Relevant bibliographies by topics / Veterinary Toxicology and Pharmacology

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Veterinary Toxicology and Pharmacology'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

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Journal articles on the topic "Veterinary Toxicology and Pharmacology"

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Bywater, R. J. "Comparative veterinary pharmacology, toxicology & therapy." British Veterinary Journal 143, no. 5 (September 1987): 482. http://dx.doi.org/10.1016/0007-1935(87)90029-7.

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FINK, J. "EUROPEAN ASSOCIATION FOR VETERINARY PHARMACOLOGY AND TOXICOLOGY." Journal of Veterinary Pharmacology and Therapeutics 9, no. 1 (March 1986): 116–17. http://dx.doi.org/10.1111/j.1365-2885.1986.tb00021.x.

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Kobal, Silvestra, and Vitomir Cupic. "Importance of the evaluation of drugs used in veterinary medicine." Veterinarski glasnik 61, no. 5-6 (2007): 325–35. http://dx.doi.org/10.2298/vetgl0706325k.

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The use of veterinary medicines in Slovenia is regulated by the Medicinal Products Act, by the Veterinary Practice Act, other legislative acts and some administrative acts. Supervision and coordination over pre-clinical and clinical evaluation is preformed by the Laboratory of Pharmacology and Toxicology which is a part of the Unit for Laboratory and Clinical Testing of Drugs at the National Veterinary Institute, on the basic of the concession. The Laboratory of Pharmacology and Toxicology to cooperate with the clinics and institutes of the Veterinary Faculty in Ljubljana.
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Leaver, David. "Veterinary toxicology in Australia." Trends in Pharmacological Sciences 8, no. 7 (July 1987): 262–65. http://dx.doi.org/10.1016/0165-6147(87)90199-4.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 82, no. 2 (March 1, 1999): 454. http://dx.doi.org/10.1093/jaoac/82.2.454.

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Ross, Frank P. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 75, no. 1 (January 1, 1992): 141–42. http://dx.doi.org/10.1093/jaoac/75.1.141.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 76, no. 1 (January 1, 1993): 165–67. http://dx.doi.org/10.1093/jaoac/76.1.165a.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 77, no. 1 (January 1, 1994): 199–201. http://dx.doi.org/10.1093/jaoac/77.1.199.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 78, no. 1 (January 1, 1995): 194–95. http://dx.doi.org/10.1093/jaoac/78.1.194.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 79, no. 1 (January 1, 1996): 269–70. http://dx.doi.org/10.1093/jaoac/79.1.269.

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Dissertations / Theses on the topic "Veterinary Toxicology and Pharmacology"

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Rawal, Sumit. "Mechanisms of the Extreme Sensitivity of Turkeys to Aflatoxin B1." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/568.

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The pathogenesis of hepatotoxic and hepatocarcinogenic actions of the mycotoxin aflatoxin B1 (AFB1) involves initial bioactivation by microsomal cytochrome P450s (P450) to a reactive and electrophilic intermediate, exo-aflatoxin B1-8,9-epoxide (exo-AFBO). Poultry, especially turkeys, are extremely sensitive to AFB1, a condition associated with efficient epoxidation by P450s. The purpose of this research was to 1) discover and characterize the P450s in turkey liver responsible for AFB1 bioactivation, and 2) determine the relative importance of these P450s in turkey liver. Initial investigations led to the discovery of CYP1A5. We then identified CYP3A37, a human CYP3A4 homologue from turkey liver, which along with CYP1A5 plays an important role in the bioactivation of AFB1 to exo-AFBO. The E. coli-expressed CYP3A37 possessed striking similarities to human CYP3A4, in terms of its catalytic activities and the kinetics of AFB1 oxidation. After the discovery of CYP3A37, further research evaluated its relative importance to CYP1A5, with respect to the epoxidation of AFB1, to determine which of the homologues bioactivated relatively low "real world" AFB1 concentrations, reflective of the potential dietary exposure. Using antibodies directed to both the enzymes as tools in immuno-inhibition experiments, we determined that CYP1A5 contributes to about 98% of the exo-AFBO formation at the low AFB1 concentrations (0.1 µM), which led us to conclude that CYP1A5 is likely the dominant homologue involved in the extreme sensitivity of the turkeys to AFB1. CYP3A37 also efficiently epoxidated AFB1, but only at high concentrations of this mycotoxin, not likely to be achievable in turkey liver in vivo. Our research has helped shed light on the relative importance of CYP1A5 and CYP3A37 in the bioactivation of AFB1 to the toxic exo-AFBO, and thus on the mechanisms of the extreme sensitivity of turkeys to AFB1. Given that AFB1 is a ubiquitous component of corn-based poultry feed and contamination is practically unavoidable, we conducted further studies evaluating the chemopreventive action of probiotic bacteria, Lactobacillus, on AFB1 toxicity in turkeys. Probiotic bacteria are known to bind AFB1, thus reducing its bioavailability. A mix of probiotic bacteria provided protection against key endpoints of aflatoxicosis, like AFB1-induced reduction in body and liver weights. Our data demonstrate that Lactobacillus was protective against aflatoxicosis in turkeys, thus validating its use as a possible chemopreventive, thereby helping alleviate the significant annual losses to the poultry industry due to feed contamination by AFB1.
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Thomas, Sarah Elizabeth. "A Prevalence Study of Southeast Origin Sale Barn Beef Cattle, Comingled in Warren County, Kentucky, Persistently Infected with Bovine Viral Diarrhea Virus, including the Effects of Season and Body Weight." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1070.

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Bovine viral diarrhea (BVD) is an economically important disease of cattle. Calves persistently infected (PI) with the bovine viral diarrhea virus (BVDV) are a powerful agent for spread of the virus. A total of 24,423 southeast origin beef cattle comingled at three Warren County, Kentucky locations were tested from November 2007 to June 2010 for PI BVDV. A total of 97 head tested positive for PI BVDV, giving an average overall prevalence of 0.397%. Calves tested were subdivided into categories for additional calculations of dependence. A total of 8,910 were categorized by weight range upon testing (300-399 lbs, 400-499 lbs, 500-599 lbs, and 600-699 lbs). Prevalence does show a dependence on weight, with a higher prevalence found in lower weight classes, especially 300-399 lb calves (P<0.001). A total of 24,423 were categorized by season at time of testing (Fall, Winter, Spring, Summer). Prevalence does not show a dependence on season (P>0.05). Although eradication programs are not likely to be organized in the United States, several control programs have been developed. These findings can be used as additional support for PI testing of calves, especially those in lighter weight classes, as part of a BVD control program.
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Monteiro, Davolli Gabriel. "REVERSIBLE DOWNREGULATION OF HYPOTHALAMIC-PITUITARY-GONADAL AXIS IN THE STALLION WITH A THIRD-GENERATION GNRH ANTAGONIST." UKnowledge, 2015. http://uknowledge.uky.edu/gluck_etds/22.

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The objectives of this thesis were: (1) to evaluate the downregulation of the stallion hypothalamic-pituitary-gonadal (HPG) axis by a GnRH antagonist (acyline) based upon endocrine, seminal, testicular and behavioral effects, and (2) to assess recovery after treatment. Stallions were treated for 50 days (n=4; 330µg/kg acyline q 5d) and controls (n=4) received vehicle alone. Stallions were assessed pre-treatment and for 72 days after last treatment. Treatment induced declines (p<0.05) in FSH, LH, testosterone (to castrate levels) and estrone sulfate. Gonadotropins and testosterone returned to control values within nine days and estrone sulfate by 14 days after treatment discontinuation. Acyline-treated stallions failed to respond with FSH, LH and testosterone increase after exogenous GnRH stimulation (25µg gonadorelin, IV) compared to pre-treatment and control stimulation. Total sperm numbers and motility were reduced in acyline-treated stallions, as well as total seminal plasma protein and testicular volume (p<0.05). Time to ejaculation was increased in acyline group (p<0.5). Testicular, sexual behavior and most seminal parameters regained normal levels within 72 days after treatment ceased. Sperm output of acyline-treated stallions was regained within seven months after ending treatment. Acyline reversibly suppressed the stallion HPG axis, thus has potential for treating the androgen-dependent Equine-Arteritis-Virus carrier state and as behavior modulator.
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Zhu, Wenying. "GLUCOCORTICOID-INDUCED CHONDROCYTE CYTOTOXICITY AT DOSES RECOMMENDED FOR INTRA-ARTICULAR THERAPY IN HORSES." UKnowledge, 2015. http://uknowledge.uky.edu/gluck_etds/23.

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Intra-articular glucocorticoid injections are commonly used to treat synovitis and osteoarthritis in horses. These agents are highly effective at relieving pain, swelling, and other symptoms of joint inflammation. The drugs also have therapeutic benefits by down regulating the expression of cytokines and protease enzymes that participate in the degradation of articular cartilage. However, detrimental effects on chondrocyte function and cell viability that is independent of osteoarthritis pathogenesis have been described and linked to glucocorticoid use. These side effects are both drug- and dose-dependent. This study tested the hypothesis that manufacture recommended dosage levels of methylprednisolone, betamethasone, and triamcinolone that are widely used in equine clinical practice are cytotoxic to articular chondrocytes. Drug-induced chondrocyte cytotoxicity was evaluated in monolayer cultures, cartilage explants, and equine fetlock joints. Total RNA was isolated from control and IL-1β stimulated primary chondrocytes and synoviocytes in culture. Changes in steady state mRNA for targeted gene transcripts related to inflammation and normal cell function were measured using reverse transcription and quantitative PCR. Inducible nitric oxide synthase activity was evaluated using nitrite production. Drug-induced chondrocyte cytotoxicity occurred at drug dosage levels frequently used in equine clinical practice. Both drug- and dose-dependent effects on chondrocyte and synoviocyte gene expression were observed. Maximum anti-inflammatory activities for the glucocorticoids were observed at in vitro concentrations below manufacturer-recommended levels. Results from this study suggest that lower glucocorticoid dose ranges for intra-articular therapy in horses should be validated to maximize the ratio of their therapeutically beneficial anti-inflammatory efficacy against detrimental effects on cell function and viability.
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Taylor, Victoria A. "PHYSIOLOGICAL CHANGES ASSOCIATED WITH PREGNANT OR NONPREGNANT MARES GRAZING PASTURES OF ORCHARDGRASS-BLUEGRASS, KENTUCKY 31 TALL FESCUE INFECTED WITH EPICHLOË COENOPHIALA, OR KYFA9821 TALL FESCUE INFECTED WITH THE NOVEL ENDOPHYTE AR584." UKnowledge, 2017. https://uknowledge.uky.edu/gluck_etds/33.

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Kentucky 31 tall fescue (KY31) infected with the common toxic endophyte strains of Epichloё coenophiala produces toxic alkaloids that improve plant vigor, but cause numerous adverse effects in grazing animals. Researchers developed a variety of KY31 containing an alternative strain of E. coenophiala, termed novel endophyte (NE). Adverse health effects in mares have not been evaluated. Experiments in this thesis tested the hypothesis that the NE pasture does not cause adverse effects typically associated with KY31. Specific aims were to: 1) compare forage ergovaline concentrations between KY31 vs NE pastures; 2) evaluate palmar artery diameters in mares grazing KY31, NE, or orchardgrass-bluegrass (OGBG) pastures; 3) determine mare serum prolactin, estradiol, and progesterone concentrations associated with ingesting each pasture type over time; and 4) measure foaling outcomes, including percentage of live foals, foal birth weights, and foal growth rates. In 2015, six nonpregnant mares grazed KY31, six pregnant mares grazed NE and six pregnant mares grazed OGBG pastures. In 2016, eighteen mares were used; six mares grazed each pasture type. Study results showed that ergovaline did not appear to be produced by NE. Novel endophyte pasture did not have negative effects on palmar artery diameter, reproductive hormones, or foaling outcomes.
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Sargeant, Aaron Matthew. "Preclinical Efficacy and Safety Evaluation of Novel Small-Molecule Targeted Agents for the Prevention and Treatment of Prostate Cancer." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243948876.

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Al-Amer, Saleh Suliaman. "Nutritional and toxicological studies on New Zealand mutton bird meat (Puffinus griseus)." Lincoln University, 2009. http://hdl.handle.net/10182/1659.

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New Zealand mutton bird or tītī (Puffinus griseus and order procellariiformes) nest in New Zealand during the summer months, migrate to the northern hemisphere during May and return in September. Their eggs are laid during November and December and the chicks are hatched in the following January and February. Large numbers of them are harvested from April to May in New Zealand. They are wild seabirds annually harvested by Maori according to the customary rights agreement set by Treaty of Waitangi.NZ mutton birds also called Sooty Shearwaters are noted for their high proportion of body fat.These birds are interesting since its sole diet is based on krill and other small marine organisms that are potentially rich in n-3 fatty acids and other marine bioactive compounds. The proximate composition, fatty and amino acids and cholesterol content of mutton bird pectoral muscle were determined and compared with other common meat to explore the nutritional value of this New Zealand delicacy. The concentration of twenty two essential and toxic elements including silver (Ag), aluminium (Al), arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), manganese (Mn), lead (Pb), selenium (Se), potassium (K), calcium (Ca), magnesium (Mg), boron (B), iron (Fe), nickel (Ni), sulphur (S), sodium (Na) and cobalt (Co) and zinc (Zn) in mutton bird breast meat (Puffinus griseus) were measured over two years to evaluate its safety for human consumption. Persistent organochlorine, dichlorodiphenyltrichloroethane (DDT) and their metabolites, and aldrin and lindane were also measured.Twenty bird carcasses were purchased in both 2006 and 2007 from a local source. Meat samples from the pectoral muscle of two carcasses were pooled to generate 10 samples for each year. These were used for trace element analysis using inductively coupled plasma-mass spectrometry (ICP-MS). Trace elements were in the range of 0 to 1.09 mg/kg wet weight for Ag, 0 to 3.32 for Al, 0.17 to 0.79 for As, 0.01 to 0.07 for Cd, 0.03 to 0.15 for Cr, 3.56 to 4.88 for Cu, 0 to 0.15 for Hg, 0.22 to 0.50 for Mn, 0 to 0.09 for Pb, 0.66 to 1.18 for Se and 11.49 to 23.70 for Zn. In 2006, Ag, Al, Mn and Zn concentrations were significantly higher but Pb and Hg concentrations significantly lower compared to the 2007 samples (P < 0.05). Apart from one sample in 2006, all the samples were below the published maximum level for concern. However, our preliminary data indicated that the higher level of Cd and other metals in the skin of mutton bird may compromise the overall safety to humans consuming the skin of mutton birds. It is suggested that the evaluation of the metals in different parts and/or the whole mutton bird at different seasons is required to assure complete safety to the consumers.Furthermore, the nutritional value of mutton bird meat was studied over two harvesting seasons (2006 and 2007) to investigate the impact of seasonal variation. The moisture and carbohydrates contents ranged between 54.0 to 55.0 % and 2.8 to 3.0 %, respectively, and no seasonal effects were evident in these components. The values for fat and ash contents were higher and the protein content lower for birds harvested in 2007 compared with the 2006 values which ranged from 11.8 to 13.0, 10.3 to 11.7, and 20.3 to 18.5 % for fat, ash and protein content respectively. The major amino acids in mutton bird pectoral muscle were glutamate, aspartate, lysine, leucine, and arginine. Higher lysine concentrations and lower proline, cystein and methionine were found in mutton birds compared with the literature values for beef, lamb and pork. The essential amino acid content in mutton bird (43.8 and 44.9 % in 2006 and 2007, respectively) was slightly higher than those found in beef and lamb meats (42-43%).The major fatty acids detected were palmitic (C16:0), stearic (C18:0), oleic and isomers (C18:1), eicosenoic (C20:1), Docosahexaenoic acid (DHA) (C22:6), icosapentaenoic acid (EPA) (C 20:5) and these accounted for approximately 77% of the fatty acids. The 3/6 ratio of fats from pectoral muscle was 1.3. The cholesterol concentration varied slightly in the two years with 184.4±37.37and 134.4±25.55mg/100 g fresh weight for 2007 and 2008 respectively. Mutton bird was shown to contain significantly higher cholesterol content (134.4-184.4) than other common meat such as chicken (80.3-88.9), lamb (62.3), fish (52.79) and beef (51.97). Overall, the nutritional value of mutton bird muscle was similar to or superior to the traditionally protein sources such as seafood and red meat. Annual variations existed in the composition of Mutton bird pectoral muscle but this is not of nutritional consequence but might be a useful indicator for ecological events such as feed availability and other environmental issues. Mutton bird seems to be a good source of essential minerals, Zn and Fe compared with other traditional meats source. Mutton bird meat is nutritionally as good as the major sources of red or white meats. It may even have advantages over the other common meats (beef, lamb, fish and chicken) due to its high protein and monounsaturated fatty acids (omega n-3 and n-6) content. However, its high cholesterol content may represent a risk factor for some people.
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Winstanley, Peter Andrew. "The pharmacology and toxicology of amodiaquine." Thesis, University of Liverpool, 1988. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237571.

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Lepera, Michael Anthony. "Response of Monovalent Cation Transporters to Pro-apoptotic Protein Kinase C Modulators in Human Lens Epithelial Cells." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1314376525.

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Wang, Jinju. "Differentiation of Megakaryocytes/Platelets and Neurons from Human Endometrial Stromal Progenitor Cells." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1314976408.

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Books on the topic "Veterinary Toxicology and Pharmacology"

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European Association for Veterinary Pharmacology and Toxicology Congress (3rd 1985 Ghent, Belgium). Comparative veterinary pharmacology, toxicology and therapy. Boston: MTP Press, 1985.

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Van Miert, A. S. J. P. A. M., M. G. Bogaert, and M. Debackere, eds. Comparative Veterinary Pharmacology, Toxicology and Theraphy. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3.

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Botsoglou, Nikolaos A. Drug residues in foods: Pharmacology, food safety, and analysis. New York: Marcel Dekker, 2001.

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Congress, European Association for Veterinary Pharmacology and Toxicology. Comparative veterinary pharmacology, toxicology, and therapy: Proceedings of the 3rd Congress of the European Association for Veterinary Pharmacology and Toxicology, August 19-25, 1985, Ghent, Belgium. Lancaster, England: MTP Press, 1986.

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European Association for Veterinary Pharmacology and Toxicology. Congress. Proceedings of the 6th International Congress: Edinburgh, UK, 7-11 August 1994. Oxford: Blackwell Scientific Publications, 1994.

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European Association for Veterinary Pharmacology and Toxicology. Congress. Proceedings of the 7th European Association for Veterinary Pharmacology & Toxicology (EAVPT) International Congress: Madrid, Spain, 6-10, July 1997. Edited by Anadón Arturo, McKellar Quintin, and European Association for Veterinary Pharmacology and Toxicology. Oxford: Blackwell Scientific Publications, 1997.

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Sjoberg, Per. Studies on the disposition and testicular toxicity of di-(2-ethylhexyl) phthalate. Uppsala: Sveriges Lantbruksuniversitet, 1985.

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Jonsson, Curt-Johan. Activation and toxicity of adrenocorticolytic DDT-metabolites in mammals and birds. Uppsala: Sveriges Lantbruksuniversitet, 1993.

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Schomburg, Dietmar. Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases: EC 3.4–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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Schomburg, Dietmar. Class 2–3.2 Transferases, Hydrolases: EC 2–3.2. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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Book chapters on the topic "Veterinary Toxicology and Pharmacology"

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Droumev, D. "Postgraduate training in the veterinary pharmacology." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 47–55. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_5.

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Baggot, J. D. "The teaching of veterinary pharmacology and toxicology." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 57–66. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_6.

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Jager, L. P., E. J. Van der Molen, G. J. De Graaf, T. H. J. Spierenburg, M. J. A. Nabuurs, and A. J. Baars. "Pharmacology of carbadox in the pig." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 435–43. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_41.

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Ooms, L. A. A., A. Weyns, A. Degryse, and Y. Ruckebusch. "Pharmacology of the (fore)-stomach smooth muscles." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 107–21. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_11.

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Ruckebusch, Y., T. Bardon, C. Cherbut, M. Pairet, and J. P. Ferré. "Smooth muscle pharmacology of the large intestine." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 123–32. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_12.

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Breimer, D. D. "Potential of new drug delivery systems in veterinary medicine." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 75–84. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_8.

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Fink, J. "Regulation of drug usage in veterinary medicine: the situation in Germany." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 521–26. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_49.

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Watson, A. D. J. "Influence of food on absorption of antimicrobial drugs." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 93–104. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_10.

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Hall, L. W. "Effects of halogenated inhalational anaesthetics on respiration in dogs." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 25–32. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_3.

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Gasthuys, F., A. De Moor, and C. Van Den Hende. "Influence of halothane anaesthesia, after xylazine premedication, on serum calcium concentration in the horse." In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 3–12. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_1.

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Conference papers on the topic "Veterinary Toxicology and Pharmacology"

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Shumilina, M. A., K. A. Nefedova, and A. L. Zolkin. "VETERINARY EDUCATION AS A COMPONENT OF MODERN HIGHER SCHOOL IN RUSSIA: A BRIEF RETROSPECTIVE FLASHBACK OF PRE-INDUSTRIAL DEVELOPMENT." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-247-249.

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The article provides a brief historical event series of the formation of the modern appearance of higher veterinary education in Russia - in the Russian Empire and Soviet Russia. Some institutional measures for the formation of a higher school of veterinary medicine, which served as the basis for the subsequent development of veterinary medicine as a scientific direction, are considered. Key words: veterinary
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Moiseeva, A. A., V. N. ,. Skvortsov, and A. A. Prisnyi. "EFFECT OF ENROFLOXACIN ON WHITE BLOOD CELL DYNAMICS IN YOUNG POULTRY." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-168-170.

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Analysis of hematological profile of poultry may serve as a tool for monitoring the impact of various medicinal drugs on the organism and for detection of their unknown effects. We studied the obtained blood parameters while bearing in mind our goal to extend knowledge of the impact of fluoroquinolones on the organism of different kinds of poultry in view of certain lack of such knowledge especially for poultry of young ages.
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Lutsko, T. P., A. V. Osipova, and D. A. Skvortsov. "FEATURES OF CONCENTRATION OF SOME HEAVY METALS BY SORBENTS BASED ON VERMICULITE IN HYDROSPHERE OBJECTS." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-151-151.

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The problem of water quality occupies a crucial place in the system of nature protection and public health. Due to anthropogenic activities, heavy metals are one of the most common pollutants of natural waters. The natural mineral vermiculite has proven to be an effective absorber of trace amounts of heavy metals.
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Yeganyan, E. S. "STUDY OF THE EMBRYOTOXIC AND TERATOGENIC EFFECTS OF THE FEED ADDITIVE ABIOPEPTIDE-PLUS." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-74-76.

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The author of this article studied the embryotoxic and teratogenic properties of the feed additive Abiopeptide-plus on chicken embryos. It was found that the feed additive does not have negative consequences in the development of chicken embryos and contributes to the formation of a healthy full-fledged chicken.
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Kraskov, D. A., and T. P. Lutsko. "TOXIC-ECOLOGICAL ANALYSIS OF WATER IN THE GULF OF FINNISH." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-153-154.

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The Gulf of Finland plays an important role in many aspects of the activities of people living in St. Petersburg and the Leningrad region, based on this, it is necessary to control the chemical composition of the waters of the Gulf of Finland in order to avoid unwanted complications from animal health.
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Lutsko, T. P., A. G. Polyanskikh, E. S. Kuzmina, and I. D. Volobuev. "COMPARATIVE ANALYSIS OF THE HYDROCHEMICAL INDICATORS OF THE WATERS OF THE FINSKIY BAY IN THE AREA OF ST. PETERSBURG." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-150-151.

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Now the Finskiy bay is actively used for the everyday needs of the population of St. Petersburg. Therefore, in various districts of the city, a hydrochemical analysis of the waters of the Finskiy bay was carried out and the concentrations of nitrates, nitrites, ions of copper, iron, silicon, ammonium, as well as carbonate hardness and pH were determined. As a result of the study, it was found that all studied parameters, except for iron ions, do not exceed the MPC.
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A. A., Belov, A. V. Deryugina, and M. N. Ivashchenko. "CORRECTION OF TECHNOLOGICAL STRESS BY LOW-INTENSITY LASER RADIATION." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-24-25.

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Intensive industrial technologies in animal husbandry lead to an increase in cases of stress and metabolic disorders, which affects the quality of dairy and meat products. It is important to increase the resistance of animals to environmental factors by non-drug methods. The aim of the work is to study the effect of technological stress and low-intensity laser radiation at the cell level.
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Brigida, A. V., and O. A. Skachkova. "THE RELEVANCE OF THE APPLICATION OF FSH FOR SUPEROVULATION OF DONOR COWS AND WAYS OF INCREASING ITS EFFICIENCY." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-28-30.

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In the technology of cattle embryo transplantation, the classic protocol for superovulation of embryo donor cows is used, based on 8-10-fold administration of follicle-stimulating hormone (FSH) every 12 hours for 4-5 days. For many decades of using this technology, the yield of high- quality embryos varies within 4-6 pcs. It is necessary to increase the effectiveness of FSH to increase the number of embryos. We conducted a study of the effectiveness of a pharmacological composition consisting of FSH combined with polyethylene glycol (PEG) with a molecular weight of 6000 Da, which increases the yield of the number of embryos obtained, suitable for transplantation into recipients, or their cryopreservation
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Kuzmina, T. I., D. N. Tatarskaya, and V. YU Kravtsov. "PROSPECTS FOR THE USING OF SILICON-CONTAINING COMPOUNDS IN THE TECHNOLOGY OF IN VITRO MATURATION OF ANIMAL OOCYTES." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-129-131.

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In vitro production of animal embryos is an important tool for solving male and female infertility problems in animals. Modeling of extracorporeal maturation systems of oocytes using siliconcontaining compounds in the composition of culture media revealed the peculiarities of the realization of their effects on somatic and germ cells of ovarian follicles, depending on the structure. Highly dispersed silica nanoparticles (nHDS) positive effects on the fertility of female gametes in Bos Taurus and Sus Scrofa Domesticus. The gel substrate of silica (silicon dimethylglycerolate - DMGC) does not cause an increase in the level of embryos cleavage, while it does not have cytoand genotoxicity when tested on somatic and germ cells of antral follicles.Key words: siliconcontaining compounds, in vitro maturation, animal oocytes.
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Sakhno, T. A., M. P. Semenenko, and V. N. Grin. "DYNAMICS OF BIOCHEMICAL INDICATORS OF BLOOD IN FRESH COWS ON THE BACKGROUND OF HEPATOPROTECTOR APPLICATION." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-211-212.

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The influence of a new injectable hepatoprotective drug livasen in the prevention of hepatosis in highly productive fresh cows has been studied. The performed pharmacoprophylaxis has shown high efficiency in the correction of diseases of the hepatobiliary system and metabolic insufficiency.
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Reports on the topic "Veterinary Toxicology and Pharmacology"

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Munavalli, Shekar, Dennis K. Rohrbaugh, and H. D. Durst. Chemistry, Biochemistry, Pharmacology, and Toxicology of CS and Synthesis of Its Novel Analogs. Fort Belvoir, VA: Defense Technical Information Center, October 2007. http://dx.doi.org/10.21236/ada474594.

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