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Published: 11 March 2023

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1

Giovannelli, G. "Conferenze.: Uropatie Malformative." Urologia Journal 58, no. 2 (April 1991): 200–206. http://dx.doi.org/10.1177/039156039105800210.

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2

Hong, Lih En, Chrismin Tan, and Jordan Li. "Obstructive Uropathy Secondary to Uretero-inguinal Hernia." Journal of Clinical Imaging Science 5 (June 29, 2015): 33. http://dx.doi.org/10.4103/2156-7514.159448.

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Uretero-inguinal hernia in patients with native kidneys is rare. We report a case of an 84-year-old man who was diagnosed with obstructive uropathy secondary to uretero-inguinal hernia, with no past history of herniorrhaphy or congenital genitourinary malformation. Uretero-inguinal hernias are predominantly indirect inguinal hernias and may be paraperitoneal or extraperitoneal. Computed tomography (CT) is a non-invasive diagnostic tool for uretero-inguinal hernia. Herniorrhaphy is indicated in all cases of uretero-inguinal hernia to prevent obstructive uropathy.
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3

Virgilio, Robson Cristian, Fernanda Monteiro Orellana, Luiz Felipe De Melo Pereira Leitão, Tiago Granucci Guirro, Rafael Freitas de Andrade Neri, Pablo Leonardo Traete, Pedro Ivo Ravizzini, and Luis Gustavo Morato de Toledo. "Tratamento laparoscópico de cálculo ureteral em ureter retrocava / Laparoscopic treatment of ureteral stone in retrocaval ureter." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 66, no. 1u (May 27, 2021): 1. http://dx.doi.org/10.26432/1809-3019.2021.66.014.

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Introdução: O ureter retrocava é uma malformação congênita rara que pode ser causa de uropatia obstrutiva com sintomas inespecíficos como dor lombar e complicações como ureterolitíase e pielonefrite, que normalmente aparecem entre a terceira e a quarta décadas de vida, e exige tratamento cirúrgico na maior parte dos casos. Objetivo: Apresentar um caso de ureter retrocava associado a ureterolitíase e uma revisão da literatura a respeito das técnicas cirúrgicas para sua correção. Relato de caso: Os autores apresentam um caso de ureterolitíase e ureter retrocava, diagnosticado por tomografia computadorizada, em um paciente masculino de 43 anos com dor lombar direita, corrigido através de técnica laparoscópica transperitoneal. Conclusão: A correção cirúrgica laparoscópica do ureter retrocava tem se mostrado benéfica em diversos aspectos quando comparada ao acesso aberto e uma abordagem que ainda não havia sido publicada é a correção do ureter retrocava associado a ureterolitíase num mesmo tempo cirúrgico. Palavras chave: Ureter retrocava, Hidronefrose, Ureterolitíase, Anomalia urogenital, Laparoscopia ABSTRACT:Introduction: The retrocaval ureter is a rare congenital malformation which may cause obstructive uropathy with nonspecific symptoms such as low back pain and complications as ureterolithiasis and pyelonephritis, which usually appear between the third and fourth decades of life, and requires surgical treatment in most cases. Objective: To present a case of ureterolithiasis and retrocaval ureter and a review of literature, regarding the different types of access for his surgery. Case Report: The authors present a case of ureterolithiasis and retrocaval ureter diagnosed by computed tomography in a 43-year-old male patient with right lower back pain, corrected using a transperitoneal laparoscopic technique. Conclusion: Laparoscopic surgical correction of the retrocaval ureter has shown to be beneficial in several aspects when compared to open access, and one that has not been previously reported is the one-step resolution of the association with ureterolithiasis.Keywords: Retrocaval ureter, Hydronephrosis, Ureterothiasis, Urogenital abnormalities, Laparoscopy
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4

Costa, Guilherme Henrique Freire, Vitor Doria Ricardo, Jean Lucas Benatti, Juliana Lucena Queiroz, Danilo Gagliardi, José Carlos Esteves Veiga, and Celso De Castro Pochini. "Exteriorização de material cirúrgico em luz esofageana / Exteriorization of surgical material in esophagus lumen." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 66, no. 1u (May 27, 2021): 1. http://dx.doi.org/10.26432/1809-3019.2021.66.013.

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Introdução: O ureter retrocava é uma malformação congênita rara que pode ser causa de uropatia obstrutiva com sintomas inespecíficos como dor lombar e complicações como ureterolitíase e pielonefrite, que normalmente aparecem entre a terceira e a quarta décadas de vida, e exige tratamento cirúrgico na maior parte dos casos. Objetivo: Apresentar um caso de ureter retrocava associado a ureterolitíase e uma revisão da literatura a respeito das técnicas cirúrgicas para sua correção. Relato de caso: Os autores apresentam um caso de ureterolitíase e ureter retrocava, diagnosticado por tomografia computadorizada, em um paciente masculino de 43 anos com dor lombar direita, corrigido através de técnica laparoscópica transperitoneal. Conclusão: A correção cirúrgica laparoscópica do ureter retrocava tem se mostrado benéfica em diversos aspectos quando comparada ao acesso aberto e uma abordagem que ainda não havia sido publicada é a correção do ureter retrocava associado a ureterolitíase num mesmo tempo cirúrgico.Palavras chave: Ureter retrocava, Hidronefrose, Ureterolitíase, Anomalia urogenital, LaparoscopiaABSTRACTIntroduction: The retrocaval ureter is a rare congenital malformation which may cause obstructive uropathy with nonspecific symptoms such as low back pain and complications as ureterolithiasis and pyelonephritis, which usually appear between the third and fourth decades of life, and requires surgical treatment in most cases. Objective: To present a case of ureterolithiasis and retrocaval ureter and a review of literature, regarding the different types of access for his surgery. Case Report: The authors present a case of ureterolithiasis and retrocaval ureter diagnosed by computed tomography in a 43-year-old male patient with right lower back pain, corrected using a transperitoneal laparoscopic technique. Conclusion: Laparoscopic surgical correction of the retrocaval ureter has shown to be beneficial in several aspects when compared to open access, and one that has not been previously reported is the one-step resolution of the association with ureterolithiasis.Keywords: Retrocaval ureter, Hydronephrosis, Ureterothiasis, Urogenital abnormalities, Laparoscopy
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5

Inugala, Anusiri. "Neurovesical dysfunction in anorectal malformation." International Surgery Journal 7, no. 12 (November 27, 2020): 4039. http://dx.doi.org/10.18203/2349-2902.isj20205354.

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Background: Anorectal malformations are congenital anomalies characterized by the absence of a normally formed anus. Obstructive uropathy, vesicoureteral reflux neurovesical dysfunction are the leading causes of mortality and morbidity in ARM. Early diagnosis and treatment of NVD prevents renal parenchymal damage.Surgical interventions for the correction of anorectal malformation may also lead to the development of NVD. The incidence of urologic and spinal anomalies associated with ARM and the relationship between the anorectal malformations, spinal abnormalities and voiding dysfunction was studied by means of MRI spine and urodynamic studies. Methods: A prospective, observational study was done over a period of 2 years. All patients with ARM underwent MRI of the spine, ultrasound of abdomen, micturating cystourethrogram and urodynamic study.Results: Forty two patients were included in this study. Out of the 42 patients 17 (40.5%) were female and 25 (59.5%) were male. The ages of the patients ranged from 4 months to 14 years with an average of 32.9 months. 5 patients (12%) had complaints pertaining to neurovesical dysfunction. MRI of the spine revealed abnormalities in 10 patients (23.8%). Urodynamic study was abnormal in 8 patients (19%). Therefore a total of 8 patients (19%) had neurovesical dysfunction in the present study. This included 3 female patients with cloaca and 5 male patients with high anorectal malformations.Conclusions: Neurovesical dysfunction is frequently seen in patients with anorectal malformations. NVD may be due to the spinal abnormalities or due to iatrogenic injuries to the bladder innervations during surgical reconstruction.
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6

Ahoui, Séraphin, Gerard Kpanidja, Alphonse Noudamadjo, Falilatou Agbeille, Hermione Nelly Djima, Ahmed Adegbola, Aristide Dah, Julien Didier Adedemy, and Joseph Agossou. "Epidemiological, Clinical, and Diagnostic Aspects of Urinary Tract Infection in Newborns at the Departmental Teaching Hospital of Borgou-Alibori (DTH-B/A) in Benin." Journal of Renal and Hepatic Disorders 6, no. 1 (April 26, 2022): 41–47. http://dx.doi.org/10.15586/jrenhep.v6i1.127.

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To study epidemiological and diagnostic aspects of urinary tract infection (UTI) in newborns at the Departmental Teaching Hospital of Borgou-Alibori (DTH-B/A). This was a cross-sectional study conducted from April 1, 2019 to September 30, 2019 and concerned all newborns admitted to the neonatal unit of DTH-B/A. According to the National Agency for Health Accreditation and Evaluation (NAHAE)recommendations of 2002, all symptomatic newborns who did not have a visible malformation outside the genitourinary system and whose parents gave their consent were included in the study. The census was exhaustive despite the calculated minimum size of 109 newborns. Urine sedimentation and cytobacteriological examination of urine samples, taken in adhesive bags after local disinfection, demonstrated presence of pathogenic microbes. Sensitivity of detected microbes was studied to different antibiotics. Interpretive reading of antibiograms was established according to the Standards of the French Society of Microbiology (FEMS), edition 2012. If UTI was confirmed, an abdominopelvic ultrasound was performed in search for a malformative uropathy as a contributing factor in newborns. A standardized survey was developed for data collection. The data entered were analyzed using the Epi info software, version 3.5.4. In all, 124 newborns were included in the study. UTI accounted for 8.06% of all neonatal infections and 2.15% of admissions. The average age of onset was 7.8 days, with a gender ratio of 1:1. The main clinical manifestations were jaundice and respiratory distress. Microbes involved were Staphylococcus aureus (6/10), Escherichia coli (2/10), and Klebsiella oxytoca (2/10). The resistance of microbes to antibiotics was generally high. No abnormalities were revealed in the ultrasound. Although neonatal UTI is not a rare infection, bacterial resistance is of concern.
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7

Kone, KalyanaRam. "Arteriovenous malformation causing obstructive uropathy: A different dimension to ovarian vein syndrome." Indian Journal of Urology 30, no. 4 (2014): 448. http://dx.doi.org/10.4103/0970-1591.139580.

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8

Batouche, D. D., L. Sadaoui, M. Sadaoui, and Z. Mentouri-Chenntouf. "Uropathie malformative et son évolution vers l’insuffisance rénale chronique chez l’enfant au CHU d’Oran." Néphrologie & Thérapeutique 9, no. 5 (September 2013): 287. http://dx.doi.org/10.1016/j.nephro.2013.07.209.

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9

Aurore Albane Essomba, Kamsu Zicfried, Jeannette Euranie Kouam, Marguerite Edongue, Sophie Nzotsa, Michèle Natacha Engama, Daniel Armand Kago Tague, and Evelyn Mah. "OEIS complex: A case report and literature review of a rare polymalformative syndrome." World Journal of Advanced Research and Reviews 14, no. 3 (June 30, 2022): 284–90. http://dx.doi.org/10.30574/wjarr.2022.14.3.0551.

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Introduction: The OEIS complex or syndrome is the most severe form of the exstrophy-epispadias complex and is characterized by the existence of an omphalocele, bladder exstrophy, anal imperforation and spina bifida. We report an atypical case of OEIS complex associated with further birth defects admitted to our department. The diagnostic and therapeutic approach to the complex congenital malformations involved are highlighted, as well as difficulties encountered in a limited resource setting. Case Report: This was a neonate referred for the management of a congenital malformation on the first day of life. The baby was born vaginally at 35 weeks of gestation with a birth weight of 2000 g and significant major risk factors for neonatal sepsis. Two antenatal ultrasounds had revealed fetal uropathy. On admission, the clinical exam revealed: a type 1 omphalocele, an anorectal malformation with a recto-urinary fistula and a covered lumbosacral dysraphism. Paraclinical examinations revealed an associated cardiac anomaly. The karyotype analysis was not done due to lack of financial means. Supportive care was given and the neonate underwent surgical reconstruction of birth defects on day 20. Conclusion: The OEIS complex is a rare morbid congenital polymalformative syndrome in neonates. Patients require keen diagnostic enquiry and immediate postnatal multidisciplinary management, with long-term follow-up.
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10

Mulenga, Cuthbert, Dr Osward Bwanga, and Dr Thabo A. Moloi. "Incidental Finding of Posterior Urethral Valve during Routine Antenatal Ultrasound: Diagnostic Imaging Case Report in Botswana." EAS Journal of Radiology and Imaging Technology 4, no. 2 (April 30, 2022): 17–22. http://dx.doi.org/10.36349/easjrit.2022.v04i02.003.

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Medical ultrasound is a particularly useful imaging method used in the diagnosis of urinary fetal anomalies. One such fetal anomaly is the posterior urethral valve (PUV), which is a congenital malformation of the male urethra occurring early in gestation life. PUV is a common cause of obstructive uropathy in males and fetal death during pregnancy. We report from a medical imaging perspective on a rare and high-risk case of a PUV detected during routine antenatal ultrasound imaging in Botswana. The first scan performed at 16 weeks of gestation age was unremarkable. However, subsequent antenatal ultrasound scans at and after 20 weeks demonstrated bilateral hydronephrosis, distended ureters, and a urinary bladder which gradually increased with the gestation age. There was also a corresponding reduction in amniotic fluid and fetal movements. As a result of these complications, the pregnancy was classified as a “high-risk.” At 30 weeks, spontaneous labour occurred, and a fresh still birth male fetus was delivered.
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11

Singh, Neha, Vandana Bansal, and Kaizad R. Damania. "Prenatal diagnosis of congenital megalourethra: a rare anomaly." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (February 27, 2018): 1251. http://dx.doi.org/10.18203/2320-1770.ijrcog20180931.

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Congenital megalourethra is a rare urogenital malformation characterised by pathological elongation and dilatation of penile urethra. It is a form of functional obstructive uropathy which is associated with significant urological and sexual dysfunction secondary to hypoplasia or absence of corpora cavernosa and spongiosa. We report a case of megalourethra in one of the dichorionic diamniotic twin diagnosed prenatally in a young primigravida. Initial ultrasound report suggested two different diagnoses i.e. omphalocoele and gastroschisis. Later, diagnosis of congenital megalourethra was made on detailed ultrasound examination by our fetal medicine consultant. Postnatal gross and ultrasonographic examination confirmed the prenatal diagnosis. In the present case report, we have emphasized proper perineal anatomical ultrasound examination which revealed a megalourethra. Although this anomaly is not lethal in isolation, but it has worse prognosis in presence of other associated structural anomalies. This anomaly also raises the controversy regarding disclosure of sex of foetus in countries like India where sex disclosure is prohibited by law. As this condition typically affects male foetuses and significantly affects sexual function, it may be necessary to reveal fetal sex for appropriate counselling and prognostication to prospective parents. Ethical dilemma arises for practising clinicians while dealing with isolated forms of megalourethra whether to offer termination of pregnancy on the grounds of having significant impact on sexual life due to erectile dysfunction. Anorectal malformation is often associated with megalourethra, although suspected in the present case, can be difficult to identify antenatally prior to 20 weeks (the time limit up to which legal termination can be performed in India). These issues have been highlighted in the present report.
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12

"Cloacal Exstrophy: Documenting a Particular Case in Yaoundé, Cameroon." Journal of Pediatrics & Neonatal Biology 7, no. 1 (May 18, 2022). http://dx.doi.org/10.33140/jpnb.07.01.03.

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Cloacal exstrophy in its most complex form with OEIS syndrome is characterized by the existence of an Omphalocele, Exstrophied bladder, Imperforate anus, and Spina bifida. We report a particular case of Cloacal exstrophy with OEIS complex and further birth defects. The diagnostic and therapeutic approaches, as well as difficulties encountered in a limited resource setting, are highlighted. This was a 1-day old neonate referred for the management of multiple congenital malformations, including antenatal diagnosis of malformative uropathy. On admission, the clinical findings included: a type 1 omphalocele, an anorectal malformation with a recto-urinary fistula and a covered lumbosacral dysraphism. Paraclinical examinations with cardiac and trans fontanelle ultrasound revealed associated cardiac anomaly and findings in favor of lombo-sacral dysraphism. Supportive care was given and surgical reconstruction of birth defects on day 20 was done. In conclusion, cloacal exstrophy is a rare morbid congenital polymalformative syndrome in neonates, especially when presenting with OEIS complex or syndrome. They require prompt diagnosis and immediate postnatal multidisciplinary management, with long-term follow-up for a favorable outcome.
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13

Thabet, Nesrine, Sanda Mrabet, Olfa Mahfoudh, Narjes Ben Aicha, Awatef Azzabi, Wissal Sahtout, Raja Boukadia, et al. "A case of minimal change disease associated to Rubinstein Taybi syndrome." Journal of Clinical Images and Medical Case Reports 3, no. 5 (May 18, 2022). http://dx.doi.org/10.52768/2766-7820/1839.

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Introduction: Focal segmental glomerulosclerosis (FSGS) is the main glomerular nephropathy secondary to malformative uropathies. The latter can be included in the poly malformative syndromes in the pediatric population. However, other glomerular impairments may rarely be associated with some polymalformative syndromes as reported in this rare case of a minimal change disease (MCD) associated with Rubinstein Taybi syndrome (RSTS). Materials and methods: We report a case of pure nephrotic syndrome in a young male patient with RSTS. Case presentation: It is about a 27 year old young patient diagnosed since birth with a Rubinstein Taybi. In 1994, he was hospitalized in pediatrics for acute pyelonephritis. Retrograde urethrocystoscopy (RUC) showed bilateral vesicoureteral reflux (VUR) grade 3 with functional renal asymmetry on scintigraphy. The patient was admitted in nephrology department in 2019 for a pure and intense nephrotic syndrome with abrupt onset. The initial diagnosis retained was glomerular nephropathy particularly a FSGS secondary to his malformative uropathy. Subsequently, in view of the persistence of an intense nephrotic syndrome, the absence of VUR at the RUC, as well as the functional renal symmetry at the scintigraphy, it was decided to perform a renal biopsy. The biopsy showed an optically normal kidney with the presence of some meningial C3 deposits. MCD was then retained. The patient received corticosteroid therapy with a favorable clinical and biological response. Conclusion: Even if reflux nephropathy remains the most frequent cause of glomerulopathy secondary to malformative uropathy, we should not hesitate to perform a renal biopsy in front of an intense nephrotic syndrome with no functional renal impact of the VUR.
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14

Maseki. "A Case of Complete Urorectal Septum Malformation Sequence: Successful Vesicoamniotic Shunting for Obstructive Uropathy." Journal of Clinical Gynecology and Obstetrics, 2014. http://dx.doi.org/10.14740/jcgo283w.

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15

Kiritta, Richard, Georgina Balyorugulu, Maimuna Ahmed, Frank Christopher, Andrea Solnes Miltenburg, and Albert Kihunrwa. "Recurrent obstructive uropathy secondary to pyometrocolpos in an 8-month-old infant: a case report." Journal of Medical Case Reports 14, no. 1 (December 2020). http://dx.doi.org/10.1186/s13256-020-02543-1.

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Abstract Background Pyometrocolpos is accumulation of infected fluid in the uterus and vagina. It is rare in children, mostly seen after menarche as a result of obstructive congenital genital malformation that impairs free drainage of the uterine secretions. In a child, it may present as an acute illness that necessitates urgent and appropriate management and treatment of the underlying cause, which can be a challenge in a resource-limited setting. Case presentation We report a case of pyometrocolpos in an 8-month-old African infant who presented with fever, vomiting, decreased urine output, and abdominal distension of 12 days’ duration. An abdominal examination revealed a subumbilical midline incision scar and a midline lower abdominal mass. She appeared to have presented at the emergency department with similar complaints 2 months earlier and had been diagnosed with pyometra, which was managed by emergency laparotomy for pus drainage, and she was kept on antibiotics. Recovery was established after 10 days of admission, and the patient was discharged to home. Her symptoms reappeared 2 months after the first presentation. Her blood work showed significant leukocytosis with neutrophilia, and abdominal ultrasound depicted bilateral hydronephrosis with hydroureters and a fluid-filled uterus. Examination under anesthesia in the operating theater revealed normal-looking female genitalia with a cribriform hymen, beneath which lied a transverse vaginal septum. Foul-smelling pus was aspirated through the septum, and septectomy was performed to allow 350 ml of pus to drain. A pus sample was sent for culture and sensitivity, and Escherichia coli sensitive to ceftriaxone and gentamicin was isolated. Conclusion Pyometrocolpos is rare in childhood but should be suspected in a girl presenting with a midline lower abdominal mass accompanied with urinary obstructive symptoms associated with fever and gastrointestinal symptoms. Escherichia coli seems to be the most probable offending organism, but pus culture is crucial for antibiotic stewardship in proper management of the infection. Definitive treatment should focus on correcting the obstructive anatomical congenital deformity that caused the obstruction in order to avoid recurrence.
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16

Mazighi, Sara, Hamouche Nabil, Mariam Chettati, Wafaa Fadili, and Inass Laouad. "MO472: Comparison of the Quality of Life and Survival in Children Undergoing Hemodialysis Versus Peritoneal Dialysis: A Comparative Cross-Sectional Study." Nephrology Dialysis Transplantation 37, Supplement_3 (May 2022). http://dx.doi.org/10.1093/ndt/gfac071.003.

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Abstract BACKGROUND AND AIMS A child with end-stage renal disease (ESRD) hopes for a kidney transplant to avoid dialysis. Despite the recent priority rules for assigning transplants to children. Most of them, due to their young age, the time required to prepare for the transplant, and especially the limited availability of grafts, will go on dialysis. The objective of this study is to compare the quality of life and survival of children with ESRD treated by hemodialysis (HD) and those treated by peritoneal dialysis (PD). METHOD All children with end-stage renal disease under the age of 16 who started dialysis treatment between 2018 and 2021 were included, for a total of 72 children. Data were collected from an HRQOL questionnaire (Health Related Quality of Life ESRD Module questionnaire). RESULTS A total of 72 children on ESRD started dialysis between 2018 and 2021. A total of 62 children on hemodialysis (87.5%) versus 10 children on peritoneal dialysis. The mean age in our study was 10 years ± 8 years, with a 58% female predominance. Causal nephropathy was dominated by malformative uropathy in 36% of cases, indeterminate nephropathy in 24% and lupus in 12.5% ​​of cases. Growth retardation was observed in 49 children in our population (79%) (48 in HD versus 1 in PD P < .001). Residual renal function was preserved in 48.6% of our children with a state of normal extracellular hydration (HD 40%, DP 8%). The mean HD and DP hemoglobin level was 8 mg/dL. The initial GFR was 5 with an average urea level at the start of dialysis of 3 g (3 g for HD and 2 g for children on PD). The evolution was marked by the occurrence of complications in PD (6 peritonitis and 2 infections of emergence of KTT) and HD (arteriovenous fistulae hematoma in 10 children, secondary hyperparathyroidism in 65% of children), 10 children are deceased (1 in PD and 9 in HD). Children on PD have a lower co-morbidity and dialysis initiation is more planned. CONCLUSION PD remains the technique of choice in our context to ensure a better quality of life for children.
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