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Journal articles on the topic 'Verapamil'

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Author: Grafiati

Published: 4 June 2021

Last updated: 26 February 2023

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1

Vukovic-Ercegovic, Gordana, Natasa Perkovic-Vukcevic, Snezana Djordjevic, Zoran Segrt, Olivera Potrebic, Snezana Jankovic, Jasmina Jovic-Stosic, and Nadica Marinkovic. "Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report." Vojnosanitetski pregled 74, no. 3 (2017): 278–81. http://dx.doi.org/10.2298/vsp150901010v.

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Introduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complete heart block. Because of the applied standard therapy failure and further patients impairment, Intralipid? 20% was used. Sinus rhythm was restored, arterial blood pressure increased and verapamile concentrations, both total and free decreased. Conclusion. Intravenous lipid emulsion can be important in treatment of severe acute intoxication and cardiotoxicity caused by verapamil.

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2

Cartee, G. D., C. Briggs-Tung, and J. O. Holloszy. "Diverse effects of calcium channel blockers on skeletal muscle glucose transport." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 263, no. 1 (July 1, 1992): R70—R75. http://dx.doi.org/10.1152/ajpregu.1992.263.1.r70.

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Verapamil, a calcium channel blocker, inhibited the insulin-stimulated glucose transport rate in isolated rat epitrochlearis muscle in a dose-dependent manner (1-200 microM) without affecting basal glucose transport rate. Verapamil's inhibition was rapid in onset and disappearance; changes in glucose transport rate were detectable when verapamil was added to or removed from the incubation medium 15 min prior to measurement of glucose transport. Verapamil also inhibited the stimulation of muscle glucose transport caused by hypoxia, indicating that the effect was not limited to insulin action. Although the optical isomers of verapamil vary considerably in their potency as Ca2+ channel blockers, they were equally effective inhibitors of insulin-stimulated glucose transport rate. Nifedipine (10-200 microM), a more potent blocker of skeletal muscle Ca2+ channels than verapamil, was less effective as an inhibitor of insulin-stimulated glucose transport. Furthermore, nifedipine (10 microM) did not inhibit hypoxia-stimulated glucose transport. Diltiazem (200 microM), another Ca2+ channel blocker, did not reduce insulin-stimulated glucose transport.

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3

Boyer, Allison Jo, Rachael Erin Ketcham, Clint Allen Hostetler, Jeffrey Paul Orlowski, and Ronald A. Squires. "Performance of Renal Allografts Perfused With Verapamil-Treated Perfusion Solution." Progress in Transplantation 31, no. 4 (October 29, 2021): 373–80. http://dx.doi.org/10.1177/15269248211045999.

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Verapamil has been used in perfusion solution to improve kidney performance, but evidence was anecdotal, and no research has been reported on recipient outcomes. Our organization began a program to evaluate Verapamil’s effect on pump performance, transplant rate, and recipient outcomes. One kidney in a pair was treated with Verapamil and one with standard perfusion. Donor inclusion criteria were age 18 or older and both kidneys were placed on the pump. The laterality of the treated kidney was changed every month to reduce bias. From January 1, 2020 to June 30, 2020, 88 kidneys were evaluated. Of those, 21 donors had both kidneys transplanted to different recipients, so for those 42 kidneys, recipient outcomes were evaluated. Small improvements in pump performance were observed in the Verapamil-treated kidneys and more were transplanted. No clinical differences were found in recipients between the Verapamil-treated and standard perfused kidneys. A larger cohort is needed to determine whether differences are significant.

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4

&NA;. "Verapamil see Lithium/verapamil." Reactions Weekly &NA;, no. 290 (March 1990): 8. http://dx.doi.org/10.2165/00128415-199002900-00042.

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5

Gowarty, Jasmine L., and Jon D. Herrington. "Verapamil as a culprit of palbociclib toxicity." Journal of Oncology Pharmacy Practice 25, no. 3 (March 9, 2018): 743–46. http://dx.doi.org/10.1177/1078155218761798.

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A promising drug, palbociclib, received accelerated approval as a first line treatment when used with the aromatase inhibitor, letrozole, for postmenopausal women with hormone receptor positive advanced or metastatic breast cancer. We report a case of a patient who presented with febrile neutropenia, grade 3 stomatitis with lip swelling, periorbital edema, and transaminitis while on palbociclib and verapamil. Labs normalized upon discontinuation of verapamil and our patient was able to continue treatment with palbociclib and letrozole. Verapamil’s inhibition of both permeability-glycoprotein (P-gp) and CYP3A4 is suspected to have led to the adverse side effects seen in our patient.

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6

&NA;. "Verapamil see Diltiazem/nifedipine/verapamil." Reactions Weekly &NA;, no. 310 (July 1990): 12. http://dx.doi.org/10.2165/00128415-199003100-00068.

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7

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1382 (December 2011): 34. http://dx.doi.org/10.2165/00128415-201113820-00125.

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8

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1183 (January 2008): 30. http://dx.doi.org/10.2165/00128415-200811830-00096.

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9

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1153 (May 2007): 26. http://dx.doi.org/10.2165/00128415-200711530-00086.

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10

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1158 (June 2007): 27. http://dx.doi.org/10.2165/00128415-200711580-00077.

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11

&NA;. "Verapamil." Inpharma Weekly &NA;, no. 1158 (October 1998): 17. http://dx.doi.org/10.2165/00128413-199811580-00030.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 1360 (July 2011): 36. http://dx.doi.org/10.2165/00128415-201113600-00123.

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13

&NA;. "Verapamil." Reactions Weekly &NA;, no. 537 (February 1995): 12. http://dx.doi.org/10.2165/00128415-199505370-00043.

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14

&NA;. "Verapamil." Reactions Weekly &NA;, no. 576 (November 1995): 12. http://dx.doi.org/10.2165/00128415-199505760-00042.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 577 (November 1995): 12. http://dx.doi.org/10.2165/00128415-199505770-00044.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 596 (April 1996): 12. http://dx.doi.org/10.2165/00128415-199605960-00043.

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17

&NA;. "Verapamil." Reactions Weekly &NA;, no. 437 (February 1993): 12. http://dx.doi.org/10.2165/00128415-199304370-00050.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 450 (May 1993): 15. http://dx.doi.org/10.2165/00128415-199304500-00075.

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19

&NA;. "Verapamil." Reactions Weekly &NA;, no. 458 (July 1993): 12. http://dx.doi.org/10.2165/00128415-199304580-00063.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 459 (July 1993): 12. http://dx.doi.org/10.2165/00128415-199304590-00064.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 469 (September 1993): 12. http://dx.doi.org/10.2165/00128415-199304690-00059.

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22

McTavish, Donna, and Eugene M. Sorkin. "Verapamil." Drugs 38, no. 1 (July 1989): 19–76. http://dx.doi.org/10.2165/00003495-198938010-00003.

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23

Brogden, Rex N., and Paul Benfield. "Verapamil." Drugs 51, no. 5 (May 1996): 792–819. http://dx.doi.org/10.2165/00003495-199651050-00007.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 616 (August 1996): 12. http://dx.doi.org/10.2165/00128415-199606160-00041.

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25

&NA;. "Verapamil." Reactions Weekly &NA;, no. 654 (June 1997): 12. http://dx.doi.org/10.2165/00128415-199706540-00037.

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26

&NA;. "Verapamil." Reactions Weekly &NA;, no. 845 (March 2001): 11–12. http://dx.doi.org/10.2165/00128415-200108450-00025.

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27

&NA;. "Verapamil." Reactions Weekly &NA;, no. 850 (May 2001): 11. http://dx.doi.org/10.2165/00128415-200108500-00030.

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28

&NA;. "Verapamil." Reactions Weekly &NA;, no. 375 (November 1991): 12. http://dx.doi.org/10.2165/00128415-199103750-00077.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 377 (November 1991): 12. http://dx.doi.org/10.2165/00128415-199103770-00060.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 379 (November 1991): 12. http://dx.doi.org/10.2165/00128415-199103790-00068.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 383 (January 1992): 12. http://dx.doi.org/10.2165/00128415-199203830-00073.

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32

&NA;. "Verapamil." Reactions Weekly &NA;, no. 404 (June 1992): 12. http://dx.doi.org/10.2165/00128415-199204040-00054.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 407 (June 1992): 12. http://dx.doi.org/10.2165/00128415-199204070-00048.

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34

&NA;. "Verapamil." Reactions Weekly &NA;, no. 414 (August 1992): 12. http://dx.doi.org/10.2165/00128415-199204140-00051.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 415 (August 1992): 12. http://dx.doi.org/10.2165/00128415-199204150-00064.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 418 (September 1992): 12. http://dx.doi.org/10.2165/00128415-199204180-00055.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 423 (October 1992): 12. http://dx.doi.org/10.2165/00128415-199204230-00053.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 1199 (April 2008): 46. http://dx.doi.org/10.2165/00128415-200811990-00139.

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39

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1091 (March 2006): 22. http://dx.doi.org/10.2165/00128415-200610910-00064.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 918 (September 2002): 11. http://dx.doi.org/10.2165/00128415-200209180-00040.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 290 (March 1990): 8. http://dx.doi.org/10.2165/00128415-199002900-00041.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 318 (September 1990): 11. http://dx.doi.org/10.2165/00128415-199003180-00060.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 326 (November 1990): 11. http://dx.doi.org/10.2165/00128415-199003260-00059.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 341 (March 1991): 12. http://dx.doi.org/10.2165/00128415-199103410-00074.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 346 (April 1991): 12. http://dx.doi.org/10.2165/00128415-199103460-00055.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 353 (June 1991): 8. http://dx.doi.org/10.2165/00128415-199103530-00047.

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&NA;. "Verapamil." Reactions Weekly &NA;, no. 355 (June 1991): 12. http://dx.doi.org/10.2165/00128415-199103550-00073.

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48

&NA;. "Verapamil." Reactions Weekly &NA;, no. 363 (August 1991): 8. http://dx.doi.org/10.2165/00128415-199103630-00044.

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49

&NA;. "Verapamil." Reactions Weekly &NA;, no. 959 (July 2003): 15. http://dx.doi.org/10.2165/00128415-200309590-00057.

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50

&NA;. "Verapamil." Reactions Weekly &NA;, no. 1294 (March 2010): 37–38. http://dx.doi.org/10.2165/00128415-201012940-00111.

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