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Academic literature on the topic 'Virus de la dengue – La Réunion (France ; île)'
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Journal articles on the topic "Virus de la dengue – La Réunion (France ; île)"
Bohers, Chloé, Marie Vazeille, Lydia Bernaoui, Luidji Pascalin, Kevin Meignan, Laurence Mousson, Georges Jakerian, Anaïs Karch, Xavier de Lamballerie, and Anna-Bella Failloux. "Aedes albopictus is a competent vector of five arboviruses affecting human health, greater Paris, France, 2023." Eurosurveillance 29, no. 20 (May 16, 2024). http://dx.doi.org/10.2807/1560-7917.es.2024.29.20.2400271.
Full textKlitting, Raphaëlle, Géraldine Piorkowski, Dominique Rousset, André Cabié, Etienne Frumence, Alisé Lagrave, Anne Lavergne, et al. "Molecular epidemiology identifies the expansion of the DENV2 epidemic lineage from the French Caribbean Islands to French Guiana and mainland France, 2023 to 2024." Eurosurveillance 29, no. 13 (March 28, 2024). http://dx.doi.org/10.2807/1560-7917.es.2024.29.13.2400123.
Full textVilain, Pascal, Muriel Vincent, Anne Fouillet, Katia Mougin-Damour, Xavier Combes, Adrien Vague, Fabien Vaniet, Laurent Filleul, and Luce Menudier. "Flexibility of ED surveillance system to monitor dengue outbreak in Reunion Island." Online Journal of Public Health Informatics 11, no. 1 (May 30, 2019). http://dx.doi.org/10.5210/ojphi.v11i1.9872.
Full textDissertations / Theses on the topic "Virus de la dengue – La Réunion (France ; île)"
Hafsia, Sarah. "Transmission des virus de la dengue de La Réunion par les moustiques Aedes albopictus de La Réunion et d'autres îles du Sud-Ouest de l'océan Indien : rester au plus proche du terrain pour une meilleure compréhension de ces interactions." Electronic Thesis or Diss., La Réunion, 2024. http://www.theses.fr/2024LARE0009.
Full textDengue is the most widespread arbovirosis worldwide, with half the world's population living in at-risk areas, mainly in the tropical and subtropical belt. Dengue virus (DENV), the etiological agent of this disease, is an Orthoflavivirus with four different serotypes (DENV-1 to DENV-4). Two species of mosquito, Aedes aegypti and Aedes albopictus, are the main vectors involved in transmitting DENV to human populations worldwide. Since 2017, Reunion Island, a French overseas department located in the South-West Indian Ocean (SWIO), has been facing an unprecedented dengue epidemic characterized by a significant increase in the number of human cases and severe forms of the disease. As the Ae. albopictus mosquito is recognized as the vector species of DENV in human populations on Reunion Island, the main objective of this thesis was to study the interactions between DENV and Ae. albopictus populations on Reunion Island, in order to better understand the role of this vector in dengue epidemiology. In the first part of this thesis, we retraced the history of dengue fever in the SWIO, and more specifically in Reunion Island. We then characterized the genetic diversity of DENV-1 and DENV-2 viral strains circulating in Reunion Island and the Seychelles during recent epidemics. The third part of this thesis was devoted to analyzing the vectorial competence (ability of a mosquito population to transmit a given pathogen) of Ae. albopictus populations of different generations (F0 and F2 generations) collected in different locations around the island. We also examined the influence of the Wolbachia intracellular bacteria on vector competence phenotypes. Finally, we studied the vectorial competence of Ae. aegypti and Ae. albopictus populations from different SWIO islands infected with dengue, Chikungunya and Zika viruses. The results of this work provide a better understanding of the epidemiology of dengue and the transmission dynamics of arboviruses in the SWIO islands, particularly on Reunion Island
Barbar, Tatiana. "Exploring extrinsic and biological factors shaping Aedes albopictus vector competence : Assessing the role of Wolbachia in intestinal homeostasis maintenance." Electronic Thesis or Diss., La Réunion, 2024. http://www.theses.fr/2024LARE0004.
Full textArboviruses (Arthropod-Borne Viruses), specifically those belonging to the Flaviviruses genus, including Dengue virus, Zika virus, Japanese Encephalitis Virus, and others, pose significant threats to public health. These emerging infectious diseases put millions at risk of infection, causing thousands of deaths worldwide, each year. Tropical and subtropical regions have been highly susceptible to these viruses due to a combination of several factors, including conductive humid climate, rich natural biodiversity, abundant breeding sites, rapid urbanization, increased globalization, extensive travel, as well as limited resources for vector control. Dengue is considered one of the fastest and most dangerous tropical fever diseases transmitted to humans by mosquitoes. Due to its widespread occurrence and high morbidity and mortality rates, it is identified as the leading cause of fever after Malaria. La Réunion Island, a French department located in the Southwest of the Indian Ocean, has been significantly impacted by the emergence and re-emergence of dengue epidemics since 1977. Since then, this has been considered a major health problem as it has caused thousands of infections and hundreds of fatalities. These epidemics were triggered by the primary mosquito vector for Dengue virus on the island, Aedes albopictus, one of the most invasive mosquito species. Based on specific environmental and biological factors, mosquito populations in La Réunion had developed a susceptibility to the infection by the four-dengue virus (DENV) serotypes, contributing to high transmission efficiency and creating a complex interplay between environmental and biological factors. Thus, understanding the biology of Aedes albopictus competence towards the DENV serotypes circulating locally is crucial for devising effective strategies to mitigate Dengue transmission in La Réunion. As of today, no medically confirmed treatment has been established for Dengue virus. Thus, vector control, limiting the density of vector mosquitoes is the most usedMy thesis aims to explore both extrinsic and intrinsic factors influencing the competence of Aedes albopictus towards the Dengue virus serotypes that have emerged in La Réunion during the last epidemics. Special focus will be addressed on understanding the mutualistic relationship between Aedes albopictus and the Wolbachia bacterium, and its impact on maintaining intestinal homeostasis both under normal conditions and following DENV ingestion of a blood meal and the Dengue virus
Clain, Marie Élodie. "Valorisation des éco-extraits de plantes médicinales réunionnaises dans la lutte contre les maladies virales émergentes de l'océan Indien." Thesis, La Réunion, 2018. http://www.theses.fr/2018LARE0033/document.
Full textEmerging and re-emerging vector-borne viral diseases such as dengue, chikungunya or zika are responsible for many severe epidemics worldwide. Recently, the rapid spread of zika virus (ZIKV) worldwide and the serious neurological complications associated with ZIKV infection have prompted the World Health Organization (WHO) to declare ZIKV a public health emergency. Today, preventive or curative measures against ZIKV infection are almost non-existing. On the other hand, the endemic flora of Reunion Island is known as a rich, renewable and promising source of natural anti-infective products. The registration of 19 medicinal plants from Reunion Island in the French pharmacopoeia highlights the therapeutic potential of natural substances derived from local biodiversity. The work was dedicated to the identification of natural anti-ZIKV substances from a selection of seven medicinal plants from La Reunion registered in the French pharmacopoeia. In a first step, in collaboration with a local start-up (Bourbon Extracts), a solvent-free microwave-assisted extraction was applied to the seven selected plants in order to obtain eco-extracts. In a second step, the screening for antiviral activity, using a ZIKV molecular clone with a reporter gene, allowed the identification of two candidate plants: Aphloia theiformis and Psiloxylon mauritianum. After verifying the absence of cytotoxicity and genotoxicity of the active extracts, the antiviral activity was also demonstrated on other types of extracts using traditional extraction methods (infusion, decoction and maceration). The antiviral activity has been validated on different strains of ZIKV (historical and epidemic) as well as on the four serotypes of the dengue virus. Finally, the mode of action of the two active extracts has been studied. It has been shown that the eco-extracts from A. theiformis and P. mauritianum target the early steps of the viral cycle by inhibiting the attachment of the virus to the host cell. Using electron microscopy, it has been shown that the eco-extract of A. theiformis deforms the viral particle preventing its attachment to the membrane of the host cell. These results demonstrate the importance of medicinal plants from Reunion Island as a source of natural anti-infectious substances
Fouillaud, Mireille. "Micro-organismes et virus associés au nid de la guêpe Polistes hebraeus F. (Hymenoptera Vespidae) à l'Île de la Réunion." Aix-Marseille 1, 1994. http://www.theses.fr/1994AIX11045.
Full textReynaud, Bernard. "Transmission des virus de la striure, du stripe et de la mosai͏̈que du mai͏̈s par leurs vecteurs Cicadulina Mbila (Naude, 1924) et Peregrinus maidis (Ashmead, 1890) (Homoptera) : approches biologique, génétique et épidémiologique de la relation vecteur-virus-plante." Montpellier 2, 1988. http://www.theses.fr/1988MON20223.
Full textClaverie, Sohini. "Étude de la diversité et de la structure des communautés virales à l’échelle des agro-écosystèmes. Le modèle épidémiologique des mastrévirus des Poaceae à La Réunion." Thesis, La Réunion, 2020. http://www.theses.fr/2020LARE0011.
Full textViruses’ ubiquity, abundance and diversity have highlighted that they are naturally embedded into global ecosystems. In order to better understand how they interact, adapt and evolve, it is essential to study them at the ecosystem scale, particularly at the agro-ecosystem scale where the promiscuity between wild and cultivated ecosystems facilitates new interactions favouring the emergence of new viral variants. This study focused on phytoviruses of the genus Mastrevirus, transmitted by leafhoppers and responsible for many crop diseases in Africa and the Indian Ocean islands. Our work focused on the development of a metagenomic approach called RCA-RA-NGS targeting viruses with small circular DNA genomes. This approach is based on rolling-circle amplification step followed with amplicons tagging using random PCR allowing multiplexing of up to 1200 samples and Illumina high-throughput sequencing before classification of the reads obtained by similarity search and phylogenetic placement. The analysis of nearly 3000 samples representing 30 species of Poaceae showed that 18 of these species and globally 8% of the evaluated plants were infected by masteviruses. In addition to the discovery of previously undescribed mastrevirus species, our results provide a comprehensive view of the network of mastrevirus-host association within an agro-ecosystem. The topology of this network suggests (1) no modularity and only nestedness of specialists host ranges with those of generalists, (2) hosts acting as viral hub and (3) the presence of recombination
Rassaby, Laurence. "Le syndrome de la feuille jaune de la canne à sucre causé par le Sugarcane yellow leaf virus (SCYLV) à la Réunion : caractérisation et impact." La Réunion, 2001. http://elgebar.univ-reunion.fr/login?url=http://thesesenligne.univ.run/01_15_Rassaby.pdf.
Full textTecher, Sophie. "Criblage d’activités biologiques de plantes endémiques ou indigènes de La Réunion - Recherche de molécules antivirales ciblant le virus du chikungunya." Thesis, La Réunion, 2013. http://www.theses.fr/2013LARE0014/document.
Full textThe aims of this PhD work were to identify plants and/or molecules with cytotoxic, antioxidant, anti-inflammatory or antiviral (chikungunya virus , CHIKV) activities in order to find therapeutic alternatives towards oxidative stress and inflammation, mechanisms involved in chronic noncommunicable diseases (diabetes, obesity ...), and chikungunya disease, reemerging vector-borne disease. The first part of this work presents the results obtained from a biological screening carried out on a selection of eighteen endemic and indigenous plants of La Réunion. The targeted activities were cytotoxicity on a human cell line (THP-1), antioxidant activities evaluated using an in cellulo hemolysis assay and four chemical tests (TEAC / DPPH / FRAP / ORAC) together with an evaluation of the content of phenolic compounds (FOLIN test) and anti-inflammatory activity tested in murine macrophages (RAW cells-BlueTM). The results allowed to highlight activities of different extracts in particular : cytotoxic for Carissa spinarum, antioxidant for Dryopteris wallichiana and Agarista buxifolia and anti-inflammatory for Stillingia lineata and Indigofera ammoxylum.The second part of this work is devoted to the phytochemical study of Stillingia lineata, an indigenous species of La Réunion chosen because of the results obtained in this preliminary biological screening and those carried out in Phytochik programme. Bioassay-guided fractionation performed on Vero cells (green monkey kidney cells Cercopithecus aethiops) infected with CHIKV led to the isolation of three rare macrocycle-type diterpenes called tonantzitlolone and a new pimarane. The 4'-acetoxytonantzitlolone was identified as a candidate molecule against CHIKV (EC50 = 7 μM). Structure-activity relationships have been defined, the presence of an oxygenated group on the side chain of tonantzitlolones seems to play an important role in the antiviral response of the diterpene skeleton