Academic literature on the topic 'Ventricular arrhythmia storm'

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Journal articles on the topic "Ventricular arrhythmia storm"

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Magdi, Mohamed, Mahmood Mubasher, Hakam Alzaeem, and Tahir Hamid. "Resistant Ventricular Arrhythmia and the Role of Overdrive Pacing in the Suppression of the Electrical Storm." Case Reports in Cardiology 2019 (May 22, 2019): 1–4. http://dx.doi.org/10.1155/2019/6592927.

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Ventricular arrhythmia storm is a state of cardiac instability characterized by multiple ventricular arrhythmias or multiple ICD therapies within a 24-hour duration. Management of this life-threatening state depends on the reversal of the cause besides either electrical or medical management of the arrhythmia. We report a case of a 54-year-old male who underwent a percutaneous coronary intervention following massive acute myocardial infarction. Afterwards, he developed frequent life-threatening ventricular arrhythmias that required multiple shocks and antiarrhythmic medications. Despite all these interventions, it was very difficult to control the electrical instability, but after overdrive ventricular pacing, the storm subsided and within a few days the case was stabilized. Overdrive pacing is an easy temporary modality to control the resistant arrhythmia following myocardial infarction.
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Pappone, Carlo, Gabriele Negro, and Giuseppe Ciconte. "Ventricular fibrillation ablation in cardiomyopathies and arrhythmic storm." European Heart Journal Supplements 23, Supplement_E (October 1, 2021): E112—E117. http://dx.doi.org/10.1093/eurheartj/suab104.

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Abstract Sudden cardiac death (SCD) is a relevant contributor to cardiovascular mortality, often occurring as a dramatic event. It can be the consequence of a ventricular tachycardia/fibrillation (VT/VF), a common and life-threatening arrhythmia. The underlying mechanisms of this catastrophic arrhythmia are poorly known. In fact, it can occur in the presence of a structural heart condition which itself generates the suitable substrate for this arrhythmia. Nevertheless, a VF may cause SCD also in young and otherwise healthy individuals, without overt structural abnormalities, generating difficulties in the screening and prevention of these patients. The implantable cardioverter-defibrillator represents the only therapy to contrast SCD by treating a VT/VF; however, it cannot prevent the occurrence of such arrhythmias. Catheter ablation is emerging as an essential therapeutic tool in the management of patients experiencing ventricular arrhythmias.
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Vicent, Lourdes, Miriam Juárez, Irene Martín, Jorge García, Hugo González-Saldívar, Vanesa Bruña, Carolina Devesa, Iago Sousa-Casasnovas, Francisco Fernández-Avilés, and Manuel Martínez-Sellés. "Ventricular Arrhythmic Storm after Initiating Sacubitril/Valsartan." Cardiology 139, no. 2 (2018): 119–23. http://dx.doi.org/10.1159/000486410.

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Objectives: Sacubitril/valsartan was approved recently for the treatment of patients with heart failure and reduced ejection fraction. We present 6 cases of ventricular arrhythmia, that occurred shortly after sacubitril/valsartan initiation, that required drug withdrawal. Other potential triggering factors of electrical storm were ruled out and, from the arrhythmic perspective, all of the patients were stable in the previous year. Our aim is to describe the possible association of sacubitril/valsartan with arrhythmic storm. Methods: This was an observational monocentric study performed in the first 7 months of sacubitril/valsartan commercialization in Spain (October 2016). All patients were included in the SUMA (Sacubitril/Varsartan Usado Ambulatoriamente en Madrid [Sacubitril/Valsartan Used in Outpatients in Madrid]) registry. Patients were consecutively enrolled on the day they started the drug. Ventricular arrhythmic storm was defined as ≥2 episodes of sustained ventricular arrhythmia or defibrillator therapy application in 24 h. Results: From 108 patients who received the drug, 6 presented with ventricular arrhythmic storm (5.6%). Baseline characteristics were similar in the patients with and without ventricular arrhythmic storm. The total number of days that sacubitril/valsartan was administered to each patient was 5, 6, 44 (8 since titration), 84, 93, and 136 (105 since titration), respectively. Conclusions: Our data are not enough to infer a cause-and-effect relationship. Further investigations regarding a potential proarrhythmic effect of sacubitril/valsartan are probably needed.
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Wong, Bethany, Lavanya Saiva, John Buckley, and Joseph Galvin. "A first case report of dapsone inducing recurrent ventricular arrhythmia." European Heart Journal - Case Reports 3, no. 4 (September 20, 2019): 1–6. http://dx.doi.org/10.1093/ehjcr/ytz158.

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Abstract Background Ventricular arrhythmias (VAs) are life-threatening arrhythmias which are associated with significant morbidity and mortality. Ventricular arrhythmias are induced by a change in the myocardial environment altering cardiomyocyte electrophysiology. The substrate for VA includes myocardial scar, electrolyte disturbances, and drugs altering cellular electrophysiology. Case summary Here, we present a case of a 52-year-old man with known ischaemic cardiomyopathy, presenting with VA storms secondary to dapsone, an anti-microbial used in this case for the prophylaxis of pneumocystis pneumonia. This is the first case linking dapsone to the development of VAs. Ventricular arrhythmias storm occurred towards the end of the course of anti-microbial therapy and the patient was referred for sympathectomy. However, following the end of treatment, no further VA occurred and sympathectomy was therefore avoided. Discussion The underlying mechanism for the association between dapsone treatment and VA is unclear and a prolonged QTc was not observed in our case. It is important to recognize that every drug has many physiological effects and in patients with underlying diseases whereby there is already an unfavourable environment, additional drugs can lower the threshold of triggering an arrhythmia and the result can be life-threatening. In a patient with ischaemic cardiomyopathy, where underlying substrate for VA may already exist, the introduction of dapsone could lower the threshold for development of arrhythmia.
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Sani, Huzairi, Nada Syazana Zulkufli, and Sazzli Kasim. "Malignant Ventricular Arrhythmia in a Fatal Thyroid Storm." Journal of Clinical and Health Sciences 5, no. 2 (November 1, 2020): 79. http://dx.doi.org/10.24191/jchs.v5i2.8736.

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Skoczyński, Przemysław, and Paweł Pochciał. "RECURRENT SYNCOPE AS A SYMPTOM OF ELECTRICAL STORM – CASE PRESENTATION." Emergency Medical Service 8, no. 4 (2021): 271–73. http://dx.doi.org/10.36740/emems202104111.

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Dangerous ventricular arrhythmias leading to sudden cardiac death (SCD) are some of the most diffi-cult diagnostic challenges. They are often mildly symptomatic. Their often self-limiting nature means that they are difficult to capture on ECG. A 75-year old woman with chronic heart failure due to nonis-chemic cardiomyopathy reported to the cardiology clinic for a scheduled routine follow-up of the ICD, implanted three years prior as primary prevention of SCD. The patient reported recent episodes of sud-den weakness and described the episodes as hypotension. The patient associated it with too aggressive treatment of arterial hypertension. During the visit the patient experienced one of these episodes that she had previously described. The monitoring equipment in the clinic revealed ventricular tachycardia (VT). The history of the implanted ICD revealed many similar previous episodes including 5 episodes in the last 24 hours which led to a diagnosis of electrical storm. Dangerous ventricular arrhythmias may be mildly symptomatic and they are often underestimated by the patient. Fainting, especially in situa-tions unusual for the vasovagal reflex or orthostatic hypotension, should always arouse vigilance to-wards life-threatening ventricular arrhythmia.
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Matsubara, Masaki, Tomohiro Tanaka, Akinori Wakamiya, Tamiko Tamanaha, Hisashi Makino, Tomonori Tanei, Takeshi Aiba, Kengo Kusano, and Kiminori Hosoda. "First Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy Showing Refractory Ventricular Tachycardia Induced by Thyroid Storm due to Graves’ Disease." Case Reports in Endocrinology 2022 (June 23, 2022): 1–8. http://dx.doi.org/10.1155/2022/6078148.

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A 48-year-old man who was diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) due to a plakophilin 2 gene mutation developed acute both-sided heart failure with rapid atrial fibrillation and was hospitalized. After admission, sustained ventricular tachycardia, which was refractory to antiarrhythmic agents, occurred repeatedly, and required electrical cardioversion. He was diagnosed with thyroid storm due to Graves’ disease, and treatment for hyperthyroidism was initiated. After the treatment, lethal arrhythmia did not reoccur, and biventricular heart failure ameliorated. To our best knowledge, this is the first report in English of a patient with ARVC showing refractory arrhythmia induced by thyroid storm due to Graves’ disease.
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Chihara, Ray K., Edward Y. Chan, Leonora M. Meisenbach, and Min P` KIM. "Surgical Cardiac Sympathetic Denervation for Ventricular Arrhythmias: A Systematic Review." Updates in Cardiac Electrophysiology, no. 17.1 (March 25, 2021): 24–35. http://dx.doi.org/10.14797/qiqg9041.

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Ventricular arrhythmias are potentially life-threatening disorders that are commonly treated with medications, catheter ablation and implantable cardioverter defibrillator (ICD). Adult patients who continue to be symptomatic, with frequent ventricular arrhythmia cardiac events or defibrillation from ICD despite medical treatment, are a challenging subgroup to manage. Surgical cardiac sympathetic denervation has emerged as a possible treatment option for people refractory to less invasive medical options. Recent treatment guidelines have recommended cardiac sympathectomy for ventricular tachycardia (VT) or VT/fibrillation storm refractory to antiarrhythmic medications, long QT syndrome, and catecholaminergic polymorphic VT, with much of the data pertaining to pediatric literature. However, for the adult population, the disease indications, complications, and risks of cardiac sympathectomy are less understood, as are the most effective surgical cardiac denervation techniques for this patient demographic. This systematic review navigates available literature evaluating surgical denervation disease state indications, techniques, and sympathectomy risks for medically refractory ventricular arrhythmia in the adult patient population.
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Bhar-Amato, Justine, William Davies, and Sharad Agarwal. "Ventricular Arrhythmia after Acute Myocardial Infarction: ‘The Perfect Storm’." Arrhythmia & Electrophysiology Review 6, no. 3 (2017): 134. http://dx.doi.org/10.15420/aer.2017.24.1.

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Ventricular tachyarrhythmias (VAs) commonly occur early in ischaemia, and remain a common cause of sudden death in acute MI. The thrombolysis and primary percutaneous coronary intervention era has resulted in the modification of the natural history of an infarct and subsequent VA. Presence of VA could independently influence mortality in patients recovering from MI. Appropriate risk assessment and subsequent treatment is warranted in these patients. The prevention and treatment of haemodynamically significant VA in the post-infarct period and of sudden cardiac death remote from the event remain areas of ongoing study.
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Bardyszewski, Aleksander, Jacek Kuśnierz, and Paweł Derejko. "Treatment of Electrical Storm – the Electrophysiologist’s Point of View." In a good rythm 2, no. 43 (May 24, 2017): 4–8. http://dx.doi.org/10.5604/01.3001.0010.3965.

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Electrical storm is a life-threatening condition and requires immediate treatment. In most cases ventricular arrhythmia originates from previously formed lesions in the cardiac muscle. Such patients, following the necessary initial treatment, should be forwarded to catheter ablation, which is proven to reduce arrhythmia recurrence and to improve overall morbidity. Along with the technological progress related to electroanatomical mapping the growing role of meticulous substrate mapping and modification for successful ablation is being recognized.
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Dissertations / Theses on the topic "Ventricular arrhythmia storm"

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Arya, Arash Khosrow. "Predictors of appropriate and inappropriate Therapies in Patients with implantable cardioverter-defibrillator and Structural Heart Disease." Doctoral thesis, Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-197732.

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Identifying factors associated with appropriate and inappropriate therapies in patients with implantable cardioverter-defibrillator (ICD) could help to identify those at risk and reduce the incidence of this emergency situation which has detrimental effect on mortality and morbidity in patients with ICD. These studies were designed to find the prevalence and factors associated with appropriate and inappropriate therapies in patients with ICD.
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Nayyar, Sachin. "High density mapping of ventricular scar: insights into mechanisms of ventricular tachycardia." Thesis, 2014. http://hdl.handle.net/2440/93913.

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Ventricular tachyarrhythmias related to structural heart disease are the most common cause of sudden cardiac death. Many of these occur in patients with ventricular scarring, related predominantly to coronary artery disease or dilated cardiomyopathies. These regions of scarring remodel over time with ongoing collagen turnover and do not stay stable, such that patients are often subject to repeated episodes of the arrhythmia. Ventricular scars are composed of variable regions of dense interstitial fibrosis that create conduction block, interspersed with viable myocyte channels with diminished coupling which produce substrate for circuitous slow conduction pathways that promote reentry. During sinus rhythm, these channels can be identified by the presence of late potentials and long stimulus to QRS intervals during pacing in the channel. A high density of sampling in the left ventricle allows recording of small amplitude electrograms that are of fundamental emphasis in ventricular substrate mapping. Several studies have characterized channels in patients with ventricular scar and ventricular tachycardia (VT). However, there has been no assessment on the functional characteristics of these channels and whether channels that are critical to the VT circuit differ from non-VT channels. Chapter 1 reviews literature on arrhythmic burden and epidemiology of scar related VT, its cellular mechanisms, substrate characterization, techniques of VT mapping and gaps in the current knowledge. Chapter 2 presents the high density characterization of substrate in ischemic cardiomyopathy (lCM) patients with W and compares the features of VT supporting channels with channels that do not support VT. This study showed that compared to non-VT channels, VT channels are more often located in the dense scar, longer in length, have long stimulus to QRS latencies and slower conduction velocity. Chapter 3 describes the electrogram properties in regions of VT channels, and development of a stepwise model from multiple electrogram properties to ensemble regions supporting VT(s) during sinus rhythm. It also discusses the application of Shannon entropy, a fundamental measure of information content in signals, to map VT channels in sinus rhythm. This system of ablation along with high density mapping will significantly advance VT mapping and help individualize substrate based ablation. Chapter 4 presents data on high density characterization of substrate in ICM patients with W and compares with those who do not have spontaneous VT. It showed that patients without spontaneous VT have fewer channels with shorter lengths and faster conduction, compared to VT patients. These observations partly explain the relative higher predilection of few selected surviving myocyte channels in the post infarct ventricles to sustain VT. Structural heterogeneity in the scar produces spatial and temporal disturbances in ventricular repolarization over multiple time scales. Chapter 5 evaluates the role of acute autonomic modulation on beat-to-beat QT variability in patients with heart failure with and without VT and contrasts it with patients without structural heart disease. It showed that acute pacing and humoral modulation including beta-blockade fail to bring down high repolarization instability in heart failure patients and VT. Catheter ablation is the mainstay for treatment of recurrent ventricular arrhythmias in patients with structural heart disease. Chapter 6 analyses published literature on ventricular arrhythmia storm ablation in a systematic review and meta-analysis. It showed that the interventions are safe and patients often need multiple procedures including non-radiofrequency ablation measures. Although patients who had successful ablation had good long-term outcomes, a failed procedure portended an early and high rate of mortality compared with medically managed historic controls. It raised a pertinent concern of possible harmful effects of catheter ablation in a high risk patient population. In summary, this thesis has developed innovative insights into the surviving myocyte channels in patients with ischemic cardiomyopathy. It describes a novel tool for ventricular substrate mapping that is readily applicable in the clinical laboratory. The repolarization instability is elevated in these patients and is resistant to modulation by acute beta-blocker treatment. Finally, catheter ablation is safe and should be advised in most patients with ventricular arrhythmia storm.
Thesis (Ph.D.) -- University of Adelaide, School of Medicine, 2014
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Arya, Arash Khosrow. "Predictors of appropriate and inappropriate Therapies in Patients with implantable cardioverter-defibrillator and Structural Heart Disease." Doctoral thesis, 2015. https://ul.qucosa.de/id/qucosa%3A13456.

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Identifying factors associated with appropriate and inappropriate therapies in patients with implantable cardioverter-defibrillator (ICD) could help to identify those at risk and reduce the incidence of this emergency situation which has detrimental effect on mortality and morbidity in patients with ICD. These studies were designed to find the prevalence and factors associated with appropriate and inappropriate therapies in patients with ICD.
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Book chapters on the topic "Ventricular arrhythmia storm"

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Dilling-Boer, Dagmara, Paolo Della Bella, and Francesca Baratto. "Ventricular tachyarrhythmias." In The ESC Textbook of Intensive and Acute Cardiovascular Care, edited by Marco Tubaro, Pascal Vranckx, Eric Bonnefoy-Cudraz, Susanna Price, and Christiaan Vrints, 740–54. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198849346.003.0055.

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In this chapter on diagnosis and treatment of wide complex tachycardias, we provide a systematic review of current knowledge to enable prompt differentiation between potentially lethal and non-lethal arrhythmias. The importance of documentation of the arrhythmia whenever possible is stressed, as it is vital to establish a correct diagnosis. Electrical storm is the most feared arrhythmic emergency in patients with both structural heart disease and inherited arrhythmia syndromes and a step by step approach has been extensively outlined, emphasizing early installation of general anaesthesia and mechanical ventilation, haemodynamic support and ablation therapy. Finally, the significance of ventricular arrhythmias in patients undergoing revascularization for acute coronary syndromes and in particular ST elevation myocardial infarction is discussed.
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Namboodiri, Narayanan, and SP Abhilash. "Ventricular Arrhythmia Storm: Etiology, Mechanisms and Management." In Practical Cardiac Electrophysiology, 627. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/13028_43.

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Ganz, Leonard. "Electrical storm." In ESC CardioMed, edited by Brian Olshansky, 2275–78. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0538.

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Electrical storm is a condition in which there are recurrent episodes of ventricular fibrillation or sustained and/or poorly tolerated ventricular tachycardia that occurs within a short period and requires aggressive intervention to prevent imminent mortality and other adverse outcomes. The condition may be related to precipitating factors, such as ischaemia or electrolyte disturbances, or may be part of an underlying cardiac disorder (e.g. cardiomyopathy, ischaemic heart disease, and channelopathies) that, often for uncertain reasons, culminates in recurrent episodes of life-threatening ventricular arrhythmias. Frequently, sympathetic activation plays a role in precipitating episodes. Here, electrical storm is characterized and an approach to management is discussed.
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Ganz, Leonard. "Electrical storm." In ESC CardioMed, edited by Brian Olshansky, 2275–78. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0538_update_001.

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Electrical storm is a condition in which there are recurrent episodes of ventricular fibrillation or sustained and/or poorly tolerated ventricular tachycardia that occurs within a short period and requires aggressive intervention to prevent imminent mortality and other adverse outcomes. The condition may be related to precipitating factors, such as ischaemia or electrolyte disturbances, or may be part of an underlying cardiac disorder (e.g. cardiomyopathy, ischaemic heart disease, and channelopathies) that, often for uncertain reasons, culminates in recurrent episodes of life-threatening ventricular arrhythmias. Frequently, sympathetic activation plays a role in precipitating episodes. Here, electrical storm is characterized and an approach to management is discussed.
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Reports on the topic "Ventricular arrhythmia storm"

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Shalganov, Tchavdar, Milko Stoyanov, and Vassil Traykov. Outcomes following catheter ablation for ventricular tachycardia in adult patients with structural heart disease and implantable cardioverter-defibrillator: protocol for an updated systematic review and meta-analysis of randomized studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0080.

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Review question / Objective: Does catheter ablation for scar-related monomorphic ventricular tachycardia improve outcomes (defined as any appropriate ICD therapy, appropriate ICD shocks, all-cause mortality, VT storm, cardiovascular mortality, cardiovascular hospitalizations, complications) in adult patients with ischemic or non-ischemic cardiomyopathy and implantable cardioverter-defibrillator? Condition being studied: Ventricular tachycardia in patients with structural heart disease is usually an arrhythmia using the myocardial scar as a substrate for reentry. It poses a risk of syncope and sudden cardiac death, especially in patients with reduced ejection fraction. Most antiarrhythmic drugs are of little value and their use is restricted in patients with LV systolic dysfunction. Catheter ablation is a viable option for the treatment of ventricular tachycardia. In patients with previous myocardial infarction the arrhythmogenic scar is located most frequently subendocardially and is readily accessible using endocardial approach, while in non-ischemic cardiomyopathy the scar is frequently located in the midmyocardial or subepicardial layers. This is the reason endocardial catheter ablation to be less effective in those patients and to more often necessitate epicardial approach.
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