Journal articles: 'Vcacl'

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Noor, Shazia, Hadeed Ashraf, Muhammad Sultan, and Zahid Mahmood Khan. "Evaporative Cooling Options for Building Air-Conditioning: A Comprehensive Study for Climatic Conditions of Multan (Pakistan)." Energies 13, no. 12 (June 12, 2020): 3061. http://dx.doi.org/10.3390/en13123061.

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This study provides comprehensive details of evaporative cooling options for building air-conditioning (AC) in Multan (Pakistan). Standalone evaporative cooling and standalone vapor compression AC (VCAC) systems are commonly used in Pakistan. Therefore, seven AC system configurations comprising of direct evaporative cooling (DEC), indirect evaporative cooling (IEC), VCAC, and their possible combinations, are explored for the climatic conditions of Multan. The study aims to explore the optimum AC system configuration for the building AC from the viewpoints of cooling capacity, system performance, energy consumption, and CO2 emissions. A simulation model was designed in DesignBuilder and simulated using EnergyPlus in order to optimize the applicability of the proposed systems. The standalone VCAC and hybrid IEC-VCAC & IEC-DEC-VCAC system configurations could achieve the desired human thermal comfort. The standalone DEC resulted in a maximum COP of 4.5, whereas, it was 2.1 in case of the hybrid IEC-DEC-VCAC system. The hybrid IEC-DEC-VCAC system achieved maximum temperature gradient (21 °C) and relatively less CO2 emissions as compared to standalone VCAC. In addition, it provided maximum cooling capacity (184 kW for work input of 100 kW), which is 85% higher than the standalone DEC system. Furthermore, it achieved neutral to slightly cool human thermal comfort i.e., 0 to −1 predicted mean vote and 30% of predicted percentage dissatisfied. Thus, the study concludes the hybrid IEC-DEC-VCAC as an optimum configuration for building AC in Multan.

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Yozgat, Can Yilmaz, Yanki Celik Yilmazer, and Yilmaz Yozgat. "Pulmonary Atresia with Intact Ventricular Septum associated with Ventriculo-Coronary Arterial Communication in a Fetus at 21 Weeks of Gestation." Case Reports in Obstetrics and Gynecology 2020 (July 15, 2020): 1–3. http://dx.doi.org/10.1155/2020/7581483.

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Pulmonary atresia with the intact ventricular septum (PA-IVS) is a rare anomaly that has an absent communication between the right ventricle and pulmonary arterial circulation. PA-IVS has a hypoplastic and hypokinetic and thickened right ventricle with the intact ventricular septum. It can be diagnosed with PA-IVS in routine obstetric ultrasound examination because the four-chamber view of PA-IVS is generally abnormal. The size of the right ventricular cavity is proportional to the Z value of the diameter of the tricuspid valve. The essential associated cardiac finding of PA-IVS is ventricular-coronary arterial communications (VCAC). The hypertensive RV forces blood through the intramyocardial sinusoids with continuous fistulous contact with the epicardial branches of RCA. It is called the VCAC. A color Doppler can detect VCAC due to its location in the pericardium along the coronary artery. If patients have VCAC and tricuspid Z score below -4, all of these conditions are infallible signs of high mortality rates in their fetal or postnatal lives. Our aim in presenting this case is to remind perinatologists if they detect an abnormal four-chamber view of the fetus’s heart, they should also carefully examine whether VCAC exists. Herein, we report a case of PA-IVS and VCAC at 21 weeks’ gestation with fetal echocardiographic images.

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Hoyle, Victoria, Madison T. Flasco, Jiyeong Choi, Elizabeth J. Cieniewicz, Heather McLane, Keith Perry, Gerald Dangl, et al. "Transmission of Grapevine Red Blotch Virus by Spissistilus festinus [Say, 1830] (Hemiptera: Membracidae) between Free-Living Vines and Vitis vinifera ‘Cabernet Franc’." Viruses 14, no. 6 (May 26, 2022): 1156. http://dx.doi.org/10.3390/v14061156.

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Grapevine red blotch disease emerged within the past decade, disrupting North American vine stock production and vineyard profitability. Our understanding of how grapevine red blotch virus (GRBV), the causal agent of the disease, interacts with its Vitis hosts and insect vector, Spissistilus festinus, is limited. Here, we studied the capabilities of S. festinus to transmit GRBV from and to free-living vines, identified as first-generation hybrids of V. californica and V. vinifera ‘Sauvignon blanc’ (Vcal hybrids), and to and from V. vinifera ‘Cabernet franc’ (Vvin Cf) vines. The transmission rate of GRBV was high from infected Vcal hybrid vines to healthy Vcal hybrid vines (77%, 10 of 13) and from infected Vvin Cf vines to healthy Vcal hybrid vines (100%, 3 of 3). In contrast, the transmission rate of GRBV was low from infected Vcal hybrid vines to healthy Vvin Cf vines (15%, 2 of 13), and from infected Vvin Cf vines to healthy Vvin Cf vines (19%, 5 of 27). No association was found between transmission rates and GRBV titer in donor vines used in transmission assays, but the virus titer was higher in the recipient leaves of Vcal hybrid vines compared with recipient leaves of Vvin Cf vines. The transmission of GRBV from infected Vcal hybrid vines was also determined to be trans-stadial. Altogether, our findings revealed that free-living vines can be a source for the GRBV inoculum that is transmissible by S. festinus to other free-living vines and a wine grape cultivar, illustrating the interconnected roles of the two virus hosts in riparian areas and commercial vineyards, respectively, for virus spread. These new insights into red blotch disease epidemiology will inform the implementation of disease management strategies.

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Blake, Damian, and David Gallagher. "Examining the Development of the Victorian Certificate of Applied Learning and Its Implications for Schools and Teacher Education in Australia." Journal of Applied Learning in Higher Education 01 (2009): 49–71. http://dx.doi.org/10.57186/jalhe_2009_v1a3p49-71.

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The Victorian Certificate of Applied Learning (VCAL) is a very successful senior secondary school qualification introduced in the Australian state of Victoria in 2002. Applied learning in the VCAL engages senior students in a combination of work-based learning, service-learning, and project-based learning and aims to provide them with the skills, knowledge, and attitudes to make informed choices regarding pathways to work and further education. The program has enjoyed rapid growth and its system-wide adoption by Victorian secondary schools, Technical and Further Education (TAFE) institutions, Registered Training Organizations (RTOs), and Adult and Community Education (ACE) providers has broadened significantly the range of senior schooling pathway options for young people. This paper will examine reasons for developing an applied learning senior secondary certificate and its rapid growth in Victoria since 2002. The authors draw on a number of case studies to profile the unique nature of applied learning in the VCAL, including its dimensions of service learning, work-based learning, and project-based learning. These case studies are also used to discuss a number of implications that have emerged from the use of applied learning in the VCAL, including approaches to teaching and assessment that will support applied learning and the development of new partnerships between VCAL providers and community partners. Finally, the paper considers significant implications the VCAL has created for teacher education in Victoria by discussing the new Graduate Diploma of Education (Applied Learning) developed by Deakin University.

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Guzman Barragan, Blanca Lisseth. "Contextos locales de la vigilancia de la calidad del agua para consumo humano en de los países de América Latina: Brasil y Colombia." Revista de Salud Pública 17, no. 6 (February 19, 2016): 961–72. http://dx.doi.org/10.15446/rsap.v17n6.40977.

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Analizar comparativamente los sistemas nacionales de vigilancia de la calidad del agua para consumo humano (VCACH) de Brasil y Colombia, con el fin de comprender como están organizadas las prácticas en estos países, sus límites y posibilidades.Métodos: Se utilizó la metodología Cross Nacional, mediante el análisis documental de fuentes secundarias, las cuales fueron obtenidas a través de las instituciones responsables y páginas oficiales. Con el propósito de discutir las convergencias y divergencias entre los dos sistemas, considerando las directrices de la Organización Mundial da Salud. Resultados: Los marcos legales de la VCACH en Brasil y Colombia comienzan a definirse en la década 70-80, coincidiendo con la visibilidad internacional de esta temática. Las prácticas de VCACH en el Brasil estuvieron definidas y organizadas en un programa nacional, lo que solamente se está dando en Colombia recientemente. Las actuales legislaciones avanzan en los componentes que orientan las prácticas de vigilancia, por ejemplo, incorporación de metodologías de evaluación de riesgo. La legislación colombiana establece la regulación de la prestación de los servicios de abastecimiento de agua, aspecto no contemplado en la legislación brasilera. Elementos como descentralización, intersectorialidad, universalidad y el derecho a información son contemplados en las legislaciones de ambos países, aunque las acciones de VCACH necesiten avanzar para la efectiva operatividad de los mismos. Conclusiones: Brasil y Colombia presentan semejanzas en los procesos de definición de la VCACH, estando en momentos distintos de implementación de las acciones de VCACH. Estas son necesarias para garantizar los derechos humanos relacionados con la preservación de ambiente, así como la universalidad del acceso a agua potable en cantidades y en calidad adecuadas, contribuyendo en la promoción de la salud.

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Jain, Sfoorti. "Credit Pit Detection in Subordinate Securities: A French Perspective." Ushus - Journal of Business Management 18, no. 3 (July 1, 2019): 65–85. http://dx.doi.org/10.12725/ujbm.48.6.

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The purpose of this research is to prepare a predictive model for identifying credit crisis using an artificial neural network. The paper also aims to find out the driver and driven relationship between various financial instruments like CDS, FRA, IRS, and the Volatility index (VCAC) and government securities for France. The model, thus, is directed towards finding a threshold for credit pit events and linking various events corresponding to that dates where the threshold is breached to validate the accuracy and usefulness of the model. From the research, it is found that for France, the CDS-FRA-VCAC model derives the threshold for VCAC to indicate the probability of credit crisis or financial market crash. It is also found that sovereign bonds have a huge impact on France economy including various derivatives. This is probably why the Eurozone debt crisis impacted France much more than the 2008 financial crash.

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Miller-Kittrell, Mindy, Jiqing Sai, Mark Penfold, Ann Richmond, and Tim E. Sparer. "Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1CCMV." Virology 364, no. 2 (August 2007): 454–65. http://dx.doi.org/10.1016/j.virol.2007.03.002.

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Choi, Young Bong, and John Nicholas. "Autocrine and Paracrine Promotion of Cell Survival and Virus Replication by Human Herpesvirus 8 Chemokines." Journal of Virology 82, no. 13 (April 23, 2008): 6501–13. http://dx.doi.org/10.1128/jvi.02396-07.

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ABSTRACT Human herpesvirus 8 (HHV-8), which is associated with the endothelial tumor Kaposi's sarcoma, encodes three CC/β-chemokines. These are expressed early during productive (lytic) infection and are believed to be involved in immune evasion, in addition to viral pathogenesis via induction of angiogenic cytokines. Here we report that two of the HHV-8 chemokines, CCR8 agonists vCCL-1 and vCCL-2, have direct effects on endothelial survival and virus replication. The v-chemokines stimulated virus replication when added to infected cultures exogenously, and CCR8 knockdown absent v-chemokine supplementation inhibited virus production, indicative of autocrine effects of endogenously produced vCCLs. This was verified and proreplication functions of each chemokine were demonstrated via shRNA-mediated vCCL depletion. The v-chemokines inhibited expression of lytic cycle-induced proapoptotic protein Bim, RNA interference-mediated suppression of which mimicked v-chemokine proreplication functions. Our data show for the first time that the v-chemokines have direct effects on virus biology, independently of their postulated immune evasion functions, and suggest that in vivo the v-chemokines might play direct roles in Kaposi's sarcomagenesis via paracrine prosurvival signaling.

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Georgiou, Gerasimos Odysseas, Francesco Tarallo, Enrico Marchetti, and Sergio Bizzarro. "Overview of the Effect of Different Regenerative Materials in Class II Furcation Defects in Periodontal Patients." Materials 15, no. 9 (April 28, 2022): 3194. http://dx.doi.org/10.3390/ma15093194.

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The aim of this review was to give an overview of the outcomes of the use of different regenerative materials to treat molars with class II furcation defects in patients with periodontitis in comparison with open flap debridement (OFD). A search of five databases (PubMed-Medline, Embase, Cochrane, Scopus and Web of Science) was conducted up to and including January 2022. According to the PICOS guidelines, only randomized control trials (S) considering periodontal patients with at least one molar with a class II furcation involvement (P) treated with regenerative materials (I) in comparison to OFD as control treatment (C) and a minimum follow-up period of 6 months were included. Vertical clinical attachment level (VCAL) was considered as the primary outcome (O), while horizontal clinical attachment level (HCAL), horizontal probing depth (HPD) and vertical probing depth (VPD) were considered as secondary outcomes. The search through the databases initially identified 1315 articles. Only 25 of them met the eligibility criteria and were included. The studies were grouped in four macro-categories according to the material used: absorbable and non-absorbable membranes, blood derivatives and a combination of different materials. The greater part of the included studies reported a statistically significant difference in using regenerative materials when compared to OFD. The blood derivatives groups reported a range of mean changes in VCAL of 0.86–4.6 mm, absorbable membrane groups reported −0.6–3.75 mm, non-absorbable membranes groups reported −2.47–4.1 mm, multiple materials groups reported −1.5–4.87 mm and enamel matrix derivatives reported a mean change in VCAL of 1.45 mm. OFD showed a range of mean VCAL changes of −1.86–2.81 mm. Although no statistical analysis was performed, the use of regenerative materials may be considered moderately beneficial in the treatment of molars with grade II furcation involvement. However, the substantial heterogeneity in the protocols’ design does not allow us to draw definitive conclusions. In addition, low levels of evidence for morbidity and patient-centered outcomes were reported.

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Hirsz, Marta, and Krystyna Nagrodzka-Godycka. "Verification of selected calculation methods regarding shear strength in beams without web reinforcement." MATEC Web of Conferences 219 (2018): 03015. http://dx.doi.org/10.1051/matecconf/201821903015.

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The purpose of the article was to compare selected calculation methods regarding shear strength in reinforced concrete beams without web reinforcement. Several calculation methods were tested. This included codes: PN-EN 1992-1-1:2008, ACI 318-14 and fib Model Code for Concrete Structures 2010. The analysis also consists of authorial methods published in technical literature. Calculations of shear strengths were made based on experimental works found in literature. The shear strength ratios Vtest/Vcalc were chosen to be the yardstick of comparison, where Vtest is the experimental shear strength and Vcalc is the calculated shear strength. A wide range of variables including shear span/depth ratio, compressive strength of concrete, longitudinal steel percentage helped to verify the applicability of calculation methods. Although most of authorial techniques proved to be unstable, they succeeded to show that codes’ formulas for shear strength may still be improved. The presented article is a part of Authors’ long term research in the matter and a new chapter of their study now concerning beams without web reinforcement.

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Tarallo, Francesco, Leonardo Mancini, Luciano Pitzurra, Sergio Bizzarro, Michele Tepedino, and Enrico Marchetti. "Use of Platelet-Rich Fibrin in the Treatment of Grade 2 Furcation Defects: Systematic Review and Meta-Analysis." Journal of Clinical Medicine 9, no. 7 (July 3, 2020): 2104. http://dx.doi.org/10.3390/jcm9072104.

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In periodontitis patients, furcation defects are crucial sites to regenerate due to their complex anatomy. Various modern surgical techniques and use of biomaterials have been suggested in the literature. Among all, platelet-rich fibrin (PRF) has potential in tissue regeneration thanks to its role in the release of growth factors. Therefore, the purpose of this study was to evaluate the beneficial effect of the addition of PRF to open flap debridement (OFD) or as an adjuvant to other biomaterials such as bone grafts in the treatment of grade 2 mandibular furcation defects. Systematic research was carried out on the databases Medline, Scopus, Embase, and Cochrane Library and registered on PROSPERO (CRD42020167662). According to the PICO guidelines by Cochrane, randomized trials and prospective non-randomized trials were evaluated, with a minimum follow-up period of 6 months. The inclusion criteria were the absence of systemic diseases, non-smoking patients, and a population aged from 18 to 65 years. Vertical pocket probing depth (PPD), vertical clinical attachment level (VCAL), and gingival recession (REC) were the primary outcomes. Vertical furcation depth (VFD), and the percentage of bone defect fill (%v-BDF) were considered as secondary outcomes. A meta-analysis of the primary and secondary outcomes was performed. Publication bias was assessed through a funnel plot. Eighty-four articles were initially extracted. Eight randomized clinical trials were analyzed according to the exclusion and inclusion criteria. The Quality assessment instrument (QAI) revealed four articles at low risk of bias, one at moderate, and three at high risk of bias. The metanalysis showed significant data regarding PPD, VCAL, VFD and %v-BDF in the comparison between PRF + OFD vs. OFD alone. The adjunct of PRF to a bone graft showed a significant difference for VCAL and a not statistically significant result for the other involved parameters. In conclusion, the adjunctive use of PRF to OFD seems to enhance the periodontal regeneration in the treatment of grade 2 furcation defects. The combination of PRF and bone graft did not show better clinical results, except for VCAL, although the amount of literature with low risk of bias is scarce. Further well-designed studies to evaluate the combination of these two materials are therefore needed.

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Ganim, Zoe, and Erica Frydenberg. "Attitudes to School, Coping,Wellbeing and Stress: An Examination of VCAL Students." Australian Educational and Developmental Psychologist 23, no. 1 (2006): 7–26. http://dx.doi.org/10.1017/s0816512200028844.

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AbstractOne hundred and fifty-seven students (aged 15 to 19 years) enrolled in the Victorian Certificate of Applied Learning (VCAL) program completed the Adolescent Coping Scale (ACS), and measures of school-related stress, attitudes to school and wellbeing. In general, VCAL students reported a positive attitude to school, high levels of wellbeing, low levels of school-related stress, and used a wide range of coping strategies. Gender differences and attitudinal differences were found in relation to coping strategies used, wellbeing, and stress. Discriminant analysis indicated that for females, low levels of school-related stress and frequent use of the ‘work hard’coping strategy significantly predicted a positive attitude to school, while for males high levels of wellbeing, and the frequent use of ‘work hard’, ‘focus on the positive’, and minimal use of ‘tension reduction’ predicted positive attitudes to school. The findings are discussed in light of current research and recommendations for interventions are proposed.

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Bailey, Rowena, Greg Williams, Irem Sahin, and Marcelle Cacciattolo. "The VCAL Experience: Unpacking Innovative Teaching and Learning Strategies." International Journal of Interdisciplinary Social Sciences: Annual Review 2, no. 2 (2007): 207–16. http://dx.doi.org/10.18848/1833-1882/cgp/v02i02/52255.

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Alcendor, Donald J., Jianchao Zong, Aidan Dolan, Derek Gatherer, Andrew J. Davison, and Gary S. Hayward. "Patterns of divergence in the vCXCL and vGPCR gene clusters in primate cytomegalovirus genomes." Virology 395, no. 1 (December 2009): 21–32. http://dx.doi.org/10.1016/j.virol.2009.09.002.

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Heo, Jinho, Pranay Dogra, Tom J. Masi, Elisabeth A. Pitt, Petra de Kruijf, Martine J. Smit, and Tim E. Sparer. "Novel Human Cytomegalovirus Viral Chemokines, vCXCL-1s, Display Functional Selectivity for Neutrophil Signaling and Function." Journal of Immunology 195, no. 1 (May 18, 2015): 227–36. http://dx.doi.org/10.4049/jimmunol.1400291.

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Siddiqui, Zeba Rahman, Rajesh Jhingran, Vivek Kumar Bains, Ruchi Srivastava, Rohit Madan, and Iram Rizvi. "Comparative evaluation of platelet-rich fibrin versus beta-tri-calcium phosphate in the treatment of Grade II mandibular furcation defects using cone-beam computed tomography." European Journal of Dentistry 10, no. 04 (October 2016): 496–506. http://dx.doi.org/10.4103/1305-7456.195160.

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ABSTRACT Objective: The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus β-tri-calcium phosphate (β-TCP) in the treatment of Grade II mandibular furcation defects. Materials and Methods: Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (n = 15), to OFD with β-TCP Group II (n = 15), and to OFD alone Group III (n = 15) were analyzed for clinical parameters (probing pocket depth [PPD], vertical clinical attachment level [VCAL], horizontal clinical attachment level [HCAL], gingival recession, relative vertical height of furcation [r-VHF], and relative horizontal depth of furcation [r-HDF]) and radiographical parameters (horizontal depth of furcation [H-DOF], vertical height of furcation [V-HOF]) using cone-beam computed tomography (CBCT) at 6 months interval. Results: For clinical parameters, reduction in PPD and gain in VCAL and HCAL were higher in Group II as compared to Group I. Change in r-VHF and r-HDF was greater in Group II as compared to Group I. Mean percentage clinical vertical defect fill was higher in Group II as compared to Group I (58.52% ± 11.68% vs. 53.24% ± 13.22%, respectively). On CBCT, mean change at 6 months for all parameters showed nonsignificant difference between the two experimental groups. Mean change in V-HOF was higher in Group I as compared to Group II, but mean change in H-DOF and furcation width was more in Group II as compared to Group I. Conclusion: For both experimental and control groups, there was statistically significant improvement at 6 months follow-up from baseline values.

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Zaghouani Chakroun, Amal, and Dorra Mezzez Hmaied. "Evidence on aggregate volatility risk premium for the French stock market." Managerial Finance 46, no. 1 (October 31, 2019): 72–91. http://dx.doi.org/10.1108/mf-11-2018-0535.

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Purpose The purpose of this paper is to examine alternative six- and seven-factor equity pricing models directed at capturing a new factor, aggregate volatility, in addition to market, size, book to market, profitability, investment premiums of the Fama and French (2015) and Fama and French’s (2018) aggregate volatility augmented model. Design/methodology/approach The models are tested using a time series regression and Fama and Macbeth’s (1973) methodology. Findings The authors show that both six- and seven-factor models best explain average excess returns on the French stock market. In fact, the authors outperform Fama and French’s (2018) model. The authors use sensitivity of aggregate volatility of a stock VCAC as a proxy to construct the aggregate volatility risk factor. The spanning tests suggest that Fama and French’s (1993, 2015, 2018) and Carhart’s (1997) models do not explain the aggregate volatility risk factor FVCAC. The results show that the FVCAC factor earns significant αs across the different multifactor models and even after controlling for the exposure to all the other in Fama and French’s (2018) model. The asset pricing tests show that it is systematically priced. In fact, the authors find a significant and negative (positive) relation between the aggregate volatility risk factor and the excess returns in the French stock market when it is rising (falling), in addition, periods with downward market movements tend to coincide with high volatility. Originality/value The authors contribute to the related literature in several ways. First, the authors test two new empirical six- and seven-factor model and the authors compare them to Fama and French’s (2018) model. Second, the authors give new evidence about the VCAC, using it for the first time to the authors’ knowledge, to construct a volatility risk premium.

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Islam, Shakira S., and Kochi Ismail. "Mixed alkali effect in sodium thiosulfate pentahydrate melt." Canadian Journal of Chemistry 66, no. 2 (February 1, 1988): 242–45. http://dx.doi.org/10.1139/v88-040.

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Density and electrical conductance measurements of 0.35[XNaNO3 + (1 − X)KNO3] + 0.65Na2S2O3•5H2O melt were made as functions of temperature and X. Molar volume, V, is found to be additive. The percent deviation of Vext (extrapolated V of the pure solute from the plot of V vs. total added alkali ion fraction) from Vcal (calculated V of the pure solute from its high temperature density data) increases monotonically as the amount of NaNO3 in the hydrate melt increases, thereby manifesting a "structure-forming" tendency of NaNO3. The non-Arrhenius temperature dependence of molar conductance, Λ is analyzed in terms of the Vogel–Tammann–Fulcher (VTF) equation. Mixed alkali effect (MAE) has been observed on Λ and T0 (ideal glass transition temperature). A competitive polarization model has been used to explain the MAE on Λ.

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Lutz, Thomas, Kiersten Flodman, Alyssa Copelas, Honorata Czapinska, Megumu Mabuchi, Alexey Fomenkov, Xinyi He, Matthias Bochtler, and Shuang-yong Xu. "A protein architecture guided screen for modification dependent restriction endonucleases." Nucleic Acids Research 47, no. 18 (September 3, 2019): 9761–76. http://dx.doi.org/10.1093/nar/gkz755.

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Abstract Modification dependent restriction endonucleases (MDREs) often have separate catalytic and modification dependent domains. We systematically looked for previously uncharacterized fusion proteins featuring a PUA or DUF3427 domain and HNH or PD-(D/E)XK catalytic domain. The enzymes were clustered by similarity of their putative modification sensing domains into several groups. The TspA15I (VcaM4I, CmeDI), ScoA3IV (MsiJI, VcaCI) and YenY4I groups, all featuring a PUA superfamily domain, preferentially cleaved DNA containing 5-methylcytosine or 5-hydroxymethylcytosine. ScoA3V, also featuring a PUA superfamily domain, but of a different clade, exhibited 6-methyladenine stimulated nicking activity. With few exceptions, ORFs for PUA-superfamily domain containing endonucleases were not close to DNA methyltransferase ORFs, strongly supporting modification dependent activity of the endonucleases. DUF3427 domain containing fusion proteins had very little or no endonuclease activity, despite the presence of a putative PD-(D/E)XK catalytic domain. However, their expression potently restricted phage T4gt in Escherichia coli cells. In contrast to the ORFs for PUA domain containing endonucleases, the ORFs for DUF3427 fusion proteins were frequently found in defense islands, often also featuring DNA methyltransferases.

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Sparer, Tim E., Jennifa Gosling, Thomas J. Schall, and Edward S. Mocarski. "Expression of Human CXCR2 in Murine Neutrophils as a Model for Assessing Cytomegalovirus Chemokine vCXCL-1 Function In Vivo." Journal of Interferon & Cytokine Research 24, no. 10 (October 2004): 611–20. http://dx.doi.org/10.1089/jir.2004.24.611.

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이상원. "A Study on the Relationship among the International Investment Sentiment Indicators: VKOSPI, VIX, VDAX-New, and VCAC." Korean Journal of Financial Engineering 9, no. 3 (September 2010): 19–37. http://dx.doi.org/10.35527/kfedoi.2010.9.3.002.

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Sparer, Tim E., Jennifa Gosling, Thomas J. Schall, and Edward S. Mocarski. "Expression of Human CXCR2 in Murine Neutrophils as a Model for Assessing Cytomegalovirus Chemokine vCXCL-1 Function In Vivo." Journal of Interferon & Cytokine Research 24, no. 10 (October 1, 2004): 611–20. http://dx.doi.org/10.1089/1079990042280883.

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Broadbent, Robyn, and Theo Papadopoulos. "What alternative? A snapshot of VCAL as an alternative to senior secondary education in the western region of Melbourne." Research in Post-Compulsory Education 18, no. 3 (September 2013): 209–20. http://dx.doi.org/10.1080/13596748.2013.819255.

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Gittenberger-de Groot, Adriana C., Cornelia Tennstedt, Rabih Chaoui, Heleen Lie-Venema, Ursula Sauer, and Robert E. Poelmann. "Ventriculo coronary arterial communications (VCAC) and myocardial sinusoids in hearts with pulmonary atresia with intact ventricular septum: two different diseases." Progress in Pediatric Cardiology 13, no. 3 (October 2001): 157–64. http://dx.doi.org/10.1016/s1058-9813(01)00102-3.

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Kashif, Muhammad, Muhammad Sultan, and Zahid Mahmood Khan. "Alternative Air-Conditioning Options for Developing Countries." European Journal of Engineering Research and Science 2, no. 1 (January 31, 2017): 76. http://dx.doi.org/10.24018/ejers.2017.2.1.261.

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This study assesses the potential selection of efficient air-conditioning (AC) and cooling systems in order to avoid excess power consumption, mitigation of harmful refrigerants generated by the existing AC systems. Several varieties of active and passive air-conditioning systems i.e. heating ventilating air-conditioning (HVAC), vapor compression air-conditioning (VCAC) conventional direct evaporative cooling (DEC) and indirect evaporative cooling (IEC) and desiccant air-conditioning (DAC) systems are under practice for the cooling and dehumidification. The storage of agricultural products mainly based on product individual characteristics i.e. respiration rate, transpiration rate and moisture content of that product. Variant ambient air conditions and the type of application are the main parameters for the choice of air-conditioning system to get optimum performance. The DAC system subsidize the coefficient of performance (COP) in humid regions, coastal ranges of developing countries e.g. Karachi and Gawadar (Pakistan) with hot humid climatic conditions. In similar way, hottest regions of the country such as Sibbi, Jacobabad and Multan perform better results when incorporates with M-cycle evaporative cooling system. Variation in ambient air conditions directly affect the cooling load and the choice of sustainable air-conditioning system

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Kashif, Muhammad, Muhammad Sultan, and Zahid Mahmood Khan. "Alternative Air-Conditioning Options for Developing Countries." European Journal of Engineering and Technology Research 2, no. 1 (January 31, 2017): 76–79. http://dx.doi.org/10.24018/ejeng.2017.2.1.261.

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This study assesses the potential selection of efficient air-conditioning (AC) and cooling systems in order to avoid excess power consumption, mitigation of harmful refrigerants generated by the existing AC systems. Several varieties of active and passive air-conditioning systems i.e. heating ventilating air-conditioning (HVAC), vapor compression air-conditioning (VCAC) conventional direct evaporative cooling (DEC) and indirect evaporative cooling (IEC) and desiccant air-conditioning (DAC) systems are under practice for the cooling and dehumidification. The storage of agricultural products mainly based on product individual characteristics i.e. respiration rate, transpiration rate and moisture content of that product. Variant ambient air conditions and the type of application are the main parameters for the choice of air-conditioning system to get optimum performance. The DAC system subsidize the coefficient of performance (COP) in humid regions, coastal ranges of developing countries e.g. Karachi and Gawadar (Pakistan) with hot humid climatic conditions. In similar way, hottest regions of the country such as Sibbi, Jacobabad and Multan perform better results when incorporates with M-cycle evaporative cooling system. Variation in ambient air conditions directly affect the cooling load and the choice of sustainable air-conditioning system

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Chatterjee, Shramana, Seema Nath, and Udayaditya Sen. "High resolution structure of Vibrio cholerae acylphosphatase (VcAcP) cage: Identification of drugs, location of its binding site and engineering to facilitate cage formation." Biochemical and Biophysical Research Communications 523, no. 2 (March 2020): 348–53. http://dx.doi.org/10.1016/j.bbrc.2019.12.060.

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Gaber, Dalia Shawky, Nevine Hassan Kheir El Din, Hamdy Ahmed Nassar, Mostafa Saad El-Din Ashmawy, and Ola Mohamed Ezzatt. "Clinical and Biochemical Assessment of Lycopene Gel Combined With Nanohydroxyapatite Graft in Treatment of Grade II Furcation Defects: A Randomized Controlled Clinical Study." Perio J 5, no. 1 (December 31, 2021): 28–37. http://dx.doi.org/10.26810/perioj.2021.a4.

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Background: This study aimed to evaluate the effects of lycopene gel, as a natural antioxidant, mixed with a nanohydroxyapatite graft (NHG) covered by an occlusive resorbable collagen membrane (CM) in the surgical treatment of grade II furcation defects and on the gingival crevicular fluid (GCF) levels of 8-hydroxydeoxyguanosine (8-OHdG), as a marker of oxidative injury. Methods: In this randomized controlled clinical study a total of 24 patients with grade II furcation defects were randomly assigned into three equal groups. Furcation defects in group I were managed with lycopene gel mixed with NHG and CM, group II with NHG and CM, and group III with open flap debridement only. Site-specific changes in clinical parameters including probing depth (PD), vertical clinical attachment level (VCAL), horizontal clinical attachment level (HCAL), radiographic maximum vertical depth (MAX V), and maximum horizontal depth (MAX H) were measured at baseline and six months postoperatively. Gingival crevicular fluid levels of 8-OHdG were analyzed using enzyme-linked immunosorbent assay (ELISA) at baseline, one week, and three months. Results: Surgical management of grade II furcation defects resulted in a significant reduction in PD and 8-OHdG levels and a gain in CAL, MAX V, and MAX H in all groups. The differences between lycopene treated sites compared to NHG and CM alone were not significant at six months but demonstrated significantly superior clinical parameters compared to open flap debridement alone. Conclusion: Lycopene does not confer a benefit when combined with NHG in the surgical treatment of grade II furcation defects.

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Bowden, Mark P., Subhash Abhayawansa, and John Bahtsevanoglou. "Overconfidence of vocational education students when entering higher education." Education + Training 57, no. 4 (May 11, 2015): 429–47. http://dx.doi.org/10.1108/et-02-2014-0012.

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Purpose – There is evidence that students who attend Technical and Further Education (TAFE) prior to entering higher education underperform in their first year of study. The purpose of this paper is to examine the role of self-efficacy in understanding the performance of students who completed TAFE in the previous year in a first year subject of microeconomics in a dual sector university in Melbourne, Australia. Design/methodology/approach – The study utilises data collected by surveys of 151 students. Findings – A student’s self-efficacy is positively associated with their marks in a first year subject of microeconomics. However, the relationship between final marks and self-efficacy is negative for those students who attended TAFE in the previous year suggesting that they suffer from the problem of overconfidence. When holding self-efficacy constant, using econometric techniques, TAFE attendance is found to be positively related to final marks. Research limitations/implications – The findings are exploratory (based on a small sample) and lead to a need to conduct cross institutional studies. Practical implications – The research points to the need for early interventions so that TAFE students perform well in their first year of higher education. It also points to potential issues in the development of Victorian Certificate of Applied Learning (VCAL) programs. Originality/value – To the best of the authors’ knowledge, this is the first paper to examine the inter-related impact of attendance at TAFE in the previous year and self-efficacy on the subsequent academic performance of TAFE students.

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Panda, Sourav, Lorena Karanxha, Funda Goker, Anurag Satpathy, Silvio Taschieri, Luca Francetti, Abhaya Chandra Das, Manoj Kumar, Sital Panda, and Massimo Del Fabbro. "Autologous Platelet Concentrates in Treatment of Furcation Defects—A Systematic Review and Meta-Analysis." International Journal of Molecular Sciences 20, no. 6 (March 17, 2019): 1347. http://dx.doi.org/10.3390/ijms20061347.

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Background: The aim of this review was to evaluate the adjunctive effect of autologous platelet concentrates (APCs) for the treatment of furcation defects, in terms of scientific quality of the clinical trials and regeneration parameters assessment. Methods: A systematic search was carried out in the electronic databases MEDLINE, SCOPUS, CENTRAL (Cochrane Central Register of Controlled Trials), and EMBASE, together with hand searching of relevant journals. Two independent reviewers screened the articles yielded in the initial search and retrieved the full-text version of potentially eligible studies. Relevant data and outcomes were extracted from the included studies. Risk of bias assessment was also carried out. The outcome variables, relative to baseline and post-operative defect characteristics (probing pocket depth (PPD), horizontal and vertical clinical attachment loss (HCAL, VCAL), horizontal and vertical furcation depth (HFD, VFD) were considered for meta-analysis. Results: Ten randomized trials were included in this review. Only one study was judged at high risk of bias, while seven had a low risk, testifying to the good level of the evidence of this review. The meta-analysis showed a favorable effect regarding all outcome variables, for APCs used in adjunct to open flap debridement (p < 0.001). Regarding APCs in adjunct to bone grafting, a significant advantage was found only for HCAL (p < 0.001, mean difference 0.74, 95% CI 0.54, 0.94). The sub-group analysis showed that both platelet-rich fibrin and platelet-rich plasma in adjunct with open flap debridement, yielded significantly favorable results. No meta-analysis was performed for APCs in combination with guided tissue regeneration (GTR) as only one study was found. Conclusion: For the treatment of furcation defects APCs may be beneficial as an adjunct to open flap debridement alone and bone grafting, while limited evidence of an effect of APCs when used in combination with GTR was found.

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Agarwal, Ashish, R. G. Shiva Manjunath, Priyamwada Sethi, and G. Shiva Shankar. "Platelet-rich fibrin in combination with decalcified freeze-dried bone allograft for the management of mandibular degree II furcation defect: A randomised controlled clinical trial." Singapore Dental Journal 39, no. 01 (December 2019): 33–40. http://dx.doi.org/10.1142/s2214607519500032.

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Background: Treatment of furcation involvement of molars with periodontal disease remains challenging and unpredictable. Platelet-rich fibrin (PRF) has received the attention of researchers due to its pleiotropic properties essential for periodontal wound healing. The osteoinductive property of demineralized freeze-dried bone allograft (DFDBA) has been successfully used in periodontal regeneration. Aim: The present study aimed to explore the effectiveness of PRF alone and with DFDBA in the treatment of mandibular degree II furcation defects in subjects with chronic periodontitis. Material and Methods: Patients treated were from the Department of Periodontology and Implantology, Institute of Dental Sciences, Bareilly. A total of 60 mandibular molars were treated with either open flap debridement (OFD) alone, [Formula: see text] combination or [Formula: see text] combination. The soft and hard tissue parameters such as vertical probing depth (VPD), vertical clinical attachment level (VCAL), gingival marginal level (GML), horizontal probing depth (HPD), vertical bone fill (VBF), horizontal bone fill (HBF) and furcation width (FW) were determined at baseline and 9 months postoperatively. A paired [Formula: see text]-test was conducted to assess the statistical significance between time period within each group for clinical and radiographic parameters. ANOVA and post-hoc Tukey’s tests were also conducted for intergroup comparison of soft and hard tissue parameters. Statistical significance was set at [Formula: see text]. Results and Discussion: After 9 months, all treatment groups showed significant ([Formula: see text]) improvement in soft and hard tissue parameters, except GML in all the three groups and HBF and FW in the OFD group as compared to baseline. The mean VBF change was highest in the [Formula: see text] group ([Formula: see text]) mm, followed by that in the [Formula: see text] and OFD groups ([Formula: see text] and [Formula: see text][Formula: see text]mm, respectively). Conclusions: It was shown that both [Formula: see text] and [Formula: see text] combinations were significantly advantageous for the management of mandibular degree II furcation defects. However, the [Formula: see text] combination has significantly greater benefits than [Formula: see text] combination in terms of VBF.

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Jiang, Bo, Xiangjun Fang, Daqi Fu, Weijie Wu, Yanchao Han, Hangjun Chen, Ruiling Liu, and Haiyan Gao. "Exogenous salicylic acid regulates organic acids metabolism in postharvest blueberry fruit." Frontiers in Plant Science 13 (October 17, 2022). http://dx.doi.org/10.3389/fpls.2022.1024909.

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Fruit acidity is an essential factor affecting blueberry organoleptic quality. The organic acid content in blueberry fruit mainly contributes to fruit acidity. This study aims to evaluate the effect of exogenous salicylic acid (SA), the principal metabolite of aspirin, on the organoleptic quality and organic acid metabolism in rabbiteye blueberry (Vaccinium virgatum Ait, ‘Powderblue’) during cold storage (4 °C). Results showed that SA-treated fruit reduced fruit decay and weight loss delayed fruit softening, and decline of total soluble solids (TSS). TA and total organic acid amounts stayed the same during the late storage period in SA-treated fruit. Four kinds of organic acid components, malic acid, quinic acid, citric acid, and succinic acid, were at higher levels in fruit treated by SA as compared to control. SA enhanced the activities of PEPC, NAD-MDH, and CS to promote the synthesis of malic acid and citric acid. Meanwhile, the activities of NADP-ME, ACL, and ACO, which participated in the degradation of malic acid and citric acid, were inhibited by SA. qPCR results also showed that the expression of VcPEPC, VcNAD-MDH, and VcCS genes were upregulated. In contrast, SA downregulated the expression of VcNADP-ME, VcACL, and VcACO genes. In conclusion, SA could regulate the key genes and enzymes that participated in organic acids metabolism to maintain the freshness of blueberry during cold storage, therefore minimizing the economic loss.

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Jackson, Joseph W., Trevor J. Hancock, Ellen LaPrade, Pranay Dogra, Eric R. Gann, Thomas J. Masi, Ravichandran Panchanathan, William E. Miller, Steven W. Wilhelm, and Tim E. Sparer. "The Human Cytomegalovirus Chemokine vCXCL-1 Modulates Normal Dissemination Kinetics of Murine CytomegalovirusIn Vivo." mBio 10, no. 3 (June 25, 2019). http://dx.doi.org/10.1128/mbio.01289-19.

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ABSTRACTHuman cytomegalovirus (HCMV) is a betaherpesvirus that is a significant pathogen within newborn and immunocompromised populations. Morbidity associated with HCMV infection is the consequence of viral dissemination. HCMV has evolved to manipulate the host immune system to enhance viral dissemination and ensure long-term survival within the host. The immunomodulatory protein vCXCL-1, a viral chemokine functioning primarily through the CXCR2 chemokine receptor, is hypothesized to attract CXCR2+neutrophils to infection sites, aiding viral dissemination. Neutrophils harbor HCMVin vivo; however, the interaction between vCXCL-1 and the neutrophil has not been evaluatedin vivo. Using the mouse model and mouse cytomegalovirus (MCMV) infection, we show that murine neutrophils harbor and transfer infectious MCMV and that virus replication initiates within this cell type. Utilizing recombinant MCMVs expressing vCXCL-1 from the HCMV strain (Toledo), we demonstrated that vCXCL-1 significantly enhances MCMV dissemination kinetics. Through cellular depletion experiments, we observe that neutrophils impact dissemination but that overall dissemination is largely neutrophil independent. This work adds neutrophils to the list of innate cells (i.e., dendritic and macrophages/monocytes) that contribute to MCMV dissemination but refutes the hypothesis that neutrophils are the primary cell responding to vCXCL-1.IMPORTANCEAn adequatein vivoanalysis of HCMV’s viral chemokine vCXCL-1 has been lacking. Here we generate recombinant MCMVs expressing vCXCL-1 to study vCXCL-1 functionin vivousing MCMV as a surrogate. We demonstrate that vCXCL-1 increases MCMV dissemination kinetics for both primary and secondary dissemination. Additionally, we provide evidence, that the murine neutrophil is largely a bystander in the mouse’s response to vCXCL-1. We confirm the hypothesis that vCXCL-1 is a HCMV virulence factor. Infection of severely immunocompromised mice with MCMVs expressing vCXCL-1 was lethal in more than 50% of infected animals, while all animals infected with parental virus survived during a 12-day period. This work provides needed insights into vCXCL-1 functionin vivo.

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Chow, Emma, and Pol Dominic Miles-McCann. "Investigating What Victorian Certificate of Applied Learning Students Seek in a Counselling Service." Psychotherapy and Counselling Journal of Australia 7, no. 1 (September 1, 2019). http://dx.doi.org/10.59158/001c.71116.

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Adolescents enrolled in community Victorian Certificate of Applied Learning (VCAL) programs frequently experience a wide range of serious life issues that can disrupt their educational experience, and these students may benefit from the application of counselling. The current study examines how organisations providing the VCAL can implement effective counselling services that will be utilised by students. At present, no existing studies examine what factors would encourage VCAL students to utilise a mental health service provided by their educational program. Data was collected through a web-based qualitative survey. Thematic analysis was applied to the survey responses, and the themes that emerged included interpersonal stress, desire for mutual respect in counselling, and that youth prefer to be autonomous. Participants expressed wanting counselling services which are accessible, flexible, support their own problem solving, and encourage a warm, respectful therapeutic relationship.

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Wang, Zhanyi, Jingli Gong, Jian-Jun He, Lu Li, Rui Q. Yang, and James A. Gupta. "Widely tunable single-mode interband cascade lasers based on V-coupled cavities and dependence on design parameters." Journal of Vacuum Science & Technology B 42, no. 2 (February 8, 2024). http://dx.doi.org/10.1116/6.0003376.

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We report an investigation of V-coupled cavity interband cascade (IC) lasers (ICLs) emitting in the 3-μm wavelength range, employing various waveguide structures and coupler sizes. Type-II ICL devices with double-ridge waveguides exhibited wide tuning ranges exceeding 153 nm. Type-I ICL devices with deep-etched waveguides achieved single-mode emission with wavelength tunable over 100 nm at relatively high temperatures up to 250 K. All devices exhibited a side-mode suppression ratio higher than 30 dB. By comparing the performance of all devices with different sizes and configurations, a good tolerance against the structural parameter variations of the V-coupled cavity laser (VCCL) design is demonstrated, validating the advantages of the VCCL to achieve single-mode emission with wide tunability.

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Wolter, Aline, Natalia Markert, Jan Sebastian Wolter, Andrii Kurkevych, Jan Degenhardt, Jochen Ritgen, Rüdiger Stressig, et al. "Natural history of pulmonary atresia with intact ventricular septum (PAIVS) and critical pulmonary stenosis (CPS) and prediction of outcome." Archives of Gynecology and Obstetrics, February 14, 2021. http://dx.doi.org/10.1007/s00404-020-05929-0.

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Abstract Objectives To analyse prenatal parameters predicting biventricular (BV) outcome in pulmonary atresia with intact ventricular septum/critical pulmonary stenosis (PAIVS/CPS). Methods We evaluated 82 foetuses from 01/08 to 10/18 in 3 centres in intervals 1 (< 24 weeks), 2 (24–30 weeks) and 3 (> 30 weeks). Results 61/82 (74.4%) were livebirths, 5 (8.2%) lost for follow-up, 3 (4.9%) had compassionate care leaving 53 (64.6% of the whole cohort and 86.9% of livebirths) with intention to treat. 9 died, 44/53 (83.0%) survived. 24/38 (63.2%) with information on postnatal outcome had BV outcome, 14 (36.8%) non-BV outcome (2 × 1.5 circulation). One with BV outcome had prenatal valvuloplasty. Best single parameter for BV outcome was tricuspid/mitral valve (TV/MV) ratio (AUC 0.93) in intervals 2 and 3 (AUC 0.92). Ventriculo-coronary-arterial communications (VCAC) were present in 11 (78.6%) in non-BV outcome group vs. 2 (8.3%) in BV outcome group (p < 0.001). Tricuspid insufficiency (TI)-Vmax > 2.5 m/s was present in BV outcome group in75.0% (18/24) vs. 14.3% (2/14) in non-BV outcome group. Including the most predictive markers (VCAC presence, TI- Vmax < 2.5 m/s, TV/MV ratio < cutoff) to a score, non-BV outcome was correctly predicted when > 1 criterion was fulfilled in all cases. After recently published criteria for foetal intervention, only 4/9 (44.4%) and 5/14 (35.7%) in our interval 2 + 3 with predicted non-BV outcome would have been candidates for intervention. Two (1 × intrauterine intervention) in interval 2, two in interval 3 reached BV outcome and one 1.5 circulation without intervention. Conclusion TV/MV ratio as simple parameter has high predictive value. After our score, non-BV outcome was correctly predicted in all cases. Criteria for foetal intervention must further be evaluated.

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Khetan, Vedika. "Volatility Study of French CAC 40 VIX (VCAC) – A Review of GARCH and Information Entropy." SSRN Electronic Journal, 2020. http://dx.doi.org/10.2139/ssrn.3622182.

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Journal articles on the topic 'Vcacl'

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