Dissertations / Theses on the topic 'Veterinary Medicine'
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Wyse, Cathy. "Exhaled breath microanalysis in veterinary medicine." Thesis, University of Glasgow, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433584.
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Bidaisee, Satesh. "Females in veterinary medicine : why the choice?" Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/7621/.
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Veterinary Medicine as a profession has undergone a change from a male-oriented one, to being predominantly female. The increase in female students is a reflection of the increasing interest in veterinary medicine by females. This study focused on reasons for the specific choice of veterinary medical education among female veterinary students. A life history approach was applied in order to explore the lives of six female veterinary students from St. George’s University, School of Veterinary Medicine in Grenada. This methodology involved using interviews to collect personal accounts of students’ life experiences that provided data about the reasons for the choice of female students to pursue veterinary medical education. The theoretical framework that served as the base for this thesis was grounded theory. Interviews were transcribed, exerted to concept identification, data reduction, and thematic representations for analysis. The study revealed that life experiences as well as socio-cultural realities surrounding the lives of the students were crucial in understanding the influences and reasons for their choice of veterinary medicine. A Life Stages Theory emerged from the use of grounded theory approach to data analysis which identified personal, financial and academic needs as primary to create interest in veterinary medicine. The experiential enquiry into the students’ lives also recognized pet ownership, exposure to knowledge of veterinary medicine as well as positive perceptions of veterinarians and veterinary medical practice as reasons for the choice of veterinary medicine. The final choice of veterinary medicine by females was found to be based on their personal interests, their ability to overcome financial and academic barriers and receive opportunities of alternative academic pathways. The new insights created on reasons for the choice of veterinary medicine can be applied to student career advisement and review of applicants for admission into veterinary schools.
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Lambertini, Carlotta <1987>. "New applications of alpha2-agonists in veterinary medicine." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8427/2/tesi%20CLambertini.pdf.
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Alpha2-agonists are a class of drugs widely used in veterinary anaesthesia; moreover by means of their action on adrenoceptors that are widespread distributed in several tissues, they can be beneficial for different clinical applications. The aim of this work was to describe new applications of alpha2-agonists in veterinary medicine.
In cats, high dose medetomidine is administered to perform semen collection by urethral catheterization. We have investigated the haemodynamic effects of high dose medetomidine (0.13 mg kg-1) administered to healthy male cats. Haemodynamic evaluations were performed before and after medetomidine administration and consisted of: clinical examination, blood pressure evaluation and transthoracic echocardiography. Significant hemodynamic alterations were observed, even if they were similar to that provided by lower dosages. The cats recovered without clinical alterations.
Despite their cardiovascular side effects, low doses of alpha2-agonists can be beneficial for the maintenance of a good cardiovascular stability for specific conditions.
In humans, dexmedetomidine helps in maintaining a good hemodynamic stability if administered for pheochromocytoma ablation. We have described the administration of dexmedetomidine for the anesthetic management of two dogs with a suspicion of pheochromocytoma undergoing adrenalectomy. Dogs received dexmedetomidine intramuscularly (0.001 mg kg-1) and dexmedetomidine and remifentanil were administered (0.0005 mg kg-1h-1 and 0.0003 mg kg-1min-1, respectively) throughout the surgery. In this study dexmedetomidine infusion together with remifentanil provided satisfactory intraoperative anesthetic and hemodynamic control in two dogs with a suspicion of pheochromocytoma.
In patients undergoing craniotomy, dexmedetomidine, increasing the cerebral vascular resistance, prevents alteration of the cerebral blood flow. We have described the administration of dexmedetomidine in five Macaca fascicularis undergoing craniotomy for physiologic research. The Macaca were sedated with ketamine (8 mg kg-1) and dexmedetomidine (0.02 mg kg-1) intramuscularly. Dexmedetomidine was administered by infusion (0.012 mg kg-1h-1) throughout the procedure and provided adequate analgesia and a stable hemodynamic control in healthy Macaca.I farmaci alfa2-agonisti sono largamente utilizzati in anestesia veterinaria; inoltre, grazie alla loro azione sui recettori alpha-adrenergici, distribuiti in diversi tessuti, sono utilizzati per diverse applicazioni cliniche. L'obiettivo del presente studio è stato quello di descrivere nuove applicazioni degli alfa2-agonisti in medicina veterinaria. Nel gatto, la medetomidina somministrata ad alte dosi consente la raccolta del seme mediante cateterismo uretrale. Abbiamo valutato gli effetti emodinamici della medetomidina somministrata al dosaggio di 0.13 mg kg-1 in gatti sani. Le valutazione emodinamiche sono state eseguite prima e dopo la somministrazione di medetomidina mediante visita clinica, misurazione della pressione sistemica ed ecocardiografia transtoracica. Dallo studio sono state evidenziate alterazioni emodinamiche significative, ma simili a quelle riportate dopo somministrazione di dosi più basse. I farmaci alpha2-agonisti, nonostante le alterazioni cardiovascolari che inducono, se somministrati a basse dosi, possono contribuire al mantenimento di una buona stabilità emodinamica in condizioni cliniche specifiche. Nell'uomo, la somministrazione di dexmedetomidina in pazienti sottoposti a rimozione di un feocromocitoma contribuisce a mantenere parametri emodinamici intraoperatori stabili. Abbiamo descritto la somministrazione perioperatoria di dexmedetomidina in due cani sottoposti a surrenalectomia per un sospetto di feocromocitoma. Entrambi hanno ricevuto dexmedetomidina intramuscolo (0.001 mg kg-1) e dexmedetomidina e remifentanil sono stati somministrati in infusione (0.0005 mg kg-1h-1 e 0.0003 mg kg-1min-1, rispettivamente) per tutta la chirurgia. Il protocollo utilizzata ha permesso di mantenere un piano anestesiologico e condizioni emodinamiche stabili in due cani con sospetto di feocromocitoma. Nei pazienti sottoposti a neurochirurgia, la dexmedetomidina previene alterazioni significative del flusso cerebrale. Abbiamo descritto la somministrazione di dexmedetomidina in esemplari di Macaca fascicularis sottoposti a craniotomia. I macachi sono stati sedati con ketamina e dexmedetomidina. La dexmedetomidina è stata somministrata in infusione continua (0.012 mg kg-1h-1) per tutta la procedura e ha permesso di mantenere un'analgesia adeguata e parametri emodinamici stabili in macachi sani.
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Villamil, José Armando Henry Carolyn J. "Use of the veterinary medical database to update the veterinary oncology literature." Diss., Columbia, Mo. : University of Missouri-Columbia, 2009. http://hdl.handle.net/10355/6741.
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The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on March 25, 2010). Vita. Thesis advisor: Carolyn J. Henry. "December 2009" Includes bibliographical references.
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Gardiner, Andrew A. "Small animal practice in British veterinary medicine 1920-1956." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532236.
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PIGOLI, CLAUDIO. "MYCOBACTERIAL DISEASES IN VETERINARY MEDICINE: MORPHOPATHOLOGY AND MYCOBACTERIAL PHENOTYPES." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/843675.
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Mycobacteria are an ancient bacterial taxon that has, over time, had a profound impact on mankind and domesticated animals. Mycobacteria are, in fact, responsible for significant human and animal diseases whose severe economic and public health repercussions make them still highly topical today.
The first topic of research in this Thesis is a widely characterized phenomenon in the context of human tuberculosis, but one which has, to date, been little considered in animal tubercular infections, namely mycobacterial dormancy. As bovine tuberculosis (bTB) is undoubtedly the most significant of the animal tubercular infections, these aspects have been investigated precisely in the context of this pathology. In particular, this study aimed to verify the intralesional existence of non-acid-fast (non-AF) mycobacteria phenotypes that in human medicine have been associated to the phenomenon of mycobacterial dormancy. Another important objective of this study was to develop a histological method capable of detecting in the same section the mycobacterial cells by combining AF stains and techniques capable of highlighting the mycobacteria regardless of their AF features. In this retrospective study, 250 bovine lymph nodes (LNs) in which Mycobacterium bovis (Mb) has been identified by the diagnostic algorithm routinely applied by the Italian National Reference Center for bTB, were randomly enrolled. Ziehl-Neelsen (ZN) stained sections were evaluated for each sample. Only LNs with at least one granuloma containing more than 20 ZN-positive bacilli were selected, and the corresponding formalin-fixed and paraffin-embedded blocks were retrieved. For each block, a 4-µm thick section was obtained and, after reducing the autofluorescence through a photobleaching protocol and unmasking the Mb antigens with enzymatic digestion, the sections were submitted to a protocol combining Auramine O stain and an indirect immunofluorescence assay targeting Mb antigens; a DAPI-containing mounting medium was used. Processed slides were viewed with a Leica DM6 B upright microscope, and the obtained images were elaborated with a deconvolution algorithm. Of the 250 enrolled LNs, 24 contained at least one granuloma with more than 20 ZN-positive bacilli, and in all of them, AF and non-AF bacilli were identified. In all (24/24) selected LNs, the non-AF bacillary load resulted greater than the AF one, especially in the central parts of the granuloma; non-AF bacilli were also identified within the cytoplasm of multinucleated giant macrophages (MGMs). This study revealed for the first-time non-AF Mb phenotypes within bovine lymph nodal granulomatous lesions. It also demonstrated that a widely studied pathology such as bTB still poses new issues regarding pathogenesis and host-pathogen interaction and suggested that bTB can be considered an effective animal model for studying mycobacterial dormancy.
The second study carried out was also focused on a tubercular infection but, in this latter case, both the mycobacterial species involved and the affected host were different. Indeed, in the second study, wild boar (WB) M. microti (Mm) infection, whose epidemiological and pathogenic dynamics are still largely unknown, was enquired into. Specifically, the natural WB Mm infection was investigated by evaluating the granulomatous lesions' histological features and Mm microbiological isolation. For this purpose, 103 WB retropharyngeal and submandibular LNs in which Mm was identified by gyrB restriction fragment length polymorphism PCR were retrospectively selected and histologically assessed. For each sample, Hematoxylin-eosin and ZN-stained slides were evaluated. Considered histological variables were the number of granulomas, size and maturational stage of granulomas, number of MGMs, and AF bacilli per granuloma. Furthermore, Mm microbiological results were also considered. Investigated parameters were statistically analyzed. Mm microbiological isolation was negatively influenced by granulomas maturation and positively affected by AF bacilli's presence within the section. Granuloma maturation was positively influenced by granuloma size and negatively affected by the number of granulomas in the section and the number of MGMs within the granuloma. The obtained results indicate that granulomas' maturation ensured an efficient containment of Mm infection in the WB, making the intraspecific transmission of the disease an unlikely event.
Finally, an outbreak of paratuberculosis in a group of scimitar-horned oryxes (SHOs) kept in a zoological park, gave us the chance to describe various aspects of this disease in an endangered animal species subject to an international conservation and reintroduction plan encompassing several countries. In particular, after the death of six of the 10 SHOs, serial investigations of dead and alive animals were performed. Necropsy, carried out on five out of six animals, identified intestinal thickening and mesenteric lymphadenomegaly in one of the animals. Histopathology (5/6) revealed lepromatous (2/5) and tuberculoid (2/5) intestinal forms or lack of lesions (1/5). ZN and immunohistochemistry stains identified two multibacillary, two paucibacillary forms, and one negative case. M. avium subsp. paratuberculosis (Map) was identified by quantitative PCR (qPCR) in tissue samples in five out of five SHOs and was microbiologically isolated from two of the three animals whose fresh tissue samples were available. Fecal samples were collected in four of the six dead animals: all four resulted positive to qPCR and Map was isolated in three. ELISA identified Map-specific antibodies in three of the five dead animals whose serum was available. qPCR identified Map in the freshly deposited feces of two out of the four alive animals. From the feces of these two animals, Map was microbiologically isolated in one case. All isolates were classified as Map type C and profiled as INMV2 and MVS27 by molecular analysis. Genomic analysis of a field isolate revealed clusterization with a European clade but was more similar to Italian than East European isolates. Our findings highlight again that paratuberculosis should always be considered in zoological parks where endangered species are hosted. Infection can be subclinical, and multiple combined testing techniques may be necessary.
The studies included in this Thesis made the examination of certain aspects of significant animal mycobacterial diseases possible, and the results obtained demonstrate that a multidisciplinary approach is the best option when studying infectious diseases, and this is especially true in case of infections deserving to be managed in a One Health perspective.
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Jeyaretnam, Joseph S. "Occupational hazards and radiation safety in veterinary practice including zoo veterinary practice in Australia." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2003. https://ro.ecu.edu.au/theses/1306.
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This thesis contains reviews and research on the occupational hazards of zoo veterinary practitioners in Australia. Although occupational hazards have long been recognised in the veterinary profession, little information is available on the number and magnitude of injuries to veterinarians in Australia, the United Kingdom or the United States. Apart from anecdotal accounts and some limited data, most of the available information is on occupational zoonoses, generally well recognized by veterinarians. Other occupational hazards to which veterinarians are exposed have received scant attention. The veterinary practitioner in a zoo environment has to treat a range of captive wild species which are much more unpredictable and dangerous than domesticated animals. A comprehensive study on occupational hazards sustained by veterinarians in zoological gardens has not been undertaken in Australia. Only one study had been undertaken in the US amongst zoo veterinarians, while comprehensive may not be able to be transposed to zoos in Australia as the species held in Australian zoos differ from those in the US. Personal communication with some senior veterinarians in the zoological gardens in Australia, have elicited further information on the prevalence of occupational hazards sustained by the zoo and wildlife park veterinarians. The prevalence of physical hazards including radiation, chemical and biological hazards reported by veterinary practitioners and the author's own experience as a veterinary practitioner, chairman of the safety committee, member of the animal ethics committee and manager, research In the zoological gardens in Perth, Western Australia have demonstrated a need for a comprehensive study on occupational hazards prevalent among zoo veterinarians. To investigate the occupational hazards including radiological hazards amongst zoo veterinarians in Australia, a self-administered 14-page comprehensive questionnaire comprising 58 questions was mailed to 27 practising zoo veterinarians in Australia. The questionnaire focused on physical injuries, chemical exposures, allergic and irritant reactions, biological exposures, radiological hazards including problems encountered with x-ray machines, use of protective gear and ancillary equipment for radiography, personnel involved in x-ray procedures and in restraining animals, compliance with the Australian National Health and Medical Research Council (NHMRC) Code of Practice (1982), Radiation Safety Regulations (1988) and National Standard for Limiting Occupational Exposure to Ionising Radiation (1995) The result of the study revealed that 60% of the participants sustained physical injuries such as crushes, bites and scratches inflicted by a range of species with some Injuries requiring medical treatment. Also, 50% of the participants suffered from back injuries while 15% reported fractures, kicks, bites necessitating hospitalization. Ninety percent of the participants sustained needlestick injuries ranging from one to 16+ times. Other significant findings include: necropsy injuries, animal allergies, formaldehyde exposure, musculoskeletal Injuries and zoonotic infections. The survey also identified that veterinary practitioners and their staff were exposed to radiation by not complying with the National Health and Medical Research Council (NHMRC) Australian Code of Practice for the Safe Use of Ionising Radiation (1982) which has been framed to minimize exposure to ionising radiation. The majority of the veterinarians in the study group indicated that radiation exposure Is a major occupational hazard to the veterinary profession. Subsequent to the review and research, discussions were held with few senior zoo veterinarians, the Registrar of the Veterinary Surgeons Board and a number of practising senior veterinarians In Australia to collect information on occupational hazards. Additional information was obtained on occupational injuries sustained by the zoo veterinarians through formal discussions with the Director and the two senior veterinarians In the zoological gardens in Sri Lanka. The discussions with the veterinary practitioners in government and private practice revealed that veterinarians experienced a range of occupational hazards including exposure to rabies. Discussions with the dean and the professor of the animal science department focused on the nature of injuries and preventive strategies. In order to obtain information on occupational hazards in the health care industry, the professor of anatomy of the faculty of medicine and a senior surgeon in Sri Lanka were interviewed. This study identified that the zoo veterinarians are routinely exposed to a wide range of occupational hazards. The literature review among veterinary practitioners In US, UK, Australia and Canada have also identified numerous occupational hazards sustained by the veterinarians. The discussions held in Sri Lanka with the professionals in veterinary and health care industry showed that occupational injuries have been common amongst them and they do not have appropriate preventive guidelines in place. This thesis has incorporated recommendations in the form of preventive strategies for minimizing occupational hazards among veterinary practitioners both in zoological gardens and veterinary practices In Australia and in the developed and developing countries.
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Hammill, Bess Catherine. "Veterinary anatomy laboratory impact study." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/11048.
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Thesis (M.S.)--West Virginia University, 2010.Title from document title page. Document formatted into pages; contains vii, 56 p. : col. ill. Vita. Includes abstract. Includes bibliographical references (p. 35-36).
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Reyes-Illg, Gwendolen. "Respect for Patient Autonomy in Veterinary Medicine| A Relational Approach." Thesis, Colorado State University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10640397.
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This thesis considers the prospects for including respect for patient autonomy as a value in veterinary medical ethics. Chapter One considers why philosophers have traditionally denied autonomy to animals and why this is problematic; I also present contemporary accounts of animal ethics that recognize animals’ capacity for and exercise of autonomy (or something similar, such as agency) as morally important. In Chapter Two, I review veterinary medical ethics today, finding that respect for patient autonomy is undiscussed or rejected outright as irrelevant. Extrapolating mainstream medical ethics’ account of autonomy to veterinary medicine upholds this conclusion, as it would count all patients as “never-competent” and consider determining their autonomous choices impossible; thus welfare alone would be relevant. Chapter Three begins, in Part I, by describing the ways we routinely override patient autonomy in veterinary practice, both in terms of which interventions are selected and how care is delivered. I also show that some trends in the field suggest a nascent, implicit respect for patient autonomy. Part II of Chapter Three presents feminist criticisms of the mainstream approach to patient autonomy. I argue that the relational approach to autonomy advocated by such critics can be meaningfully applied in the veterinary realm. I advance an approach that conceives respect for patient autonomy in diachronic and dialogic terms, taking the patient as the foremost locus of respect. In Chapter Four, I turn to issues of practical implementation, such as interpreting what constitutes an animal’s values and concerns, and assessing the effect of positive reinforcement training on autonomy. The Conclusion offers areas for future research while refuting the objection that a simpler, expanded welfare-based approach would yield the same substantive recommendations as my account.
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Barachetti, L. "AMNIOTIC MEMBRANE TRANSPLANTATION FOR OCULAR SURFACE RECONSTRUCTION IN VETERINARY MEDICINE." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150198.
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The fetal membrane is composed by the chorion, allantois and amnion. The AM is the inner layer. It consists of a single layer of ectodermally derived cuboidal to columnar cells, which form the epithelium, a basement membrane that connects with the chorion by a layer of mesenchyme which contains large amounts of collagen (stroma). Amniotic basement membrane and stroma contain cytokines, proteoglycans, collagen type I, III, IV, V and VII, laminin and fibronectin.
Different interesting properties of the AM have been described. Amniotic basement membrane, by serving as a “transplanted basement membrane”, acts as a new healthy substrate that facilitates migration of epithelial cells, reinforces adhesion of basal epithelial cells, promotes epithelial differentiation, and prevents epithelial apoptosis. Additionally AM produces various growth factors, inhibits protease activity, has anti-inflammatory, anti-angiogenic and antifibrotic effects. The non-immunogenicity of the AM was believed to be another important property. AM transplantation (AMT) has been widely described in human ophthalmology for the reconstruction of corneal and/or conjunctival surface in different diseases, such as: ocular surface neoplasia, pterygium, chemical and thermal burns, cicatrizing conjunctivitis, symblepharon release, bleb leakage, filtering surgery, persistent epithelial defects, non healing stromal ulcers, deep stromal ulcers and descemetoceles, neurotrophic keratopathy, limbal stem cells deficiency, bullous keratopathy, infectious keratitis, Stevens Johnson syndrome, melting ulcers, scleral melt and band keratopathy. In veterinary ophthalmology AMT has been described for the treatment of ocular surface neoplasia, bullous keratopaty, melting ulcers, symblepharon, immun-mediated keratitis and in conjunction with penetrating keratoplasty. The objective of our study was to evaluate the effects of amniotic membrane transplantation for reconstruction of the ocular surface in different diseases in dogs, cats and horses. We evaluated the cosmesis and visual function. In our case series we performed AMT with the inlay technique in 3 dogs (3 eyes), 6 cats (7 eyes) and 11 horses (11 eyes). The diseases treated were: 7 feline corneal sequestra, 4 corneal melting (1 dog and 3 horses), 2 dermoids (2 dogs), 4 keratomycosis (4 horses), 2 corneo-conjunctival squamous cell carcinoma (2 horses), 1 immunomediate keratitis (1 horse) and 1 corneal edema (1 horse). In our results the objective was obtained: we had successful outcome in 17 of the 21 eyes treated; no ocular pain was detected in the immediately postoperative period, the AM epithelialized quickly and, after the fibrovascular invasion of the AM, all the corneas obtained a good transparency and no recurrence was detected in our follow-up periods.
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Folk, Lillian C. "A study of the Veterinary Medical Database /." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p1421133.
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Hammond, Jennifer. "Training for uncertainty in veterinary education." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/9000/.
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This thesis addresses the question of how veterinary students learn to cope with uncertainty in professional practice. There is currently a lack of clarity in discussion of what constitutes effective coping with uncertainty in veterinary practice and indeed how this might be taught or assessed as part of the veterinary education process. This is despite wide recognition that managing uncertainty is central to practice in the health professions, reflected in the fact that the ability to cope with uncertainty is considered a “day one competency” for veterinary surgeons. This research adopted both extensive and intensive perspectives to address the central research question. Orienting concepts were developed form the literature on workplace learning, approaches to clinical uncertainty and individual differences in tolerance of uncertainty and ambiguity. The extensive perspective used a survey study to describe tolerance of ambiguity among veterinary students at a UK veterinary school. On average, ambiguity tolerance did not change during the classroom based part of veterinary training. Individual trajectories were often more erratic and some students moved between the highest and lowest categories during the course of training. Previous education and status as a mature student were both associated with greater tolerance of ambiguity, suggesting that educational and life experiences can produce changes in this disposition. The intensive perspective comprised a qualitative case study, using clinical case discussion recordings and semi-structured interviews to develop an understanding of the mechanisms which influence learning to cope with uncertainty in the context of an international elective placement. Using the language of situated learning theory, learning to cope with uncertainty was described as legitimate peripheral participation in the uncertainty work of a community of practice. Uncertainty work is a novel concept used to describe navigating ambiguity, complexity and risk in professional practice . Using this theoretical framework to draw together findings from both intensive and extensive perspectives suggested the central role of gaining access to uncertainty work in professional learning. Generative mechanisms have been proposed to explain the empirical findings. Access to uncertainty work was negotiated between students and staff in the context of clinical and educational practice. Trust was central to gaining access to uncertainty work, and this was reflected in increasing clinical responsibility. Ambiguity tolerance was described in this context as a disposition of individuals which can influence their engagement with and access to uncertainty work. Through an exploration of the significance of these mechanisms in the context of Veterinary education, implications for curriculum and policy have been highlighted. Although the use of measures of ambiguity tolerance in selection are considered problematic, there can be clear scope to support students in accessing uncertainty work and to highlight encounters with uncertainty work as integral to the professional role, providing opportunities to promote personal and professional development through reflective practice.
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Denagamage, Thomas Nishantha. "Application of evidence-based medicine to veterinary science and food safety." [Ames, Iowa : Iowa State University], 2008.
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Rathinasabapathy, G., and L. Rajendran. "Web-based Digital Resources for Small Animal Medicine Professionals." e-Science World, 2009. http://hdl.handle.net/10150/299578.
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The Internet which is also known as ‘Information Superhighway’, ‘Global
Information Infrastructure’, ‘Cyberspace’, ‘Hyperspace’ etc., connects
millions of computers in a web and makes almost immediate
communication possible, irrespective of the location of its users. The
Internet provides huge resources that are useful for veterinary and animal
science professionals and the amount of accessible veterinary medicine
information is increasing rapidly. Ideally, this could provide a formidable
opportunity for Veterinarians to exchange and process veterinary
medicine information with colleagues around the world from their
desktop. Though the Internet offers virtually unlimited amount of
information related to small animal medicine and surgery and provides a
number of tools to access, it is useful in at least three aspects related to
veterinary medicine and surgery viz., communication, education and
research. This paper attempts to profile such important digital knowledge resources useful for small animal veterinary medicine professionals.
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Ortega, Meyer Bruno de Jesus. "A proposed framework for harmonization of the veterinary medicine curriculum in Latin America." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-2606.
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Dale, Vicki H. M. "Educational methods and technologies in undergraduate veterinary medicine : a case study of veterinary teaching and learning at Glasgow, 1949-2006." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/339/.
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This case study, of veterinary education at Glasgow between 1949 and 2006, was undertaken to provide an illustrative account of learning and teaching practices over time. Ultimately the aim was to inform discussions on curriculum reshaping in undergraduate veterinary education at Glasgow. A questionnaire was distributed to 2360 alumni, 513 students and 50 teachers, to obtain quantitative data on the availability and perceived usefulness of different educational methods and technologies, analysed using SPSS. Qualitative data were sought principally through ten student focus groups and interviews with over thirty current and former staff, theoretically coded using NVivo. Questionnaire responses (from 11.5% of alumni, 23.8% of students and 72% of teachers invited to participate) revealed that lectures, printed notes, tutorials, practical classes and clinical training were used consistently over time and rated highly by stakeholders, confirming the importance of didactic teaching methods coupled with discussion and practical hands-on experience. The focus groups with students highlighted their strong desire for earlier clinical training, with the recognition that a case-based approach resulted in more meaningful learning. The interviews with staff revealed that whilst all staff welcomed the opportunity for increased vertical integration, problem-based learning was rejected as a wholesale solution. Highlights of the school’s curricular innovations to date include the clinico-pathological integrated sessions, the lecture-free final year, and the introduction of a veterinary biomolecular sciences course that allowed for a seamless vertical integration in years 1 to 4. However, recent efforts to implement self-directed learning and assessment strategies have been hampered by the fact that these were isolated innovations set within a traditional teacher-centred paradigm. There was little support among stakeholders for undergraduate specialisation. There is still a perceived need for veterinarians to have omni-potential – if not to be omnicompetent. However, it is recommended that the current system of tracking be replaced with a more streamlined core-elective system, to allow students to pursue specific topics of interest in the later years of the course. Teachers and students cited attributes of ‘good’ teachers. These generally did not change over time, although technologies did change. Good communication appears to be central to good teaching, with an in-borne desire to enthuse and motivate students to learn for the pleasure of learning rather than the need to hurdle-jump examinations. Both teachers and students cited good teaching characteristics in terms of the teacher as authority and motivator, rather than as a facilitator of independent learning, reflecting the nature of the traditional, didactic course. There was little evidence of pedagogical change resulting from technological innovations. If anything, newer technologies compounded surface learning approaches and low level cognitive processing, rather than promoting deep learning and higher order thinking skills. Identified barriers to teaching innovations included lack of time, reward and support (for teachers and students). Future curricular innovation will require a substantial investment in the scholarship of teaching – rewarding staff for excellence in teaching, putting it on a par with research excellence, and ensuring the necessary support mechanisms and infrastructure are in place to ensure the success of a self-directed learning curriculum. A guided discovery learning curriculum is recommended, a compromise between traditional teaching and a fully problem-based curriculum. The study did not specifically focus on assessment, but it is recommended that learning, teaching and assessment practices should be constructively aligned.
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Perrin, Hannah Charmaine. "Rhetoric and reality : the development of professional identity in UK veterinary medicine." Thesis, University of Kent, 2016. https://kar.kent.ac.uk/54325/.
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Veterinary Medicine does not have a history in the social sciences and is therefore a fascinating field of study. Despite the growth of education research in the veterinary schools, the social and relational aspects of veterinary training and practice are under-examined, and could have profound effects on the ability of students to make a successful transition into qualified work. This thesis explored the development of occupational identity in veterinary students and newly-qualified veterinary surgeons, using narrative interview techniques and organisational policy analysis. From interviewees’ stories, a clear distinction could be drawn between the majority, who were vocationally-motivated, and a smaller group who were drawn to a veterinary career by the high academic standards required. All identified several influences on their own professional identity development: role models, the need to perform as competent and confident, and presenting an approved personality type in order to gain access to the practical experience required during training. The predominant story arc is that of becoming increasingly ‘vetlike’ as they progress through the course. Animal welfare is a substantial silence in the organisational discourse of veterinary medicine. The discourse analysis revealed the overwhelming presentation of the elite academic nature of the profession, at the expense of any mention of animal care or welfare, or acknowledgement of vocational motivation. A compelling collective responsibility was also identifiable in terms of upholding a professional reputation and its high standards. A strong occupational history contributes to this, leading to a very bonded occupational group. The idea of veterinary medicine not being a nine-to-five job is expressed in policy and resonated very strongly with interview participants. However, there exists a very clear, organisationally-sanctioned, officially-approved attitude towards veterinary life and work, allowing very little deviation. This has the subsequent effect that tolerance of weakness, unhappiness, or complaint is low; so that members are forced to either internalise their unhappiness or leave the profession entirely. Veterinary medicine is perceived as a career with high job satisfaction and a positive public image. However, awareness is increasing of worryingly high levels of mental illness, stress, unhappiness and dissatisfaction with their work among the veterinary workforce. This thesis suggests that one factor that could underlie this is a mismatch between a new entrant’s ideas of what a vet is and does, and the reality of a working life in veterinary practice. From the conclusions presented in this thesis - in particular the finding that, as a profession, veterinary medicine strives to distance itself from an animal care or animal welfare focus - I suggest that it is the confused messages received as part of the process of socialisation during training that could connect to many of the problems facing the modern entrant to the veterinary profession. This research specifically focused on the development of occupational identity in veterinary students and newly-qualified veterinary surgeons in the UK and is the only current work to examine the processes, presentation and experiences of veterinary training in this comparative manner. As a relatively new, and very interdisciplinary, field of study, the capacity for future work in veterinary social sciences is considerable, with much to be learnt from allied fields as well as further explorations of just what makes veterinary medicine unique, and such a valuable source of social inquiry given the significance of pets and livestock to the lives of a nation of animal lovers. This is potentially a very rich field.
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Hoare, Zoe Susannah Jane. "Feature selection and classification of non-traditional data : examples from veterinary medicine." Thesis, Bangor University, 2007. https://research.bangor.ac.uk/portal/en/theses/feature-selection-and-classification-of-nontraditional-data--examples-from-veterinary-medicine(f2a209be-9cb4-4dc8-9da5-0e2a66d28d70).html.
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Early diagnosis of notifiable diseases in the veterinary domain is important with regard to agriculture, the health sector and the economy. With no diagnostic test in the live animal for either BSE or Scrapie many cases may be mis-diagnosed. Traditionally, data for pattern recognition is stored as recorded cases of interest either labelled with their outcome (suitable for supervised classification) or unlabelled. Each case is described by a collection of symptoms, recorded as present / absent. These are called "binary features". In the case of medical data, the amount of cases recorded in this way may be limited for many reasons. To overcome this lack of data expert-estimated probability tables have been proposed as a substitute. These "non-traditional" tables contain the estimated percentage frequencies of clinical symptoms in various diseases. The construction of the tables assumed that the clinical signs (features) were independent given the diseases (classes). Given the "non-traditional" data, various feature selection techniques were applied and compared in this study in order to select a reduced subset of features (symptoms). The potential, limitations and stability of Sequential Forward Selection (SFS) in particular, were investigated. Decision trees and Naive Bayes classifier models were applied for the diagnosis task. The apparent success and stability of Naive Bayes in the medical domain led to an indepth investigation of the effects of this type of data and its inherent assumptions on the model. Naive Bayes is known to be optimal in the case of independent features, which is the condition assumed by the estimated probability tables in the "non-traditional" data. Various proposed adaptations to the Naive Bayes model were investigated with regard to their optimality when the independence assumption is violated. Finally, the performance of Naive Bayes with regard to traditionally stored medical data with binary features was assessed. Naive Bayes and its adaptations performed well with the traditional data. Since the effect of assuming independence when it is not true is minimal, using the "non-traditional" data with the Naive Bayes classifier can be a practical solution for veterinary diagnosis.
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DI, CESARE FEDERICA. "CLASSICAL AND POPULATION PHARMACOKINETICS OF ANTIMICROBIALS, SEDATIVES AND ANAESTHETICS IN VETERINARY MEDICINE." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/625676.
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Pharmacokinetics is defined as the use of mathematical models to quantitate the time course of drug absorption and disposition in man and animals. This discipline is the branch of pharmacology that aims to describe, through mathematics, the interactions and physiological processes (i.e. absorption, distribution, metabolism and excretion – the ADME process) that the drugs undergo after administration. When applied to a clinical situation, pharmacokinetics (PK) provides the clinician with important information on optimal drug dosages for each single patient.
In the present thesis, the focus moved to the importance of classical PK and its applications, starting from the theory and use of compartmental analysis and at the end arriving to illustrate the more recent notions of this discipline, popPK and PBPK, which are the most innovative topics in the clinical and translational pharmacology field.
The classical PK usually, translated clinically, is represented by quick studies which have a significant relevance in understanding ADME process of drugs with their desired, collateral or adverse effects. The population PK approach aims to investigate the influence of the interindividual variability in a target population of subjects, evaluating the populations characteristics that influence the fate of a drug after administration. The time required for the development of a popPK study applied to the clinical setting is much longer than a classical PK study.
Three studies of classical clinical PK and one population PK study were included in this thesis.
The first study concerned dexmedetomidine (DEX) and aimed to define the kinetic profile of this sedative following intravenous administration in a group of dairy calves, comparing its pharmacological and clinical effects with those of another a-2 agonist, xylazine, for minor surgical procedures.
The second study was related to the simultaneous administration, as preanaesthetics, of a mixture of DEX and methadone, an analgesic with a remarkable sedative efficacy belonging to the class of opioid μ-agonists. The aim was to establish the pharmacokinetic profile of this co-administration in dogs by oral transmucosal route and compare it with the intramuscular kinetic profile of the same drugs combination.
The third research addressed the species Panthera tigris. Since the literature concerning the non- domestic animals’ PK is lacking and needy of new information, specifically, the objective was to compare the kinetic profile of a simultaneous administration of DEX and ketamine, an injectable anaesthetic antagonist of NMDA receptors, following IM administration for chemical restraint in two groups of tigers.
The population PK study wanted to determine the popPK profile of cefazolin administered in a clinical setting for prophylactic purposes in 78 dogs, of different breed, age, weight, sex, body condition scores and health status, undergoing different surgical procedures. The ultimate goal was the definition of Clinical Breakpoints for this antimicrobial administered to the canine patient according to the guidelines of the Veterinary Committee on Antimicrobial Susceptibility Testing (VetCAST).
Finally, during these three years of PhD program, another popPK work has been started. This study is in collaboration with the veterinary anaesthesia Operative Unit of the University of Padua, which requested our laboratory for performing propofol quantification. The aim was the definition of the kinetic population profile of propofol, administered for the induction and maintenance of general anaesthesia with modern TCI technique, in order to determine a popPK model that would be applicable to dog anaesthesiology. Until now, propofol quantification has been accomplished, but the final popPK model is still under investigation (for this reason data are not reported in the thesis). In conclusion, the use of appropriate pharmacokinetic modelling was important to perform different types of studies which helped to provide the veterinary pharmacological literature with innovative data with wide clinical implications.
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Morse, Evan M. "Minority Student Perceptions of the Veterinary Profession: Factors Influencing Choices of Health Careers." Cleveland, Ohio : Cleveland State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1232135567.
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Thesis (M.A.)--Cleveland State University, 2008.Abstract. Title from PDF t.p. (viewed on Apr. 14, 2009). Includes bibliographical references (p. 82-86) and appendices. Available online via the OhioLINK ETD Center. Also available in print.
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Lourenço, Marisa Isabel da Costa. "Zoological species medicine." Master's thesis, Universidade de Évora, 2015. http://hdl.handle.net/10174/16445.
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Externship report done in order to describe and inform about the activities followed
during six months externship at three zoological institutions in the United States of America.
These externships were performed in order to conclude the sixth and last year of the
integrated master in veterinary medicine of the University of Evora, with the main goal of
obtaining more knowledge and experience in this area of the veterinary field. From the more
varied number of species, to the more complex procedure, by exemplification with a case of
preventative medicine in a western lowland gorilla (Gorilla gorilla gorilla), this report
provides information about some of the most important and/or interesting aspects of
zoological medicine; Resumo:
Medicina das Especies Zoologicas
Relatório de estágio produzido com o intuito de descrever e dar a conhecer as
actividades seguidas e realizadas durante seis meses de estágio em três entidades zoológicas
nos Estados Unidos da América. Estes estágios foram realizados de forma a concluir o sexto
e último ano do ciclo de estudos do mestrado integrado em medicina veterinária da
Universidade de Évora, com o objectivo principal de obter maior conhecimento e experiência
nesta área do ramo veterinário. Desde o mais variado número de espécies, até ao
procedimento mais complexo, atraves da exemplificacao com um caso de medicina
preventiva num gorila-do-ocidente (Gorilla gorilla gorilla), este relatório fornece
informação sobre alguns dos aspectos mais importantes e/ou interessantes da medicina
zoológica.
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Rash, Mickey Ellen. "Veterinary technician assistant curriculum guideline." CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1930.
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The purpose of this thesis was to develop a core curriculum to be presented to the state for consideration as the established curriculum guideline for veterinary technician assistants/veterinary assistant programs.
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Vinten, Claire. "The development of clinical reasoning in veterinary students." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33728/.
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Clinical reasoning is the skill used when veterinary surgeons make a decision regarding the diagnosis, treatment plan or prognosis of a patient. Despite its necessity and ubiquity within clinical practice, very little is known about the development of clinical reasoning during undergraduate training. Even less is understood about how veterinary schools should be helping students improve this skill. The aim of the research presented within this thesis was to, firstly, examine the development of clinical reasoning ability within veterinary students and, secondly, to investigate possible methods to aid this process. The University of Nottingham School of Veterinary Medicine and Science (SVMS) was used as a case study for this research. In study one, focus groups and interviews were conducted with SVMS staff, students and graduates to investigate the development of clinical reasoning. A curriculum document content analysis was also performed. The findings suggested that clinical reasoning development is not optimal, with alumni facing a steep learning curve when entering practice. These results were used to design study two, in which a simulated consultation exercise utilizing standardised clients was created and implemented for final year students. The success of the simulation was measured using both quantitative and qualitative methods – all of which supported the use of the session for clinical reasoning development. The final study, also building on the findings of study one, aimed to improve the accessibility of veterinary surgeons’ decision-making processes during student clinical extramural studies placements (CEMS). A reflective Decision Diary was created and trialled with third and fourth year SVMS students. Diary content analysis showed the study aim was met, triangulated by survey and focus group findings. During the research, wider issues relating to clinical reasoning integration into veterinary curricula were unearthed. These included low student awareness of the subject and the misalignment between the skill learnt during training and the skill required when in practice. Several recommendations have been made to improve the design of the undergraduate curriculum in relation to clinical reasoning.
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Hardin, Laura E. "The problem-solving process of veterinary students /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3012974.
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Byington, Tori C. "Post-DVM educational intentions among third-year veterinary medical students : a hierarchical analysis of mentoring, gender, and organizational context." Online access for everyone, 2006. http://www.dissertations.wsu.edu/Dissertations/Spring2006/t%5Fbyington%5F042606.pdf.
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Wolter, Matthias. "Regional Stormwater Management Facility System at the School of Veterinary Medicine, Blacksburg, Virginia." Master's thesis, Virginia Tech, 1996. http://hdl.handle.net/10919/30556.
Full textAbstract:
Continuing development of the Virginia Tech campus is increasing downstream flooding and water quality problems. To address these problems, the University has proposed the construction of a stormwater management facility to control the quantity and quality of stormwater releases to Strouble Creek, a tributary of the New River.
The overall goal of this project is to design a stormwater management facility proposed for the Virginia-Maryland College of Veterinary Medicine at Virginia Tech in Blacksburg, Virginia that will reduce present and anticipated downstream flooding and water quality problems.
Specific objectives of the project are:
* control of flooding in lower areas by reducing the peak discharge while disturbing existing wetlands as little as possible,
* address removal of major NPS pollutants such as total phosphorus (TP), total nitrogen (TN), metals, organic compounds related to petroleum and gasoline, and suspended sediment (SS) from stormwater runoff, and
* design of a dam system that is able to withstand all driving forces and constructed in accordance with governing regulations.
The design requirement to limit wetland disturbance below one acre was maintained. The requirement set by officials of Virginia Tech is based on the Nationwide Permit 26 of the Wetland Regulations. An individual permit process is thus avoided. Considering this demand, however, the freedom of the stormwater management facility design was significantly restricted. Resulting from the previous restrictions mentioned, the facility will include two ponds in series - a lower, dry pond and an upper, wet pond. The stormwater management system is designed to reduce the peak discharge. The dry pond is designed to detain water only for a short period of time, as opposed to the wet pond which is designed to retain water, thereby maintaining a permanent pool of water, and to change the characteristics of runoff.
The wet pond was chosen to be of an Extended Detention wetland type. Aspects such as the availability of suitable area and detention volume governed the decision to make use of this type of stormwater wetland. The constraint on a maximum possible water surface elevation due to the Veterinary School1s road embankment, which crest elevation is at 2023 ft, was considered in the design.
The stormwater management facility was designed to meet water quantity control requirements and to address water quality benefits. Storm water management regulations intending to mitigate the adverse effects of land development to streams and waterways were met. Requirements to limit peak discharges from 2-year and 10-year events to existing discharge levels were achieved.
Several outlet structures for each of the ponds were investigated. The structures proposed are a perforated riser/broad-crested weir for the wet pond and a proportional weir for the dry pond. They were chosen as a result of analyses on hydraulic performance, maximum water surface elevations, drawdown times, peak discharge rates, and pollutant removal capabilities.
The average pollutant removal capability of 75% of TSS, 45% TP, and 25% TN for an extended stormwater wetland, as found in the literature, is expected to be lower for the proposed facility, since the wetland-to-watershed-area ratio is considerably smaller (0.22%) than the required minimum ratio of 1%. However, other suggested desirable parameter for extended detention wetland systems such as required treatment volume, effective flow path length, and dry weather water balance will be maintained.
The structural design of the dams was based on experience and research data. The dams are designed to consist of two zones, shell and core. The core extends as a cutoff trench 4 feet below the ground surface. Additionally, toe drain trenches and anti-seep collars along the pipe where penetrating the dam will be placed to collect and reduce seepage, respectively. Special considerations toward seepage problems were taken into account for both dams by placing a cutoff trench and a toe drain trench.
Note: The appendix of this project report contains four AutoCAD files, that can only be viewed using AutoCAD.Master of Engineering
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Cipolla, M. "ONE COMMUNICATION AND ONE HEALTH: COMMUNICATION IN VETERINARY MEDICINE TO IMPROVE HUMAN HEALTH." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/232569.
Full textAbstract:
Health communication has become recently an essential and powerful tool for public health. Its role has been largely recognized in human medicine, but it has been less considered in veterinary medicine even if this latter field is not less decisive for the human health. The One Health concept unified the two medicines recognizing that human health is inextricably connected to animal health and environment.
Within this framework, we design this study to investigate the relationship between health communication and One Health. Particularly, we focused on the role of communication in veterinary medicine and how it has the potential to improve human health.
Veterinary medicine competences include a broad spectrum of aspects, which can’t be covered in a single study. Moreover, we were interested in investigate if communication has a role also in the veterinary areas traditionally considered less linked to public health. Therefore, this study was focused on clinical communication, both in companion and in food-producing animals practice.
This study confirmed the outcomes from previous surveys and showed the importance of communication in veterinary medicine in improving human health.
Communication in veterinary medicine is not less important for human health, and is not different from what is usually considered health communication. Indeed, both of them cover the same issue (zoonoses, food safety etc.) and use the same strategies.
Therefore, a “One Communication” approach appear to be the most helpful tool in improving human health in the One World-One Health-One Medicine.
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Chappell, Colin Graham. "Multidimensional liquid and gas chromatographic methods for veterinary drug analysis." Thesis, University of East Anglia, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357971.
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Sheridan, Fallon Bliss. "A STUDY TO DETERMINE STUDENT PERCEPTIONS OF THE CAL POL VETERINARY CLINIC." DigitalCommons@CalPoly, 2014. https://digitalcommons.calpoly.edu/theses/1282.
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The purpose of this study was to determine the important benefits of Cal Poly Veterinary Clinic (CPVC) and establish areas of interest for the students at the CPVC. The CPVC is a student run veterinary clinic that exposes students to teachable hands-on veterinary experiences by addressing the needs of animals on campus as well as animals in the San Luis Obispo.
This study thoroughly investigated the student who have taken or are currently taking any of the five courses taught at the CPVC. The research was accomplished through a survey questionnaire. The student questionnaire was conducted by the researcher at Cal Poly-SLO and was administered during the spring quarter of 2014. The analysis identified that hands-on learning experiences were most valued by students at the CPVC. A mission statement for the CPVC was also development for a better understanding of the clinic as a whole for the Cal Poly students, faculty, and San Luis Obispo community.
The survey results have determined the preferences of the students with regards to interest in certain clinical experiences which included anesthetic surgery along with students preferred interest in animal species- small animals. The survey results also provided the CPVC with data regarding the importance of difference benefits of the CPVC offered to student and the student satisfaction level of different factors of the CPVC. This information will help the Animal Science Department at Cal Poly by enhancing the needs of the students in the program and preparing future veterinary medical students with necessary skill sets.
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Bailey, Thomas Andrew. "Disease, therapeutics and preventive medicine in avian captive breeding programmes : the example of the houbara bustard, Chlamydotis undulata." Thesis, University of Kent, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297354.
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Masoko, Peter. "Characterization of antifungal compounds isolated from Combretum and Terminalia species (Combretaceae)." Thesis, Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-07102007-115218.
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Saluja, Patricia Gail. "Vetting the vets : the regulation of the veterinary profession in the UK." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=158484.
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This thesis investigates the regulation of the veterinary profession in the UK. In the UK this profession is regulated by the Royal College of Veterinary Surgeons (RCVS) under the Veterinary Surgeons Act 1966 (VSA 1966). Since that date there have occurred vast changes in veterinary medicine and science and the delivery of veterinary services, legal developments in other areas, including professional regulatory law, and societal changes in attitudes towards animals and expectations of the professions. This research was undertaken in order to determine whether the regulatory system for the veterinary profession in the UK is well designed to achieve the aims appropriate to the present-day profession, and to propose reforms where these are indicated. The system was evaluated by applying a set of benchmark criteria used by the National Health Service Ombudsman for England whose jurisdiction encompasses clinical as well as administrative matters. The study shows that the current system is well suited to functions such as regulating and monitoring veterinary education and rule-making for the control of animal diseases and zoonoses. However, the overall conclusion is that the VSA 1966 is outdated and should be replaced by new legislation. Arguments are made in favour of the following key reforms: separation of regulatory role from Royal College functions; changes in the composition of the regulatory body; introduction of the regulation of paraprofessionals and veterinary practices; plus a range of changes across the disciplinary system involving revision of the grounds and sanctions for disciplinary action, clarification of the identity of the regulator, reforms in the investigation of complaints, disciplinary hearings, appeals and the position of the complainant in the disciplinary process. Whilst some improvements could be made under the current regime, the view remains that new legislation is needed. Although it appears that the RCVS is in favour of this, the necessary political will seems to be lacking on the part of government.
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Streit, Timothy Michael. "KINETIC STUDY OF THE SIDE-DOOR MUTANTS OF THE MODEL CARBOXYLESTERASE PNB CE." MSSTATE, 2007. http://sun.library.msstate.edu/ETD-db/theses/available/etd-06212007-134428/.
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Carboxylesterases (CEs) metabolize a wide range of endogenous compounds and xenobiotics containing ester bonds. Crystal structures of mammalian CEs indicate a ?side door? located adjacent to the catalytic gorge that may act as an alternative pore for the trafficking of substrates and products. This study investigated the role of the ?gate? residue of the side door during para-Nitrobenzyl esterase (pnb CE)-catalyzed hydrolysis of esters. Purified recombinant pnb CE proteins were examined for their hydrolytic activity toward several esters. Mutation of the gate residue altered the kinetic parameters of pnb CE toward these substrates, demonstrated by increased Km values and decreased Vmax values. Site-specific mutations of the ?gate? residue also affected the sensitivity of the enzyme toward inhibiting organophosphate compounds. A distinct possibility is that the side door mutants affect substrate hydrolysis by increasing the steric hindrance and/or electrostatic repulsion between the substrate and the active site catalytic residues.
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Wan, Xiufeng. "AN AMINOPEPTIDASE ACTING AS A POTENTIAL FACTOR IN HOST ADAPTATION OF MYCOPLASMA GALLINARUM." MSSTATE, 2002. http://sun.library.msstate.edu/ETD-db/theses/available/etd-06242002-150613/.
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Unlike most other host-specific mycoplasmas, Mycoplasma gallinarum exists as a commensal with a host range including most poultry as well as some mammals. This property of M. gallinarum may reflect unique mechanisms for its colonization and persistence in hosts. Whereas M. gallinarum shows leucine and arginine aminopeptidase activity, the genes encoding the enzymes had not been cloned and characterized. We identified an aminopeptidase gene (APN) by oligonucleotide hybridization to a genomic library of M. gallinarum in lambda ZAPII bacteriophage. Nucleotide sequence analysis of overlapping phage clones identified a 1,362 bp open reading frame (ORF) encoding a putative leucine aminopeptidase gene. Database searches indicate that this ORF has 68% nucleotide identity and 51% amino acid identity with the M. salivarium leucine aminopeptidase gene. The active sites of the leucine aminopeptidases in other eukaryotes and prokaryotes were conserved in the cloned aminopeptidase gene. Northern-blot hybridization analysis showed that this ORF is expressed as a 1.5 kb transcript. Southern-blot hybridization analysis demonstrated this gene was present as a single copy in M. gallinarum. Characterization of the leucine aminopeptidase demonstrated that it is a metallo-aminopeptidase (EC 3.4.11.1) and is located in the cytoplasm with a weak interaction with the cell membrane. The subcellular location was further confirmed by immunoblotting with polyclonal anti-recombinant APN serum and M. gallinarum Triton-114 partitions. Immunoblotting results with sera from three chickens experimentally infected with M. gallinarum showed that there were very few proteins in M. gallinarum exposed to the host immune responses and that leucine aminopeptidase was not able to stimulate production of specific humoral antibody. Our results suggest that this leucine aminopeptidase play a role in nutrition supply for the host adaptation of M. gallinarum and that the enzyme was not strongly immunogenic.
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Horstman, Christopher Larry. "BIOMECHANICAL AND METABOLIC CHANGES WITHIN RABBIT ARTICULAR CARTILAGE FOLLOWING TREATMENT WITH RADIOFREQUENCY ENERGY." MSSTATE, 2005. http://sun.library.msstate.edu/ETD-db/theses/available/etd-11112005-081324/.
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The effects caused to articular cartilage by the remote use of arthroscopically-delivered RF energy to soft tissues in the joint are unknown. This investigation reported the short and long-term effects of bRF and mRF energy on the biomechanical properties and metabolic activity of articular cartilage. In addition, the effect of Cosequin® therapy was addressed. Thirty New Zealand white rabbits were randomly assigned to one of two treatment groups (Group 1 - placebo; Group 2 - Cosequin®). Histopathology, cell viability, GAG synthesis, and mechanical function of the articular cartilage were compared between groups. Data were analyzed using a mixed model ANOVA (p=0.05). Immediate chondrocyte death was created by both RF devices. This damage was noted to be superficial and did not lead to the progressive deterioration of the extracellular matrix or mechanical function of the articular cartilage. Cosequin® therapy was unable to demonstrate significant differences compared to the control group.
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Hawkins, Stacey M. "Opportunities and occupations in animal and veterinary sciences based on the current careers of West Virginia University alumni." Morgantown, W. Va. : [West Virginia University Libraries], 2002. http://etd.wvu.edu/templates/showETD.cfm?recnum=2671.
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Thesis (M.S.)--West Virginia University, 2002.Title from document title page. Document formatted into pages; contains viii, 57 p. Vita. Includes abstract. Includes bibliographical references (p. 44).
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Hill, John Russell. "An investigation of the role of preventive medicine in the improvement of productivity in the pig industry of the United Kingdom." Thesis, Royal Veterinary College (University of London), 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284206.
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Knox, Kathryn M. G. "Statistical interpretation of a veterinary hospital database : from data to decision support." Thesis, University of Glasgow, 1998. http://theses.gla.ac.uk/6735/.
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Research was undertaken to investigate whether data maintained within a veterinary hospital database could be exploited such that important medical information could be realised. At the University of Glasgow Veterinary School (GUVS), a computerised hospital database system, which had maintained biochemistry and pathology data for a number of years, was upgraded and expanded to enable recording of signalment, historical and clinical data for referral cases. Following familiarisation with the computerised database, clinical diagnosis and biochemistry data pertaining to 740 equine cases were extracted. Graphical presentation of the results obtained for each of 18 biochemistry parameters investigated indicated that the distributions of the data were variable. This had important implications with respect to the statistical techniques which were subsequently applied, and also to the appropriateness of the reference range method currently used for interpretation of clinical biochemistry data. A percentile analysis was performed for each of the biochemistry parameters; data were grouped into ten appropriate percentile band intervals; and the corresponding diagnoses tabulated and ranked according to frequency. Adoption of a Bayesian method enabled determination of how many times more likely a diagnosis was than before the biochemistry parameter concentration had been ascertained. The likelihood ratio was termed the "Biochemical Factor". Consequently, a measurement on a parameter, such as urea, could be classified on the percentile scale, and a diagnosis, such as hepatopathy, judged to be less or many times more likely, based on the numerical evaluation of the Biochemical Factor. One issue associated with the interrogation of the equine cases was that the diagnoses were clinical in origin, and, because they may have been made with the assistance of biochemistry data, this may have yielded biased results. Although this was considered unlikely to have affected the findings to a large extent, a database containing biochemistry and post mortem diagnosis data for cattle was also assessed.
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Kshirsagar, Shukla. "Economic impacts of the Virginia-Maryland Regional College of Veterinary Medicine on the Commonwealth of Virginia." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-05022009-040712/.
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Guthrie, Wendy. "Keeping clients in line : a grounded theory explaining how veterinary surgeons control their clients." Thesis, University of Strathclyde, 2000. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21125.
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This thesis explains how veterinary surgeons keep their clients in line through a melange of fact and fiction. Originating from the intimate study of veterinary interactions, it represents theory systematically grounded in data. Veterinarians employ mystification processes to manipulate clients' awareness. Vets engage in coaching clients to suit their own agendas. These activities may be benign or opportunistic. Cultivating strategies are also explained whereby vets seek apparently friendly relationships with clients. This disguises the instrumental nature of these interactions. The research indicates that keeping people in line is a robust process evident in diverse contexts. It has obvious commercial significance and is likely to be of relevance to veterinarians, their clients, marketers, researchers and potentially to those wishing to control others in diverse contexts.
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Lincoln, Anne E. "A supply-side approach to occupational feminization veterinary medicine in the United States, 1976-1995 /." Online access for everyone, 2004. http://www.dissertations.wsu.edu/Dissertations/Spring2004/A%5FLincoln%5F050404.pdf.
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Done, Stanley Herbert. "Climate, aerial pollution and pneumonia in a pig finishing house." Thesis, Royal Veterinary College (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309249.
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McCarthy, Helen Elizabeth. "A case-control study to investigate risk factors for equine grass sickness with a particular reference to the role of Clostridium botulinum." Thesis, University of Liverpool, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250565.
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Luke, Cliff J. "In vitro characterisation of the protease, VP4 in infectious bursal disease virus." Thesis, University of Surrey, 1998. http://epubs.surrey.ac.uk/843479/.
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Infectious bursal disease virus (IBDV) is a member of the birnavirus family and is the causative agent of infectious bursal disease (IBD). The virus has a bisegmented dsRNA genome; the larger of these 2 segments is segment A and has 3 open reading frames (ORFs). One of these ORFs encodes a polyprotein that is processed to 3 polypeptides VPX, VP3, and VP4. VP4 has been demonstrated to be responsible for the cleavage of the polyprotein in an autocatalytic co-translational manner. The VP4 protein has not yet been characterised and has no homology with any other known protease except a limited homology with the Lon protease in bacteria. Several active sites are proposed; with the spacing of type I serine proteases, with spacing of type II serine proteases and with spacing of the beta-lactamase family of proteases. The cleavage sites have been proposed by molecular weight determination as being 2 dibasic residues at either end of VP4. Here I describe the expression of the full length polyprotein in a coupled transcription/translation system and in E. coli. Deletion mutagenesis of the VP4 revealed that VP4 is required for correct processing of the processing of VP3 and the processing of VPX to VP2. However, the processing of VP3 is only completely abolished when a deletion into VP3 passed the A-x-AAS cleavage site. Deletion mutagenesis of the N terminus of VP3 in the polyprotein showed that the cleavage sites of VP4 as being A-x-AAS sequences. Site directed mutagenesis studies within VP4 revealed several important residues for the correct processing, the most important of these being the S652. Of the residues mutated here, there does not seem to be a "classical" catalytic triad for this protease.
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Collins, Alison Jane. "Ontogeny of lactase-phlorizin hydrolase in the pig small intestine." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388687.
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Wilkes, Margaret. "Clinical and morphological investigations into inner ear disease in the dog with special reference to deafness and vestibular deficit in the Doberman." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385502.
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Otter, Arthur. "A study of the neuropathogenesis of listerial encephalitis." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359880.
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Da, Costa Ana P. C. "Neurohumoral control of maternal behaviour in sheep." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360634.
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Horsburgh, Brian Colin. "Molecular studies of canine coronvirus." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240988.
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Littlewood, Janet Denise. "Factor VIII - phospholipid mixtures and factor VIII inhibitors : studies in haemophilic dogs." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278069.
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