Relevant bibliographies by topics / Vaccine effectiveness

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Vaccine effectiveness'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Vaccine effectiveness.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Vaccine effectiveness"

1

Pálinkás, Anita, and János Sándor. "Effectiveness of COVID-19 Vaccination in Preventing All-Cause Mortality among Adults during the Third Wave of the Epidemic in Hungary: Nationwide Retrospective Cohort Study." Vaccines 10, no. 7 (June 24, 2022): 1009. http://dx.doi.org/10.3390/vaccines10071009.

Full text
Abstract:
Our investigation aimed to describe the all-cause mortality rates by COVID-19 vaccination groups in Hungary for an epidemic period (1 April 2021–20 June 2021) and a nonepidemic period (21 June 2021–15 August 2021), and to determine the vaccines’ effectiveness in preventing all-cause mortality utilizing nonepidemic effectiveness measures to adjust for the healthy vaccinee effect (HVE). Sociodemographic status, comorbidity, primary care structural characteristics, and HVE-adjusted survival difference between fully vaccinated and unvaccinated cohorts in the epidemic period had been computed by Cox regression models, separately for each vaccine (six vaccines were available in Hungary). Hazard ratio (HR) reduction in epidemic period corrected with nonepidemic period’s HR with 95% confidence interval for each vaccine was used to describe the vaccine effectiveness (VE). The whole adult population (N = 6,404,702) of the country was followed in this study (4,026,849 fully vaccinated). Each vaccine could reduce the HVE-corrected all-cause mortality in the epidemic period (VEOxford/AstraZeneca = 0.592 [0.518–0.655], VEJanssen = 0.754 [0.628–0.838], VEModerna = 0.573 [0.526–0.615], VEPfizer-BioNTech = 0.487 [0.461–0.513], VESinopharm = 0.530 [0.496–0.561], and VESputnik V = 0.557 [0.493–0.614]). The HVE-corrected general mortality for COVID-19 vaccine cohorts demonstrated the real-life effectiveness of vaccines applied in Hungary, and the usefulness of this indicator to convince vaccine hesitants.
APA, Harvard, Vancouver, ISO, and other styles
2

Fly, Mary. "Vaccine Effectiveness." Brain & Life 17, no. 2 (April 2021): 8. http://dx.doi.org/10.1097/01.nnn.0000742788.44428.40.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Trombetta, Claudia Maria, Otfried Kistner, Emanuele Montomoli, Simonetta Viviani, and Serena Marchi. "Influenza Viruses and Vaccines: The Role of Vaccine Effectiveness Studies for Evaluation of the Benefits of Influenza Vaccines." Vaccines 10, no. 5 (May 1, 2022): 714. http://dx.doi.org/10.3390/vaccines10050714.

Full text
Abstract:
Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups. To date, three types of influenza vaccines have been licensed: inactivated, live-attenuated, and recombinant haemagglutinin vaccines. Effectiveness studies allow an assessment of the positive effects of influenza vaccines in the field. The effectiveness of current influenza is suboptimal, being estimated as 40% to 60% when the vaccines strains are antigenically well-matched with the circulating viruses. This review focuses on influenza viruses and vaccines and the role of vaccine effectiveness studies for evaluating the benefits of influenza vaccines. Overall, influenza vaccines are effective against morbidity and mortality in all age and risk groups, especially in young children and older adults. However, the effectiveness is dependent on several factors such as the age of vaccinees, the match between the strain included in the vaccine composition and the circulating virus, egg-adaptations occurring during the production process, and the subject’s history of previous vaccination.
APA, Harvard, Vancouver, ISO, and other styles
4

Helena De Oliveira, Lucia, Barbara Jauregui, Ana Flavia Carvalho, and Norberto Giglio. "Impact and effectiveness of meningococcal vaccines: a review." Revista Panamericana de Salud Pública 41 (December 20, 2017): 1. http://dx.doi.org/10.26633/rpsp.2017.158.

Full text
Abstract:
Objectives.To summarize and critically evaluate the evidence on the impact and effectiveness of meningococcal vaccination programs around the world in order to inform decisionmaking in Latin America and the Caribbean.Methods.A review of the literature was conducted following several components of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed Central® was searched for papers published in any language from January 1999 – March 2017.Results.In all, 32 studies were included, most of which evaluated the meningococcal C conjugate vaccine. Fourteen studies measured effectiveness and 30 measured impact. The effectiveness of polysaccharide vaccines was 65% – 83.7% (different age groups), while the effectiveness of the conjugate vaccines was 66% – 100%. Incidence decline of laboratory-confirmed meningococcal disease for the conjugate vaccine ranged from 77% – 100% among different ages groups. The only study that evaluated the protein subunit vaccine reported a vaccine effectiveness of 82.9%.Conclusions.The studies reviewed show impact and effectiveness of both polysaccharide vaccines and conjugate vaccines on vaccine-serogroup meningococcal disease. The conjugate vaccines, however, show higher impact and effectiveness with longer-lasting protection over the polysaccharide vaccines. Given the variance in potential use of a meningococcal vaccine, epidemiological surveillance systems should be strengthened to inform national decisions.
APA, Harvard, Vancouver, ISO, and other styles
5

Lau, Chin Shern, and Tar Choon Aw. "Considerations in Understanding Vaccine Effectiveness." Vaccines 11, no. 1 (December 22, 2022): 20. http://dx.doi.org/10.3390/vaccines11010020.

Full text
Abstract:
Although vaccine effectiveness reports are essential to assessing policies on SARS-CoV-2 vaccination, several factors can affect our interpretation of the results. These include the waning of antibodies, the prevailing viral variants at the time of the study, and COVID-19 disease prevalence in the population. Disease prevalence significantly impacts absolute risk reduction and could skew expected efficacy when increased disease prevalence inflates the absolute risk reduction in the face of a constant relative risk reduction. These factors must be considered in the interpretation of vaccine effectiveness to better understand how vaccines can improve disease prevention among the population. We highlight the impact of various factors on vaccine effectiveness.
APA, Harvard, Vancouver, ISO, and other styles
6

Stöckli, Sabrina, Anna Katharina Spälti, Joseph Phillips, Florian Stoeckel, Matthew Barnfield, Jack Thompson, Benjamin Lyons, Vittorio Mérola, Paula Szewach, and Jason Reifler. "Which vaccine attributes foster vaccine uptake? A cross-country conjoint experiment." PLOS ONE 17, no. 5 (May 4, 2022): e0266003. http://dx.doi.org/10.1371/journal.pone.0266003.

Full text
Abstract:
Why do people prefer one particular COVID-19 vaccine over another? We conducted a pre-registered conjoint experiment (n = 5,432) in France, Germany, and Sweden in which respondents rated the favorability of and chose between pairs of hypothetical COVID-19 vaccines. Differences in effectiveness and the prevalence of side-effects had the largest effects on vaccine preferences. Factors with smaller effects include country of origin (respondents are less favorable to vaccines of Chinese and Russian origin), and vaccine technology (respondents exhibited a small preference for hypothetical mRNA vaccines). The general public also exhibits sensitivity to additional factors (e.g. how expensive the vaccines are). Our data show that vaccine attributes are more important for vaccine preferences among those with higher vaccine favorability and higher risk tolerance. In our conjoint design, vaccine attributes–including effectiveness and side-effect prevalence–appear to have more muted effects among the most vaccine hesitant respondents. The prevalence of side-effects, effectiveness, country of origin and vaccine technology (e.g., mRNA vaccines) determine vaccine acceptance, but they matter little among the vaccine hesitant. Vaccine hesitant people do not find a vaccine more attractive even if it has the most favorable attributes. While the communication of vaccine attributes is important, it is unlikely to convince those who are most vaccine hesitant to get vaccinated.
APA, Harvard, Vancouver, ISO, and other styles
7

Bansal, Devendra, Jazeel Abdulmajeed, Maha H. M. A. Al-Shamali, Soha S. A. Albayat, Sayed M. Himatt, Farhan S. Cyprian, Tawanda Chivese, et al. "Duration of COVID-19 mRNA Vaccine Effectiveness against Severe Disease." Vaccines 10, no. 7 (June 28, 2022): 1036. http://dx.doi.org/10.3390/vaccines10071036.

Full text
Abstract:
Waning immunity following administration of mRNA-based COVID-19 vaccines remains a concern for many health systems. We undertook a study to determine if recent reports of waning for severe disease could have been attributed to design-related bias by conducting a study only among those detected with a first SARS-CoV-2 infection. We used a matched case-control study design with the study base being all individuals with first infection with SARS-CoV-2 reported in the State of Qatar between 1 January 2021 and 20 February 2022. Cases were those detected with first SARS-CoV-2 infection requiring intensive care (hard outcome), while controls were those detected with first SARS-CoV-2 infection who recovered without the need for intensive care. Cases and controls were matched in a 1:30 ratio for the calendar month of infection and the comorbidity category. Duration and magnitude of conditional vaccine effectiveness against requiring intensive care and the number needed to vaccinate (NNV) to prevent one more case of COVID-19 requiring intensive care was estimated for the mRNA (BNT162b2/mRNA-1273) vaccines. Conditional vaccine effectiveness against requiring intensive care was 59% (95% confidence interval (CI), 50 to 76) between the first and second dose, and strengthened to 89% (95% CI, 85 to 92) between the second dose and 4 months post the second dose in persons who received a primary course of the vaccine. There was no waning of vaccine effectiveness in the period from 4 to 6, 6 to 9, and 9 to 12 months after the second dose. This study demonstrates that, contrary to mainstream reports using hierarchical measures of effectiveness, conditional vaccine effectiveness against requiring intensive care remains robust till at least 12 months after the second dose of mRNA-based vaccines.
APA, Harvard, Vancouver, ISO, and other styles
8

Kamolratanakul, Supitcha, and Punnee Pitisuttithum. "Human Papillomavirus Vaccine Efficacy and Effectiveness against Cancer." Vaccines 9, no. 12 (November 30, 2021): 1413. http://dx.doi.org/10.3390/vaccines9121413.

Full text
Abstract:
Human papillomavirus (HPV) is the most common sexually transmitted infection, with 15 HPV types related to cervical, anal, oropharyngeal, penile, vulvar, and vaginal cancers. However, cervical cancer remains one of the most common cancers in women, especially in developing countries. Three HPV vaccines have been licensed: bivalent (Cervarix, GSK, Rixensart, Belgium), quadrivalent (Merck, Sharp & Dome (Merck & Co, Whitehouse Station, NJ, USA)), and nonavalent (Merck, Sharp & Dome (Merck & Co, Whitehouse Station, NJ, USA)). The current HPV vaccine recommendations apply to 9 years old and above through the age of 26 years and adults aged 27–45 years who might be at risk of new HPV infection and benefit from vaccination. The primary target population for HPV vaccination recommended by the WHO is girls aged 9–14 years, prior to their becoming sexually active, to undergo a two-dose schedule and girls ≥ 15 years of age, to undergo a three-dose schedule. Safety data for HPV vaccines have indicated that they are safe. The most common adverse side-effect was local symptoms. HPV vaccines are highly immunogenic. The efficacy and effectiveness of vaccines has been remarkably high among young women who were HPV seronegative before vaccination. Vaccine efficacy was lower among women regardless of HPV DNA when vaccinated and among adult women. Comparisons of the efficacy of bivalent, quadrivalent, and nonavalent vaccines against HPV 16/18 showed that they are similar. However, the nonavalent vaccine can provide additional protection against HPV 31/33/45/52/58. In a real-world setting, the notable decrease of HPV 6/11/16/18 among vaccinated women compared with unvaccinated women shows the vaccine to be highly effective. Moreover, the direct effect of the nonavalent vaccine with the cross-protection of bivalent and quadrivalent vaccines results in the reduction of HPV 6/11/16/18/31/33/45/52/58. HPV vaccination has been shown to provide herd protection as well. Two-dose HPV vaccine schedules showed no difference in seroconversion from three-dose schedules. However, the use of a single-dose HPV vaccination schedule remains controversial. For males, the quadrivalent HPV vaccine possibly reduces the incidence of external genital lesions and persistent infection with HPV 6/11/16/18. Evidence regarding the efficacy and risk of HPV vaccination and HIV infection remains limited. HPV vaccination has been shown to be highly effective against oral HPV type 16/18 infection, with a significant percentage of participants developing IgG antibodies in the oral fluid post vaccination. However, the vaccines’ effectiveness in reducing the incidence of and mortality rates from HPV-related head and neck cancers should be observed in the long term. In anal infections and anal intraepithelial neoplasia, the vaccines demonstrate high efficacy. While HPV vaccines are very effective, screening for related cancers, as per guidelines, is still recommended.
APA, Harvard, Vancouver, ISO, and other styles
9

Diogo José Horst and Charles Adriano Duvoisin. "The doubtful effectiveness of the COVID-19 vaccine." GSC Biological and Pharmaceutical Sciences 15, no. 2 (May 30, 2021): 151–57. http://dx.doi.org/10.30574/gscbps.2021.15.2.0132.

Full text
Abstract:
A COVID-19 pandemic has erupted around the world. World Health Organization (WHO) and allies are racing to create and deploy safe and effective vaccines as they work together to monitor the pandemic, advise on crucial measures, and distribute essential medical resources to those in need. Vaccines save millions of lives, by training the body's natural defenses, the immune system, to identify and combat the viruses and bacteria they are intended to combat. This review article presents the status of COVID-19 vaccines evaluated by the WHO Emergency Use Listing (EUL) assessment process and those liberated as well. Data was obtained from the WHO, Gavi – The Vaccine Alliance from Bill & Melinda Gates Foundation, Oxford Vaccine Group, Serum Institute of India, AstraZeneca, European Medicines Agency EMA among others. As can be seen, there is still no totally effective vaccine, and many clinical trials are still needed, and even immunized citizens are still at risk of recontagion. Virus mutation is a recurring problem and different vaccine production methodologies are still being studied.
APA, Harvard, Vancouver, ISO, and other styles
10

Ferdinands, Jill M., Manish M. Patel, Ivo M. Foppa, and Alicia M. Fry. "Influenza Vaccine Effectiveness." Clinical Infectious Diseases 69, no. 1 (December 18, 2018): 190–91. http://dx.doi.org/10.1093/cid/ciy1084.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Vaccine effectiveness"

1

Channing, Liezl. "Cost-effectiveness analysis of MVA85 vaccine: a new TB vaccine candidate." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/9448.

Full text
Abstract:
Includes bibliographical references.
Tuberculosis (TB) remains a major public health concern. The BCG vaccine is, currently, the only vaccine against TB and, although it provides some protection against disseminated forms of TB, its effectiveness in preventing primary infection and disease progression to pulmonary TB is highly varied. A number of potential new TB vaccine candidates have been identified and are, currently, undergoing clinical trials. One such candidate is MVA85A. This study aims to assess the potential cost-effectiveness of a new TB vaccine, the MVA85A vaccine. The study compares two TB vaccine strategies, from the perspective of the South African Government: i. BCG, given at birth, which is the current standard of care in South Africa; and ii BCG, given at birth, together with a booster vaccine (MVA85A) given at 4 months, which is the potential new strategy. The study employs Decision Analytical Modelling, through the use of a Markov model, to estimate the costs and outcomes of the two strategies. The cumulative costs and outcomes of each intervention are used to calculate the cost-effectiveness ratio (CER) (i.e. the cost per TB case averted and the cost per TB death averted) for each intervention. These two cost-effectiveness ratios are compared using an incremental cost-effectiveness ratio (ICER), which represents the additional cost per additional benefit received. The results of the cost-effectiveness analysis indicate that the MVA85A strategy is both more costly and more effective – there are fewer TB cases and deaths from TB – than BCG alone. The Government would need to spend an additional USD 1,105 for every additional TB case averted and USD 284,017 for every additional TB death averted. Given the disappointing results of the MVA85A vaccine clinical trial – showing an efficacy of only 17.3%, this study will predominantly contribute to establishing an efficacy threshold for future vaccines. Our research also contributes to the body of knowledge on economic evaluations involving new TB vaccines as - to the best of our knowledge - this is the first cost-effectiveness analysis conducted using trial data involving a novel TB vaccine and providing a direct comparison with BCG vaccination. Furthermore, it provides a standardized Markov model, which is relatively simple to adapt to local settings and, which could be used in the future, to estimate the potential cost-effectiveness of new TB vaccines in children between the ages of 0–10 years.
APA, Harvard, Vancouver, ISO, and other styles
2

McIntyre, Peter. "Measuring the public health impact of vaccines: disease burden, vaccine coverage, safety and effectiveness." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/26251.

Full text
Abstract:
This thesis has eight chapters describing inter-relationships between work in 66 papers published between 1999 and 2020 relevant to the over-arching topic of public health impact of vaccines: measurement of disease burden, vaccine coverage, safety and effectiveness Chapter 1 outlines the key data sources used: 1. routinely collected administrative data (disease notifications, ICD coded hospitalisations and mortality data) and 2. additional data sources the author had a key role in developing (National Serosurveillance. Paediatric Active Enhanced Surveillance (PAEDS). In chapter 4, development of analysis and reporting of data from the Australian Immunisation Register and in chapter 6 development of platforms for vaccine safety evaluation are described. In Chapter 5, how this work culminated in pilot initiatives to link data sources relevant to public health impact of vaccines in a birth cohort from New South Wales and Western Australia, with the aim of demonstrating the potential for an all-age national capacity, is outlined. Chapter 2 focuses on disease due to Bordetella pertussis and research under the headings of measuring prevalence and severity of pertussis, the effectiveness and impact of pertussis vaccines and clinical trials conducted to evaluate the immunogenicity and safety of acellular pertussis vaccine given within 4 days of birth. Chapter 3 focuses on disease due to Streptococcus pneumoniae and research measuring pneumococcal disease, effectiveness and impact of pneumococcal vaccines and a randomised trial comparing immune responses to pneumococcal conjugate and polysaccharide vaccines in the frail elderly. Chapter 7 includes studies of vaccine impact against Hepatitis B, varicella, meningococcal C disease, mumps and Q fever and Chapter 8 includes four major international reviews of vaccine programs and impact.
APA, Harvard, Vancouver, ISO, and other styles
3

Leung, May-bo Mabel, and 梁美寶. "The cost effectiveness of varicella vaccination program : a systemic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206948.

Full text
Abstract:
Background Chickenpox is a common infectious disease among children. Ever since a live attenuated vaccine was developed in 1970s, different countries have adopted different vaccination program against chickenpox. Hong Kong recently has commenced a routine childhood varicella vaccination program. The objective of this study is to evaluate whether routine childhood varicella vaccination is cost effective and the implications to Hong Kong. Methodology Literature search was done on electronic databases: Medline and Embase for articles relevant to the topic. A total of 9 articles were retrieved for this systemic review. All 9 studies focus on the cost effectiveness of childhood varicella vaccination with comparison to no vaccination or other interventions. Findings Routine childhood varicella vaccination program is cost effective especially from the societal perspective. The longer the vaccination program takes place, the more cost effective it would be. The cost effectiveness ratio is most sensitive to the coverage rate and the vaccine price. Conclusion It remains unclear whether the routine childhood varicella vaccination program in Hong Kong would be cost effective or not. As the Hong Kong program has adopted the most recent recommendations towards varicella vaccines that the review articles were not included.
published_or_final_version
Public Health
Master
Master of Public Health
APA, Harvard, Vancouver, ISO, and other styles
4

Wadanambi, Arachchige Sanjay Harsha Jayasinghe. "Long-term impact and effectiveness of vaccines on invasive pneumococcal disease in Australian children." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20156.

Full text
Abstract:
Pneumococcal disease is a leading cause of morbidity and mortality in children globally. Pneumococcal conjugate vaccines (PCVs), available since early 2000, had proven efficacy to prevent invasive pneumococcal disease (IPD)-the sever form of pneumococcal infections. For Australian children PCV had been publicly funded through the national immunisation program, initially in 2001 for those with increased disease risk which included Aboriginal and Torres Strait Islander children and from 2005 for all children. The schedule of PCV used in Australia comprising three doses at age 2, 4 and 6 months (called 3+0 schedule) was unique for a developed country. The first PCV used was one covering 7 serotypes of pneumococcus (7vPCV) and in 2011 a PCV that covered 6 more serotypes (13vPCV) replaced 7vPCV. Research contained in this thesis is the first to assess how well PCV prevented IPD among Australian children. After 9 years of combined PCV use IPD in young children declined by over 80%. Together with the added benefit of herd immunity that led to large reductions in IPD in older age groups there was a halving of the all-age total IPD burden. Vaccine effectiveness (VE) of 3 doses against vaccine-type IPD in infancy was ~90% for both PCVs. A major finding in this research was the 5 times higher odds of vaccine-type IPD if the last PCV dose was 24–36 months ago compared to within the last 12 months. This finding of waning VE was a vital piece of evidence that supported the recommendation to move the 3rd dose of 13vPCV in the 3+0 schedule to become a booster dose (i.e. 2+1 schedule) for Australian children from July 2018. Using a data linkage method the impact of PCVs on IPD in children with underlying medical conditions predisposing to pneumococcal infection was explored separately. This highlighted the persistent IPD burden in children with immunosuppression, splenic dysfunction and breach in the CSF barrier, possibly due to opportunistic infection from non-vaccine serotypes.
APA, Harvard, Vancouver, ISO, and other styles
5

Wong, Kwan-ting, and 王筠婷. "The cost-effectiveness of 13-valent pneumococcal conjugate vaccine for older adults : a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206978.

Full text
Abstract:
BACKGROUND: Despite the current recommendation by the Centre for Health Protection (CHP)of Hong Kong for adults aged 65 years or above to receive 23-valent pneumococcal polysaccharide vaccine (PPV23), pneumococcal disease(PD) has become the second leading causes of death in Hong Kong. A relatively new pneumococcal vaccine –13-valent pneumococcal conjugate vaccine (PCV13) was approved by the US Food and Drug Administration (FDA) in December 2011 and the European Medicines Agency (EMA) in July 2013 for the prevention of invasive disease caused by S. pneumoniae for older adults aged 50 years or above. It was shown to overcome some of the limitations of PPV23and potentially confer benefits to older adults in the prevention of PD. OBJECTIVES: To systematically review available literatures to examine whether PCV13 is superior to PPV23 or no vaccination in terms of the cost-effectiveness in the prevention of PD in older adults aged 50 years or above. METHODS: Two databases, PubMed and ISI Web of Science, were used to search for published journals. The year range of search in these databases was confined to10 years. RESULTS: A total of 318studies were identified initially and 10studies were included in this systematic review. Studies were conducted in the US, Colombia and European Union (EU) countries e.g. Italy, Germany, Netherlands and Spain. Different perspectives including societal, payer and health system were considered. The use of PCV13 was compared to either PPV23 or no vaccination in older adults aged 50 years or above. The coverage of PCV13 ranged from 42.4% to 70%, conferring an efficacy between 58% and 93.9%. The cost-effectiveness of PCV13 was expressed through the number of avoided cases/deaths for PD including invasive pneumococcal disease(IPD), inpatient and outpatient community-acquired pneumonia (CAP) as well as the incremental cost-effectiveness ratios (ICERs),either in cost per quality-adjusted life-year (QALY) gained or cost per life-year gained (LYG).Overall, PCV13 is shown to avoid more pneumococcal cases compared to PPV23 or no vaccination and is cost-effective in older adults aged 50 years of above. CONCLUSION: PCV13 is considered to be more cost-effective in older adults compared to PPV23 or no vaccination based on the current systematic review. Randomized controlled trials and cost-effectiveness evaluations are suggested to be conducted in Hong Kong and Asia-specific regions in order to obtain clinical and economic data of PCV13 in the Asian population. Policy-makers should also consider the effects of serotype replacement on the change in serotype distribution in local setting from time to time so that vaccines with appropriate serotype formulations could be researched.
published_or_final_version
Public Health
Master
Master of Public Health
APA, Harvard, Vancouver, ISO, and other styles
6

Donauer, Stephanie. "Determining the Post-Licensure Effectiveness of Pentavalent Rotavirus Vaccine using Observational Study Designs." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368026785.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Skull, Susan. "Effectiveness of influenza and pneumococcal vaccination against hospitalisation for community-acquired pneumonia among persons >65 years /." Connect to thesis, 2007. http://repository.unimelb.edu.au/10187/1998.

Full text
Abstract:
Although there are well-documented benefits from influenza vaccine and 23-valent pneumococcal polysaccharide vaccine (23vPPV) against invasive pneumococcal disease and laboratory confirmed influenza, their effectiveness against pneumonia remains controversial for community-based persons aged >=65years. At the time of this research, within Australia, only the government of Victoria publicly funded these vaccines for elderly persons. With continued growth of the elderly population, the subsequent adoption of an Australia-wide program, and increasing uptake of similar programs in other countries, there is a need for data clarifying the impact of vaccination on pneumonia. This research estimates incremental vaccine effectiveness of 23vPPV over and above influenza vaccine against hospitalisation with community-acquired pneumonia (CAP) in the elderly.
APA, Harvard, Vancouver, ISO, and other styles
8

De, La Hoz Fernando. "Hepatitis B vaccination in the Columbian Amazon : effectiveness and factors influencing vaccine coverage." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2003. http://researchonline.lshtm.ac.uk/1544171/.

Full text
Abstract:
A vaccination coverage survey was carried out in the Colombian Amazon, a former high endemic area for hepatitis B, involving 3573 children less than II years old. It was carried out in Leticia, Puerto Narifio, and Araracuara, both urban and rural areas. Children were selected using a one stage cluster sampling, randomly selecting clusters in urban and rural areas where all children under 11 were surveyed. At the same time blood samples were taken from all children with known vaccination status (n=1603), and from their mother, when she was available (n=8l2). These samples were processed for hepatitis B surface antigen (HBsAg), antibodies to hepatitis B core antigen (Anti-HBc) and antibodies to HBsAg (Anti- HBs). A sample of children without vaccination data available was also bled to compare their results with those of children with vaccination data. Full vaccination coverage was found to range between 39% and 69% among different areas while hepatitis B vaccination ranged between 73% and 95%. Factors which improve the likelihood of being fully vaccinated in this study were: Age above one year, living in Leticia, being. affiliated to the social security, mother's years of schooling. Health worker's knowledge on vaccine contraindications and perceptions of logistical barriers against vaccination or importance of hepatitis B as a public health problem were also related to full vaccine coverage. Prevalence of hepatitis B infection reached 5% among those who were bled (8211603) while HBsAg positive status was 1.6% (26/1603). Since the introduction of the vaccine prevalence of hepatitis B infection has fallen from 40%, an 85% reduction, while carrier prevalence has fallen from 5%, a 68% reduction. Age above 7 years, living in a rural area, birth delivery supervised by other than a MD or nurse, and being born from an Anti-HBc+ mother were the most important general factors related to being infected with HBV. Having an incomplete schedule for hepatitis B vaccine was associated with an increase in the risk of being Anti- HBc or HBsAg+. However, some characteristics of the vaccination process were related to being HBsAg+/Anti-HBc+. Delays in receiving the first dose of hepatitis B after birth and delays to receiving the second dose after the first dose were associated with an increased risk of being HBsAg+/Anti-HBc+. None of these characteristics were related to being Anti-Hlic+ alone. In conclusion, the introduction of a recombinant Cuban manufactured hepatitis B vaccine has produced a marked decline in the high infection prevalence of children in the Colombian Amazon area. A higher coverage has been achieved from the beginning of the program though intervals from birth to first dose and between doses are too long leading to new infections that could have been avoided. There is still room to make improvements in the control program, including the implementation of a surveillance system of the HBV serological status for pregnant women, in order to ensure better vaccination schemes for those born to infected or HBsAg+ mothers.
APA, Harvard, Vancouver, ISO, and other styles
9

Bennett, Aisleen May. "Rotavirus transmission in the context of reduced vaccine effectiveness in low income countries." Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3019186/.

Full text
Abstract:
Introduction. Rotavirus vaccine has been introduced into over 80 countries with substantial impact on rotavirus disease. However vaccine effectiveness is reduced in low-income countries. Patterns of rotavirus transmission could explain some of the observed reduced vaccine effectiveness, and vaccine-mediated reductions in rotavirus transmission may increase overall vaccine impact. A detailed understanding of rotavirus transmission in low income countries (LIC) is required to inform policy decisions to improve vaccine performance, however such data are currently lacking. Methods. Mixture models were used as a novel method to estimate population level incidence of rotavirus in young children from serology data and describe transmission patterns in India and Malawi. Surveillance data from Queen Elizabeth Central Hospital, Malawi, were used to describe the ongoing burden of rotavirus disease after vaccine introduction and investigate for vaccine indirect effects. To investigate whether rotavirus vaccine could reduce the infectiousness of a child with rotavirus disease a household transmission study was conducted in Blantyre, Malawi to describe rates of rotavirus transmission from a symptomatic index child to household contacts, investigate predictors of viral shedding density in the index child and identify risk factors for transmission. In a final study transmission of vaccine virus from vaccinated infants to unvaccinated contacts was evaluated to investigate for horizontal transmission of vaccine virus. Results. Mixture models described clear differences in patterns of rotavirus incidence in young children from India and Malawi. Analysis of surveillance data showed that rotavirus remains an important cause of hospitalised diarrhoeal disease in Blantyre despite high vaccine coverage, and identified some evidence of an indirect effect in unvaccinated infants. Household studies found a high rate of transmission of infection to household contacts (434/665, 65%) but a lower rate of transmission for disease (37/698, 5.3%). Disease severity in the index child was associated with an increased risk of transmission to household contacts, independent of viral shedding density. Rates of transmission of vaccine virus to household contacts were very low (2/151, 1.3%). Conclusions. These studies demonstrate that rotavirus remains a significant cause of admitted diarrhoeal disease in Blantyre, Malawi and describe some evidence of a vaccine indirect effect. Transmission rates of rotavirus infection to household contacts are associated with disease severity in the index child. As vaccine provides incremental protection against severe disease, vaccination therefore has potential to reduce the infectiousness of a vaccinated index child. Horizontal transmission of vaccine virus is infrequent and unlikely to make a substantial contribution to rotavirus vaccine indirect effects in this setting. In view of high vaccine coverage future studies should consider mathematical models to make inferences on the impact of vaccine and inform ongoing vaccine strategy.
APA, Harvard, Vancouver, ISO, and other styles
10

Rondy, Marc. "Efficacité post autorisation de mise sur le marché de la vaccination antigrippale saisonnière contre l’hospitalisation avec une grippe confirmée virologiquement chez l’adulte en Europe." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0684/document.

Full text
Abstract:
Notre objectif était de mesurer chez les adultes en Europe l’efficacité des vaccins (EV) anti-grippaux saisonniers contre l’hospitalisation avec une grippe confirmée en laboratoire. Nous avons coordonné une étude cas-témoins multicentrique dans 29 hôpitaux de 12 pays entre 2011 et 2017. Nous avons fait une analyse des données groupées lors de chaque saison grippale. Entre 2011-12 et 2016-17, nous avons recruté 3436 cas de grippe et 5969 témoins. L’EV tous virus confondus était de 26% ; elle était de 40% chez les 18-64 ans, 25% chez les 65-79 ans et 23% chez les 80 ans et plus. Par saison, l’EV variait entre 15% en 2016-17 et 44% en 2013-14. L’EV était particulièrement basse chez les seniors lors des saisons grippales dominées par le sous-type de grippe A(H3N2), atteignant 10% en 2011-12 et 2016-17 chez les personnes âgées de 80 ans et plus. Nos résultats suggèrent une EV faible à modérée contre la grippe hospitalisée chez l’adulte. Le renforcement et l’évaluation de modes de prévention complémentaires, tels que l’usage prophylactique d’antiviraux, la vaccination du personnel soignant et les approches non-pharmaceutiques (masque, hygiène des mains) devraient être une priorité
Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Vaccine effectiveness"

1

Shalala, Donna E. Medicare influenza vaccine demonstration: Report to Congress. [Washington, D.C.?: Dept. of Health and Human Services], 1993.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Sullivan, Louis Wade. Cost-effectiveness demonstration of Medicare coverage of influenza vaccine: Report to Congress. [Washington, D.C.?: Dept. of Health and Human Services], 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Chan, Kwai-Cheung. Medical readiness: Issues concerning the anthrax vaccine : statement of Kwai-Cheung Chan, Director, Special Studies and Evaluations, National Security and International Affairs Division, before the Subcommittee on National Security, Veterans' Affairs, and International Relations, Committee on Government Reform, House of Representatives. Washington, D.C. (P.O. Box 37050, Washington, D.C. 20013): The Office, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Chan, Kwai-Cheung. Medical readiness: Safety and efficacy of the anthrax vaccine : statement of Kwai-Cheung Chan, Director, Special Studies and Evaluations, National Security and International Affairs Division, before the Subcommittee on National Security, Veterans' Affairs, and International Relations, Committee on Government Reform, House of Representatives. Washington, D.C: The Office, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Chan, Kwai-Cheung. Medical readiness: Safety and efficacy of the anthrax vaccine : statement of Kwai-Cheung Chan, Director, Special Studies and Evaluations, National Security and International Affairs Division, before the Subcommittee on National Security, Veterans' Affairs, and International Relations, Committee on Government Reform, House of Representatives. Washington, D.C: The Office, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

R, Berndt Ernst, and National Bureau of Economic Research., eds. Advanced purchase commitments for a malaria vaccine: Estimating costs and effectiveness. Cambridge, MA: National Bureau of Economic Research, 2005.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

R, Berndt Ernst, and National Bureau of Economic Research., eds. Advanced purchase commitments for a malaria vaccine: Estimating costs and effectiveness. Cambridge, Mass: National Bureau of Economic Research, 2005.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Taehak, Sŏul Taehakkyo Ŭikwa, ed. Inpʻŭlluenja paeksin (soa) yuyongsŏng pʻyŏngka yŏnʼgu: Yŏnʼgu kyŏlgwa pogosŏ = Evaluation of efficacy of influenza vaccine in children. [Seoul]: Sikpʻum Ŭiyakpʻum Anjŏnchʻŏng, 2007.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Communicating about Vaccine Safety: Guidelines to help health workers communicate with parents, caregivers, and patients. Pan American Health Organization, 2021. http://dx.doi.org/10.37774/9789275122822.

Full text
Abstract:
Vaccines save between 2 million and 3 million lives each year and protect the entire population from more than a dozen life-threatening diseases. Thanks to vaccination, smallpox was eradicated in 1980, and we are on track to eradicate polio. However, despite great strides in the control of measles, one of the most contagious diseases known, the last few years have unfortunately seen an increase in cases. This is why high vaccination coverage—95% or more—is needed, posing a major technical and communication challenge for health workers. Studies show that telling people about the quality, safety, effectiveness and availability of vaccines is not enough to influence behavior change related to immunization, and in general, doesn´t increase coverage. For this reason, it´s necessary to understand the reasons why people choose not to get vaccinated or not get their children vaccinated, in order to begin a two-way respectful dialogue using the best, most effective messages. Given this context, the main objective of these guidelines is to provide tools for staff working in the field of immunization to support effective communication between health personnel and the general population, with the aim of strengthening, maintaining or recovering trust in vaccines and the immunization programs in the Region of the Americas.
APA, Harvard, Vancouver, ISO, and other styles
10

Казачинская, Е. И. ВИРУС ДЕНГЕ. Академическое изд-во «Гео», 2021. http://dx.doi.org/10.21782/b978-5-6043022-6-2.

Full text
Abstract:
The review is devoted to the analysis of literature data on the history research of dengue fever, the discovery of the etiological infectious agent of this disease-dengue virus and its serotypes. A taxonomic overview of the }lavivirus family, genome organization, structure and function of viral proteins, mosquito species-viral vectors and virus transmission cycles, theories of its origin are presented. As well as the evolution, characteristics and epidemiology of viral serotypes, cellular receptors for dengue virus penetration, pathogenicity for human and factors for the development of severe disease, induced immunity, applied methods and markers for diagnosis, principles of disease treatment and drug development (more information about monoclonal antibodies-potential therapeutic drugs), vaccine options and their effectiveness are considered. The book is intended for students, graduate students, employees of research institutions and universities, as well as doctors involved in the study of }laviviruses and the problem of differential diagnosis of flavivirus infections.
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Vaccine effectiveness"

1

Hahné, Susan, Kaatje Bollaerts, and Paddy Farrington. "Vaccine effectiveness." In Vaccination Programmes, 223–44. London: Routledge, 2021. http://dx.doi.org/10.4324/9781315166414-16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Nauta, Jozef. "Vaccine Effectiveness Studies." In Springer Series in Pharmaceutical Statistics, 129–50. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-37693-2_9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Hahné, Susan, Kaatje Bollaerts, and Paddy Farrington. "Estimating vaccine effectiveness." In Vaccination Programmes, 289–308. London: Routledge, 2021. http://dx.doi.org/10.4324/9781315166414-19.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Hahné, Susan, Kaatje Bollaerts, and Paddy Farrington. "Estimating vaccine effectiveness." In Vaccination Programmes, 245–63. London: Routledge, 2021. http://dx.doi.org/10.4324/9781315166414-17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Hahné, Susan, Kaatje Bollaerts, and Paddy Farrington. "Estimating vaccine effectiveness." In Vaccination Programmes, 264–88. London: Routledge, 2021. http://dx.doi.org/10.4324/9781315166414-18.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Kerns, Thomas A. "Criteria of Effectiveness." In Ethical Issues in HIV Vaccine Trials, 77–93. London: Palgrave Macmillan UK, 1997. http://dx.doi.org/10.1057/9780230380011_10.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Hahné, Susan, Kaatje Bollaerts, and Paddy Farrington. "Waning vaccine effectiveness and modes of vaccine action." In Vaccination Programmes, 309–35. London: Routledge, 2021. http://dx.doi.org/10.4324/9781315166414-20.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Nauta, Jozef. "Meta-Analysis of Vaccine Effectiveness Studies." In Springer Series in Pharmaceutical Statistics, 151–60. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-37693-2_10.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Mueller, Siguna. "The Challenge of Evaluating Vaccine Safety and Effectiveness." In Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2, 131–62. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-18903-6_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Whitney, Cynthia G., and Matthew R. Moore. "Direct and Indirect Effectiveness and Safety of Pneumococcal Conjugate Vaccine in Practice." In Pneumococcal Vaccines, 351–68. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815820.ch24.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Vaccine effectiveness"

1

Zughaier, Susu. "High Vaccine Coverage is Crucial for Preventing the Spread of Infectious Diseases During Mass Gathering." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0138.

Full text
Abstract:
Background: Vaccines are the most cost-effective intervention in public health as they prevent the spread of highly contagious infectious diseases. Because of vaccine implementation and high coverage, Measles was eradicated in 2000, however the recent reappearance of measles in the United States, Europe and globally is alarming. The resurgence of Measles, Diphtheria and Mumps is due to a reduction in vaccine coverage and herd immunity. Vaccine hesitant parents, antivaxxers, and fake news on vaccines are driving the surge in those infectious diseases. The World Health Organization issued the Global Vaccine and Immunization Action Plan to reiterate the importance of vaccine implementation and coverage for several vaccine-preventable infectious diseases in the world. Qatar is preparing for the upcoming FIFA World Cup 2022 therefore maintaining high vaccine coverage, which is critical in preventing infectious diseases spreading during such mass gathering. Methods: Literature search for vaccine coverage rates, resurgence of vaccine preventable infectious diseases and risks of mass gatherings. Results: Seventeen infectious diseases are currently vaccine-preventable. The cost-effectiveness of vaccine is documented as it is estimated for each dollar spent on vaccines, 10 dollars are saved in disease treatment. A drop in vaccine coverage rates to under 90% lead to the resurgence of measles. Vaccine coverage rate in Qatar is currently at 95% which is one of the highest in the world. Qatar must maintain this high coverage rate to prevent any measles outbreaks during mass gatherings. The planned World Cup event will take place from November 21 till December 18 2022, which is the peak for seasonal influenza. In preparedness for this major event, Qatar should encourage residents and visitors to be vaccinated not just against measles and seasonal influenza, but also hepatitis and meningitis. Conclusion: Maintaining 95% vaccine coverage rate is critical for preventing the resurgence of vaccine-preventable infectious diseases during the World Cup mass gathering in Qatar.
APA, Harvard, Vancouver, ISO, and other styles
2

Tarabrin, R. E., and E. S. Pyatigorec. "BIOETHICAL ISSUES OF VACCINOMICS." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-130.

Full text
Abstract:
Vaccinomics, as one of the areas of personalized medicine, can increase the effectiveness of vaccines, including in epidemics. Nevertheless, it is accompanied by a cluster of bioethical issues. The article explores possible bioethical difficulties associated with the development of personalized vaccines: the matching of the research subject and the person receiving the vaccine; the problem of confidential genetic data; equitable distribution of medical resources.
APA, Harvard, Vancouver, ISO, and other styles
3

Capão, Artur, Braulia Caetano, Paola Resende, Milene Miranda, David Brown, Marilda Siqueira, and Cristiana Garcia. "Effectiveness of 2018 trivalent influenza vaccine on healthcare professionals." In IV International Symposium on Immunobiologicals & VII Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2019. http://dx.doi.org/10.35259/isi.sact.2019_32545.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Adami, Giovanni, Angelo Fassio, Giovanni Orsolini, Alessandro Giollo, Davide Gatti, and Maurizio Rossini. "OP0230 EFFECTIVENESS OF INFLUENZA VACCINE IN TNF INHIBITORS TREATED PATIENTS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.3088.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Xiao, Yichen, Han-Ching Ou, Haipeng Chen, Van Thieu Nguyen, and Long Tran-Thanh. "Sequential Vaccine Allocation with Delayed Feedback." In Thirty-First International Joint Conference on Artificial Intelligence {IJCAI-22}. California: International Joint Conferences on Artificial Intelligence Organization, 2022. http://dx.doi.org/10.24963/ijcai.2022/722.

Full text
Abstract:
In this work we consider the problem of how to best allocate a limited supply of vaccines in the aftermath of an infectious disease outbreak by viewing the problem as a sequential game between a learner and an environment (specifically, a bandit problem). The difficulty of this problem lies in the fact that the payoff of vaccination cannot be directly observed, making it difficult to compare the relative effectiveness of vaccination on different population groups. Currently used vaccination policies make recommendations based on mathematical modelling and ethical considerations. These policies are static, and do not adapt as conditions change. Our aim is to design and evaluate an algorithm which can make use of routine surveillance data to dynamically adjust its recommendation. We evaluate the performance of our approach by applying it to a simulated epidemic of a disease based on real-world COVID-19 data, and show that our vaccination policy was able to perform better than existing vaccine allocation policies. In particular, we show that with our allocation method, we can reduce the number of required vaccination by at least 50% in order to keep the peak number of hospitalised patients below a certain threshold. Also, when the same batch sizes are used, our method can reduce the peak number of hospitalisation by up to 20%. We also demonstrate that our vaccine allocation does not vary the number of batches per group much, making it socially more acceptable (as it reduces uncertainty, hence results in better and more interpretable communication).
APA, Harvard, Vancouver, ISO, and other styles
6

Vasileiou, Eleftheria, Colin Simpson, Aziz Sheikh, and Chris Butler. "Seasonal influenza vaccine effectiveness in people with asthma: A systematic review." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa4205.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Gershon, A. S., H. Chung, J. Porter, M. A. Campitelli, S. A. Buchan, K. L. Schwartz, A. Campigotto, et al. "Influenza Vaccine Effectiveness in Older Patients with Chronic Obstructive Pulmonary Disease (COPD)." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2377.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Winthrop, KL, A. Wouters, EH Choy, C. Nduaka, P. Biswas, L. Wang, J. Hodge, et al. "OP0230 The effectiveness of zoster vaccine in RA patients subsequently treated with TOFACITINIB." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2437.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Neminushchaya, L. A., and T. A. Skotnikova. "Improving the effectiveness of vaccine prevention Newcastle disease in the Republic of Tajikistan." In Научные основы производства и обеспечения качества биологических препаратов. Армавир: ФГБНУ Всероссийский научно-исследовательский и технологический институт биологической промышленности, 2021. http://dx.doi.org/10.47804/978-5-89904-0290_2021_103.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Simatupang, Abraham, Robert H. Sirait, Forman Erwin Siagian, Yunita RMB Sitompul, Luana Natingkaseh, and Sudung Nainggolan. "Adverse Events Following Immunization Report and Vaccine Effectiveness of Sinovac. An Interim Report." In 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.211105.036.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Vaccine effectiveness"

1

Berndt, Ernst, Rachel Glennerster, Michael Kremer, Jean Lee, Ruth Levine, Georg Weizsacker, and Heidi Williams. Advanced Purchase Commitments for a Malaria Vaccine: Estimating Costs and Effectiveness. Cambridge, MA: National Bureau of Economic Research, May 2005. http://dx.doi.org/10.3386/w11288.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Alsan, Marcella, and Sarah Eichmeyer. Experimental Evidence on the Effectiveness of Non-Experts for Improving Vaccine Demand. Cambridge, MA: National Bureau of Economic Research, March 2021. http://dx.doi.org/10.3386/w28593.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Russell, Kevin L., Margaret A. Ryan, Anthony Hawksworth, Nikki E. Freed, Marina Irvine, and Luke T. Daum. Effectiveness of the 2003/2004 Influenza Vaccine Among U.S. Military Basic Trainees: A Year of Suboptimal Match Between Vaccine and Circulating Strain. Fort Belvoir, VA: Defense Technical Information Center, June 2004. http://dx.doi.org/10.21236/ada455912.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Paris, Chloe, Julie Spencer, Lauren Castro, and Sara Del Valle. Exploring Impacts to COVID-19 Herd Immunity Thresholds Under Demographic Heterogeneity that Lowers Vaccine Effectiveness. Office of Scientific and Technical Information (OSTI), June 2022. http://dx.doi.org/10.2172/1874147.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Xu, Junjie, Jiaye Liu, Xinquan Lan, Moxin Song, Liangyuan Zhang, and Jiaqi Zhang. Efficacy of the third dose of COVID-19 vaccine: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0114.

Full text
Abstract:
Review question / Objective: To investigate the immune response and related clinical outcomes of healthy adults who received coronavirus vaccine booster compared with those who did not receive the vaccine booster. Condition being studied: The COVID-19 pandemic, which has spread since 2019, has created a huge disease and economic burden on the world. A large number of clinical trials have verified the effectiveness of COVID-19 vaccine. Previous studies have found that the serum conversion rate and antibody level of those vaccinated after the first two doses of COVID-19 vaccine continue to decrease, and the efficacy of the vaccine will decrease over time after the first two doses. Therefore, in order to maintain the protective efficacy of the vaccine, The need for a vaccine booster shot to achieve the expected goal of long-term effective prevention of the novel coronavirus has become a focus of discussion around the world.
APA, Harvard, Vancouver, ISO, and other styles
6

Roldan de Jong, Tamara. Rapid Review: Perceptions of COVID-19 Vaccines in South Africa. SSHAP, April 2022. http://dx.doi.org/10.19088/sshap.2021.021.

Full text
Abstract:
As of April 19, 2021, South Africa has recorded 1.56 million COVID-19 cases and almost 54,000 deaths - more than any other country on the African continent. The country has begun the national rollout of the Johnson & Johnson (J&J) COVID-19 vaccine, with over 292 thousand doses administered it aims to achieve herd immunity by vaccinating at least 67 percent of its population (around 40 million people) by the end of 2021. The government suspended its initial rollout of the AstraZeneca (AZ) vaccine due to concerns over its effectiveness, particularly against the new B.1.351 variant, which accounts for 90% of the infections in South Africa. The J&J vaccine was put on temporary hold in April due to concerns about rare clotting disorders. Although data show that expected acceptance of COVID-19 vaccines is relatively high, the suspension of two vaccines in South Africa, where fear of infection is decreasing, will likely influence public reactions. Understanding how individuals and population groups perceive and make sense of COVID-19 vaccines is critical to inform the design and implementation of risk communication and community engagement (RCCE) strategies, and guide interventions aiming to promote and sustain acceptance of COVID-19 vaccines, while encouraging compliance with other COVID-19 preventive measures. This review syntheses community perceptions of COVID-19 vaccines in South Africa to inform RCCE strategies and policies and provides examples of successful practice. It draws on multiple secondary data sources: scientific literature, qualitative and quantitative studies, grey literature, and mainstream and social media. The review was supported by consultation with four local expert key informants from different fields. It is part of the Social Science in Humanitarian Action Platform (SSHAP) series on social science considerations relating to COVID-19 vaccines. It was written for SSHAP by Tamara Roldan de Jong and Anthrologica on request of the UNICEF South Africa Country Office. Contributions were made from the RCCE Collective Service East and Southern Africa (ESAR) Region. The brief is the responsibility of SSHAP.
APA, Harvard, Vancouver, ISO, and other styles
7

Lamont, Susan J., E. Dan Heller, and Avigdor Cahaner. Prediction of Immunocompetence and Resistance to Disease by Using Molecular Markers of the Major Histocompatibility Complex. United States Department of Agriculture, September 1994. http://dx.doi.org/10.32747/1994.7568780.bard.

Full text
Abstract:
This project utilized two live-animal populations in an integrated research program to identify molecular markers for immune response and disease resistance. The populations each had their foundation from meat-type commercial breeder chicken lines of their respective countries. Investigations effectively used unique availability of resources in each country to study commercial-type environments in Israel and line-crosses with diverse inbred lines in the US. Two bacterial systems were investigated to cover both respiratory and gastrointestinal, and primary and secondary, infections. Individual experimental groups of animals were evaluated for combinations of vaccine antibody levels, response to pathogen challenge, growth parameters, genetic background and molecular markers. The positive association of antibody level with resistance to disease was confirmed. Effectiveness of genetic selection for vaccine antibody response level was demonstrated. Molecular markers, both inside and outside the MHC region, were associated with antibody response and resistance to disease. Markers were shown to have a generalized effect, by association with multiple traits of immune response and disease resistance. The impact of genetic background on marker effect was shown to be important. The overall results demonstrate the effectiveness of selection on vaccine antibody response and the potential of molecular marker-assisted selection to improve efficiency of production of meat-type chickens by reducing genetic susceptibility to disease.
APA, Harvard, Vancouver, ISO, and other styles
8

Jenkins, J. Lee, Edbert B. Hsu, Anna Russell, Allen Zhang, Lisa M. Wilson, and Eric B. Bass. Infection Prevention and Control for the Emergency Medical Services and 911 Workforce. Agency for Healthcare Research and Quality (AHRQ), November 2022. http://dx.doi.org/10.23970/ahrqepctb42.

Full text
Abstract:
Objectives. To summarize current evidence on exposures to infectious pathogens in the emergency medical services (EMS) and 911 workforce, and on practices for preventing, recognizing, and controlling occupationally acquired infectious diseases and related exposures in that workforce. Review methods. We obtained advice on how to answer four Guiding Questions by recruiting a panel of external experts on EMS clinicians, State-level EMS leadership, and programs relevant to EMS personnel, and by engaging representatives of professional societies in infectious diseases and emergency medicine. We searched PubMed®, Embase®, CINAHL®, and SCOPUS from January 2006 to March 2022 for relevant studies. We also searched for reports from State and Federal Government agencies or nongovernmental organizations interested in infection prevention and control in the EMS and 911 workforce. Results. Twenty-five observational studies reported on the epidemiology of infections in the EMS and 911 workforce. They did not report demographic differences except for a higher risk of hepatitis C in older workers and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in minorities. EMS clinicians certified/licensed in Advanced Life Support have a high risk for blood and fluid exposure, and EMS clinicians had a higher risk of hospitalization or death from SARS-CoV-2 than firefighters whose roles were not primarily related to medical care. Eleven observational studies reported on infection prevention and control practices (IPC), providing some evidence that hand hygiene, standard precautions, mandatory vaccine policies, and on-site vaccine clinics are effective. Research on IPC in EMS and 911 workers has increased significantly since the SARS-CoV-2 pandemic. Conclusions. Moderate evidence exists on the epidemiology of infections and effectiveness of IPC practices in EMS and 911 workers, including hand hygiene, standard precautions, mandatory vaccine policies, and vaccine clinics. Most evidence is observational, with widely varying methods, outcomes, and reporting. More research is needed on personal protective equipment effectiveness and vaccine acceptance, and better guidance is needed for research methods in the EMS and 911 worker setting.
APA, Harvard, Vancouver, ISO, and other styles
9

Blackman, Allen, and Bridget Hoffmann. Diminishing Returns: Nudging Covid-19 Prevention Among Colombian Young Adults. Inter-American Development Bank, April 2021. http://dx.doi.org/10.18235/0003223.

Full text
Abstract:
Until a vaccine is widely available, face masks and other nonpharmaceutical interventions (NPIs) will continue to be the frontline defense against Covid-19 in developing countries. But their effectiveness depends critically on compliance by young adults, who are most likely both to become infected and to infect others. We conducted a randomized controlled trial in Bogotá, Colombia, to assess the effectiveness of informational nudges on university students concern about Covid-19, recent compliance with NPI recommendations, and intended future compliance. Although nudges boosted concern, they had limited effects on either recent or intended future compliance. We attribute these null results to high baseline levels of information about and compliance with NPIs an informational diminishing returns scenario that is likely to be increasingly common globally. Nudges were more effective at boosting recent compliance among participants who were politically left-wing, were relatively poor, and lived with more people.
APA, Harvard, Vancouver, ISO, and other styles
10

Millington, Kerry A. Protecting and Promoting Systems for Essential Health Services During Rollout of COVID-19 Tools. Institute of Development Studies (IDS), May 2021. http://dx.doi.org/10.19088/k4d.2021.084.

Full text
Abstract:
The COVID-19 pandemic has had a tremendous negative impact on economies of most countries around the world. COVID-19 has disrupted the ability of health systems to deliver on essential health services and has also exposed pre-existing vulnerabilities and inequities in public health systems. According to a key informant survey conducted by WHO, over one year into the COVID-19 pandemic, there still exist substantial disruptions to essential health services. This rapid review examines evidence on successful interventions that could enable adaptive approaches to help manage and respond future pandemics and mitigate the risk of collapse of the public health systems. Countries must use the opportunity provided by the deployment of COVID-19 vaccines to strengthen health services and health systems and find long-lasting solutions for similar future challenges. The review notes that there still exist gaps in preparedness and response to the Covid-19 pandemic. New variants of concern threaten the effectiveness of existing COVID-19 vaccines, vaccine hesitancy slowing rollout, including in Africa, and interrupted and limited supply of COVID-19 tools. More funding is required though to scale up adaptive measures which are working, accelerating new approaches and innovations to improve service delivery. This review also highlights briefly the plight of marginalised social groups, people living with disabilities, women and children during the pandemic. According to estimates by Global Fund, Gavi, Global Financing Facility, access to life-saving health interventions for women, children and adolescents in 36 of the world’s poorest countries has dropped by as much as 25% due to COVID-19. Countries must build on the momentum of health innovations during the COVID-19 crisis to build more resilient health systems that can withstand disruptions by future pandemics.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Vaccine effectiveness' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography