Journal articles on the topic 'VEGFRs'
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Bais, Swarna, Elizabeth Wise, Eric M. Harris, Amy Meacham, and Christopher R. Cogle. "AML Depends on VEGFR1 and Not VEGFR2 for Proliferation and Protection From Chemotherapy,." Blood 118, no. 21 (November 18, 2011): 3598. http://dx.doi.org/10.1182/blood.v118.21.3598.3598.
Full textZarkada, Georgia, Krista Heinolainen, Taija Makinen, Yoshiaki Kubota, and Kari Alitalo. "VEGFR3 does not sustain retinal angiogenesis without VEGFR2." Proceedings of the National Academy of Sciences 112, no. 3 (January 5, 2015): 761–66. http://dx.doi.org/10.1073/pnas.1423278112.
Full textWitmer, Antonella N., Jiapei Dai, Herbert A. Weich, Gijs F. J. M. Vrensen, and Reinier O. Schlingemann. "Expression of Vascular Endothelial Growth Factor Receptors 1, 2, and 3 in Quiescent Endothelia." Journal of Histochemistry & Cytochemistry 50, no. 6 (June 2002): 767–77. http://dx.doi.org/10.1177/002215540205000603.
Full textMorimoto, Yukina, Masahiro Toda, Ryota Tamura, Kentarou Ohara, Yumiko Oishi, and Kazunari Yoshida. "IMT-02 VEGF RECEPTORS EXPRESSION AND REPORT OF CLINICAL TRIAL OF PEPTIDE VACCINE IN SKULL BASE CHORDOMA." Neuro-Oncology Advances 1, Supplement_2 (December 2019): ii17. http://dx.doi.org/10.1093/noajnl/vdz039.077.
Full textFeng, Yan, Ying Li, Xinling Yang, Limin Han, Luning Wang, Shan Gao, Ruixue Yin, et al. "Direct evidence of VEGF-mediated neuroregulation and afferent explanation of blood pressure dysregulation during angiogenic therapy." Frigid Zone Medicine 1, no. 2 (December 1, 2021): 119–26. http://dx.doi.org/10.2478/fzm-2021-0015.
Full textCoon, Brian G., Nicolas Baeyens, Jinah Han, Madhusudhan Budatha, Tyler D. Ross, Jennifer S. Fang, Sanguk Yun, Jeon-Leon Thomas, and Martin A. Schwartz. "Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex." Journal of Cell Biology 208, no. 7 (March 23, 2015): 975–86. http://dx.doi.org/10.1083/jcb.201408103.
Full textDewaele, B., G. Floris, R. Sciot, H. Prenen, A. Wozniak, L. Guillou, J. Coindre, C. Fletcher, P. Schöffski, and M. Debiec-Rychter. "Tyrosine kinases as possible therapeutic targets in pulmonary artery intimal sarcoma." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 10055. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.10055.
Full textTamura, Ryota, Yukina Morimoto, Mizuto Sato, Tetsuro Hikichi, Kazunari Yoshida, and Masahiro Toda. "A Pilot Study of the Adverse Events Caused by the Combined Use of Bevacizumab and Vascular Endothelial Growth Factor Receptor-Targeted Vaccination for Patients with a Malignant Glioma." Vaccines 8, no. 3 (September 2, 2020): 498. http://dx.doi.org/10.3390/vaccines8030498.
Full textZhang, Huanxiang, Laszlo Vutskits, Michael S. Pepper, and Jozsef Z. Kiss. "VEGF is a chemoattractant for FGF-2–stimulated neural progenitors." Journal of Cell Biology 163, no. 6 (December 22, 2003): 1375–84. http://dx.doi.org/10.1083/jcb.200308040.
Full textFuruya, Mitsuko, Kentaro Kurasawa, Kiyotaka Nagahama, Kae Kawachi, Akinori Nozawa, Tsuneo Takahashi, and Ichiro Aoki. "Disrupted Balance of Angiogenic and Antiangiogenic Signalings in Preeclampsia." Journal of Pregnancy 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/123717.
Full textMasood, Rizwan, Jie Cai, Tong Zheng, D. Lynne Smith, David R. Hinton, and Parkash S. Gill. "Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor–positive human tumors." Blood 98, no. 6 (September 15, 2001): 1904–13. http://dx.doi.org/10.1182/blood.v98.6.1904.
Full textInder, Marie K., Norihito Ueda, Andrew A. Mercer, Stephen B. Fleming, and Lyn M. Wise. "Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2." Journal of General Virology 88, no. 3 (March 1, 2007): 781–91. http://dx.doi.org/10.1099/vir.0.82582-0.
Full textAssareh, Elham, Faramarz Mehrnejad, Kamran Mansouri, Ahmad Reza Esmaeili Rastaghi, Hossein Naderi-Manesh, and S. Mohsen Asghari. "A cyclic peptide reproducing the α1 helix of VEGF-B binds to VEGFR-1 and VEGFR-2 and inhibits angiogenesis and tumor growth." Biochemical Journal 476, no. 4 (February 19, 2019): 645–63. http://dx.doi.org/10.1042/bcj20180823.
Full textHiratsuka, Sachie, Yuki Kataoka, Kazuki Nakao, Kenji Nakamura, Shunichi Morikawa, Satoshi Tanaka, Motoya Katsuki, Yoshiro Maru, and Masabumi Shibuya. "Vascular Endothelial Growth Factor A (VEGF-A) Is Involved in Guidance of VEGF Receptor-Positive Cells to the Anterior Portion of Early Embryos." Molecular and Cellular Biology 25, no. 1 (January 1, 2005): 355–63. http://dx.doi.org/10.1128/mcb.25.1.355-363.2005.
Full textSchechter, Rebecca B., Madhavi Nagilla, Loren Joseph, Poluru L. Reddy, Arun Khattri, Sydeaka Watson, Laura D. Locati, et al. "Genetic profiling of advanced RAI-resistant differentiated thyroid cancer and correlation with axitinib response." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 6066. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.6066.
Full textShibuya, M. "Vascular Endothelial Growth Factor Receptor Family Genes: When Did the Three Genes Phylogenetically Segregate?" Biological Chemistry 383, no. 10 (October 6, 2002): 1573–79. http://dx.doi.org/10.1515/bc.2002.177.
Full textMacy, Margaret E., Deborah DeRyckere, and Lia Gore. "In Vitro Evaluation of the Antitumor Activity of Vandetanib in Pediatric Acute Leukemias." Blood 110, no. 11 (November 16, 2007): 857. http://dx.doi.org/10.1182/blood.v110.11.857.857.
Full textHamada, Koichi, Yuichi Oike, Nobuyuki Takakura, Yasuhiro Ito, Lotta Jussila, Daniel J. Dumont, Kari Alitalo, and Toshio Suda. "VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis." Blood 96, no. 12 (December 1, 2000): 3793–800. http://dx.doi.org/10.1182/blood.v96.12.3793.h8003793_3793_3800.
Full textGao, Minna, Bo Zeng, Xiong Zhang, and Li Yu. "Molecular Mechanism on Inhibition of MB Angiogenesis by Curcumin Blocking the Wnt/β-Catenin and NF-κB Signaling Pathway and Inhibiting the Expression of VEGFs/VEGFRs." Advanced Materials Research 1120-1121 (July 2015): 798–802. http://dx.doi.org/10.4028/www.scientific.net/amr.1120-1121.798.
Full textSecker, Genevieve A., and Natasha L. Harvey. "Regulation of VEGFR Signalling in Lymphatic Vascular Development and Disease: An Update." International Journal of Molecular Sciences 22, no. 14 (July 20, 2021): 7760. http://dx.doi.org/10.3390/ijms22147760.
Full textJi, James W., Feilim Mac Gabhann, and Aleksander S. Popel. "Skeletal muscle VEGF gradients in peripheral arterial disease: simulations of rest and exercise." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 6 (December 2007): H3740—H3749. http://dx.doi.org/10.1152/ajpheart.00009.2007.
Full textVerbiest, Annelies, Benoit Beuselinck, Gabrielle Couchy, Sylvie Job, Aurelien De Reynies, Clément Meiller, Maarten Albersen, et al. "Metastatic clear cell renal cell carcinoma: Proangiogenic gene expression and outcome on sunitinib." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e16085-e16085. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e16085.
Full textHamada, Koichi, Yuichi Oike, Nobuyuki Takakura, Yasuhiro Ito, Lotta Jussila, Daniel J. Dumont, Kari Alitalo, and Toshio Suda. "VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis." Blood 96, no. 12 (December 1, 2000): 3793–800. http://dx.doi.org/10.1182/blood.v96.12.3793.
Full textMouawad, R., C. Soubrane, and D. Khayat. "Prognostic relevance of pretreatment soluble vascular endothelial growth factors (A,C,D) and their receptors (R1, R2, and R3) in advanced melanoma patients." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 8540. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.8540.
Full textSugao, Toshihiko, Yoko Oka, Haruko Tashiro, Ryosuke Shirasaki, Nobu Akiyama, Kazuo Kawasugi, and Naoki Shirafuji. "VEGF Autocrine System Is Demonstrated in Some of Acute Promyelocytic Leukemia Cases: Relationship to WBC Count at the Disease Onset." Blood 114, no. 22 (November 20, 2009): 4127. http://dx.doi.org/10.1182/blood.v114.22.4127.4127.
Full textDonnem, T., S. Al-Saad, K. Al-Shibli, M. P. Delghandi, M. Persson, M. Nilsen, L. T. Busund, and R. M. Bremnes. "Prognostic impact of angiogenic markers in tumor and stromal cells in non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 10596. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.10596.
Full textWimberger, Pauline, Issam Chebouti, Jan Dominik Kuhlmann, Rainer Kimmig, Eberhart Kuhlisch, Robert Lachmann, and Sabine Kasimir-Bauer. "Clinical relevance of VEGF-receptor status in primary ovarian cancer: A pilot study for future biomarker analyses." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 5556. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5556.
Full textGhasemali, Samaneh, Safar Farajnia, Abolfazl Barzegar, Mohammad Rahmati, Babak Negahdari, Leila Rahbarnia, and Hamidreza Yousefi-nodeh. "Rational Design of Anti-Angiogenic Peptides to Inhibit VEGF/VEGFR2 Interactions for Cancer Therapeutics." Anti-Cancer Agents in Medicinal Chemistry 22, no. 10 (June 2022): 2026–35. http://dx.doi.org/10.2174/1871520621666211118104051.
Full textZhang, Cheng, Ning Wang, Hor-Yue Tan, Wei Guo, Sha Li, and Yibin Feng. "Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine." Integrative Cancer Therapies 17, no. 3 (May 28, 2018): 582–601. http://dx.doi.org/10.1177/1534735418775828.
Full textKinget, Lisa, Eduard Roussel, Annelies Verbiest, Maarten Albersen, Cristina Rodríguez-Antona, Osvaldo Graña-Castro, Lucía Inglada-Pérez, et al. "MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma." Cancers 13, no. 12 (June 21, 2021): 3099. http://dx.doi.org/10.3390/cancers13123099.
Full textKilvaer, Thomas K., Andrej Valkov, Sveinung Sorbye, Eivind Smeland, Roy M. Bremnes, Lill-Tove Busund, and Tom Donnem. "Profiling of VEGFs and VEGFRs as Prognostic Factors in Soft Tissue Sarcoma: VEGFR-3 Is an Independent Predictor of Poor Prognosis." PLoS ONE 5, no. 12 (December 14, 2010): e15368. http://dx.doi.org/10.1371/journal.pone.0015368.
Full textShaik, Faheem, Gary Cuthbert, Shervanthi Homer-Vanniasinkam, Stephen Muench, Sreenivasan Ponnambalam, and Michael Harrison. "Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy." Biomolecules 10, no. 12 (December 15, 2020): 1673. http://dx.doi.org/10.3390/biom10121673.
Full textYang, Yan, Peng Xie, Yarden Opatowsky, and Joseph Schlessinger. "Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling." Proceedings of the National Academy of Sciences 107, no. 5 (January 11, 2010): 1906–11. http://dx.doi.org/10.1073/pnas.0914052107.
Full textKorchagina, A. A., S. A. Shein, O. I. Gurina, and V. P. Chekhonin. "VEGFRS IN NEOPLASTIC ANGIOGENESIS AND PROSPECTS FOR THERAPY ОF BRAIN TUMORS." Annals of the Russian academy of medical sciences 68, no. 11 (November 12, 2013): 104–14. http://dx.doi.org/10.15690/vramn.v68i11.851.
Full textTrapiella-Alfonso, Laura, Sylvain Broussy, Wang-Qing Liu, Michel Vidal, Edouard Lecarpentier, Vassilis Tsatsaris, and Nathalie Gagey-Eilstein. "Colorimetric immunoassays for the screening and specificity evaluation of molecules disturbing VEGFs/VEGFRs interactions." Analytical Biochemistry 544 (March 2018): 114–20. http://dx.doi.org/10.1016/j.ab.2017.12.029.
Full textAnkita, P., Z. Romana, and A. Sanjar. "Benzimidazoles as Anti-VEGFRs: A Review." International Journal for Pharmaceutical Research Scholars 7, no. 1 (2018): 82–95. http://dx.doi.org/10.31638/ijprs.v7.i1.00013.
Full textHamerlik, Petra, Justin D. Lathia, Rikke Rasmussen, Qiulian Wu, Jirina Bartkova, MyungHee Lee, Pavel Moudry, et al. "Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth." Journal of Experimental Medicine 209, no. 3 (March 5, 2012): 507–20. http://dx.doi.org/10.1084/jem.20111424.
Full textAlarcón, Tomás, and Karen M. Page. "Mathematical models of the VEGF receptor and its role in cancer therapy." Journal of The Royal Society Interface 4, no. 13 (November 21, 2006): 283–304. http://dx.doi.org/10.1098/rsif.2006.0170.
Full textRobinson, C. J., and S. E. Stringer. "The splice variants of vascular endothelial growth factor (VEGF) and their receptors." Journal of Cell Science 114, no. 5 (March 1, 2001): 853–65. http://dx.doi.org/10.1242/jcs.114.5.853.
Full textZhao, Bin, Peimin Yang, Jing Yang, and Duan Cai. "A Randomized Trial of Somatostatin to Regulate the VEGFs/VEGFRs in Patients with Gastric Cancer." Hepatogastroenterology 58, no. 109 (August 2011): 1425–30. http://dx.doi.org/10.5754/hge10749.
Full textCarrillo Arias, F., E. Carrillo de Santa Pau, E. Pérez Rodríguez, M. Toledo Lobo',, I. Sánchez Hernandez, G. Muñoz Molina, I. Muguruza Trueba, P. Navio Martin, S. Dominguez Reboiras, and E. Caso Peláez. "P-013 Expression of VEGFs and VEGFRs according to TNMc and TNMq. Reality or fiction?" Lung Cancer 49 (July 2005): S118. http://dx.doi.org/10.1016/s0169-5002(05)80507-0.
Full textCarrillo de Santa Pau, E., M. Toledo Lobo, E. Caso Peláez, E. Pérez Rodríguez, I. Sánchez Hernández, G. Muñoz Molina, I. Muguruza Trueba, S. Sacristán, G. Gómez López, and F. Carillo Arias. "P-014 Discriminate capacity of VEGFs and VEGFRs in lung cancer. Arethe different subtypes outstanding?" Lung Cancer 49 (July 2005): S118—S119. http://dx.doi.org/10.1016/s0169-5002(05)80508-2.
Full textWu, Florence T. H., Marianne O. Stefanini, Feilim Mac Gabhann, Christopher D. Kontos, Brian H. Annex, and Aleksander S. Popel. "Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport." Physiological Genomics 38, no. 1 (June 2009): 29–41. http://dx.doi.org/10.1152/physiolgenomics.00031.2009.
Full textMasłowska, Katarzyna, Paweł Krzysztof Halik, Dagmara Tymecka, Aleksandra Misicka, and Ewa Gniazdowska. "The Role of VEGF Receptors as Molecular Target in Nuclear Medicine for Cancer Diagnosis and Combination Therapy." Cancers 13, no. 5 (March 3, 2021): 1072. http://dx.doi.org/10.3390/cancers13051072.
Full textStevens, Megan, and Sebastian Oltean. "Modulation of Receptor Tyrosine Kinase Activity through Alternative Splicing of Ligands and Receptors in the VEGF-A/VEGFR Axis." Cells 8, no. 4 (March 28, 2019): 288. http://dx.doi.org/10.3390/cells8040288.
Full textVerdes, Doina, Roxana Popescu, Smaranda Rodica Gotia, Laura Gotia, Marioara Nicoleta Filimon, and Theodoros Karabitsakos. "VEGF and VEGFRs expression in psoriasis lesions." Current Opinion in Biotechnology 22 (September 2011): S114. http://dx.doi.org/10.1016/j.copbio.2011.05.367.
Full textImoukhuede, P. I., Ayotunde O. Dokun, Brian H. Annex, and Aleksander S. Popel. "Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia." American Journal of Physiology-Heart and Circulatory Physiology 304, no. 8 (April 15, 2013): H1085—H1093. http://dx.doi.org/10.1152/ajpheart.00514.2012.
Full textReumann, Marie K., Turya Nair, Olga Strachna, Adele L. Boskey, and Philipp Mayer-Kuckuk. "Production of VEGF receptor 1 and 2 mRNA and protein during endochondral bone repair is differential and healing phase specific." Journal of Applied Physiology 109, no. 6 (December 2010): 1930–38. http://dx.doi.org/10.1152/japplphysiol.00839.2010.
Full textDurante, Cosimo, Giovanni Tallini, Efisio Puxeddu, Marialuisa Sponziello, Sonia Moretti, Claudia Ligorio, Antonio Cavaliere, et al. "BRAFV600E mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas." European Journal of Endocrinology 165, no. 3 (September 2011): 455–63. http://dx.doi.org/10.1530/eje-11-0283.
Full textBruns, Alexander F., Leyuan Bao, John H. Walker, and Sreenivasan Ponnambalam. "VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis." Biochemical Society Transactions 37, no. 6 (November 19, 2009): 1193–97. http://dx.doi.org/10.1042/bst0371193.
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