Academic literature on the topic 'Urine analysi'

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Journal articles on the topic "Urine analysi"

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Örd, Lenna, Toomas Marandi, Marit Märk, Leonid Raidjuk, Jelena Kostjuk, Valdas Banys, Karit Krause, and Marika Pikta. "Evaluation of DOAC Dipstick Test for Detecting Direct Oral Anticoagulants in Urine Compared with a Clinically Relevant Plasma Threshold Concentration." Clinical and Applied Thrombosis/Hemostasis 28 (January 2022): 107602962210843. http://dx.doi.org/10.1177/10760296221084307.

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Measuring direct oral anticoagulant (DOAC) concentrations might be necessary in certain clinical situations but is not routinely performed. The DOAC Dipstick is a new rapid test for detecting DOACs in urine. The aim of this study was to evaluate the possible uses and limitations of the DOAC Dipstick and to compare visual analysis and DOASENSE Reader analysis of DOAC Dipstick pads. Plasma and urine samples were collected from 23 patients taking DOACs. DOAC concentrations in plasma and urine were measured by chromogenic substrate assays and in urine also by the DOAC Dipstick. Plasma concentrations were dichotomized at a threshold of ≥30 ng/mL. Patient samples were compared with samples from control individuals not using anticoagulants (n = 10) and with DOASENSE control urines. The Combur-10 test was used to measure parameters that may affect urine color and hence the interpretation of the DOAC Dipstick result. DOAC Dipstick test results were positive in 21/23 patient urine samples at a plasma DOAC concentration of ≥30 ng/mL and in 2/23 patient urine samples at a plasma DOAC concentration of <30 ng/mL. Inter-observer agreement was above 90% for visual analysis of patient urine samples and was 100% for DOASENSE Reader analysis of patient urines and for analysis of control group urines and DOASENSE control urines. Abnormalities in urine color detected by the Combur-10 test did not affect the DOAC Dipstick results. DOAC Dipstick detects DOACs in urine at a plasma threshold of ≥30 ng/mL. Positive DOAC Dipstick results should be confirmed by measuring DOAC plasma concentration.
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Clark, D. R., and T. M. Hajar. "Detection and confirmation of cocaine use by chromatographic analysis for methylecgonine in urine." Clinical Chemistry 33, no. 1 (January 1, 1987): 118–19. http://dx.doi.org/10.1093/clinchem/33.1.118.

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Abstract Methylecgonine is a common metabolite of cocaine in man. We prepared methylecgonine and developed thin-layer chromatographic and gas-chromatographic methods for its detection in urine. Seventy urine specimens from our drug screening laboratory were tested by our method and by EMIT. Both methods were positive for 26 urines, and both were negative for 42 urines. The other two urines were shown to contain cocaine by GC/MS, and no detectable metabolites. We thus demonstrated that detection of methylecgonine and cocaine is as sensitive a test for cocaine use as EMIT.
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Juhariah, Jujuk, and Margaretha Praba Aulia. "Analisis Pertumbuhan Tanaman Cabai Keriting dalam Polybag menggunakan Pupuk Fermentasi Urin Sapi." METANA 17, no. 2 (November 16, 2021): 49–54. http://dx.doi.org/10.14710/metana.v17i2.42565.

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Tahun 2020 merupakan tahun yang cukup sulit bagi masyarakat Indonesia. Adanya virus corona jenis baru memaksa masyarakat untuk beradaptasi dengan kebiasaan baru. Salah satu masalah terbesar yang dihadapi adalah dengan adanya kebijakan lockdown yang menyebabkan sulitnya distribusi bahan pangan. Oleh sebab itu edukasi masyarakat untuk memanfaatkan lahan pekarangan secara organik dengan mengoptimalkan sumber daya yang ada disekitar pekarangan rumah perlu dilakukan. Tujuan penelitian ini adalah untuk mengetahui respon tanaman cabai keriting dengan menggunakan pupuk fermentasi urin sapi. Penelitian dilakukan dengan cara memberikan perlakuan variasi pemupukan dengan mencampur urin sapi dan EM4 (perlakuan A); urin sapi, EM4, dan batang pohon pisang (perlakuan B); urin sapi, EM4, dan sabut kelapa (perlakuan C); dan urin sapi, EM4, dan akar kacang tanah (perlakuan D). Parameter yang diamati dalam penelitian ini adalah tinggi tanaman, jumlah daun, diameter batang, dan bobot biomassa kering tanaman. Perlakuan penambahan sabut kelapa pada fermentasi urin sapi memberikan pengaruh yang nyata pada parameter tinggi tanaman. Sedangkan penambahan akar kacang tanah pada fermentasi pupuk urin sapi meningkatkan bobot biomassa kering tanaman secara signifikan. Penambahan batang pohon pisang pada fermentasi urin sapi secara nyata memberikan pengaruh terhadap diameter batang tanaman cabai keriting. Akan tetapi, jumlah daun tidak menunjukkan perbedaan yang signifikan dari semua jenis pemupukan. The year 2020 is quite a difficult year for the people of Indonesia. The existence of a new coronavirus type forces people to adapt to new habits. One of the biggest problems faced is the lockdown policy which makes it difficult for food distribution. Therefore, it is necessary to educate the public to utilize the yard organically by optimizing the existing resources around the yard of the house. This study aimed to determine the response of curly chili plants using cow urine fermentation fertilizer. The research was conducted by giving various fertilization treatments by mixing cow urine and EM4 (treatment A); cow urine, EM4, and banana tree trunks (treatment B); cow urine, EM4, and coconut husk (treatment C); and cow urine, EM4, and groundnut root (treatment D). Parameters observed in this study were plant height, number of leaves, stem diameter, and dry biomass weight of the plant. The addition of coconut fiber in cow urine fermentation has a significant effect on plant height parameters. Meanwhile, the addition of groundnut roots to fermented cow urine fertilizer increased the dry biomass weight of the plant significantly. The addition of banana tree trunks to cow urine fermentation significantly affected the stem diameter of curly chili plants. However, the number of leaves did not show a significant difference between all types of fertilization.
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Regeniter, Axel, André Scholer, and Werner H. Siede. "Die quantitative Analyse von Markerproteinen im Urin Quantitative analysis of marker proteins in urine." LaboratoriumsMedizin 29, no. 5 (January 1, 2005): 309–16. http://dx.doi.org/10.1515/jlm.2005.042.

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van Kuilenburg, André B. P., Henk van Lenthe, Monika Löffler, and Albert H. van Gennip. "Analysis of Pyrimidine Synthesis “de Novo” Intermediates in Urine and Dried Urine Filter- Paper Strips with HPLC–Electrospray Tandem Mass Spectrometry." Clinical Chemistry 50, no. 11 (November 1, 2004): 2117–24. http://dx.doi.org/10.1373/clinchem.2004.038869.

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Abstract Background: The concentrations of the pyrimidine “de novo” metabolites and their degradation products in urine are useful indicators for the diagnosis of an inborn error of the pyrimidine de novo pathway or a urea-cycle defect. Until now, no procedure was available that allowed the analysis of all of these metabolites in a single analytical run. We describe a rapid, specific method to measure these metabolites by HPLC–tandem mass spectrometry. Methods: Urine or urine-soaked filter-paper strips were used to measure N-carbamyl-aspartate, dihydroorotate, orotate, orotidine, uridine, and uracil. Reversed-phase HPLC was combined with electrospray ionization tandem mass spectrometry, and detection was performed by multiple-reaction monitoring. Stable-isotope-labeled reference compounds were used as internal standards. Results: All pyrimidine de novo metabolites and their degradation products were measured within a single analytical run of 14 min with lower limits of detection of 0.4–3 μmol/L. The intra- and interassay variation for urine with added compounds was 1.2–5% for urines and 2–9% for filter-paper extracts of the urines. Recoveries of the added metabolites were 97–106% for urine samples and 97–115% for filter-paper extracts of the urines. Analysis of urine samples from patients with a urea-cycle defect or pyrimidine degradation defect showed an aberrant metabolic profile when compared with controls. Conclusion: HPLC with electrospray ionization tandem mass spectrometry allows rapid testing for disorders affecting the pyrimidine de novo pathway. The use of filter-paper strips could facilitate collection, transport, and storage of urine samples.
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Starcher, Barry, and Marti Scott. "Fractionation of Urine to Allow Desmosine Analysis by Radioimmunoassay." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 29, no. 1 (January 1992): 72–78. http://dx.doi.org/10.1177/000456329202900111.

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The present study was designed to re-evaluate the radioimmunoassay for desmosine in urine, which is currently used as a measure of elastin metabolism. Using ion exchange chromatography, gel filtration and affinity chromatography it was shown that at least five other compounds in hydrolysates of human urine competed for desmosine in the RIA. Fractionating the urine prior to hydrolysis with acetone removed one of the major contaminants. The other contaminants could subsequently be removed by extracting the urine hydrolysate with a mixture of chloroform/ethanol (60:40). Samples from nine normal adult urines showed that an average of 45% of the RIA competing material in unfractionated urine was not desmosine. The final extracted residue retained all of the desmosine and only 16% of the original solids. The average adult urine contains approximately 50 pmol desmosine/mg creatinine, reflecting a daily turnover of between 3 and 4 mg of elastin per day.
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Peelen, G. O., J. G. de Jong, and R. A. Wevers. "HPLC analysis of oligosaccharides in urine from oligosaccharidosis patients." Clinical Chemistry 40, no. 6 (June 1, 1994): 914–21. http://dx.doi.org/10.1093/clinchem/40.6.914.

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Abstract Analysis of urinary oligosaccharides by thin-layer chromatography (TLC) is used as screening procedure for 10 different lysosomal diseases. We tested the usefulness of HPLC in screening, using a CarboPac PA1 column (Dionex), pulsed amperometric detection (PAD), and post-column derivatization (PCD). Patterns from six types of oligosaccharidoses were compared with normal urinary patterns and with the TLC patterns. PAD appeared to be nonspecific and therefore is applicable only to desalted urine samples. PCD was more specific and applicable to nondesalted urine samples, albeit with a lower resolving power. Peaks in urines from oligosaccharidoses patients were identified on the basis of retention times of commercially available oligosaccharides or TLC bands after isolation and HPLC of the corresponding oligosaccharides. Abnormal oligosaccharide peaks were seen in urines from patients with alpha-mannosidosis, GM1-gangliosidosis (juvenile), GM2-gangliosidosis (Sandhoff disease), Pompe disease, and beta-mannosidosis. HPLC detected no abnormal oligosaccharides in urine from patients with fucosidosis. Although TLC is a simple and reliable screening procedure for detecting classical lysosomal diseases with oligosaccharide excretion, HPLC, by its higher resolution and possibility of quantification, can more generally be used for recognition of abnormal oligosaccharides or detection of increased excretion or content for known oligosaccharides in urine, other body fluids, and cells.
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Hamid Saad Mohmoud1, Marai. "Dipstick urine analysis screening among asymptomatic dogs of k9 units." Iraqi Journal of Veterinary Medicine 42, no. 1 (2018): 61–64. http://dx.doi.org/10.30539/011.

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WU, Jun, Chao Yan ZHOU, Ming Keong WONG, Hian Kee LEE, Hua CHI, and Choon Nan ONG. "Speciation of Aluminum in Urine." Analytical Sciences 12, no. 4 (1996): 641–45. http://dx.doi.org/10.2116/analsci.12.641.

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Kustyorini, Tri Ida Wahyu, and Permata Ika Hidayati. "Pengaruh perendaman benih pada berbagai jenis larutan urin terhadap daya tumbuh kecambah kaliandra (calliandra calothyrsus)." Jurnal Sains Peternakan 6, no. 01 (June 29, 2018): 47–52. http://dx.doi.org/10.21067/jsp.v6i01.2815.

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Abstrak Penelitian ini bertujuan untuk mengetahui hasil pengaruh perendaman benih pada berbagai jenis larutan urin terhadap daya tumbuh kecambah kaliandra (Calliandra calothyrsus). Materi yang digunakan dalam penelitian ini adalah benih kaliandra sebanyak 100 gr, urin sapi, kambing dan domba sebanyak @1 liter. Metode yang digunakan dalam penelitian ini adalah eksperimental lapang berdasarkan Rancangan Acak Lengkap (RAL) yang terdiri atas 5 perlakuan dan 3 ulangan. Perlakuan penelitian terdiri dari P0 (perlakuan kontrol/tanpa perendaman), P1 (perendaman pada air) dan perlakuan eksperimental dengan perendaman pada berbagai jenis urin dengan konsentrasi 10%, yakni, P2 (larutan urin sapi), P3(larutan urin kambing) dan P4 (larutan urin domba). Variabel yang diamati dalam penelitian ini yaitu daya tumbuh kecambah kaliandra yang meliputi persentase perkecambahan, tinggi bibit, persentase benih mati, dan persentase kecambah normal. Data yang diperoleh dianalisis dengan menggunakan analisis sidik ragam anova tunggal dengan bantuan aplikasi SPSS for Windows,apabila terdapat pengaruh maka dilanjutkan dengan uji. Perendaman pada urin sapi memberikan nilai terbaik pada persentase kecambah (88,33%), tinggi bibit (5,67±0,57)cm, persentase benih mati terendah (11,67±3,51%), dan persentase kecambah normal (91,67±1,52%). Kesimpulan dari hasil penelitian yaitu perendaman benih pada urin sapi memberikan pengaruh terbaik terhadap daya tumbuh kecambah kaliandara (Calliandra calothyrsus). Abstract This study aims to determine the effect of seed immersion on various types of urine solution on the growth of Calliandra calothyrsus. The material used in this study was 100 grams of calliandra seed, cow urine, goat urine and sheep urine. The method used in this study was a field experiment based on a Completely Randomized Design (CRD) consisting of 5 treatments and 3 replications. The treatment consisted of P0 (control / no soaking treatment), P1 (immersion in water) and experimental treatment with soaking in various types of urine with a concentration of 10%, namely, P2 (cow urine solution), P3 (goat urine solution) and P4 (sheep urine solution). The variables observed in this study were the growth of kaliandra sprouts which included germination percentage, seed height, percentage of dead seeds, and the percentage of normal sprouts. The data obtained were analyzed using a single ANOVA variance analysis with the help of the SPSS for Windows application, if there was an influence then proceed with the test. Immersion in cow urine gave the best value in the percentage of sprouts (88.33%), seedling height (5.67 ± 0.57) cm, the lowest percentage of dead seeds (11.67 ± 3.51%), and the percentage of normal sprouts ( 91.67 ± 1.52%). The conclusion of the research results is that the immersion of seeds in cow urine gives the best effect on the power of kaliandara sprouts (Calliandra calothyrsus).
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Dissertations / Theses on the topic "Urine analysi"

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PADOAN, ANDREA. "Statistical methods for mass spectrometry data analysis and identification of prostaste cancer biomarkers." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50248.

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BACKGROUND Prostate Cancer (PCa) is the most common cancer among males in Europe. Patients developing early PCa sometimes refer non-specific symptoms, namely lower urinary tract symptoms (LUTS), and they usually undergo medical investigations based on Prostate Specific Antigen (PSA) and Digital Rectal Examination (DRE). Suspicious results of one or both testings are prerequisite to Prostate Biopsy. However, due to PSA low sensitivity/specificity in predicting positive prostate biopsy, the identification of new PCa biomarkers is actually a real need. MALDI-TOF/MS protein profiling could be a valuable technology for biomarkers identification. However, up to now its use is laden with lack of reproducibility that confounds scientific inferences and limits its broader use. AIMS Goal of this study is to analyze urine collected after prostatic massage in patients referring LUTS, to identify candidate biomarker for PCa, by using MALDI-TOF/MS. We considered important aspects of MALDI-TOF/MS label-free proteomic profiling, in order to assess features reproducibility and to propose appropriate strategy to handle both measurement error and limit of detection (LOD) problems. The study results should aid in reducing the number of worthless first-biopsied and assist Urologists on differential diagnosis of PCa. METHODS In a cross-sectional study, we collected urine obtained after DRE from 205 patients that referred LUTS to consultants at the Urological Unit at University of Padova. All patients undergone to prostate biopsy for suspicious PCa. Urines were dialyzed and analyzed by MALDI-TOF/MS in reflectron mode. For the MALDI-TOF/MS reproducibility evaluation, we analyzed a urine pooled from 10 reference samples, spiked with 12.58 pmol of a 1589.9 m/z internal standard (IS) peptide. For the inter-run variability assessment, 14 aliquots were dialyzed by MALDI-TOF/MS. For the intra-run study, an aliquot was divided into 26 separate sub-aliquots and analyzed by MALDI- TOF/MS. To estimate the signal detection limit (sLOD), serial dilution up to 1/256 of a urine pool were analyzed in triplicate. We evaluated the sLOD and adjusted the data appropriately to reduce its variability. We investigated six data normalization approaches - the mean, median, internal standard, relative intensity, total ion current and linear rescaling normalization. Between-spectrum and the overall spectra variability were evaluated by the coefficient of variation (CV). An optimized signal detection strategy was also evaluated to overcome peak detection algorithms errors. Measurement errors and with-in subject variances were evaluated by an external dataset, made of urine repeatedly collected from 20 reference subjects. Intra class correlation coefficient (ICC), Regression Calibration (RCAL) and SIMEX analyses were used to estimate unbiased logistic regression coefficients relating MALDI-TOF/MS features with Patients biopsy outcome. Monte Carlo simulations were used to estimate influence of different LOD adjustment methods on ICC and RCAL. RESULTS Initially, we evaluated the intra- and inter-run on data obtained from automatic peak detection. Normalization methods performed almost similarly in both studies, except IS, which resulted in an increased CV. Calculated sLOD varied with spectra m/z. After sLOD adjustment, raw and normalized data showed a reduction in CVs, while median and mean normalizations performed better, especially in the intra-assay study. However, by optimizing the peak signal detection, the overall features variability drastically decreased. Median normalization with sLOD correction remained the preferable choice for further analyses. Evaluating the external dataset, we found that most of the MALDI-TOF/MS variability is intrinsic to the biological matrix. By using substitution of below LOD values by LOD/2, simulation studies showed that ICC estimations were poorly affected by LOD, when measurement error σ is less that 0.36 and values below LOD are less that 50%. Comparing results from naïve logistic regression, RCAL and SIMEX, measurement error appeared to cause a "bias toward the null". However, SIMEX estimations seemed to correct for a smaller amount of bias than RCAL. Overall, we found eight MALDI-TOF/MS features associated with positive biopsy results. CONCLUSION Findings from the reproducibility study showed that the major contributing factor for MALDI-TOF/MS profiling variability is the peak detection process. So, a new algorithm suited for MALDI-TOF reflectron mode is desirable for its applications in profiling studies. However, normalization strategies aid in increasing MALDI-TOF/MS label-free data reproducibility, especially with sLOD correction. Despite urine does not seem to be a promising biological fluid for proteomic biomarker discovers, RCAL and SIMEX appeared valuable approaches to obtain regression coefficients adjusted for biological and instrumental errors on MALDI-TOF/MS features.
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Rocha, Diogo Librandi da. "Desenvolvimento de procedimento analítico em fluxo com multicomutação para a determinação espectofotométrica de ácido úrico em urina." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-05102009-105307/.

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A mecanização de procedimentos analíticos em análises clínicas traz vantagens tais como minimização de erros sistemáticos e do tempo das análises. Sistemas de análises em fluxo com multicomutação apresentam grandes potencialidades nesse sentido, atendendo às necessidades da mecanização de procedimentos analíticos de maneira versátil e robusta. Estes sistemas permitem minimizar o consumo de reagentes e a geração de resíduos, devido ao gerenciamento preciso de pequenos volumes de soluções por dispositivos controlados eletronicamente, tais como microbombas solenoide. O fluxo pulsado proporcionado pelas microbombas e a estratégia da amostragem binária melhoram a mistura entre amostra e reagentes. O ácido úrico é o principal produto final do metabolismo de purinas. A determinação deste analito em amostras de urina apresenta importância clínica, uma vez que sua concentração pode auxiliar no diagnóstico de disfunções no organismo humano, como a gota e o mau funcionamento dos rins. Um procedimento analítico empregando sistema de análises em fluxo com microbombas solenoide foi desenvolvido para a determinação de ácido úrico em amostras de urina. Os íons Cu(II) são reduzidos pelo ácido úrico a íons Cu(I), que podem ser quantificados por espectrofotometria na presença do ácido 4,4\'-dicarboxi-2,2\'- biquinolínico (BQA). Resposta linear foi observada entre 10 e 100 µmol L-1 de ácido úrico, sendo a curva analítica representada pela equação A=(0,0063±0,0002)CAU + (0,0285±0,0040), r = 0,999, em que CAU é a concentração de ácido úrico em µmol L-1. O limite de detecção foi estimado em 3,0 µmol L-1 (99,7% de nível de confiança; n = 20). O coeficiente de variação foi estimado em 1,2% com 20 medidas de uma solução de ácido úrico 75 µmol L-1 e a frequência de amostragem foi de 150 h-1. As principais espécies concomitantes presentes na urina não interferem na determinação de ácido úrico em concentrações até 5 vezes maiores que as usualmente encontradas. Recuperações entre 91 e 112% foram estimadas e os resultados das análises de 4 amostras de urina concordaram com os obtidos pelo procedimento enzimático para a determinação de ácido úrico (95% de nível de confiança). O alto grau de diluição da amostra necessário (100 vezes) minimiza o volume de amostra utilizado e os efeitos de matriz. Uma simples reconfiguração do sistema e a reotimização das frações volumétricas permitiram que a amostra fosse diluída em linha por reamostragem na zona dispersa. Resposta linear foi observada até 5,0 mmol L-1 de ácido úrico, sendo a curva analítica obtida representada pela equação A=(0,105±0,001) CAU + (0,023±0,003), r=0,999, em que CAU é a concentração de ácido úrico em mmol L-1. O coeficiente de variação, o limite de detecção e a frequência de amostragem foram estimados em 1,0%, 0,2 mmol L-1 e 95 h-1, respectivamente. Os resultados da análise de 3 amostras de urina concordaram com os obtidos pelo procedimento enzimático, com nível de confiança de 95%
Mechanization of analytical procedures in clinical analysis brings advantages such as minimization of systematic errors and analysis time. Multicommuted flow systems attain the requirements to mechanization of analytical procedures in a versatile and robust way, minimizing reagent consumption and waste generation, due to the low solution volumes handled by electronically controlled devices, such as solenoid micro-pumps. The pulsed flow characteristic of the micro-pumps and the binary sampling approach improve sample and reagent mixing. Uric acid is the main end product of purine metabolism and its determination in urine shows clinical importance, because its concentration can be related to human organism dysfunctions, such as gout and renal disorders. An analytical procedure employing a flow system with solenoid micro-pumps was developed, aiming the determination of uric acid in urine samples. Cu(II) ions are reduced by uric acid to Cu(I) ions that can be quantified by spectrophotometry in the presence of 2,2´-biquinoline 4,4´-dicarboxylic acid (BCA). Linear analytical response was observed between 10 and 100 µmol L-1 uric acid and the analytical curve corresponds to the equation A=(0.0063±0.0002) CUA + (0.0285±0.0040), r = 0.999, in which CUA is the uric acid concentration in µmol L-1. The detection limit was estimated as 3.0 µmol L-1 (99.7% confidence level; n = 20). The coefficient of variation was estimated in 1.2% with 20 replicates of a 75 µmol L-1 uric acid solution and sampling rate of 150 h-1 was achieved. The main concomitant species does not interfere in uric acid determination in concentrations up to 5-fold higher than that usually found in urine samples. Recoveries from 91 to 112% were estimated and the results for 4 urine samples agreed with those obtained by the commercially available enzymatic kit for determination of uric acid (95% confidence level). The 100-fold sample dilution minimizes sample consumption and matrix effects. A simple system reconfiguration and a re-optimization of volumetric fractions attained on-line sample dilution by zone sampling. Linear response was observed up to 5.0 mmol L-1 uric acid and the analytical curve corresponds to the equation A=(0.105±0.001) CUA\' + (0.023±0.003), r = 0.999, in which CUA\' is the uric acid concentration in mmol L-1. The coefficient of variation, detection limit and sampling frequency were estimated as 1.0%, 0.2 mmol L-1 and 95 h-1, respectively. The results of the analysis of 3 urine samples also agreed with those obtained with the enzymatic procedure at the 95% confidence level
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Lough, Patricia Schechter. "Use of urine samples for ethanol analysis." CSUSB ScholarWorks, 1989. https://scholarworks.lib.csusb.edu/etd-project/446.

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Paquin, Olivier. "La microalbuminurie chez le sujet âgé." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2M113.

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Jansson, Emelie. "Gaskromatografisk metod för analys av GHB i urin." Thesis, Department of Physics, Chemistry and Biology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-19651.

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En metod för detektering och kvantifiering av gamma-hydroxysmörsyra (GHB) i urin med gaskromatografi (GC) är framtagen på Sahlgrenska universitetssjukhuset. Metoden är relativt unik då den inte kräver upparbetning i form av derivatisering, indunstning eller extraktion. Urinen surgörs med koncentrerad saltsyra och internstandard, gamma-valerolakton, tillsätts. GHB övergår då till laktonformen, gamma-butyrolakton (GBL). Därefter injiceras provet direkt på en GC-FID med en kapillärkolonn för glykoler och alkoholer. Detektion ner till 100 μmol/L är möjligt med en variationskoefficient mellan 6 och 12 %. Provsvar erhålls efter 6,5 minuter. Metoden är dock inte fullständig då en del frågetecken kvarstår. Bland annat bör det undersökas om andra föreningar, som kan förekomma i urin, kan eluera samtidigt som GHB. Om ja så bör vidare analyser genomföras för att separera GHB och den andra föreningen. Metoden kan däremot användas i nuläget som en screeninganalys för att snabbt få ett svar på om GHB finns närvarande eller inte. Verifiering kan sedan ske med GC-MS.


A method for determination and quantification of gamma-hydroxyburyric acid (GHB) in urine samples is developed at Sahlgrenska universitetssjukhus. No time consuming procedures as derivatization and exctration is required, which makes the method fairly unique. Hydrochloric acid and internal standard, gamma-valerolakton, is added to the urine sample before the sample is injected to a gas chromatograph with a flame ionization detector and a column for glycols and alcohols. The hydrochloric acid makes the GHB convert into gamma-butyrolactone (GBL) which is easier to separate in the gas chromatograph. Limit of detection was found to be 100 μmol/L and test result is received after 6,5 minutes. There are still some question marks around the method, for example, there is a possibility that another substance elute at the same time as GHB. More tests are required to determine whether or not it is so. For now the method can be used as a screening analysis to hastily detect GHB presence. Verification can be done with GC-MS.

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Cooper, Mark Thomas. "A chromatographic method for detecting phenolic metabolites of carbosulfan in urine." Thesis, Queensland University of Technology, 1989. https://eprints.qut.edu.au/35977/1/35977_Cooper_1989.pdf.

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The inability of the conventional blood cholinesterase test to reliably detect carbamate pesticide poisoning in humans prompted the investigation of an alternative surveillance method. Rapid, micro-scale sample treatment procedures were developed to extract the phenolic metabolites of carbosulfan from urine, convert these compounds to their dinitrophenyl ether derivatives and determine their concentrations quantitatively by nitrogen selective gas-liquid chromatography. This method was capable of detecting micro-gram levels of metabolites and performed to an accuracy of<+/ 10% and precision of< 6% RSD. In vivo experiments we re undertaken in which carbosul fan was administered to laboratory rats and the effects of dosage and sampling time on the level of phenolic metabolites in urine were examined. These results provide guidelines for human exposure however absolute confidence in these thresholds will only occur when the data base of human experience is collected and correlated to metabolite levels in urine. Urine samples were drawn and analyzed from potentially exposed personnel handling carbosulfan and in all cases no phenolic metabolites were detected.
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Chen, Hui-Chuen. "The urinary excretion of mercapturic acids in free-living adult males." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-12052009-020010/.

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Allen, Robert Douglas III. "Development of an assay for the detection of cytomegalovirus in urine." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/25410.

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Hoang, Tiffany Truc. "Speciation and identification of low molecular weight organoselenium metabolites in human urine." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/30671.

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Silva, Júnior Jarbas Miguel da. "Excreção urinária de derivados de purinas e de compostos nitrogenados de zebuínos em pastejo." Universidade Federal de Viçosa, 2014. http://locus.ufv.br/handle/123456789/5825.

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This study aimed evaluating the excretion of purine derivatives and nitrogen compounds in zebu cattle grazing, on different days and times within days. The experiment was conducted in the cattle department of the Federal University of Viçosa / MG, using five Nelore heifers with an average body weight of 300 ± 15 kg and 20 months of age, in 5x5 Latin square design. The experimental treatments were defined to represent those commonly used in the dry season, as follows: control (mineral salt), concentrated with 20.31% crude protein (CP) on dry matter (DM) being offered (OF) level of 0.5 to 1% of body weight fasted (BWF) OF5 and OF10, respectively; and two concentrated self- regulating (SR) consumption, containing 69.38% CP on a DM basis (20% urea and 20% salt) offered ad libitun (SR70) and other concentrate containing 39.73% CP based on MS being offered ad libitum (SR40). The experimental periods was 18 days, with one day to perform 14 hours of fasting for weighing and adjustment of the quantities supplied, 12 days for adaptation to the experimental diets and five for total collection of urine and stool sample at the times of 0h00a.m. to 4h00a.m, 4h00a.m. to 8:00a.m., 8:00a.m. to 12:00p.m., 12:00p.m. to 4:00p.m., 4:00p.m. to 8:00p.m. and 20:00p.m. to 0:00a.m. For total collection of urine was used probe Folley number 26, coupled to polyethylene hose leading to a urine collection bag for urine closed system, which was emptied every two hours in the range of 8:00a.m. to 8:00p.m., and every four hours in the range from 8:00p.m. to 8:00a.m. and subsequently homogenized and cooled. The collected urine sampling was performed every four hours, measuring the volume, and withdrawing one sample were diluted in H 2 SO 4 at 0,036N and another don't diluted. To estimate fecal output, used the titanium dioxide, provided the total daily amount of 15g, between 9 th and 18 th day of each period. To estimate the intake of pasture, used the indigestible neutral detergent fiber (iNDF) as internal indicator. Was performed by collecting pasture technique for determining the square potentially digestible dry matter (PDDM) on the third day of each experimental period, and on days 14 th and 18 th was held grazing simulation to estimate the consumption of constituents of diets. In urine samples the concentrations of creatinine, total nitrogen, urea, uric acid and allantoin. For statistical analysis we used the statistical program SAS Proc Mixed. Dry matter intake 10was higher (P<0.05) for the treatment OF10 compared to SR70, SR40 and control treatments but was not different (P>0.05) treatment OF5. The CP intake increased by supplementation (P<0.05), which caused no effect on DM intake from pasture. Excretions of creatinine did not change treatment, day and sampling period (P>0.05) and had a mean of 23.03 ± 0.30 mg / kgPC. Urinary relations of allantoin (Al) and uric acid (UA) with creatinine were not affected (P>0.05) by treatments, collection days and times of collection. The total nitrogen relations:creatinine and urea nitrogen:creatinine in urine showed interaction (P<0.05) between treatment and sampling period. The relationship between urea nitrogen:total nitrogen was influenced (P<0.05) only at time of collection. The nitrogen balance (NB) in g/day did not differ between treatments OF10, SR70 and SR40, however these had higher retention of N (P<0.05) than treatments OF5 and control, which were not different. The NB, in g/ging, showed differences (P<0.05) between treatments with concentrated, which did not differ (P> 0.05), and control treatment, with the lowest NB. The production of microbial N was not affected (P>0.05) by treatments. The microbial efficiency gPBmic/kgMOD and gPBmic/kgNDT was affected (P<0.05) by supplementation, being higher (P<0.05) for OF5, OF10 and SR70 treatments, which did not differ. The control and OF5, treatments had the lowest values were similar. The lack of effect of day and the collection period on allantoin and uric acid compared with creatinine has wide practical application, enabling use spot urine sample to calculate the excretion of purine derivatives at any time of day or night, and consequently the microbial production. Depending on the variations observed for total nitrogen and urea nitrogen relations with creatinine over 24 hours is not recommended the use of a single spot urine sample for determination of these nitrogen compounds.
O presente trabalho foi desenvolvido com os objetivos de avaliar a excreção dos derivados de purinas e de compostos nitrogenados em zebuínos em pastejo, em diferentes dias e períodos dentro de dias. O experimento foi conduzido no setor de gado de corte da Universidade Federal de Viçosa/MG, utilizando-se cinco novilhas Nelore com peso corporal médio de 300 ± 15kg e 20 meses de idade, distribuídas em quadrado latino 5x5. Os tratamentos experimentais foram definidos para representar aqueles normalmente utilizados na época seca do ano, sendo eles: controle (sal mineral), concentrado com 20,31% de proteína bruta (PB) com base na matéria seca (MS) sendo oferecido (OF) em nível de 0,5 e 1% do peso corporal em jejum (PCJ), OF5 e OF10, respectivamente; e dois concentrados autorreguladores (AR) de consumo, um contendo 69,38% PB com base na MS (20% de ureia e 20% de sal) ofertado ad libitun (AR70) e outro concentrado contendo 39,73% PB com base na MS sendo ofertado ad libitum (AR40). Os períodos experimentais possuíram 18 dias, sendo o dia um para realização de jejum de 14 horas para pesagem e ajuste das quantidades fornecidas, 12 para adaptação dos animais às dietas experimentais e cinco para a coleta total de urina e amostral de fezes, nos horários das 0h00 às 4h00, 4h00 às 8h00, 8h00 às 12h00, 12h00 às 16h00, 16h00 às 20h00 e 20h00 às 24h00. Para a coleta total de urina utilizou-se sonda de Folley no26, acoplada a mangueira de polietileno que conduziu a urina até uma bolsa coletora de urina por sistema fechado, que foi esvaziada a cada duas horas no intervalo das 8h00 às 20h00, e a cada quatro horas no intervalo das 20h00 às 8h00, sendo posteriormente homogeneizadas e resfriadas. A amostragem da urina coletada foi realizada a cada 4 horas, medindo-se o volume e retirando-se duas amostras, uma diluída com solução H2SO4 0,036N e não diluida. Para determinação da excreção fecal, utilizou-se o dioxido de titânio, fornecido na quantidade total diária de 15g, entre os dias 9 e 18 de cada período. Para estimativa do consumo de pasto, utilizou-se a fibra indigestível em detergente neutro (FDNi), como indicador interno. Realizou-se coleta de pasto pela técnica do quadrado para determinação da matéria seca potencialmente digestível (MSpd) no terceiro dia de cada período experimental, e nos dias 14o e 18o realizou-se simulação de pastejo para estimar os consumos dos constituintes das dietas. Nas amostras de urina foram determinadas as concentrações de creatinina, nitrogênio total, ureia, acido úrico e alantoína. Para análise estatística utilizou-se o programa estatístico Proc Mixed do SAS. O consumo de MS foi superior (P<0,05) para o tratamento OF10 em relação aos tratamentos AR70, AR40 e controle, mas não diferiu (P>0,05) do tratamento OF5. O consumo de PB aumentou com a suplementação (P<0,05), que não causou efeito sobre o consumo de MS do pasto. As excreções de creatinina não sofreram efeito de tratamento, dia e período de coleta (P>0,05) e apresentaram média de 23,03 ± 0,30 mg/kgPC. As relações urinárias da alantoína (Al) e do ácido úrico (AU) com a creatinina não foram influenciadas (P>0,05) pelos tratamentos, dias de coleta e horários de coleta. As relações nitrogênio total:creatinina e nitrogênio ureico:creatinina na urina apresentaram interação (P<0,05) entre tratamento e período de coleta. A relação entre nitrogênio ureico:nitrogênio total foi influenciada (P<0,05) apenas pelo horário de coleta. O balanço de compostos nitrogenados (BN), em g/dia, não diferiu entre os tratamentos OF10, AR70 e AR40, contudo esses apresentaram maiores retenções de N (P<0,05) que os tratamentos OF5 e controle, que não foram diferentes. O BN, em g/ging, apresentou diferença (P<0,05) entre os tratamentos com concentrado, que não diferiram entre si (P>0,05), e tratamento controle, que apresentou o menor BN. A produção de compostos nitrogenados microbianos não foi alterada (P>0,05) pelos tratamentos. A eficiência microbiana, em gPBmic/kgMOD e gPBmic/kgNDT foi afetada (P<0,05) pela suplementação, sendo maior (P<0,05) para os tratamentos OF5, OF10 e AR70, que não diferiram entre si. Os tratamentos controle e OF5, apresentaram os menores valores e foram semelhantes entre si. A ausência de efeito de dia e do período de coleta sobre a relação alantoína e ácido úrico com a creatinina tem grande aplicação prática, possibilitando utilizar a amostra spot de urina para calcular a excreção de derivados de purinas em qualquer horário do dia ou da noite, e consequentemente a produção microbiana. Em função das variações observadas para as relações nitrogênio ureico e nitrogênio total com a creatinina ao longo do período de 24 horas não se recomenda o uso de uma única amostra spot de urina para determinação destes compostos nitrogenados.
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Books on the topic "Urine analysi"

1

Fundamentals of urine & body fluid analysis. 3rd ed. St. Louis, Mo: Elsevier/Saunders, 2013.

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), Dranow Merilee (Tr, ed. The Golden Fountain: Complete Guide to Urine Therapy. Bath: Gateway Books., 1998.

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G, Newall R., and Howell R, eds. Clinical urinalysis: The principles and practice of urine testing in the hospital and community. Stoke Poges: Ames Division, Miles, 1990.

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Fundamentals of urine and body fluid analysis. Philadelphia: Saunders, 1994.

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Associations, American Trucking, ed. The Correct collection of urine samples. Alexandria, VA (2200 Mill Rd., Alexandria 22314-4677): American Trucking Associations, 1989.

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The urinary proteome: Methods and protocols. New York, NY: Humana Press, 2010.

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Kabīruddīn, Muḥammad. Risālah-yi qārūrah. 3rd ed. Lāhaur: Idārah-yi Mat̤būʻāt-i Sulaimānī, 1995.

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Stewart, Cameron J., and Fogazzi G. B, eds. The urinary sediment: An integrated view. London: Chapman & Hall Medical, 1994.

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Cregan, S. P. Bioassay techniques for 55Fe in urine samples. Chalk River, Ont: Health Physics Branch, Chalk River Laboratories, 1993.

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V, Canfield Dennis, White Vicky L, and United States. Office of Aviation Medicine., eds. The analysis of benzodiazepines in forensic urine samples. Washington, D.C: U.S.Dept. of Transportation, Federal Aviation Administration, Office of Aviation Medicine, 1996.

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Book chapters on the topic "Urine analysi"

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Liu, Yongtao, and Jianrui Yin. "Application of Peptide Level and Posttranslational Modifications to Integrative Analyses in Proteomics." In Urine, 49–63. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9109-5_6.

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Neuendorf, Josefine. "Microscopic Urine Sediment: Analysis and Findings." In Urine Sediment, 159–222. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-15911-5_12.

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Henderson, Scott R., and Mark Harber. "Urine Analysis." In Practical Nephrology, 19–28. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-5547-8_2.

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Sharkey, Leslie. "Urine Analysis." In Interpretation of Equine Laboratory Diagnostics, 383–86. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781118922798.ch57.

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Henderson, Scott R., and Mark Harber. "Urine Analysis." In Primer on Nephrology, 29–43. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-76419-7_2.

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Gässler, Norbert, Harald Schlebusch, and Peter B. Luppa. "Urine and stool analyses." In Point-of-Care Testing, 181–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54497-6_19.

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Ridley, John W. "Fecal Analysis." In Fundamentals of the Study of Urine and Body Fluids, 341–55. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78417-5_15.

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Ridley, John W. "Cerebrospinal Fluid Analysis." In Fundamentals of the Study of Urine and Body Fluids, 251–76. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78417-5_11.

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Ridley, John W. "Serous Fluids Analysis." In Fundamentals of the Study of Urine and Body Fluids, 301–22. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78417-5_13.

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Shao, Chen. "Applications of Peptide Retention Time in Proteomic Data Analysis." In Urine Proteomics in Kidney Disease Biomarker Discovery, 67–75. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9523-4_7.

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Conference papers on the topic "Urine analysi"

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Anthimopoulos, Marios, Sidharta Gupta, Spyridon Arampatzis, and Stavroula Mougiakakou. "Smartphone-based urine strip analysis." In 2016 IEEE International Conference on Imaging Systems and Techniques (IST). IEEE, 2016. http://dx.doi.org/10.1109/ist.2016.7738253.

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Mahdy, Tarek, Abdulaziz Al-Sulaiti, Yasser Abdelqader, Abdelrahman Fikry, Gaffar Hag, and Mohammad I. Ahmad. "A Validated and Applicable Direct Injection LC/MS/MS Method of Fourteen Drugs of Abuse in Urine Samples to Avoid the False Positive/Negative Results of Immunoassay Techniques in Forensic Cases." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0146.

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Many false positive and false negative results have been detected in immunoassay analyses of drugs of abuse in urine samples. A method of direct injection of diluted urine into LC/MS/MS was developed and validated for detection and quantitation of Amphetamine, Methamphetamine, MDMA, MDA, Benzoylecgonine, Ecgonine, Norpseudoephedrine, Ephedrine, Tapentadol, Tramadol, O-desmethyltramadol, Tapentadol, Pregabline, Gabapentine and Methadone to avoid the false positive and false negative results in urine samples. Linearity of Amphetamine, Methamphetamine MDMA, MDA, Benzoylecgonine, Ecgonine, Norpseudoephedrine and Ephedrine was (60-2400ng/mL), for Tapentadol, Tramadol, O-desmethyltramadol, and Methadone was (50-1600 ng/mL), and for Pregabline and Gabapentine was (100-4000ng/mL) and r2 ˃ 0.992 for all analysts. A 440 urine samples have been analyzed using both immunoassay technique and LC/MS/MS by direct injection method giving a good comparison to illustrate how this method was specific, accurate, precise, and applicable for forensic urine samples
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Silveira, A. M. V., B. Hessel, and B. Blombäck. "VON WILLEBRAND FACTOR (VWF) ANTIGENS IN URINE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644083.

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Human urine was analyzed using a sensitive enzyme linked immunosorbent assay (ELISA) for von Willebrand factor (VWF) antigen. Urine of healthy persons contained VWF immunoreactivity. In the urine of a patient with severe von Willebrand disease, the VWF antigen was only detectable after intravenous infusion of VWF-Factor VIII concentrate. The VWF antigen in normal urine was analyzed by gel permeation high performance liquid chromatography (HPLC) and gel electrophoresis combined with immunoblotting. These analyses revealed three immunoreactive components of Mr 350 kDa, 60 kDa, and 20 kDa, respectively, the 60 kDa being the major component. Monoclonal antibodies of known specificity to VWF molecule were used in ELISA and immunoblotting to analyze urinary VWF. The three components reacted with an antibody to the central part of VWF, which is called fragment I, and contains the binding site for collagen. No significant immunoreac-tion was observed with monoclonal antibodies to the Nor C-terminal portions of VWF.VWF derivatives of molecular size similar to the largest urinary antigens were also observed in normal plasma. However, there is not an obvious relationship between these plasma forms and the products in urine since reduction of plasma and urine yields different products.These results indicate that VWF antigens excreted in normal urine are most likely fragments of VWF produced by limited degradation in vivo. This degradation preserves the central part of VWF molecule, the one which reacts with the antibody that blocks the binding of VWF to collagen.
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Chicea, D., R. Chicea, L. M. Chicea, Madalin Bunoiu, and Iosif Malaescu. "Using DLS for Fast Urine Sample Analysis." In Proceedings of the Physics Conference. AIP, 2010. http://dx.doi.org/10.1063/1.3482223.

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Zaylaa, Amira J., Rania Ghotmi, and Samara Barakat. "Urine Analysis Device from Research to Design." In 2020 IEEE 5th Middle East and Africa Conference on Biomedical Engineering (MECBME). IEEE, 2020. http://dx.doi.org/10.1109/mecbme47393.2020.9265127.

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Chun-Yan Li, Bin Fang, Yi Wang, Guang-Zhou Lu, Ji-Ye Qian, and Lin Chen. "Automatic detecting and recognition of casts in urine sediment images." In 2009 International Conference on Wavelet Analysis and Pattern Recognition (ICWAPR). IEEE, 2009. http://dx.doi.org/10.1109/icwapr.2009.5207456.

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Walendziuk, Wojciech, Aleksander Sawicki, and Adam Idźkowski. "The use of DTW method as an effective way of uroflowmetry data screening analysis." In Biomdlore. VGTU Technika, 2016. http://dx.doi.org/10.3846/biomdlore.2016.12.

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The aim of this work is to present an application of the Dynamic Time Warping (DTW) method for the preliminary classification of data obtained during uroflowmetric tests. This enables determining whether the recorded data from the urine flow speed measurements is accurate or not. Example urine flow characteristics obtained from a uroflowmeter based on a strain gauge transducer were used in the research. The analysis of the algorithm performance was done on the basis of real tests results of patients with the risk of the prostate hyperplasia occurrence. Moreover, the results of example experiments are presented in this paper.
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Huda, Thorikul, Durotun Nafisah, Suryati Kumorowulan, and Sri Lestari. "Quality control of test iodine in urine by spectrophotometry UV–Vis." In INTERNATIONAL CONFERENCE AND WORKSHOP ON MATHEMATICAL ANALYSIS AND ITS APPLICATIONS (ICWOMAA 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5016017.

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Jones, K., P. Akrill, R. Guiver, and J. Cocker. "56. Biological Monitoring of Nitroglycerin Exposure by Urine Analysis." In AIHce 2002. AIHA, 2002. http://dx.doi.org/10.3320/1.2766408.

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Kavita and Sahil Sharma. "Study of reliability of urine sample in forensic analysis." In ADVANCEMENTS IN CIVIL ENGINEERING: COSMEC-2021. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0120044.

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Reports on the topic "Urine analysi"

1

Mirocha, Chester J., Young B. Kim, Urooj Mirza, Weiping Xie, and Hamed K. Abbas. Analysis of Saxitoxin from Urine Using Dynamic FAB/MS. Fort Belvoir, VA: Defense Technical Information Center, October 1991. http://dx.doi.org/10.21236/ada244960.

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Mirocha, Chester J., Won J. Cheong, and Hamed Abbas. Analysis of Saxitoxin from Urine Using Dynamic FAB/MS. Fort Belvoir, VA: Defense Technical Information Center, July 1990. http://dx.doi.org/10.21236/ada226474.

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Piraner, Olga, Rose T. Preston, Sonoya Toyoko Shanks, and Robert Jones. 90Sr liquid scintillation urine analysis utilizing different approaches for tracer recovery. Office of Scientific and Technical Information (OSTI), August 2010. http://dx.doi.org/10.2172/1097198.

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Sun, L. C., A. R. Moorthy, E. Kaplan, J. W. Baum, and C. B. Meinhold. Assessment of plutonium exposures in Rongelap and Utirik populations by fission track analysis of urine. Office of Scientific and Technical Information (OSTI), September 1994. http://dx.doi.org/10.2172/10181822.

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Wong, C., and L. Collins. TECHNICAL EQUIVALENCE BETWEEN PERKIN-ELMER DRCe AND ELAN 6000 FOR THE ANALYSIS OF 238U IN URINE BIOASSAY SAMPLES. Office of Scientific and Technical Information (OSTI), September 2007. http://dx.doi.org/10.2172/924967.

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Mayer, B., A. Williams, R. Leif, R. Udey, and A. Vu. Extraction of Sulfur Mustard Metabolites from Urine Samples and Analysis by Liquid Chromatography-High-Resolution Mass Spectrometry (LC-HRMS). Office of Scientific and Technical Information (OSTI), August 2014. http://dx.doi.org/10.2172/1165796.

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Zhu, Zhihong, Yue Zhuo, Haitao Jin, Boyu Wu, and Zhijie Li. Chinese Medicine Therapies for Neurogenic Bladder after Spinal Cord Injury: A protocol for systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2021. http://dx.doi.org/10.37766/inplasy2021.8.0084.

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Neurogenic bladder (NB), a refractory disease, is characterized by voiding dysfunction of bladder and/or urethra, and spinal cord injury (SCI) is a common cause. Chinese medicine therapies have been applied extensively in the treatment of neurogenic bladder, especially in China, and the results are promising but varying. Thus, the aim of this work is to assess the efficacy and safety of various Chinese medicine therapies for neurogenic bladder after spinal cord injury. Condition being studied: Chinese medicine therapies; Neurogenic bladder after spinal cord injury. Main outcome(s): The primary outcome of our NMA will be measured by overall response rate and urodynamic tests, which includes postvoiding residual urine volume, maximum urinary flow rate, and maximal detrusor pressure.
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Mayer, B. P., A. M. Williams, R. N. Leif, and A. K. Vu. Extraction of Phosphonic Acids from Urine Samples and Analysis by Gas Chromatography with Detection by Mass Spectrometryand Flame Photometric Detection. Office of Scientific and Technical Information (OSTI), December 2013. http://dx.doi.org/10.2172/1116967.

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Botchkina, Galina I., and Howard L. Adler. Validation of Quantitative Multimodality Analysis of Telomerase Activity in Urine Cells as a Noninvasive Diagnostic and Prognostic Tool for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2005. http://dx.doi.org/10.21236/ada468571.

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Wrenn, M. E., N. P. Singh, and Ying-Hua Xue. Fission track analysis of plutonium in small specimens of biological material: Ultrasensitive analysis for sup 239 Pu in 50 urine samples from the Marshall Islands furnished by Brookhaven National Laboratory. Office of Scientific and Technical Information (OSTI), November 1990. http://dx.doi.org/10.2172/6315643.

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