Relevant bibliographies by topics / Vitamin B12

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Vitamin B12'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 July 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Vitamin B12.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Vitamin B12"

1

Lai, Jun S., M. Na’im Mohamad Ayob, Shirong Cai, Phaik Ling Quah, Peter D. Gluckman, Lynette P. Shek, Fabian Yap, et al. "Maternal plasma vitamin B12 concentrations during pregnancy and infant cognitive outcomes at 2 years of age." British Journal of Nutrition 121, no. 11 (April 2, 2019): 1303–12. http://dx.doi.org/10.1017/s0007114519000746.

Full text
Abstract:
AbstractEvidence on long-term influences of maternal vitamin B12 deficiency or concentrations on infant cognition is limited. We examined associations between maternal plasma vitamin B12 and cognitive development in 24-month-old infants. Maternal plasma vitamin B12 concentrations were measured at 26–28 weeks’ gestation; infant cognitive development was assessed with the Bayley Scales of Infant and Toddler Development-III at 24 months, for 443 mother–infant pairs from the Growing Up in Singapore Towards Healthy Outcomes cohort. Linear regressions adjusted for key confounders examined associations of maternal vitamin B12 with cognitive, receptive and expressive language, fine and gross motor subscales. Co-occurrence of maternal vitamin B12 with folate or vitamin B6 insufficiencies on child’s cognition was explored. Average maternal plasma vitamin B12 concentrations was 220·5 ± 80·5 pmol/l; 15 % and 41 % of mothers were vitamin B12 deficient (<148 pmol/l) and insufficient (148–220·9 pmol/l), respectively. Infants of mothers with vitamin B12 deficiency had 0·42 (95 % CI −0·70, −0·14) sd lower cognitive scores, compared with infants of mothers with sufficient vitamin B12. Co-occurrence of maternal vitamins B12 and B6 insufficiencies was associated with 0·37 (95 % CI −0·69, −0·06) sd lower cognitive scores in infants compared with infants of mothers sufficient in both vitamins. No significant associations were observed with other subscales. Study findings suggest the possible need to ensure adequate vitamin B12 during pregnancy. The impact of co-occurrence of maternal B-vitamins insufficiencies on early cognitive development warrants further investigation.
APA, Harvard, Vancouver, ISO, and other styles
2

Fahad Aldaihani, Saad. "VITAMIN DEFICIENCY AND FOOD SUPPLEMENTS." International Journal of Advanced Research 9, no. 12 (December 31, 2021): 540–52. http://dx.doi.org/10.21474/ijar01/13941.

Full text
Abstract:
Vitamins are a heterogeneous group of organic compounds that help ensure the human bodys wellbeing and function. This paper introduces the importance of all vitamins, both water-soluble and fat-soluble, as well as problems deriving from their deficiency. Additionally, vitamin supplements as part of treating vitamin deficiency, and possible harmful effects on the human body areshowcased. The main focus of the paper is on the vitamin B complex, and vitamin B12 specifically. The benefits of vitamin B12, as well as its action in the human body and the noxious effects of any lack of vitamin B12 in the human body, are also discussed. Some of the health conditionsan individual may need to face when they have vitamin B12 deficiency include neural tube defects, Alzheimers disease, depression, and megaloblastic anaemia, which are also introduced and further discussed, in terms of symptomatology, causes and suggested treatment. The toxicity of vitamin B12 is also introduced, and possible causes for vitamin B12 deficiency are showcased.
APA, Harvard, Vancouver, ISO, and other styles
3

Yadav, Roopesh Kumar, Sudhanshu Mishra, and Deepti Jain. "Methylcobalamine (Vitamin B12): Water Soluble Vitamin with Various Pharmacological Aspect." Journal of Drug Delivery and Therapeutics 11, no. 1 (January 15, 2021): 130–37. http://dx.doi.org/10.22270/jddt.v11i1.4488.

Full text
Abstract:
Vitamin B12 is a water-soluble vitamin that plays a key role in the brain's proper functioning and nervous system, in blood flow, and in reducing weakness and tiredness. In their food, most people get adequate vitamin B12, but in some health conditions (e.g. inadequate sleep, stomach/intestinal disorders, inflammation, cancer), there could be a shortage. If left unchecked, severe Vitamin B12 deficiency results in anemia and nerve damage. Vitamin B12 deficiency is typically treated using parenteral and oral dosage formulations, but absorption and compliance problems are involved with these routes of administration. Most significantly, the function of this missing intrinsic factor has been shown to assist in vitamin B12 absorption and a deficiency known as pernicious anaemia. Vitamin B12 is only partially absorbed when delivered by mouth to patients with pernicious anemia, but hematologically re-absorbed in patients with pernicious anemia. Parenteral administration of the extrinsic element will treat pernicious anaemia satisfactorily. There are several roles and advantages of vitamin B 12 in the human body with therapeutic effects also. Keywords: Water Soluble Vitamins, Methylcobalamine, Vitamin B12, Pernicious Anaemia.
APA, Harvard, Vancouver, ISO, and other styles
4

Mihaljev, Željko, Milica Živkov Baloš, and Sandra Jakšić. "POSSIBILITY OF DETERMINING VITAMIN B12 IN VITAMIN PREMIXES AND FEED ADDITIVES USING AAS METHOD." Archives of Veterinary Medicine 1, no. 2 (December 29, 2008): 75–80. http://dx.doi.org/10.46784/e-avm.v1i2.233.

Full text
Abstract:
Since vitamin B12 has important metabolic functions, but is unable sufficiently to synthesize into organisms of domestic animals (especially non-ruminants), special attention is given to adding B12 into feed. The needs for this vitamin are provided through vitamin premixes, so determining the quantity of B12 in the samples is of utmost importance. When standard chemical methods are applied extraction and purification are required. In this paper is described a method where the content of B12 in premix with high level of different vitamins is determined through an indirect method: measuring the level of cobalt using atomic absorption spectrophotometry. The content of B12 was determined from the content of cobalt. The obtained results show that in the samples of pure B12 vitamin (used as an additive to feed) the measured values were lesser than 2% comparing to the expected values. In vitamin premixes the measured values of group B and vitamin premixes of vitamin B group and other (A, D, E) vitamins, the measured values differed from those given on the declaration, and the difference was lesser than 5%. The obtained results point that determining vitamin B12 by measuring cobalt content using AAS method is a fast, accurate and simple method that can be applied in examining all the feed samples.
APA, Harvard, Vancouver, ISO, and other styles
5

Koprivica, Marko, Jelena Bjelanovic, and Radmila Velicki. "The effects of vitamin B12 deficiency." Medical review 74, no. 11-12 (2021): 391–95. http://dx.doi.org/10.2298/mpns2112391k.

Full text
Abstract:
Vitamin B12 is one of the most important B vitamins. This vitamin has an important role in cellular metabolism and is also associated with folate and vitamin B6 metabolism. Vitamin B12 deficiency occurs as a result of some diseases, the use of certain medications, or inadequate nutrition. It primarily affects the elderly and women, but is also common among the pediatric population. The B12 deficiency mostly affects the functions of the nervous and hematopoietic systems but it can also affect the skin, heart, bones, and eyes. The treatment of vitamin B12 deficiency includes oral or intramuscular vitamin B12 supplementation according to different treatment regimens.
APA, Harvard, Vancouver, ISO, and other styles
6

Ismael Ibrahim, Gulzar, Hemn Jameel Majeed, Pshtiwan Abdullah Yousif, and Saman Muhsin Abdulkareem. "Association between Serum Levels of Vitamin D, Vitamin B12 and Folate with Oxidative Biomarkers in Diabetic Type 2 Patients in People in Erbil City: A Case-Control Study." Diyala Journal of Medicine 19, no. 2 (December 15, 2020): 200–207. http://dx.doi.org/10.26505/djm.19025660915.

Full text
Abstract:
Background: Diabetes mellitus is the largest endocrine disorder in the world that refers to chronic hyperglycemia caused by impairment in both insulin secretion and action. Folate, vitamin B12, and vitamin D deficiency are related to the prevalence of type 2 diabetes mellitus. Objective: This study has been carried out to investigate the role of folate, vitamins B12, and D status during the progression of diabetic type 2 patients compared to non-diabetic control subjects. Patients and Methods: We measured the plasma levels of folate, vitamins B12, and D, along with blood glucose, HbA1c, and oxidative biomarkers in 50 diabetic type 2 patients and 50 healthy subjects used as a control group. Results: The findings revealed that the serum level of malondialdehyde (MDA) significantly increased in diabetic patients compared to healthy subjects, and the serum level of nitric oxide (NO) in T2D patients lower than in control. The concentration of vitamin D, B12, and folate in T2D patients significantly lower than non-T2D control. The results also showed a significant relationship between serum vitamin D, MDA, and NO with HbA1c, while there was an insignificant correlation between vitamin B12 and folate with HbA1c. Conclusion: The oxidative biomarkers and vitamins D, B12, and folate level can play an important role in the development and progression of T2D. Keywords: Oxidative Stress, Vitamin D, Vitamin B12, Folic acid, type 2 diabetes
APA, Harvard, Vancouver, ISO, and other styles
7

Cazacu, Nicoleta, Claudia G. Chilom, Melinda David, and Monica Florescu. "Conformational Changes in the BSA-LT4 Complex Induced by the Presence of Vitamins: Spectroscopic Approach and Molecular Docking." International Journal of Molecular Sciences 23, no. 8 (April 11, 2022): 4215. http://dx.doi.org/10.3390/ijms23084215.

Full text
Abstract:
Levothyroxine (LT4) is known for its use in various conditions including hypothyroidism. LT4 interaction with serum albumin may be influenced by the presence of vitamins. For this reason, we investigated the effect of vitamin C, vitamin B12, and folic acid on the complex of Bovine Serum Albumin with LT4 (BSA-LT4). UV-Vis spectroscopy was used to monitor the influence of vitamins on the BSA-LT4 complex. Fluorescence spectroscopy revealed a static quenching mechanism of the fluorescence of BSA-LT4 complex by the vitamin C and folic acid and a combined mechanism for vitamin B12. The interaction of vitamin C and folic acid with BSA-LT4 was moderate, while the binding of vitamin B12 was much stronger, extending the storage time of LT4 in blood plasma. Synchronous fluorescence found that the vitamins were closer to the vicinity of Trp than to Tyr and the effect was more pronounced for the binding of vitamin B12. The thermal stability of the BSA-LT4 complex was more evident, but no influence on the stability of BSA-LT4 complex was obtained for vitamin C. Molecular docking studies showed that vitamin C and folic acid bound the same site of the protein, while vitamin B12 bonded to a different site.
APA, Harvard, Vancouver, ISO, and other styles
8

Nouri, Aria, Kishan Patel, Julio Montejo, Rani Nasser, David A. Gimbel, Daniel M. Sciubba, and Joseph S. Cheng. "The Role of Vitamin B12 in the Management and Optimization of Treatment in Patients With Degenerative Cervical Myelopathy." Global Spine Journal 9, no. 3 (May 17, 2018): 331–37. http://dx.doi.org/10.1177/2192568218758633.

Full text
Abstract:
Study Design: Narrative review. Objectives: To discuss the relationship between degenerative cervical myelopathy (DCM) and vitamin B12 deficiency. Specifically, it is the aim to outline the rational for future research into assessment and therapeutic optimization of vitamin B12 in the treatment of DCM. Methods: Literature review. Results: DCM is the commonest cause of spinal cord impairment, with an average age of presentation in the sixth decade. Patients at this age have also been reported to have a high prevalence of vitamin B12 deficiency, with estimates of up to 20% in the elderly. Vitamin B12 deficiency can result in subacute combined degeneration of the spinal cord (SACD), and several case reports have pointed to patients with both DCM and SACD. Both SACD and reversible compressive injury due to DCM necessitate remyelination in the spinal cord, a process that requires adequate vitamin B12 levels. Basic science research on nerve crush injuries have shown that vitamin B12 levels are altered after nerve injury and that vitamin B12 along with dexamethasone or nonsteroidal anti-inflammatory drugs can reduce Wallerian degeneration. Furthermore, it has been suggested that a combination of B-vitamins can reduce glutamate-induced neurotoxicity. Conclusions: Given the high prevalence of clinical and subclinical vitamin B12 deficiency in the elderly, the role of vitamin B12 in myelination, and vitamin B12 deficiency as a differential diagnosis of DCM, it is important to investigate what role vitamin B12 levels play in patients with DCM in terms of baseline neurological function and whether optimization of vitamin B12 levels can improve surgical outcome. Furthermore, the routine assessment of vitamin B12 levels in patients considered for DCM surgery should be considered.
APA, Harvard, Vancouver, ISO, and other styles
9

El-Kholy, Mohamed Soliman, Zenat Abd El-Gawad Ibrahim, Mohamed Mamdoh El-Mekkawy, and Mahmoud Alagawany. "Influence of in Ovo Administration of Some Water-Soluble Vitamins on Hatchability Traits, Growth, Carcass Traits and Blood Chemistry of Japanese Quails." Annals of Animal Science 19, no. 1 (January 1, 2019): 97–111. http://dx.doi.org/10.2478/aoas-2018-0041.

Full text
Abstract:
AbstractA total of 450 fertile Japanese quail eggs were used to determine the impacts of in ovo administration of water-soluble vitamins (C, B6 and B12) on the growth performance, carcass traits, hematological and biochemical blood parameters as well as the immune response of Japanese quails. On the 7th day of incubation, the eggs were allocated to five groups: un-injected, 0.1 ml/egg saline, 1 mg/egg vitamin C, 150 µg/egg vitamin B6 and 20 µg/egg vitamin B12. The percentage of early embryonic mortality was increased (P≤0.001) in all treated groups versus the control group. Chicks that hatched from eggs injected with 1 mg/egg vitamin C exhibited a significantly greater (P≤0.05) live body weight (LBW) than those from the control and saline groups. During 0–2 weeks of age, the chicks hatched from eggs injected with vitamins displayed better feed conversion than the positive or negative controls. In ovo injection of vitamins had no significant effect on all carcass traits. In ovo injection with vitamins C, B6 and B12 increased plasma total protein and its fractions compared with the control. Plasma levels of total lipids and cholesterol were decreased in chicks hatched from eggs injected with 1 mg/egg vitamin C, 150 µg/egg vitamin B6 or 20 µg/egg vitamin B12 compared with those hatched from control eggs. Plasma T3 and T4 were increased in chicks hatched from eggs injected with vitamin C, vitamin B6 and vitamin B12. The relative weights of the bursa of Fabricius and thymus were significantly (P=0.002 or 0.003) increased in the birds hatched from eggs injected with vitamins compared with those in the control or saline group. Thus, in ovo injection of vitamins C, B6 and B12 improved the blood profile and immune response of Japanese quail.
APA, Harvard, Vancouver, ISO, and other styles
10

Mantle, David. "Nutritional supplementation for vitamin B12 and vitamin K2 deficiency following ileostomy or colostomy formation." Gastrointestinal Nursing 18, Sup4 (May 1, 2020): S12—S16. http://dx.doi.org/10.12968/gasn.2020.18.sup4.s12.

Full text
Abstract:
Most dietary vitamins and minerals are absorbed from the duodenal and jejunal sections of the small bowel. The exceptions are vitamin B12 and vitamin K2, which are absorbed from the terminal ileum and colon respectively. Patients who have undergone ileostomy or colostomy procedures are at risk of deficiency of these vitamins, with associated risk of developing anaemia and nervous system dysfunction (vitamin B12), and bone weakening and cardiovascular disease (vitamin K2). Patients should therefore be monitored for deficiency of these vitamins, which may develop over a protracted period of time. Patients lacking the terminal ileum or colon can still absorb supplemental vitamins B12 or K2 given orally, provided a sufficient loading dose is given to facilitate absorption from the remaining gastrointestinal tract.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Vitamin B12"

1

Divya, Jagasia, and Ferrando Vanesa Zanzi. "Tempeh: a tempting potential vitamin B12 treat : An exploration of legumes and vitamin B12." Thesis, Uppsala universitet, Institutionen för kostvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-255419.

Full text
Abstract:
Background: Legumes are beneficial for the environment, nutritious and coupled with various health benefits. However, they lack the essential vitamin B12 and a vitamin B12 deficiency can lead to hazardous health problems. Tempeh is a fermented legume product that has the potential of carrying vitamin B12. Aim: The aim of this thesis is to investigate consumers' awareness of vitamin B12 and explore the indications for the possibility to introduce tempeh - a fermented legume product. Method: A quantitative survey was carried out within four different areas of Stockholm using a clustering sample technique with 195 participants who were recruited outside supermarkets through convenience sampling. Results: The majority of the subjects had moderate consumption of legumes and was open to trying tempeh even though they had never heard about it. While their knowledge of vitamin B12 was limited, the biggest risk groups, vegans and the elderly, were aware that they were a risk group but only a minority of them knew the correct vitamin B12 food sources. Conclusion: The participants in this study had little knowledge about vitamin B12 food sources, deficiencies or risk groups. Since their legume consumption was regular and they were positive towards trying tempeh even though they had never heard about tempeh before, there is potential for it in the market. However, more studies are needed to research the bioavailability of vitamin B12 in tempeh even though new research gives hope that it can be a possibility.
APA, Harvard, Vancouver, ISO, and other styles
2

Zant, Ayman [Verfasser], and Rima [Akademischer Betreuer] Obeid. "Auswirkung einer mit Vitamin B12 angereicherten Zahncreme auf Plasma-Vitamin-B12 / Ayman Zant ; Betreuer: Rima Obeid." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2019. http://d-nb.info/1213294606/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Murray, Louise M. "Comparative study of vitamin B12 and holotranscobalamin or active B12 as a marker for vitamin B12 deficiency at Dr George Mukhari Hospital." Thesis, University of Limpopo (Medunsa Campus), 2012. http://hdl.handle.net/10386/774.

Full text
Abstract:
Thesis (M Med (Chemical Pathology)) -- University of Limpopo, 2012.
Abstract Aim: This study was undertaken to compare the diagnostic sensitivity and specificity of total vitamin B 12 analyses to active B 12 (holoTC) analyses in a population of patients attending the Dr George Mukhari Hospital in Pretoria. Methods: Routine serum folate, full blood count (FBC), thyroid function test, homocysteine, serum total vitamin B 12 and active B 12 analyses were performed on 30 samples. Results: Serum folate was determined in all patients and 96% of the patients had a normal folate value. When looking at the FBC results it is important to note that three times as many males as females presented with anemia (36% versus 16%). Thyroid function tests were normal in 90% of patients. When the total vitamin B 12 test was preformed only 10% of patients tested positive for vitamin B 12 deficiency, in contrast to the active B12 analyses where 16% of patients tested positive for vitamin B12 deficiency. Both tests had a diagnostic sensitivity of 50%. The diagnostic specificity for total vitamin B12 was 93% in comparison with the 86% obtained by the active B12 analyses; when homocysteine was used as the true marker for vitamin B12 deficiency. Conclusion: Diagnostic sensitivity was the same and the total vitamin B12 test's specificity was better in comparison to the active B 12 analyses. Thus the active B 12 assay cannot be recommended for routine use, since it has no benefit.
APA, Harvard, Vancouver, ISO, and other styles
4

Chen, Hong-chei. "Studies on the biosynthesis of vitamin B2 and vitamin B12 /." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487596307358381.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

McGoldrick, Helen Margaret. "Cobalamin (vitamin B12) biosynthesis in rhodobacter capsulatus." Thesis, Queen Mary, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415432.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Heilmann, Romy Monika, Niels Grützner, Christina M. Iazbik, Rosana Lopes, Seth C. Bridges, Jan S. Suchodolski, Guilermo C. Couto, and Jörg M. Steiner. "Hyperhomocysteinemia in greyhounds and its association with hypofolatemia and other clinicopathologic variables." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-213902.

Full text
Abstract:
Background: Folate and cobalamin are essential cofactors for homocysteine (HCY) metabolism. Hyperhomocysteinemia, a multifactorial condition, may reflect B vitamin deficiency and is associated with increased risk of cardiovascular disease, thrombosis, and neurodegenerative and chronic gastrointestinal diseases in humans. Hyperhomocysteinemia has been reported in Greyhounds with suspected chronic enteropathy. Objectives: To evaluate the frequencies of and the association between hypofolatemia and hyperhomocysteinemia in Greyhounds. Animals: Data and serum samples from 559 Greyhounds. Methods: Nested case-control study. The frequency of hypofolatemia in Greyhounds was determined by a laboratory database search. The relationship between hyperhomocysteinemia (measured by gas chromatography-mass spectrometry) and hypocobalaminemia and hypofolatemia was evaluated, and its frequency compared between healthy Greyhounds and Greyhounds with thrombosis or chronic diarrhea. Results: Hypofolatemia was identified in 172 of 423 (41%) Greyhounds and was more common in hypo- than in normocobalaminemic dogs (49% vs. 35%; P = .0064). Hyperhomocysteinemia was detected in 53 of 78 (68%) of Greyhounds, being more common in hypo- than in normofolatemic dogs (88% vs. 59%; P = .0175). All healthy Greyhounds, 21 of 30 (70%) of dogs with chronic diarrhea and 6 of 8 (75%) of those with thrombosis, were hyperhomocysteinemic. Serum HCY concentrations were inversely correlated with serum folate concentration (q = -0.28; P = .0386) and were positively associated with serum albumin concentration (q = 0.66; P = .0022). Conclusions and Clinical Relevance: Hyperhomocysteinemia occurs frequently in the Greyhound population. Its association with hypofolatemia suggests decreased intracellular availability of B vitamins, but the functional implications warrant further investigation. Hyperhomocysteinemia in Greyhounds potentially may serve as a spontaneous canine model to further investigate hyperhomocysteinemia in humans.
APA, Harvard, Vancouver, ISO, and other styles
7

Kowalzik, Frank. "Prophylaxe der Frühgeborenenanämie mittels Vitamin B12 und Folsäure." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=968791905.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Aydın, Osman Sarıtaş Ülkü. "Helicobacter pylori eradikasyonunun vitamin B12 eksikliği üzerine etkisi /." Isparta: SDÜ Tıp Fakültesi, 2006. http://tez.sdu.edu.tr/Tezler/TT00284.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Vogiatzoglou, Anna. "Vitamin B12 status : determinants, biomarkers and brain function." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526422.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Borley, Mark Letchford. "The uptake of vitamin B12 by unicellular algae." Thesis, Royal Holloway, University of London, 1987. http://repository.royalholloway.ac.uk/items/e6b0cd50-d50c-45ee-a723-bcf53e5d0125/1/.

Full text
Abstract:
Vitamin B12 binding and uptake by two unicellular, marine algae, the autotrophic Dunaliella primolecta and the auxotrophic Pavlova lutheri, has been studied. Features of the extracellular binders found in the culture medium of micro-algae were examined to elucidate their role. The B12 binding capacity of these proteins was shown to be proportional to cell density, and they were relatively stable for at least one month. Nevertheless, cells bind the majority of vitamin until stationary phase. Membrane-bound and intracellular cytosolic binders have also been isolated, representing around 49 and 16 % respectively of the total B12 binding capacity of cultures, 35% typically being associated with the extracellular fraction. To discover the relationship between these proteins and the nature of the uptake process, characterisation was pursued. An affinity chromatography-based purification scheme was developed for the binders, and small quantities of these proteins were purified from all three phases. Gel filtration showed uniform molecular weights in excess of 500,000, and amino acid analyses revealed similar compositions. The identification of carbohydrate components was investigated using a lectin-binding assay. However, it was not found to be possible to determine sub-unit molecular weight by SDS gelelectrophoresis, and attempts at localisation of the cellular B12 binding sites using fluorescence microscopy and electron probe micro-analysis were unsuccessful. Interestingly though, similar vitaminbinding characteristics were demonstrated for isolatedchloroplasts and intact cells of D. primolecta. Aspects of B12 and its uptake by micro-algae arereviewed, and an explanation for extracellular B12 binding proteins involving non-specific release issuggested. A general model of two-stage uptake of the vitamin by micro-algae, with a primary stage of binding to a receptor protein in the plasma membrane and a secondary phase of energy-dependent internalisation, is also proposed.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Vitamin B12"

1

Victor, Herbert, ed. Vitamin B12 deficiency. London: Royal Society of Medicine Press, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

European Symposium on Vitamin B12 and B12-Proteins (4th 1996 Innsbruck, Austria). Vitamin B12 and B12-proteins: Lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins. Weinheim: Wiley-VCH, 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

1939-, Stroiński Andrzej, ed. Comprehensive B12: Chemistry, biochemistry, nutrition, ecology, medicine. Berlin: De Gruyter, 1987.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Waters, Henry McKiness. Vitamin B12: Absorption and binding proteins. Manchester: University of Manchester, 1996.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

International Symposium on Biomedicine and Physiology of Vitamin B12. (1st 1988 London, England). Biomedicine and physiology of vitamin B12: Proceedings of the First International Symposium, Charing Cross & Westminster Medical School, University of London, 26-29 September 1988. Edited by Bhatt H. R and Linnell J. C. London: The Children's Medical Charity, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Food and Agriculture Organization of the United Nations. and World Health Organization, eds. Requirements of vitamin A, iron, folate, and vitamin B12: Report of a joint FAO/WHO expert consultation. Rome: Food and Agriculture Organization of the United Nations, 1988.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

U, Gerbershagen H., Zimmermann M. 1933-, and World Congress on Pain. (5th : 1987 : Hamburg, Germany), eds. B-vitamins in pain: Hamburg, 2nd August 1987. Frankfurt am Main: PMI Verlag, 1988.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

I͡Urkevich, A. M. Struktura, svoĭstva i mekhanizm deĭstvii͡a kobalaminovykh kofermentov. Moskva: VINITI, 1985.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Dahlfors, Agneta A. Richter. Regulation of the cobalamin biosynthetic genes in Salmonella typhimurium. Uppsala: Acta Universitatis Upsaliensis, 1994.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

D, Wright Jacqueline, and National Center for Health Statistics (U.S.), eds. Blood folate and vitamin B12: United States, 1988-95. Hyattsville, Md: U.S. Dept of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Vitamin B12"

1

Workinger, Jayme, and Robert Doyle. "14. Vitamin B12 and Drug Development." In Vitamin B12, 338–64. 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742: CRC Press, 2017. http://dx.doi.org/10.1201/9781315119540-15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Bährle-Rapp, Marina. "Vitamin B12." In Springer Lexikon Kosmetik und Körperpflege, 585. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_11068.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Winter, Jerrold. "Vitamin B12." In True Nutrition, True Fitness, 143–54. Totowa, NJ: Humana Press, 1991. http://dx.doi.org/10.1007/978-1-4612-0479-4_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Jomaa, H. "Vitamin B12." In Springer Reference Medizin, 2463–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3262.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Jomaa, Hassan. "Vitamin B12." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_3262-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ball, G. F. M. "Vitamin B12." In Bioavailability and Analysis of Vitamins in Foods, 497–515. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-3414-7_14.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Marks, John. "Vitamin B12." In The Vitamins, 165–69. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-7321-6_26.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Stabler, Sally P. "Vitamin B12." In Present Knowledge in Nutrition, 343–58. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781119946045.ch22.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Drennan, C. L., M. M. Dixon, D. M. Hoover, J. T. Jarrett, C. W. Goulding, R. G. Matthews, and M. L. Ludwig. "Cobalamin-Dependent Methionine Synthase from Escherichia coli: Structure and Reactivity." In Vitamin B12 and B12 -Proteins, 133–55. Weinheim, Germany: Wiley-VCH Verlag GmbH, 2007. http://dx.doi.org/10.1002/9783527612192.ch07.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Evans, Philip R., and Filippo Mancia. "Insights on the Reaction Mechanism of Methyl-malonyl-CoA mutase from the Crystal Structure." In Vitamin B12 and B12 -Proteins, 217–26. Weinheim, Germany: Wiley-VCH Verlag GmbH, 2007. http://dx.doi.org/10.1002/9783527612192.ch13.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Vitamin B12"

1

Dohrn, W., A. Schweers, H. Rietema, M. Lorentschk, and A. Klimkiewicz. "Vitamin B12-Mangel induzierte Panzytopenie als Weaninghindernis." In 63. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1760994.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Abbadi, Mohammad, Sarah Spurgeon, Naziyat Khan, and Martin Warren. "Understanding the Control of a Vitamin B12 Riboswitch." In 2018 UKACC 12th International Conference on Control (CONTROL). IEEE, 2018. http://dx.doi.org/10.1109/control.2018.8516881.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Miller, Nicholas A., and Roseanne J. Sension. "Ultrafast XANES of Excited State Dynamics in Vitamin B12." In Laser Science. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/ls.2016.lf2d.1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Levent, Ayşenur, Yelda Türkmenoğlu, Tuğçe Aksu Uzunhan, Emine Türkkan, and Adem Karbuz. "42 Neurological findings of vitamin B12 deficiency in infancy." In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.42.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Lee, Seoho, Dakota O'Dell, Jessica Hohenstein, Susannah Colt, Saurabh Mehta, and David Erickson. "NutriPhone: vitamin B12 testing on your smartphone (Conference Presentation)." In Optics and Biophotonics in Low-Resource Settings II, edited by David Levitz, Aydogan Ozcan, and David Erickson. SPIE, 2016. http://dx.doi.org/10.1117/12.2210761.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Baurina, A. V. "VITAMIN B12 FERMENTATION PROCESS ON SUNFLOWER PROTEIN ENZYMATIC HYDROLYSATES." In 19th SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings. STEF92 Technology, 2019. http://dx.doi.org/10.5593/sgem2019v/6.3/s08.031.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Zeitouni, O. M., J. A. Perez, M. A. Maravillas, and R. B. Hejal. "Vitamin B12: A Potential Marker for Infection and Sepsis." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3327.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Sianipar, Imelda Rosalyn, Irena Ujianti, Sophie Yolanda, Aditya K. Murthi, Patwa Amani, and Dewi Irawati Soeria Santoso. "Developing vitamin B12 deficient rat model based on duration of restriction diet: Assessment of plasma vitamin B12, homocysteine (Hcy), and blood glucose levels." In SECOND INTERNATIONAL CONFERENCE OF MATHEMATICS (SICME2019). Author(s), 2019. http://dx.doi.org/10.1063/1.5096672.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Shell, Jennifer R., Liberty N. Gendron, Dillon C. Zites, Thomas A. Shell, and Brian W. Pogue. "Light-activated Vitamin B12 Derivatives as Theranostic Agents (Conference Presentation)." In Molecular-Guided Surgery: Molecules, Devices, and Applications V, edited by Brian W. Pogue and Sylvain Gioux. SPIE, 2019. http://dx.doi.org/10.1117/12.2515379.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Zambuzzi, Isadora Melo, Natalia Cristina Bazzo Nahum de Morais, and Nafice Costa Araujo. "VITAMIN B12 DEFICIENCY MIMICKING SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): CASE REPORT." In XL Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2023. http://dx.doi.org/10.47660/cbr.2023.2316.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Vitamin B12"

1

Singh, Ruchi, Akhiya Nail, and Nirendra Kumar Rai. Effectiveness of Vitamin B12 Supplementation on cognitive, motor & mood instability of Parkinson’s disease patients on levodopa treatment :A Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0066.

Full text
Abstract:
Review question / Objective: The treatment of choice for patients of Parkinson's disease is levodopa. However, levodopa has been suggested to decrease Vit B12 level in these patients. Thus, the research question for this systematic review is whether vit B 12 supplementation in Parkinson's disease(PD) patients on treatment with levodopa improves vit B12 level effecting the Cognition, Motor functions and Mood instability among them in comparison to PD patients on levodopa treatment who are not supplemented with Vit B12. Condition being studied: Parkinson disease is the progressive degeneration of dopaminergic neurons present within the substantia nigra that can lead to altered movements along with the prevalence of cognitive and mood instability as a result of dopamine(neurotransmitter) deficiency. The most effective treatment for the Parkinson's disease is the administration of levodopa, a dopamine precursor . Long term treatment with levodopa causes an increase in homocysteine levels and tissue deficiency of vitamin B12 and folate may occur. Vitamin B12 supplementation is administered as after management regime, in Parkinson patient on levodopa treatment . This study aims to conduct a systematic review, of studies , randomized control trials investigating the ability of vitamin B12 supplementation to enhances the recovery/reduce the decline, if any, of the symptoms of cognitive, motor, mood impairments associated with Parkinson's disease patient on levodopa treatment.
APA, Harvard, Vancouver, ISO, and other styles
2

Liu, Yiti, Maoyuan Gou, and Xiaoyan Guo. Features of plasma homocysteine, vitamin B12, and folate in Parkinson’s disease: An updated meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0099.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Lekhanya, Portia Keabetswe, and Kabelo Mokgalaboni. Exploring the effectiveness of vitamin B12 complex and alpha-lipoic acid as a treatment for diabetic neuropathy. Protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0167.

Full text
Abstract:
Review question / Objective: Does Alpha-Lipoic acid increase the uptake of glucose for better glycaemic control? Does vitamin B12 and Alpha-Lipoic acid improve inflammation? The aim of the study is to explore the effectiveness of Vitamin B12 and Alpha-Lipoic Acid as a possible treatment for diabetic neuropathy with major emphasis on markers of inflammation and glucose metabolism. Condition being studied: Diabetic Neuropathy (DN) is a heterogeneous type of nerve damage associated with diabetes mellitus, the condition most often damages nerves in the legs and feet. It presents both clinically and sub-clinically affecting the peripheral nervous system as a result of an increase in glucose concentration which interferes with nerve signalling. After the discovery of insulin as a treatment for Diabetes Mellitus (DM), the prevalence of DN has since increased significantly due to DM patients having a longer life expectancy. It has been estimated that atleast 50% of DM patients will develop DN in their life, with approximately 20% of these patients experiencing neuropathic pain. Nerves are susceptible to changes in glucose concentrations and insulin makes it impossible for neurons to continue regulating glucose uptake.
APA, Harvard, Vancouver, ISO, and other styles
4

Liu, Kefeng, Zhirong Yang, Wang Miao, Bang Zheng, Shanshan Wu, Shuzhang Du, Xiaojian Zhang, Yang Zhao, Shusen Sun, and Jie Zhao. Vitamin B12 levels and risk of all-cause, cardiovascular disease and cancer mortality: a systematic review and dose-response meta-analysis of cohort studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0129.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Rouseff, Russell L., and Michael Naim. Characterization of Unidentified Potent Flavor Changes during Processing and Storage of Orange and Grapefruit Juices. United States Department of Agriculture, September 2002. http://dx.doi.org/10.32747/2002.7585191.bard.

Full text
Abstract:
Citrus juice flavor quality traditionally diminishes after thermal processing and continuously during storage. Our prior studies found that four of the five most potent off-aromas formed during orange juice storage had not been identified. The primary emphasis of this project was to characterize and identify those potent flavor degrading aroma volatiles so that methods to control them could be developed and final flavor quality improved. Our original objectives included: 1 Isolate and characterize the most important unidentified aroma impact compounds formed or lost during pasteurization and storage. 2. Determination of thiamine and carotenoid thermal decomposition and Strecker degradation pathways in model solutions as possible precursors for the unidentified off-flavors. 3. Evaluate the effectiveness of an "electronic nose" to differentiate the headspace aromas of from untreated and heat pasteurized orange and grapefruit juices. 4. Use model systems of citrus juices to investigate the three possible precursor pathways (from 2) for flavor impact compounds formed or lost during pasteurization or storage. RESULTS - The components responsible for citrus storage off flavors and their putative precursors have now been identified. Certain carotenoids (b-carotene) can thermally degrade to produce b-ionone and b-damascenone which are floral and tobacco smelling respectively. Our GC-O and sensory experiments indicated that b-damascenone is a potential storage off-flavor in orange juice. Thiamine (Vitamin B1) degradation produces 2-methyl-3-furan thiol, MFT, and its dimer bis(2- methyl-3-furyl) disulfide which both produce meaty, savory aromas. GC-O and sensory studies indicated that MFT is another storage off-flavor. Methional (potato aroma) is another off flavor produced primarily from the reaction of the native amino acid, methionine, and oxidized ascorbic acid (vitamin C). This is a newly discovered pathway for the production of methional and is more dominant in juices than the classic Maillard reaction. These newly identified off flavors diminish the flavor quality of citrus juices as they distort the flavor balance and introduce non-typical aromas to the juice flavor profile. In addition, we have demonstrated that some of the poor flavor quality citrus juice found in the market place is not only from the production of these and other off flavors but also due to the absence of desirable flavor components including several potent aldehydes and a few esters. The absence of these compounds appears to be due to incomplete flavor volatile restoration after the making of juice concentrates. We are the first to demonstrate that not all flavor volatiles are removed along with water in the production of juice concentrate. In the case of grapefruit juice we have documented which flavor volatiles are completely removed, which are partially removed and which actually increase because of the thermal process. Since more that half of all citrus juices is made into concentrate, this information will allow producers to more accurately restore the original flavor components and produce a juice with a more natural flavor. IMPLICATIONS - We have shown that the aroma of citrus juices is controlled by only 1-2% of the total volatiles. The vast majority of other volatiles have little to no direct aroma activity. The critical volatiles have now been identified. The ability to produce high quality citrus juices requires that manufacturers know which chemical components control aroma and flavor. In addition to identifying the critical flavor components (both positive and negative), we have also identified several precursors. The behavior of these key aroma compounds and their precursors during common manufacturing and storage conditions has been documented so manufacturers in Israel and the US can alter production practices to minimize the negative ones and maximize the positive ones.
APA, Harvard, Vancouver, ISO, and other styles
6

Depressed young people have lower vitamin B12 and vitamin D levels than their peers. ACAMH, August 2020. http://dx.doi.org/10.13056/acamh.12905.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Vitamin B12' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography