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1

International Symposium on Viruses with Fungal Vectors (1987 St. Andrews University). Viruses with fungal vectors. Wellesbourne, Warwick: Association of Applied Biologists, 1988.

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2

Mukhopadhyay, S. Plant virus, vector epidemiology and management. Enfield, NH: Science Publishers, 2010.

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3

Mukhopadhyay, S. Plant virus, vector epidemiology and management. Enfield, NH: Science Publishers, 2010.

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4

Mukhopadhyay, S. Plant virus, vector epidemiology and management. Enfield, NH: Science Publishers, 2010.

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5

National Academy of Sciences Colloquium on Genetic Engineering of Viruses and of Virus Vectors (1996 Irvine, Calif.). National Academy of Sciences Colloquium: Genetic Engineering of Viruses and of Virus Vectors. Washington, D.C: National Academy of Sciences, 1996.

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6

Basu, A. N. Bemisia tabaci (Gennadius): Crop pest and principal whitefly vector of plant viruses. Boulder: Westview Press, 1995.

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7

Brambilla, Riccardo. Viral vector approaches in neurobiology and brain diseases. New York: Humana Press, 2013.

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8

F, Brown D. J., ed. Nematode vectors of plant viruses. New York: CAB International, 1997.

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9

Nagai, Yoshiyuki, ed. Sendai Virus Vector. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9.

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10

Ando, Hirotaro. Viruses in vectors: Transovarial passage and retention. St. Paul, Minn., USA (3340 Pilot Knob Rd., St. Paul 55121): Phytopathological Society, 1986.

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11

Workshop on Vaccinia Viruses as Vectors for Vaccine Antigens (1984 Chevy Chase). Vaccinia Viruses as vectors for vaccine antigens. Edited by Quinnan Gerald V. New York: Elsevier, 1985.

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12

Castle, Michael J., ed. Adeno-Associated Virus Vectors. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9139-6.

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13

Chan, C. K. Aphid-transmitted viruses and their vectors of the world. Vancouver: Research Branch, Agriculture Canada, 1991.

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14

Viral vectors for gene therapy: Methods and protocols. New York: Humana Press, 2011.

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15

Nebbache, Salim. The virus-vector relationship of maize streak virus with Cicadulina leafhoppers. Norwich: University ofEast Anglia, 1988.

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16

Decraemer, W. The Family Trichodoridae: Stubby Root and Virus Vector Nematodes. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8482-1.

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17

Decraemer, W. The family Trichodoridae: Stubby root and virus vector nematodes. Dordrecht: Kluwer Academic Publishers, 1995.

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18

V, Quinnan Gerald, ed. Vaccinia viruses as vectors for vaccine antigens: Proceedings of the Workshop on Vaccinia Viruses as Vectors for Vaccine Antigens, held November 13-14, 1984, in Chevy Chase, Maryland, U.S.A. New York: Elsevier, 1985.

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19

Berns, Kenneth I., and Catherine Giraud, eds. Adeno-Associated Virus (AAV) Vectors in Gene Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80207-2.

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20

Doerfler, Walter, and Petra Böhm, eds. Adenoviruses: Model and Vectors in Virus-Host Interactions. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05597-7.

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21

Doerfler, Walter, and Petra Böhm, eds. Adenoviruses: Model and Vectors in Virus-Host Interactions. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-05599-1.

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22

Ghose, Abhijit. The canarypox virus ALVAC as a vector in cancer gene therapy. Ottawa: National Library of Canada, 1999.

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23

Das, Bina Pani. Mosquito Vectors of Japanese Encephalitis Virus from Northern India. India: Springer India, 2013. http://dx.doi.org/10.1007/978-81-322-0861-7.

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24

Danielová, Vlasta. Relationships of mosquitoes to Ťahyňa virus as determinant factors of its circulation in nature. Prague: Academia, Publishing House of the Czechoslovak Academy of Sciences, 1992.

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25

Chapple, Susan Dorothy Jane. Improving baculovirus expression vectors by modulating the synthesis of an essential virus protein. Oxford: Oxford Brookes University, 1998.

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26

Alberti, Gerd, and Elliot W. Kitajima. Anatomy and fine structure of Brevipalpus mites (Tenuipalpidae)--economically important plant-virus vectors. Stuttgart: Schweizerbart Science Publishers, 2014.

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27

Batista, Maria de Fatima. Studies of barley yellow mosaic virus (BaYMV) - Streatley (recently renamed barley mild mosaic virus) and its diagnosis in plants, vector and soil. Birmingham: University of Birmingham, 1991.

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28

Lee-Shanok, Richard. Construction and preliminary characterization of papaya mosaic virus as an expression vector for the presentation of foreign epitopes. Ottawa: National Library of Canada, 1999.

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29

Mitchison, Hannah Margaret. The use of expression vectors and recombinant virus in the study of adenovirus transforming proteins. Birmingham: University of Birmingham, 1991.

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30

T, Plumb R., ed. Plant virus vector interactions. San Diego: Academic Press, 2002.

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31

Drake, John M., Michael Bonsall, and Michael Strand, eds. Population Biology of Vector-Borne Diseases. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198853244.001.0001.

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Population Biology of Vector-Borne Diseases is the first comprehensive survey of this rapidly developing field. The chapter topics provide an up-to-date presentation of classical concepts, reviews of emerging trends, synthesis of existing knowledge, and a prospective agenda for future research. The contributions offer authoritative and international perspectives from leading thinkers in the field. The dynamics of vector-borne diseases are far more intrinsically ecological compared with their directly transmitted equivalents. The environmental dependence of ectotherm vectors means that vector-borne pathogens are acutely sensitive to changing environmental conditions. Although perennially important vector-borne diseases such as malaria and dengue have deeply informed our understanding of vector-borne diseases, recent emerging viruses such as West Nile virus, Chikungunya virus, and Zika virus have generated new scientific questions and practical problems. The study of vector-borne disease has been a particularly rich source of ecological questions, while ecological theory has provided the conceptual tools for thinking about their evolution, transmission, and spatial extent.
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32

Crawford, Dorothy H. Viruses: A Very Short Introduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/actrade/9780198811718.001.0001.

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Viruses: A Very Short Introduction outlines the origins, structure, and method of infection of a vast variety of viruses and demonstrates how clever these entities appear to be. It explains the vital role viruses play in the ocean’s delicate ecosystem and discusses the impact of global warming, which is increasing the range of vector-transmitted viruses such as dengue, yellow fever, and West Nile virus. The recent Ebola and Zika epidemics, as well as Middle East Respiratory Syndrome, are also discussed. Can we ever live in harmony with viruses? This VSI considers the ways in which we may need to adapt to prevent emerging viruses with devastating consequences.
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33

F, Harris Kerry, Smith Oney P. 1954-, and Duffus James E, eds. Virus-insect-plant interactions. San Diego, Calif: Academic, 2001.

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34

Li, Guoxuan. The characterization and cloning of the RNA of a vector-nonspecific isolate of barley yellow dwarf virus commonly found in wheat in Washington State. 1990.

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35

Plumb, R. T. Interactions between Plant Viruses and their Vectors (Advances in Botanical Research, Volume 36) (Advances in Botanical Research). Academic Press, 2002.

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36

Plumb, R. T. Interactions between Plant Viruses and their Vectors (Advances in Botanical Research, Volume 36) (Advances in Botanical Research). Academic Press, 2002.

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37

C, Asher M. J., Cooper J. I, and Association of Applied Biologists, eds. Viruses with fungal vectors: Proceedings of a conference at the University of St. Andrews, 25-27 August, 1987. Wellesbourne, Warwick: Association of Applied Biologists, 1988.

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38

Gould, E. A. Mosquito-borne arboviruses. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0039.

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The arboviruses are all single-stranded RNA viruses, although they belong to four different viral families. Several important human pathogens belong to the mosquito-borne arboviruses including yellow fever, Japanese encephalitis and Rift Valley Fever. They cause a wide range of illnesses from unrecognised infection to severe systemic disease with hemorrhagic complications and encephalitis with a high mortality similar range of illnesses is seen in infected animals.Arboviruses have several unique characteristics, these include; an ability to infect and be transmitted by mosquitos, ticks, midges, sand flies, bugs, fleas, blackflies and horseflies. They infect vertebrate hosts which may amplify virus for invertebrate vectors that feed on infected vertebrates. An ability to replicate in anthropods, with little pathology and in vertebrates often with significant pathology. Many arboviruses are Zoonotic.Control methods depend on the epidemiology of particular viruses, but epidemic vector control through control of insect breeding sites and the use of insecticide spraying have been successfully used in the past. Effective vaccines are available for yellow fever and Japanese encephalitis.
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39

L, Hefferon Kathleen, ed. Virus expression vectors. Tribandrum: Transworld Research Network, 2007.

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40

Matthews, Philippa C. Tropical Medicine Notebook. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737773.001.0001.

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The Tropical Medicine Notebook provides a concise overview of the key topics in tropical medicine using short notes, diagrams, maps, and tables. The book is divided into eight sections. The first five cover infections caused by bacteria, viruses, fungi, protozoa, and helminths. The following three present the topics of vector biology, disease syndromes, and envenomation. A final section listing relevant guidelines, publications, and other resources guides the reader to more detailed information when required.
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41

Mukhopadhyay, S. Plant Virus, Vector. Taylor & Francis Group, 2010.

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42

Mukhopadhyay, S. Plant Virus, Vector. Taylor & Francis Group, 2010.

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43

Mukhopadhyay, S. Plant Virus, Vector. Taylor & Francis Group, 2017.

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44

Yakov, Gluzman, Hughes Stephen H, and Cold Spring Harbor Laboratory, eds. Viral vectors. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory, 1988.

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45

Flint, S. Jane, and Glen R. Nemerow. Human Adenoviruses: From Villains to Vectors. World Scientific Publishing Co Pte Ltd, 2016.

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46

Grant, Warren, and Martin Scott-Brown. Principles of oncogenesis. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0322.

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It is obvious that the process of developing cancer—oncogenesis—is a multistep process. We know that smoking, obesity, and a family history are strong independent predictors of developing malignancy; yet, in clinics, we often see that some heavy smokers live into their nineties and that some people with close relatives affected by cancer spend many years worrying about a disease that, in the end, they never contract. For many centuries scientists have struggled to understand the process that make cancer cells different from normal cells. There were those in ancient times who believed that tumours were attributable to acts of the gods. Hippocrates suggested that cancer resulted from an imbalance between the black humour that came from the spleen, and the other three humours: blood, phlegm, and bile. It is only in the last 100 years that biologists have been able to characterize some of the pathways that lead to the uncontrolled replication seen in cancer, and subsequently examine exactly how these pathways evolve. The rampant nature by which cancer invades local and distant tissues, as well its apparent ability to spread between related individuals led some, such as Peyton Rous in 1910, to suggest that cancer was an infectious condition. He was awarded a Nobel Prize in 1966 for the 50 years of work into investigating a link between sarcoma in chickens and a retrovirus that became known as Rous sarcoma virus. He had shown how retroviruses are able to integrate sequences of DNA coding for errors in cellular replication control (oncogenes) by introducing into the human cell viral RNA together with a reverse transcriptase. Viruses are now implicated in many cancers, and in countries where viruses such as HIV and EBV are endemic, the high incidence of malignancies such as Kaposi’s sarcoma and Burkitt’s lymphoma is likely to be directly related. There are several families of viruses associated with cancer, broadly classed into DNA viruses, which mutate human genes using their own DNA, and retroviruses, like Rous sarcoma virus, which insert viral RNA into the cell, where it is then transcribed into genes. This link with viruses has not only led to an understanding that cancer originates from genetic mutations, but has also become a key focus in the design of new anticancer therapies. Traditional chemotherapies either alter DNA structure (as with cisplatin) or inhibit production of its component parts (as with 5-fluorouracil.) These broad-spectrum agents have many and varied side effects, largely due to their non-specific activity on replicating DNA throughout the body, not just in tumour cells. New vaccine therapies utilizing gene-coding viruses aim to restore deficient biological pathways or inhibit mutated ones specific to tumour cells. The hope is that these gene therapies will be effective and easily tolerated by patients, but development is currently progressing with caution. In a trial in France of ten children suffering from X-linked severe combined immunodeficiency and who were injected with a vector that coded for the gene product they lacked, two of the children subsequently died from leukaemia. Further analysis confirmed that the DNA from the viral vector had become integrated into an existing, but normally inactive, proto-oncogene, LM02, triggering its conversion into an active oncogene, and the development of life-threatening malignancy. To understand how a tiny change in genetic structure could lead to such tragic consequences, we need to understand the molecular biology of the cell and, in particular, to pay attention to the pathways of growth regulation that are necessary in all mammalian cell populations. Errors in six key regulatory pathways are known as the ‘hallmarks of cancer’ and will be discussed in the rest of this chapter.
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47

Aphid: A Virus Vector. Amer Phytopathological Society, 2004.

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48

Bartlett, Jeffrey S. Aav Virus and Vector Protocols. Humana Press, 2006.

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49

L, Collins Mary K., ed. Practical molecular virology: Viral vectors for gene expression. Clifton, N.J: Humana Press, 1991.

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50

Valenzano), International Plant Virus Epidemiology Symposium (5th 1992. Viruses, vectors and the environment: 5th International Plant Virus Epidemiology Symposium ... 27-31 July 1992. [The Symposium], 1992.

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