjected to enzymic hydrolysis at pH 2.0 with pepsin (EC 3.4.23.1) followed by a hydrolysis at pH 8.0 with pancreatin. The vitamins that were found in the supernatant fraction, after an acidified methanol treatment of the hydrolysate, were estimated by high-performance liquid chromatography (HPLC). The other part was given to rats who were kept on a vitamin B6-depleted diet.3. The biologically available vitamin B6 content of the processed model foods, as determined by rat bioassay, showed good correlation with the vitamin B6 determined by HPLC.4. It has proved possible to use this in vitro, two-stage enzymic digestion system followed by HPLC determination to determine biologically available vitamin B6 in vitamin B6-fortified processed model foods.

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El-Kholy, Mohamed Soliman, Zenat Abd El-Gawad Ibrahim, Mohamed Mamdoh El-Mekkawy, and Mahmoud Alagawany. "Influence of in Ovo Administration of Some Water-Soluble Vitamins on Hatchability Traits, Growth, Carcass Traits and Blood Chemistry of Japanese Quails." Annals of Animal Science 19, no. 1 (January 1, 2019): 97–111. http://dx.doi.org/10.2478/aoas-2018-0041.

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AbstractA total of 450 fertile Japanese quail eggs were used to determine the impacts of in ovo administration of water-soluble vitamins (C, B6 and B12) on the growth performance, carcass traits, hematological and biochemical blood parameters as well as the immune response of Japanese quails. On the 7th day of incubation, the eggs were allocated to five groups: un-injected, 0.1 ml/egg saline, 1 mg/egg vitamin C, 150 µg/egg vitamin B6 and 20 µg/egg vitamin B12. The percentage of early embryonic mortality was increased (P≤0.001) in all treated groups versus the control group. Chicks that hatched from eggs injected with 1 mg/egg vitamin C exhibited a significantly greater (P≤0.05) live body weight (LBW) than those from the control and saline groups. During 0–2 weeks of age, the chicks hatched from eggs injected with vitamins displayed better feed conversion than the positive or negative controls. In ovo injection of vitamins had no significant effect on all carcass traits. In ovo injection with vitamins C, B6 and B12 increased plasma total protein and its fractions compared with the control. Plasma levels of total lipids and cholesterol were decreased in chicks hatched from eggs injected with 1 mg/egg vitamin C, 150 µg/egg vitamin B6 or 20 µg/egg vitamin B12 compared with those hatched from control eggs. Plasma T3 and T4 were increased in chicks hatched from eggs injected with vitamin C, vitamin B6 and vitamin B12. The relative weights of the bursa of Fabricius and thymus were significantly (P=0.002 or 0.003) increased in the birds hatched from eggs injected with vitamins compared with those in the control or saline group. Thus, in ovo injection of vitamins C, B6 and B12 improved the blood profile and immune response of Japanese quail.

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Fenti, Fenti, Agustinus Widodo, and Jamaluddin Jamaluddin. "ANALYSIS OF VITAMIN B-COMPLEX OF EEL FISH (ANGUILLA MARMORATA (Q.) GAIMARD) ON ELVER PHASE ORIGIN LAKE POSO." Ghidza: Jurnal Gizi dan Kesehatan 2, no. 2 (January 10, 2019): 49. http://dx.doi.org/10.22487/gjgk.v2i2.11321.

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Background & Objective: Vitamins are complex organic substances that are needed by the body in small amounts, usually cannot be synthesized by the body but are important in metabolic processes one of which is vitamin B. Vitamin B consists of vitamins B1, B2, B3, B6, B9 and B12. Eel is one of the fish that has a high nutrient content, one of which is vitamin B. This study aims to determine the levels of vitamin B (B1, B2, B3, B6, B9 and B12) in Eel fish (Anguilla marmorata (Q.) Gaimard) on Elver phase from Lake Poso. Material and Methods: Determination of vitamin B1, B2, B3, B6 and B9 using HPLC (High Performance Liquid Chromatography), and vitamin B12 using LC-MS (Liquid Chromatography-Mass Spectrometry) . Results: The levels of vitamin B2, B3 and B12is 0.133 mg/100g, 1.895 mg/100g, and 0.017mg/100g, whereas in vitamin B1, B6 and B9 is not detected. Conclusion: Eel fish (Anguilla marmorata (Q.) Gaimard) on Elver phase from Lake Poso can be used as a source of vitamins B2, B3 and B12.

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Hoffmann, Jessica, Stefan Busse, Franz von Hoff, Katrin Borucki, Thomas Frodl, and Mandy Busse. "Association Between Homocysteine and Vitamin Levels in Demented Patients." Journal of Alzheimer's Disease 81, no. 4 (June 15, 2021): 1781–92. http://dx.doi.org/10.3233/jad-201481.

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Background: Although it is known that the nutritional status among elderly persons and, in particular, patients with dementia, is compromised, malnutrition that results in insufficient uptake of several vitamins is often not diagnosed. Objective: An elevated homocysteine level is a known strong risk factor for vascular dementia (VaD) and Alzheimer’s disease (AD). Several B vitamins are involved in the metabolism of homocysteine. Therefore, we investigated the serum levels of vitamin B1, vitamin B6, folate, and vitamin B12 in 97 patients with mild cognitive impairment (MCI) or different forms of dementia and 54 elderly control persons without dementia. Results: Compared to aged non-demented people, vitamins B1, B6, B12, and folate were decreased in serum of patients with AD, and patients with Lewy body dementia had reduced vitamin B12 level. Vitamin B6 was diminished in VaD. Patients with frontotemporal dementia showed no alterations in vitamin levels. Age was identified as an important factor contributing to the concentrations of vitamin B1 and B6 in serum, but not vitamin B12 and folate. Increased levels of total homocysteine were detected especially in MCI and AD. Homocysteine correlated negatively with levels of vitamins B6, B12, and folate and positively with Q Albumin. Conclusion: Our data suggest that despite increased homocysteine already present in MCI, vitamin levels are decreased only in dementia. We propose to determine the vitamin levels in patients with cognitive decline, but also elderly people in general, and recommend supplementing these nutrients if needed.

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Wang, Huakai, Longxian Li, Nan Zhang, Tuan Zhang, and Yongxi Ma. "Effects of Pelleting and Long-Term High-Temperature Stabilization on Vitamin Retention in Swine Feed." Animals 12, no. 9 (April 20, 2022): 1058. http://dx.doi.org/10.3390/ani12091058.

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The objective of this study was to study the effect of pelleting and long-term high-temperature stabilization on the retention of vitamin A, vitamin E, vitamin B2, and vitamin B6 in swine feed. Piglet diets (diet 1 and 3) were pelleted after conditioning at 83 °C for 120 s, and were high-temperature stabilized at 90 °C for 8.5 min after pelleting; the finishing pig diets (diet 2, 4, and 5) were pelleted after conditioning at 82 °C for 90 s, and were high-temperature stabilized at 85 °C for 9 min after pelleting; the samples were obtained before condition, after condition, after pelleting, and after cooling. The contents of vitamin A and vitamin E in diets 1–5 and vitamin B2, and vitamin B6 in diets 3–5 were detected. The results showed that: (1) the conditioning process had no significant effect on the retention of vitamin A, vitamin E, vitamin B2, and vitamin B6 in all experimental diets (p > 0.05); (2) the pelleting process and high-temperature stabilization process after pelleting had different degrees of influence on vitamins, among which the stabilization process had a more significant effect on the retention of vitamins. After pelleting and long-term high-temperature stabilization, the retention of vitamin A, vitamin E, and B2, and vitamin B6 were 68.8–77.3%, 56.9–90.1%, 63.8–70.3%, and 60.1–67.0%, respectively. In the process of pelleting and long-term high-temperature stabilization, the retention of vitamin A, vitamin E, vitamin B2, and vitamin B6 in the feed were significantly reduced (p < 0.05). Therefore, vitamin loss during high temperature and over a long period of time is worth considering, and vitamins must be over-supplemented.

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Dissertations / Theses on the topic "Vitamin B6"

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KUZUYA, FUMIO. "Vitamin B6 and Arteriosclerosis." Nagoya University School of Medicine, 1993. http://hdl.handle.net/2237/17526.

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Tambasco, Studart Marina. "Analysis of vitamin B6 biosynthesis in Arabidopsis thaliana /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17120.

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Studart, Marina Tambasco. "Analysis of vitamin B6 biosynthesis in Arabidopsis thaliana." kostenfrei, 2007. http://e-collection.ethbib.ethz.ch/view/eth:29544.

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Gandhi, Amit. "VITAMIN B6 METABOLISM AND REGULATION OF PYRIDOXAL KINASE." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/2008.

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Pyridoxal 5'-phosphate (PLP) is the cofactor for over 140 vitamin B6 (PLP)-dependent enzymes that are involved in various metabolic and biosynthetic pathways. Pyridoxal kinase (PL kinase) and pyridoxine 5’-phosphate oxidase (PNP oxidase) are the two key enzymes that metabolize nutritional forms of vitamin B6, including pyridoxal (PL), pyridoxine (PN), and pyridoxamine (PM) to the active cofactor form, PLP. Disruption of the PLP metabolic pathway due to mutations in PNP oxidase or PL kinase result in PLP deficiency, which is implicated in several neurological pathologies. Several ingested compounds are also known to result in PLP deficiency with concomitant neurotoxic effects. How these mutations and compounds affect B6 metabolism is not clearly understood. On the other hand, an emerging health problem is the intake of too much vitamin B6 as high doses of the reactive PLP in the cell exhibits toxic effects, including sensory and motor neuropathies. The overall aim of this research is to understand the catalytic function of PL kinase and the regulatory pathway of PLP metabolism. Using site-directed mutagenesis (Asp235Asn, Asp235Ala), kinetic and structural studies, we have shown that Asp235 may play a catalytic role in PL kinase phosphorylation activity. We also show that human PL kinase binds its substrates, PL and MgATP synergistically, and that the enzyme requires Na+ (or K+) and Mg2+ for its activity. Using kinetic study, we show severe induced MgATP substrate inhibition of PL kinase in the presence of its product, PLP, and we postulate this to be due to the formation of a non-productive ternary complex (Enzyme•PLP•MgATP). Consistently, our crystal structure of human PL kinase (2.1 Å) co-crystallized with MgATP and PLP showed both MgATP and PLP trapped at the active site. Our hypothesis is that this abortive ternary complex might be a physiological process, and that PL kinase uses this mechanism to self-regulate its activity. Our inhibition studies show theophylline, a bronchodilator as a mixed competitive inhibitor of human PL kinase with Ki of 71 μM. Our structural study (2.1 Å) shows theophylline bound at the substrate, PL binding site of human PL kinase. We also identified several potential PL kinase inhibitors from the DrugBank Chemical Compound database. Some of these compounds, including enprofylline, theobromine, caffeine, and lamotrigine, which incidentally exhibit similar neurotoxic effects as theophylline, show significant inhibitory effect on human PL kinase. Further studies are also planned to investigate the effect of these drugs on vitamin B6 metabolism in vivo.

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Desai, Jigarkumar. "Pyridoxal Kinase: Its Role in Vitamin B6 Metabolism." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2254.

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Pyridoxal kinase (PL kinase) and pyridoxine 5’-phosphate oxidase (PNP oxidase) are the two vitamin B6 salvage enzymes involved in metabolism of the primary inactive vitamin B6 (pyridoxal, pyridoxine and pyridoxamine) into the active cofactor form, pyridoxal 5’-phosphate (PLP). PLP, arguably the most important vitamin, is required by numerous vitamin B6 (PLP-dependent) enzymes as a co-factor. These enzymes serve vital roles in the metabolism of glucose, lipids, amino acids, heme, DNA/RNA and many neurotransmitters. High levels of vitamin B6 are linked to neurotoxicity, due to the non-specific interactions of PLP with non-B6 proteins. This problem is controlled, in part, by maintaining a low in vivo concentration of free PLP (~1 μM); raising the intriguing question of how the cell regulates, as well as, supplies sufficient PLP to meet the requirements of B6 enzymes. Similar to PLP excess, PLP deficiency, due to mutations in PL kinase and PNP oxidase or drug-induced inhibition of their activity, has been implicated in many pathological conditions. The objective of this study is to elucidate the mechanisms underlying PLP regulation by PL kinase, and its subsequent transfer to dozens of PLP-dependent enzymes. A second objective is to gain valuable information into whether a missense mutation (S261F) in PL kinase could affect the enzyme activity and/or structure. A third objective is to understand how vitamin B6 metabolism by PL kinase is disrupted by the neurotoxic compound, ginkgotoxin. The mutant (hPL kinase S261F) was obtained using site-directed mutagenesis. It was then expressed, purified and analyzed by circular dichroism, fluorescence spectroscopy, enzyme kinetics and native-PAGE. Our results showed no considerable differences between wild-type enzyme and the mutant, suggesting the mutation to be non-pathogenic. PLP was found to inhibit PL kinase by binding to the substrate PL site in the presence of substrate MgATP to form an abortive ternary complex (PL kinase-PLP-MgATP). The physiological significance of this ternary complex was also analyzed and it was found to be a source of PLP transfer to apo B6 enzymes. Enzyme kinetics, affinity chromatography and fluorescence polarization techniques were used to test our hypothesis that the reactive PLP is transferred from PL kinase to apo-B6 enzymes via channeling. Channeling should provide an efficient and protected way for PLP transfer from the kinase or oxidase to apo-B6 enzymes. Our results provide a strong support to the channeling mechanism. Ginkgotoxin was found to be a competitive inhibitor of PL kinase with a Ki of 18 μM. X-ray crystallographic analysis of its binding mode to PL kinase confirmed its binding to the substrate PL site of the enzyme. A unique hydrophobic interaction between its lipophilic side chain 4’-OCH3 and nearby Tyr127 and Val231, in addition to the conserved PL binding interactions, was found to be responsible for its higher affinity to the enzyme.

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Van, der Westhuizen Christian Abraham. "Kinetic studies of vitamin B6 metabolism in humans." Diss., University of Pretoria, 2001. http://hdl.handle.net/2263/22786.

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The primal aim of this thesis was to establish whether kinetic aspects of vitamin B6 metabolism predispose to earlier observed racial differences found in plasma pyridoxal-5'-phosphate (PLP). The active forms of vitamin B6 namely plasma PLP and pyridoxal (PL) as well as the three enzymes expressed in the erythrocyte involved in B6 metabolism, PL kinase, PLP phosphatase and pyridoxamine -5'- phosphate (pyridoxine -5'- phosphate) [PMP(PNP) ] oxidase were measured by high performance liquid chromatography. Phase one supported earlier experimental evidence and lower plasma PLP concentrations were found in blacks in a group of200 male volunteers recruited from the South African National Defence Force (SANDF). The respective enzyme activities involved in vitamin B6 metabolism, from the same test subjects, suggested similar PLP production from PMP and PL as well as PLP dephosphorylation which result in the release of PL into the circulating fluid. Since applied exclusion criteria eliminated the majority of biochemical, physiological, genetical - and disease related factors that influence vit B6 status, dietary factors and individual preferences regarding food intake, were most likely to be responsible for the significantly lower circulating plasma PLP encountered in blacks. Phase two compared pharmacokinetic parameters between 7 black - and 9 white test subjects recruited from the South African Police Services after a single 10 mg oral supplement ofpyridoxine hydrochloride. Statistical analysis of the parameters elimination half-life, elimination rate constant, clearance, volume of distribution, mean residence time, maximum peak concentration and time to maximum peak concentration failed to demonstrate any significant differences between the two groups. These results suggest consistent appearance rate, distribution and metabolism for the metabolites PLP and PL in the study population. A tendency in slower appearance rate, for both the metabolites PLP and PL, were observed in blacks and needs to be investigated further. The end product of vitamin B6 metabolism, 4-pyridoxic acid, which was expressed in terms of 24 hour urine volume, again failed to illustrate any significant differences between blacks and whites. These results suggested similar excretion properties in my population study. Furthermore, the pharmacokinetic parameters calculated for plasma PLP and PL respectively, were found to display one-compartment - and two-compartment pharmacokinetic model characteristics. This mono- and bi exponential elimination characteristics displayed by PLP and PL respectively could be of value in future research efforts in terms of sampling time. The distribution half-life can be determined by the calculation of two-compartment macro-rate constants. Fasting blood-samples should be collected when true baseline values are needed in the case of PL. Following vit B6 supplementation, one should allow at least 5 times the distribution half-life (5-6 hr in the case of PL) before blood-sampling in order to achieve true pharmacological response. Phase three of this study was conducted to illustrate the metabolic interplay ofthe enzymes PL kinase and PMP (PNP) oxidase involved in PLP production. The kinetic parameters, Michaelis- Menten constant and maximum velocity rate, at varying substrate concentrations, for the enzymes PL kinase and PMP (PNP) oxidase, were compared in 14 white - and 14 black male test subjects recruited from the SANDF. Both the average Michaelis-Menten constant and maximum velocity rate were higher in whites, but these differences were not statistically significant. The high individual variability for both parameters calculated, can possibly be ruled out if a crystalline enzyme form is used and should be investigated further.
Dissertation (MSc (Chemical Pathology))--University of Pretoria, 2006.
Chemical Pathology
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Speitling, Annette. "Wirkungen akut und chronisch hochdosierter Vitamin-B6-Gaben : biokinetische Untersuchungen am Menschen /." Giessen : Wiss. Fachverl, 1991. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=003444484&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Consiglieri, Vladi Olga. "Doseamento da vitamina B6 por espectrofotometria derivada no ultravioleta." Universidade de São Paulo, 1992. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-10072008-170738/.

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Uma metodologia rápida e seletiva foi desenvolvida para a quantificação da piridoxina em medicamentos. O método foi padronizado para aplicação da espectrofotometria derivada no ultravioleta na análise direta da vitamina em preparações multivitamínicas sólidas (cápsulas) e líquidas (solução oral e injetável). As interferências do espectro UV convencional devidas aos excipientes (veículos) e demais fármacos presentes foram eliminados. As retas de calibração foram calculadas, obtendo-se, para a derivada de 1ª ordem, o coeficiente de correlação linear de 0.99997. Os resultados foram estatisticamente estudados e determinaram-se o desvio padrão, coeficiente de variação e intervalo de confiança. O método foi empregado na análise de amostras comerciais e simuladas e os resultados, quando comparados com aqueles provenientes da aplicação do método da Farmacopéia Americana XXII rev., evidenciaram nítidas vantagens quanto à exatidão e precisão, além da facilidade operacional.
A rapid and selecrive method for rhe dererminarion of pyridoxine in pharmaceuticals has been described. The procedure has been developed using direct UV first-derivative spectrofotometry in solid and liquid preparations (tablets, oral solution and injection). Spectral inrerferences from formulation excipienrs and other drugs in simple UV spectrophotometric methods have been eliminated by the application of the proposed method. Calibration curves have been made and the correlation coefficienr for. the first-order derivative was 0,99997. Standard deviation, coefficient of variation and confidence interval were calculated. The method was applied in the analysis of commercial and simulated samples. The results when compared with those obtained by using the USP 22nd. ed. official method shows clear advanrages related to accuracy, precision and practical application.

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Pittaya, Kanchanapakonchai Amnuay Thithapandha. "Effects of vitamin B6 on CC14 toxicities in rats /." abstract, 1986. http://mulinet3.li.mahidol.ac.th/thesis/2529/29E-Pittaya-K.pdf.

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Footitt, E. J. "Vitamin B6 and serotonin metabolism in neurological disorders of childhood." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1413008/.

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Pyridoxal 5’-phosphate (PLP) is the active form of vitamin B6 in man where it functions as a cofactor for more than 140 enzyme catalysed reactions. Several inherited diseases characterised by seizures have been described which result in an intracellular deficiency of PLP; laboratory measurement of B6 forms an important element in the diagnosis and monitoring of these disorders. A review of PLP measured by HPLC in CSF from patients with neurological disorders showed that variance is greater than indicated by previous studies and the age-related reference limit was revised. This thesis also describes the metabolic disorders that may lead to PLP depletion and examines the relationship of CSF PLP to sulphite accumulation, medications and seizures in patient groups. B6 exists as six different vitamers and is catabolised to 4-pyridoxic acid for urinary excretion. An LC-MS/MS method was developed which could measure all vitameric forms in plasma. Its application to children with B6 responsive seizure disorders showed that patients with inborn errors of metabolism have characteristic B6 profiles which allow them to be differentiated from each other and control populations. PLP is the cofactor for aromatic L-amino acid decarboxylase (AADC) which catalyses the final step in serotonin biosynthesis. This thesis tested the hypothesis that hyperserotonaemia observed in some patients with autism is related to an abnormality in this pathway by investigating the relationship between plasma B6 vitamers, AADC activity and whole blood serotonin in a group of patients and controls. Plasma AADC activity was significantly reduced in autistic subjects; this is considered in the context of current biochemical and molecular understanding and its possible relevance to disease mechanisms is discussed.

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Books on the topic "Vitamin B6"

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1928-, Dakshinamurti Krishnamurti, New York Academy of Sciences., and International Multidisciplinary Conference on Vitamin B6 (1989 : Philadelphia, Pa.), eds. Vitamin B6. New York, N.Y: New York Academy of Sciences, 1990.

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Jean, Pamplin, ed. Vitamin B6 therapy. Garden City Park, N.Y: Avery Pub. Group, 1999.

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Korpela, Timo K., and Philipp Christen, eds. Biochemistry of Vitamin B6. Basel: Birkhäuser Basel, 1987. http://dx.doi.org/10.1007/978-3-0348-9308-4.

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Marino, G., G. Sannia, and F. Bossa, eds. Biochemistry of Vitamin B6 and PQQ. Basel: Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7393-2.

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Gaby, Alan. B6, the natural healer. New Canaan, Conn: Keats Pub., 1987.

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Ellis, John Marion. Diabetes, new therapies: Clinically proven usage of vitamin B6. [S.l.]: J.M. Ellis, 1995.

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Barnes, N. M. A study of vitamin B6 in total parenteral nutrition. Birmingham: Aston University. Department of Pharmaceutical Sciences., 1989.

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David, Dolphin, Poulson Rozanne, and Avramović Olga, eds. Vitamin B6 pyridoxal phosphate: Chemical, biochemical, and medical aspects. New York: Wiley, 1986.

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Nolan, Marie-Louise. Studies on the effects of pyridoxal-5'-phosphate on the aggregation of blood platelets. Dublin: University College Dublin, 1997.

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U, Gerbershagen H., Zimmermann M. 1933-, and World Congress on Pain. (5th : 1987 : Hamburg, Germany), eds. B-vitamins in pain: Hamburg, 2nd August 1987. Frankfurt am Main: PMI Verlag, 1988.

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Book chapters on the topic "Vitamin B6"

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Bährle-Rapp, Marina. "Vitamin B6." In Springer Lexikon Kosmetik und Körperpflege, 585. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_11067.

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Winter, Jerrold. "Vitamin B6." In True Nutrition, True Fitness, 115–28. Totowa, NJ: Humana Press, 1991. http://dx.doi.org/10.1007/978-1-4612-0479-4_9.

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Jomaa, H. "Vitamin B6." In Springer Reference Medizin, 2462–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3264.

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Jomaa, H. "Vitamin B6." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1–2. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_3264-1.

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Ball, G. F. M. "Vitamin B6." In Bioavailability and Analysis of Vitamins in Foods, 361–407. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-3414-7_10.

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Marks, John. "Vitamin B6." In The Vitamins, 155–58. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-7321-6_24.

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da Silva, Vanessa R., Katelyn A. Russell, and Jesse F. Gregory. "Vitamin B6." In Present Knowledge in Nutrition, 307–20. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781119946045.ch20.

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Du, Li-Da, You-Wen Zhang, and Guan-Hua Du. "Vitamin B6." In Natural Small Molecule Drugs from Plants, 647–51. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8022-7_104.

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Balemans, Wendy, Wim Van Hul, Marian Valko, Jan Moncol, Lee A. Denson, Maria Mela, Ulrich Thalheimer, et al. "Vitamin B6." In Encyclopedia of Molecular Mechanisms of Disease, 2217–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_1853.

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Plecko, Barbara, and Eduard A. Struys. "Vitamin B6-Dependent and Vitamin B6-Responsive Disorders." In Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases, 577–91. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-67727-5_34.

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Conference papers on the topic "Vitamin B6"

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Randi, A. M., E. Sacchi, and M. Cattaneo. "ORALLY ADMINISTERED VITAMIN B PROLONGS THE BLEEDING TIME AND INHIBITS PLATELET AGGREGATION IN HUMAN VOLUNTEERS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643446.

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It is known that mM concentrations of vitamin B6 inhibit human platelet aggregation and fibrin formation in vitro. There are very few and controversial data on the ex vivo effects of vitamin B6 on hemostatic parameters. We evaluated the effects of oral administration of vitamin B6 on bleeding time (BT), fibrin formation, platelet aggregation (PA) and the release reaction (RR). Vitamin B6 300 mg/day p.o., was given to 18 healthy volunteers (8 M, 10 F, aged 23-35) for 8 days. BT was measured before the first dose (Baseline), 2 hr after the first (Day 1) and the last dose (Day 8). In 7 subjects BT was measured also 7 days after the suspension of the drug (Day 15). Before and 2 hr after the first dose, prothrombin time (PT), partial thromboplastin time (PTT), thrombin time (TT), PA and the RR induced by different concentrations of ADP, PAF-acether, collagen (coll), epinephrine (epi), arachidonate (AA) were studied. BT was significantly prolonged after vitamin B6 administration, and returned to baseline values 7 days after suspension of the drug. PA and the RR induced by 1 uM ADP, 1 ug/ml coll or 5 uM epi were significantly inhibited 2 hours after vitamin B6 administration. Vitamin B6, however, did not affect PA or the RR induced by 0.2-2 uM PAF-acether, 2 uM ADP, 1 mM AA, 2 ug/ml coll, nor did it affect PT, PTT or TT. These data show that orally administered vitamin B impairs primary hemostasis, but does not affect fibrin 6 formation, as measured with standard coagulation tests.

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Hildebrandt, Martin, and Kai-Nils Pargac. "P 518. Vitamin B6-Dependent West’s Syndrome: An Unexplained Case." In Abstracts of the 44th Annual Meeting of the Society for Neuropediatrics. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1675953.

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Yang, Hui, Xue Xiao, Xuesong Zhao, Lan Hu, Caofang Lv, and Zhangkun Yin. "Intrinsic fluorescence spectra characteristics of vitamin B1, B2, and B6." In Selected Proceedings of the Photoelectronic Technology Committee Conferences held June-July 2015, edited by Shenggang Liu, Songlin Zhuang, Michael I. Petelin, and Libin Xiang. SPIE, 2015. http://dx.doi.org/10.1117/12.2216038.

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Gylling, Björn, Robin Myte, Jörn Schneede, Göran Hallmans, Jenny Häggström, Ingegerd Johansson, Arve Ulvik, et al. "Abstract 4291: Vitamin B6 biomarkers and colorectal cancer: Modifications by time." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4291.

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Wei, Esther K., Jung Eun Lee, Edward Giovannucci, Charles Fuchs, Jacob Selhub, Susan E. Hankinson, Meir Stampfer, Walter Willett, and Jing Ma. "Abstract B102: Plasma vitamin B6 and the risk of colorectal cancer in three large prospective cohorts." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Dec 6–9, 2009; Houston, TX. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-09-b102.

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Zhang, Xuehong, Jung Eun Lee, Jing Ma, Youjin Je, Kana Wu, Walter C. Willett, Charles S. Fuchs, and Edward L. Giovannucci. "Abstract 628: Prospective cohort studies of vitamin B6 intake and colorectal cancer incidence: Modification by time." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-628.

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Chen Jia-li. "Clinical observation about 40 cases of primary dysmenorrheal with the treatment of Marvelon & Vitamin B6." In 2011 International Symposium on Information Technology in Medicine and Education (ITME 2011). IEEE, 2011. http://dx.doi.org/10.1109/itime.2011.6130889.

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Wang, C., Y. Ding, L. Li, Q. Mei, A. Wang, D. Duan, and H. Zeng. "P2EC.1 - An electrochemical sensor based on NiAl-layered double/graphene oxide hydroxide for detection of Vitamin B6." In 17th International Meeting on Chemical Sensors - IMCS 2018. AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany, 2018. http://dx.doi.org/10.5162/imcs2018/p2ec.1.

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Kalser, J., B. Plecko, F. Giuliano, and B. K. Bölsterli. "A Case of Vitamin-B6-Dependent Disorder Presenting with Abnormal Eye–Head Movements and Infantile Spasms without Hypsarrhythmia." In Abstracts of the 48th Annual Meeting of the SENP (Société Européenne De Neurologie Pédiatrique). Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1746216.

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Khudhair, Ahmed F., Shaymaa I. Saeed, and Haitham D. Hanoon. "Ultra-sonic extraction of vitamin B6 from aqueous solution using a multi adsorbent layer solid phase graphene oxide." In INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING ICCMSE 2021. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0114865.

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Reports on the topic "Vitamin B6"

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Ingersoll, D. T., J. E. White, R. Q. Wright, H. T. Hunter, C. O. Slater, N. M. Greene, R. W. Roussin, and R. E. MacFarlane. Production and testing of the VITAMIN-B6 fine group and the BUGLE-93 broad-group neutron/photon cross-section libraries derived from ENDF/B-VI nuclear data. Office of Scientific and Technical Information (OSTI), January 1995. http://dx.doi.org/10.2172/10108149.

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Zhu, Min, Xiujing Liu, Changhui Zhou, and Juan Li. Effect of sodium cantharidinate/vitamin B6 injection on survival, liver function, immune function, and quality of life in patients with hepatocellular carcinoma: protocol for a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0121.

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White, J. E. Production and Testing of the VITAMIN-B6 Fine Group and the BUGLE-93 Broad-Group Neutron/Photon Cross-Section Libraries Derived from ENDF/B-VI Nuclear Data. Office of Scientific and Technical Information (OSTI), April 2001. http://dx.doi.org/10.2172/779795.

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