Journal articles on the topic 'Urinary organs – Diseases'
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1
Stepchenkov, Roman Petrovich. "Indications and Contraindications for Cystography, Diagnostic Value of the Method." Spravočnik vrača obŝej praktiki (Journal of Family Medicine), no. 10 (September 27, 2020): 54–59. http://dx.doi.org/10.33920/med-10-2010-08.
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Diseases of the urinary system are quite common, both among adults and among children. If, in case of infectious and inflammatory diseases of the urinary organs, an assessment of the clinical picture and general analysis of the urine is sufficient to make a diagnosis, in a number of other situations — trauma and rupture of the bladder, abnormalities of its development, malignant neoplasms — visualization of the organ is needed. One of these diagnostic methods is cystography.
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Chemidronov, S. N., A. V. Kolsanov, and G. N. Suvorova. "A new concept of pelvic floor support function: Striated–smooth muscle complex." Pacific Medical Journal, no. 3 (September 21, 2023): 32–38. http://dx.doi.org/10.34215/1609-1175-2023-3-32-38.
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Pelvic floor and perineum muscles play an important role in the formation of an apparatus supporting pelvic organs. The functional insufficiency of myofascial structures frequently leads to the development of urinary and fecal incontinence, erectile dysfunction, prolapse of internal organs, and perineal hernias formation. Back in the 20th century, morphologists focused on the skeletal muscles in pelvic floor and perineum, highlighting their leading role in supporting organs and creating intraabdominal pressure. However, in the past two decades, particular attention has been paid to the smooth muscle structures and their relationship with the musculoskeletal system in the pelvic outlet area. The new concept of the striated–smooth muscle complex provides the basis for revising various aspects of pelvic organ prolapse and urinary and fecal incontinence pathophysiology. We believe that this may lead to improved early diagnosis and prevention of diseases of the pelvic floor and perineum.
3
Varga, Gino, Ulrich Honemeyer, and Kazuo Maeda. "Trophoblastic Diseases." Donald School Journal of Ultrasound in Obstetrics and Gynecology 6, no. 1 (2012): 27–42. http://dx.doi.org/10.5005/jp-journals-10009-1224.
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ABSTRACT Trophoblastic diseases are mainly hydatidiform mole and choriocarcinoma, where the latter is usually the sequela of molar pregnancy and malignant systemic disease with general metastases destructing various tissues and organs till she die. High level urinary hCG, real-time B-mode and color Doppler imaging detect hydatidiform mole in early gestation, postmolar persistent trophoblastic disease is diagnosed by urinary hCG, and treated by prophylactic chemotherapy against choriocarcinoma. Uterine choriocarcinoma and its metastases are diagnosed by hCG and B-mode, color and power Doppler and 3D images detecting rich tumor blood flow. Most choriocarcinoma was effectively treated by primary chemotherapy with methotrexate, etoposide, etc. Until complete remission where hCG is lower than the cut-off level. Placental site trophoblastic tumor (PSTT) and epitheloid trophoblastic tumor (ETT) were low in hCG level and high in human placental lactogen (hPL), and show rich tumor blood flow in color Doppler ultrsound. Nongestational choriocarcinoma is rare and usually chemotherapy resistant. How to cite this article Maeda K, Kurjak A, Varga G, Honemeyer U. Trophoblastic Diseases. Donald School J Ultrasound Obstet Gynecol 2012;6(1):27-42.
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Eberman, A. L. "ABOUT FEMALE URETRIT." Journal of obstetrics and women's diseases 5, no. 5 (August 7, 2020): 435–44. http://dx.doi.org/10.17816/jowd55435-444.
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I hope that my comrades will not condemn me for such an apparently insignificant topic, which I have chosen for today's report; I chose her because they paid and pay little attention to the urethritis of women and, in general, to the diseases of their urinary canal, - and very little about the diseases of this canal comes across in the manuals; a more extensive treatise we find in the surgery of Pitha-Billroth T. XI, processed by Winckel. In gynecology of various authors about diseases of urinary organs, it is said in passing and, in general, very little. And it is very understandable that gynecologists, busy with a more important organ - the organ of support of the human race, pay little or no attention to this small vessel - the urethra; but this short water supply of the female body does not easily cause not a little suffering, which is often attributed to uterine suffering, between which he is the cause of all suffering.
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Arkhipov, Evgenii V., Railya V. Garipova, and Leonid A. Strizhakov. "Occupational malignant neoplasms of the kidney and urinary tract." Russian Journal of Occupational Health and Industrial Ecology 63, no. 12 (December 29, 2023): 835–40. http://dx.doi.org/10.31089/1026-9428-2023-63-12-835-840.
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The epidemiological characteristics of many occupational lesions of the urinary tract organs remain poorly understood and unspecified, since they are described only as sporadic individual or group cases.
Diseases arising from exposure to industrial carcinogens remain an urgent problem in occupational health. Unfortunately, today there is a low detection rate of occupational malignancies of any localization. Occupational oncological diseases with damage to the kidneys and urinary tract develop as a result of direct contact with a production factor with a carcinogenic effect.
The analysis of the conducted studies devoted to the problem of occupational oncological lesions of the kidneys and urinary tract, the frequency of which remains underestimated due to their latent clinical course and the influence of environmental factors, which requires further study of this issue.
For timely diagnosis of malignant neoplasms of the urinary system organs after reaching the length of service of five years, it is recommended to conduct an ultrasound examination of the kidneys and urinary tract and cystoscopy once every five years at the center of occupational pathology for persons working in contact with carcinogens.
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Shumytskyi, A. V., O. A. Burka, and T. M. Tutchenko. "Criteria for the diagnosis of infectious lesions of the lower urinary tract and pelvic organs." HEALTH OF WOMAN, no. 10(146) (December 30, 2019): 101–4. http://dx.doi.org/10.15574/hw.2019.146.101.
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Urinary tract infections are the third most prevalent in humans after respiratory and gastrointestinal infections. In fact, bacterial infections of the urinary tract are the most common cause of both hospital and community hospital infections in patients. Pelvic inflammatory diseases (PID) are infectious inflammatory diseases of the upper female genital tract. In addition, the infection can also spread to the abdomen. The classic patient with a high risk of developing a PMTCT is, first and foremost, a woman with multiple sexual partners and unprotected sex. Key words: urethritis, PID, laboratory diagnostics, PCR, cultural research.
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Maltsev, S. V. "EVOLUTION OF IDEAS ABOUT URINARY SYSTEM INFECTION IN CHILDREN." Pediatria. Journal named after G.N. Speransky 101, no. 3 (June 17, 2022): 199–204. http://dx.doi.org/10.24110/0031-403x-2022-101-3-199-204.
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The article presents information on the terminological concepts in the diagnosis of inflammatory diseases of the organs of the urinary system (OUS), as well as the existing views on the criteria for their diagnosis. The modern views on the microbiome and virom of the urinary system, their role in the development of inflammatory diseases in the OUS and the pathways of invasion of infection into the kidneys. The causes, mechanisms of development and progression of renal infection are isolated, including the importance of the structural kidney anomalies and urinary tract, the role of formation of inflammasomes, biofilm and intracellular bacterial communities. Special attention is paid to modern approaches to the prevention and treatment of urinary system infections in children.
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Zakharova, I. N., I. M. Osmanov, E. B. Machneva, E. B. Mumladze, O. V. Brazhnikova, A. N. Gavelya, A. N. Kasyanova, and I. N. Lupan. "Urinary cylinders: what pediatrician and nephrologist need to know." Medical Council, no. 11 (July 18, 2019): 118–25. http://dx.doi.org/10.21518/2079-701x-2019-11-118-125.
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Clinical urine test with the correct interpretation can help the clinician in the diagnosis of the urinary system diseases, as well as other organs and systems. Most laboratories in medical institutions are currently switching to an automated urinary sediment test, but microscopy appears relevant. Unfortunately, clinicians often interpret only three or four (most often proteinuria, leukocyturia and erythrocyturia) of all the numerous indicators of urine test, unfairly ignoring the others. The urinary cylinders are one of these important elements of the urinary sediment. The article presents the characteristics of the main types of urinary cylinders, their origin, composition, morphology and clinical significance.
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Simon, Vasile, Sorin Marian Dudea, Nicolae Crisan, Vasile Dan Stanca, Marina Dudea-Simon, Iulia Andras, Zoltan Attila Mihaly, and Ioan Coman. "Elastography in the Urological Practice: Urinary and Male Genital Tract, Prostate Excluded—Review." Diagnostics 12, no. 7 (July 16, 2022): 1727. http://dx.doi.org/10.3390/diagnostics12071727.
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The aim of this article is to review the utility of elastography in the day-to-day clinical practice of the urologist. An electronic database search was performed on PubMed and Cochrane Library with a date range between January 2000 and December 2021. The search yielded 94 articles that passed the inclusion and exclusion criteria. The articles were reviewed and discussed by organ, pathology and according to the physical principle underlying the elastographic method. Elastography was used in the study of normal organs, tumoral masses, chronic upper and lower urinary tract obstructive diseases, dysfunctions of the lower urinary tract and the male reproductive system, and as a pre- and post-treatment monitoring tool. Elastography has numerous applications in urology, but due to a lack of standardization in the methodology and equipment, further studies are required.
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Mikhailov, M. K., R. F. Akberov, K. Sh Ziyatdinov, and A. Z. Appakova. "Ray methods of investigation in the diagnosis of hepatopancreatoduodenal region and urinary system organs diseases." Kazan medical journal 74, no. 2 (April 15, 1993): 150–55. http://dx.doi.org/10.17816/kazmj64648.
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Based on the examination of 617 patients, using current ray investigation methods sonography, roentgenological methods, computer aided tomograpgy, relaxative duodenography, the authors have determined their resolving capacity in the diagnosis of hepatopancreatoduodenal region and urinary system organs diseases. It is stated that their integral application allows to make a correct diagnosis in 98% of observations.
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Iancu, Mihaela Adela, Laura Maria Condur, Camelia Cristina Diaconu, and Dumitru Matei. "Reno-urinary changes during pregnancy and monitoring of the pregnant woman in primary care." Romanian Medical Journal 68, no. 1 (March 31, 2021): 52–55. http://dx.doi.org/10.37897/rmj.2021.1.9.
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During pregnancy, anatomical and functional changes occur in all organs and systems of the body. The family doctor evaluates the morphofunctional changes in the reno-urinary system throughout the pregnancy. These morphological and functional changes often have no clinical expression. Morphofunctional changes in the reno-urinary system cause changes in laboratory tests results and are the basis for the appearance of urinary tract symptoms. The family doctor has an important role in assessing the pregnant woman, and in diagnosing renal pathology early. Although the pregnant woman has an increased risk of developing various urinary tract diseases, frequently, under active monitoring and conservative treatment, the evolution can be favorable.
12
Mitchenko, M. V. "Estimation of chronic inflammatory diseases of the pelvic organs in women as a risk factor of acute uncomplicated pyelonephritis." HEALTH OF WOMAN, no. 10(146) (December 30, 2019): 97–100. http://dx.doi.org/10.15574/hw.2019.146.97.
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The objective: to study the prevalence of chronic inflammatory diseases of the pelvic organs (CIDPO) in women of reproductive age with acute uncomplicated pyelonephritis (AUP), and clinical peculiarities of pyelonephritis further justification for personalized therapy exposure to all sources of infection. Materials and methods. The survey was conducted by a urologist and gynecologist of 246 women of reproductive age with AUP and concomitant CIDPO. In addition, before the start of antibacterial therapy, material was collected: scrapings of the mucous membranes of the urethra, cervical canal, and vaginal washings. The complex of methods of microbiological diagnostics has been applied: cultural, culture-enzymatic, molecular-genetic. Results. In patients with AUP and concomitant CIDPO, a high rate of infections by the mollicutes was detected in urinary and genital tracts – 69.5% and 67.5%, respectively. Mollicutes were more frequently found in the urinary tract in association with classical bacteria (45.1%), and in the genital tract – in monoculture (44.7%). Importantly, in 65.8% of cases, there was a coincidence of identified pathogens by taxonomic affiliation, indicating that these pathogens are involved in the development of the inflammatory process in both the genital and urinary tracts. The proposed scheme, with the obligatory identification of pathogens of genital infections, allowed to establish that after standard urological treatment, more than two-thirds of patients require additional antibacterial therapy aimed at eradication of urinary and genital tracts of the mollicutes as pathogenic pathogens. Conclusion. The obtained results have allowed to substantiate the need for additional therapy aimed at eradication of mollicutes and to propose an algorithm of microbiological diagnostics to identify the etiological factors of AUP, to develop and implement a new approach to treatment: personalized antimicrobial therapy on all source of pathogens in the urinary and genital tracts. Key words: acute uncomplicated pyelonephritis, women of reproductive age, chronic inflammatory diseases of the pelvic organs, mollicutes, treatment.
13
Kryzhanivska, O. O. "IRIS CHANGES AT PATIENTS WITH TEMPORОMANDIBULAR JOINT DISEASES AND URINARY SYSTEM PATHOLOGY." Medical Science of Ukraine (MSU) 16, no. 4 (December 30, 2020): 28–34. http://dx.doi.org/10.32345/2664-4738.4.2020.5.
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Relevance. In recent years, many have been devoted to the problem of the temporomandibular joint (TMJ) diseases, in which the attention is paid to the widespread pathology of TMJ in young people, which develops against the background of the genetically-determined weakness of connective tissue (CTs), which is also the present occurrence of various concomitant diseases of polygenic-multifactorial nature, including the organs of the urinary system (US).
The study of the state of the iris is used as a screening technique that allows you to quickly, simply, harmlessly, informatively, painlessly, non-invasively diagnose the genetically determined structural and functional state and quality of the CTs.
Objective. To investigate the iris changes in patients with TMJ and US diseases, to reveal the dependence of the occurrence of degenerative-dystrophic and destructive-inflammatory changes in the joints and US on the structural and functional state of the CTs, to supplement the known traditional methods of diagnosing genetically determined CTs weakness.
Materials and methods. The study involved 54 patients (men – 14, women – 40), whose average age was 37.3±7.6 years, who were treated at the Dental Medical Center of the Bogomolets NMU. Control group – 22 patients (men – 10, women – 12) without general somatic pathology, with a physiological bite, without signs of TMJ diseases, whose average age was 25.7±6.8 years. Main group – 22 patients (men – 4, women – 28) with TMJ diseases and US pathology, whose average age was 31.6±7.7 years.
Iridobiomicroscopy was performed in patients of both groups. Iridogenetic constitutional signs were determined: the color of eyes, constitutional type after E.S. Velkhover, type with the connective tissue weakness after I. Deck, the density of iris stoma.
The obtained laboratory data were referenced in the International System of Units and processed by variational statistics using MedStat and EZR v.1.35 (Saitama Medical Center, Jichi Medical University, Saitama, Japan, 2017), which is a graphical interface to RFSC (The R Foundation for Statistical Computing, Vienna, Austria).
Results. Among the examined patients with TMJ diseases and MVS pathology, 75% showed predominantly light eye color and V degree (46.9%) of iris stroma density, in the control group: dark iris color (54.5%) and II degree (68.2%) of iris density.
Iridogenetic constitutional signs of the CT weakness in the patients with TMJ diseases have been determined: the light color of eyes, radial-lacunar constitutional type after E.S. Velkhover (75%), lymphatic constitutional type with the connective tissue weakness after I. Deck (57,9%).
Structural local or chromatic changes of the iris stroma in the projection region of the kidney (75%) and bladder (43.6%) in young patients with TMJ diseases showed a congenital weakness of the CTs of these organs and a tendency to develop pathology of the US.
Conclusions. Patients with degenerative-dystrophic and destructive-inflammatory diseases of the TMJ and concomitant US pathology are characterized by iridogenetic constitutional signs of the CTs weakness in the patients with TMJ diseases have been determined: the light color of eyes, radial-lacunar constitutional type after E.S. Velkhover, low degree of iris stroma density, lymphatic constitutional type with the connective tissue weakness after I. Deck.
Structural local or chromatic changes of the iris stroma in the projection region of the kidney and bladder in young patients with TMJ diseases showed a congenital weakness of the CTs of these organs and a tendency to develop pathology of the US.
It can be assumed that the development of TMJ diseases in young patients is based on dysplastic changes in the CTs system, which is additionally manifested in the examined patients by pathological changes in the US.
Iridobiomicroscopy, as a screening technique for determining the structural and functional state of CTs, makes it possible to increase the accuracy of diagnostics when examining patients with TMJ diseases who have concomitant pathology of internal organs, including US.
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Amit Kumar Singh, Mishra S.S., and Arun Kumar Dwivedi. "Observational Study to evaluate the role of Ultrasonography and X-Ray in Urinary Disease." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (February 8, 2020): 1206–9. http://dx.doi.org/10.26452/ijrps.v11i1.1959.
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Urinary diseases are very common in our society which system constitutes kidneys ureters urinary bladder and urethra various abnormalities occur in these organs due to many reasons like infection inflammation metabolic abnormalities neoplastic changes trauma etc. these abnormalities lead to various physical problems ending into death many times the abnormalities of urinary system can be diagnosed by hematological examination urine analysis radiological examination and histopathological examination especially radiological examination provide wide range of diagnosis of disease of urinary system of almost all origin although various radiological technique like X-ray (plain and contrast) Ultrasonography CT scan MRI and many others are available but in present study X-ray (plain and contrast ) and ultrasonography were used for diagnosis of disease of urinary system because of its easy availability and affordability the diseases of urinary system has been described under the name of Mutrakrichha and Mutraghata in ayurveda these two conditions are in fact group of clinical entities in which urination is difficult and retention is present respectively further they are divided into various subtypes these conditions resembles clinically with various types of urinary diseases early diagnosis has been the always advocated by ayurveda by virtue of this prevention and management becomes easy in the present study written informed consent has been taken from all the patients early detection of these conditions facilitates the management otherwise renal failure may complicate the condition
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Malki Mohamed Amine, Ouaddane Alami R, Cheikh Saad bouh khataraty, Ahsaini M, Mellas S, Ammari JE, Tazi MF, El Fassi MJ, and Farih MH. "Ectopic kidney: Associated diseases and treatment." World Journal of Advanced Research and Reviews 21, no. 2 (February 28, 2024): 967–78. http://dx.doi.org/10.30574/wjarr.2024.21.2.2464.
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Ectopic kidney (or “renal ectopia”) describes a kidney that isn’t located in its usual position. The pelvic kidney is a rare congenital urinary malformation. However, it is the most common type of “ectopic” kidneys. It results from a lack of migration of the metanephros which remains in the pelvic position. It is often smaller than a kidney in the lumbar position, but functional. It can be associated with other malformations (urological, vascular, etc.), or present complications such as urolithiasis, hydronephrosis, urinary infection or even tumor. In that case , Urolithiasis is the most common pathology of the pelvic kidney, it can be a source of serious complications. Its discovery requires an etiological investigation in search of a hereditary, metabolic or even infectious disease. In practice, renal pelvic ectopia poses various diagnostic problems; the close relationships of ectopic kidneys with neighboring organs explain the borrowed semiology and diagnostic errors. Alongside medical care, urological care is essential. The choice of treatment in pelvic kidney pathology depends on the pathology in question, its clinical and biological repercussions, as well as the patient's condition and its comorbidities. The use of open surgery and/or laparoscopy in cases of lithiasis pelvic kidney must remain exceptional after having eliminated all possibilities of LEC and endourology surgery.
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Cabioglu, Mehmet Tugrul, and Gülnaz Arslan. "Neurophysiologic Basis of Back-Shu and Huatuo-Jiaji Points." American Journal of Chinese Medicine 36, no. 03 (January 2008): 473–79. http://dx.doi.org/10.1142/s0192415x08005916.
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Acupuncture, a method of traditional Chinese medicine that uses Back-Shu and Huatuo-Jiaji points, is especially effective for treating diseases of the visceral organs. Applying acupuncture on Back-Shu points affects visceral organs in many ways. For example, it dilates the bronchus, affects the heartbeat, stomach motility, urinary bladder contractions and so on. Acupuncture's effects can be explained as viscero-cutaneous, cutaneo-visceral, cutaneo-muscular, and viscero-muscular reflexes. Segmental dispersion of the sympathetic and parasympathetic systems is related to the location of Back-Shu points. Changes in visceral organs caused by application of acupuncture can be explained as modulation of the sympathetic and parasympathetic systems.
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Leonov, M. G., E. S. Kharbandaridi, G. A. Rakhuba, D. E. Istomina, and S. N. Chernov. "Study of the Role of Professional Factors in the Occurrence of Neoplasms in Employees of Port Enterprises of Novorossiysk." Effective Pharmacotherapy 19, no. 15 (May 29, 2023): 18–22. http://dx.doi.org/10.33978/2307-3586-2023-19-15-18-22.
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According to the scientific literature, when studying the health status of workers engaged in various activities at port enterprises, it was revealed that they have a high risk of diseases of the visual organs, pathology of the ent organs and the endocrine system. A number of researchers believe that working at the port is a factor that increases the risk of diseases of the urinary system. According to other data, port work increases the risk of cardiovascular diseases. Many authors have presented results confirming the negative impact of professional activity in the port on human health, which increases the risk of developing such chronic non-communicable diseases as diabetes mellitus and malignant neoplasms. The increase in cancer incidence remains a problem worldwide, and advances in diagnosis and treatment do not lead to a significant reduction in morbidity and mortality. Undoubtedly, the priority reasons determining the growth of oncological morbidity of the population are various environmental factors, including occupational harmfulness.
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Sultana, Mst Atia, Monira Akter, Tahmina Noor, and Mahbub Hossain. "Study of disease pattern of patients admitted in Gynae & Obst. Department in a rural tertiary medical institute." KYAMC Journal 3, no. 1 (February 5, 2013): 220–22. http://dx.doi.org/10.3329/kyamcj.v3i1.13656.
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The aim of this study was to find out the Gynaecological disease pattern, common diseases, age distribution , organs involvement of female reproductive system, types of diseases etc. in admitted patient of Khwaja Yunus Ali Medical College & Hospital (KYAMCH) a rural tertiary hospital in Bangladesh. In this retrospective & descriptive study total 853 Gynaecological patients were evaluated in 4 years period, who were admitted either from OPD or through emergency. Most of the diagnosis were made after evaluation of organ involvement, 53% uterine origin, most are benign 29%; 40% patient having normal menstrual cycle but suffering from Gynaecological diseases like chronic cervicitis, lower abdominal pain(PID). Vaginal discharge, urinary tract infection, ectopic pregnancy, different types of abortion. This study showed that the Gynaecological disease pattern of Patients admitted in Obs& Gynae department of KYAMCH- a rural tertiary medical institute.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13656 KYAMC Journal Vol. 3, No.-1, June 2012 pp.220-222
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Zhdan, V. M., Ye M. Kitura, M. Yu Babanina, O. V. Gordiienko, and T. V. Moroz. "INFECTIOUS COMPLICATIONS IN A PATIENT WITH SYSTEMIC SCLERODERMA AND MULTIPLE ORGAN DYSFUNCTION: A CASE REPORT." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 20, no. 1 (April 9, 2020): 222–25. http://dx.doi.org/10.31718/2077-1096.20.1.222.
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Systemic scleroderma is an autoimmune connective tissue disease with characteristic lesions of the skin, blood vessels, musculoskeletal system and internal organs (kidneys, heart, lungs, and digestive tract) based on impaired microcirculation, inflammation and generalized fibrosis. At the stage of provisional diagnosis, the triad of the initial signs of the disease is especially important including Raynaud’s syndrome, characteristic skin lesions, and joint syndrome. Subsequently, multiple organs and tissues are involved in the process. Infectious complications are one of the major threats to patients with systemic connective tissue disease, along with cardiovascular and cancerous diseases. Based on retrospective analysis, it has been found out that the incidence of comorbid infections in the in-patients with rheumatic diseases made up 9.7%; with predominant damage to respiratory organs was 44%, urinary tract – 29.2%, and skin and soft tissues – 18.9%. Comorbid infections were the most common in patients with systemic lupus erythematosus (28.4%) and rheumatoid arthritis (13.2%). Infections constitute 2-9% of overall causes of mortality in patients with systemic scleroderma. Cases of serious infections (pneumonia, sepsis, bacterial arthritis, skin and soft tissues lesions, etc.) have been recorded, including those with fatal outcomes. The problem of differential diagnosis of systemic infectious process and rheumatic diseases with high activity is extremely important. The paper presents a clinical case of subacute course of systemic scleroderma with multiple organ dysfunction affecting lungs (pneumofibrosis, pulmonary hypertension), heart (restrictive cardiomyopathy, atrial flutter), kidneys (nephritis) conjoined with severe infectious complications (septicemia, phlegmon of the soft tissues of the left leg). The present clinical case clearly demonstrates a severe subacute course with multiple organ dysfunction affecting lungs, heart, kidneys, digestive tract. Immunodeficiency was accompanied by severe infectious complications, in particularly, septicemia, soft tissue phlegmon, having complex pathogenesis that required prolonged intensive care.
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Pukhova, T. G., O. N. Chirkova, E. P. Sitnikova, K. V. Dashichev, and I. A. Leontiev. "Epidemiology and clinical features of congenital malformations of uri-nary system organs in conditions of environmental distress." Perm Medical Journal 37, no. 6 (January 28, 2021): 54–60. http://dx.doi.org/10.17816/pmj37654-60.
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Objective. To establish the features of epidemiology and clinical manifestations of congenital malformations of the urinary system in the zone of environmental distress.
Material and methods. We analyzed the overall prevalence of nephropathies and the proportion of congenital malformations of the urinary system in the dynamics from 2001 to 2019; 697 patients aged 118 years were examined with assessment of clinical and anamnestic, laboratory, instrumental and radiological data in accordance with diagnostic standards and protocols. We studied the features of epidemiology and clinical manifestations of congenital kidney and urinary tract diseases in an area with an unfavorable environmental situation.
Results. Over the past 2 decades, the general prevalence of nephropathies in the children's population has increased with an elevation in the proportion of congenital malformations of the urinary system. These indicators are significantly higher in an area with a high level of anthropogenic environmental pollution than in an area with a relatively favorable environmental situation. Features of congenital pathology of the kidneys and urinary tract in patients living in an environmentally unfavorable zone were revealed: the presence of mass deficiency, reduced resistance, combination with undifferentiated connective tissue dysplasia syndrome, more frequent attachment of microbial-inflammatory process, decreased concentration and evacuation function of the kidneys.
Conclusions. These features of epidemiology and clinical manifestations of congenital malformations of the urinary system in patients living in a region with a high level of environmental pollution should be taken into account when carrying out their medical support.
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Smirnova, N. N., N. B. Kuprienko, V. P. Novikova, and A. I. Khavkin. "Iron metabolism and chronic kidney disease." Voprosy detskoj dietologii 18, no. 6 (2020): 27–34. http://dx.doi.org/10.20953/1727-5784-2020-6-27-34.
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Iron is involved in all kinds of metabolism. Iron deficiency, even in the absence of anaemia, promotes the development of many diseases. But in inflammation-associated diseases iron accumulates in the liver, kidneys and macrophages; resulting in impairment of effective erythropoiesis. The review presents modern evidence of the molecular mechanisms of iron metabolism and metabolic changes in most common diseases of the organs of the urinary system – pyelonephritis, glomerulonephritis, acute kidney injury. In most cases, anaemia has a dual nature – true iron deficiency anaemia and anaemia of chronic disease. Key words: iron, erythropoiesis, anaemia, renal pathology
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Pugia, Michael J., and John A. Lott. "Pathophysiology and diagnostic value of urinary trypsin inhibitors." Clinical Chemistry and Laboratory Medicine (CCLM) 43, no. 1 (January 1, 2005): 1–16. http://dx.doi.org/10.1515/cclm.2005.001.
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AbstractInflammation is an important indicator of tissue injury. In the acute form, there is usually accumulation of fluids and plasma components in the affected tissues. Platelet activation and the appearance in blood of abnormally increased numbers of polymorphonucleocytes, lymphocytes, plasma cells and macrophages usually occur. Infectious disorders such as sepsis, meningitis, respiratory infection, urinary tract infection, viral infection, and bacterial infection usually induce an inflammatory response. Chronic inflammation is often associated with diabetes mellitus, acute myocardial infarction, coronary artery disease, kidney diseases, and certain auto-immune disorders, such as rheumatoid arthritis, organ failures and other disorders with an inflammatory component or etiology. The disorder may occur before inflammation is apparent. Markers of inflammation such as C-reactive protein (CRP) and urinary trypsin inhibitors have changed our appraisal of acute events such as myocardial infarction; the infarct may be a response to acute infection and (or) inflammation.We describe here the pathophysiology of an anti-inflammatory agent termed urinary trypsin inhibitor (uTi). It is an important anti-inflammatory substance that is present in urine, blood and all organs. We also describe the anti-inflammatory agent bikunin, a selective inhibitor of serine proteases. The latter are important in modulating inflammatory events and even shutting them down.
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Наталья Эдуардовна, Прокопьева,, Новикова, Валерия Павловна, and Хавкин, Анатолий Ильич. "GUT MICROBIOTA - KIDNEY AXIS. FEATURES IN DISEASES OF THE URINARY SYSTEM AND UROGENITAL TRACT." Medicine: theory and practice, no. 4 (January 13, 2023): 68–77. http://dx.doi.org/10.56871/mtp.2022.51.41.008.
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В последние годы вызывает повышенный интерес взаимодействие микробиоты кишечника и различных органов, растет количество данных, свидетельствующих о важности оси кишечник почки при почечных заболеваниях. Достижения в области секвенирования кишечного микробиома, связанных метаболитов, определения проницаемости кишечника и воспаления обеспечивают новые терапевтические стратегии, нацеленные на кишечник при заболеваниях почек. In recent years, there has been increased interest in the interaction between the gut microbiota and various organs, and there is growing evidence of the importance of the gut kidney axis in renal disease. Advances in gut microbiome sequencing, associated metabolites, gut permeability, and inflammation provide novel therapeutic strategies targeting the gut in kidney disease.
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Kryzhanivska, O. O. "MANIFESTATIONS OF URINARY SYSTEM PATHOLOGY AT YOUNG AGE PATIENTS WITH TEMPORОMANDIBULAR JOINT DISEASES." Medical Science of Ukraine (MSU) 15, no. 3-4 (December 26, 2019): 54–58. http://dx.doi.org/10.32345/2664-4738.3-4.2019.08.
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Relevance. In recent years, many have been devoted to the problem of the temporomandibular joint (TMJ) diseases, in which the attention is paid to the widespread pathology of TMJ at young people, which develops against the background of genetically-determined weakness of connective tissue (CT), which is also present occurrence of various concomitant diseases of polygenic-multifactorial nature, including the organs of the urinary system (US).
Objective. To investigate the manifestations of US pathology in young patients with TMJ diseases.
Materials and methods. The study involved 32 patients (m-4, w-28) with diseases of the TMJ, whose average age was 31.6 ± 7.7 years, who were treated at the Dental Medical Center of the Bogomolets NMU. Manifestations of US pathology in patients of this group have been investigated.
Examination of patients was performed according to the classical method of examination of patients with diseases of the TMJ. The orthopantomography with examination of the mandibular heads, open mouth X-ray by Parma, computed tomography or MRI scan, iridobiomicroscopy were obligatory. The presence of pathology of US was founding out from the anamnesis vitae, the patient was referred for consultation to a nephrologist. Ultrasound of the kidneys, urinary tract, urine tests were performed for all examined patients.
The obtained laboratory data were referenced in the International System of Units and processed by variational statistics using MedStat and EZR v.1.35 (Saitama Medical Center, Jichi Medical University, Saitama, Japan, 2017), which is a graphical interface to RFSC (The R Foundation for Statistical Computing, Vienna, Austria).
Results. The following manifestations of TMJ pathology were found in young patients with US diseases: chronic cystitis – 37.5% of cases, oxalate or urinary crystalluria – 37.5 %, nephroptosis – 9.4 %, urolithiasis – 6.3 %, chronic pyelonephritis – 6.3 %, double kidney – 3.1 %.
Structural local or chromatic changes of the iris stroma in the projection region of the kidney (75 %) and bladder (43.6 %) in young patients with TMJ diseases showed a congenital weakness of the CT of these organs and a tendency to develop pathology of the US.
Changes in urine tests were mainly in the form of oxalate crystalluria (34.4 %), increase specific gravity (15.6 %), proteinuria (9.4 %), which further confirmed the present pathology of the urinary system.
Conclusions. The manifestations of developmental abnormalities and other kidney and bladder diseases found in young patients with TMJ disease suggest that there is a correlation between flow of pathological processes in the TMJ and US, which may be based on changes in the CT system.
When planning the treatment of young patients with TMJ diseases and pathology of US, medicines that do not affect the urinary system and do not provoke exacerbation of the disease should be prescribed. In the presence of pathology of the kidneys and/or urinary tract, the ultrasound of this system should be prescribed in consultation with a nephrologist.
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B. Yu. Banul and D. V. Pronyayev. "MORPHOMETRICAL PARAMETRS OF PARAMESONEPHRIC DUCTS AND THEIR DE-RIVATIVES AT THE BEGINNING OF THE FETAL PERIOD OF HUMAN ONTOGENESIS." Clinical anatomy and operative surgery 17, no. 3 (August 28, 2018): 58–63. http://dx.doi.org/10.24061/1727-0847.17.3.2018.9.
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An important condition to understand etiopathogenesis of gynecological diseases is improvement of examination of fetal morphogenesis concerning the urinary system and other organs. For example, chronic pelvic ache can result from a wide range of disorders: endometriosis, myoma, commissures, cystitis, colitis, pathology of the femoral joint and diseases of the pelvic bones. Meanwhile the majority of these diseases can be diagnosed, prevented or treated during antenatal period. 50 specimens of human fetuses were examined by means of a complex of morphological methods in order to study morphogenesis of the internal female reproductive organs at the beginning of the uterine period. The article deals with the features of the development of paramesonephric ducts and their derivatives at the beginning of the fetal period of human ontogenesis. At the beginning of the fetal period the position and shape of the fallopian tubes are found to be caused by close correlations with the adjacent organs and structures. From three to six narrow portions are formed along the uterine tube. The morphometric parameters of the ampulla of the fallopian tubes vary depending on the age of the fetus.
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Maxmudovich, Akhmedov Yusuf, Mavlonov Nurbek Nizomovich, Turayev Sukhrob Ortikovich, and Mukhsinov Sardorbek Uktamovich. "MEGAURETHIR IN CHILDREN: METHODS OF ENDOSCOPIC CORRECTION." European International Journal of Multidisciplinary Research and Management Studies 4, no. 4 (April 1, 2024): 8–13. http://dx.doi.org/10.55640/eijmrms-04-04-02.
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Megaureter is a severe pathology of the urinary system. According to the World Health Organization, according to the number and structure of diseases, malformations of the urinary system organs in children occupy one of the leading places among pathologiesof all organs and systems. The purpose of the study was to determine the effectiveness of endoscopic methods for correcting megaurethritis in children. The study presents the results of treatment of 116 patients with refluxing and obstructive megaureter on the basis of the Department of Pediatric Surgery No. 2 Samara State Medical University for the period from 2010 to 2022. The results of the examination revealed that the urodynamic characteristics of positive results after endoscopic correction of megaureter in a period of 3-6 months indicated a clear depending on the treatment results from the method of forming a bolus in the area of the ureterovesical segment: for mild severity, the STING method was effective, for moderate severity -HITI, and for severe severity -HITII.
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Kovalevskiy, Evgeny, and Sergey Kashanskiy. "P-123 EVALUATION OF THE CAUSES OF DEATH OF PATIENTS WITH ESTABLISHED DIAGNOSIS OF ASBESTOSIS." Occupational Medicine 74, Supplement_1 (July 1, 2024): 0. http://dx.doi.org/10.1093/occmed/kqae023.0630.
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Abstract Introduction In assessing the prevalence of diseases potentially associated with asbestos exposure the mortality rates are recognized as the most reliable index. But this indicator does not allow to estimate the prevalence of asbestos-related diseases, which are often not indicated in death certificates as the main cause of death, such as asbestosis. Methods Initial review of the causes of death in a group of 850 chrysotile asbestos mining and enrichment workers with diagnosis “asbestosis” established in the territorial center of occupational health from 1946 to 2020 carried out using death certificates’ national electronic database. Results 210 workers of the group died. The average age of deceased was over 60 years old. The peak age of mortality was for women 71-80 years, for men 61-70. Asbestosis was identified as the main cause of death for only 9 patients (3 men and 6 women). Most of the death causes (46.1%) were diseases of the circulatory system, malignant neoplasms (32.0%). In men, the main cancer sites were respiratory and chest organs (56.7%), digestive (20.0%), urinary tract (13.3%). Women died more often from cancer of the digestive organs (37.8 %), respiratory organs and chest (27.6%), female genital organs (13.8%) and breast (10.3%). The third ranking place was respiratory diseases (8.3%). Discussion/Conclusion Even initial review demonstrated that asbestosis itself in modern conditions is practically not considered as the main cause of death, which indicates the need for a wider study of the incidence of non-malignant occupational asbestos-related diseases in the country with special attention to exposure conditions, occupational history and lifestyle factors.
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Rashid, Sameeah Abdulrahman. "Prevalence and clinical potential of extraspinal incidental findings in lumbosacral spine MRI of patients with suspected disc diseases." Medical Journal of Indonesia 30, no. 4 (December 23, 2021): 256–63. http://dx.doi.org/10.13181/mji.oa.215550.
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BACKGROUND Incidental findings could be observed in organs close to the spine while reporting lumbosacral spine magnetic resonance imaging (MRI). This study aimed to report the prevalence and clinical potential of extraspinal incidental findings in lumbosacral MRI of patients with suspected disc diseases.
METHODS This single-centered cross-sectional study was carried out on 420 consecutive adult patients who underwent lumbar spine MRI for suspected disc disease from January to July 2019. The MRI was checked for the presence of extraspinal incidental findings, and each finding was categorized according to the body organ and its clinical significance. Each MRI plane that best displayed the findings was recorded, and the association between the findings and patient's age and sex was determined.
RESULTS Of 420 samples, 135 cases showed extraspinal findings (32.1%), and 7.6% of the patients displayed suspicious lesions. The urinary tract was the most common system (18.6%) to display both clinically significant (5.0%) and benign findings (13.6%), and the axial MRI section was the plane which showed most of the incidental findings. Incidental findings in any body system were rarely found in the younger patients. Females had significantly higher benign findings than males (p = 0.002).
CONCLUSIONS The prevalence of extraspinal findings in lumbosacral spine MRI is high, and some are significant. Most findings are related to the urinary tract and best displayed in the axial plane.
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Gomes, Cristiano M., Sami Arap, and Flávio E. Trigo-Rocha. "Voiding dysfunction and urodynamic abnormalities in elderly patients." Revista do Hospital das Clínicas 59, no. 4 (2004): 206–15. http://dx.doi.org/10.1590/s0041-87812004000400010.
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Lower urinary tract dysfunction is a major cause of morbidity and decreased quality of life in elderly men and women. With the progressive aging of the population, it is important to understand common micturitional disorders that may occur in this population. Most urinary problems in the elderly are multifactorial in origin, demanding a comprehensive assessment of the lower urinary tract organs, functional impairments, and concurrent medical diseases. Urodynamics is a highly valuable tool in the investigation of elderly patients with lower urinary tract symptoms. Urodynamic tests are not always necessary, being indicated after excluding potentially reversible conditions outside the urinary tract that may be causing or contributing to the symptoms. Although urodynamic tests may reveal common diagnoses such as bladder outlet obstruction and stress urinary incontinence in the elderly population, findings such as detrusor overactivity and impaired detrusor contractility are common and have important prognostic and therapeutic implications. The purpose of this article is to describe common urologic problems in the elderly and review the indications for and clinical aspects of urodynamic studies in these conditions.
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Khomenko, Z. V., I. M. Sokulskyi, and S. S. Zaika. "Morphological characteristics of the kidneys of mature dogs (Canis Lupus Familiaris L., 1758)." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 113 (February 24, 2024): 54–61. http://dx.doi.org/10.32718/nvlvet11309.
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Each biological species of animals is unique in its structure, which is due to the uniqueness of ecological habitats and the peculiarities of adaptation of homeostasis mechanisms to the influence of environmental factors. Subtle differences in the structural and functional components of organs found in different species of animals create a clear architecture for understanding the depth of biological processes. Research of species, breed and age macro- and microanatomical structures and their morphometric indicators of organs and systems should be considered as urgent tasks of modern morphology. The new data on the morphological indicators of organs discovered at the macro- and micro-levels make a certain contribution to the age-related, breed-related, comparative, experimental and clinical morphology of mammals. Urinary organs in the body of mammals play one of the leading roles in maintaining the physiological and biochemical status of the organism and homeostasis as a whole, which largely depends directly on the morphological and functional state of these organs. Increasingly, there is a need for comprehensive scientific studies of various departments of the urinary organs. The scientific article uses material that is a fragment of the planned research work of the department of normal and pathological morphology, hygiene and expertise “Development, morphology and histochemistry of animal organs in normal and pathological conditions”, state registration number 0120U100796. The article contains the results of the morphometric characteristics of the kidneys of sexually mature dogs – Canis lupus familiaris L., 1758. During the implementation of this work, complex research methods were applied: anatomical, histological, morphometric and statistical. For histological examination, a fragment of kidneys was selected, they were fixed in 10 % neutral formalin solution, Carnois and Buena fluid. In the future, dehydration was carried out in alcohols of increasing concentration and the procedure for sealing the organ was carried out according to generally accepted methods. Using a sled microtome, histological sections with a thickness of 7–10 μm were obtained. Processing of the results of histological sections was examined under a “Micros” light microscope with a digital camera at a magnification of × 100–400. The morphological study of the structural organs of the urinary system was studied on histological sections by the method of light microscopy in accordance with the requirements of the international principles of the “European Convention for the Protection of Vertebrate Animals Used in Experiments and Other Scientific Purposes” (Strasbourg, 1986), by the decision of the First National Congress on Bioethics (M. Kyiv, 2001), Law of Ukraine No. 692 “On the Protection of Animals from Cruel Treatment” (3447-IV) dated February 21, 2006. According to the histological structure, the kidneys of dogs are represented by renal corpuscles and renal tubules, which are made of epithelial cells. Organometric studies indicate that the absolute mass of kidneys in sexually mature dogs is 119.8 ± 6.48 g, relative – 0.74 ± 0.04 %. Morphometric studies of the kidney parenchyma in dogs have established that the average area of renal corpuscles is 4.89 ± 0.24 thousand μm², the area of the vascular glomerulus is 3.79 ± 0.18 thousand μm², the area of the Shumlyansky-Bowman capsule lumen is 1.12 ± 0.27 thousand μm². The average volume of renal bodies of the cortical substance is 1265.69 ± 239.34 thousand μm³. The number of renal corpuscles per conventional unit of area (5 mm²) is 20.8 ± 0.6 units. The aim of the work was to investigate the peculiarities of the morphogistological structure of the kidneys of sexually mature dogs. The research results will expand information about the morphological structure, and will serve for the development of issues of physiology, pathology and treatment of diseases of the urinary organs.
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Rossi, Giovanni Maria, Chiara Pala, and Davide Gianfreda. "Renal and Urinary Tract Involvement in Fibrosclerosing or Fibroinflammatory Diseases: A Narrative Review." Rheumato 4, no. 1 (December 22, 2023): 1–12. http://dx.doi.org/10.3390/rheumato4010001.
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Fibroinflammatory diseases are a group of rare pathologies in which the hallmark is the exuberant deposition of fibrotic tissue and inflammatory cellular infiltrates, characteristic of the specific disease. A sclerotic mass develops within soft tissues and/or organs, damaging and replacing them, with effects ranging from asymptomatic to life-threatening clinical manifestations. The kidneys and urinary tract can be involved in some of these diseases, which can lead to acute kidney injury, chronic kidney disease, and even end-stage kidney disease. IgG4-related disease, retroperitoneal fibrosis, and Erdheim–Chester disease are the three fibroinflammatory disorders that can involve the kidneys. Only a timely and accurate collection of clinical, radiological, metabolic, laboratory, and histological data allows prompt diagnosis and targeted treatment of these pathologies, allowing the stoppage of the evolution of renal and systemic manifestations, which can lead to complete remission. The epidemiology, clinical and histological features, and management of these conditions are herein described in a narrative fashion.
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Hairil Akbar. "FAKTOR YANG BERHUBUNGAN DENGAN PERSONAL HYGIENE PADA REMAJA PUTRI DI SMA NEGERI 1 KOTAMOBAGU." Bina Generasi : Jurnal Kesehatan 11, no. 2 (March 17, 2020): 23–28. http://dx.doi.org/10.35907/bgjk.v11i2.148.
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Background: Adolescent girls are vulnerable to reproductive organ infections due to a lack of personal hygiene. Personal hygiene is an effort to maintain one's personal health with the purpose to prevent the occurrence of diseases and to improve health status. Problems that will arise due to lack of hygiene of the reproductive organs, namely some venereal diseases such as cervical cancer, vaginal discharge, genital skin irritation, allergies, and inflammation or urinary tract infections. Objective: The purpose of this study was to analyze factors related to personal hygiene. Method : This study applied observational analytic study with cross-sectional study approach and a sample of 100 female adolescents using a questionnaire. The sampling technique used simple random sampling and data analysis was done using the chi-square test. Result: The results of the analysis obtained knowledge (p-value = 0003) and socioeconomic status (p-value = 0,000). Conclusion: Therefore it can be inferred that knowledge and socioeconomic status were factors associated with personal hygiene in the female adolescents.
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MARINOU, K. "Abdominal ultrasonographic imaging of laboratory animals - Current techniques." Journal of the Hellenic Veterinary Medical Society 60, no. 3 (November 20, 2017): 245. http://dx.doi.org/10.12681/jhvms.14933.
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Diagnostic ultrasonography is a non-invasive imaging technique developed and applicable both in reproductive and companion animals for the diagnosis of diseases. During the last years it has also been used in laboratory animals facilitating thus the advances of biomedical research. The ultrasonographic imaging of abdominal organs in laboratory animals may take place in soft tissue organs, such as the liver, the spleen, the kidneys, the urinary bladder, but also the uterus, especially before, during and after pregnancy, as well as during parturition. It has been proved to be extremely useful both for monitoring of organ architecture during several related experimental protocols and for diagnosing possible diseases that may occur during a laboratory animal's lifetime. During the last decade technological progress has been present in scientific life leading in several advances in ultrasonographic imaging. More specifically, ultra high frequency transducers, with a potential of using sophisticated software, are now able to provide researchers with extended field of view images even of small laboratory animals, such as mice. 3D ultrasonography relies on the acquisition of images in multiple scan planes from which a 3D image is created. 4D ultrasonography provides functional data in three dimensions, whereas microbubble contrast agents have shown clinical potential for characterizing blood flow in abdominal vessels, especially with the use of ultra high frequency transducers and 3D imaging. Doppler imaging provides information on blood flow and abdominal organs blood supply. Finally, ultrasound- guided biopsy and injection of substances are important tools in biomedical research protocols.
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Dolat, Lee, Qicong Hu, and Elias T. Spiliotis. "Septin functions in organ system physiology and pathology." Biological Chemistry 395, no. 2 (February 1, 2014): 123–41. http://dx.doi.org/10.1515/hsz-2013-0233.
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Abstract Human septins comprise a family of 13 genes that encode for >30 protein isoforms with ubiquitous and tissue-specific expressions. Septins are GTP-binding proteins that assemble into higher-order oligomers and filamentous polymers, which associate with cell membranes and the cytoskeleton. In the last decade, much progress has been made in understanding the biochemical properties and cell biological functions of septins. In parallel, a growing number of studies show that septins play important roles for the development and physiology of specific tissues and organs. Here, we review the expression and function of septins in the cardiovascular, immune, nervous, urinary, digestive, respiratory, endocrine, reproductive, and integumentary organ systems. Furthermore, we discuss how the tissue-specific functions of septins relate to the pathology of human diseases that arise from aberrations in septin expression.
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Safonov, R. A., and V. V. Lazurenko. "Treatment of genital prolapse in elderly women with genitourinary infection." Bukovinian Medical Herald 27, no. 3 (107) (September 28, 2023): 50–56. http://dx.doi.org/10.24061/2413-0737.27.3.107.2023.9.
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Relevance of the study. Genital prolapse (GP) is a disease that unites a group of disorders of the muscular and ligamentous apparatus of the uterus and vagina, which lead to prolapse and prolapse of the internal genital organs. The incidence of HP in women over 50 reaches 50%, and among elderly and senile women, it increases to 60-70%. Frequent recurrence and the development of septic complications are characterised by urinary tract infections that occur against the background of genital abnormalities, hormone deficiency in the postmenopausal period, diabetes mellitus, asymptomatic bacteriuria, neurogenic bladder dysfunction, urinary incontinence, and surgical interventions on the genital or urinary system.The aim of the study is to optimize the treatment of genital prolapse (GP) in elderly women with urinary and genital infections. Materials and methods. We examined 70 elderly patients, including 20 (28.6%) with GP and infectious lesions of the urinary and genital organs (main group), 30 (42.8%) with GP without infectious lesions of the urinary and genital organs (comparison group), 20 (28.6%) women without gynaecological diseases and extragenital pathology (control group). The severity of the inflammatory process was assessed based on the study of complaints, anamnesis, and laboratory results. The degree of GP was determined using the POP-Q quantitative assessment system. The surgical intervention included transvaginal extirpation of the uterus without appendages, anterior colporrhaphy, colpoperineorrhaphy with levatoroplasty, and sacrospinal colpopexy. Before using the «Polymesh» synthetic mesh endoprosthesis, in order to minimise infectious complications caused by the use of synthetic prostheses, hydrodissection was performed with 0.9% sodium chloride saline (200 ml) with the addition of a third-generation cephalosporin antibiotic (1 g). Results of the study. Patients underwent uterine extirpation without vaginal appendages, unilateral sacrospinal colpopexy, anterior colporrhaphy, colpoperineorrhaphy with levatorrhaphy (in 6 (30%) women of the first group and 13 (43%) - of the second group). Uterine extirpation without vaginal appendages, sacrospinal colpopexy on the left using the «Polymesh» mesh prosthesis, anterior colporrhaphy, colpoperineorrhaphy with levatoroplasty - in 14 (70%) women of the first group and 17 (57%) of the second group. In case of stress urinary incontinence, a mid-urethral sling procedure was additionally performed (6 patients in the first group and 5 in the second). Women with genitourinary infection mainly underwent transvaginal uterine extirpation with unilateral sacrospinal colpopexy and the use of a synthetic mesh prosthesis «Polymesh». The volume of the operation in the form of uterine extirpation using the «Polymesh» prosthesis is due to the reliable effect of the mesh prosthesis in order to prevent the recurrence of the disease compared to sacrospinal colpopexy (1/4% of cases). Conclusions. Surgical treatment of genital prolapse in women with infectious lesions of the urinary and genital organs by using the «Polymesh» mesh prosthesis for colposacropexy after transvaginal uterine extirpation increases the effectiveness of its treatment, reducing the number of recurrences of the disease.
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Vercruysse, J., J. Fransen, V. R. Southgate, and D. Rollinson. "Pathology of Schistosoma curassoni infection in sheep." Parasitology 91, no. 2 (October 1985): 291–300. http://dx.doi.org/10.1017/s0031182000057383.
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The gross- and histopathology of natural and experimental Schistosoma curassoni infections in sheep were studied. The data obtained showed that S. curassoni infection in sheep causes only slight clinico-pathological manifestations with preferential involvement of the liver, the lower intestine and the urinary bladder. A variable spectrum of host reaction to the eggs within an individual animal was observed, reflecting the duration of presence of eggs in the organs. In the liver, egg granulomas were most numerous in the perilobular regions, while in the intestine, lesions were most pronounced in the mucosa of the rectum. The presence of eggs in 10% of the urinary bladders examined indicated some bladder involvement.
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Valimukhametova, D. A., V. N. Leonova, F. A. Reznikova, and S. K. Khamzina. "A case of in vivo diagnosis of generalized idiopathic amyloidosis." Kazan medical journal 69, no. 6 (December 15, 1988): 452–53. http://dx.doi.org/10.17816/kazmj99764.
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Idiopathic amyloidosis, unlike secondary amyloidosis, develops in the absence of previous disease. Its clinical presentation is multifaceted, determined by the lesion of certain organs and highly variable during the course of the disease. All manifestations of the disease are nonspecific. In contrast to secondary amyloidosis, idiopathic amyloidosis more often involves cardiovascular, respiratory, digestive and urinary systems. In vivo diagnosis of idiopathic amyloidosis is difficult due to its imitation of many diseases; in practice, it is recognized less often than it occurs.
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Pukhova, T. G., E. M. Spivak, and E. P. Sitnikova. "CLINICAL CHARACTERISTICS OF DISEASES OF URINARY SYSTEM ORGANS IN CHILDREN LIVING IN THE ZONE OF ECOLOGICAL DISTRESS." Вестник Смоленской государственной медицинской академии 21, no. 1 (2022): 233–36. http://dx.doi.org/10.37903/vsgma.2022.1.32.
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Katamanova, Elena V., Inna V. Tikhonova, Irina N. Kodinets, Natalya V. Kovalchuk, and Natalya A. Pavlenko. "Assessment of the state of health of teachers of secondary schools." Hygiene and sanitation 100, no. 12 (December 30, 2021): 1423–29. http://dx.doi.org/10.47470/0016-9900-2021-100-12-1423-1429.
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Introduction. Among the leading risk factors affecting the teaching contingent in their labour activity, psychoemotional stress, load on the vocal apparatus, hypodynamia, and prolonged forced posture are distinguished. As a result of hypodynamia - there is a violation of blood circulation, deterioration of the venous and lymphatic systems and further development of arterial hypertension (AH), overweight, varicose veins (VV), a decrease in the body’s immune forces, leading to frequent colds and chronic pathology of ENT organs. Therefore, the study of the health status of teachers, the prevention of diseases is an urgent task today. The purpose of the study is to assess the health status of teachers in general education schools based on many clinical and ultrasound examinations. Materials and methods. The object of the research was 78 teachers of secondary schools. All subjects were females, with an average age of 53.4 ± 8.3 years, an average work experience of 32.1 ± 9.1 years. Clinical and ultrasound examinations were carried out. Results. During clinical examination by narrow specialists, the detection of ENT organ pathology in the study group per 100 examined patients was 52 cases (66.6 ± 6.5%), 89 (114.1 ± 4.3%) cases - therapeutic pathology (among which arterial hypertension prevailed), 56 (71.8 ± 6.1%) cases of the endocrine system and 72 (92.3 ± 3.2%) cases of diseases of the nervous system. The frequency of pathological changes in the abdominal cavity and urinary system during screening ultrasound was 86% of cases, the thyroid gland - 70.0 ± 1.0% of cases. Conclusion. A clinical examination of the health status of teachers with more than ten years of experience has established one of the first places to be occupied by therapeutic pathology, in the form of CVS diseases, in the second place are diseases of the nervous system (vertebral pathology), the third-place belongs to diseases of the ENT organs and the endocrine system.
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SPINU, Dan, Dragos Radu MARCU, Ovidiu BRATU, Lucian IORGA, and Dan MISCHIANU. "Endometriosis in urology - an update." Medicina Moderna - Modern Medicine 28, no. 1 (March 29, 2021): 41–47. http://dx.doi.org/10.31689/rmm.2021.28.1.41.
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Introduction: Endometriosis represents the aberrant implantation of endometrial tissue, respectively outside the uterus. It is one of the gynecological diseases with a great impact on the patient’s quality of life and especially on the fertility aspects. Due to the aberrant implantation, this disease can theoretically affect any organ in the abdominal and retroperitoneal cavity. Thus, cases involving the organs of the urinary tract are not a surprise. Material and methods: The present paper focuses on the urological impairment of endometriosis, etiology according to various hypotheses and an update of existing treatment methods. The possible proposals of therapeutic guides found in the literature are also taken into account.Results: The urological condition of this disease seems to increase in frequency in recent years. If in the case of asymptomatic patients an expectant attitude can be approached in relative safety, the local invasive nature of the disease, which can lead to the loss of the function of the various organs of the urinary tract, must not be omitted. In the case of symptomatic patients, the treatment is either hormonal or surgical, lately there is a tendency to combine the two types of treatment. Being a condition with relatively rare urological involvement, the differential diagnosis often omits endometriosis. There are currently several plausible guide proposals, but it takes time and richer casuistry to be able to standardize them. From the point of view of surgical treatment, there is a tendency to introduce robotic surgery in the therapeutic arsenal of this disease, both in the case of classical endometriosis and in the case of urological involvement.
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Popoola, Ademola Alabi, J. O. Bello, G. G. Ezeoke, K. T. Adeshina, and A. Fadimu. "Concealed Enterovesical Fistula Associated with Forgotten Intra-Abdominal Haemostat and Intravesical Towel." Case Reports in Urology 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/723592.
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Introduction.Enterovesical fistula is rare and is often caused by bowel inflammatory diseases and tumours in the urinary bladder or the intestine with local infiltration of bowel or bladder, respectively. The fistula usually presents with lower urinary tract symptoms, pneumaturia, and faecaluria or with food particles in the urine. Intra-abdominal retained surgical foreign bodies have also been reported as causes.Case Presentation.A case of atypical presentation in a woman with enterovesical fistula following abdominal hysterectomy. Investigations confirmed the presence of surgical towel in the urinary bladder and a pair of artery forceps in the abdomen. The towel was removed at cystoscopy after which she presented with food particles in the urine. She later had laparatomy to remove the haemostat and to repair the fistula.Discussion.A typical presentation of enterovesical fistula delayed the diagnosis and treatment in this patient.Conclusion.Managing patients with recurrent urinary tract infection after abdominal operation should include appropriate imaging of the abdomen with emphasis on pelvic organs. Also, surgical operation should always be given the best shot the first time and strict operation room standards and guidelines should always be followed.
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Skovorodin, Evgeniy N., Georgiy V. Basekin, and Foat A. Karimov. "DIAGNOSIS OF URACHUS FISTULA IN FOALS." VESTNIK OF THE BASHKIR STATE AGRARIAN UNIVERSITY 68, no. 4 (2023): 114–17. http://dx.doi.org/10.31563/1684-7628-2023-68-4-114-117.
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In clinical and pathanatomic practice, doctors face a very heterogeneous group of human and animal diseases caused by a violation of the reduction of the urinary duct during embryogenesis. The pathology of urachus is a complex problem of humane and veterinary medicine. We conducted a thorough clinical study of foals who had pathology in the navel area. In case of death, the foal was opened and the organs of the urinary system, the umbilical vein and arteries were examined in detail. It was found that such foals did not have obliteration of the primary urinary duct (urachus) during the embryonic period and its flattening because of separation from the abdominal wall during labor. As a result, urine from the bladder got into the subcutaneous tissue, and then, after the umbilical cord stump fell off, it began to stand out through the umbilical opening. Complications of this pathological condition were edema, uremia, bleeding into the bladder, which led to respiratory arrest.
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Orabi, Hazem, Sara Bouhout, Amélie Morissette, Alexandre Rousseau, Stéphane Chabaud, and Stéphane Bolduc. "Tissue Engineering of Urinary Bladder and Urethra: Advances from Bench to Patients." Scientific World Journal 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/154564.
Full textAbstract:
Urinary tract is subjected to many varieties of pathologies since birth including congenital anomalies, trauma, inflammatory lesions, and malignancy. These diseases necessitate the replacement of involved organs and tissues. Shortage of organ donation, problems of immunosuppression, and complications associated with the use of nonnative tissues have urged clinicians and scientists to investigate new therapies, namely, tissue engineering. Tissue engineering follows principles of cell transplantation, materials science, and engineering. Epithelial and muscle cells can be harvested and used for reconstruction of the engineered grafts. These cells must be delivered in a well-organized and differentiated condition because water-seal epithelium and well-oriented muscle layer are needed for proper function of the substitute tissues. Synthetic or natural scaffolds have been used for engineering lower urinary tract. Harnessing autologous cells to produce their own matrix and form scaffolds is a new strategy for engineering bladder and urethra. This self-assembly technique avoids the biosafety and immunological reactions related to the use of biodegradable scaffolds. Autologous equivalents have already been produced for pigs (bladder) and human (urethra and bladder). The purpose of this paper is to present a review for the existing methods of engineering bladder and urethra and to point toward perspectives for their replacement.
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Marković, Marija, Dejan Pljevljakušić, and Vesna Stankov Jovanović. "Ethnopharmacological application of common agrimony (Agrimonia eupatoria) in the Pirot County (Serbia)." Etnobotanika 1, no. 1 (December 2021): 1–16. http://dx.doi.org/10.46793/etnbot21.01m.
Full textAbstract:
Agrimonia eupatoria is perennial herbaceous plant from family Rosaceae, characterized by pinnate leaves, and yellow spike-like racemose inflorescences. It flowers from June to September, and above ground part of plants are collected for medicinal purposes. Survey on participants' knowledge and use of medicinal plants in the Pirot County was carried in the form of interviews in four municipalities: Pirot, Babušnica, Bela Palanka and Dimitrovgrad. Out of the total number of respondents, which amounted to 631, it was noted that 34 people knew the use of common agrimony. The largest number of respondents mentioned common agrimony against the group of urinary diseases (19 reports). A small number of respondents have mentioned the use against prostate disease (6 reports) and treatment of wounds (5 reports). Five reports against the group of digestive tract diseases were recorded. The results were compared with other ethnopharmacological studies from Serbia and the Balkan Peninsula. The following applications of common agrimony were not mentioned in previous ethnopharmacological investigations in Serbia and Balkan Peninsula: for circulation, for the heart, against varicose veins, catarrh of the stomach, for colon, for the stomach, bile, liver, prostate disease, against kidney and urinary tract sand, and diseases of internal organs.
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Ziganshin, A. U., D. V. Bedova, E. A. Zubkov, and M. E. Sitdykova. "P2-receptors of the urinary bladder as potential targets for novel drugs." Kazan medical journal 99, no. 3 (June 15, 2018): 462–66. http://dx.doi.org/10.17816/kmj2018-462.
Full textAbstract:
Purinergic P2 receptors, the basic endogenous agonist of which is adenosine triphosphoric acid (ATP), are widely spread in the organs and tissues of human and animals including urogenitary system. Physiologically, in the peripheral nervous system the role of P2 receptors in most cases is not leading, they only complement or modulate the action of main neuromediators (acetylcholine, norepinephrine). But in pathology the role of P2 receptors significantly increases and often takes the lead in the pathogenesis of one or another disease. In particular, it was determined that purinergic component of contractile bladder response increases from 2-5% in normal state to 40% in some pathological processes (such as interstitial cystitis, neurogenic bladder, urinary obstruction). In the bladder of experimental animals different subtypes of P2 receptors were revealed, their functional role was established in normal conditions and models of pathological processes. Certain subtypes of P2 receptors were also detected in the human bladder, including in some urinary tract diseases. The level of ATP in patients’ urine was established to significantly increase in lower urinary tract obstruction that holds certain promise for the diagnosis of these diseases. Variety and large representation of P2 receptors in lower urinary tract make them attractive as potential targets for novel drugs. On this evidence, evaluation of effect of P2 receptor agonists and antagonists as well as medications affecting the metabolism of endogenous nucleotides and nucleosides, is one of promising direction for the search for new urological drugs.
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Agarkov, Alexander, Anatoly Dmitriev, N. Agarkov, A. Shulunova, and A. Sidelnikov. "Morphofunctional changes assessment in newborn piglets in early postnatal ontogenesis complicated by isoimmunization symptoms." E3S Web of Conferences 210 (2020): 06025. http://dx.doi.org/10.1051/e3sconf/202021006025.
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It is known that the pathological course of pregnancy is associated with a violation in the mutually dependent complex “mother-fetus” and leads to specific clinical consequences at the molecular-cellular, tissue, organ, organismic and population levels of the organization. Pathogenic action mechanism of the isoimmunization effect is very complex and still remains insufficiently deciphered. However, changes in the system of organs responsible for adaptation and survival play an important role in the pathogenesis of morphofunctional disorders associated with isoimmunization. Therefore, in farms where the fact of isoimmunization state is established, it is necessary to pay special attention to the creation of conditions that contribute to the normalization of the functional systems of adaptation of newborn animals. The material for research was the lungs, intestines, kidneys, and thymus. Only fresh material was examined. Samples up to 0.5 cm thick were taken for histological examination after forced slaughter. Fixation was performed with a neutral aqueous 10% formalin solution. Histological sections 4-6 microns thick were made from the obtained paraffin blocks, which were stained with hematoxylin and eosin for review purposes. When describing the morphofunctional state of organs, the structure, cellular composition, and condition of blood vessels were observed. Isoimmunization of sows during pregnancy is manifested by a characteristic clinical and morphological complex that differs from other infectious and non-infectious diseases. The most characteristic pathomorphological signs are: hypoplasia, delayed differentiation, dystrophic changes in the respiratory, digestive, urinary systems and organs of immunogenesis.
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Torshin, I. Yu, A. М. Lila, O. A. Limanova, and O. A. Gromova. "Prospects for the use of chondroitin sulfate and glucosamine sulfate with osteoarthritis associated with pathology of the kidneys and urinary system." FARMAKOEKONOMIKA. Modern Pharmacoeconomic and Pharmacoepidemiology 13, no. 1 (April 24, 2020): 23–34. http://dx.doi.org/10.17749/2070-4909.2020.13.1.23-34.
Full textAbstract:
Introduction. Chondroitin sulfate (CS) and glucosamine sulfate (GS), widely used as chondroprotectors, can maintain the normal functioning of the urinary system but their effect has not been analyzed systematically.Aim: to perform a systematic analysis of the possibilities of using CS and GS in patients with pathology of the kidneys and urinary system.Materials and methods. Predictive analysis of 2,093 publications on the interactions of CS/GS with the functioning of the kidneys and other organs of the urinary system found at the request “(urinary OR bladder OR kidney) AND (glucosamine OR chondroitin)” by methods of the theory of topological data analysis.Results. Disorders of cholesterol and glucosamine metabolism are characteristic of cystitis, glomerular nephritis, urinary tract infections (UTIs), urolithiasis, proteinuria, and formation of diabetic nephropathy. In addition to inhibiting the pro-inflammatory cascade NF-kB, CS/GS contribute to eliminating the deficiency of glycosaminoglycans in the pathology of urothelium, inhibit urolithiasis, inhibit the synthesis of pro-inflammatory nitric oxide NO in macrophages, and modulate O-glycosylation processes.Conclusion. The results of fundamental and clinical studies show that subsidies of CS/GS substances of pharmacological quality per os and CS instillation in the bladder (in particular, in combination with hyaluronic acid) are the means of choice for patients suffering from osteoarthritis and diseases of the urinary system. Highly purified pharmacological CS substances are part of the preparation Chondroguard.
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Sieg, Michael, Johannes Busch, Maria Eschke, Denny Böttcher, Kristin Heenemann, Annett Vahlenkamp, Anja Reinert, et al. "A New Genotype of Feline Morbillivirus Infects Primary Cells of the Lung, Kidney, Brain and Peripheral Blood." Viruses 11, no. 2 (February 9, 2019): 146. http://dx.doi.org/10.3390/v11020146.
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Paramyxoviruses comprise a large number of diverse viruses which in part give rise to severe diseases in affected hosts. A new genotype of feline morbillivirus, tentatively named feline morbillivirus genotype 2 (FeMV-GT2), was isolated from urine of cats with urinary tract diseases. Whole genome sequencing showed about 78% nucleotide homology to known feline morbilliviruses. The virus was isolated in permanent cell lines of feline and simian origin. To investigate the cell tropism of FeMV-GT2 feline primary epithelial cells from the kidney, the urinary bladder and the lung, peripheral blood mononuclear cells (PBMC), as well as organotypic brain slice cultures were used for infection experiments. We demonstrate that FeMV-GT2 is able to infect renal and pulmonary epithelial cells, primary cells from the cerebrum and cerebellum, as well as immune cells in the blood, especially CD4+ T cells, CD20+ B cells and monocytes. The cats used for virus isolation shed FeMV-GT2 continuously for several months despite the presence of neutralizing antibodies in the blood. Our results point towards the necessity of increased awareness for this virus when clinical signs of the aforementioned organs are encountered in cats which cannot be explained by other etiologies.
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Liu, Minghui, and Ke Zen. "Toll-Like Receptors Regulate the Development and Progression of Renal Diseases." Kidney Diseases 7, no. 1 (December 10, 2020): 5–14. http://dx.doi.org/10.1159/000511947.
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<b><i>Background:</i></b> Stimulated by both microbial and endogenous ligands, toll-like receptors (TLRs) play an important role in the development and progression of renal diseases. <b><i>Summary:</i></b> As a highly conserved large family, TLRs have 11 members in humans (TLR1∼TLR11) and 13 members in mouse (TLR1∼TLR13). It has been widely reported that TLR2 and TLR4 signaling, activated by both exogenous and endogenous ligands, promote disease progression in both renal ischemia-reperfusion injury and diabetic nephropathy. TLR4 also vitally functions in CKD and infection-associated renal diseases such as pyelonephritis induced by urinary tract infection. Stimulation of intracellular TLR7/8 and TLR9 by host-derived nucleic acids also plays a key role in systemic lupus erythematosus. Given that certain microRNAs with GU-rich sequence have recently been found to be able to serve as TLR7/8 ligands, these microRNAs may initiate pro-inflammatory signal via activating TLR signal. Moreover, as microRNAs can be transferred across different organs via cell-secreted exosomes or protein-RNA complex, the TLR signaling activated by the miRNAs released by other injured organs may also result in renal dysfunction. <b><i>Key Messages:</i></b> In this review, we sum up the recent progress in the role of TLRs in various forms of glomerulonephritis and discuss the possible prevention or therapeutic strategies for clinic treatment to renal diseases.
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Malhotra, Meenakshi, Pooja Tandon, Kritika Wadhwa, Indu Melkani, Ajeet Pal Singh, and Amar Pal Singh. "The complex pathophysiology of urolithiasis (kidney stones) and the effect of combinational drugs." Journal of Drug Delivery and Therapeutics 12, no. 5-S (October 15, 2022): 194–204. http://dx.doi.org/10.22270/jddt.v12i5-s.5718.
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Body organs are very crucial when it comes to homeostatically maintaining them. If any changes occur in their function, it may lead to the development of diseases in the body. The kidney is one of the functionalised organs that is connected with the ureter and urinary bladder, which is basically the lower part of the body. The kidney priorly controls the volume of various body fluids, fluid osmolality, acid-base balance, various electrolyte concentrations, and the removal of toxins. Any dis-balance in the function of the kidney can generate a disease like renal calculi (kidney stone), chronic kidney disease (CKD), polycystic kidney disease (PKD), urinary tract infections (UTI), etc. Kidney stones (KS) are prevalent worldwide, affecting 15% of individuals. A stone arranged into various sizes may be micro, macro, and nano or found as mono or polycrystalline forms. The names of the two most common kidney stones, calcium and non-calcium stones (Uric acid stones, struvite stones, cysteine stones, and drug-induced KS), are determined primarily by their composition. Calcium stones are commonly found in individuals, approximately 80% of KS. This review provided recent details on kidney stone symptoms, etiology, psychophysiology, and management perspective.
Keywords: Kidney disease, calcium stone, renal calculi, chronic kidney disease, Polycystic kidney disease.