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Academic literature on the topic 'Venereal diseases'

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Published: 4 June 2021
Last updated: 29 July 2024

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Journal articles on the topic "Venereal diseases"

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Kandela, Peter. "Venereal Diseases." Lancet 353, no. 9150 (January 1999): 419. http://dx.doi.org/10.1016/s0140-6736(05)75005-4.

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Pattman, R. "Venereal diseases." Sexually Transmitted Infections 64, no. 1 (February 1, 1988): 67. http://dx.doi.org/10.1136/sti.64.1.67.

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Franjić, Siniša. "Adolescent Venereal Diseases." Madridge Journal of Immunology 3, no. 2 (August 27, 2019): 95–99. http://dx.doi.org/10.18689/mjim-1000122.

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Doğan, Bilal, and Özlem Karabudak Abuaf. "Venereal Diseases in Children." Turkderm 45, no. 2 (December 15, 2011): 138–42. http://dx.doi.org/10.4274/turkderm.45.s24.

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P., Mamatha, Sheena Arora, and Abhijeet Vardhan. "Clinical and epidemiological study of non-venereal genital diseases in females." International Journal of Research in Dermatology 6, no. 3 (April 21, 2020): 323. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20201494.

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<p class="abstract"><strong>Background:</strong> Dermatoses which are not sexually transmitted are referred to as non-venereal dermatoses of external genitalia. Venereal and non-venereal dermatoses tend to be confused and it is associated with guilt feeling in affected patients. The aim of the study was to study the incidence of non-venereal lesions of the genitalia and to know the incidence of non-venereal lesions of the genitalia in association with dermatoses of other parts of the body.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional, clinical and observational study in 250 female patients attending dermatovenereology OPD of Vydehi Hospital, Bengaluru with non-venereal genital lesions for a period of 18 months. cases having venereal diseases were excluded from the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> The study included 250 female patients with non-venereal genital lesions. Twenty-five different types of non-venereal dermatoses were observed. Inflammatory disorders were most common accounting for 128 patients (51.2%). Among inflammatory disorders lichen simplex chronicus was seen most followed by lichen sclerosus. Candidiasis was found to be more common among infections and infestations. Vitiligo was the commonest pigmentary disorder seen in our study. Other cases noted include epidermal inclusion cyst, Bartholin cyst and fibroepithelial stromal polyp. Pre malignant conditions like Bowenoid papulosis and malignant lesions like squamous cell carcinoma are also seen.</p><p class="abstract"><strong>Conclusions:</strong> This study helps in understanding the importance of diagnosis of non-venereal dermatoses and to differentiate it from venereal causes.</p><p> </p>
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Lalević-Vasić, Bosiljka M., and Marina Jovanović. "History of dermatology and venereology in Serbia – Part IV/1: Dermatovenereology in Serbia from 1919 – 1945." Serbian Journal of Dermatology and Venerology 2, no. 1 (January 1, 2010): 26–31. http://dx.doi.org/10.2478/v10249-011-0020-1.

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Abstract After the First World War, Serbia was ravaged and in ruins, whereas the Health Care Service was destroyed. Organization and reorganization of the Health Care Service started with a fight against the spread of infectious diseases. Foundation of specialized health institutions was among the first tasks. As early as 1920, an Outpatient Service forSkin and Venereal Diseases was established and managed by Prof. Đorđe Đorđević. In 1922, after he was appointed as Associate Professor at the newly established Faculty of Medicine in Belgrade, he founded a Clinic for Skin andVenereal Diseases, and acted as its first director. In 1928, a Municipal Outpatient Clinic for Skin and Venereal Diseases was founded, whereas in 1938 a modern organization of the Service was established in a new building. After a break during the I World War, the Dermatovenereology Department of the General Military Hospital in Belgrade, founded in 1909, continued working until the Second World War. In Novi Sad, the City Hospital was founded in 1909, including a Dermatovenereology Department. After the First World War, in 1921, Dr. Jovan Nenadović founded a Department of Skinand Venereal Diseases (100 beds) in the General Public Hospital, as well as, an independent Public Outpatient Clinic for free-of-charge treatment of patients with venereal diseases. In Niš, the first Organization Unit for Venereal Diseases was founded in 1912, but the Department of Venereal Diseases was founded in 1921, and it was managed by Dr. Petar Davidović, while in 1927 a Department of Skin and Venereal Diseases was established within the General PublicHospital. In 1920, a Dermatovenereology Department of the Military Hospital in Niš was established. Apart from these, as early as 1921, there was a total of 7 Outpatient Clinics in Serbia, and in 1923 there were 14 venereal departments, and 1 dermatovenereology department.
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Miyagasheva, Surzhana B. "«Секретные» болезни у монгольских народов в начале XX в.: традиционные представления и методы лечения." Монголоведение (Монгол судлал) 15, no. 3 (December 8, 2023): 446–57. http://dx.doi.org/10.22162/2500-1523-2023-3-446-457.

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Introduction. The article examines some traditional ideas of venereal diseases traced in Mongolic cultures, reasons once believed to lie behind them, and treatment methods prescribed by folk and Tibetan medicine. Goals. The study attempts an analysis of medicinal knowledge and experiences used by Buryats and Mongolians to cure venereal diseases in the early twentieth century. Materials and methods. The work employs the comparative method and that of historical-comparative analysis. It focuses on archival collections of S. Baldaev, I. Manzhigeev, works of M. Khangalov and Ts. Jamtsarano for insights into shamanistic views and ideas pertaining to venereal diseases. The corpus of examined works on Tibetan medicine has been compiled from traditional Tibetan and Buryat-Mongolian guides to medicinal drugs and herbs — zhors. Results. The paper shows that despite mythological interpretations of venereal diseases as such did prevail, the Mongolic peoples were distinguished by a completely rational understanding of syndromes and course patterns characteristic of certain venereal diseases.
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Lalević-Vasić, Bosiljka M. "History of dermatology and venereology in Serbia - part III/1: Dermatovenereology in Serbia from 1881 - 1918." Serbian Journal of Dermatology and Venerology 1, no. 3 (August 1, 2009): 123–27. http://dx.doi.org/10.2478/v10249-011-0012-1.

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Abstract This paper deals with the period from 1881 to 1918, when the following Sanitary Laws were passed: Law on the Organization of the Sanitary Profession and Public Health Care (1881), which implemented measures for protection from venereal diseases, as well as restriction of prostitution; Public Sanitary Fund (1881), with independent budget for health care; Announcement on Free of Charge Treatment of Syphilis (1887). Dermatovenereological Departments were also founded: in the General Public Hospital in Belgrade (1881), and in the General Military Hospital (1909). The Hospital in Knjaževac for Syphilis was reopened (1881), as well as mobile and temporary hospitals for syphilis, and a network of County and Municipality hospitals. The first Serbian dermatovenereologist was Dr. Jevrem Žujović (1860 - 1944), and then Dr. Milorad Savićević (1877 - 1915). Skin and venereal diseases were treated by general practitioners, surgeons, internists and neurologists. Although Dr. Laza Lazarević (1851 - 1890) was not a dermatologist, but a physician and a writer, he published three papers on dermatovenereology, whereas Dr. Milorad Godjevac (1860 - 1933) wrote an important study on endemic syphilis. From 1885 to 1912, organization of dermatovenereology service has significantly improved. Considering the fact that archive documents are often missing, only approximate structure of diseases is specified: in certain monthly reports in Zaječar, out of all the diseased persons, 45% had skin or venereal diseases, while in Užice the number was 10.5%, which points to different distribution of these diseases. High percentage of dermatovenereology diseases was caused by high frequency of venereal diseases and syphilis. During the war: 1912 - 1918, the military medical service dominated, and in 1917 Prince Alexander Serbian Reserve Hospital was founded in Thessaloniki with a Department for Skin and Venereal Diseases. During this period, work of the Civilian Health Care Service was interrupted, consequently leading to a considerable aggravation of public health.
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Petzoldt, D., U. Jappe, M. Hartmann, and O. Hamouda. "Sexually transmitted diseases in Germany." International Journal of STD & AIDS 13, no. 4 (April 1, 2002): 246–53. http://dx.doi.org/10.1258/0956462021925045.

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In the former West Germany, in specific venereal diseases legislation passed in 1953, only syphilis, gonorrhoea, ulcus molle, and lymphogranuloma venereum were defined as venereal diseases and subject to mandatory notification. The proportion of unreported cases was as high as 75% for syphilis and up to 90% for gonorrhoea. Epidemiological data for the past 10 years exist only on selected populations from research studies and are summarized in this article. In the former East Germany reporting of sexually transmitted infections (STIs) was mandatory and, due to the centralized organization, underreporting was considered to be low, although no specific studies have examined this. After the unification in 1990 of the two German states the West German laws were adopted in East Germany. Since 1982 - when the first AIDS case was reported in Germany - information on AIDS cases has voluntarily been collected at the national register at the AIDS Centre of the Robert Koch Institute in Berlin. The law governing the reporting of infectious diseases has recently been revised. Under the new Protection against Infection Act, which became effective on 1 January 2001, clinical diagnoses of STIs (with the exception of hepatitis B) are no longer notifiable diseases. Laboratory reporting of positive test results for Treponema pallidum has been introduced. With T. pallidum and HIV notifications, additional disaggregated data are collected. Since T. pallidum and HIV remain the only notifiable STIs, all other STIs have to be monitored through sentinel surveillance systems. These surveillance systems are currently being established. Under the new legislation, local health authorities have to provide adequate counselling and testing services for STIs, which may be provided free of charge if necessary.
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Lalević-Vasić, Bosiljka M., and Marina Jovanović. "History of dermatology and venereology in Serbia – part IV/3: Dermatovenereology in Serbia from 1919 – 1945, part 3 / Istorija dermatologije i venerologije u Srbiji - IV/1-3: Dermatovenerologija u Srbiji u periodu 1919 - 1945." Serbian Journal of Dermatology and Venerology 2, no. 3 (August 1, 2010): 111–16. http://dx.doi.org/10.2478/v10249-011-0028-6.

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Abstract The seven years’ war (1912 - 1918) and epidemics of infectious diseases, led to a great loss of lives and medical corps of Serbia. As already stated, venereal and skin diseases were spreading in the postwar period that can be seen from medical reports of dermatovenereology institutions. They contain appropriate pathologies and some specific conditions under which they developed. In dermatovenereal pathology, venereal diseases were still dominating. In the outpatientClinic for Skin and Venereal Diseases, 10.000 patients were examined during the period from 1919 to 1921, venereal diseases accounted for 73.13%, whereas skin diseases accounted for 26.87% of all established diagnoses. A similar distribution existed at the territory of Serbia (Belgrade excluded) in 1931: venereal diseases accounted for 73.4%, and skin diseases for 26.6%; moreover, in Belgrade, the situation was even more drastic: venereal diseases accounted for 84.7%, and skin diseases for 15.3%. However, in the student population, the distribution was reversed: 43% and 57%, respectively. In regard to venereal diseases, in the series from 1919 to 1921, non-endemic syphilis was the most common disease, if serologically positive cases (latent syphilis) were added up to the clinically manifested cases. In the same series of patients, syphilis was staged as follows: syphilis I in 10%, syphilis II in 29.3%, syphilis III in 1.7%, tabes dorsalis in 0.8%, and latent syphilis in 56% of patients. In regions with endemic syphilis, from 1921 to 1925, the distribution was as follows: syphilis I in 4%, syphilis II in 49.8%, syphilis III in 18.3%, hereditary syphilis in 1.3%, and latent syphilis in 26.5% of patients. In patients suffering from gonorrhea, balanitis was found in 4.5%, and arthritis in 0.43% of cases. Generally, spreading of prostitution had a significant role, and its abolition was an important preventive action. In regard to skin diseases, in the above-mentioned series of patients, treated at the Outpatient Clinic for Skin andVenereal Diseases (1919 - 1921), scabies was the commonest skin disease (26.7%), eczemas were the second most common (21.8%), followed by pyococcal diseases (20.4%), while fungal diseases (4.5%) and skin tuberculosis (1.9%) were considerably less frequent. This is the final report about the foundation of modern dermatovenereology in Serbia.
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Dissertations / Theses on the topic "Venereal diseases"

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Ussher, Greg. "'The medical gaze and the watchful eye' : the treatment, prevention and epidemiology of venereal diseases in New South Wales c.1901 - 1925." University of Sydney, 2007. http://hdl.handle.net/2123/3565.

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Doctor of Philosophy(PhD)
From Federation in 1901 through the first three decades of the twentieth century there was a perceptible shift in modes of rule in New South Wales (NSW) related to the management of venereal diseases. At the beginning of the twentieth century a medicopenal approach was central. By 1925, persuasion and ‘responsibilisation’ were becoming important modes, and young people rather than ‘case-hardened prostitutes' were assessed as being a ‘venereal’ risk. Framing this period were three important legislative developments which informed, and were informed by, these shifts: the NSW Prisoners Detention Act 1909, the NSW Select Committee into the Prevalence of Venereal Diseases 1915 and the NSW Venereal Diseases Act 1918. At its core this thesis is concerned with examining shifting modes of rule. This thesis closely examines each. I suggest that these modes of rule can be viewed through the lens of biopolitics, and following Foucault, deploy the ‘medical gaze’ and the ‘watchful eye’ as constructs to examine the relationship between the government of self, government of others and government of the state. I use the medical gaze to describe not only the individual venereal patient attending a hospital and the body of the patient diagnosed with syphilis and/or gonorrhoea, but most importantly to describe the power relationship between the medical practitioner, the teaching hospital and the patient. I use the watchful eye in a more overarching way to suggest the suite of techniques and apparatus deployed by government to monitor and regulate the venereal body politic, both the populations perceived to be posing a venereal risk, and populations at risk of venereal infection. In relation to the venereal body and the venereal body politic, I analyse three fundamental aspects of the management of venereal diseases: treatment, prevention and epidemiology. Treatment: Over this period, treatment moved from lock institutions to outpatient clinics. Embodied in this change was a widespread institutional ambivalence towards treating venereal patients. I contend that treatment of venereal diseases was painful, prolonged and punitive precisely because of the moral sickness perceived to be at the iv heart of venereal infection. I track this ambivalence to a systemic fear of institutional ‘venerealisation’, which decreased perceptibly across the period. Closely analysing surviving patient records, I argue that in their conduct, venereal patients were often compliant, conscientious and responsible. Prevention: I argue that preventative approaches to venereal diseases became increasingly complex, and operated in three domains – preventative medicine (diagnosis, treatment and vaccination); public health prevention (notification, isolation and disinfection); and prevention education (social purity campaigns and sex hygiene). An emerging plethora of community-based organisations and campaigns began to shift the sites and practices of power. Epidemiology: I suggest that there was a shift from danger to risk in the conceptualisation of venereal diseases. This shift necessitated a focus on factors affecting populations, as opposed to factors affecting individuals. This in turn led to the deployment of various techniques to monitor the conduct of venereal populations. The NSW Venereal Diseases Act 1918 created two important new venereal categories: the ‘notified person’ and the ‘defaulter,’ both of which came to permeate renditions of venereal patients throughout the 20th century.
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Lemar, Susan. "Control, compulsion and controversy: venereal diseases in Adelaide and Edinburgh 1910-1947." Title page, contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phl548.pdf.

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Includes bibliographical references (leaves 280-305). Argues that despite the liberal use of social control theory in the literature on the social history of venereal diseases, rationale discourses do not necessarily lead to government intervention. Comparative analysis reveals that culturally similar locations can experience similar impulses and constraints to the development of social policy under differing constitutional arrangements.
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Ussher, Gregory Ronald. "The 'medical gaze' and the 'watchful eye' the treatment, prevention and epidemiology of venereal diseases in New South Wales c.1901-1925 /." Connect to full text, 2006. http://hdl.handle.net/2123/3565.

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Thesis (Ph. D.)--University of Sydney, 2007.
Title from title screen (viewed October 9, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Philosophical and Historical Inquiry, Faculty of Arts. Degree awarded 2007; theses submitted 2006. Includes bibliographical references. Also available in print form.
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Bridges, Jennifer. "Reclaiming Female Virtue: Social Hygiene, Venereal Disease and Texas Reclamation Centers during World War I." Thesis, University of North Texas, 2018. https://digital.library.unt.edu/ark:/67531/metadc1404551/.

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During the Progressive Era in the United States, social hygiene reformers underwent a fundamental change in their stance toward women accused of prostitution or promiscuous behavior. Rather than viewing such women as unfortunate victims of circumstance who were worthy of compassion, many Progressives deemed them as predatory villains who instead deserved incarceration, forced rehabilitation, and non-consenting medical interference. Texas, due to the many military bases within its borders, became a key battleground in this moral crusade against women as the carriers and proliferators of VD. "Promiscuous" women were seen as not only dangerous to the soldiers but also as a threat to the nation's security, creating an environment that led Texas Progressives to suppress women's civil liberties in the name of protecting soldiers. The catalyst for this change in attitude was World War I. The Great War brought to the forefront an unpleasant reality facing a significant percentage of America's fighting men: venereal disease. While combating sexually transmitted diseases was a serious medical and manpower concern for the military in the era before penicillin, the sole focus on women as the carriers and proliferators of VD led to a nationwide campaign against the "social evil" that demonized women and led to the suspension of thousands of women's habeas corpus rights. This dissertation examines how the twin crusades of Progressivism and the War to End All Wars created conditions in Texas that for many women meant appalling repression rather than progress toward the enjoyment of greater equality.
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Rockafellar, Nancy. "Making the world safe for the soldiers of democracy : patriotism, public health and venereal disease control on the West Coast, 1910-1919 /." Thesis, Connect to this title online; UW restricted, 1990. http://hdl.handle.net/1773/10354.

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Wäster, Larsson Petra. "UVA/B induced redox alterations and apoptosis in human melanocytes." Doctoral thesis, Linköpings universitet, Dermatologi och venerologi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8880.

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Malignant melanoma is one of the most rapidly increasing cancers and accounts for about three-quarter of all skin cancer deaths worldwide. Despite compelling evidence that ultraviolet (UV) irradiation causes melanoma the knowledge how various wavelength spectra affect the balance between proliferation and apoptosis controlling the homeostasis of the melanocyte population is still limited. The aim of this thesis was to elucidate the regulation of UVA/B induced apoptotic signaling in human epidermal melanocytes in vitro in relation to redox alterations and antioxidant photoprotection. UVA irradiation induced changes in plasma membrane stability, decreased cell proliferation and increased apoptosis. In comparison, melanocyte plasma membrane was markedly resistant to UVB irradiation although apoptosis was triggered. Thus, UVA irradiation should not be overlooked as an etiologic factor in melanoma development. Further, after irradiation with UVA/B we found alterations in redox state manifested by a reduction of intracellular GSH levels, translocation of nuclear factor-κB from the cytosol to the nucleus, an increase of γ-glutamylcysteine synthetase, the rate-limiting enzyme in GSH synthesis, and an increased apoptosis frequency. α-Tocopherol provided photoprotection through several modes of action affecting redox alterations and signaling, stabilizing the plasma membrane, and decreased proliferation and apoptosis rate, while β-carotene did not show the same protective capacity. Altogether, α-tocopherol might be a useful substance in protecting melanocytes from UV induced damage. We demonstrate UVA/B irradiation to activate the intrinsic pathway of apoptosis in melanocytes where translocation of Bcl-2 family proteins to the mitochondria modulates the apoptosis signal. Interestingly, the anti-apoptotic Bcl-2 family proteins generally thought to be attached to membranes, were localized in the cytosol before UV irradiation and translocated to the mitochondria in the surviving population, which might be a critical event in preventing apoptotic cell death. Lysosomal cathepsins were released to the cytosol acting as pro-apoptotic mediators upstream of activation and translocation of Bax to the mitochondria. When melanocytes were exposed to UVA, p53 participated in apoptosis regulation through interaction with Bcl-2 family proteins, while UVB induced p53-transcriptional activity and apoptosis involving lysosomal membrane permeabilization. Thus, depending on the UV wavelength p53 mediated apoptosis in melanocytes by transcriptional dependent or independent activity. These results emphasize p53 as an important pro-apoptotic component in the regulation of apoptosis. This thesis gives new insight in the harmful and various effects of different wavelengths within the UV spectrum on human melanocytes in vitro. Improved knowledge of the apoptosis regulatory systems in melanocytes might lead to a better understanding of the formation of pigment nevi and malignant melanoma and, in the future, provide better strategies to prevent and eliminate tumor development and progression.
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Kennard, Benjamin, Allison Cobble, Amy Gravitte, Kaleigh Galloway, Jen Kintner, Jennifer Hall, and Stacy C. Brown. "Quantification of Progesterone and 17-β Estradiol in Mouse Serum by Liquid Chromatography-Tandem Mass Spectrometry." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/asrf/2020/presentations/45.

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Quantification of progesterone and 17-β estradiol in mouse serum by liquid chromatography-tandem mass spectrometry Authors: Benjamin Kennard, Allison Cobble, Amy Gravitte, Keleigh Galloway, Jen Kintner, Jennifer Hall, Stacy Brown Introduction: In the United States, Chlamydia trachomatis is a commonly appearing sexually transmitted infection1. It affects the U.S. healthcare system to a tune of about $500 million dollars annually2. In women, it generally appears asymptomatic and can lead to severe secondary complications such as pelvic inflammatory diseases or infertility1. Female sex hormones, estrogen and progesterone, are being identified to have a role in chlamydial infection. Specifically, this study aims to create quantification methods to detect levels of estrogen and progesterone in mice, infected with Chlamydia muridarum, plasma samples. Methods: Progesterone samples were prepared using solid-liquid extraction (SLE+) cartridges with ethyl acetate as the elution solvent. Estradiol samples were prepared using liquid-liquid extraction (LLE) with methyl tert-butyl ether and subsequent derivatization with DMIS. Following sample preparation, hormones were quantified in samples using LC-MS/MS with a gradient elution of 1 mM ammonium fluoride in water and acetonitrile. The separation was achieved using a UCT C18 column (100 x 21.mm, 1.8 μm particle size) maintained at 50oC. The mass spectrometer was set up to isolate molecular ions for progesterone (m/z 315.0910) and derivatized estradiol (m/z 431.1835). Quantification was facilitated by the use of deuterium-labeled internal standards and their corresponding molecular ions in the mass spectrometer (d9-progesterone; m/z 324.1230 and d5-estradiol; m/z 436.2922). Results: Several aspects of the assay presented have been optimized for maximum analyte recovery and analytical sensitivity, including column choice, mobile phase, derivatizing agents for estradiol, and extraction protocols for progesterone. The LC-MS/MS method was investigated for precision and accuracy over three separate days. The dynamic range of the progesterone assay was 5 – 100 ng/mL, with a limit of detection of 1 ng/mL. Likewise, the estradiol assay was linear in the range of 5 – 100 ng/mL, with a limit of detection of 0.5 ng/mL. The average precision, represented by % RSD was 0.74 – 8.5% and 6.3 – 13.4% for progesterone and estradiol, respectively. The accuracy of the method, represented by % error was 1.6 – 14.4% and 4.0 – 10.5% for progesterone and estradiol, respectively. Successful validation was defined as < 15% RSD and error (< 20% at the limit of quantification), per current FDA Guidelines. Conclusions: The developed LC-MS/MS method is specific for progesterone and estradiol, and the extraction is suitable for preparation of mouse serum samples. This assay could be successfully applied to hormone quantification in mouse samples to support the investigation of the link between chlamydia infection and hormone levels in female animals. References 1. Chlamydia - 2017 Sexually Transmitted Diseases Surveillance. https://www.cdc.gov/std/stats17/chlamydia.htm. Accessed October 23, 2018. 2. Owusu-Edusei K, Chesson HW, Gift TL, et al. The Estimated Direct Medical Cost of Selected Sexually Transmitted Infections in the United States, 2008. Sex Transm Dis. 2013;40(3):197-201. doi:10.1097/OLQ.0b013e318285c6d2
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Nie, Yali. "Automatic Melanoma Diagnosis in Dermoscopic Imaging Base on Deep Learning System." Licentiate thesis, Mittuniversitetet, Institutionen för elektronikkonstruktion, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-41751.

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Melanoma is one of the deadliest forms of cancer. Unfortunately, its incidence rates have been increasing all over the world. One of the techniques used by dermatologists to diagnose melanomas is an imaging modality called dermoscopy. The skin lesion is inspected using a magnification device and a light source. This technique makes it possible for the dermatologist to observe subcutaneous structures that would be invisible otherwise. However, the use of dermoscopy is not straightforward, requiring years of practice. Moreover, the diagnosis is many times subjective and challenging to reproduce. Therefore, it is necessary to develop automatic methods that will help dermatologists provide more reliable diagnoses.  Since this cancer is visible on the skin, it is potentially detectable at a very early stage when it is curable. Recent developments have converged to make fully automatic early melanoma detection a real possibility. First, the advent of dermoscopy has enabled a dramatic boost in the clinical diagnostic ability to the point that it can detect melanoma in the clinic at the earliest stages. This technology’s global adoption has allowed the accumulation of extensive collections of dermoscopy images. The development of advanced technologies in image processing and machine learning has given us the ability to distinguish malignant melanoma from the many benign mimics that require no biopsy. These new technologies should allow earlier detection of melanoma and reduce a large number of unnecessary and costly biopsy procedures. Although some of the new systems reported for these technologies have shown promise in preliminary trials, a widespread implementation must await further technical progress in accuracy and reproducibility.  This thesis provides an overview of our deep learning (DL) based methods used in the diagnosis of melanoma in dermoscopy images. First, we introduce the background. Then, this paper gives a brief overview of the state-of-art article on melanoma interpret. After that, a review is provided on the deep learning models for melanoma image analysis and the main popular techniques to improve the diagnose performance. We also made a summary of our research results. Finally, we discuss the challenges and opportunities for automating melanocytic skin lesions’ diagnostic procedures. We end with an overview of a conclusion and directions for the following research plan.
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Palfreyman, Harriet. "Visualising venereal disease in London c.1780-1860." Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/55107/.

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This thesis explores the various roles that visual representations played in the theoretical understanding of, and practical approaches to, venereal disease in London’s medical marketplace from around 1780 to 1860. Venereal disease was understood in a variety of ways, and conceptualised within a number of different medical disciplines, such as pathology and dermatology. The analytic lens of visual representation allows the historian to explore the complexities of these understandings. This thesis therefore contributes to the literature on the historicising of disease. The period under discussion was one of enormous change in medical theory, practice and disciplinary organisation. Disease was being conceptualised as something physical within the body, meaning images of the disease took on new meanings. Furthermore, these representations played an important role in medical education of the period, as well as in the legitimisation of new disciplines. Within these new theoretical paradigms and institutional spaces, various new meanings were created for the visual representations, and their creators and users had to employ various strategies to limit their meaning and control their interpretations. This thesis utilises a variety of visual and material representations – atlas illustrations, wax moulages, paintings, casts, models and pathological preparations – to see how meaning was negotiated for these visual representations. Venereal disease is a particularly complex case, as it was considered difficult to depict, therefore debates and disagreements over how it was to be visualised reveal much about how the disease was conceptualised. Through five chapters, the thesis explores how these representations functioned within different spaces in London’s medical marketplace, such as public museums, private schools, hospitals and university medical departments.
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Bivik, Cecilia. "Regulation of UV induced apoptosis in human melanocytes." Doctoral thesis, Linköping : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8749.

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Books on the topic "Venereal diseases"

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Llewellyn-Jones, Derek. Herpes, AIDS and other sexually transmitted diseases. London: Faber, 1985.

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Adler, Michael W. ABC of sexually transmitted diseases. 5th ed. London: BMJ, 2003.

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M, Felman Yehudi, ed. Sexually transmitted diseases. New York: Churchill Livingstone, 1986.

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Astruc, Jean. A treatise of the venereal disease. New York: Garland Pub., 1985.

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W, Adler Michael, ed. ABC of sexually transmitted infections. 5th ed. London: BMJ, 2004.

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Organization, World Health, ed. WHO expert committee on venereal diseases and treponematoses: Sixth report. Geneva: World Health Organization, 1986.

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Hanley, Anne R. Medicine, Knowledge and Venereal Diseases in England, 1886-1916. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-32455-5.

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David, Taylor-Robinson, ed. Clinical problems in sexually transmitted diseases. Dordrecht: Nijhoff, 1985.

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Buchan, William. Observations concerning the prevention and cure of the venereal disease. New York: Garland Pub., 1985.

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P, Lowry Thomas. Venereal disease and the Lewis and Clark expedition. Lincoln: University of Nebraska Press, 2004.

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Book chapters on the topic "Venereal diseases"

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Turner, J. Rick, J. Rick Turner, Jonathan Newman, Alexandra Erdmann, Erin Costanzo, Leah Rosenberg, Jonathan Newman, et al. "Venereal Diseases." In Encyclopedia of Behavioral Medicine, 2031. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101836.

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Jain, Dinesh Kumar. "Venereal diseases." In Homeopathy, 165–72. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003228622-42.

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Henry, Olsen. "Venereal Diseases." In Sexual Adjustment in Marriage, 266–68. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003389286-74.

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Lancaster, H. O. "Syphilis and Other Venereal Diseases." In Expectations of Life, 186–90. New York, NY: Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-1003-0_17.

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Breathnach, S. M., and J. Ashworth. "Scabies and Selected Non-venereal Dermatoses." In Immunology of Sexually Transmitted Diseases, 223–36. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1255-7_10.

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Chapel, T. A. "Barrier methods of contraception as prophylaxis against venereal diseases." In Uncommon Infections and Special Topics, 259–66. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4902-7_18.

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Hanley, Anne R. "Introduction." In Medicine, Knowledge and Venereal Diseases in England, 1886-1916, 1–23. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32455-5_1.

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Hanley, Anne R. "Training Competent Generalists." In Medicine, Knowledge and Venereal Diseases in England, 1886-1916, 25–62. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32455-5_2.

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Hanley, Anne R. "Postgraduate Specialism." In Medicine, Knowledge and Venereal Diseases in England, 1886-1916, 63–106. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32455-5_3.

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Hanley, Anne R. "Under the Microscope." In Medicine, Knowledge and Venereal Diseases in England, 1886-1916, 107–46. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32455-5_4.

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Conference papers on the topic "Venereal diseases"

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Sumiati, Eugenia Audrey, Agung Triayudi, and Lia Kamelia. "Application of Certainty Factor Method to Diagnose Venereal Diseases Using Confusion Matrix for Multi-Class Classification." In 2022 16th International Conference on Telecommunication Systems, Services, and Applications (TSSA). IEEE, 2022. http://dx.doi.org/10.1109/tssa56819.2022.10063893.

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Wei, Qing, Wenbin Wang, Rui Peng, and Yi Ding. "Optimal Screening Interval for a Person Vulnerable to Venereal Disease." In 2016 Second International Symposium on Stochastic Models in Reliability Engineering, Life Science and Operations Management (SMRLO). IEEE, 2016. http://dx.doi.org/10.1109/smrlo.2016.78.

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Maffei, Rafael Tuzino Leite Neves, Adriel Rêgo Barbosa, Andre Felipe Candeas Amorim, Gabriel Pinheiro Martins de Almeida e. Souza, Pedro Henrique Almeida Fraiman, João Victor Cabral Correia Férrer, Victor Cardoso de Faria, Márcio Pinheiro Lima, Ruan Gambardella Rosalina de Azevedo, and Sandro Luiz de Andrade Matas. "Neurosyphilis causing bilateral optic perineuritis." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.568.

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Introduction: Optic perineuritis is a rare disorder with multiple possible etiologies, including systemic autoimmune or infectious syndromes and, more rarely, neurosyphilis. The aim of this report is to describe an uncommon manifestation of this reemerging infectious disease. Case report based on a retrospective analysis of the medical records of the patient. Case report: A previously healthy 35-year-old female presented to the hospital with a seven-day history of progressive right eye vision loss and pain on extraocular movement, with development of a pink maculopapular rash on the trunk. On the sixth day of her disease, similar symptoms appeared in the contralateral eye. Physical examination showed reduced fotomotor reflex and finger counting at 50 cm in both eyes. Magnetic resonance imaging revealed bilateral and circumferential thickening with enhancement of the optic nerve sheath, suggesting bilateral optic nerve perineuritis. Serum Venereal Disease Research Laboratory (VDRL) was 1/64 and cerebrospinal fluid (CSF) showed 440 cells (86% lymphocytes), proteins 97 mg/dL, glucose 47 mg/dL, lactate 21 mg/dL and VDRL 1/4. She was treated with IV crystalline penicillin for 21 days and had partial improvement of bilateral vision within two months. At follow-up, her visual acuity was 20/40 in the right eye and 20/100 in the left; her CSF normalized, with nonreactive VDRL. Conclusion: Neurosyphilis is a treatable cause of optic perineuritis, and its recognition is important to establish the right antibiotic treatment.
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Gonçalves, Victoria Veiga Ribeiro, Isabela Fonseca Risso, Pedro Vinícius Brito Alves, Guilherme Diogo Silva, Jorge Fernando de Miranda Pereira, Coralia Gabrielle Vieira Silveira, Paula Baleeiro Rodrigues Silva, et al. "Neurosyphilis causing stroke in young adult: a case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.127.

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Introduction: Up to 10% of strokes affect people under 45 years old. Syphilis is most common in adults. Fourteen percent of neurosyphilis cases have stroke its first manifestation. Objectives: To discuss neurosyphilis as an overlooked etiology for stroke. Design and setting: The case occurred in a public secondary care hospital located in São Paulo - Brazil. Methods: We present a case report of a 28-year-old woman brought to the emergency department due to acute ataxia. Previous history shows stroke at the age of 20 years old. Brain MRI showed ischemia in both cerebellar hemispheres, pons and midbrain. Arterial angiography showed segmental basilar artery stenosis. Serum laboratory tests showed Venereal Disease Research Laboratory (VDRL) of 1:128. Cerebrospinal fluid (CSF) analysis showed 117 cells (predominantly lymphomononuclear), protein 81 mg/ dl, normal glucose and VDRL of 1:8, confirming neurosyphilis. Treatment with intravenous penicillin led to partial improvement in ataxia before discharge. Discusion: A high percentage (up to 80%) of diagnostical errors is expected when stroke is caused by neurosyphilis. Misdiagnosis may compromise secondary prevention. It is possible that the first stroke was also caused by neurosyphilis in our patient. The involvement of the vertebrobasilar territory occurs in 25% of patients with meningovascular neurosyphilis. Basilar stenosis is typical for neurosyphilis. Conclusion: Stroke in young adults should include VDRL to screen for neurosyphilis. If positive, it should indicate a CSF exam.
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Araujo, Maria Alix Leite, Ana Beatriz Barbosa Esteves, Ana Fatima Braga Rocha, Geraldo Bezerra da Silva Junior, and Angelica Espinosa Miranda. "Fatores associados à prematuridade em casos notificados de sífilis congênita durante o período de escassez de penicilina." In XIV Congresso da Sociedade Brasileira de DST - X Congresso Brasileiro de AIDS - V Congresso Latino Americano IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/dst-2177-8264-202335s1052.

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Introdução: A sífilis é uma infecção sistêmica que, quando acomete a gestante, pode ser transmitida ao bebê, causando a sífilis congênita, com consequências graves, entre elas, a prematuridade. Objetivo: Analisar os fatores associados à prematuridade em casos notificados de sífilis congênita no município de Fortaleza, Ceará, Brasil. Métodos: Estudo transversal realizado em dez maternidades públicas de Fortaleza, Ceará. Foram incluídos 478 casos notificados de sífilis congênita no ano de 2015, e os dados foram coletados das fichas de notificação, dos prontuários das mães e dos bebês, e do cartão de pré-natal. Para a análise bivariada foram utilizados os teste do χ2 de Pearson e o teste Exato de Fisher, considerando p<0,05. Realizou-se regressão logística múltipla apresentando a razão de chances (OR) com intervalo de confiança de 95% (IC95%). Resultados: Encontrou-se 15,3% de prematuridade em gestantes com sífilis. A titulação do Venereal Disease Research Laboratory (VDRL) >1:8 no parto (OR 2,46, IC95% 1,33–4,53, p=0,004), o não tratamento da gestante ou tratamento realizado com drogas diferentes da penicilina durante o pré-natal (OR 3,52, IC95% 1,74–7,13, p<0,001) estiveram associados a maiores chances de prematuridade. Conclusão: A prematuridade decorrente da sífilis congênita é um agravo evitável desde que as gestantes com sífilis sejam manejadas adequadamente. As fragilidades na assistência pré-natal estão associadas a esse desfecho, ressaltando a importância da efetiva implementação das políticas públicas voltadas para a qualidade do pré-natal.
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Miranda, Ana Clara Izidoro Barreto, Frederico Martins Oliveira, Larissa Maria Borges, Laura de Oliveira Roveri, Tomas Varella Costa Russo, and Wanessa Marcela dos Santos Oliveira. "Apresentação atípica de sífilis secundária em uma pessoa que vive com HIV/AIDS: relato de caso." In XIV Congresso da Sociedade Brasileira de DST - X Congresso Brasileiro de AIDS - V Congresso Latino Americano IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/dst-2177-8264-202335s1078.

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Introdução: Paciente mulher trans, reclusa, vivendo com o Vírus da Imunodeficiência Humana (HIV) em abandono de tratamento há cerca de um ano com carga viral 10121 e CD4+ 663. Apresentou lesões em placas, infiltradas, eritemato- arroxeada, descamativas, múltiplas em toda extensão do corpo poupando região genital, anal, palmar e plantar, não dolorosas e não pruriginosas, há 4 meses. Paciente negou sintomas sistêmicos, inclusive neurológicos e diagnóstico prévio de outras infecções sexualmente transmissíveis (ISTs). Foi realizado propedêutica para diagnósticos diferenciais, tendo sido compatível com sífilis secundária. Objetivo: Descrever uma apresentação atípica de sífilis secundária em uma pessoa que vive com HIV/AIDS (PVHA) e a sistematização da investigação de diagnósticos diferenciais. Métodos: Trata-se de um relato de caso de uma única paciente, assistida por um ambulatório especializado no interior de São Paulo no ano de 2023. Resultados: após biópsia de lesão, foi evidenciado infiltrado plasmocitário, sugestivo de sífilis, e imuno-histoquímica negativa para malignidade. Obteve-se Venereal Disease Research Laboratory (VDRL) com título de 1/512 e CIE para fungos negativas. Foi iniciado o tratamento com penicilina benzatina 2.400.000 UI por 3 semanas consecutivas. Houve regressão significativa das lesões e queda do título de VDRL já após o primeiro mês de tratamento. Conclusão: No contexto de imunossupressão pelo HIV, as lesões de pele podem ter etiologias variáveis, bem como se apresentarem de maneira atípica. Dessa maneira, uma investigação diferencial e minuciosa permite o diagnóstico conclusivo e a instituição de seu efetivo tratamento.
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Beretta, Luiza de Lima, Arthur Costa Nascimento, and Diogo Fernandes dos Santos. "Community-acquired pneumococcal meningoencephalitis associated with neurosyphilis in an immunocompetent patient: case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.482.

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Case report: A 28-year-old man with no comorbidities was admitted to our institution with a history of sudden holocranial headache, associated with fever, lowered level of consciousness and meningismus with the need for orotracheal intubation. Computed tomography of the brain was normal and the cerebrospinal fluid (CSF) on 05/28/2022 was yellowish, cloudy, glucose 6.0 mg/ dL, protein 752 mg/dL, cells 25,600 mm³ (neutrophils 92%, lymphocytes 5%), red blood cells 258 mm³, CSF Venereal Disease Research Laboratory (VDRL) 1/8, serum VDRL 1/32, treponemal test positive, human immunodeficiency virus (HIV) negative. Ceftriaxone, ampicillin, and acyclovir were empirically started. Pneumococcus was identified in the culture of CSF and blood cultures on admission and the antibiotic regimen was adequate, maintaining only ceftriaxone. Antibiotic therapy lasted 14 days, he was discharged after 16 days of hospitalization, for outpatient follow-up, with no neurological deficits. Control lumbar puncture on 12/23 revealed clear, colorless CSF, glucose 56 mg/dL, total protein 31.8 mg/dL, no cells or red blood cells, cultures negative. Discussion: Streptococcus pneumoniae is the most common cause of meningitis in adults, in older adults and in the current era, neurosyphilis, is most frequently seen in persons with HIV. There are no similar cases described in the literature. Despite the effectiveness of current antibiotics in clearing bacteria from the CSF, bacterial meningitis continues to cause significant morbidity and mortality worldwide. We describe a rare case of an immunocompetent patient with communityacquired pneumococcal meningoencephalitis associated with neurosyphilis treated with ceftriaxone who did not present sequelae or need for retreatment. Conclusion: It´s a rare cause of meningoencephalitis and has significant morbidity and mortality. More studies are needed regarding susceptibility to meningoencephalitis by multiple germs in immunocompetent patients.Case report: A 28-year-old man with no comorbidities was admitted to our institution with a history of sudden holocranial headache, associated with fever, lowered level of consciousness and meningismus with the need for orotracheal intubation. Computed tomography of the brain was normal and the cerebrospinal fluid (CSF) on 05/28/2022 was yellowish, cloudy, glucose 6.0 mg/ dL, protein 752 mg/dL, cells 25,600 mm³ (neutrophils 92%, lymphocytes 5%), red blood cells 258 mm³, CSF Venereal Disease Research Laboratory (VDRL) 1/8, serum VDRL 1/32, treponemal test positive, human immunodeficiency virus (HIV) negative. Ceftriaxone, ampicillin, and acyclovir were empirically started. Pneumococcus was identified in the culture of CSF and blood cultures on admission and the antibiotic regimen was adequate, maintaining only ceftriaxone. Antibiotic therapy lasted 14 days, he was discharged after 16 days of hospitalization, for outpatient follow-up, with no neurological deficits. Control lumbar puncture on 12/23 revealed clear, colorless CSF, glucose 56 mg/dL, total protein 31.8 mg/dL, no cells or red blood cells, cultures negative. Discussion: Streptococcus pneumoniae is the most common cause of meningitis in adults, in older adults and in the current era, neurosyphilis, is most frequently seen in persons with HIV. There are no similar cases described in the literature. Despite the effectiveness of current antibiotics in clearing bacteria from the CSF, bacterial meningitis continues to cause significant morbidity and mortality worldwide. We describe a rare case of an immunocompetent patient with communityacquired pneumococcal meningoencephalitis associated with neurosyphilis treated with ceftriaxone who did not present sequelae or need for retreatment. Conclusion: It´s a rare cause of meningoencephalitis and has significant morbidity and mortality. More studies are needed regarding susceptibility to meningoencephalitis by multiple germs in immunocompetent patients.
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Santo, Ana Flávia Vieira do Espírito. "ASPECTOS EPIDEMIOLÓGICOS E CONCEITUAIS DA SÍFILIS CONGÊNITA EM UMA MATERNIDADE DO PLANALTO NORTE CATARINENSE." In I Congresso Brasileiro de Estudos Epidemiológicos On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/epidemion/7122.

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Introdução: A sífilis trata-se de um dos mais importantes e prevalentes agravos de saúde pública, sendo uma das principais infecções sexualmente transmissíveis (IST). Transmitida através da bactéria Treponema pallidum, se dá, prevalentemente, através do contágio sexual e da transmissão vertical. O diagnóstico precoce e tratamento eficaz da sífilis durante o intercurso da gestação se fazem crucial para reduzir a transmissibilidade fetal e seus desfechos. Objetivo: Identificar a incidência da sífilis gestacional e congênita, e descrever o perfil socioepidemiológico do binômio mãe-feto infectados. Materiais e Métodos: Trata-se de um estudo de caráter quali-quantitativo, retrospectivo, descritivo e exploratório, a partir da análise documental de 38 prontuários eletrônicos de gestantes diagnosticada com sífilis, durante o ano de 2018 a 2020, em uma maternidade do planalto norte catarinense. Resultados: Dentre as características socioepidemiológicas da sífilis gestacional, prevaleceram mulheres brancas, jovens, de baixa escolaridade, que realizaram o pré-natal e o tratamento, de forma correta ou incorreta. Em relação à sífilis congênita, 100% do perfil dos recém-nascidos se enquadravam como sendo masculinos, brancos, nascidos a termo, com peso adequado para a idade gestacional, e APGAR satisfatório, todos foram diagnosticados através da sorologia VDRL (Venereal Disease Research Laboratory), sendo em sua maioria assintomáticos e tratados com penicilina cristalina. Conclusão: A sífilis congênita trata-se de afecção grave, que apesar de ser passível de prevenção, diagnóstico precoce e tratamento, continua tendo altos índices de incidência e prevalência, podendo refletir em uma falha da atenção materno-infantil brasileira ofertada, principalmente no que tange a atenção primária, requerendo estratégias maiores de promoção e prevenção à saúde.
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Yonegura, Winny Hirome Takahashi, Ives Hideki Okata de Oliveira, Gabriela Camargo Cardoso, Roberto Ferreira Oizumi, and Josana Aparecida Dranka Horvath. "Neurossífilis: análise epidemiológica dos casos diagnosticados em um centro de referência do oeste do Paraná." In XIV Congresso da Sociedade Brasileira de DST - X Congresso Brasileiro de AIDS - V Congresso Latino Americano IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/dst-2177-8264-202335s1236.

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Introdução: A sífilis despontou nos últimos anos como um grave problema de saúde pública. Entre suas complicações destaca-se a neurossífilis, evento de difícil diagnóstico e manejo clínico. São escassos os estudos desse tema, representando um grande desafio para a prática clínica. Objetivo: Avaliar pacientes diagnosticados com neurossífilis e seus aspectos epidemiológicos, procurando relacionar a evolução da sífilis para a forma neurológica com idade, sexo, raça, estado civil, escolaridade, sintomas, comorbidades, resultados de exames como Venereal Disease Research Laboratory (VDRL) e análise de líquor. Métodos: Foram analisados dados com base em prontuários médicos obtidos no Centro Especializado em Doenças Infecto Parasitárias (CEDIP), localizado em Cascavel, Paraná, no período de 2018 a 2020. Resultados: Foram documentados quatro casos de neurossífilils no período analisado. Apesar de um número reduzido de pacientes, foi possível analisar o quanto os pacientes são heterogêneos em vários aspectos, principalmente em relação às manifestações clínicas (desde paciente assintomático, sintomas inespecíficos como cefaleia até um quadro mais clássico tipo uveíte) e aos valores de VDRL séricos. Contudo, destaca-se que os quatro pacientes deste estudo apresentavam como comorbidade diabetes mellitus, o que sabidamente é um fator importante de imunossupressão. Conclusão: A pesquisa realçou a complexidade que é o diagnóstico da neurossífilis, visto que a doença pode apresentar sintomas inespecíficos ou até mesmo ser assintomática, acarretando vários casos subdiagnosticados. Dessa forma, fica evidente a importância que tem a avaliação clínica detalhada, o seguimento dos pacientes após tratamento, os critérios para punção lombar e a análise liquórica, a fim de fazer o diagnóstico e, então, o tratamento dessa doença.
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Kierski, Juliana da Costa Duarte, Claudia Alexandra de Andrade, and Karolyne Gaio Ribeiro de Aragão. "Dessensibilização à penicilina para o tratamento da sífilis em gestantes: um relato de experiência exitosa." In XIV Congresso da Sociedade Brasileira de DST - X Congresso Brasileiro de AIDS - V Congresso Latino Americano IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/dst-2177-8264-202335s1006.

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Introdução: A sífilis é uma infecção bacteriana causada pelo Treponema pallidum. A transmissão ocorre principalmente por contato sexual, mas também pode acontecer por transmissão vertical de uma mãe infectada para o filho durante a gestação ou parto. A dessensibilização à penicilina é recomendada para mulheres grávidas com sífilis que são alérgicas a betalactâmicos. Objetivo: Relatar o procedimento exitoso de dessensibilização à penicilina realizado em uma gestante com sífilis do município de Pinhais, Paraná, com o intuito de estimular a realização dessa prática em outros municípios, contribuindo para reduzir os casos de sífilis congênita. Métodos: Trata-se de um relato de estudo de caso que foi vivenciado em fevereiro de 2023 e registrado pela equipe multiprofissional de saúde mobilizada, que envolveu profissionais do município de Pinhais e da Secretaria Estadual de Saúde para viabilizar a disponibilização de um hospital com leito de UTI, necessário para a realização do procedimento. Resultados: Não houve nenhuma intercorrência durante o procedimento de dessensibilização à penicilina efetuado na gestante. A primeira aplicação da penicilina G benzatina 2.400.000 UI foi realizada com a paciente internada no hospital e as demais aplicações foram realizadas sem a necessidade de internamento. Os exames de acompanhamento da gestante já demonstraram queda na titulação do Venereal Disease Research Laboratory (VDRL), de 1:16 para 1:8. Conclusão: Considerando os aumentos crescentes de casos de sífilis em gestantes e a importância do tratamento adequado, o processo de dessensibilização realizado permitiu a execução do seu tratamento de forma segura e efetiva, envolvendo procedimentos que não exigem grande complexidade e que podem ser utilizados como mais uma importante forma de prevenção da sífilis congênita.
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