Academic literature on the topic 'Vaccination'

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Journal articles on the topic "Vaccination"

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Gavin, Regina M., Melanie Countryman, Joseph Musco, Rachel Ricard, Amalia Roberts, and Christine Lees. "Reaching Diverse Communities During a Local Public Health COVID-19 Vaccination Response Through a Mobile Clinic Compared to Mass Vaccination Sites." Journal of Public Health Management & Practice 30, no. 3 (April 10, 2024): 411–15. http://dx.doi.org/10.1097/phh.0000000000001905.

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During the COVID-19 vaccine rollout, local public health agencies were responsible for vaccinating a wide variety of communities. Dakota County Public Health (Dakota County, Minnesota) implemented a program that offered COVID-19 vaccines in a variety of settings, such as county public health buildings, community sites, in-home, mass vaccination clinics, and a mobile clinic unit. The purpose of this analysis is to compare the demographics of vaccinations administered at Dakota County COVID-19 vaccination clinics based on clinic site. More than half (52.5%) of vaccinations administered at mobile clinic sites were administered to Hispanic or Latino clients, while at the mass vaccination clinic site, 5.4% of vaccinations were administered to Hispanic or Latino clients. In addition, 59.6% of in-home vaccinations were administered to adults 65 years and older. Offering COVID-19 vaccination clinics in a variety of clinic settings strategically throughout the community helped increase vaccine reach to diverse communities.
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Gates, Dana M., Steven A. Cohen, Kelly Orr, and Aisling R. Caffrey. "Pharmacist-Administered Influenza Vaccination in Children and Corresponding Regulations." Vaccines 10, no. 9 (August 28, 2022): 1410. http://dx.doi.org/10.3390/vaccines10091410.

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In our retrospective cohort study, we evaluated trends in pharmacist-administered pediatric influenza vaccination rates in the United States and corresponding state-level pharmacist pediatric vaccination authorization models, including minimum age requirements, vaccination protocols, and/or prescription requirements. An administrative health claims database was used to capture influenza vaccinations in children less than 18 years old with 1 year of continuous enrollment and joinpoint regression was used to assess trends. Of the 3,937,376 pediatric influenza vaccinations identified over the study period, only 3.2% were pharmacist-administered (87.7% pediatrician offices, 2.3% convenience care clinics, 0.8% emergency care, and 6.0% other locations). Pharmacist-administered pediatric influenza vaccination was more commonly observed in older children (mean age 12.65 ± 3.26 years) and increased significantly by 19.2% annually over the study period (95% confidence interval 9.2%-30.2%, p < 0.05). The Northeast, with more restrictive authorization models, represented only 2.2% (n = 2816) of all pharmacist-administered pediatric influenza vaccinations. Utilization of pharmacist-administered pediatric influenza vaccination remains low. Providing children with greater access to vaccination with less restrictions may increase overall vaccination rates. Due to the COVID-19 pandemic and the Public Readiness and Emergency Preparedness Act, pharmacists will play a major role in vaccinating children.
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Omae, Yuto, Yohei Kakimoto, Makoto Sasaki, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, and Hirotaka Takahashi. "SIRVVD model-based verification of the effect of first and second doses of COVID-19/SARS-CoV-2 vaccination in Japan." Mathematical Biosciences and Engineering 19, no. 1 (2021): 1026–40. http://dx.doi.org/10.3934/mbe.2022047.

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<abstract><p>As of August 2021, COVID-19 is still spreading in Japan. Vaccination, one of the key measures to bring COVID-19 under control, began in February 2021. Previous studies have reported that COVID-19 vaccination reduces the number of infections and mortality rates. However, simulations of spreading infection have suggested that vaccination in Japan is insufficient. Therefore, we developed a susceptible–infected–recovered–vaccination1–vaccination2–death model to verify the effect of the first and second vaccination doses on reducing the number of infected individuals in Japan; this includes an infection simulation. The results confirm that appropriate vaccination measures will sufficiently reduce the number of infected individuals and reduce the mortality rate.</p></abstract>
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Dońka, Katarzyna, Marlena Suwała, Danuta Zarzycka, Agnieszka Sobolewska-Samorek, and Violetta Paździor. "Vaccine attitudes and education of parents." Pielegniarstwo XXI wieku / Nursing in the 21st Century 17, no. 3 (September 1, 2018): 58–64. http://dx.doi.org/10.2478/pielxxiw-2018-0021.

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AbstractIntroduction.Currently in Poland there is significant differentiation of parents’ attitudes towards vaccinating children. As a consequence, the number of unvaccinated children grows steadily by about 40 percent each year.Aim.Getting to know parents’ attitudes and their causes in relation to immunization based on the analysis of publications on this topic.Material and methods.Selection of publications for analysis was based on criteria of systematic review covering the last 10 years, cataloged in the following databases: Polish Medical Library, Google Scholar and Pubmed. The base searches were carried out according to the key words:protective vaccinations, parents’ attitudes, implementation of the vaccination calendar, immunization, vaccination, parental refusal of vaccines. As many as 32 publications were used in the study.Results.Vaccine knowledge of parents determines their attitude towards vaccination, which influences the implementation of primary and extended vaccinations in children. Implementation of the Protective Vaccination Program remains high in Poland, but the number of parents who refuse to vaccinate their children is systematically growing. Among the many reasons for the refusal of vaccination in children, the most often in literature there were those indicated by barriers of a religious, personal and philosophical nature, security and knowledge on this subject.Conclusions.Low level of parents’ knowledge, both general and specific, about vaccinations is the most common barrier in the implementation of mandatory vaccinations.
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Socha, Anna, and Jörn Klein. "What are the challenges in the vaccination of migrants in Norway from healthcare provider perspectives? A qualitative, phenomenological study." BMJ Open 10, no. 11 (November 2020): e040974. http://dx.doi.org/10.1136/bmjopen-2020-040974.

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BackgroundMigrant populations in the European Union (EU) suffer a disproportionate burden of infectious diseases and may be particularly vulnerable due to poor conditions in countries of origin or throughout transit to the host country. Given the rising level of migration into Europe, the vaccination of migrant populations has become a key priority, with European countries committing to equitably extending the benefits of vaccination to all. However, in Norway, little is known about the vaccination of migrant populations.ObjectiveThe aim of this qualitative research study was to explore the process of vaccinating migrant populations in Norway and elucidate any challenges as perceived by healthcare providers. This involved exploring the challenges faced by healthcare providers in delivering vaccinations to migrants as well as potential barriers faced by migrants in accessing vaccinations in Norway, from the perspectives of healthcare providers.MethodsIn June 2019, the authors conducted semi-structured interviews with seven healthcare providers who are involved in vaccinating migrants in South-Eastern and Western Norway. This included healthcare providers working in general practice, public health and infectious disease clinics, migrant health clinics, and local public health institutes.ResultsAn inductive, exploratory analysis identified key themes that were reviewed and analysed in light of existing literature. According to the informants, the Childhood Immunisation Programme is effective in including migrant children within the national vaccination schedule. However, gaps in vaccination appear to exist with regards to adult migrants as well as working migrants. There is currently no consistent or structured approach to vaccinating adult migrants in Norway, including no guidelines from governing bodies on how to organise vaccination to adult migrants in municipalities. Furthermore, reasons why adult vaccination is not prioritised were provided, such as tuberculosis screening and treatment taking precedence and the common assumption among healthcare providers that vaccinations are dealt with in childhood.ConclusionThe development of equitable immunisation programmes requires an understanding of the multifactorial barriers to immunisation, such as those posed by policies, structures and governance bodies, or lack thereof. It also entails understanding the administration of such policies and the perspectives of those who are responsible for the delivery of vaccination, namely healthcare providers. This qualitative research study demonstrated that challenges exist in the vaccination of migrants in Norway and that they are coherent with those experienced throughout the EU, principally the presence of gaps in vaccinating adult migrants, working migrants and internal EU migrants. This research provides direction for future investigations and highlights the need for the inclusion of migrant status in the Norwegian Immunisation Registry.
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Teo, Ryan Xuan Wei, Bernard Pui Lam Leung, Bernard Yu-Hor Thong, Justina Wei Lynn Tan, Grace Yin Lai Chan, and Xin Rong Lim. "Development of immediate and chronic spontaneous urticaria following mRNA COVID-19 vaccination: Tolerability of revaccination and immunological study." Annals of the Academy of Medicine, Singapore 53, no. 1 (January 30, 2024): 57–59. http://dx.doi.org/10.47102/annals-acadmedsg.2023249.

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Coronavirus 2019 (COVID-19) vaccination remains one of the key public health measures against the SARS-CoV-2 infection, significantly reducing illness severity and mortality rates. Urticaria and/or angioedema are cutaneous reactions that have been reported in response to messenger RNA (mRNA) COVID-19 vaccination and potentially affect fitness for revaccination.1 The development of chronic spontaneous urticaria (CSU) post-COVID-19 vaccination2 may further discourage patients from revaccination or preclude revaccination to keep vaccinations updated. We describe a Singapore case series of 64 patients with urticaria post-COVID-19 vaccination, studying patient tolerance to revaccination, immunological profile and development of CSU.
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Robinson, Stacie J., Michelle M. Barbieri, Samantha Murphy, Jason D. Baker, Albert L. Harting, Meggan E. Craft, and Charles L. Littnan. "Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals." Proceedings of the Royal Society B: Biological Sciences 285, no. 1870 (January 10, 2018): 20171899. http://dx.doi.org/10.1098/rspb.2017.1899.

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Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains rare, providing few opportunities to evaluate performance of model-informed strategies under realistic scenarios. Because the endangered Hawaiian monk seal could be heavily impacted by disease threats such as morbillivirus, we implemented a prophylactic vaccination programme. We used contact networks to prioritize vaccinating animals with high contact rates. We used dynamic network models to simulate morbillivirus outbreaks under real and idealized vaccination scenarios. We then evaluated the efficacy of model recommendations in this real-world vaccination project. We found that deviating from the model recommendations decreased the efficiency; requiring 44% more vaccinations to achieve a given decrease in outbreak size. However, we gained protection more quickly by vaccinating available animals rather than waiting to encounter priority seals. This work demonstrates the value of network models, but also makes trade-offs clear. If vaccines were limited but time was ample, vaccinating only priority animals would maximize herd protection. However, where time is the limiting factor, vaccinating additional lower-priority animals could more quickly protect the population.
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Kowalska, Małgorzata, Maksymilian Gajda, Kamil Barański, and Bogumiła Braczkowska. "Sources of parental knowledge about the safety of vaccinations in Poland." Health Promotion International 34, no. 6 (November 23, 2018): 1191–99. http://dx.doi.org/10.1093/heapro/day096.

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Abstract There has been a recent increase in the number of parents refusing vaccination for their children in many European countries, including Poland. This observation necessitates the need to understand parental knowledge in regard to mandatory vaccination of children in these countries. A cross-sectional survey was conducted in 2016 on 1239 parents or legal guardians of preschool and school children in the Silesian Voivodship (Poland) to evaluate their hesitancy in acquiescing to their children mandatory immunization and the relation to this habit in regard to the use of informational sources on children vaccination system in Poland. Medical doctors often provide the basic source of information about vaccination to parents. About one-third (29%) of the respondents from the survey deemed the qualification system for vaccination as either inadequate or bad. 16.9% of the respondents surveyed declared that information received from physicians regarding vaccinations were either incomplete or unconvincing. Results of multivariable analyses confirmed that respondents are less likely to seek information about mandatory vaccinations from medical professionals and more often to misjudged vaccination’s qualification system. Participants who used less informative sources (e.g. leaflets) and those with a lower level of education were more likely to avoid vaccination. Greater emphasis on the quality of information provided by medical professionals is crucial in order to avoid doubts about vaccination and to create proper attitudes and adherence to vaccination schedules.
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Rista Dwi Lestari, Dina Safira Putri, Dwi Nuning Anggraeny, and Ririn Puspita Tutiasri. "Persepsi Mahasiswa Terhadap Pemberitaan Vaksinasi Covid-19 Pada Media Sosial Instagram." Jurnal ISIP: Jurnal Ilmu Sosial dan Ilmu Politik 18, no. 2 (September 28, 2023): 101–8. http://dx.doi.org/10.36451/jisip.v18i2.58.

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The Covid-19 vaccination activity in Indonesia at the end of 2020 caused a new polemic in the community and gave rise to various positive and negative opinions about vaccination. Experts and public figures explain the importance of vaccinating Covid-19 through their social media accounts. Social media became a medium at the current covid-19 pandemic to share information and policies on Covid-19. The study discussed students’ perceptions in Surabaya of the Covid-19 vaccination information on Dr. Tirta’s social media account. We conducted this study with a qualitative approach and online data-collection technique for interviews with eight student informers over 20-26 years. Studies show that six out of eight informers claim that postings about vaccinations on Dr. Tirta’s Instagram account have significantly been affected by information coupled with accurate data. Dr. Tirta’s covid-19 vaccination information on the student’s Instagram account has a powerful influence on a student’s perception of the Covid-19 vaccination and can transform a student’s actions by willingly vaccinating a Covid-19.
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Wu, Yufei, Huanjie Li, Yangyang Wang, Ping Huang, Yihui Xu, Mingjie Xu, Qianqian Zhao, et al. "Opinion Polls and Antibody Response Dynamics of Vaccination with COVID-19 Booster Vaccines." Vaccines 10, no. 5 (April 20, 2022): 647. http://dx.doi.org/10.3390/vaccines10050647.

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As the third year of the global COVID-19 pandemic, vaccination remains the most effective tool against infections and symptomatic illness. Comprehension regarding immunity to SARS-CoV-2 is limited, and the durability of immune responses after vaccination is currently not clear. In this study, we randomly collected 395 questionnaires to analyze the current state of COVID-19 vaccination. At the same time, the serum of 16 individuals who had received two doses of the COVID-19 vaccine were collected at different times before and after the booster vaccination. We analyzed the dynamic changes of SARS-CoV-2 S-specific binding antibodies in serum and immunological indicators. By collecting public opinion surveys and analyzing variational trends of SARS-CoV-2 S-specific binding antibodies and immune indicators after COVID-19 booster vaccination, we endeavored to demonstrate the concerns affecting people’s booster vaccinations, as well as the frequency, timing, and necessity of COVID-19 booster vaccinations. The analysis of antibody results in 16 vaccinated volunteers showed that the antibody concentration decreased six months after the second dose and the protective effect of the virus was reduced. The third dose of COVID-19 vaccination is necessary to maintain the antibody concentration and the protective effect of the virus. The vaccination with the vaccine booster depends not only on the time interval but also on the initial concentration of the SARS-CoV-2 S-specific binding antibody before the booster. Our study has important implications for raising public awareness of vaccinating against SARS-CoV-2 and the necessity of COVID-19 booster vaccinations.
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Dissertations / Theses on the topic "Vaccination"

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Brisson, Marc. "Economic evaluation of vaccination programmes : a special reference to varicella vaccination." Thesis, City University London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407544.

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Hamilton, Carly Anne. "Neonatal vaccination : role for innate immune cell interactions in BCG vaccination." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22079.

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Bovine tuberculosis (TB), caused by Mycobacterium bovis, is increasing in incidence in the United Kingdom and detailed knowledge of host-pathogen interactions in the natural host is essential to facilitate disease control. Vaccination of neonatal calves with Bacille Calmette Guerin (BCG) induces a significant level of protection from infection with M. bovis. Since neonatal vaccination of humans with BCG induces activation of natural killer (NK) cells, and neonatal calves have high circulating numbers of these cells, it is proposed that NK cells are important in the response to BCG. Furthermore, NK cells play an important role in shaping adaptive immune responses through interactions with dendritic cells (DCs). The overall hypothesis of this project was that the enhanced efficacy of BCG in neonates is due to the increased number of NK cells, which through interactions with DCs can polarise Th1-type CD4+ and CD8+ T cell responses, both of which are involved in protection against M. bovis infection. Initially, the frequency and phenotype of NK cells across the blood, afferent lymph and the lymph nodes in steady-state conditions were compared. CD2- NK cells were the principal subset of NK cells migrating from the skin to the draining lymph node and were highly activated in afferent lymph and lymph nodes, compared with peripheral blood. It was also demonstrated that CD2- NK cells were the main subset of NK cells egressing from the lymph node via the efferent lymphatic vessel to return to circulation. Since many vaccines including BCG are delivered subcutaneously, NK cell responses in the blood and the skin draining afferent lymphatic vessel, lymph nodes and efferent lymphatic vessel were determined after BCG vaccination. Alterations in the frequency and receptor repertoire were evident following vaccination, supporting a role for NK cells during BCG vaccination of neonatal calves. To investigate the interactions of NK cells and BCG-infected DCs, in vitro co-cultures were established. CD2- NK cells were preferentially activated following culture with BCG-infected DCs and secreted high levels of IFN-γ. Overall, this thesis provides novel evidence that NK cells may re-circulate in steady-state conditions, play a role in BCG vaccination of neonatal calves, and that through interactions with BCG-infected DCs, may be involved in driving protective Th1-type adaptive immune responses.
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Dannetun, Eva. "Reasons for non-vaccination /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-739-1/.

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Leach, Richard Jonathan. "Genetics of bovine vaccination." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5018.

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Infectious disease is an important issue for animal breeders, farmers and governments. Solutions to control infectious disease are needed and research focused on the genetic loci determining variation in immune-related traits has the potential to deliver solutions. The primary aim of this thesis is to discover regions of the bovine genome which influence the immune response post immunisation. To accomplish this two types of immunising agents, a Foot-and-Mouth Disease Virus (FMDV) peptide (FMDV15) and a commercial vaccine for Bovine Respiratory Syncytial Virus (BRSV), were used to immunise the second generation (F2 and backcrosses) of the Roslin Bovine Genome (RoBoGen) herd, a Charolais Holstein cross population. The FMDV15 peptide consisted of two sections of the VP1 protein located on the FMDV capsid, together encompassing the major neutralising antibody sites that are known to be immunogenic. Protection against FMDV is generally believed to relate to the levels of neutralising antibody and has been correlated with IgG1 and IgG2 levels as well as interferon- . In addition it has been shown that T cell responses also play a role in protection against FMDV. Thus all of these were used as phenotypic measurements post immunisation to the FMDV15 peptide. The BRSV vaccine used was an attenuated live vaccine. Protective mechanisms against BRSV infection include IgA, IgG1, IgG2 and IgM BRSV-specific antibodies and antibody titres particularly those of the IgG isotypes are considered to be correlates of protection. Thus, IgG1 and IgG2 antibody levels were measured post vaccination with the BRSV vaccine. All phenotypes were measured across time, and allowed analysis of the primary and secondary adaptive immune responses. Both agents caused considerable variation in the phenotypes measured post immunisation, with significant responses detected two weeks post immunisation. REstricted Maximum Likelihood (REML) analysis attributed much of this variation to sire, highlighting the heritable component, and environmental effects. Significant positive correlations were detected across time within each trait for both the FMDV and BRSV responses. The FMDV and BRSV antibody levels also correlated with each other at later time points, suggesting that there may be animals which are genetically predisposed to be high or low responders in general. Initially a linkage mappingapproach was followed using 165 microsatellite markers, which detected 77 QTL in response to the FMDV peptide and 27 QTL in response to the BRSV vaccine. There were some overlapping QTL, for example QTL which spanned the Major Histocompatibility Complex. Further analysis was conducted by developing a Perl scripted program which genotyped the RoBoGen herd in two ways; 1) Single Nucleotide Polymorphism(s) (SNP) were genotyped within the confidence intervals of the previously discovered QTL and 2) SNP were genotyped via a candidate gene approach. Association study methodology, accounting for relationship stratification via principal components of the genetic relationship matrix, was used to detect significant SNP, in response to both the FMDV peptide and the BRSV vaccine. Twenty significant SNP associations were discovered across 19 traits, with some SNP located in genes with known biological relevance to an immune response, such as the Toll-Like Receptors (TLR), TLR4 and TLR8. This thesis has detected regions of the genome which are significantly associated with the immune responses elicited by two different agents, suggesting similar pathway(s)/gene(s) may be used in defence of multiple pathogens. Once regions of significance were detected, further analysis using SNP markers identified significant, non-synonymous SNP that were associated with the immunising agents. The novel markers discovered in this study may aid breeding for resistance to disease via marker assisted selection. In addition, they may also have highlighted new targets for vaccinologists to develop ‘next generation’ vaccines.
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Campbell, John P. "Behavioural adjuvants to vaccination." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/830/.

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This thesis investigated the effects of acute eccentric exercise on the immune response to vaccination in young humans. Study one investigated whether the efficacy of the eccentric exercise intervention was affected by manipulating the timings of exercise prior to influenza vaccination. Three exercise groups were vaccinated immediately, 6 hr or 48 hr after exercise and antibody responses at 28 days post-vaccination were compared to those from a resting control group. All participants exhibited robust antibody responses to the vaccine and no effect of exercise was observed; therefore, it was not possible to determine the effects of exercise timing on vaccine responses. Study two investigated whether the antibody response to influenza vaccination was influenced by the intensity of eccentric exercise. Three groups exercised at an intensity eliciting 60%, 85% or 110% of one repetition maximum, and the antibody responses at 28 days post-vaccination were compared to those from a resting control group. In the exercise groups, both men and women showed enhanced antibody responses against the B/Florida strain, and men had enhanced responses against A/Uruguay, in comparison to resting controls. In both cases, the control group exhibited poorer responses against these strains, but no effect of exercise intensity was observed. Study three investigated whether the site of vaccine administration affected the efficacy of the immune response to hepatitis B vaccination following eccentric exercise. The antibody seroconversion rate to the vaccine was low (approx. 5 %), and thus, further analysis between exercise and control participants was not feasible. In sum, supporting previous research, it appears that acute eccentric exercise can enhance the immune response to poorly immunogenic strains of influenza, but research is needed to establish if exercise can enhance other poorly immunogenic vaccines, or vaccine responses in the immuno-compromised.
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Di, Genova Gianfranco. "Vaccination and immunological memory." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/63837/.

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Human subjects maintain long-term immunological memory against infective organisms but the mechanism is unclear. CD4+ T helper memory cells (Thmem) are pivotal in controlling humoral and cellular responses, therefore their longevity and response to vaccination are critical for maintenance of protective immunity. To probe the dynamics of the Thmem response to antigenic challenge, we investigated subjects following a booster injection with tetanus toxoid (TT). Expansion of TT-specific Thmem cells, and cytokine production, showed complex kinetics. Strikingly, parallel expansion and cytokine production occurred in pre-existing Thmem cells specific for two other common antigens, Purified Protein Derivative of tuberculin (PPD), and Candida albicans (C.alb). Bystander expansion occurred in Thmem but not in Thnaive cells. Antibody production against TT peaked ~2 weeks post-vaccination and gradually declined. However, pre-existing antibody against the other antigens did not change. It appears that, although all Thmem cells are readily stimulated to expand, antibody responses are controlled by antigen availability. These human findings which relate to the maintenance of memory and have consequences for assessments of specific T-cell responses to vaccination, have been further investigated in a mouse model. A transgenic model (OT-II) where CD4+ T cells express a TCR specific for an ovalbumin peptide (peptide 323-339, OVAp) was used first to ask the question as to whether naïve or antigen-activated T cells were influenced in a bystander manner during a secondary immune response directed against a protein antigen that was unrelated to their cognate one. For this, carboxyfluorescein diacetate succunimidyl ester (CFSE)-labeled OT-II cells were adoptively transferred, either as naïve or 4 following in vitro activation with OVAp, into C57/BL6 wild type recipient mice which were immune to TT. Recipient mice were then challenged with TT antigen and susceptibility of OT-II cells to bystander activation and proliferation was tested. Naïve T cells were found not to be influenced, but antigen-activated cells were responsive and underwent further activation and bystander proliferation, with accompanying phenotypic changes. Interestingly bystander proliferation appeared to be proportional to the strength of TT-specific cellular immune response. The second question was whether the bystander influence on activated T cells was also evident during a primary immune response to TT. To address this question, antigen-activated OT-II cells and control naïve cells were adoptively transferred into wild type naïve recipient mice and their activation and proliferation was assessed after challenge with TT. In this case no bystander activation or proliferation of OT-II cells was observed. These results underline the susceptibility to bystander activation and proliferation as a unique feature of antigen-activated OT-II cells as opposed to naïve OT-II cells. They mirror those obtained in our study on human subjects and add formal proof of bystander proliferation occurring in vivo. Furthermore this well defined mouse model paves the way for further investigations aimed at addressing the mechanisms responsible for the observed phenomenon.
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Montmartin, Philippe. "Tolérance de la vaccination anti-grippale : à propos d'une étude rétrospective sur 741 vaccinations, dans le département de la Loire." Saint-Etienne, 1994. http://www.theses.fr/1994STET6226.

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Sundberg, Mikael. "Misstro mot vaccination i modern kommunikation : Kvantitativ analys av Facebookgruppen "Stop Mandatory Vaccination"." Thesis, Högskolan i Gävle, Avdelningen för humaniora, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-30388.

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Syften med uppsatsen var att ta reda på hur folk som är en del av anti-vaccinationsrörelsen kommunicerar i sociala medier. Uppsatsen undersöker hur de kommunicerar i inlägg och kommentarer i en sluten grupp på Facebook. Med hjälp av ett kodschema så blev 97 inlägg analyserade och placerad i olika kategorier med olika variabler. Utifrån kodschemat blev flera tabeller skapade som visade den mest relevanta faktan. Utifrån den information, och med flera detaljerat beskriva exempel-inlägg, beskrivs den generella stämningen i gruppen och hur de talar med varandra. Resultatet blev att de kommunicerar med varandra på ett vänligt och stöttande sätt, bidrar med relevant information när det frågas efter, men med lite fientlighet visas mot de som kommer med motsatta åsikter. Gruppen var sluten, vilket innebär att bara individer som delar samma åsikter som dem är medverkande på plattformen, vilket också betyder att åsikter blir så gott som aldrig utmanade.
The purpose of this essay has been to figure out how people that are a part of the anti-vaccination movement communicate in social media. The essay explores how they communicate in posts and comments in a closed group on Facebook. With the help of a coding scheme, 97 posts became analysed and placed in different categories with different variables. A couple of tables were created from the code scheme that demonstrated the most relevant facts. From that information, and with several detailed descriptions of example posts, describes the general mode in the group and how they speak with each other. The result was that they communicate with each other in a nice and supporting way, contribute with relevant information when it was asked for, but with some hostility shown towards those who come with opposite views. The group was closed, which means that only individuals who share the same views as them are involved with the platform, which also means that opinions are almost never challenged.
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Bravetti, Vincent Birgé Jacques. "Statut vaccinal diphtérie, tétanos, poliomyélite, coqueluche et hépatite B de l'adolescent et l'adulte jeune premier tour d'audit auprès de 49 médecins généralistes lorrains /." [S.l.] : [s.n.], 2007. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2007_BRAVETTI_VINCENT.pdf.

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Dulude, Alexandra. "CANCER PATIENT ATTITUDES TOWARDS INFLUENZA VACCINATION AND THE PREVALENCE OF VACCINATION IN CANCER PATIENTS." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/528169.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.
Introduction: Thousands of people die from influenza or its complications each year despite the fact that it is one of the few vaccine preventable diseases. Immunocompromised cancer patients are among the most vulnerable to this infection and flu‐related complications, and therefore vaccination is highly recommended in these patients; however, current vaccination rates and attitudes towards vaccination remain unknown. We hypothesize that immunization rates are lower than the 100% recommendation rate, and hope to understand the reasoning behind the discrepancy. The purpose of this study is to assess cancer patient attitudes towards influenza vaccination in an effort to minimize barriers to vaccination and eventually increase vaccination rates in this immunocompromised population. Methods: Cancer patients enrolled in phase I clinical oncology trials at the Virginia G Piper Cancer Center at Scottsdale Healthcare were invited to participate in a voluntary survey. The 15‐item survey consisted of demographic information, knowledge regarding the flu vaccine, vaccination status after cancer diagnosis and while on treatment, and general attitudes towards vaccination. A total of 84 cancer patients completed the survey. Results were stratified by age, gender, education level, and vaccination status. As this was a descriptive study, no statistical analyses were performed. Results: A total of 84 (n=84) advanced cancer patients enrolled in phase I clinical oncology trials completed the survey. Results indicate that although 71% of patients received the vaccine prior to cancer diagnosis, only 58% of patients have received the vaccine since their cancer diagnosis, and only 48% have been vaccinated while on cancer treatment. Of those vaccinated since cancer diagnosis, 94% reported doctor recommendation of the vaccine and most vaccinate to protect themselves from the virus. Of those not vaccinated since cancer diagnosis, only 37% report their doctor recommends the vaccine and the majority avoid vaccination because they believe the vaccine can cause the flu, they do not feel at risk of infection, and they do not believe the vaccine is effective. Conclusion: Our findings suggest that although the CDC strongly recommends influenza vaccination in cancer patients due to the risk of secondary complications and even death in these immunocompromised individuals, vaccination rates remain low. Our data demonstrates that patients who receive a doctor recommendation for the vaccine are more likely to be vaccinated, but not all doctors recommend the vaccine. Furthermore, false information regarding the vaccine, its efficacy, and its ability to cause infection continues to deter patients from vaccination. Together, this information offers profound insight into the cancer patient population and suggests the need for increased physician and patient education regarding the benefits of annual influenza vaccination to improve vaccination rates and decrease influenza infection and complications in the future.
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Books on the topic "Vaccination"

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Koprowski, Hilary, and David B. Weiner, eds. DNA Vaccination/Genetic Vaccination. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80475-5.

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Ellis, Anthony E. Fish vaccination. Aberdeen: Department of Agriculture and Fisheries for Scotland, Marine Laboratory, 1989.

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E, Ellis A., ed. Fish vaccination. London: Academic Press, 1988.

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Vaccinating Britain: Mass Vaccination. Manchester University Press, 2019.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Pet Vaccination Record Book: Pet Vaccination Record, Vaccination Record, Pet Vaccinations Log Book, Vaccine Book. Independently Published, 2021.

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Book chapters on the topic "Vaccination"

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de Miguel Beriain, Iñigo. "Vaccination (II): Vaccination Policies." In The Ethical, Legal and Social Issues of Pandemics, 73–105. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-03818-1_4.

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Al Mazrou, Abdulrahman M. "Vaccination." In Textbook of Clinical Pediatrics, 929–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02202-9_76.

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Pentel, Paul R., Mark G. LeSage, Mark G. LeSage, Paul R. Pentel, Lawrence H. Price, Tomasz Schneider, Maria-Inés López-Ibor, et al. "Vaccination." In Encyclopedia of Psychopharmacology, 1355. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_913.

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Afolabi, Michael O. S. "Vaccination." In Encyclopedia of Global Bioethics, 2911–18. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-09483-0_432.

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Afolabi, Michael Olusegun. "Vaccination." In Encyclopedia of Global Bioethics, 1–9. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-05544-2_432-1.

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Schnieder, Thomas, Dania Richter, Luiz Hildebrando Pereira da Silva, and Charlotte Behr. "Vaccination." In Encyclopedia of Parasitology, 2983. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3354.

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Varga, Gergely. "Vaccination." In The Palgrave Encyclopedia of Global Security Studies, 1–5. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-74336-3_561-1.

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Jaspreet, Dhami, Wang Vivian, Wang Ziwei, Pham Brittney, Yabuno Jamie, and Joseph Yusin. "Vaccination." In Absolute Allergy and Immunology Board Review, 307–15. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-12867-7_30.

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Klimov, Vladimir V. "Vaccination." In From Basic to Clinical Immunology, 291–304. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03323-1_8.

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Andersson, Håkan, and Tom Britton. "Vaccination." In Stochastic Epidemic Models and Their Statistical Analysis, 117–25. New York, NY: Springer New York, 2000. http://dx.doi.org/10.1007/978-1-4612-1158-7_12.

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Conference papers on the topic "Vaccination"

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Saraswat, Avani, and Tejal Varekar. "Analyzing the Effectiveness of Vaccination as a Preventive Measure in Combating COVID-19 and Recommendations for Future Health Emergencies in India." In 4th International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2023. http://dx.doi.org/10.32789/publichealth.2022.1003.

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In order to mitigate the impact of the COVID-19 pandemic, India launched the world’s most extensive vaccination drive. Almost 1.9 billion vaccination doses were given until May 13, 2022, since the beginning of the drive, with 1 billion people vaccinated for the first dose and 0.87 billion people for the second dose. The objective of the study is to analyze the impact of vaccination on the control of SARS-CoV-2 infection. The secondary data was obtained by the World Health Organization for COVID-19 cases and the Ministry of Health and Family Welfare for vaccination from January 22, 2022, to May 13, 2022. Exponential regression was performed for total cumulative vaccinations (18 years and older received at least one dose) as an independent variable and the rate of COVID infection (0.1million per week) as a dependent variable. The p-value is 0.001, with a negative slope emphasizing that the correlation is significant for the selected time period. Further, the predictive model with R2 = 0.96 shows the model is best fitted. The mathematical model supports the role of vaccination in decreasing cases of COVID-19. Predicting the rate of occurrence of infection against the backdrop of a vaccination drive can be a valuable tool for assessing vaccine effectiveness and planning for future actions. Keywords: COVID-19, vaccination, health emergencies, preventive measures
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Uz Zaman, Farhan, Tanvinur Rahman Siam, and Zulker Nayen. "Prediction of Vaccination Side-Effects using Deep Learning." In 2nd International Conference on Machine Learning Techniques and NLP (MLNLP 2021). Academy and Industry Research Collaboration Center (AIRCC), 2021. http://dx.doi.org/10.5121/csit.2021.111424.

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Deep learning has been very successful in the field of research which includes predictions. In this paper, one such prediction is discussed which can help to implement safe vaccination. Vaccination is very important in order to fight viral diseases such as covid-19. However, people at times have to go through unwanted side effects of the vaccinations which might often cause serious illness. Therefore, modern techniques are to be utilised for safe implementations of vaccines. In this research, Gated Recurrent Unit, GRU, which is a form of Recurrent Neural Network is used to predict whether a particular vaccine will have any side effect on a particular patient. The extracted predictions might be used before deciding whether a vaccine should be injected to a particular person or not.
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"Was there a difference in the COVID-19 symptoms among Ghor Elsafi population either before or after receiving the COVID-19 vaccines?" In International Conference on Public Health and Humanitarian Action. International Federation of Medical Students' Associations - Jordan, 2022. http://dx.doi.org/10.56950/pzez3624.

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Introduction: COVID19 vaccination had high positive results on infections worldwide. Even if someone has been infected after the vaccination; it will be less severe symptoms and will have a better prognosis. The aim: To assess the COVID-19 clinical presentation, the vaccination status and the need for hospitalization both before and after vaccination among Ghor ELSafi residents. Materials and methods: A community-based study was conducted in Ghor ElSafi, al-Karak, Jordan. A questionnaire was conducted on the google form. A total of 101 participants were classified into: first group (n = 58) (Participants infected before COVID-19 vaccination) and second group (n = 43) (participants infected at least 2 weeks after COVID-19 vaccination). Demographic data, History of SARS-CO2 infection and vaccination, Different COVID-19 symptoms, hospitalization, ICU admission and oxygen therapy need were assessed for all participants. Results: All participants were COVID-19 vaccinated. The mean age was 38 (±12.3) years with 51.9% was males. About 32.6% had comorbidities. There was no significant differences between both groups regarding the prevalence of either general, gastrointestinal, respiratory, cardiovascular or gynecological symptoms (Figure 1). There were variations in some COVID-19 symptoms; Group (1) participants had a higher rate of anosmia/ageusia, a lower rate of sneezing and dry cough than Group (2). About 12.9% of participants required hospitalization, 7 participants required O2 therapy, and 2 were admitted to the ICU. The mean hospital stay was 7.38 (±6.16) days without statistical significant difference between both groups. Conclusions: most of the COVID symptoms were statistically non-significant between pre-vaccinated and post-vaccination groups, except few symptoms. Participants who got infected before vaccination had a higher rate of anosmia/ageusia, a lower rate of sneezing and dry cough. Keywords: COVID19, Vaccinations, clinical symptoms
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Seck, E. S., L. Schönborn, and A. Greinacher. "Subsequent vaccinations in VITT patients other than SARS-CoV2 vaccination." In GTH Congress 2023 – 67th Annual Meeting of the Society of Thrombosis and Haemostasis Research – The patient as a benchmark. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0042-1760581.

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Deininger, Layza de Souza Chaves, Aralinda Nogueira Pinto de Sá, Mônica de Almeida Lima Alves, Quênia Gramile Silva Meira, and Carolina Carvalho Nogueira. "University extension work to encourage multivaccination in primary health care." In III SEVEN INTERNATIONAL MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/seveniiimulti2023-152.

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The involvement of students in extension provides training for citizen professionals in society and is a privileged space for the production of knowledge to overcome existing social inequalities. The aim of this study is to present the experience of university extension in encouraging multivaccination in primary health care. The study is an experience report carried out between February and May 2023 with medical students at a Family Health Unit (USF). Upon identifying the health need in the area of low vaccination coverage, the students planned, together with the team's health professionals, the best ways to delight and sensitize the community about the importance of updating the vaccination card in all age groups. Among the strategies, a video was recorded calling the population to D-Day for multivaccination, which was broadcast on community radio. On the day of the event, the students organized themselves into small groups and developed fun activities such as games, bingo and raffles; they distributed snacks and food baskets, as well as supporting the team in the active search of the area. Thus, the inventiveness of walking through the streets with a loudspeaker and wearing superhero, princess and Ze Gotinha costumes got the community moving, engaging both children and their parents to seek vaccination. The creative choices in the D-Day multi-vaccination campaign generated an intense and continuous flow in the service, which had a positive impact on achieving the targets for routine vaccinations, as more than 87 children and adults updated their vaccination cards in just one shift. The success of the activity was evident and the report was one of personal and professional fulfillment. Thus, the importance of university extension was observed, both for professionals and the community, as well as for the students in terms of sharing experiences and care.
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Kekre, H. B., Sudeep D. Thepade, Anant Shah, Prathamesh Verlekar, and Suraj Shirke. "Network vaccination architecture." In the International Conference. New York, New York, USA: ACM Press, 2009. http://dx.doi.org/10.1145/1523103.1523205.

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Spencer, Julie, Manhong Smith, David Osthus, Matthew Biggerstaff, and Sara Del Valle. "Influenza Vaccination Timing." In SMB MathEpiOnco 2024 ; 2024-02-18 - 2024-02-19 ;. US DOE, 2024. http://dx.doi.org/10.2172/2337622.

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Matīse-Van Houtana, Ilze. "Attitudes and Opinions of Veterinary Professionals About Covid-19 Infection and Vaccination Against It." In International scientific conference of the University of Latvia. University of Latvia Press, 2023. http://dx.doi.org/10.22364/ms22.09.

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Veterinarians are well trained to recognize and control infectious diseases and use vaccination as a routine procedure for preventing infectious diseases in animals. This role of veterinarians has become more emphasized since acceptance of concept “One world – one health” by health professions in medical and veterinary fields. It would be expected that veterinarians are well-prepared to form a scientifically based opinion on Covid-19 and on value of vaccination against it at individual and society level. The goal of this study was to determine whether and to what extent veterinary medical knowledge and experience influences beliefs, attitudes and actions towards Covid-19 and vaccination at individual and society levels. To address this goal, structured, anonymous interviews were conducted in March 2022 with volunteers representing veterinary professionals (n = 14). Results showed that veterinary professionals represented a divided community of people. While majority (almost 80%) of veterinary professionals voluntarily chose to be vaccinated and believed that Covid-19 is dangerous to their health and society as a whole, there were 2 respondents that believed in conspiracy theories, 2 that did not think that Covid-19 was substantial threat to them or society, and 3 that refused or were reluctant to get vaccinated. There was a direct correlation between believing in conspiracy theories and vaccine-hesitancy. Personal experience having severe illness caused by Covid-19 did not change beliefs. There was no direct correlation between support for animal vaccinations and support for vaccination against Covid-19. Overall, these results show that veterinary professionals in Latvia are not particularly different from Latvian society in general. Presence of supporters of conspiracy theories and vaccine-sceptics among veterinarians indicate that there are factors besides professional public health training and education (university degree and even PhD) that influence establishment of personal beliefs and attitudes.
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Zainafree, Intan, Chatila Maharani, Nadia Syukria, Fitri Indrawati, Bambang Raharjo, Bambang Wahyono, Mohammad Hakam, et al. "Society’s Perspective on Implementation of Vaccination at the Semarang Vaccination Centers." In Proceedings of the 6th International Seminar on Public Health and Education, ISPHE 2022, 29 June 2022, Semarang, Central Java, Indonesia. EAI, 2023. http://dx.doi.org/10.4108/eai.29-6-2022.2326134.

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Zhang, Chijun, Qianyun Fu, and Ruihong Zhou. "Layered Vaccination Strategy Study." In 2017 IEEE International Conference on Computational Science and Engineering (CSE) and IEEE International Conference on Embedded and Ubiquitous Computing (EUC). IEEE, 2017. http://dx.doi.org/10.1109/cse-euc.2017.232.

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Reports on the topic "Vaccination"

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Oster, Emily. Does Disease Cause Vaccination? Disease Outbreaks and Vaccination Response. Cambridge, MA: National Bureau of Economic Research, July 2016. http://dx.doi.org/10.3386/w22464.

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Stein, Stanley, and Michael J. Leibowitz. Autologous Tumor Vaccination. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada407668.

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Lewin, Simon, Sebastián García Martí, Agustín Ciapponi, Shaun Treweek, and Andy Oxman. What are the effects of interventions to improve childhood vaccination coverage? SUPPORT, 2016. http://dx.doi.org/10.30846/16081605.

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Routine vaccination during childhood is considered to be the single most effective way of controlling many infectious diseases, including measles, polio, diphtheria, pertussis and tetanus, and reducing child mortality and morbidity. However, not all children receive their recommended vaccinations. Different approaches that aim to increase childhood vaccination coverage include health education, monetary incentives for clients, provider oriented interventions, system interventions such as integration, home visits and reminders for parents.
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Tadros, Mariz, and Claire Thomas. Evidence Review: Religious Marginalities and COVID Vaccination - Access and Hesitancy. Institute of Development Studies (IDS), September 2021. http://dx.doi.org/10.19088/sshap.2021.033.

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Religious minority affiliation or status can play a very important role in influencing people's access to vaccines as well as their willingness to undergo vaccination. Many studies focus on class, ethnicity and geographic location when examining how social inequalities impact vaccination programmes. However, religious marginality is often overlooked. Here we explore how being situated on the margins, on account of religious affiliation, shapes experiences of vaccine access and uptake. The issues addressed are important for COVID-19 vaccination roll out, but also contain lessons for all vaccination programmes and many other preventative health measures. In this brief, we present key considerations for addressing differentials in access to and willingness to undergo vaccinations that are linked to religious minority status, experiences, authorities or doctrine. We explain why the study and awareness of religious marginality is crucial for the success of vaccination programmes broadly and specifically as they apply to COVID-19 vaccination. We also explore ways in which religious marginality intersects with other identity markers to influence individual and community access to vaccines. Finally, we examine vaccine hesitancy in relation to religious minorities and outline approaches to community health engagement that are socio-religiously sensitive, as well as practical, to enhance vaccination confidence.
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Tadros, Mariz, and Claire Thomas. Evidence Review: Religious Marginalities and COVID Vaccination - Access and Hesitancy. Institute of Development Studies (IDS), November 2021. http://dx.doi.org/10.19088/sshap.2021.043.

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Religious minority affiliation or status can play a very important role in influencing people's access to vaccines as well as their willingness to undergo vaccination. Many studies focus on class, ethnicity and geographic location when examining how social inequalities impact vaccination programmes. However, religious marginality is often overlooked. Here we explore how being situated on the margins, on account of religious affiliation, shapes experiences of vaccine access and uptake. The issues addressed are important for COVID-19 vaccination roll out, but also contain lessons for all vaccination programmes and many other preventative health measures. In this brief, we present key considerations for addressing differentials in access to and willingness to undergo vaccinations that are linked to religious minority status, experiences, authorities or doctrine. We explain why the study and awareness of religious marginality is crucial for the success of vaccination programmes broadly and specifically as they apply to COVID-19 vaccination. We also explore ways in which religious marginality intersects with other identity markers to influence individual and community access to vaccines. Finally, we examine vaccine hesitancy in relation to religious minorities and outline approaches to community health engagement that are socio-religiously sensitive, as well as practical, to enhance vaccination confidence.
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Frankel, Jeffrey, and Randy Kotti. The Virus, Vaccination, and Voting. Cambridge, MA: National Bureau of Economic Research, August 2021. http://dx.doi.org/10.3386/w29186.

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Egilmez, Nejat K. Tumor Vaccination With Cytokine-Loaded Microspheres. Fort Belvoir, VA: Defense Technical Information Center, December 2005. http://dx.doi.org/10.21236/ada457688.

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Wei, Wei-Zen. DNA Vaccination to Overcome Peripheral Tolerance. Fort Belvoir, VA: Defense Technical Information Center, August 2004. http://dx.doi.org/10.21236/ada428423.

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McBride, William H. Radiation-Induced Vaccination to Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada614132.

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Wei, Wei-Zen. DNA Vaccination of Overcome Peripheral Tolerance. Fort Belvoir, VA: Defense Technical Information Center, August 2002. http://dx.doi.org/10.21236/ada411427.

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