Dissertations / Theses on the topic 'Viral disease'
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Gangadharan, Bevin. "Proteomics in viral disease." Thesis, University of Oxford, 2006. http://ora.ox.ac.uk/objects/uuid:c66c53ed-a824-4f99-8f2b-d2bc65a984c7.
Full textFleeton, Marina N. "Genetic vaccination against acute viral disease /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3811-3/.
Full textLeo, Nancy Stefany. "Viral Antibodies and Immunoregulation in Autoimmune Disease." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/271610.
Full textQuinlivan, Mark Lee. "Viral genetic variation in varicella zoster virus disease." Thesis, Queen Mary, University of London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418302.
Full textStoppelkamp, Sandra. "New viral and transgenic models of Alzheimer's disease." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=136906.
Full textAgarwal, Kaushik. "Immunogenetic studies in autoimmune and viral liver disease." Thesis, University of Newcastle upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275585.
Full textSilverstein, Noah J. "Disease Tolerance, Epigenetic Inheritance, and Surviving Pathogenic Viral Infections." eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1149.
Full textDovigi, Allan Webster-Cyriaque Jennifer. "HIV salivary gland disease a role for viral infection /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2005. http://dc.lib.unc.edu/u?/etd,297.
Full textTitle from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Master of Science in the Department of Oral and Maxillofacial Pathology School of Dentistry." Discipline: Oral and Maxillofacial Pathology; Department/School: Dentistry.
Nitsovych, I. R. "Treatment of polyhydramnios caused by acute respiratory viral disease." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18719.
Full textMoody, Adrian John. "Mapping genetic resistance to infectious bursal disease." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326754.
Full textZaid, Ali, and n/a. "IMMUNE EVASION AND DISEASE MECHANISMS IN ROSS RIVER VIRUS INFECTION." University of Canberra. Biomedical Sciences, 2008. http://erl.canberra.edu.au./public/adt-AUC20091216.122508.
Full textLarsson, Anna-Karin. "Early life cytokines, viral infections and IgE-mediated allergic disease." Doctoral thesis, Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm university, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1224.
Full textRibeiro, Ruy Miguel. "Models of viral diversity and disease development in HIV infection." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302403.
Full textMcManus, T. E. "Viral infection and associated inflammation in chronic obstructive pulmonary disease." Thesis, Queen's University Belfast, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426766.
Full textTüre, Olcay. "Studies on the viral proteins of infectious bursal disease viruses /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487757723997915.
Full textWark, Kim Louise. "Expression and processing of infectious bursal disease virus proteins." Thesis, University of Hertfordshire, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323651.
Full textAshraf, Shamaila. "Studies on infectious bursal disease virus." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1124124381.
Full textTitle from first page of PDF file. Document formatted into pages; contains xvi, 216 p.; also includes graphics (some col.). Includes bibliographical references (p. 180-216). Available online via OhioLINK's ETD Center
Zhang, Xu-Sheng. "Mathematical models of plant disease epidemics that involve virus interactions." Thesis, University of Greenwich, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327341.
Full textMillar, N. S. "Molecular cloning and sequence analysis of Newcastle disease virus." Thesis, University of Newcastle Upon Tyne, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380750.
Full textFrisan, Teresa. "Mechanisms of immune escape in EBV associated malignancies : Hodgkin's disease and Burkitt's lymphoma /." Stockholm : Karolinska institutet, 1999. http://diss.kib.ki.se/1999/91-628-3660-9/.
Full textYip, Chi-wai. "Characterization of cellular receptors of infectious bursal disease virus in chickens." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B36759533.
Full textWikramaratna, Paul Silva. "The evolution of viral diversity." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:1d718b15-af79-4567-84ef-f97f61f75369.
Full textDalmau, Moreno Judith. "Viral and host factors involved in rapid HIV-1 disease progression." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/133268.
Full textRemarkable variation in clinical outcome can be observed following HIV-1 infection. While some HIV-1–infected individuals are able to suppress viral replication to very low levels (<2000 copies/mL) and/or maintain high CD4+ T-cell counts over many years without antiretroviral therapy (HIV controllers), others quickly progress to AIDS or meet the current criteria for antiretroviral treatment within the first 3 years after primary infection (rapid progressors, RP). Furthermore, a minority of highly viremic individuals remain asymptomatic with high CD4+ T-cell counts (viremic non-progressors, VNP), similar to those observed in the non-progressive disease model of SIV infection in natural hosts. The study of extreme phenotypes can provide important information on the interactions established between the viral variant and the host during primary HIV infection and the subsequent clinical evolution of the infection. Indeed, the study of HIV controllers (including elite controllers, who maintain plasma viral RNA under detectable levels [<50 copies/mL]) is providing relevant data on HIV immunopathogenesis. The other extreme comprises RPs, who account for a relatively small percentage of the HIV-1-infected population. Nevertheless, the implications of their immunogenetic and immunopathogenic characteristics are remarkable. This thesis originates from the comprehensive study of 2 cases of extremely severe rapid progression that was later extended to the recruitment and study of an unprecedentedly large and well-defined cohort of RPs. The specific objective was to investigate a wide range of viral and host factors involved in rapid progression of HIV-1 infection, in contrast to other phenotypes, namely, individuals with an average progression profile (standard progressors, SP) and VNPs. The results of this study demonstrate convergence of the viral and host factors contributing to the clinical severity of rapid progression. Individuals infected with highly replicative, dual-tropic, HLA-adapted viruses were shown to be more prone to develop AIDS-defining symptoms during primary HIV-1 infection, since in many cases they are also unable to mount humoral and cellular HIV-1-specific immune responses. Concordant HLA supertypes between the source and the recipient, the presence of common and risk HLA class I alleles, and the low frequency of protective HLA alleles were also shown to further accelerate disease progression. In addition, transcriptome analysis Revealed that RPs have a specific CD4+ and CD8+ T-cell transcriptome profile similar to that observed in pathogenic SIV-infected rhesus macaques and characterized by higher expression of interferon-stimulated genes. VNPs, on the other hand, were characterized by a gene regulation profile similar to that of non-pathogenic SIV-infected sooty mangabeys. The present study provides important insights into the host and viral traits driving progression of HIV-1 infection, which have relevant implications for our knowledge of HIV pathogenesis and the importance of early monitoring of disease course.
Axdorph, Ulla. "Clinical and immunopathological studies in Hodgkin's disease with special reference to prognosis /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4442-3/.
Full textRamaley, Patricia A. "Host genetics of HIV-1 infection and disease progression in Uganda." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365714.
Full textCarlsson, Beatrice. "Human Caliciviruses: a study of viral evolution, host genetics and disease susceptibility." Doctoral thesis, Linköpings universitet, Molekylär virologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76036.
Full textChoudhury, Sourav Roy. "Developing an Adeno-Associated Viral Vector (AAV) Toolbox for CNS Gene Therapy: A Dissertation." eScholarship@UMMS, 2001. http://escholarship.umassmed.edu/gsbs_diss/809.
Full textChoudhury, Sourav Roy. "Developing an Adeno-Associated Viral Vector (AAV) Toolbox for CNS Gene Therapy: A Dissertation." eScholarship@UMMS, 2016. https://escholarship.umassmed.edu/gsbs_diss/809.
Full textPeacey, Matthew, and n/a. "Creation and investigation of a versatile Rabbit haemorrhagic disease virus-like particle vaccine." University of Otago. Department of Microbiology & Immunology, 2008. http://adt.otago.ac.nz./public/adt-NZDU20080215.155033.
Full textKapulu, Melissa Chola. "Pre-clinical development of viral vectored transmission-blocking malaria vaccines." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:a5610025-28e1-433f-9487-aaa1f6d641a0.
Full textRudd, Matthew Francis, and mikewood@deakin edu au. "Virulence determinants of infectious bursal disease virus." Deakin University. School of Biological and Chemical Sciences, 2003. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20050825.103742.
Full textThomas, Claire Philippa. "The expression of bluetongue virus non-structural protein NS2 and its structure-function relationship." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292328.
Full textWythe, Sarah Elizabeth. "The role of dendritic cells in a polarised model of viral pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502909.
Full textPrendergast, Andrew John. "Immunological and viral influences on HIV-1 disease progression in children and adults." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526101.
Full textYip, Chi-wai, and 葉志偉. "Characterization of cellular receptors of infectious bursal disease virus in chickens." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B36759533.
Full textMCCOMBIE, SUSAN CAROLE. "CULTURAL FACTORS RELATED TO THE EPIDEMIOLOGY OF VIRAL HEPATITIS IN A SOUTHWESTERN UNITED STATES COUNTY (INFECTIOUS DISEASE, SOCIOECONOMIC, PUBLIC HEALTH, BEHAVIOR, COMMUNICABLE)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/188152.
Full textWong, Hiu-ling Beatrice. "Development of antibody and antigen detection assays and vaccines for SARS associated coronavirus." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B39634024.
Full textWong, Hiu-ling Beatrice, and 黃曉靈. "Development of antibody and antigen detection assays and vaccines for SARS associated coronavirus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39634024.
Full textStåhl, Karl. "Bovine viral diarrhoea virus and other reproductive pathogens : epidemiological studies in Peruvian cattle /." Uppsala : Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200653.pdf.
Full textTanov, Emil Pavlov. "The identification of biologically important secondary structures in disease-causing RNA viruses." University of the Western Cape, 2012. http://hdl.handle.net/11394/4562.
Full textViral genomes consist of either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA). The viral RNA molecules are responsible for two functions, firstly, their sequences contain the genetic code, which encodes the viral proteins, and secondly, they may form structural elements important in the regulation of the viral life-cycle. Using a host of computational and bioinformatics techniques we investigated how predicted secondary structure may influence the evolutionary dynamics of a group of single-stranded RNA viruses from the Picornaviridae family. We detected significant and marginally significant correlations between regions predicted to be structured and synonymous substitution constraints in these regions, suggesting that selection may be acting on those sites to maintain the integrity of certain structures. Additionally, coevolution analysis showed that nucleotides predicted to be base paired, tended to co-evolve with one another in a complimentary fashion in four out of the eleven species examined. Our analyses were then focused on individual structural elements within the genome-wide predicted structures. We ranked the predicted secondary structural elements according to their degree of evolutionary conservation, their associated synonymous substitution rates and the degree to which nucleotides predicted to be base paired coevolved with one another. Top ranking structures coincided with well characterized secondary structures that have been previously described in the literature. We also assessed the impact that genomic secondary structures had on the recombinational dynamics of picornavirus genomes, observing a strong tendency for recombination breakpoints to occur in non-coding regions. However, convincing evidence for the association between the distribution of predicted RNA structural elements and breakpoint clustering was not detected.
Biswas, Sumi. "Prime boost vaccination with viral vectors targeting apical membrane antigen 1." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:a17ab4e4-9b81-4ab3-b02f-41d9da36c6ab.
Full textHsu, Pao-Chu. "Prenatal Stress, Depression, and Herpes Viral Titers." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4818.
Full textLasecka, Lidia. "Studies on the replication of Nairobi sheep disease virus in cultured cells." Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618322.
Full textNavér, Lars. "Perinatal HIV-1 infection : aspects on clinical presentation, viral dynamics and epidemiology /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-983-8/.
Full textBollyky, Paul Laszlo. "Viral genetic diversity and clinical disease in Hepatitis B virus infection : a phylogenetic approach." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301179.
Full textMcMillan, Kirsty Jane. "Development and characterisation of viral vectors to study the molecular mechanisms of Parkinson's disease." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.654440.
Full textMiller, Pamela S. "The relationship between exhaustion, viral pathogenesis, and immuno-inflammatory activation in coronary artery disease." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1872114411&sid=11&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Full textSinganayagam, Aran. "Effect of inhaled corticosteroids on viral and bacterial infection in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/24469.
Full textYeung, Yin-shan. "Molecular characterization of apoptosis induced by severe acute respiratory syndrome coronavirus spike protein." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B38302366.
Full textBartley, Lucy Margaret Antonia. "The transmission dynamics of dengue infections." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343215.
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